Pub Date : 2023-06-16DOI: 10.3329/bjms.v22i3.65320
A. Nurudhin, N. Prabowo, Yulyani Werdiningsih, Fatichati Budiningsih, Tiara Maharani, Agung Karyawinara, R. Widyastuti
Background: Snail mucus (Achatina Fulica) has been known to contain heparan sulfate, and acharan sulfate, a glycosaminoglycan with anti-inflammatory properties and might repair the injured glomeruli. Aim: This study aims to find the effect of snail mucus on activity and chronicity indices of renal histology in a pristane-induced lupus nephritis mice model. Method: This was an experimental study with a post-test-only control group design using 42 mice strains Balb/C. Mice were randomized into six groups: control, lupus nephritis, methylprednisolone, snail mucus 0.5 ccs, snail mucus 0,5 cc and methylprednisolone, and snail mucus one cc and methylprednisolone group. Result: Snail mucus significantly affected the activity index (p = 0.001). The lowest activity index was shown by snail mucus one cc and methylprednisolone group. While the chronicity index was not significantly affected by the snail mucus with p = 0.195. Snail mucus decreases the activity index of renal histology in the pristane-induced lupus nephritis mice model but not the chronicity index. Bangladesh Journal of Medical Science Vol. 22 No. 03 July’23 Page : 515-520
{"title":"The Effect of Snail Mucus (Achatina Fulica) Toward The Activity and Chronicity Indices of Renal Histology in Pristane-Induced Lupus Nephritis Mice Model","authors":"A. Nurudhin, N. Prabowo, Yulyani Werdiningsih, Fatichati Budiningsih, Tiara Maharani, Agung Karyawinara, R. Widyastuti","doi":"10.3329/bjms.v22i3.65320","DOIUrl":"https://doi.org/10.3329/bjms.v22i3.65320","url":null,"abstract":"Background: Snail mucus (Achatina Fulica) has been known to contain heparan sulfate, and acharan sulfate, a glycosaminoglycan with anti-inflammatory properties and might repair the injured glomeruli.\u0000Aim: This study aims to find the effect of snail mucus on activity and chronicity indices of renal histology in a pristane-induced lupus nephritis mice model.\u0000Method: This was an experimental study with a post-test-only control group design using 42 mice strains Balb/C. Mice were randomized into six groups: control, lupus nephritis, methylprednisolone, snail mucus 0.5 ccs, snail mucus 0,5 cc and methylprednisolone, and snail mucus one cc and methylprednisolone group.\u0000Result: Snail mucus significantly affected the activity index (p = 0.001). The lowest activity index was shown by snail mucus one cc and methylprednisolone group. While the chronicity index was not significantly affected by the snail mucus with p = 0.195. Snail mucus decreases the activity index of renal histology in the pristane-induced lupus nephritis mice model but not the chronicity index.\u0000Bangladesh Journal of Medical Science Vol. 22 No. 03 July’23 Page : 515-520","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"79 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76120594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-16DOI: 10.3329/bjms.v22i3.66958
Rahnuma Ahmad, Mainul Haque
Abstract not available Bangladesh Journal of Medical Science Vol. 22 No. 03 July’23 Page : 465-471
《孟加拉国医学科学杂志》第22卷第23年7月3日第465-471页
{"title":"Obesity: A Burden Borne by the Global Economy","authors":"Rahnuma Ahmad, Mainul Haque","doi":"10.3329/bjms.v22i3.66958","DOIUrl":"https://doi.org/10.3329/bjms.v22i3.66958","url":null,"abstract":"Abstract not available \u0000Bangladesh Journal of Medical Science Vol. 22 No. 03 July’23 Page : 465-471","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"74 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78734779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-16DOI: 10.3329/bjms.v22i3.65331
Faseeha Eram, M. A. Quamri, Muzafar Din Ahmad Bhat, U. Siddiqui, Sumbul Nida
Background: Ischemic heart disease (IHD) also known as coronary artery disease (CAD) is the leading cause of death worldwide. IHD is caused by obstruction of one or more coronary arteries. Among the various causes of obstruction atherosclerosis is the leading cause. Physical inactivity, smoking, saturated fat rich diet, hypertension, diabetes mellitus, dyslipidaemia are modifiable risk factors for atherosclerosis which ultimately results in IHD. In this article we will discuss the disease in the light of Unani system of Medicine and how to manage it depending on the understood concepts Methods: A number of classical Unani textbooks were referred for description of various heart diseases and various search engines such as PubMed, Google Scholar and Research Gate were cited for recent advancements using the key words IHD, atherosclerosis, cardio-protective herbal drugs, etc. Conclusion: Owing to the irreversible damage due to IHD it is better to prevent myocardium damage by minimising the risk factors at its earliest. In Unani system of medicine many cardio-protective drugs have been described which when combined with lifestyle modification can play vital role in keeping cardiac diseases at bay. Bangladesh Journal of Medical Science Vol. 22 No. 03 July’23 Page : 475-481
背景:缺血性心脏病(IHD)也被称为冠状动脉疾病(CAD)是世界范围内死亡的主要原因。IHD是由一个或多个冠状动脉阻塞引起的。在各种阻塞原因中，动脉粥样硬化是首要原因。缺乏运动、吸烟、富含饱和脂肪的饮食、高血压、糖尿病、血脂异常是动脉粥样硬化的可改变危险因素，最终导致IHD。在本文中，我们将在Unani医学体系的基础上讨论这种疾病，以及如何根据所理解的概念来管理它。方法:参考一些经典的Unani教科书来描述各种心脏病，并引用PubMed, Google Scholar和Research Gate等各种搜索引擎，以IHD，动脉粥样硬化，心脏保护草药等为关键词引用最近的进展。由于IHD具有不可逆的损伤，因此尽早减少危险因素是预防心肌损伤的最好方法。在Unani医学系统中，许多心脏保护药物已经被描述，当与生活方式的改变相结合时，可以在保持心脏病的海湾中发挥重要作用。《孟加拉国医学科学杂志》第22卷第23年7月3日第475-481页
{"title":"“Perspective of Ischemic Heart Disease (Iqfari Marad-i-Qalb) with reference to Unani Medicine”","authors":"Faseeha Eram, M. A. Quamri, Muzafar Din Ahmad Bhat, U. Siddiqui, Sumbul Nida","doi":"10.3329/bjms.v22i3.65331","DOIUrl":"https://doi.org/10.3329/bjms.v22i3.65331","url":null,"abstract":"Background: Ischemic heart disease (IHD) also known as coronary artery disease (CAD) is the leading cause of death worldwide. IHD is caused by obstruction of one or more coronary arteries. Among the various causes of obstruction atherosclerosis is the leading cause. Physical inactivity, smoking, saturated fat rich diet, hypertension, diabetes mellitus, dyslipidaemia are modifiable risk factors for atherosclerosis which ultimately results in IHD. In this article we will discuss the disease in the light of Unani system of Medicine and how to manage it depending on the understood concepts\u0000Methods: A number of classical Unani textbooks were referred for description of various heart diseases and various search engines such as PubMed, Google Scholar and Research Gate were cited for recent advancements using the key words IHD, atherosclerosis, cardio-protective herbal drugs, etc.\u0000Conclusion: Owing to the irreversible damage due to IHD it is better to prevent myocardium damage by minimising the risk factors at its earliest. In Unani system of medicine many cardio-protective drugs have been described which when combined with lifestyle modification can play vital role in keeping cardiac diseases at bay.\u0000Bangladesh Journal of Medical Science Vol. 22 No. 03 July’23 Page : 475-481","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"105 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76693670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-16DOI: 10.3329/bjms.v22i3.65339
Somia Gul, Aisha Aziz, Afsa Jilani
Background: Trypophobia is a psychological fear and has been described as a phobia to images with high-contrast energy at low and midrange spatial frequencies, such as holes and repetitive patterns. Method: This randomized study was conducted from September 2016 to March 2017 (n=214) through online surveys, visiting various university departments, interviewing common laymen and individuals from dissimilar families to approach maximum number of participants with less biasness. This was a useful survey for assessing the level of awareness and number of causalities in Pakistani population. Result: Results of current study show that there were few individuals diagnosed with trypophobia and were trying to get rid of it. Other individuals were either unknown or confused about this fear. Conclusion: We conclude that this study is beneficial for assessing presence of trypophobic fear in Pakistani population. Bangladesh Journal of Medical Science Vol. 22 No. 03 July’23 Page : 638-642
{"title":"Trypophobia an Unrevealed Truth: A Glance of Its Awareness and Prevalence in General Population of Pakistan","authors":"Somia Gul, Aisha Aziz, Afsa Jilani","doi":"10.3329/bjms.v22i3.65339","DOIUrl":"https://doi.org/10.3329/bjms.v22i3.65339","url":null,"abstract":"Background: Trypophobia is a psychological fear and has been described as a phobia to images with high-contrast energy at low and midrange spatial frequencies, such as holes and repetitive patterns.\u0000Method: This randomized study was conducted from September 2016 to March 2017 (n=214) through online surveys, visiting various university departments, interviewing common laymen and individuals from dissimilar families to approach maximum number of participants with less biasness. This was a useful survey for assessing the level of awareness and number of causalities in Pakistani population.\u0000Result: Results of current study show that there were few individuals diagnosed with trypophobia and were trying to get rid of it. Other individuals were either unknown or confused about this fear.\u0000Conclusion: We conclude that this study is beneficial for assessing presence of trypophobic fear in Pakistani population.\u0000Bangladesh Journal of Medical Science Vol. 22 No. 03 July’23 Page : 638-642","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"114 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80794958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-21DOI: 10.3329/bjms.v22i20.66316
P. Kukreja, B. Kukreja, K. Bhat
Introduction: Inflammation of the supporting tissues which is also known as periodontitis contributes to the major etiological factor for tooth loss. Consortium of pathogenic bacteria with elevated levels lead to onset and progression of periodontal disease. Gram negative bacteria, primarily severe anaerobes, are responsible for most of it. Aims and Objectives: The present study aimed to assess the presence of Treponema denticola in periodontal disease in different subgingival plaque samples collected from the oral cavity of 30 patients diagnosed with chronic periodontitis. The plaque samples were compared with similar plaque samples of 15 healthy patients. Method: Subgingival dental plaque samples from shallow and deep crevices were examined for the presence of bacterial DNA using the PCR method, which enables the simultaneous identification of multiple bacterial genomes. Results: PCR results show amplification and quantification of T. denticola in 10 out of 15 patients in group-1, 9 out of 15 patients in group-2, and 4 out of 15 patients in group-3. The statistical analyses of the results show that they are statistically significant. Conclusion: According to the aforementioned study, PCR microorganism identification is sensitive and specific. For early infection diagnosis and subsequently for the prevention and treatment of periodontal disease, a rapid and accurate assessment of periodonto-pathogens is crucial. Bangladesh Journal of Medical Science Vol.22 (Special Issue) 2023 p.93-99
{"title":"Detection And Quantification Of Treponema Denticola In Subgingival Plaque Of Humans By Polymerase Chain Reaction","authors":"P. Kukreja, B. Kukreja, K. Bhat","doi":"10.3329/bjms.v22i20.66316","DOIUrl":"https://doi.org/10.3329/bjms.v22i20.66316","url":null,"abstract":"Introduction: Inflammation of the supporting tissues which is also known as periodontitis contributes to the major etiological factor for tooth loss. Consortium of pathogenic bacteria with elevated levels lead to onset and progression of periodontal disease. Gram negative bacteria, primarily severe anaerobes, are responsible for most of it.\u0000Aims and Objectives: The present study aimed to assess the presence of Treponema denticola in periodontal disease in different subgingival plaque samples collected from the oral cavity of 30 patients diagnosed with chronic periodontitis. The plaque samples were compared with similar plaque samples of 15 healthy patients.\u0000Method: Subgingival dental plaque samples from shallow and deep crevices were examined for the presence of bacterial DNA using the PCR method, which enables the simultaneous identification of multiple bacterial genomes.\u0000Results: PCR results show amplification and quantification of T. denticola in 10 out of 15 patients in group-1, 9 out of 15 patients in group-2, and 4 out of 15 patients in group-3. The statistical analyses of the results show that they are statistically significant.\u0000Conclusion: According to the aforementioned study, PCR microorganism identification is sensitive and specific. For early infection diagnosis and subsequently for the prevention and treatment of periodontal disease, a rapid and accurate assessment of periodonto-pathogens is crucial.\u0000Bangladesh Journal of Medical Science Vol.22 (Special Issue) 2023 p.93-99","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"11 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79480879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-21DOI: 10.3329/bjms.v22i20.66320
Iktefa Abdul Hamid Mohammed Saeed, Abdulrahman Aeed Salih, S. M. Abdulkareem
The current study was designed to investigate the effect of exercise on the level of the cortisol hormone and some physiological variables in male athletes. The cortisol, vitamin C, glutathione (GSH), and malondialdehyde (MDA) levels in the serum of twenty young male basketball players were measured before and after the exercise. The cortisol values and GSH levels showed a statistically significant decrease after physical effort compared to the result before training, in contrast to vitamin C and MDA levels represent a statistically significant increase. Decreasing cortisol levels after activity showed decreasing stress because exercise for years will reduce the stimulating effect of cortisol secretion. In addition, in response to increased oxidative stress caused by exercise, serum vitamin C increased to prevent oxidative stress. As a result, training in these athletes led to producing reactive oxygen species and thus increased lipid peroxidation, which increased MDA levels by exhausting the antioxidant defense system and reducing GSH levels. Measurement of these biomarkers allows the identification of players affected by severe oxidative stress and indicates the time of intervention for improving their performance and health. Bangladesh Journal of Medical Science Vol.22 (Special Issue) 2023 p.127-132
{"title":"Comparison of Cortisol and Some Physiological Biomarkers Among Athletes Following a Basketball Sports Performance","authors":"Iktefa Abdul Hamid Mohammed Saeed, Abdulrahman Aeed Salih, S. M. Abdulkareem","doi":"10.3329/bjms.v22i20.66320","DOIUrl":"https://doi.org/10.3329/bjms.v22i20.66320","url":null,"abstract":"The current study was designed to investigate the effect of exercise on the level of the cortisol hormone and some physiological variables in male athletes. The cortisol, vitamin C, glutathione (GSH), and malondialdehyde (MDA) levels in the serum of twenty young male basketball players were measured before and after the exercise. The cortisol values and GSH levels showed a statistically significant decrease after physical effort compared to the result before training, in contrast to vitamin C and MDA levels represent a statistically significant increase. Decreasing cortisol levels after activity showed decreasing stress because exercise for years will reduce the stimulating effect of cortisol secretion. In addition, in response to increased oxidative stress caused by exercise, serum vitamin C increased to prevent oxidative stress. As a result, training in these athletes led to producing reactive oxygen species and thus increased lipid peroxidation, which increased MDA levels by exhausting the antioxidant defense system and reducing GSH levels. Measurement of these biomarkers allows the identification of players affected by severe oxidative stress and indicates the time of intervention for improving their performance and health.\u0000Bangladesh Journal of Medical Science Vol.22 (Special Issue) 2023 p.127-132","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"23 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76535678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-21DOI: 10.3329/bjms.v22i20.66300
R. Saadi, E. Alobaidy, H. K. Ibrahim
Polycystic ovary syndrome (PCOS) is receiving increasing attention, due to its association with many health troubles such as infertility and diabetes. The purpose of our study is to estimate the serum level of some indicators in women patients with PCOS. This study was conducted prospectively on 70 participating women who attended Al-Batool Teaching Hospital in Baquba (Iraq), with ages between (18-35) years, from February 2020 to November 2022. All the participating women were separative into two groups: )Control( group included 30 healthy women,and (PCOS) group included 40 women suffer from polycystic ovary syndrome. Ultrasound and analyzes of the sex hormones of the participants were used to confirm the detection of PCOS. Serological biomarkers were measured for both groups, including histidine, ferritin, follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin, and estrogen (E2). Results proven a notable reduction in the serum levels of hepcidin and FSH in PCOS group compared to healthy control group. In contrast, a considerable increases in levels of LH, prolactin, ferritin, and estrogen E2 hormone were observed in patients with PCOS. It was founded that these biochemical indicators may be a reliable diagnostic measure for polycystic ovary syndrome cases. Bangladesh Journal of Medical Science Vol.22 (Special Issue) 2023 p.4-9
{"title":"Evaluation of Some Serological Indicators in Women with Polycystic Ovary Syndrome in Baquba , Iraq","authors":"R. Saadi, E. Alobaidy, H. K. Ibrahim","doi":"10.3329/bjms.v22i20.66300","DOIUrl":"https://doi.org/10.3329/bjms.v22i20.66300","url":null,"abstract":"Polycystic ovary syndrome (PCOS) is receiving increasing attention, due to its association with many health troubles such as infertility and diabetes. The purpose of our study is to estimate the serum level of some indicators in women patients with PCOS. This study was conducted prospectively on 70 participating women who attended Al-Batool Teaching Hospital in Baquba (Iraq), with ages between (18-35) years, from February 2020 to November 2022. All the participating women were separative into two groups: )Control( group included 30 healthy women,and (PCOS) group included 40 women suffer from polycystic ovary syndrome. Ultrasound and analyzes of the sex hormones of the participants were used to confirm the detection of PCOS. Serological biomarkers were measured for both groups, including histidine, ferritin, follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin, and estrogen (E2). Results proven a notable reduction in the serum levels of hepcidin and FSH in PCOS group compared to healthy control group. In contrast, a considerable increases in levels of LH, prolactin, ferritin, and estrogen E2 hormone were observed in patients with PCOS. It was founded that these biochemical indicators may be a reliable diagnostic measure for polycystic ovary syndrome cases.\u0000Bangladesh Journal of Medical Science Vol.22 (Special Issue) 2023 p.4-9","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"33 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82367801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-21DOI: 10.3329/bjms.v22i20.66302
Shahla Najim Abed Al Azzawi, R. Abdullah
Twenty –five isolates of Escherichia coli isolated from cases of diarrhea in children under five years of age were obtained, characterized by Extensively Drug-Resistant(XDR) resistance patterns, and sensitivity screening of isolates was performed.E7 isolates were resistant to 4 groups of antibiotics and E5 - E13 - E14 - E17 - E18 - E20 - E47 - E46 - E42 - E31 - E26 isolates resistant to 5 groups of antibiotics and 48E isolate resistance to 6 groups of antibiotics and consisting of E2 E38 - E36 - E34 - E28 - E16 - E10isolates showed resistance to 7 groups of antibiotics, and E41 - E24 - E19 - E9 –E1 isolates resistance to 8 groups of antibiotics. The genotyping of 25 E.coliisolates was carried out by Pulsed-field Gel Electrophoresis (PFGE) using restriction endonucleases (Xbal) which belong to different phylogenetic groups, were as group A, group B2, group D (2/25 and 8%) group C (4/25 and 16%), group F (3/25 and 12%), group E (12/25 and 48%). The genetic convergence rate of isolates is 83%, and this is due to the similarity in genetic content, the source of isolation, and the place of isolation itself. Bangladesh Journal of Medical Science Vol.22 (Special Issue) 2023 p.18-24
{"title":"Genotyping of Escherichia Coli Isolated from Diarrhea Cases in Children under Five Years of age Using the PFGE Method","authors":"Shahla Najim Abed Al Azzawi, R. Abdullah","doi":"10.3329/bjms.v22i20.66302","DOIUrl":"https://doi.org/10.3329/bjms.v22i20.66302","url":null,"abstract":"Twenty –five isolates of Escherichia coli isolated from cases of diarrhea in children under five years of age were obtained, characterized by Extensively Drug-Resistant(XDR) resistance patterns, and sensitivity screening of isolates was performed.E7 isolates were resistant to 4 groups of antibiotics and E5 - E13 - E14 - E17 - E18 - E20 - E47 - E46 - E42 - E31 - E26 isolates resistant to 5 groups of antibiotics and 48E isolate resistance to 6 groups of antibiotics and consisting of E2 E38 - E36 - E34 - E28 - E16 - E10isolates showed resistance to 7 groups of antibiotics, and E41 - E24 - E19 - E9 –E1 isolates resistance to 8 groups of antibiotics. The genotyping of 25 E.coliisolates was carried out by Pulsed-field Gel Electrophoresis (PFGE) using restriction endonucleases (Xbal) which belong to different phylogenetic groups, were as group A, group B2, group D (2/25 and 8%) group C (4/25 and 16%), group F (3/25 and 12%), group E (12/25 and 48%). The genetic convergence rate of isolates is 83%, and this is due to the similarity in genetic content, the source of isolation, and the place of isolation itself.\u0000Bangladesh Journal of Medical Science Vol.22 (Special Issue) 2023 p.18-24","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"14 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78241070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-21DOI: 10.3329/bjms.v22i20.66305
Arnab Bhattacharyya, H. Kumar, P. Mishra, Abikshyeet Panda, K. Dash, Tamanna Adhikary
Clustered Regularly InterSpaced Palindromic Repeats is known as CRISPR. It is a protein that can be programmed to change, eliminate, or activate the genome. This cutting-edge technology offers a broad range of possible implementation and is poised to revolutionise oral healthcare in the years to come. The most widely utilised genome editing techniques include homing endonucleases, Transcription Activator-Like Effector Nucleases, Zinc-Finger Nucleases, and CRISPR- CRISPR-associated protein 9 (Cas9). These adaptable genome-editing tools can alter the genomes in ways that are sequence-specific. Because it is highly effective and accurate, the genome editing method CRISPR-Cas9 has drawn attention as a potent weapon in the fight against cancer. This method and its uses, particularly in dental field, are covered in this review. Bangladesh Journal of Medical Science Vol.22 (Special Issue) 2023 p.42-46
{"title":"CRISPR Technology- A New Horizon in Clinical Dentistry- A Review","authors":"Arnab Bhattacharyya, H. Kumar, P. Mishra, Abikshyeet Panda, K. Dash, Tamanna Adhikary","doi":"10.3329/bjms.v22i20.66305","DOIUrl":"https://doi.org/10.3329/bjms.v22i20.66305","url":null,"abstract":"Clustered Regularly InterSpaced Palindromic Repeats is known as CRISPR. It is a protein that can be programmed to change, eliminate, or activate the genome. This cutting-edge technology offers a broad range of possible implementation and is poised to revolutionise oral healthcare in the years to come. The most widely utilised genome editing techniques include homing endonucleases, Transcription Activator-Like Effector Nucleases, Zinc-Finger Nucleases, and CRISPR- CRISPR-associated protein 9 (Cas9). These adaptable genome-editing tools can alter the genomes in ways that are sequence-specific. Because it is highly effective and accurate, the genome editing method CRISPR-Cas9 has drawn attention as a potent weapon in the fight against cancer. This method and its uses, particularly in dental field, are covered in this review.\u0000Bangladesh Journal of Medical Science Vol.22 (Special Issue) 2023 p.42-46","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"37 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75999665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-21DOI: 10.3329/bjms.v22i20.66323
Sarita Rawal Rimal Upadhaya, Sarla Pradhan Joshi, Ahmad Fairuz Bin Mohamed, K. Rampal
Aim: The specific aim of the study was to assess the impact of COVID-19 pandemic on nursing faculty experiences. Background: Academic nursing experiences were disrupted due to the COVID-19 pandemic. There is concern that the resulting stress threatens nursing faculty emotional well-being and reason to burnout. Method: A descriptive, quantitative study was conducted; exploring faculty academic and clinical roles during the COVID-19 pandemic by using structured, self designed, open-ended questionnaire to 401 institutionally attached nursing health professionals. The questionnaire includes various domains including Safety and Health, Challenges for teaching, clinical practise, supervision perception of institutional support provided; faculty burnout, satisfaction, and well-being. Results: Overall satisfaction with the working environment in the institutions with respect to total teaching experience showed a significant statistical. Participants perceived support from academic institutions and increased need to provide emotional support to students. Conclusion: Nursing faculty are essential to the profession. Nursing faculty require proactive and sustained institutional and personal support to provide exceptional ongoing education, build resilience, and support students. Bangladesh Journal of Medical Science Vol.22 (Special Issue) 2023 p.148-156
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