Archives of Women's Mental Health最新文献

{"title":"Global prevalence and associated factors of severe fear of childbirth: a systematic review and Meta-Analysis","authors":"Mahsa Maghalian,&nbsp;Zohreh Alizadeh-Dibazari,&nbsp;Mojgan Mirghafourvand","doi":"10.1007/s00737-025-01648-0","DOIUrl":"10.1007/s00737-025-01648-0","url":null,"abstract":"<div><h3>Background</h3><p>Fear of childbirth (FoC), particularly its severe form (tokophobia), is a significant public health concern associated with adverse maternal and neonatal outcomes. While previous meta-analyses have provided global prevalence estimates, significant knowledge gaps remain due to limited studies. This study aimed to provide an updated global prevalence estimate of severe FoC and explore sources of heterogeneity and associated risk factors.</p><h3>Methods</h3><p>A systematic review and meta-analysis was conducted following PRISMA and MOOSE guidelines. We searched international and Persian databases from inception until June 2025 for cross-sectional and cohort studies reporting severe FoC prevalence in pregnant women using validated tools with defined cutoffs. Two reviewers independently performed data extraction and quality assessment using the Newcastle-Ottawa Scale. Random-effects models were used for meta-analysis, with heterogeneity assessed via I² statistic. Subgroup analyses and meta-regressions explored variation sources. Risk factors were synthesized descriptively, though nulliparity and unplanned pregnancy allowed meta-analysis.</p><h3>Results</h3><p>From 67 included studies (<i>n</i> = 905,504 participants), the pooled prevalence of severe FoC was 16.5% (95% CI: 13.8–19.5%), with significant heterogeneity (I² = 99.45%). Assessment tools and cutoffs were major heterogeneity sources (<i>p</i> &lt; 0.001), with prevalence ranging from 3.7% to 58.7%. Country of study was also a significant moderator (<i>p</i> &lt; 0.001). Meta-regression showed no significant association with maternal age, gestational age, nulliparity percentage, or publication year. Key risk factors included previous traumatic birth, anxiety/depression symptoms, and inadequate social support. Nulliparous women had higher odds of severe FoC (OR = 1.36, 95% CI: 1.04–1.76), as did those with unplanned pregnancy (OR = 1.85, 95% CI: 1.29–2.65).</p><h3>Conclusion</h3><p>Severe FoC affects approximately one in six women globally. The substantial heterogeneity, largely due to methodological variations, underscores the need for standardized assessment protocols. Identified associations with factors such as previous traumatic birth and anxiety highlight the condition’s multifactorial nature, emphasizing the importance of targeted screening and evidence-based interventions aligned with Sustainable Development Goal (SDG) 3 to improve maternal mental health.</p></div>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"29 1","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145886847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Family Planning Belief Index (FPBI) as a measure to refurbish contraceptive counselling: evidence from Rural Odisha, India","authors":"Sonali Kar,&nbsp;Pramod Chandra Samantaray","doi":"10.1007/s00737-025-01627-5","DOIUrl":"10.1007/s00737-025-01627-5","url":null,"abstract":"","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"28 6","pages":"1561 - 1562"},"PeriodicalIF":2.7,"publicationDate":"2025-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00737-025-01627-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145676453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Turkısh women’s experıences of early and forced marrıage: a meta-synthesıs study","authors":"Büşra Dolkun,&nbsp;Muazez Küçükkaya,&nbsp;Nur Elçin Boyacıoğlu","doi":"10.1007/s00737-025-01625-7","DOIUrl":"10.1007/s00737-025-01625-7","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;p&gt;The prevalence of early or forced marriage among women in Türkiye is 24.2%. The limited knowledge of family planning among these young women leads to higher rates of unintended pregnancies, postnatal depression, frequent and early pregnancies, as well as an increase in health-compromising miscarriages and curettages, which collectively contribute to elevated maternal and child mortality rates.&lt;/p&gt;&lt;h3&gt;Aim&lt;/h3&gt;&lt;p&gt;The study seeks to construct a comprehensive and nuanced understanding of the marital experiences of women in Türkiye who were married at a young age or against their will. By synthesizing descriptive findings from qualitative studies, the research aims to develop analytical themes illuminating the multifaceted dimensions of these experiences.&lt;/p&gt;&lt;h3&gt;Design&lt;/h3&gt;&lt;p&gt;A systematic review and meta-synthesis. Meta-ethnography, one of the meta-synthesis methods, was used.&lt;/p&gt;&lt;h3&gt;Data sources&lt;/h3&gt;&lt;p&gt;A systematic literature search was conducted across six databases: Google Scholar, Cochrane, PubMed, Web of Science, ScienceDirect, and YÖK Thesis. Only studies conducted in Türkiye and published in English or Turkish were included in the study. Men and minority groups (immigrant, LGBTQI+, etc.) were not included in the study. The year of marriage or participant age was not limited to obtain comprehensive results.&lt;/p&gt;&lt;h3&gt;Review methods&lt;/h3&gt;&lt;p&gt;Reporting of the different phases of the literature search followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) checklist. The quality of the selected studies was evaluated using the Critical Appraisal Skills Programme (CASP) for qualitative research. We used thematic synthesis to analyse and synthesise the evidence, and we used the GRADE-CERQual (Confidence in the Evidence from Reviews of Qualitative research) approach to assess our confidence in each finding.&lt;/p&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;p&gt;The overarching theme, “Turkish women’s experiences of early and forced marriage,” is subdivided into three analytical themes: factors driving early marriage, consequences of early marriage, and coping mechanisms and preventive measures. A comprehensive search was conducted in six electronic databases for qualitative studies published up to 2024, with no publication date limitation. A total of 67,745 articles were identified through the database search. As a result of the screening, 528 abstracts and 236 full texts were screened, and finally, 28 articles were included in the meta-synthesis process.&lt;/p&gt;&lt;h3&gt;Conclusions&lt;/h3&gt;&lt;p&gt;Women subjected to early marriages report enduring physical, psychological, and sexual abuse inflicted by their spouses and in-laws. These women also report encountering significant challenges during pregnancy, childbirth, the postpartum period, and motherhood. This study underscores the need for considering the intricate connections among causes, consequences, and coping mechanisms within the marriage process to prevent early and forced marriages effect","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"28 6","pages":"1385 - 1409"},"PeriodicalIF":2.7,"publicationDate":"2025-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145480820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal attachment interventions: a comprehensive systematic review and meta-analysis","authors":"John J. Coté,&nbsp;Danielle B. Dilsaver,&nbsp;James Dimmock,&nbsp;Pooja Doehrman,&nbsp;Samantha Teague,&nbsp;Remington D. Coté,&nbsp;Brayden P. Coté,&nbsp;Riley Kilzer,&nbsp;Mahsa Omrani Sabbaghi,&nbsp;Jessica L. Borelli,&nbsp;Suena H. Massey","doi":"10.1007/s00737-025-01630-w","DOIUrl":"10.1007/s00737-025-01630-w","url":null,"abstract":"<div><h3>Purpose</h3><p>Amidst a rapidly growing worldwide literature on non-invasive interventions to optimize parent–child relationships prenatally, the effectiveness of prenatal attachment intervention remains uncertain due to methodologic restrictions of prior systematic reviews. The current systematic review was aimed at capturing the diversity of study designs, intervention targets and methods employed reflective of this burgeoning literature. We then employed meta-regression to evaluate the impact of expected heterogeneity on estimated intervention effects.</p><h3>Methods</h3><p>We searched MEDLINE/PubMed, Scopus, PsychINFO, Trip database, and Google Scholar for empirical prenatal attachment intervention studies published through August 11, 2025, with titles and abstracts written in English. Articles with main texts written in other languages were translated prior to analysis (PROSPERO ID CRD42021241199).</p><h3>Results</h3><p>Prenatal attachment scores increased following intervention when examining all studies (p &lt; . 001), randomized controlled trials only (p &lt; .001), and studies of only male expectant parents (<i>p</i> = .017). Specific intervention methods found to be effective were touch and Leopold’s maneuver (<i>p</i> = .004), fetal movement counting (<i>p</i> &lt; .001), music, lullaby and singing (<i>p</i> = .012), relaxation techniques (<i>p</i> = .014), cognitive therapies (<i>p</i> = .022), meditation (<i>p</i> = .003), breathing exercises (<i>p</i> = .001), and educational interventions (<i>p</i> &lt; .001).</p><h3>Conclusions</h3><p>While the prior systematic reviews of prenatal attachment interventions involving a total of 15 randomized controlled trials suggested equivocal effects of prenatal intervention, evidence from the current more inclusive review of non-randomized control trial (RCT) studies testing a wide range of intervention methods was substantially more compelling. More research on prenatal attachment in non-pregnant expectant partners and other caregivers and on promising but understudied interventions involving music and 3D fetal ultrasound images is recommended.</p></div>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"28 6","pages":"1447 - 1471"},"PeriodicalIF":2.7,"publicationDate":"2025-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00737-025-01630-w.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145470360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding the nature of interpersonal relationships through the interpretations of young female cannabis users in Iran","authors":"Nika Armanisadr,&nbsp;Azam Farah Bijari,&nbsp;Zohreh Khosravi","doi":"10.1007/s00737-025-01624-8","DOIUrl":"10.1007/s00737-025-01624-8","url":null,"abstract":"<div><h3>Purpose</h3><p>Cannabis use has increased markedly in Iran, emerging as the second most commonly consumed illicit substance, with a notable rise among women. Interpersonal relationships play a critical role in shaping behaviors and patterns of substance use. This study examines how young women who use cannabis interpret their interpersonal relationships.</p><h3>Methods</h3><p>A thematic narrative analysis was conducted in Karaj and Tehran from 2022 to 2023. Twelve young women who use cannabis were recruited through purposive and snowball sampling methods. Semi-structured interviews were conducted until data saturation was reached. Interview data were analyzed using open coding and thematic analysis to identify key relational dynamics related to cannabis use.</p><h3>Results</h3><p>A total of 961 open codes were generated and organized into two overarching themes. The first theme, “A Triad of Dysfunctional Interpersonal Relationships—Father, Mother, and Child,”, comprising 447 codes, illustrated how maladaptive familial interactions contributed to the initiation and persistence of cannabis use. The second theme, “Positive and Negative Qualities of Interpersonal Relationships Across Childhood, Adolescence, and Early Adulthood,”, encompassed 514 codes and five subthemes. While some participants reported receiving emotional support from peers or family members, the prevailing narrative involved experiences of emotional neglect, parent–child conflict, and the absence of secure attachment figures. These relational challenges were frequently cited as key drivers of the initiation and persistence of cannabis use, employed as a coping mechanism in response to unresolved emotional needs and relational distress.</p><h3>Conclusion</h3><p>The findings indicate that early experiences of family dysfunction and unresolved relational trauma substantially shape patterns of cannabis use among young women in Iran. Preventive strategies should include parent-focused educational interventions on emotional communication, family cohesion, and support structures. Additionally, increased access to psychosocial support and counseling services for young women is essential to mitigate risk and address underlying relational vulnerabilities.</p></div>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"28 6","pages":"1547 - 1559"},"PeriodicalIF":2.7,"publicationDate":"2025-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145470357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multimodal large language models for women’s reproductive mental health","authors":"Rawan AlSaad,&nbsp;Alaa Youssef,&nbsp;Sara Kashani,&nbsp;Majid AlAbdulla,&nbsp;Alaa Abd-alrazaq,&nbsp;Salma M. Khaled,&nbsp;Arfan Ahmed,&nbsp;Javaid Sheikh","doi":"10.1007/s00737-025-01633-7","DOIUrl":"10.1007/s00737-025-01633-7","url":null,"abstract":"<div><h3>Background</h3><p>Women’s risk of mental health conditions fluctuates across the lifespan with hormone-mediated reproductive transitions. Reproductive psychiatry, a relatively new subspecialty, focuses on preventing and treating these conditions throughout various reproductive stages. Multimodal large language models (MLLMs) are advanced artificial intelligence (AI) systems that can process and integrate information across multiple modalities, including text, images, audio, and video. Although MLLMs have shown broad utility in healthcare, their potential in reproductive psychiatry remains largely unexplored.Objective: To explore how MLLMs could advance research and clinical care in women’s reproductive mental health and to outline opportunities, requirements, and barriers for safe, equitable deployment.</p><h3>Methods</h3><p>This perspective synthesizes the literature and domain expertise using a consistent analytical framework applied to each application domain in women’s reproductive mental health: (1) define gaps in current clinical knowledge and practice; (2) explain why prevailing AI methods are insufficient; and (3) specify the distinctive advantages of MLLMs, including example data modalities and use cases relevant to reproductive psychiatry.</p><h3>Findings</h3><p>We identify seven application domains: (1) menstruation, (2) pregnancy, (3) abortion, miscarriage and recurrent pregnancy loss, (4) the postpartum period, (5) menopause, (6) psychiatric comorbidities in infertility, and (7) gynecologic conditions (e.g., endometriosis, polycystic ovary syndrome). Across these domains, MLLMs could enable multimodal risk stratification, longitudinal symptom trajectory modelling, clinical decision support, and patient-tailored education and self-management resources that adapt to evolving reproductive stages. Realizing these benefits requires addressing bias in training corpora; safeguarding privacy and consent for sensitive reproductive data; ensuring consistent, high-quality longitudinal data collection across life stages; and establishing standardized, well-governed multimodal repositories specific to women’s health.</p><h3>Conclusions</h3><p>MLLMs hold promise to foster more personalized and precise care in reproductive psychiatry. By mapping opportunities and constraints and proposing a structured evaluation lens, this perspective aims to inform clinicians and researchers, stimulate cross-disciplinary dialogue, and guide responsible development and integration of MLLMs in women’s mental health.</p></div>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"28 6","pages":"1369 - 1384"},"PeriodicalIF":2.7,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00737-025-01633-7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145386420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Partner military deployment during wartime is associated with maternal depression and impaired maternal-infant attachment: a matched-control study from the Israel-Hamas war","authors":"Hadas Allouche-Kam,&nbsp;Sabrina J. Chan,&nbsp;Isha H. Arora,&nbsp;Christina T. Pham,&nbsp;Inbal Reuveni,&nbsp;Eyal Sheiner,&nbsp;Sharon Dekel","doi":"10.1007/s00737-025-01629-3","DOIUrl":"10.1007/s00737-025-01629-3","url":null,"abstract":"<div><h3>Purpose</h3><p>The pregnancy and postpartum periods represent a time of heightened psychological vulnerability with implications for the offspring. Knowledge of the mental health of perinatal women exposed to armed conflict when their partner is in military deployment is scarce.</p><h3>Methods</h3><p>This matched-control, survey-based study included a sample of 429 women recruited during the first months of the Israel-Hamas War who were pregnant or within six months postpartum. Women who had a partner in military deployment were matched primarily on demographics, prior mental health, and trauma exposure to women whose partner was no longer deployed.</p><h3>Results</h3><p>We found that nearly 44% of pregnant women with a partner deployed endorsed probable depression. This group was more than twice as likely to endorse probable depression than matched pregnant controls. Likewise, postpartum women with a partner deployed reported significantly more maternal-infant attachment problems than the matched postpartum group of partners not deployed. Importantly, analysis showed that partner’s active deployment was related to maternal depression and attachment problems via reduced perceived social support.</p><h3>Conclusions</h3><p>Partner military deployment during conditions of war can serve as a major psychological stressor for pregnant and postpartum women. It can heighten psychiatric morbidity and interfere with attachment to the infant in part by diminished social support. Implementation of community-based services for the peripartum population is crucial during times of war and other large-scale traumas.</p></div>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"28 6","pages":"1633 - 1643"},"PeriodicalIF":2.7,"publicationDate":"2025-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145372150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of Tibolone treatment on depression, anxiety and mood in women: a meta-analysis and systematic review of randomized controlled trials","authors":"Li Dong,&nbsp;Yi Gang Wang,&nbsp;Ming Zhang,&nbsp;Mingxing Hu,&nbsp;Qi Yuan,&nbsp;Xi Cheng,&nbsp;Kousalya Prabahar,&nbsp;Guanghai Wang","doi":"10.1007/s00737-025-01615-9","DOIUrl":"10.1007/s00737-025-01615-9","url":null,"abstract":"<div><h3>Background and aim</h3><p>Depression, anxiety, and mood disorders are common in women. Tibolone, acting as both estrogen and progestin, has shown conflicting effects in hormone therapy. This first meta-analysis of RCTs assesses Tibolone’s impact on these conditions in women.</p><h3>Methods</h3><p>Two reviewers independently searched Scopus, PubMed/Medline, Web of Science, and Embase up to 22 May 2024. Using the DerSimonian and Laird random-effects model, weighted mean differences (WMD) with 95% confidence intervals (CI) were calculated. Risk of bias was assessed using the Cochrane tool, and evidence certainty was rated using the GRADE approach.</p><h3>Results</h3><p>Eight articles were included in the meta-analysis. Tibolone significantly reduced depression scores (WMD = -5.335, 95% CI: -9.144 to -1.525, p = 0.006), with high heterogeneity (I² = 99.8%). Greater effects were observed in trials ≤6 months. Anxiety (WMD =-1.489, CI: -3.271 to 0.294, <i>p</i> = 0.102, I² = 99.1%) and mood (WMD = -0.719, CI:-1.805 to 0.366, <i>p</i> = 0.194, I² = 76.6%) scores showed non-significant reductions.</p><h3>Conclusion</h3><p>Tibolone significantly improved depressive symptoms in women, with non-significant trends in anxiety and mood. However, due to high heterogeneity, risk of bias in some studies, and limited number of trials for anxiety and mood outcomes, findings should be interpreted with caution.</p></div>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"28 6","pages":"1357 - 1367"},"PeriodicalIF":2.7,"publicationDate":"2025-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145343142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal and offspring outcomes associated with prescribed ADHD medication in pregnancy: a systematic review","authors":"Sarah Tai,&nbsp;Sohum Patel,&nbsp;Kit Downes,&nbsp;Jonathan Rogers,&nbsp;Hannah Chu-Han Huang","doi":"10.1007/s00737-025-01621-x","DOIUrl":"10.1007/s00737-025-01621-x","url":null,"abstract":"<div><h3>Purpose</h3><p>During pregnancy, it is unclear whether women with attention deficit hyperactivity disorder (ADHD) should stop prescribed medication – risking relapse – or continue – risking harm to themselves and their baby. We aimed to conduct a systematic review to examine whether ADHD medications should be continued during pregnancy.</p><h3>Methods</h3><p>We searched MEDLINE, Embase, PsycINFO, PubMed, CINAHL, AMED, CENTRAL, Cochrane Library, NHS Knowledge and Library Hub from 1st July 2019 to 1st July 2024, without any restrictions on language, setting, or study type. We supplemented this with relevant studies identified from the references of retrieved studies. Two authors used the Newcastle-Ottawa Scale (NOS) to independently rate the quality of included studies.</p><h3>Results</h3><p>Twelve cohort studies were included in the qualitative review. All were deemed high quality (NOS ≥ 7). Seven studies found ADHD medication use during pregnancy had no significant negative effect on maternal or offspring outcomes. One study found continuing ADHD medication reduced the risk of various negative outcomes, and another found stopping ADHD medication may increase the risk of threatened abortion. Three studies concluded that ADHD medication use was associated with negative outcomes: pre-eclampsia, gastroschisis, omphalocele, and transverse limb deficiency. Modafinil was identified as significantly increasing the risk of congenital malformations.</p><h3>Conclusion</h3><p>Women taking modafinil should consider stopping it prior to pregnancy. Clinicians should discuss the risks, benefits, and uncertainties of other ADHD medications with women who are pregnant, or considering pregnancy, keeping in mind that the benefits of continuing ADHD medications- where it is effective for an individual- are likely to outweigh the risks.</p></div>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"28 6","pages":"1425 - 1446"},"PeriodicalIF":2.7,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00737-025-01621-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145285396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perinatal relapse or recurrence rates in women reporting preconception anxiety and/or depression: a longitudinal study using linked data","authors":"Celia Rae,&nbsp;Lucy Leigh,&nbsp;Elizabeth Holliday,&nbsp;Catherine Chojenta","doi":"10.1007/s00737-025-01631-9","DOIUrl":"10.1007/s00737-025-01631-9","url":null,"abstract":"<div><h3>Purpose</h3><p>Few robust estimates of perinatal anxiety and/or depression in women who experienced anxiety and/or depression before pregnancy have been reported in the literature. This study calculated rates of perinatal anxiety and depression in women with a history of the disorders using data from the Australian Longitudinal Study on Women’s Health, the Australian Government’s Pharmaceutical Benefits Scheme and the Medicare Benefits Schedule.</p><h3>Methods</h3><p>The analysis included two cohorts of Australian women. The first comprised 14,247 women born between 1973 and 1978 with nine waves of data collected from 1996 to 2018. The second cohort included 17,010 women born between 1989 and 1995 with data collected from six waves between 2013 and 2019. The proportion of women who reported anxiety and/or depression before having a child and who then reported anxiety and/or depression perinatally (i.e. relapse/recurrence) was calculated for first births and for any birth.</p><h3>Results</h3><p>Compared to women who did not report preconception anxiety or depression, rates of perinatal anxiety and depression were higher among women reporting either condition pre-conceptually. For women in the 1973-78 cohort, the rate of perinatal anxiety was 24% (vs. 7%) and the rate of perinatal depression was 26% (vs. 10%). In the 1989-95 cohort, the rate of perinatal anxiety was 43% for women with preconception anxiety (vs. 18%) and the rate of perinatal depression was 41% for women with preconception depression (vs. 12%).</p><h3>Conclusions</h3><p>Given the high rates of perinatal relapse or recurrence in women with preconception anxiety and/or depression, as well as the well-established risks to the health and development of their offspring, supporting these women to remain asymptomatic during the perinatal period is a priority.</p></div>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"28 6","pages":"1621 - 1631"},"PeriodicalIF":2.7,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00737-025-01631-9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145285383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}