首页 > 最新文献

Archives of Suicide Research最新文献

英文 中文
Examining Trajectories of Momentary Affect Surrounding NSSI and Alcohol Use: A Network Analysis and Bayesian Approach. 研究自伤和酒精使用的瞬间影响轨迹:网络分析和贝叶斯方法。
IF 2 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-10-01 Epub Date: 2025-02-14 DOI: 10.1080/13811118.2025.2462532
Miguel Blacutt, Brooke A Ammerman

Objectives: This study aimed to identify specific affective antecedents of non-suicidal self-injury (NSSI) and alcohol use, and to examine affective trajectories before and after these behaviors.

Method: Fifty-six undergraduates (71% female, 25% non-White, 20.2 ± 1.3 years old) meeting criteria for probable alcohol or substance use disorder participated in 28-days of ecological momentary assessment, completing four daily surveys assessing affect, self-punishment cognitions, and engagement in NSSI and alcohol use. Contemporaneous and time-lagged graphical vector autoregressive (GVAR) models were used to examine affect dynamics surrounding NSSI and alcohol use. Zero-inflated Bayesian binomial regression was used to investigate the relationship between momentary affect and likelihood of engaging in either NSSI or alcohol at the next prompt. Multilevel modeling was used to examine trajectories of affective states pre- and post-engagement in NSSI and alcohol use.

Results: GVAR models revealed significant relationships between jitteriness and being afraid with next timepoint NSSI, and excitement with next timepoint alcohol use. Bayesian regression with horseshoe priors identified self-punishment and loneliness as predictors of NSSI. Moreover, Bayesian regression revealed that excitement predicted alcohol use among those without alcohol use disorder (AUD), while belongingness predicted alcohol use among those with AUD. Multilevel models revealed self-punishment and loneliness followed a negative quadratic trajectory around NSSI events. Excitement and belongingness did not relate to slopes of time.

Conclusions: The findings suggest NSSI is used to reduce negative emotional states, whereas alcohol consumption initially enhances positive emotional states in individuals without an AUD and may be used to increase belongingness in those with an AUD.

目的:本研究旨在确定非自杀性自伤(NSSI)和酒精使用的特定情感前因,并检查这些行为前后的情感轨迹。方法:56名符合可能酒精或物质使用障碍标准的大学生(71%为女性,25%为非白人,20.2±1.3岁)参加了为期28天的生态瞬时评估,每天完成4次调查,评估自伤和酒精使用的影响、自我惩罚认知和参与。同时和滞后的图形向量自回归(GVAR)模型被用来检验自伤和酒精使用的影响动态。使用零膨胀贝叶斯二项回归来调查瞬时情感与下一次自伤或酗酒的可能性之间的关系。多层次模型被用来检验自伤和酒精使用前后的情感状态轨迹。结果:GVAR模型揭示了下一个时间点自伤时的紧张和害怕以及下一个时间点饮酒时的兴奋之间的显著关系。马蹄形先验贝叶斯回归发现自我惩罚和孤独是自伤的预测因子。此外,贝叶斯回归显示,兴奋预测无酒精使用障碍(AUD)者的酒精使用,而归属感预测有AUD者的酒精使用。多层次模型显示,自我惩罚和孤独感在自伤事件周围呈负二次曲线。兴奋和归属感与时间的斜率无关。结论:研究结果表明,自伤被用来减少消极情绪状态,而酒精消费最初会增强没有AUD的个体的积极情绪状态,并可能被用来增加AUD患者的归属感。
{"title":"Examining Trajectories of Momentary Affect Surrounding NSSI and Alcohol Use: A Network Analysis and Bayesian Approach.","authors":"Miguel Blacutt, Brooke A Ammerman","doi":"10.1080/13811118.2025.2462532","DOIUrl":"10.1080/13811118.2025.2462532","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to identify specific affective antecedents of non-suicidal self-injury (NSSI) and alcohol use, and to examine affective trajectories before and after these behaviors.</p><p><strong>Method: </strong>Fifty-six undergraduates (71% female, 25% non-White, 20.2 ± 1.3 years old) meeting criteria for probable alcohol or substance use disorder participated in 28-days of ecological momentary assessment, completing four daily surveys assessing affect, self-punishment cognitions, and engagement in NSSI and alcohol use. Contemporaneous and time-lagged graphical vector autoregressive (GVAR) models were used to examine affect dynamics surrounding NSSI and alcohol use. Zero-inflated Bayesian binomial regression was used to investigate the relationship between momentary affect and likelihood of engaging in either NSSI or alcohol at the next prompt. Multilevel modeling was used to examine trajectories of affective states pre- and post-engagement in NSSI and alcohol use.</p><p><strong>Results: </strong>GVAR models revealed significant relationships between jitteriness and being afraid with next timepoint NSSI, and excitement with next timepoint alcohol use. Bayesian regression with horseshoe priors identified self-punishment and loneliness as predictors of NSSI. Moreover, Bayesian regression revealed that excitement predicted alcohol use among those without alcohol use disorder (AUD), while belongingness predicted alcohol use among those with AUD. Multilevel models revealed self-punishment and loneliness followed a negative quadratic trajectory around NSSI events. Excitement and belongingness did not relate to slopes of time.</p><p><strong>Conclusions: </strong>The findings suggest NSSI is used to reduce negative emotional states, whereas alcohol consumption initially enhances positive emotional states in individuals without an AUD and may be used to increase belongingness in those with an AUD.</p>","PeriodicalId":8325,"journal":{"name":"Archives of Suicide Research","volume":" ","pages":"1011-1029"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143424855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk Factors for Suicide in Pakistan: A Mixed Methods Study of Psychological Autopsies and Perspectives of Health Professionals. 巴基斯坦自杀的危险因素:心理解剖和卫生专业人员观点的混合方法研究。
IF 2 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-10-01 Epub Date: 2024-12-17 DOI: 10.1080/13811118.2024.2436635
Syeda Ayat-E-Zainab Ali, Tamkeen Saleem, S M Yasir Arafat

Background: Suicide is a significant but understudied public health concern in developing nations like Pakistan, where risks factors have not been investigated by mixed methods studies. Hence, we aimed to explore the risk factors for suicide based on a mixed methodology.

Methods: This study followed a mixed methods convergent component design. A retrospective case-control psychological autopsy with a semistructured interview protocol was performed. Additionally, health professionals' opinions on the psychiatric risk factors for suicide were assessed through qualitative interviews. Data were collected between 2021 and 2022 and analyzed by SPSS (V-25) and thematic analysis (NVIVO-12 Plus).

Results: Based on the mixed methods meta-inferences, suicidal ideation; depression; hopelessness; social isolation; previous history of self-harm and traumatic experiences; lack of motivation; purposelessness; feeling like a burden; substance abuse; impulsivity; anger; anxiety; psychiatric disorders such as personality disorders, bipolar disorder, schizophrenia, gaming addiction, and eating disorders; and family history of psychiatric illness were identified as risk factors for suicide.

Conclusion: More must be learned about the mental health components contributing to suicide and the culturally appropriate prevention methods used in Pakistan. This study reveals novel targets for suicide prevention and may aid policymaking by providing a better understanding of predictors and specific psychiatric characteristics of suicide in Pakistan.

背景:在巴基斯坦等发展中国家,自杀是一个重要但研究不足的公共卫生问题,这些国家的危险因素尚未通过混合方法研究进行调查。因此,我们的目的是在混合方法的基础上探讨自杀的危险因素。方法:本研究采用混合方法收敛组件设计。采用半结构化访谈方案进行回顾性病例-对照心理解剖。此外,透过质性访谈,评估卫生专业人员对自杀精神危险因素的看法。数据收集于2021年至2022年,并通过SPSS (V-25)和专题分析(NVIVO-12 Plus)进行分析。结果:基于混合方法的元推断,自杀意念;抑郁症;绝望;社会隔离;有自残史和创伤经历;缺乏动力;无目的;感觉像负担;药物滥用;冲动;愤怒;焦虑;精神疾病,如人格障碍、双相情感障碍、精神分裂症、游戏成瘾和饮食失调;精神疾病家族史被认为是自杀的危险因素。结论:必须更多地了解导致自杀的心理健康因素以及在巴基斯坦使用的文化上适当的预防方法。这项研究揭示了自杀预防的新目标,并可能通过更好地了解巴基斯坦自杀的预测因素和特定的精神特征来帮助政策制定。
{"title":"Risk Factors for Suicide in Pakistan: A Mixed Methods Study of Psychological Autopsies and Perspectives of Health Professionals.","authors":"Syeda Ayat-E-Zainab Ali, Tamkeen Saleem, S M Yasir Arafat","doi":"10.1080/13811118.2024.2436635","DOIUrl":"10.1080/13811118.2024.2436635","url":null,"abstract":"<p><strong>Background: </strong>Suicide is a significant but understudied public health concern in developing nations like Pakistan, where risks factors have not been investigated by mixed methods studies. Hence, we aimed to explore the risk factors for suicide based on a mixed methodology.</p><p><strong>Methods: </strong>This study followed a mixed methods convergent component design. A retrospective case-control psychological autopsy with a semistructured interview protocol was performed. Additionally, health professionals' opinions on the psychiatric risk factors for suicide were assessed through qualitative interviews. Data were collected between 2021 and 2022 and analyzed by SPSS (V-25) and thematic analysis (NVIVO-12 Plus).</p><p><strong>Results: </strong>Based on the mixed methods meta-inferences, suicidal ideation; depression; hopelessness; social isolation; previous history of self-harm and traumatic experiences; lack of motivation; purposelessness; feeling like a burden; substance abuse; impulsivity; anger; anxiety; psychiatric disorders such as personality disorders, bipolar disorder, schizophrenia, gaming addiction, and eating disorders; and family history of psychiatric illness were identified as risk factors for suicide.</p><p><strong>Conclusion: </strong>More must be learned about the mental health components contributing to suicide and the culturally appropriate prevention methods used in Pakistan. This study reveals novel targets for suicide prevention and may aid policymaking by providing a better understanding of predictors and specific psychiatric characteristics of suicide in Pakistan.</p>","PeriodicalId":8325,"journal":{"name":"Archives of Suicide Research","volume":" ","pages":"891-910"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142833790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and Association of Suicidal Ideation and High Risk Drinking in Men and Women: Results from a Representative German Household Survey. 自杀意念和高危饮酒在男性和女性中的流行程度及其关联:来自一项有代表性的德国家庭调查的结果。
IF 2 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-10-01 Epub Date: 2025-02-21 DOI: 10.1080/13811118.2025.2464061
Jim Schmeckenbecher, Nestor D Kapusta, Christina Alma Emilian, Elmar Brähler, Victor Blüml, Jürgen Fuchshuber, Mareike Ernst

Background: Alcohol abuse and suicide are significant public health problems. Specifically, more than three million people die each year from alcohol abuse and 700,000 from suicide. Research indicates that alcohol abuse is associated with suicidality, and that there are significant gender differences in both. By means of a large representative population sample, this study quantifies the associations between suicidal ideation and alcohol misuse in the German population.

Methods: Based on a survey of 2,513 individuals from 2015, prevalence estimates and logistic regression models were used to estimate the association between suicidal ideation (i.e., past-year suicidal ideation according to the Suicidal Behavior Questionnaire Revised [SBQ-R] and alcohol consumption (i.e., past year high-risk drinking according to the Alcohol Use Disorders Identification Test [AUDIT-C]).

Results: High-risk drinking (24.78%) and suicidal ideation (5.09%) were highly prevalent in this representative German population sample. These estimates differed significantly between men and women: Men were more likely to report high-risk drinking (30.14%) compared to women (20.56%), while a greater proportion of women (5.95%) reported suicidal ideation when compared to men (4.00%). Moreover, the association of suicidal ideation and high-risk drinking was weaker in women (OR = 1.64 CI 95% [1.03-2.62]) than in men (OR = 5.62 CI 95% [2.72-11.60]).

Conclusion: The high prevalence of suicidal ideation and high-risk drinking in women and underscores the necessity for low-level interventions and public health initiatives aimed at prevention and intervention against the escalation of high-risk drinking and suicidal behavior. Prevention efforts should consider gender-specific patterns of risk.

背景:酗酒和自杀是严重的公共卫生问题。具体来说,每年有300多万人死于酗酒,70万人死于自杀。研究表明,酒精滥用与自杀有关,而且两者之间存在显著的性别差异。通过大量代表性人口样本,本研究量化了德国人口中自杀意念和酒精滥用之间的联系。方法:基于2015年对2513人的调查,采用流行率估计和logistic回归模型估计自杀意念(即根据自杀行为问卷修订版[SBQ-R]过去一年的自杀意念)与酒精消费(即根据酒精使用障碍识别测试[审计- c]过去一年的高危饮酒)之间的关系。结果:高危饮酒(24.78%)和自杀意念(5.09%)在这个具有代表性的德国人群样本中非常普遍。这些估计在男性和女性之间存在显著差异:男性(30.14%)比女性(20.56%)更有可能报告高风险饮酒,而女性(5.95%)比男性(4.00%)更有可能报告自杀意念。此外,自杀意念与高危饮酒的相关性在女性中较弱(OR = 1.64 CI 95%[1.03-2.62]),在男性中较弱(OR = 5.62 CI 95%[2.72-11.60])。结论:妇女自杀意念和高危饮酒的高流行率强调了低水平干预和公共卫生倡议的必要性,旨在预防和干预高危饮酒和自杀行为的升级。预防工作应考虑到不同性别的风险模式。
{"title":"Prevalence and Association of Suicidal Ideation and High Risk Drinking in Men and Women: Results from a Representative German Household Survey.","authors":"Jim Schmeckenbecher, Nestor D Kapusta, Christina Alma Emilian, Elmar Brähler, Victor Blüml, Jürgen Fuchshuber, Mareike Ernst","doi":"10.1080/13811118.2025.2464061","DOIUrl":"10.1080/13811118.2025.2464061","url":null,"abstract":"<p><strong>Background: </strong>Alcohol abuse and suicide are significant public health problems. Specifically, more than three million people die each year from alcohol abuse and 700,000 from suicide. Research indicates that alcohol abuse is associated with suicidality, and that there are significant gender differences in both. By means of a large representative population sample, this study quantifies the associations between suicidal ideation and alcohol misuse in the German population.</p><p><strong>Methods: </strong>Based on a survey of 2,513 individuals from 2015, prevalence estimates and logistic regression models were used to estimate the association between suicidal ideation (i.e., past-year suicidal ideation according to the Suicidal Behavior Questionnaire Revised [SBQ-R] and alcohol consumption (i.e., past year high-risk drinking according to the Alcohol Use Disorders Identification Test [AUDIT-C]).</p><p><strong>Results: </strong>High-risk drinking (24.78%) and suicidal ideation (5.09%) were highly prevalent in this representative German population sample. These estimates differed significantly between men and women: Men were more likely to report high-risk drinking (30.14%) compared to women (20.56%), while a greater proportion of women (5.95%) reported suicidal ideation when compared to men (4.00%). Moreover, the association of suicidal ideation and high-risk drinking was weaker in women (OR = 1.64 CI 95% [1.03-2.62]) than in men (OR = 5.62 CI 95% [2.72-11.60]).</p><p><strong>Conclusion: </strong>The high prevalence of suicidal ideation and high-risk drinking in women and underscores the necessity for low-level interventions and public health initiatives aimed at prevention and intervention against the escalation of high-risk drinking and suicidal behavior. Prevention efforts should consider gender-specific patterns of risk.</p>","PeriodicalId":8325,"journal":{"name":"Archives of Suicide Research","volume":" ","pages":"1030-1042"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143466717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigating the Role of Racism in Black Men's Suicide: Revisiting the Interpersonal-Psychological Theory of Suicide. 调查种族主义在黑人自杀中的作用:重新审视自杀的人际心理学理论。
IF 2 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-10-01 Epub Date: 2025-02-13 DOI: 10.1080/13811118.2025.2462528
Leslie B Adams, Aubrey DeVinney, Dahlia Aljuboori, Jasmin Brooks Stephens, Thomasina Watts, Benjamin Lê Cook, Sean Joe, Holly C Wilcox, Roland J Thorpe

Objective: The Interpersonal-Psychological Theory of Suicide (IPTS) is a well-established framework to assess suicide risk, yet few studies have applied the framework to examine relevance and applicability to suicide phenomenology in Black American men. We address this gap by qualitatively exploring the suitability of the IPTS framework using a psychiatric sample of Black men.

Method: We conducted semi-structured interviews with 15 Black adult men (Mean age = 32.1, min:18, max: 79) with a history of suicidal thoughts and behaviors (STBs). We conducted thematic analysis using an inductive and deductive coding approach using Dedoose v. 8.

Results: Overall, IPTS constructs were represented in participant narratives. Thwarted belongingness emerged as the most prominent construct of the theory, followed by hopelessness, and suicide capability. Participants noted the role of racism in their STB from multiple levels, including internalized, interpersonal, and structural racism.

Conclusions: Black men reported aspects of the Interpersonal Psychological Theory of Suicide (IPTS), notably experiences of social isolation, which were often attributed to racism. Our findings highlight the relative importance of certain IPTS constructs among Black men, namely the significance of thwarted belongingness and its relationship with social marginalization. Our findings identify future areas of expansion for the IPTS framework to capture broader sociocultural dynamics in racialized populations.

目的:人际自杀心理理论(IPTS)是一个完善的评估自杀风险的框架,但很少有研究将该框架应用于美国黑人男性自杀现象学的相关性和适用性。我们通过使用黑人精神病学样本定性地探索IPTS框架的适用性来解决这一差距。方法:我们对15名有自杀念头和行为史的黑人成年男性(平均年龄32.1岁,最小年龄18岁,最大年龄79岁)进行了半结构化访谈。我们使用Dedoose v. 8进行了主题分析,采用归纳和演绎编码方法。结果:总体而言,IPTS构念在参与者叙述中得到体现。受挫的归属感成为该理论最突出的结构,其次是绝望和自杀能力。参与者从内化、人际和结构性种族主义等多个层面指出了种族主义在其STB中的作用。结论:黑人男性报告了人际自杀心理理论(IPTS)的各个方面,特别是社会孤立的经历,这通常归因于种族主义。我们的研究结果强调了某些IPTS结构在黑人男性中的相对重要性,即受挫归属感的重要性及其与社会边缘化的关系。我们的研究结果确定了未来IPTS框架的扩展领域,以捕捉种族化人群中更广泛的社会文化动态。
{"title":"Investigating the Role of Racism in Black Men's Suicide: Revisiting the Interpersonal-Psychological Theory of Suicide.","authors":"Leslie B Adams, Aubrey DeVinney, Dahlia Aljuboori, Jasmin Brooks Stephens, Thomasina Watts, Benjamin Lê Cook, Sean Joe, Holly C Wilcox, Roland J Thorpe","doi":"10.1080/13811118.2025.2462528","DOIUrl":"10.1080/13811118.2025.2462528","url":null,"abstract":"<p><strong>Objective: </strong>The Interpersonal-Psychological Theory of Suicide (IPTS) is a well-established framework to assess suicide risk, yet few studies have applied the framework to examine relevance and applicability to suicide phenomenology in Black American men. We address this gap by qualitatively exploring the suitability of the IPTS framework using a psychiatric sample of Black men.</p><p><strong>Method: </strong>We conducted semi-structured interviews with 15 Black adult men (Mean age = 32.1, min:18, max: 79) with a history of suicidal thoughts and behaviors (STBs). We conducted thematic analysis using an inductive and deductive coding approach using Dedoose v. 8.</p><p><strong>Results: </strong>Overall, IPTS constructs were represented in participant narratives. Thwarted belongingness emerged as the most prominent construct of the theory, followed by hopelessness, and suicide capability. Participants noted the role of racism in their STB from multiple levels, including internalized, interpersonal, and structural racism.</p><p><strong>Conclusions: </strong>Black men reported aspects of the Interpersonal Psychological Theory of Suicide (IPTS), notably experiences of social isolation, which were often attributed to racism. Our findings highlight the relative importance of certain IPTS constructs among Black men, namely the significance of thwarted belongingness and its relationship with social marginalization. Our findings identify future areas of expansion for the IPTS framework to capture broader sociocultural dynamics in racialized populations.</p>","PeriodicalId":8325,"journal":{"name":"Archives of Suicide Research","volume":" ","pages":"997-1010"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12343918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143413144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sexual Fluidity and Suicidal Thoughts and Behaviors in Early and Middle Adulthood: Evidence From the National Longitudinal Study of Adolescent to Adult Health. 成年早期和中期的性流动性与自杀念头和行为:来自青少年到成人健康的全国纵向研究的证据。
IF 2 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-10-01 Epub Date: 2025-01-03 DOI: 10.1080/13811118.2024.2445244
John F Gunn, Zoe Brown, James Ambron

Objective: The present study seeks to explore the relationship between sexual fluidity and suicidal thoughts (STs) and behaviors (STBs) among adults in early and middle adulthood.

Methods: This study utilized data from Waves IV and V of the National Longitudinal Study of Adolescent to Adult Health (ADD Health). Participants were categorized into four groups: (1) heterosexual at both waves, (2) sexual minority (SM) at Wave IV but heterosexual at Wave V, (3) heterosexual at Wave IV and SM at Wave V, and (4) SM at Wave IV and Wave V.

Results: Hierarchical logistic regression revealed that sexual fluidity between Waves IV and V was associated with STs. Those who were heterosexual-identifying at Wave IV but identified as an SM at Wave V were close to four times as likely to report STs at Wave V than were those who identified as heterosexual at both waves. Those who were an SM at Waves IV and V were almost twice as likely to report STs compared to those who were heterosexual at both waves. Additionally, χ2 results showed that suicide attempts (SAs) and sexual fluidity were associated. Similarly, SA prevalence was highest during periods in which participants identified as SMs.

Conclusions: Transitioning into a sexually minoritized status is associated with increased risk of STBs, whereas transitioning into a nonminoritized status was not.

目的:探讨性流动性与成年早期和中期成人自杀念头和行为的关系。方法:本研究利用了国家青少年到成人健康纵向研究(ADD Health)第四和第五波的数据。参与者被分为四组:(1)两波都是异性恋者;(2)第四波的性少数(SM)但第五波是异性恋者;(3)第四波的异性恋者和第五波的SM;(4)第四波和第五波的SM。结果:层次逻辑回归显示,第四波和第五波之间的性流动性与STs有关。那些在第四次浪潮中被认定为异性恋,但在第五次浪潮中被认定为SM的人,在第五次浪潮中被认定为STs的可能性是在两次浪潮中都被认定为异性恋者的近四倍。在第四波和第五波中是SM的人报告性侵犯的可能性几乎是在两波中都是异性恋的人的两倍。此外,χ2结果显示自杀企图(SAs)与性流动性相关。同样,SA患病率最高的时期,参与者确定为SMs。结论:变性为性少数群体与性传播感染风险增加相关,而变性为非少数群体与性传播感染风险无关。
{"title":"Sexual Fluidity and Suicidal Thoughts and Behaviors in Early and Middle Adulthood: Evidence From the National Longitudinal Study of Adolescent to Adult Health.","authors":"John F Gunn, Zoe Brown, James Ambron","doi":"10.1080/13811118.2024.2445244","DOIUrl":"10.1080/13811118.2024.2445244","url":null,"abstract":"<p><strong>Objective: </strong>The present study seeks to explore the relationship between sexual fluidity and suicidal thoughts (STs) and behaviors (STBs) among adults in early and middle adulthood.</p><p><strong>Methods: </strong>This study utilized data from Waves IV and V of the National Longitudinal Study of Adolescent to Adult Health (ADD Health). Participants were categorized into four groups: (1) heterosexual at both waves, (2) sexual minority (SM) at Wave IV but heterosexual at Wave V, (3) heterosexual at Wave IV and SM at Wave V, and (4) SM at Wave IV and Wave V.</p><p><strong>Results: </strong>Hierarchical logistic regression revealed that sexual fluidity between Waves IV and V was associated with STs. Those who were heterosexual-identifying at Wave IV but identified as an SM at Wave V were close to four times as likely to report STs at Wave V than were those who identified as heterosexual at both waves. Those who were an SM at Waves IV and V were almost twice as likely to report STs compared to those who were heterosexual at both waves. Additionally, <i>χ</i><sup>2</sup> results showed that suicide attempts (SAs) and sexual fluidity were associated. Similarly, SA prevalence was highest during periods in which participants identified as SMs.</p><p><strong>Conclusions: </strong>Transitioning into a sexually minoritized status is associated with increased risk of STBs, whereas transitioning into a nonminoritized status was not.</p>","PeriodicalId":8325,"journal":{"name":"Archives of Suicide Research","volume":" ","pages":"969-981"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142919589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Suicidal Behaviour Prior to First Episode Psychosis: Wider and More Widespread Grey-Matter Alterations. 首次精神病发作前的自杀行为:更广泛和更广泛的灰质改变。
IF 2 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-10-01 Epub Date: 2025-02-05 DOI: 10.1080/13811118.2025.2454581
M Canal-Rivero, D Tordesillas-Gutiérrez, M Ruiz-Veguilla, V Ortiz-García de la Foz, E Marco de Lucas, R Romero-Garcia, J Vázquez-Bourgon, R Ayesa-Arriola, B Crespo-Facorro

Introduction: The prodromal phase preceding the onset of First Episode Psychosis (FEP) is associated with an increased risk of Suicidal Behaviors (SBs). The aim of this study was to identify specific structural brain abnormalities linked to SBs that occur prior to the onset of FEP.

Methods: Voxel-based morphometry analyses were used to investigate differences in brain Grey Matter (GM) volume using the CAT12 toolbox within SPM12. Covariates, including gender, age, handedness, intracranial volume, depression severity, and global cognitive functioning, were controlled for as confounding factors.

Results: Significant reductions in GM were observed in the left superior temporal gyrus, dorsal posterior cingulate cortex, precuneus, cuneus, anterior cerebellum (p-FWE corrected < 0.05, k > 50) as well as in the right amygdala (0.96 ± 0.06 vs. 1.01 ± 0.05; F = 4.78; p < 0.05) and left amygdala (0.97 ± 0.06 vs. 1.02 ± 0.05; F = 8.97; p = 0.01).

Conclusions: History of SB prior to the onset of the psychotic disorder was related to wider and more widespread brain GM alterations. The regions identified are involved in cognitive and emotional processes such as emotional regulation, social cognition, perseverative thinking, and pain tolerance. These findings suggest that structural brain abnormalities related to SB occurring before FEP onset may serve as early biomarkers for identifying individuals at increased risk of suicide.

前言:首发精神病(FEP)发病前的前驱期与自杀行为(SBs)的风险增加有关。本研究的目的是确定在FEP发病前与SBs相关的特定脑结构异常。方法:使用SPM12中的CAT12工具箱,采用基于体素的形态学分析方法研究脑灰质(GM)体积的差异。包括性别、年龄、利手性、颅内容积、抑郁严重程度和整体认知功能在内的协变量作为混杂因素进行了控制。结果:左侧颞上回、后扣带皮层背侧、楔前叶、楔前叶、小脑前部(p-FWE校正< 0.05,k - bbb50)及右侧杏仁核GM显著降低(0.96±0.06∶1.01±0.05;f = 4.78;p p = 0.01)。结论:精神障碍发病前的SB病史与更广泛和更广泛的脑GM改变有关。这些区域涉及认知和情感过程,如情绪调节、社会认知、持久思维和疼痛耐受。这些发现表明,在FEP发病前与SB相关的脑结构异常可能作为识别自杀风险增加个体的早期生物标志物。
{"title":"Suicidal Behaviour Prior to First Episode Psychosis: Wider and More Widespread Grey-Matter Alterations.","authors":"M Canal-Rivero, D Tordesillas-Gutiérrez, M Ruiz-Veguilla, V Ortiz-García de la Foz, E Marco de Lucas, R Romero-Garcia, J Vázquez-Bourgon, R Ayesa-Arriola, B Crespo-Facorro","doi":"10.1080/13811118.2025.2454581","DOIUrl":"10.1080/13811118.2025.2454581","url":null,"abstract":"<p><strong>Introduction: </strong>The prodromal phase preceding the onset of First Episode Psychosis (FEP) is associated with an increased risk of Suicidal Behaviors (SBs). The aim of this study was to identify specific structural brain abnormalities linked to SBs that occur prior to the onset of FEP.</p><p><strong>Methods: </strong>Voxel-based morphometry analyses were used to investigate differences in brain Grey Matter (GM) volume using the CAT12 toolbox within SPM12. Covariates, including gender, age, handedness, intracranial volume, depression severity, and global cognitive functioning, were controlled for as confounding factors.</p><p><strong>Results: </strong>Significant reductions in GM were observed in the left superior temporal gyrus, dorsal posterior cingulate cortex, precuneus, cuneus, anterior cerebellum (p-FWE corrected < 0.05, <i>k</i> > 50) as well as in the right amygdala (0.96 ± 0.06 vs. 1.01 ± 0.05; F = 4.78; <i>p</i> < 0.05) and left amygdala (0.97 ± 0.06 vs. 1.02 ± 0.05; F = 8.97; <i>p</i> = 0.01).</p><p><strong>Conclusions: </strong>History of SB prior to the onset of the psychotic disorder was related to wider and more widespread brain GM alterations. The regions identified are involved in cognitive and emotional processes such as emotional regulation, social cognition, perseverative thinking, and pain tolerance. These findings suggest that structural brain abnormalities related to SB occurring before FEP onset may serve as early biomarkers for identifying individuals at increased risk of suicide.</p>","PeriodicalId":8325,"journal":{"name":"Archives of Suicide Research","volume":" ","pages":"982-996"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143188006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Do Positive Gatekeeper Training Outcomes Predict Gatekeeper Intervention Behaviours? 积极的守门人培训结果能预测守门人的干预行为吗?
IF 2 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-10-01 Epub Date: 2025-02-23 DOI: 10.1080/13811118.2025.2469882
Glenn Holmes, Amanda Clacy, Anita Hamilton, Kairi Kõlves

Objective: Evidence for Gatekeeper Training (GKT) has shown that training outcomes are generally maintained at follow-up. Research on how improvements in GKT outcomes translate to intervention behavior is inconclusive, and some studies show that despite significant positive effects on GKT outcomes, there is no effect on GK behaviors.

Method: A non-experimental pre-post and follow-up survey design was used with a sample of 60 participants who voluntarily completed one of 12 half-day (4-hour) GKT sessions. Path Analysis was applied to pre- and post-intervention training outcomes, and a third model assessed the behavioral effect of the change in participant scores from pre- to post.

Results: Suicide prevention knowledge retained by participants at 6-months after GKT was predictive of increased GK behavior in the 6-months following GKT. Knowledge at follow-up was the only significant predictor of behavior (p < .05), no other regression pathways were significant.

Conclusions: Gatekeeper preparedness, efficacy, and reluctance outcomes were not predictive of GK behavior. The findings of this study represent a lack of understanding regarding how the specific aims of GKT are translated into intervention behavior to identify, intervene, support, and refer potentially at-risk individuals.

目的:看门人培训(GKT)的证据表明,培训结果通常在随访中保持不变。关于GKT结果的改善如何转化为干预行为的研究尚无定论,一些研究表明,尽管对GKT结果有显著的积极影响,但对GK行为没有影响。方法:采用非实验的前后随访调查设计,对60名自愿完成12个半天(4小时)GKT课程之一的参与者进行抽样调查。路径分析应用于干预前和干预后的训练结果,第三个模型评估了参与者得分从干预前到干预后变化的行为影响。结果:参与者在GKT后6个月保留的自杀预防知识可预测GKT后6个月自杀行为的增加。随访时的知识是行为的唯一显著预测因子(p < 0.05),其他回归途径均不显著。结论:看门人的准备、有效性和不情愿结果不能预测GK行为。本研究的结果表明,对于如何将GKT的具体目标转化为干预行为,以识别、干预、支持和转介潜在风险个体,缺乏理解。
{"title":"Do Positive Gatekeeper Training Outcomes Predict Gatekeeper Intervention Behaviours?","authors":"Glenn Holmes, Amanda Clacy, Anita Hamilton, Kairi Kõlves","doi":"10.1080/13811118.2025.2469882","DOIUrl":"10.1080/13811118.2025.2469882","url":null,"abstract":"<p><strong>Objective: </strong>Evidence for Gatekeeper Training (GKT) has shown that training outcomes are generally maintained at follow-up. Research on how improvements in GKT outcomes translate to intervention behavior is inconclusive, and some studies show that despite significant positive effects on GKT outcomes, there is no effect on GK behaviors.</p><p><strong>Method: </strong>A non-experimental pre-post and follow-up survey design was used with a sample of 60 participants who voluntarily completed one of 12 half-day (4-hour) GKT sessions. Path Analysis was applied to pre- and post-intervention training outcomes, and a third model assessed the behavioral effect of the change in participant scores from pre- to post.</p><p><strong>Results: </strong>Suicide prevention knowledge retained by participants at 6-months after GKT was predictive of increased GK behavior in the 6-months following GKT. Knowledge at follow-up was the only significant predictor of behavior (<i>p</i> < .05), no other regression pathways were significant.</p><p><strong>Conclusions: </strong>Gatekeeper preparedness, efficacy, and reluctance outcomes were not predictive of GK behavior. The findings of this study represent a lack of understanding regarding how the specific aims of GKT are translated into intervention behavior to identify, intervene, support, and refer potentially at-risk individuals.</p>","PeriodicalId":8325,"journal":{"name":"Archives of Suicide Research","volume":" ","pages":"1043-1056"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Designing Social Media Messages to Promote Action by Suicide Gatekeepers. 设计社交媒体信息以促进自杀看门人的行动。
IF 2 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-10-01 Epub Date: 2024-12-11 DOI: 10.1080/13811118.2024.2438211
Megan M Cox, Glenn Leshner

Objective: Suicide prevention professionals and programs have focused on reaching not only individuals with suicide ideation, but also family, friends, and other acquaintances, referred to as suicide gatekeepers. Social media provide platforms that allow health communicators to reach a large population. This research focuses on examining and testing the most effective message framing (how the message provides a reward or consequence for the receiver) and message construct (precise focus and wording of a message) for social media posts intended to positively influence suicide gatekeeper intervention behavior on behalf of a friend or peer.

Method: An experiment tested the influence of message construct (between subjects) and message frame (within subjects). The experiment randomized the 1285 participants between the ages of 18 and 34 into the three message construct conditions (significance, preventability, and beneficence).

Results: The results suggest gain-framed messages have a more positive influence than loss-framed messages on all social media message outcome variables (likelihood of social media message engagement, perceived message effectiveness, self-efficacy, response efficacy, empathy, and behavioral expectation), and state empathy mediates the relationship between message frame and these variables. Message construct condition and other mediation results were less substantial, although some evidence suggests that the significance message construct may increase social media message sharing and perceived message effectiveness.

Conclusion: Results show strong evidence of the effectiveness of using gain frames in social media messages aimed at suicide gatekeepers. Other considerations include highlighting the significance of suicide and utilizing empathy appeals to strengthen social media message engagement and behavioral intention.

目的:自杀预防专业人员和项目不仅关注有自杀意念的个人,还关注家庭、朋友和其他熟人,这些人被称为自杀看门人。社交媒体提供平台,使卫生传播者能够接触到大量人群。本研究的重点是检查和测试社交媒体帖子中最有效的信息框架(信息如何为接受者提供奖励或结果)和信息结构(信息的精确焦点和措辞),这些帖子旨在积极影响代表朋友或同伴的自杀看门人干预行为。方法:通过实验测试信息结构(被试之间)和信息框架(被试内部)的影响。实验将1285名年龄在18岁至34岁之间的参与者随机分为三个信息构建条件(重要性、可预防性和有益性)。结果:所得框架信息对社交媒体信息结果变量(社交媒体信息参与可能性、感知信息有效性、自我效能、反应效能、共情和行为期望)的影响大于失框架信息,状态共情在信息框架与这些变量的关系中起中介作用。虽然有证据表明,重要性信息结构可以增加社交媒体信息分享和感知信息有效性,但信息结构条件和其他中介结果不太实质性。结论:研究结果有力地证明了在针对自杀看门人的社交媒体信息中使用增益框架的有效性。其他考虑因素包括强调自杀的重要性,利用同理心呼吁来加强社交媒体信息的参与和行为意图。
{"title":"Designing Social Media Messages to Promote Action by Suicide Gatekeepers.","authors":"Megan M Cox, Glenn Leshner","doi":"10.1080/13811118.2024.2438211","DOIUrl":"10.1080/13811118.2024.2438211","url":null,"abstract":"<p><strong>Objective: </strong>Suicide prevention professionals and programs have focused on reaching not only individuals with suicide ideation, but also family, friends, and other acquaintances, referred to as suicide gatekeepers. Social media provide platforms that allow health communicators to reach a large population. This research focuses on examining and testing the most effective message framing (how the message provides a reward or consequence for the receiver) and message construct (precise focus and wording of a message) for social media posts intended to positively influence suicide gatekeeper intervention behavior on behalf of a friend or peer.</p><p><strong>Method: </strong>An experiment tested the influence of message construct (between subjects) and message frame (within subjects). The experiment randomized the 1285 participants between the ages of 18 and 34 into the three message construct conditions (significance, preventability, and beneficence).</p><p><strong>Results: </strong>The results suggest gain-framed messages have a more positive influence than loss-framed messages on all social media message outcome variables (likelihood of social media message engagement, perceived message effectiveness, self-efficacy, response efficacy, empathy, and behavioral expectation), and state empathy mediates the relationship between message frame and these variables. Message construct condition and other mediation results were less substantial, although some evidence suggests that the significance message construct may increase social media message sharing and perceived message effectiveness.</p><p><strong>Conclusion: </strong>Results show strong evidence of the effectiveness of using gain frames in social media messages aimed at suicide gatekeepers. Other considerations include highlighting the significance of suicide and utilizing empathy appeals to strengthen social media message engagement and behavioral intention.</p>","PeriodicalId":8325,"journal":{"name":"Archives of Suicide Research","volume":" ","pages":"925-941"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142805921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and Associations of Suicidal Thoughts and Suicide Attempts by Sexual Orientation Among Students in Lithuania. 立陶宛学生的性取向与自杀念头及自杀企图的关系。
IF 2 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-09-30 DOI: 10.1080/13811118.2025.2565500
Jokūbas Gužas, Paulius Skruibis

Objective: Research indicates that non-heterosexual students face a higher risk of suicidal thoughts and attempts compared to heterosexual peers. However, differences in suicidal behavior between sexual orientation groups among students in Lithuania remain underexplored.

Method: Data were collected via an online survey of students from 17 higher education institutions in Lithuania. Participants answered sociodemographic questions, reported suicidal thoughts and attempts at various time periods, and completed the PHQ-4. Prevalence was calculated for the full sample and sexual orientation groups. Logistic regression examined associations between suicidal behavior and sexual orientation, controlling for confounding variables.

Results: The full sample included 2,012 participants (ages 18-29, M = 21.62, SD = 2.35), of whom 13.5% identified as bisexual and 4.4% as lesbian/gay. Suicidal thoughts were reported by 40.7%-63.6% of heterosexual, 53.4%-76.1% of lesbian/gay students, and 66.5%-89.7% of bisexual students. Suicide attempts were reported by 1.0%-15.0% of heterosexual, 2.3%-20.5% of lesbian/gay, and 4.1%-25.8% of bisexual students. Lesbian/gay students had higher odds of suicidal behavior compared to heterosexual students (AOR = 1.710, 95% CI [1.017, 2.875]), while bisexuals exhibited even higher odds (AOR 1.710-4.197, 95% CI [1.242, 6.047]). Bisexuals also showed higher odds compared to lesbian/gay students (AOR 2.529-2.626, 95% CI [1.307, 4.895]).

Conclusions: A higher proportion of non-heterosexual students in Lithuania report suicidal thoughts and attempts compared to heterosexual counterparts. The findings further underscore a relationship between sexual orientation and suicidal behavior, with bisexual students exhibiting the highest vulnerability.

目的:研究表明,与异性恋同龄人相比,非异性恋学生面临更高的自杀念头和企图风险。然而,立陶宛学生中不同性取向群体的自杀行为差异仍未得到充分研究。方法:通过对立陶宛17所高等教育机构的学生进行在线调查收集数据。参与者回答了社会人口学问题,报告了不同时期的自杀想法和尝试,并完成了PHQ-4。计算了整个样本和性取向群体的患病率。逻辑回归检验了自杀行为和性取向之间的联系,控制了混杂变量。结果:完整样本包括2012名参与者(18-29岁,M = 21.62, SD = 2.35),其中13.5%为双性恋,4.4%为女同性恋/男同性恋。有自杀念头的异性恋学生占40.7% ~ 63.6%,女同性恋/男同性恋学生占53.4% ~ 76.1%,双性恋学生占66.5% ~ 89.7%。有自杀企图的异性恋学生占1.0%-15.0%,女同性恋/男同性恋学生占2.3%-20.5%,双性恋学生占4.1%-25.8%。女同性恋/男同性恋学生的自杀行为发生率高于异性恋学生(AOR = 1.710, 95% CI[1.017, 2.875]),而双性恋学生的自杀行为发生率更高(AOR = 1.710-4.197, 95% CI[1.242, 6.047])。与女同性恋/男同性恋学生相比,双性恋学生的患病几率也更高(AOR为2.529-2.626,95% CI[1.307, 4.895])。结论:与异性恋学生相比,立陶宛的非异性恋学生报告有自杀念头和企图的比例更高。研究结果进一步强调了性取向和自杀行为之间的关系,双性恋学生表现出最高的脆弱性。
{"title":"Prevalence and Associations of Suicidal Thoughts and Suicide Attempts by Sexual Orientation Among Students in Lithuania.","authors":"Jokūbas Gužas, Paulius Skruibis","doi":"10.1080/13811118.2025.2565500","DOIUrl":"https://doi.org/10.1080/13811118.2025.2565500","url":null,"abstract":"<p><strong>Objective: </strong>Research indicates that non-heterosexual students face a higher risk of suicidal thoughts and attempts compared to heterosexual peers. However, differences in suicidal behavior between sexual orientation groups among students in Lithuania remain underexplored.</p><p><strong>Method: </strong>Data were collected via an online survey of students from 17 higher education institutions in Lithuania. Participants answered sociodemographic questions, reported suicidal thoughts and attempts at various time periods, and completed the PHQ-4. Prevalence was calculated for the full sample and sexual orientation groups. Logistic regression examined associations between suicidal behavior and sexual orientation, controlling for confounding variables.</p><p><strong>Results: </strong>The full sample included 2,012 participants (ages 18-29, <i>M</i> = 21.62, <i>SD</i> = 2.35), of whom 13.5% identified as bisexual and 4.4% as lesbian/gay. Suicidal thoughts were reported by 40.7%-63.6% of heterosexual, 53.4%-76.1% of lesbian/gay students, and 66.5%-89.7% of bisexual students. Suicide attempts were reported by 1.0%-15.0% of heterosexual, 2.3%-20.5% of lesbian/gay, and 4.1%-25.8% of bisexual students. Lesbian/gay students had higher odds of suicidal behavior compared to heterosexual students (AOR = 1.710, 95% CI [1.017, 2.875]), while bisexuals exhibited even higher odds (AOR 1.710-4.197, 95% CI [1.242, 6.047]). Bisexuals also showed higher odds compared to lesbian/gay students (AOR 2.529-2.626, 95% CI [1.307, 4.895]).</p><p><strong>Conclusions: </strong>A higher proportion of non-heterosexual students in Lithuania report suicidal thoughts and attempts compared to heterosexual counterparts. The findings further underscore a relationship between sexual orientation and suicidal behavior, with bisexual students exhibiting the highest vulnerability.</p>","PeriodicalId":8325,"journal":{"name":"Archives of Suicide Research","volume":" ","pages":"1-14"},"PeriodicalIF":2.0,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neural Correlates Involved in Behavioral Metrics of Emotion Regulation and Suicidal Thoughts and Behaviors. 情绪调节行为指标与自杀念头和行为的神经关联。
IF 2 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-09-20 DOI: 10.1080/13811118.2025.2560362
Simon M Li, Veronika Kobrinsky, Kiyan Irani, Aayushi Sangani, Qimin Liu

Given the well-documented association between emotion regulation (ER) deficits and suicidal thoughts and behaviors (STBs), and the limited understanding of their neural mechanisms, we reviewed studies across five databases that included validated ER tasks and neuroimaging techniques such as functional magnetic resonance imaging and electroencephalography. This systematic review synthesizes evidence from 11 neuroimaging studies to explore the neural correlates of ER deficits in individuals with STBs. Findings revealed that individuals with STBs exhibit heightened activation in the dorsolateral and ventrolateral prefrontal cortex during ER tasks, alongside increased amygdala reactivity to negative stimuli (e.g., sad facial expressions), in implicit ER paradigms. Heterogeneity in prefrontal cortex activation suggests that task- and population-specific neural signatures may influence these patterns. Our review also identifies methodological limitations in the current literature, including a reliance on cross-sectional designs and small sample sizes, which limit generalizability. These limitations highlight the need for longitudinal and multi-modal studies to better understand the dynamic neural patterns associated with ER and STBs. By elucidating the neural underpinnings of ER deficits in STBs, these findings may enable earlier identification of at-risk individuals and the development of personalized, targeted interventions (e.g., transcranial magnetic stimulation).

鉴于情绪调节(ER)缺陷与自杀想法和行为(STBs)之间的关联已被充分证明,而对其神经机制的了解有限,我们回顾了五个数据库中的研究,包括经过验证的ER任务和功能磁共振成像和脑电图等神经成像技术。本系统综述综合了11项神经影像学研究的证据,以探讨性传播感染患者内质网缺损的神经相关性。研究结果显示,在内啡肽任务中,STBs个体的背外侧和腹外侧前额叶皮层的激活增强,同时,在内隐内啡肽范式中,杏仁核对负面刺激(如悲伤的面部表情)的反应增强。前额皮质激活的异质性表明,特定任务和群体的神经特征可能会影响这些模式。我们的综述还指出了当前文献中方法上的局限性,包括对横断面设计和小样本量的依赖,这限制了通用性。这些局限性突出了纵向和多模态研究的必要性,以更好地了解与内窥线和stb相关的动态神经模式。通过阐明性传播疾病内质网缺损的神经基础,这些发现可能有助于更早地识别高危个体,并开发个性化的、有针对性的干预措施(例如,经颅磁刺激)。
{"title":"Neural Correlates Involved in Behavioral Metrics of Emotion Regulation and Suicidal Thoughts and Behaviors.","authors":"Simon M Li, Veronika Kobrinsky, Kiyan Irani, Aayushi Sangani, Qimin Liu","doi":"10.1080/13811118.2025.2560362","DOIUrl":"https://doi.org/10.1080/13811118.2025.2560362","url":null,"abstract":"<p><p>Given the well-documented association between emotion regulation (ER) deficits and suicidal thoughts and behaviors (STBs), and the limited understanding of their neural mechanisms, we reviewed studies across five databases that included validated ER tasks and neuroimaging techniques such as functional magnetic resonance imaging and electroencephalography. This systematic review synthesizes evidence from 11 neuroimaging studies to explore the neural correlates of ER deficits in individuals with STBs. Findings revealed that individuals with STBs exhibit heightened activation in the dorsolateral and ventrolateral prefrontal cortex during ER tasks, alongside increased amygdala reactivity to negative stimuli (e.g., sad facial expressions), in implicit ER paradigms. Heterogeneity in prefrontal cortex activation suggests that task- and population-specific neural signatures may influence these patterns. Our review also identifies methodological limitations in the current literature, including a reliance on cross-sectional designs and small sample sizes, which limit generalizability. These limitations highlight the need for longitudinal and multi-modal studies to better understand the dynamic neural patterns associated with ER and STBs. By elucidating the neural underpinnings of ER deficits in STBs, these findings may enable earlier identification of at-risk individuals and the development of personalized, targeted interventions (e.g., transcranial magnetic stimulation).</p>","PeriodicalId":8325,"journal":{"name":"Archives of Suicide Research","volume":" ","pages":"1-21"},"PeriodicalIF":2.0,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145102557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Archives of Suicide Research
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1