Pub Date : 2025-11-01DOI: 10.1016/j.apjo.2025.100264
Hiu Ying Enne Leung, Lizhen Chen, Sun Li, Mingguang He
{"title":"Embracing the future: A new paradigm for addressing the global myopia epidemic","authors":"Hiu Ying Enne Leung, Lizhen Chen, Sun Li, Mingguang He","doi":"10.1016/j.apjo.2025.100264","DOIUrl":"10.1016/j.apjo.2025.100264","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"14 6","pages":"Article 100264"},"PeriodicalIF":4.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145530316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Barriers to MIGS adoption among glaucoma specialists in India: Insights from a targeted survey","authors":"Sahebaan Sethi, Shweta Tripathi, Maneesh Singh, Nagalekshmi Ganesh, Mayav Movdawalla, Shahinur Tayab","doi":"10.1016/j.apjo.2025.100195","DOIUrl":"10.1016/j.apjo.2025.100195","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"14 6","pages":"Article 100195"},"PeriodicalIF":4.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143794570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01DOI: 10.1016/j.apjo.2025.100204
Saiko Matsumura, Eva K. Fenwick, Momoko Kawakami, Seiji Takagi, Ecosse L. Lamoureux, Yuichi Hori
{"title":"Psychometric evaluation of the Japanese version of the Impact of Vision Impairment (IVI) questionnaire using Rasch analysis","authors":"Saiko Matsumura, Eva K. Fenwick, Momoko Kawakami, Seiji Takagi, Ecosse L. Lamoureux, Yuichi Hori","doi":"10.1016/j.apjo.2025.100204","DOIUrl":"10.1016/j.apjo.2025.100204","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"14 6","pages":"Article 100204"},"PeriodicalIF":4.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01DOI: 10.1016/j.apjo.2025.100262
Robert F. Lam , Nishant V. Radke , Francesco M. Bandello , Pramod Bhende , Yen-Ting Chen , Gemmy C.M. Cheung , Jay Chhablani , Adrian T. Fung , Yi-Ting Hsieh , Chi-Chun Lai , Vincent Y.W. Lee , Xiaorong Li , Tao Li , Jennifer I. Lim , William F. Mieler , Onnisa Nanegrungsunk , Dong Ho Park , Tunde Peto , Rajiv Raman , Paisan Ruamviboonsuk , Dennis S.C. Lam
The management of proliferative diabetic retinopathy (PDR) presents both established consensus and ongoing controversies, particularly regarding emerging therapies (anti-vascular endothelial growth factor agents [VEGF], subthreshold laser and intravitreal steroids) versus conventional approaches (laser photocoagulation and vitrectomy). The Asia-Pacific Vitreo-retina Society (APVRS), the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO) and the Academia Retina Internationalis (ARI) saw such a need to establish consensus and controversial statements on PDR management. They formed an international panel of experts (IPE) comprising 26 experts from 13 countries/territories to establish the statements, including diagnosis and diagnostic technologies, screening approaches, laser, anti-VEGF, intravitreal steroids and vitrectomy and related techniques in PDR management. The objective is to synthesize evidence-based real-world practice recommendations from leading global experts to guide the management of PDR. Of the 37 statements, the IPE reached consensus (75 % voted as “Strong Agreement” or “Agreement”) on 28 (76 %) statements. Controversial statements, such as panretinal photocoagulation (PRP) in special scenarios, use of steroids in cases unresponsive to anti-VEGF and PRP and during vitrectomy to improve visual oucomes, and specific surgical techniques such as internal limiting membrane peeling and drainage retinotomy in the treatment of PDR are identified. Given its high prevalence and propensity for visual morbidity, and the recent advances in surgery for PDR, confirming the standard practices and deliberating on controversies to find the best approach by international experts would help improve the management of PDR further.
{"title":"International consensuses and guidelines on management of proliferative diabetic retinopathy (PDR) by the Asia-Pacific Vitreo-retina Society (APVRS), the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO) and the Academia Retina Internationalis (ARI)","authors":"Robert F. Lam , Nishant V. Radke , Francesco M. Bandello , Pramod Bhende , Yen-Ting Chen , Gemmy C.M. Cheung , Jay Chhablani , Adrian T. Fung , Yi-Ting Hsieh , Chi-Chun Lai , Vincent Y.W. Lee , Xiaorong Li , Tao Li , Jennifer I. Lim , William F. Mieler , Onnisa Nanegrungsunk , Dong Ho Park , Tunde Peto , Rajiv Raman , Paisan Ruamviboonsuk , Dennis S.C. Lam","doi":"10.1016/j.apjo.2025.100262","DOIUrl":"10.1016/j.apjo.2025.100262","url":null,"abstract":"<div><div>The management of proliferative diabetic retinopathy (PDR) presents both established consensus and ongoing controversies, particularly regarding emerging therapies (anti-vascular endothelial growth factor agents [VEGF], subthreshold laser and intravitreal steroids) versus conventional approaches (laser photocoagulation and vitrectomy). The Asia-Pacific Vitreo-retina Society (APVRS), the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO) and the Academia Retina Internationalis (ARI) saw such a need to establish consensus and controversial statements on PDR management. They formed an international panel of experts (IPE) comprising 26 experts from 13 countries/territories to establish the statements, including diagnosis and diagnostic technologies, screening approaches, laser, anti-VEGF, intravitreal steroids and vitrectomy and related techniques in PDR management. The objective is to synthesize evidence-based real-world practice recommendations from leading global experts to guide the management of PDR. Of the 37 statements, the IPE reached consensus (75 % voted as “Strong Agreement” or “Agreement”) on 28 (76 %) statements. Controversial statements, such as panretinal photocoagulation (PRP) in special scenarios, use of steroids in cases unresponsive to anti-VEGF and PRP and during vitrectomy to improve visual oucomes, and specific surgical techniques such as internal limiting membrane peeling and drainage retinotomy in the treatment of PDR are identified. Given its high prevalence and propensity for visual morbidity, and the recent advances in surgery for PDR, confirming the standard practices and deliberating on controversies to find the best approach by international experts would help improve the management of PDR further.</div></div>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"14 6","pages":"Article 100262"},"PeriodicalIF":4.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145480538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01DOI: 10.1016/j.apjo.2025.100219
Yi Li , Xiu Juan Zhang , Yuzhou Zhang , Ka Wai Kam , Alvin L. Young , Patrick Ip , Wei Zhang , Li Jia Chen , Clement C. Tham , Jost B. Jonas , Kyoko Ohno-Matsui , Chi Pui Pang , Jason C. Yam
Purpose
To evaluate longitudinal changes in Bruch’s membrane opening-minimum rim width (BMO-MRW) and its associated factors in school children aged 6–8 years, over 3 years, based on the Hong Kong Children Eye Study.
Methods
In this longitudinal study, 740 children received comprehensive ophthalmologic examinations at baseline and at 3-year follow-up visits. Based on their refractive status, they were divided into groups of persistent non-myopia, newly-developed myopia, and persistent myopia. Global and sectoral BMO-MRW, retinal nerve fiber layer (RNFL) thickness, BMO area, and disc area were all measured using spectral-domain optical coherence tomography (SD-OCT).
Results
The mean age of the participants at baseline was 7.71 ± 1.01 years (range 6–8 years), and 352 (47.7 %) were males. The 3-year follow-up visit revealed a significant increase in all sectors of BMO-MRW, average global BMO-MRW changed from 339.3 ± 51.7 µm to 361.3 ± 57.8 µm. Children in the persistent myopia group and newly developed myopia group showed significantly faster rates of BMO-MRW growth in all sectors compared to children of the persistent non-myopia group (all P < 0.001). In multivariable linear regression analysis, global BMO-MRW enlargement increased with larger axial length elongation (β = 0.20, P< 0.001), larger BMO area enlargement (β = 0.21, P < 0.001), and RNFL thickness thickening (β = 0.45, P < 0.001). It decreased with larger baseline BMO-MRW (β = − 0.17, P < 0.001) and larger disc area enlargement (β = − 0.29, P < 0.001).
Conclusions
Global and sectoral BMO-MRW increased over 3 years among school children aged 6–8 years, affected by larger axial elongation, larger BMO area enlargement, more marked RNFL thickening, and decrease in optic disc area.
目的：基于香港儿童眼科研究，评价6 ~ 8岁学龄儿童布鲁氏膜开口最小边缘宽度（BMO-MRW）的纵向变化及其相关因素。方法：在这项纵向研究中，740名儿童在基线和3年随访时接受了全面的眼科检查。根据患者的屈光状态分为持续非近视组、新发近视组和持续近视组。使用光谱域光学相干断层扫描（SD-OCT）测量全局和局部BMO- mrw、视网膜神经纤维层（RNFL）厚度、BMO面积和椎间盘面积。结果：基线时参与者平均年龄为7.71±1.01岁（6 ~ 8岁），男性352人（47.7%）。3年随访显示各部位BMO-MRW均显著增加，全球平均BMO-MRW从339.3±51.7µm增加到361.3±57.8µm。持续近视组和新发近视组儿童各部位BMO-MRW的增长速率均显著高于持续非近视组儿童（均P < 0.001）。在多变量线性回归分析中，BMO- mrw的整体扩大随着轴向长度延长（β = 0.20, P < 0.001）、BMO面积扩大（β = 0.21, P < 0.001）和RNFL厚度增厚（β = 0.45, P < 0.001）而增加。随着基线BMO-MRW增大（β = -0.17, P < 0.001）和椎间盘面积增大（β = -0.29, P < 0.001），其下降。结论：在6 - 8岁学龄儿童中，整体和局部BMO- mrw在3年内增加，受较大的轴向伸长，较大的BMO面积扩大，更明显的RNFL增厚和视盘面积减少的影响。
{"title":"Longitudinal evaluation of Bruch's membrane opening-minimum rim width in Chinese children: The Hong Kong Children Eye Study","authors":"Yi Li , Xiu Juan Zhang , Yuzhou Zhang , Ka Wai Kam , Alvin L. Young , Patrick Ip , Wei Zhang , Li Jia Chen , Clement C. Tham , Jost B. Jonas , Kyoko Ohno-Matsui , Chi Pui Pang , Jason C. Yam","doi":"10.1016/j.apjo.2025.100219","DOIUrl":"10.1016/j.apjo.2025.100219","url":null,"abstract":"<div><h3>Purpose</h3><div>To evaluate longitudinal changes in Bruch’s membrane opening-minimum rim width (BMO-MRW) and its associated factors in school children aged 6–8 years, over 3 years, based on the Hong Kong Children Eye Study.</div></div><div><h3>Methods</h3><div>In this longitudinal study, 740 children received comprehensive ophthalmologic examinations at baseline and at 3-year follow-up visits. Based on their refractive status, they were divided into groups of persistent non-myopia, newly-developed myopia, and persistent myopia. Global and sectoral BMO-MRW, retinal nerve fiber layer (RNFL) thickness, BMO area, and disc area were all measured using spectral-domain optical coherence tomography (SD-OCT).</div></div><div><h3>Results</h3><div>The mean age of the participants at baseline was 7.71 ± 1.01 years (range 6–8 years), and 352 (47.7 %) were males. The 3-year follow-up visit revealed a significant increase in all sectors of BMO-MRW, average global BMO-MRW changed from 339.3 ± 51.7 µm to 361.3 ± 57.8 µm. Children in the persistent myopia group and newly developed myopia group showed significantly faster rates of BMO-MRW growth in all sectors compared to children of the persistent non-myopia group (all <em>P</em> < 0.001). In multivariable linear regression analysis, global BMO-MRW enlargement increased with larger axial length elongation (β = 0.20, <em>P</em> <em><</em> 0.001), larger BMO area enlargement (β = 0.21, <em>P</em> < 0.001), and RNFL thickness thickening (β = 0.45, <em>P</em> < 0.001). It decreased with larger baseline BMO-MRW (β = − 0.17, <em>P</em> < 0.001) and larger disc area enlargement (β = − 0.29, <em>P</em> < 0.001).</div></div><div><h3>Conclusions</h3><div>Global and sectoral BMO-MRW increased over 3 years among school children aged 6–8 years, affected by larger axial elongation, larger BMO area enlargement, more marked RNFL thickening, and decrease in optic disc area.</div></div>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"14 6","pages":"Article 100219"},"PeriodicalIF":4.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144339869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01DOI: 10.1016/j.apjo.2025.100243
David F. Chang , Wendy See
Purpose
To determine Asia Pacific cataract surgeons’ attitudes toward surgical waste and toward reusing supplies and pharmaceuticals.
Design
Multinational survey of APAO members
Methods
An online survey link was distributed to APAO members through their national ophthalmology societies. Responses were deidentified and compared with those from identical survey questionnaires previously distributed to North American and European cataract surgeons.
Results
Of 2095 total respondents, most were concerned about climate change (94 %), felt cataract surgical waste was excessive (96 %), and felt we should reduce unnecessary waste by safely reusing more surgical supplies and devices (80 %). Most identified manufacturers and regulatory agencies as the biggest drivers of single use products, rather than surgeons and patients. Most surgeons wanted more reusable instruments and supplies (92 %) and wanted greater discretion from manufacturers (92 %) andpolicymakers (90 %) to reuse many supplies, drugs, and devices; 89 % wanted their medical societies to advocate for reducing the waste and carbon footprint of cataract surgery.
Far more APAO respondents (59 %) were currently reusing single-use instruments compared to North Americans (7 %) and Europeans (14 %). Many APAO respondents were currently reusing phacoemulsification tubing/cassettes (41 %), irrigation solution bottles (50 %), and intraocular drug solutions (41–55 %); 42 % were currently not changing surgical gowns between cases. These percentages were all higher compared to North American and European respondents.
Conclusions
These universal and consensus opinions and preferences about willingness to reuse many cataract surgical products should inform and influence pharmaceutical and supply manufacturers, governmental policy makers, and health care institutions, such as hospitals and surgical facilities.
{"title":"APAO survey of cataract surgeons’ attitudes toward operating room waste","authors":"David F. Chang , Wendy See","doi":"10.1016/j.apjo.2025.100243","DOIUrl":"10.1016/j.apjo.2025.100243","url":null,"abstract":"<div><h3>Purpose</h3><div>To determine Asia Pacific cataract surgeons’ attitudes toward surgical waste and toward reusing supplies and pharmaceuticals.</div></div><div><h3>Design</h3><div>Multinational survey of APAO members</div></div><div><h3>Methods</h3><div>An online survey link was distributed to APAO members through their national ophthalmology societies. Responses were deidentified and compared with those from identical survey questionnaires previously distributed to North American and European cataract surgeons.</div></div><div><h3>Results</h3><div>Of 2095 total respondents, most were concerned about climate change (94 %), felt cataract surgical waste was excessive (96 %), and felt we should reduce unnecessary waste by safely reusing more surgical supplies and devices (80 %). Most identified manufacturers and regulatory agencies as the biggest drivers of single use products, rather than surgeons and patients. Most surgeons wanted more reusable instruments and supplies (92 %) and wanted greater discretion from manufacturers (92 %) andpolicymakers (90 %) to reuse many supplies, drugs, and devices; 89 % wanted their medical societies to advocate for reducing the waste and carbon footprint of cataract surgery.</div><div>Far more APAO respondents (59 %) were currently reusing single-use instruments compared to North Americans (7 %) and Europeans (14 %). Many APAO respondents were currently reusing phacoemulsification tubing/cassettes (41 %), irrigation solution bottles (50 %), and intraocular drug solutions (41–55 %); 42 % were currently not changing surgical gowns between cases. These percentages were all higher compared to North American and European respondents.</div></div><div><h3>Conclusions</h3><div>These universal and consensus opinions and preferences about willingness to reuse many cataract surgical products should inform and influence pharmaceutical and supply manufacturers, governmental policy makers, and health care institutions, such as hospitals and surgical facilities.</div></div>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"14 6","pages":"Article 100243"},"PeriodicalIF":4.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145013771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enhanced visualization and removal of epithelial ingrowth after SMILE and LASIK using a fiberoptic illuminator","authors":"Yi-Ting Hou , Le-Yu Chen , I-Hung Lin , Wei-Li Chen","doi":"10.1016/j.apjo.2025.100172","DOIUrl":"10.1016/j.apjo.2025.100172","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"14 6","pages":"Article 100172"},"PeriodicalIF":4.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143584419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01DOI: 10.1016/j.apjo.2025.100209
Ebenezer Zaabaar , Yuzhou Zhang , Ka Wai Kam , Yingan Li , Xiu Juan Zhang , Mary Ho , Dong Liu , Mandy PH Ng , Patrick Ip , Alvin Young , Chi Pui Pang , Clement C. Tham , Mei-Po Kwan , Li Jia Chen , Jason C. Yam
Purpose
To investigate the association of joint exposure to residential air pollutants with different severities of visual impairment (VI) in adults.
Methods
Exposure to particulate matter and oxides of nitrogen were evaluated in 95,246 adults aged 40–70 years. Joint exposure to the pollutants was calculated using principal component analysis to create an air pollution score. Subjects were categorized by distance visual acuity into bilateral normal vision, near normal vision, unilateral VI, socially significant VI, and blindness and low vision.
Results
A unit rise in air pollution score was associated with 9.2 %, 4.1 %, and 1.8 % increased risks of blindness and low vision, adjusted OR (AOR) = 1.092 (95 % CI, 1.057–1.129); socially significant VI, AOR = 1.041 (95 % CI, 1.016–1.066); and unilateral VI, AOR = 1.018 (95 % CI, 1.007–1.029), respectively. Compared to subjects in the lowest quartile of air pollution score, those in the highest quartile had 69.2 %, 30.5 %, and 9.9 % greater risks of blindness and low vision, AOR = 1.692 (95 % CI, 1.355–2.114), socially significant VI, AOR = 1.305 (95 % CI, 1.127–1.513), and unilateral VI, AOR = 1.099 (95 % CI, 1.035–1.167), respectively while those in the third quartile had 40.5 % and 25.6 % higher risks of blindness and low vision, AOR = 1.405 (95 % CI, 1.121–1.760) and socially significant VI, AOR = 1.256 (95 % CI, 1.086–1.453), respectively. There was a significant trend of increasing risk of blindness and low vision, as well as socially significant VI, as pollution levels rose.
Conclusion
Joint exposure to air pollutants increased the risks of poor vision and blindness, suggesting that reducing such exposure could alleviate the disease burden of VI.
{"title":"Association of residential air pollution with visual impairment in adults: The UK Biobank study","authors":"Ebenezer Zaabaar , Yuzhou Zhang , Ka Wai Kam , Yingan Li , Xiu Juan Zhang , Mary Ho , Dong Liu , Mandy PH Ng , Patrick Ip , Alvin Young , Chi Pui Pang , Clement C. Tham , Mei-Po Kwan , Li Jia Chen , Jason C. Yam","doi":"10.1016/j.apjo.2025.100209","DOIUrl":"10.1016/j.apjo.2025.100209","url":null,"abstract":"<div><h3>Purpose</h3><div>To investigate the association of joint exposure to residential air pollutants with different severities of visual impairment (VI) in adults.</div></div><div><h3>Methods</h3><div>Exposure to particulate matter and oxides of nitrogen were evaluated in 95,246 adults aged 40–70 years. Joint exposure to the pollutants was calculated using principal component analysis to create an air pollution score. Subjects were categorized by distance visual acuity into bilateral normal vision, near normal vision, unilateral VI, socially significant VI, and blindness and low vision.</div></div><div><h3>Results</h3><div>A unit rise in air pollution score was associated with 9.2 %, 4.1 %, and 1.8 % increased risks of blindness and low vision, adjusted OR (AOR) = 1.092 (95 % CI, 1.057–1.129); socially significant VI, AOR = 1.041 (95 % CI, 1.016–1.066); and unilateral VI, AOR = 1.018 (95 % CI, 1.007–1.029), respectively. Compared to subjects in the lowest quartile of air pollution score, those in the highest quartile had 69.2 %, 30.5 %, and 9.9 % greater risks of blindness and low vision, AOR = 1.692 (95 % CI, 1.355–2.114), socially significant VI, AOR = 1.305 (95 % CI, 1.127–1.513), and unilateral VI, AOR = 1.099 (95 % CI, 1.035–1.167), respectively while those in the third quartile had 40.5 % and 25.6 % higher risks of blindness and low vision, AOR = 1.405 (95 % CI, 1.121–1.760) and socially significant VI, AOR = 1.256 (95 % CI, 1.086–1.453), respectively. There was a significant trend of increasing risk of blindness and low vision, as well as socially significant VI, as pollution levels rose.</div></div><div><h3>Conclusion</h3><div>Joint exposure to air pollutants increased the risks of poor vision and blindness, suggesting that reducing such exposure could alleviate the disease burden of VI.</div></div>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"14 6","pages":"Article 100209"},"PeriodicalIF":4.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144131845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01DOI: 10.1016/j.apjo.2025.100166
Fengbin Lin , Liu Li , Ping Lu , Li Tang , Yao Zhang , Lin Xie , Xiaomin Zhu , Guangxian Tang , Hengli Zhang , Lan Lu , Meichun Xiao , Jiangang Xu , Yunhe Song , Yuying Peng , Xiaoyan Li , Weirong Chen , Fengqi Zhou , Ningli Wang , Keith Barton , Ki Ho Park , Xiulan Zhang
Purpose
To evaluate the two-year outcomes of combined surgical peripheral iridectomy (SPI), goniosynechialysis (GSL), and goniotomy (GT) for advanced primary angle-closure glaucoma (PACG) without cataract.
Design
Multicenter prospective study.
Methods
The study included patients who received a combined SPI + GSL + GT for advanced PACG without cataract, all completed a 24-month follow-up. Outcome measures included changes in intraocular pressure (IOP), best-corrected visual acuity (BCVA), use of anti-glaucoma medications, surgical success, and postoperative complications over the 24-month period.
Results
A total of 63 eyes from 51 patients with advanced PACG were included in the study. Among these, 37 eyes (58.7 %) achieved complete success, and 55 eyes (87.3 %) achieved qualified success. The mean IOPs at baseline and after 24 months were 28.8 ± 7.51 mm Hg and 15.8 ± 4.40 mm Hg, respectively (P < 0.001). The average number of anti-glaucoma medications decreased from 1.9 ± 1.4–0.8 ± 1.2 over the 24-month period (P < 0.001). The overall BCVA was stable during the follow-up period (P = 0.225). The primary complications observed included IOP spike (n = 9), hyphema (n = 7), and shallow anterior chamber (n = 3), all of which occurred within the first month postoperatively. Regression analysis showed that older age was positively associated with both complete success [odds ratio (OR) = 1.05; P = 0.030] and qualified success (OR = 1.08; P = 0.024).
Conclusions
SPI + GSL + GT demonstrated safety and effectiveness in treating advanced PACG without cataract over the 24-month study period. This combined surgical approach should be considered a viable alternative to trabeculectomy for these patients.
{"title":"Two-year outcomes of combined surgical peripheral iridectomy, goniosynechialysis, and goniotomy for advanced primary angle-closure glaucoma without cataract: A multicenter study","authors":"Fengbin Lin , Liu Li , Ping Lu , Li Tang , Yao Zhang , Lin Xie , Xiaomin Zhu , Guangxian Tang , Hengli Zhang , Lan Lu , Meichun Xiao , Jiangang Xu , Yunhe Song , Yuying Peng , Xiaoyan Li , Weirong Chen , Fengqi Zhou , Ningli Wang , Keith Barton , Ki Ho Park , Xiulan Zhang","doi":"10.1016/j.apjo.2025.100166","DOIUrl":"10.1016/j.apjo.2025.100166","url":null,"abstract":"<div><h3>Purpose</h3><div>To evaluate the two-year outcomes of combined surgical peripheral iridectomy (SPI), goniosynechialysis (GSL), and goniotomy (GT) for advanced primary angle-closure glaucoma (PACG) without cataract.</div></div><div><h3>Design</h3><div>Multicenter prospective study.</div></div><div><h3>Methods</h3><div>The study included patients who received a combined SPI + GSL + GT for advanced PACG without cataract, all completed a 24-month follow-up. Outcome measures included changes in intraocular pressure (IOP), best-corrected visual acuity (BCVA), use of anti-glaucoma medications, surgical success, and postoperative complications over the 24-month period.</div></div><div><h3>Results</h3><div>A total of 63 eyes from 51 patients with advanced PACG were included in the study. Among these, 37 eyes (58.7 %) achieved complete success, and 55 eyes (87.3 %) achieved qualified success. The mean IOPs at baseline and after 24 months were 28.8 ± 7.51 mm Hg and 15.8 ± 4.40 mm Hg, respectively (P < 0.001). The average number of anti-glaucoma medications decreased from 1.9 ± 1.4–0.8 ± 1.2 over the 24-month period (P < 0.001). The overall BCVA was stable during the follow-up period (P = 0.225). The primary complications observed included IOP spike (n = 9), hyphema (n = 7), and shallow anterior chamber (n = 3), all of which occurred within the first month postoperatively. Regression analysis showed that older age was positively associated with both complete success [odds ratio (OR) = 1.05; P = 0.030] and qualified success (OR = 1.08; P = 0.024).</div></div><div><h3>Conclusions</h3><div>SPI + GSL + GT demonstrated safety and effectiveness in treating advanced PACG without cataract over the 24-month study period. This combined surgical approach should be considered a viable alternative to trabeculectomy for these patients.</div></div>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":"14 6","pages":"Article 100166"},"PeriodicalIF":4.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143530995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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