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Obstruktive Lungenkrankheiten: Asthma und COPD 气喘活症:哮喘和COPD
Jörg D. Leuppi
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引用次数: 0
[Interventionen beim Asthma COPD]. 哮喘治疗
Neha P. Mandovra, Jörg D. Leuppi, F. Herth, P. Chhajed
Advanced emphysema and asthma constitute major health burden worldwide and are associated with significant morbidity and mortality. Pharmacological options are limited. Researches are being carried out aiming to modify the natural course of both the diseases. Lung volume reduction surgeries are performed in advanced emphysema but are associated with significant morbidity and prolonged hospital stay. Various minimally invasive bronchoscopic methods have been developed with the goal of achieving clinical benefits of volume reduction surgery but lower complications. Bronchial thermoplasty is a bronchoscopic method of delivering controlled heat in the airways to reduce airway smooth muscle mass, thereby reducing bronchoconstriction in patients with severe asthma who remain uncontrolled despite optimal medical therapy. Various randomised controlled trials have been performed to evaluate the safety and efficacy of various endoscopic treatments like valves, coils, use of sclerosants and targeted lung denervation for severe emphysema and bronchial thermoplasty in severe asthma. The current review summaries the clinical trial evidence available for lung volume reduction in emphysema and thermoplasty in asthma and provide guidance for optimal patient selection for various therapies available.
晚期肺气肿和哮喘在世界范围内构成了主要的健康负担,并与显著的发病率和死亡率相关。药物选择是有限的。目前正在进行旨在改变这两种疾病的自然病程的研究。肺减容手术可用于晚期肺气肿,但与显著的发病率和延长住院时间有关。各种微创支气管镜方法的发展目标是实现体积缩小手术的临床效益,同时降低并发症。支气管热成形术是一种支气管镜下的方法,在气道中传递受控的热量,以减少气道平滑肌质量,从而减少严重哮喘患者的支气管收缩,尽管有最佳的药物治疗,但仍不受控制。已经进行了各种随机对照试验,以评估各种内窥镜治疗的安全性和有效性,如瓣膜、线圈、硬化剂的使用和针对严重肺气肿和严重哮喘的支气管热成形术的靶向肺去神经。目前的综述总结了肺气肿肺体积缩小和哮喘热成形术的临床试验证据,并为各种可用治疗方法的最佳患者选择提供指导。
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引用次数: 1
[Pulmonary Rehabilitation]. (肺康复)。
M. Frey
Pulmonary Rehabilitation Abstract. Pulmonary rehabilitation is a comprehensive therapeutic approach for patients with advanced chronic lung diseases which leads to a decline of dyspnea, an increase of exercise capacity and an increase of quality of life. Further effects are a reduction of frequency of hospitalisations and an increase of physical activity, if a self management education program is integrated. Pulmonary rehabilitation incorporates an individualised training program with focus on endurance, strength and mobility, further a disease specific education with the goal to improve self efficacy and self management of the patients, specially with the goal to improve their daily physical activity. Due to the good evidence of pulmonary rehabilitation, the accredited programs are accepted and paid by the swiss insurances.
肺康复摘要。肺部康复是晚期慢性肺部疾病患者呼吸困难减轻、运动能力增强、生活质量提高的综合治疗手段。如果将自我管理教育方案结合起来,进一步的影响是住院频率的降低和身体活动的增加。肺部康复包括一个个性化的训练计划,重点是耐力,力量和活动能力,进一步的疾病具体教育,目的是提高自我效能和自我管理的病人,特别是目标是改善他们的日常身体活动。由于肺部康复的良好证据,认可的计划被瑞士保险公司接受和支付。
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引用次数: 0
Kortikosteroide in der Behandlung des Asthmas und der COPD 哮喘治疗中的皮质类固醇
T. Rothe
The data situation for the use of ICS in asthma is clear. In the case of COPD, on the other hand, where in recent years the pendulum has moved away from ICS towards a dual therapy based on LABA / LAMA, the discussion is open again thanks to new work. However, it would certainly be wrong to recommend ICS as a meaningful therapy for all COPD patients at this point in time, since therapy with ICS is associated with side effects, in particular an increase in the risk of developing pneumonia or osteoporosis. However, there is no doubt that patients with asthma COPD overlap require ICS therapy.
ICS治疗哮喘的数据情况是明确的。另一方面,在慢性阻塞性肺病的情况下,近年来,人们已经从ICS转向基于LABA / LAMA的双重治疗,由于新的研究,讨论再次开放。然而,在这个时间点上,推荐ICS作为所有COPD患者的有意义的治疗方法肯定是错误的,因为ICS治疗与副作用有关,特别是增加患肺炎或骨质疏松症的风险。然而,毫无疑问,哮喘COPD重叠患者需要ICS治疗。
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引用次数: 0
[Treatment of Psychosomatic Disorders - Psychotherapy with Eye-Movement Desensitization and Reprocessing]. 心身疾病的治疗——眼动脱敏与再加工的心理治疗
Oliver Schubbe
Treatment of Psychosomatic Disorders - Psychotherapy with Eye-Movement Desensitization and Reprocessing Abstract. Dysfunctional stored memory information is a possible cause of psychosomatic disorders. EMDR (Eye-Movement Desensitization and Reprocessing) is based on the Adaptive Information Processing Model. This psychotherapeutic approach can be used to treat psychosomatic disorders to activate the pathogenic information and convert it from a dysfunctional to an adaptive state. EMDR has been scientifically proven for the treatment of posttraumatic stress disorders, while the treatment of psychosomatic disorders is a new field of application. Recently, studies have documented the effectiveness of EMDR with migraine headaches, skin diseases, gastrointestinal diseases, chronic fatigue syndrome, chronic pain syndrome, and phantom limb pain.
心身疾病的治疗——眼动脱敏与再加工的心理治疗功能失调的记忆信息存储是心身疾病的一个可能原因。眼动脱敏与再处理(EMDR)是一种基于自适应信息处理模型的方法。这种心理治疗方法可以用于治疗心身疾病,激活致病信息,将其从功能失调状态转化为适应状态。EMDR治疗创伤后应激障碍已被科学证实,而治疗心身障碍是一个新的应用领域。最近,研究证明了EMDR治疗偏头痛、皮肤病、胃肠道疾病、慢性疲劳综合征、慢性疼痛综合征和幻肢痛的有效性。
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引用次数: 0
Onkologie – Moderne Diagnostik und Therapie 现代诊断学与治疗
S. Rothschild, A. Zippelius
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引用次数: 0
Update zu Ernährung, Adipositas, bariatrische und metabole Chirurgie 有关饮食肥胖肥胖高血压的外科手术
R. Peterli, M. von Flüe
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引用次数: 0
Dermatologie für den Allgemeinpraktiker – Dermatology for General Physicians 一般物理学物理学
P. Itin
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引用次数: 0
Die verschiedenen Gesichter der Ekzeme 湿疹患者的不同脸
A. Cozzio, I. Saulīte
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引用次数: 0
[Modern concept of pruritus diagnosis and therapy]. 【瘙痒症诊断与治疗的现代观念】。
M. Streit
Modern concept of pruritus diagnosis and therapy Abstract. Pruritus can be best treated when the cause of itching is known, allowing a targeted treatment. To find the cause of itching it is recommended to consult the itch classification system of the «International Forum for the Study of Itch» (IFSI). In here three groups of conditions are distinguished: Pruritus on diseased (inflamed) skin (group I) is caused by a pruritic skin disorder that has to be diagnosed properly; correct treatment of the skin disorder will be the treatment of pruritus. Pruritus on non-diseased (non-inflamed) skin (group II) can be due to an internal disease or a consequence of drugs; elimination of the cause - as far as possible - will also eliminate itch. In pruritus presenting with severe chronic secondary scratch lesions (group III) the aim will be to prevent patients from further scratching. If causative treatment is not possible or the cause of itch remains unknown a symptomatic treatment will be seeked following a step-by-step procedure. In a step 1 a basic therapy with moisturizers and anthistamines is recommended. Step 2 comprises a symptomatic causative adapted therapy. In step 3 phototherapy and systemic treatments are considered including the use of anticonvulsants, antidepressants or anti-inflammatory agents.
瘙痒症诊断与治疗的现代观念当瘙痒的原因已知时,瘙痒可以得到最好的治疗,允许有针对性的治疗。为了找到瘙痒的原因,建议查阅“国际瘙痒研究论坛”(IFSI)的瘙痒分类系统。这里区分了三组情况:患病(发炎)皮肤上的瘙痒(第一组)是由瘙痒性皮肤病引起的,必须正确诊断;正确治疗皮肤病就会治疗瘙痒症。非病变(非发炎)皮肤瘙痒(II组)可能是由于内部疾病或药物的后果;消除原因-尽可能-也将消除瘙痒。在出现严重的慢性继发性抓挠损伤的瘙痒(III组),目的是防止患者进一步抓挠。如果病因治疗是不可能的,或瘙痒的原因仍然未知,一个对症治疗将寻求以下一步一步的程序。在第一步中,建议使用保湿霜和抗胺类药物进行基本治疗。步骤2包括对症致病适应疗法。在第三步中,考虑光疗和全身治疗,包括使用抗惊厥药、抗抑郁药或抗炎药。
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引用次数: 0
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Therapeutische Umschau und medizinische Bibliographie. Revue therapeutique et bibliographie medicale
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