Asia-Pacific Journal of Ophthalmology最新文献

{"title":"Comment on “Central retinal artery occlusion in rhino-orbital-cerebral mucormycosis: An inflammatory-prothrombotic state”","authors":"Damir Bosnar, Mira Knežić Zagorec, Mladen Bušić","doi":"10.1097/APO.0000000000000615","DOIUrl":"10.1097/APO.0000000000000615","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S216209892400029X/pdfft?md5=ba138172c15748eb3fe0907dcabfc27b&pid=1-s2.0-S216209892400029X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10168914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Natural Course for Retinal Detachment in Morning Glory Disc Anomaly Based on a Grading System","authors":"Yihua Zou, Xiaohan Wang, Jing Li, Jie Peng, Peiquan Zhao","doi":"10.1097/APO.0000000000000572","DOIUrl":"10.1097/APO.0000000000000572","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2162098924000240/pdfft?md5=6993f4df65288d3737863ee060979ae2&pid=1-s2.0-S2162098924000240-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139490775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous Regression and Recurrence of Corneal Intrastromal Cyst","authors":"Mona Bhargava, Raj S. Paul, Karan R. Nathani","doi":"10.1097/APO.0000000000000575","DOIUrl":"10.1097/APO.0000000000000575","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2162098924000203/pdfft?md5=dd014a4d85dfa496be2c6d5425b63400&pid=1-s2.0-S2162098924000203-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10632191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interocular difference in crystalline lens morphology in children and adolescents with unilateral high myopia","authors":"Yifan Zhang ,&nbsp;Jiaqing Zhang ,&nbsp;Aixia Jin ,&nbsp;Xuhua Tan ,&nbsp;Kyoko Ohno-Matsui ,&nbsp;Xiaotong Han ,&nbsp;Lixia Luo ,&nbsp;Yizhi Liu","doi":"10.1016/j.apjo.2023.100001","DOIUrl":"https://doi.org/10.1016/j.apjo.2023.100001","url":null,"abstract":"<div><h3>Purpose</h3><p>To investigate the between-eye differences of the crystalline lens in subjects with unilateral high myopia and assess its contribution to the interocular refractive error disparity.</p></div><div><h3>Methods</h3><p>Children and adolescents with unilateral high myopia, defined as cycloplegic spherical equivalent (SE) ≤ −5D in one eye and ≥ −3D in the other eye, were recruited. Ocular biometric parameters, including axial length (AL) and lens thickness (LT), were measured by IOLMaster 700. Other lens-related parameters, including anterior lens radius of curvature (ALR) and posterior lens radius of curvature (PLR), were measured by CASIA2 swept-source optical coherence tomography. Lens power (LP) was calculated using Bennett’s formula. Paired t-test was used to assess the between-eye difference in biometric parameters, and multiple regression analysis was used to assess factors associated with the between-eye SE difference.</p></div><div><h3>Results</h3><p>Ninety-one participants (6–18 years of age; 52.75% girls) were included. The highly myopic eyes showed significantly lower LP (P &lt; 0.001) and smaller ALR (P &lt; 0.001) than the contralateral eyes, while no significant difference was found in central LT. In both eyes, ALR was significantly related to SE (P = 0.001 and P = 0.006, respectively); while LT was not associated with SE (P = 0.051 and P = 0.052, respectively). Paired-eye analysis showed that the between-eye difference in ALR was the only lenticular parameter significantly associated with the between-eye difference in SE (P = 0.005).</p></div><div><h3>Conclusion</h3><p>In highly myopic eyes, the crystalline lens reduced total power but morphologically changed to a more curved shape without significant lens thinning, suggesting that the LP loss is mainly achieved by reducing its internal power in high myopes.</p></div>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2162098923000014/pdfft?md5=65c931b380df1f0898914ad88665a4bb&pid=1-s2.0-S2162098923000014-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139901548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genetic associations of central serous chorioretinopathy subtypes, neovascular age-related macular degeneration, and polypoidal choroidal vasculopathy","authors":"Zhen Ji Chen ,&nbsp;Danny S. Ng ,&nbsp;Mary Ho ,&nbsp;Shi Yao Lu ,&nbsp;Pancy O.S. Tam ,&nbsp;Alvin L. Young ,&nbsp;Marten E. Brelen ,&nbsp;Jason C. Yam ,&nbsp;Clement C. Tham ,&nbsp;Chi Pui Pang ,&nbsp;Li Jia Chen","doi":"10.1016/j.apjo.2023.100003","DOIUrl":"https://doi.org/10.1016/j.apjo.2023.100003","url":null,"abstract":"<div><h3>Purpose</h3><p>To evaluate the genetic associations of different subtypes of central serous chorioretinopathy (CSCR), neovascular age-related macular degeneration (nAMD), and polypoidal choroidal vasculopathy (PCV).</p></div><div><h3>Design</h3><p>A case-control genetic association study.</p></div><div><h3>Methods</h3><p>This study enrolled 217 CSCR, 341 nAMD, 288 PCV patients, and 1380 controls. The CSCR patients were classified into those with focal or diffuse leakage, with or without pigment epithelial detachment (PED), and with or without macular neovascularization (MNV). Associations between 11 variants from 8 genes, <em>ADAMTS9</em>, <em>ANGPT2</em>, <em>ARMS2</em>, <em>CFH</em>, <em>NR3C2</em>, <em>PGF</em>, <em>TNFRSF10A</em> and <em>VIPR2</em>, and diseases/subtypes were analyzed by logistic regression analysis adjusted for age and sex, and inter-phenotype comparison by heterogeneity test.</p></div><div><h3>Results</h3><p>The <em>CFH</em> rs800292-A conferred a protective effect for CSCR with MNV (OR=0.44, <em>P</em> = 0.002) and a risk effect for CSCR without MNV (OR=1.31, <em>P</em> = 0.023). CSCR patients carrying rs800292-G had a 3.23-fold of increased risk towards developing secondary MNV (<em>P</em> = 1.45 ×10^-4). <em>CFH</em> rs3753394, rs800292 and rs1329428 showed similar effects among CSCR with MNV, nAMD and PCV, but opposite effects on CSCR without MNV. <em>TNFRSF10A</em> rs13278062-T was associated with overall CSCR but not with CSCR subtypes, nAMD or PCV. Moreover, <em>CFH</em> and <em>ARMS2</em> SNPs showed heterogeneous effects in CSCR without MNV against CSCR with MNV, nAMD and PCV.</p></div><div><h3>Conclusions</h3><p>Genetic associations of CSCR with MNV resembled nAMD and PCV compared to CSCR without MNV, indicating differential genetic effects on neovascularization and choroidopathy. Further investigation of the functional roles of <em>CFH, ARMS2,</em> and <em>TNFRSF10A</em> in CSCR, nAMD and PCV should help elucidate the mechanisms of these maculopathies.</p></div>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2162098923000038/pdfft?md5=e4f3cb82f59b58007c5c6fba34daf66b&pid=1-s2.0-S2162098923000038-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139901549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Central retinal artery occlusion in rhino-orbital-cerebral mucormycosis: An inflammatory-prothrombotic state\".","authors":"Damir Bosnar, Mira Knežić Zagorec, Mladen Bušić","doi":"10.1097/APO.0000000000000615","DOIUrl":"10.1097/APO.0000000000000615","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139705949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integration of Massive Open Online Course (MOOC) in Ophthalmic Skills Training for Medical Students: Outcomes and Perspectives","authors":"Sasha Zaki","doi":"10.1097/APO.0000000000000601","DOIUrl":"10.1097/APO.0000000000000601","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2162098924000227/pdfft?md5=e1d477e95255ff88036144384947c598&pid=1-s2.0-S2162098924000227-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9287461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rationale and protocol paper for the Asia Pacific Network for inherited eye diseases","authors":"Wendy M. Wong ,&nbsp;Yih Chung Tham ,&nbsp;Matthew P. Simunovic ,&nbsp;Fred Kuanfu Chen ,&nbsp;Chi D. Luu ,&nbsp;Haoyu Chen ,&nbsp;Zi-Bing Jin ,&nbsp;Ren-Juan Shen ,&nbsp;Shiying Li ,&nbsp;Ruifang Sui ,&nbsp;Chen Zhao ,&nbsp;Liping Yang ,&nbsp;Muna Bhende ,&nbsp;Rajiv Raman ,&nbsp;Parveen Sen ,&nbsp;Arkasubhra Ghosh ,&nbsp;B. Poornachandra ,&nbsp;Muhammad Bayu Sasongko ,&nbsp;Alia Arianti ,&nbsp;Valen Chia ,&nbsp;Hwei Wuen Chan","doi":"10.1016/j.apjo.2023.100030","DOIUrl":"10.1016/j.apjo.2023.100030","url":null,"abstract":"<div><h3>Purpose</h3><p>There are major gaps in our knowledge of hereditary ocular conditions in the Asia-Pacific population, which comprises approximately 60% of the world's population. Therefore, a concerted regional effort is urgently needed to close this critical knowledge gap and apply precision medicine technology to improve the quality of lives of these patients in the Asia-Pacific region.</p></div><div><h3>Design</h3><p>Multi-national, multi-center collaborative network.</p></div><div><h3>Methods</h3><p>The Research Standing Committee of the Asia-Pacific Academy of Ophthalmology and the Asia-Pacific Society of Eye Genetics fostered this research collaboration, which brings together renowned institutions and experts for inherited eye diseases in the Asia-Pacific region. The immediate priority of the network will be inherited retinal diseases (IRDs), where there is a lack of detailed characterization of these conditions and in the number of established registries.</p></div><div><h3>Results</h3><p>The network comprises 55 members from 35 centers, spanning 12 countries and regions, including Australia, China, India, Indonesia, Japan, South Korea, Malaysia, Nepal, Philippines, Singapore, Taiwan, and Thailand. The steering committee comprises ophthalmologists with experience in consortia for eye diseases in the Asia-Pacific region, leading ophthalmologists and vision scientists in the field of IRDs internationally, and ophthalmic geneticists.</p></div><div><h3>Conclusions</h3><p>The Asia Pacific Inherited Eye Disease (APIED) network aims to (1) improve genotyping capabilities and expertise to increase early and accurate genetic diagnosis of IRDs, (2) harmonise deep phenotyping practices and utilization of ontological terms, and (3) establish high-quality, multi-user, federated disease registries that will facilitate patient care, genetic counseling, and research of IRDs regionally and internationally.</p></div>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2162098923000300/pdfft?md5=e6c9bf41d8332b424fdfd963f3895da3&pid=1-s2.0-S2162098923000300-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139485064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phacogoniotomy: An alternative treatment for advanced primary angle-closure glaucoma with cataract","authors":"Poemen P.M. Chan,&nbsp;Enne Hiu Ying Leung,&nbsp;Jost B. Jonas,&nbsp;Dennis S.C. Lam","doi":"10.1016/j.apjo.2024.100034","DOIUrl":"10.1016/j.apjo.2024.100034","url":null,"abstract":"","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S216209892400001X/pdfft?md5=de4fe09c0f8680455153030cf09e5b23&pid=1-s2.0-S216209892400001X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139566399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative intense pulsed light to prevent and improve symptoms of post-laser corneal refractive surgery dry eye. A randomized clinical trial","authors":"María C. Martínez-Hergueta ,&nbsp;Mario Cantó-Cerdán ,&nbsp;Maria A. Amesty ,&nbsp;M. Jose García-Corral ,&nbsp;Laura Casanova-Blanquer ,&nbsp;Ana B. Plaza-Puche ,&nbsp;Jorge L. Alió ,&nbsp;Jorge L. Alió del Barrio","doi":"10.1016/j.apjo.2023.100029","DOIUrl":"https://doi.org/10.1016/j.apjo.2023.100029","url":null,"abstract":"<div><h3>Purpose</h3><p>To evaluate the efficacy of perioperative IPL therapy in preventing postoperative ocular surface disorders in patients undergoing corneal laser refractive surgery.</p></div><div><h3>Design</h3><p>randomized, controlled, clinical trial with triple-blinding.</p></div><div><h3>Methods</h3><p><em>Setting</em>: Vissum Miranza - Alicante; <em>Study population</em>: 61 patients randomized in two groups: 31 study patients (perioperative IPL + laser refractive surgery) and 30 control patients (perioperative placebo + laser refractive surgery). Follow-up was conducted over a 6-month period; <em>Intervention:</em> Each participants underwent three IPL sessions with a two-week interval between each session (pre-surgery, post-surgery week-one, and post-surgery week-three). For controls, placebo was administered following the same protocol. <em>Main outcomes measures</em>: visual outcomes and refraction, slit-lamp examination, corneal topography, visual analogue scale questionnaire and Oculus Keratograph 5 M including tear meniscus height, non-invasive tear break- up time, ocular redness, infrared meibography and Ocular Surface Disease Index (OSDI) questionnaire.</p></div><div><h3>Results</h3><p>61 randomized eyes were included. No significant differences were observed in terms of uncorrected and corrected distance visual acuity (UDVA, CDVA), refractive error or corneal aberrations. A statistically significant improvement in OSDI score (change −8.47, p = 0.043), tear meniscus (change 0.05 mm, p = 0.004) and Meibography (change −0.42, p = 0.012) was observed at the third postoperative month in the study group. Additionally, at the sixth postoperative month, there were statistically significant improvements in tear meniscus (change 0.06 mm, p = 0.018), tear break-up-time (change 1.68 s, p = 0.039) and Meibography (change −0.37, p = 0.030).</p></div><div><h3>Conclusions</h3><p>Results suggest that perioperative IPL therapy applied to laser corneal refractive surgery improves objective and subjective ocular surface parameters over non-IPL-treated control patients and early postoperative dry eye symptoms.</p></div>","PeriodicalId":8594,"journal":{"name":"Asia-Pacific Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2162098923000294/pdfft?md5=1085007efef0299aa01c2f92ff7a82ae&pid=1-s2.0-S2162098923000294-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139901563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}