Pub Date : 2024-01-02DOI: 10.3329/bjms.v23i1.70674
K. Alawneh, S. Jaradat, Marya Obeidat, Tariq Kewan, D. Zahran, D. Alawneh, N. Sweiss
Objectives: Familial Mediterranean Fever (FMF) is an autosomal-recessive disorder caused by mutations in MEFV gene. Hundreds of mutations have been described in patients with FMF. The aim of this study was to analyze the common genotypes of Arab patients with FMF from Jordan and to establish genotypephenotype correlation patterns. Methods: This cross-sectional retrospective study was performed in a tertiary hospital in the north of Jordan. A total of 123 patients with FMF were recruited from the rheumatology outpatient clinic at King Abdullah University Hospital. Patients were diagnosed according to Tel-Hashomer criteria and a carrier of at least one previously identified MEFV gene mutation. Demographics and clinical manifestations were recorded. Results: Mean age at diagnosis was 17.49 years and M:F ratio was 1.05:1. The following mutations were common among our patients: R202Q (41.4%), M694V (22.1%), E148Q (10.3%), V726A (11.3%), M680I (5.3%), and M694I (3.7%). Among them 26% were homozygous, 11% were compound homozygous, 26% heterozygous, 42% were compound heterozygous, and 18% were other complex genotype including homozygosity and heterozygosity of more than one mutation. As for genotype-phenotype correlation, 65% of the patients with skin rash had R202Q mutation, while M694V mutation was associated with abdominal and chest pain. Amyloidosis correlated most with the M694I mutation (66.7%). Conclusion: The results confirm the frequency of the previously and commonly identified mutations and highlight the association of R202Q polymorphism with skin rash phenotype among adult Jordanian FMF patients. Additionally, both M694V and M694I mutations were associated with different clinical presentations. Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 54-62
{"title":"Genotypes and Phenotypes of Arab Patients with Familial Mediterranean Fever in North Jordan","authors":"K. Alawneh, S. Jaradat, Marya Obeidat, Tariq Kewan, D. Zahran, D. Alawneh, N. Sweiss","doi":"10.3329/bjms.v23i1.70674","DOIUrl":"https://doi.org/10.3329/bjms.v23i1.70674","url":null,"abstract":"Objectives: Familial Mediterranean Fever (FMF) is an autosomal-recessive disorder caused by mutations in MEFV gene. Hundreds of mutations have been described in patients with FMF. The aim of this study was to analyze the common genotypes of Arab patients with FMF from Jordan and to establish genotypephenotype correlation patterns. \u0000Methods: This cross-sectional retrospective study was performed in a tertiary hospital in the north of Jordan. A total of 123 patients with FMF were recruited from the rheumatology outpatient clinic at King Abdullah University Hospital. Patients were diagnosed according to Tel-Hashomer criteria and a carrier of at least one previously identified MEFV gene mutation. Demographics and clinical manifestations were recorded. \u0000Results: Mean age at diagnosis was 17.49 years and M:F ratio was 1.05:1. The following mutations were common among our patients: R202Q (41.4%), M694V (22.1%), E148Q (10.3%), V726A (11.3%), M680I (5.3%), and M694I (3.7%). Among them 26% were homozygous, 11% were compound homozygous, 26% heterozygous, 42% were compound heterozygous, and 18% were other complex genotype including homozygosity and heterozygosity of more than one mutation. As for genotype-phenotype correlation, 65% of the patients with skin rash had R202Q mutation, while M694V mutation was associated with abdominal and chest pain. Amyloidosis correlated most with the M694I mutation (66.7%). \u0000Conclusion: The results confirm the frequency of the previously and commonly identified mutations and highlight the association of R202Q polymorphism with skin rash phenotype among adult Jordanian FMF patients. Additionally, both M694V and M694I mutations were associated with different clinical presentations. \u0000Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 54-62","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"105 44","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139391092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Excessive weight gain in individuals leads to various metabolic disorders, such as diabetes mellitus, contributing to a further increase in body mass index (BMI). Thus, the patient enters a vicious cycle that leads to irreversible health damage. Bariatric surgery has displayed positive outcomes of weight loss with the return of BMI towards normal, which may reduce blood glucose levels to near normal. The remission of diabetes mellitus may be attributed to the reduction in inflammation, improvement of insulin resistance, lowering of peptide YY, and overall improved metabolic state of the body. Methods: One fifty patients, both female and male, in the age group of 20-60 years with grade II and grade III obesity having mean BMI of 45.63±6.54 (male) and 41.81± 5.93kg/m2 (female) were randomly selected for this study. Hemoglobin, Fasting Blood sugar (FBS), 2 hours postprandial blood sugar (PP2BS). Hemoglobin A1c (HbA1c) serum insulin was assessed at the visit, marked as a baseline, then again at the visit 3 months, and finally at the visit by the patient 6 months after bariatric surgery. Results: Hemoglobin level increased significantly from baseline at the 3rd-month post-surgery visit. FBS increased substantially from baseline at the 3rd-month postsurgery visit, which decreased considerably at the 6th-month visit following surgery. HbA1c showed a significant decrease in level from baseline following surgery. Conclusion: Improvement in BMI following bariatric surgery may have a positive impact on blood glucose levels in diabetic patients who may hope to see better management of their condition and may enjoy a better quality of life. Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 29-38
{"title":"One Anastomosis Gastric Bypass Surgery: Consequences Over Diabetic Parameters","authors":"Arya Singh, Rahnuma Ahmad, Susmita Sinha, Md. Ahsanul Haq, M. Narwaria, Ankur Sharma, Mainul Haque, Santosh Kumar, Nandita Sanghani","doi":"10.3329/bjms.v23i1.70666","DOIUrl":"https://doi.org/10.3329/bjms.v23i1.70666","url":null,"abstract":"Introduction: Excessive weight gain in individuals leads to various metabolic disorders, such as diabetes mellitus, contributing to a further increase in body mass index (BMI). Thus, the patient enters a vicious cycle that leads to irreversible health damage. Bariatric surgery has displayed positive outcomes of weight loss with the return of BMI towards normal, which may reduce blood glucose levels to near normal. The remission of diabetes mellitus may be attributed to the reduction in inflammation, improvement of insulin resistance, lowering of peptide YY, and overall improved metabolic state of the body. \u0000Methods: One fifty patients, both female and male, in the age group of 20-60 years with grade II and grade III obesity having mean BMI of 45.63±6.54 (male) and 41.81± 5.93kg/m2 (female) were randomly selected for this study. Hemoglobin, Fasting Blood sugar (FBS), 2 hours postprandial blood sugar (PP2BS). Hemoglobin A1c (HbA1c) serum insulin was assessed at the visit, marked as a baseline, then again at the visit 3 months, and finally at the visit by the patient 6 months after bariatric surgery. \u0000Results: Hemoglobin level increased significantly from baseline at the 3rd-month post-surgery visit. FBS increased substantially from baseline at the 3rd-month postsurgery visit, which decreased considerably at the 6th-month visit following surgery. HbA1c showed a significant decrease in level from baseline following surgery. \u0000Conclusion: Improvement in BMI following bariatric surgery may have a positive impact on blood glucose levels in diabetic patients who may hope to see better management of their condition and may enjoy a better quality of life. \u0000Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 29-38","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"129 33","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139453317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: The most familiar kidney disease in children is nephrotic syndrome (NS), associated with dyslipidemia and causes various cardiovascular complications. Persistent hyperlipidemia can further raise difficulties of NS and relapse cases. Earlier diagnosis and appropriate intervention increase the possibility of saving other vital organs. Methods: An observational study was conducted with 85 children aged 2-15 years with a history of NS. The study group was divided into first NS and second-episode relapse cases. They were further subgrouped into Frequent Relapse NS (FRNS) and Infrequent Relapse NS (IFRNS). Fasting lipid profiles were performed among active sufferers with a follow-up after 4 weeks. Results: The male-to-female ratio was 1.93:1. In the first episode of NS, all lipid parameters were high in the acute phase and returned to normal during remission. In relapse cases, lipid parameters were significantly higher even in remission. Serum triglyceride and very low-density lipoprotein were significantly more elevated in the FRNS group than in the IFRNS. Low-density lipoprotein was increased considerably in FRNS. Mean high-density lipoprotein was also significantly lower in the FRNS group than in the IFRNS. Conclusion: Persistent hyperlipidemia is most typical among FRNS. Hyperlipidemia management is urgent to prevent among pediatric NS. Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 39-46
{"title":"Serum lipid profile among pediatric folk with idiopathic nephrotic syndrome: An Observational Study","authors":"Partha Kumar Chaudhuri, Akanksha Kumari, Ananya Ghosh, Basant Kumar, Pankaj Kumar, Shreya Gajjar, Md. Ahsanul Haq, Susmita Sinha, Mainul Haque, Santosh Kumar","doi":"10.3329/bjms.v23i1.70671","DOIUrl":"https://doi.org/10.3329/bjms.v23i1.70671","url":null,"abstract":"Introduction: The most familiar kidney disease in children is nephrotic syndrome (NS), associated with dyslipidemia and causes various cardiovascular complications. Persistent hyperlipidemia can further raise difficulties of NS and relapse cases. Earlier diagnosis and appropriate intervention increase the possibility of saving other vital organs. \u0000Methods: An observational study was conducted with 85 children aged 2-15 years with a history of NS. The study group was divided into first NS and second-episode relapse cases. They were further subgrouped into Frequent Relapse NS (FRNS) and Infrequent Relapse NS (IFRNS). Fasting lipid profiles were performed among active sufferers with a follow-up after 4 weeks. \u0000Results: The male-to-female ratio was 1.93:1. In the first episode of NS, all lipid parameters were high in the acute phase and returned to normal during remission. In relapse cases, lipid parameters were significantly higher even in remission. Serum triglyceride and very low-density lipoprotein were significantly more elevated in the FRNS group than in the IFRNS. Low-density lipoprotein was increased considerably in FRNS. Mean high-density lipoprotein was also significantly lower in the FRNS group than in the IFRNS. \u0000Conclusion: Persistent hyperlipidemia is most typical among FRNS. Hyperlipidemia management is urgent to prevent among pediatric NS. \u0000Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 39-46","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"98 5","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139390386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Essential Steps in Writing and Publishing a Scientific Research Paper","authors":"R. Yousuf, Mushtahid Salam, Shaeri Jahra Amreen, Hasbullani Zakaria, J. Zainol, Abdus Salam, Abu Kholdun Al Mahmood","doi":"10.3329/bjms.v23i1.70663","DOIUrl":"https://doi.org/10.3329/bjms.v23i1.70663","url":null,"abstract":"Abstract not available \u0000Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 12-17","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"105 49","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139391265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Human-on-Chip Technology: Current State and Future Challenges","authors":"Santosh Kumar, Namrata Dagli, Mainul Haque","doi":"10.3329/bjms.v23i1.70657","DOIUrl":"https://doi.org/10.3329/bjms.v23i1.70657","url":null,"abstract":"Abstract not available \u0000Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 7-11","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"135 39","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139453042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: The symptoms of allergic responses, such as hay fever or urticaria, can be relieved with the use of ebastine, an efficient anti-allergic medication. Objective & Method: This study’s primary objective was to assess and contrast various quality control parameters, such as weight variation, % friability, hardness, disintegration time, dissolution profile, and potency, of the twelve different brands of Ebastine tablets that were readily available in Bangladesh in accordance with compendia procedures. It’s interesting to note that, according to various official requirements, all of the quality parameters indicated above were within acceptable bounds. Conclusion: Therefore, doctors can advise patients to use any of the Ebastine brands that are sold in Bangladesh. Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 47-53
{"title":"Comparative in-vitro evaluation of ebastine tablets (10 mg) available in bangladesh","authors":"S. Mimmi, Saqib Rahman, Prethula Areefin, Md. Shaki Mostaid, Md Ayman Siddique, Md Aminul Haque","doi":"10.3329/bjms.v23i1.70673","DOIUrl":"https://doi.org/10.3329/bjms.v23i1.70673","url":null,"abstract":"Background: The symptoms of allergic responses, such as hay fever or urticaria, can be relieved with the use of ebastine, an efficient anti-allergic medication. \u0000Objective & Method: This study’s primary objective was to assess and contrast various quality control parameters, such as weight variation, % friability, hardness, disintegration time, dissolution profile, and potency, of the twelve different brands of Ebastine tablets that were readily available in Bangladesh in accordance with compendia procedures. It’s interesting to note that, according to various official requirements, all of the quality parameters indicated above were within acceptable bounds. \u0000Conclusion: Therefore, doctors can advise patients to use any of the Ebastine brands that are sold in Bangladesh. \u0000Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 47-53","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"45 7","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139390574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-02DOI: 10.3329/bjms.v23i1.70664
Ninie Nadia Zulkipli, Idris Long, H. Wahab, T. H. Sasongko, A. H. Ahmad, Zahiruddin Othman, Aidi Ahmi, R. Zakaria
Background: Tuberous sclerosis complex (TSC) is a rare autosomal dominant multisystem disease resulting from hyperactivation of the mammalian target of rapamycin (mTOR) signaling pathway. This study aimed to measure the quantitative impact of publications in TSC. Materials and methods: We analysed TSC literature obtained from the Scopus database using Bibliometrix R Package and VOSviewer software. Annual publication trends, most productive and collaborative authors/institutions/ countries, most cited articles, most popular journals and author’s keywords were presented using standard bibliometric indicators. Results and discussion: A total of 5375 documents on TSC were published from 1960 to December 2020, with an increasing trend. The three primary contributing writers were Curatolo P, Kwiatkowski DJ, and Thiele EA, with the United States and its institutions being the largest contributor. The research identified two of the most referenced papers as TSC’s seminal pieces. The top journals that published TSC research were medical journals, namely Journal of Child Neurology, Epilepsia, and Pediatric Neurology. mTOR inhibitor, everolimus, sirolimus, mTORC1, mTOR pathway, autophagy, inflammation, infant, intellectual disability, white matter, TSC-associated neuropsychiatric disorders, TOSCA and quality of life were relatively newer author’s keywords and may indicate the future research hotspots in TSC research. Conclusion: Over the last few decades, TSC research has grown in importance, particularly in the field of clinical medicine. Therapeutic components targeting TSC-related pathways, the utilisation of TSC as disease models and long-term safety studies will be future research areas. Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 18-28
{"title":"Bibliometric analysis and network visualization on Tuberous Sclerosis Complex","authors":"Ninie Nadia Zulkipli, Idris Long, H. Wahab, T. H. Sasongko, A. H. Ahmad, Zahiruddin Othman, Aidi Ahmi, R. Zakaria","doi":"10.3329/bjms.v23i1.70664","DOIUrl":"https://doi.org/10.3329/bjms.v23i1.70664","url":null,"abstract":"Background: Tuberous sclerosis complex (TSC) is a rare autosomal dominant multisystem disease resulting from hyperactivation of the mammalian target of rapamycin (mTOR) signaling pathway. This study aimed to measure the quantitative impact of publications in TSC. \u0000Materials and methods: We analysed TSC literature obtained from the Scopus database using Bibliometrix R Package and VOSviewer software. Annual publication trends, most productive and collaborative authors/institutions/ countries, most cited articles, most popular journals and author’s keywords were presented using standard bibliometric indicators. \u0000Results and discussion: A total of 5375 documents on TSC were published from 1960 to December 2020, with an increasing trend. The three primary contributing writers were Curatolo P, Kwiatkowski DJ, and Thiele EA, with the United States and its institutions being the largest contributor. The research identified two of the most referenced papers as TSC’s seminal pieces. The top journals that published TSC research were medical journals, namely Journal of Child Neurology, Epilepsia, and Pediatric Neurology. mTOR inhibitor, everolimus, sirolimus, mTORC1, mTOR pathway, autophagy, inflammation, infant, intellectual disability, white matter, TSC-associated neuropsychiatric disorders, TOSCA and quality of life were relatively newer author’s keywords and may indicate the future research hotspots in TSC research. \u0000Conclusion: Over the last few decades, TSC research has grown in importance, particularly in the field of clinical medicine. Therapeutic components targeting TSC-related pathways, the utilisation of TSC as disease models and long-term safety studies will be future research areas. \u0000Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 18-28","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"71 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139452656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In response to ‘Mastectomy under Local Anesthesia in Locally Advanced Breast Cancer in an Unfit Patient","authors":"BM Munasinghe","doi":"10.3329/bjms.v23i1.70774","DOIUrl":"https://doi.org/10.3329/bjms.v23i1.70774","url":null,"abstract":"Abstract not available \u0000Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 276-277","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":" 28","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139392077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.3329/bjms.v23i1.70762
Mohammad Zawawi Ya’acob, I. S. Mohamad, Leow Voon Meng, Maya Mazuwin Yahya, Nagarajan T Vellasamy
Gallstone disease is a common burden that affect worldwide that carry broad spectrum of its complications and severities. Gallstone ileus (GSI) remained the rare complication that arise form gallstone disease that mainly affected the elderly population. The mainstay of treatment for GSI is to relieve the small bowel obstruction by extraction of the impacted gallstone. Surgical options for GSI remained the long-standing arguments involve single-staged procedure (enterolithotomy, cholecystectomy and fistula repair) or twostaged procedure (enterolithotomy alone, and cholecystectomy with fistula repair later). We reported a case of a 76-year-old male who presented with symptoms of small bowel obstruction and computed tomography (CT) of abdomen confirmed the presence of calcified lesion at ileum with pneumobilia which was successfully managed with two-staged procedure. Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 272-275
{"title":"Gallstone Ileus: Unfortunate Encounter","authors":"Mohammad Zawawi Ya’acob, I. S. Mohamad, Leow Voon Meng, Maya Mazuwin Yahya, Nagarajan T Vellasamy","doi":"10.3329/bjms.v23i1.70762","DOIUrl":"https://doi.org/10.3329/bjms.v23i1.70762","url":null,"abstract":"Gallstone disease is a common burden that affect worldwide that carry broad spectrum of its complications and severities. Gallstone ileus (GSI) remained the rare complication that arise form gallstone disease that mainly affected the elderly population. The mainstay of treatment for GSI is to relieve the small bowel obstruction by extraction of the impacted gallstone. Surgical options for GSI remained the long-standing arguments involve single-staged procedure (enterolithotomy, cholecystectomy and fistula repair) or twostaged procedure (enterolithotomy alone, and cholecystectomy with fistula repair later). We reported a case of a 76-year-old male who presented with symptoms of small bowel obstruction and computed tomography (CT) of abdomen confirmed the presence of calcified lesion at ileum with pneumobilia which was successfully managed with two-staged procedure. \u0000Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 272-275","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"106 s415","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139393785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.3329/bjms.v23i1.70714
Rehana Basri, Mubarak Alruwaili, Raed Alruwaili, B. Altaleb, Abdulrahman B. Almazyad, F. Alrayes, S. Albulayhid, Amer Abdulaziz Alharbi, Abdullah Qasem Alruwaili, B. Albilasi, Rehab Ali Alanazi, Hamasat Alsharari, A. N. Alruwaili
Background: Stroke is a common neurological disorder with a high prevalence. The aim of this study was to determine the risk factor, prevalence, and association of types of strokes among diabetes and hypertension patients. Methods: A retrospective study was conducted in King Abdul Aziz, Qurayyat, Sakaka, and Tubarjal hospitals among stroke patients including both sexes within the age > 40 years. Type of stroke was identified by brain computed tomography scans or magnetic resonance imaging and risk factors for stroke and other details were noted on a checklist. Results: Out of 226 stroke patients considered for the present study, in which 48% were males and 52% were females. All lived in the Aljouf region. Most of the patients had risk factors which included Hypertension 49 (21.68%), Diabetes Mellitus 44 (19.46%), Combined (Hypertension and diabetes) 111 (49.11%), and Hyperlipidemia 22 (9.75%). Stroke patients > 60 years of age group showed a higher prevalence of ischemic stroke (p=0.001). The combined risk factor group also showed more prevalence of ischemic stroke (49.11%). Conclusion: Patient having both risk factor Hypertension and diabetes mellitus were major association with ischemic stroke. Majority of the patients with ischemic stroke age at onset > 60 year and irrespectively affected both males and females were equally. Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 171-178
{"title":"Determining the effect of hypertension and diabetes following stroke in tertiary hospital, Aljouf, Saudi Arabia.","authors":"Rehana Basri, Mubarak Alruwaili, Raed Alruwaili, B. Altaleb, Abdulrahman B. Almazyad, F. Alrayes, S. Albulayhid, Amer Abdulaziz Alharbi, Abdullah Qasem Alruwaili, B. Albilasi, Rehab Ali Alanazi, Hamasat Alsharari, A. N. Alruwaili","doi":"10.3329/bjms.v23i1.70714","DOIUrl":"https://doi.org/10.3329/bjms.v23i1.70714","url":null,"abstract":"Background: Stroke is a common neurological disorder with a high prevalence. The aim of this study was to determine the risk factor, prevalence, and association of types of strokes among diabetes and hypertension patients. \u0000Methods: A retrospective study was conducted in King Abdul Aziz, Qurayyat, Sakaka, and Tubarjal hospitals among stroke patients including both sexes within the age > 40 years. Type of stroke was identified by brain computed tomography scans or magnetic resonance imaging and risk factors for stroke and other details were noted on a checklist. \u0000Results: Out of 226 stroke patients considered for the present study, in which 48% were males and 52% were females. All lived in the Aljouf region. Most of the patients had risk factors which included Hypertension 49 (21.68%), Diabetes Mellitus 44 (19.46%), Combined (Hypertension and diabetes) 111 (49.11%), and Hyperlipidemia 22 (9.75%). Stroke patients > 60 years of age group showed a higher prevalence of ischemic stroke (p=0.001). The combined risk factor group also showed more prevalence of ischemic stroke (49.11%). \u0000Conclusion: Patient having both risk factor Hypertension and diabetes mellitus were major association with ischemic stroke. Majority of the patients with ischemic stroke age at onset > 60 year and irrespectively affected both males and females were equally. \u0000Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 171-178","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"121 16","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139453876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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