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Latent Growth Curve Modeling of Ordinal Scales: A Comparison of Three Strategies 有序尺度的潜在增长曲线建模:三种策略的比较
Pub Date : 2017-01-01 DOI: 10.4172/2155-6180.1000383
Chongming Yang, J. Olsen, S. Coyne, Jing Yu
Ordinal scales can be used in latent growth curve modeling in three ways: mean, weighted mean scores, and factors measured by scale items. Sum and mean scores are commonly used in growth curve modeling in spite of certain discouragement. It was unclear how much bias these practices could produce in terms of the change rates and patterns. This study compared three methods with Monte Carlo Simulations under different number of response categories of the items, in terms of five key parameters of growth curve modeling. The hypothetical population models were derived from real empirical data to generate datasets of binary, trichotomous, five- and seven-point scales with sample size of 300. Latent growth curve modeling of mean, weighted mean, and factors measured by the ordinal scales were respectively fit to these datasets. Results indicated that modeling the factors that are measured with ordinal scales yield the fewest biases. Biases of modeling the means and weighted of the scales were under one decimal point in the change rates, whereas biases in the variances and covariance of the intercept and slope factors were large. In conclusion, it is inadvisable to use means or weighted means of ordinal scales for latent growth curve modeling. It produces the best results modeling the factors that are measured with the ordinal scales.
在潜在增长曲线建模中,顺序量表可以通过三种方式使用:平均、加权平均得分和量表项目测量的因素。和和平均分数是生长曲线建模中常用的方法,尽管有一些缺点。目前尚不清楚这些做法在变化速度和模式方面可能产生多大的偏差。本研究从生长曲线建模的5个关键参数出发,比较了蒙特卡罗模拟在不同项目响应类别数下的3种方法。根据实际经验数据推导出假设的人口模型,生成样本容量为300的二分制、三分制、五分制和七分制数据集。分别对这些数据集进行均值、加权均值和顺序尺度测量因子的潜在生长曲线模型拟合。结果表明,用有序尺度测量的因素建模产生的偏差最小。在变化率中,对尺度均值和加权的建模偏差小于一个小数点,而截距因子和斜率因子的方差和协方差偏差较大。综上所述,不宜采用顺序尺度的均值或加权均值进行潜在生长曲线建模。它产生了最好的结果建模的因素,测量与序数尺度。
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引用次数: 1
Methods for the Analysis of Missing Data in FMRI Studies. 功能磁共振成像研究中缺失数据的分析方法。
Pub Date : 2017-01-01 Epub Date: 2017-02-08 DOI: 10.4172/2155-6180.1000335
Gebregziabher Mulugeta, Mark A Eckert, Kenneth I Vaden, Timothy D Johnson, Andrew B Lawson
Functional neuroimaging has provided fundamental advances in our understanding of human brain function and is increasingly used clinically for defining atypical function and surgical planning. For example, functional imaging with blood oxygenation level dependent (BOLD) contrast as a response measure is used as a clinical tool for defining atypical development, pathology, surgical planning, and evaluating treatment outcomes. Despite years of statistical advances in the analysis of complete whole brain data, there has been a limited statistical advance to address the pronounced missingness in many functional imaging studies that use large discovery or small clinical case data. For example, functional magnetic resonance imaging (fMRI) analyses do not always include the entire brain due to image acquisition space limitations and susceptibility artifacts (a loss and spatial distortion of signal that results from a disruption in the magnetic field). The consequence is ‘no data’ or ‘bad data’, respectively. No data occurs when the image acquisition doesn’t cover the whole head which leads to no values. In addition to susceptibility artifacts, bad data can occur across the brain because of motion artifacts. Because statistic maps with applied effect size or significance thresholds do not typically include information about which voxels were omitted from analyses, missing data can result in Type II errors for regions that were not tested. Missing data in fMRI studies can therefore undermine the benefits provided by high quality imaging technology used to generate data testing predictions about brain function.
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引用次数: 7
Calculation of Flows Intensities Transformations in Acyclic Directed Networks 无循环有向网络中流强度变换的计算
Pub Date : 2017-01-01 DOI: 10.4172/2155-6180.1000379
G. Tsitsiashvili
The problem considered in this paper is discussing last year’s sufficiently intensively in different biological journals [1-3]. In Tsitsiashvili [4] a problem of a decomposition of balance equations for flows intensities in queuing networks is solving. Such problem is connecting with calculation of flows intensities of proteins networks. Main idea of this procedure is to find clusters with cyclically equivalent nodes and order them by their maximal distance from input clusters so that direct edges may be only from clusters with smaller to clusters with larger distances. Therefore, it is possible to divide all nodes into sets A0,A1,...,Ap so that every edge of the graph is only from node i ∈ At to node j ∈ Aq, t
本文考虑的问题是在不同的生物学期刊上对去年的问题进行了充分深入的讨论[1-3]。在Tsitsiashvili b[4]中,求解了排队网络中流强度平衡方程的分解问题。这一问题与蛋白质网络流动强度的计算有关。该过程的主要思想是寻找具有循环等效节点的簇,并根据它们与输入簇的最大距离对它们进行排序,以便直接边只能从较小的簇到较大距离的簇。因此,可以将所有节点划分为集合A0,A1,…,Ap使得图的每条边仅从节点i∈At到节点j∈Aq, t
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引用次数: 0
Various Biometric Authentication Techniques: A Review 各种生物识别认证技术综述
Pub Date : 2017-01-01 DOI: 10.4172/2155-6180.1000371
K. Ch
Biometrics refers to metrics related to human characteristics. Biometrics is a realistic authentication used as a form of identification and access control. It is also used to identify individuals in groups that are under surveillance. Biometric identifiers are then measurable, distinctive characteristics used to label and describe individuals. Biometric authenticators are frequently labeled as behavioral as well as physiological characteristics. Physiological characteristics are related to the shape of the body. By utilizing biometrics a man could be distinguished in view of "who she/he is" instead of "what she/he has" (card, token, scratch) or "what she/he knows" (secret key, PIN).In this paper, the fundamental concentrate is on the different biometrics and their applications. Citation: Kalyani CH (2017) Various Biometric Authentication Techniques: A Review. J Biom Biostat 8: 371. doi: 10.4172/2155-6180.1000371
生物计量学是指与人类特征相关的指标。生物识别技术是一种现实的身份验证,用作身份识别和访问控制的一种形式。它也被用来识别受到监视的群体中的个人。生物特征标识符是可测量的、独特的特征,用于标记和描述个体。生物识别认证器经常被标记为行为和生理特征。生理特征与身体的形状有关。通过使用生物识别技术,可以根据“她/他是谁”来区分一个人,而不是“她/他有什么”(卡、令牌、刮)或“她/他知道什么”(密钥、密码)。本文主要介绍了不同的生物识别技术及其应用。引用本文:Kalyani CH(2017)各种生物识别认证技术:综述。[J]中国生物医学工程学报,28(3):371。doi: 10.4172 / 2155 - 6180.1000371
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引用次数: 21
A Machine Learning Approach to Designing Guidelines for Acute Aquatic Toxicity 设计急性水生毒性指南的机器学习方法
Pub Date : 2017-01-01 DOI: 10.4172/2155-6180.1000385
B. Husowitz, R. Sanchez-Arias
A support vector classification wrapper feature elimination approach was used to find the most relevant pairs of molecular features that adequately and accurately can predict acute aquatic toxicity. These pairs were then used to derive chemical thresholds or boundaries between chemical properties for toxic and nontoxic organic chemicals that can be used as a “rule of thumb” to design less toxic chemicals. The most relevant pairs were determined to be: Lowest Unoccupied Molecular Orbital (LUMO) and Aqueous Solubility (QPlogS), Difference between the LUMO and HOMO (dE) and Octonal-Water Partition Coefficient (QPlogo.w), and Difference between the LUMO and HOMO (dE) and Van der Waals surface area of polar nitrogen and oxygen atoms (PSA). Projected hyper planes were constructed for each pair and the following thresholds were found: for Lowest Unoccupied Molecular Orbital (LUMO) and Aqueous Solubility (QPlogS) they roughly correspond to QPlogS>-1 and LUMO>1, and for Octonal-Water Partition Coefficient (QPlogo.w) vs. difference between the LUMO and HOMO (dE) they roughly correspond to QPlogo.w 9. This study shows how a statistical approach such as support vector machines can be applied to the rational design of chemicals with reduced toxicity.
采用支持向量分类包装特征消去方法,寻找最相关的分子特征对,充分准确地预测急性水生毒性。然后使用这些对来推导有毒和无毒有机化学品的化学阈值或化学性质之间的界限,这些阈值或化学性质之间的界限可以用作设计毒性较小化学品的“经验法则”。最相关的对是:最低未占据分子轨道(LUMO)和水溶解度(QPlogS), LUMO和HOMO之间的差异(dE)和八元水分配系数(QPlogo.w), LUMO和HOMO之间的差异(dE)和极性氮氧原子的范德瓦尔斯表面积(PSA)。对每对分子构建了投影超平面,发现了以下阈值:最低未占据分子轨道(LUMO)和水溶解度(QPlogS)的阈值大致对应于QPlogS>-1和LUMO> -1,八元水分配系数(QPlogo.w)与LUMO和HOMO之间的差异(dE)的阈值大致对应于QPlogo。w 9。这项研究表明,如何统计方法,如支持向量机可以应用于化学物质的合理设计与降低毒性。
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引用次数: 4
Marketing Policy that Accelerate Tobacco Use in Bangladesh: A Statistical Investigation 加速孟加拉国烟草使用的营销政策:一项统计调查
Pub Date : 2017-01-01 DOI: 10.4172/2155-6180.1000386
P. Sultana, M. TahidurRahman, D. Roy
Background: Tobacco use is a manmade manner which causes severe chronic diseases and Bangladesh is one of the most tobacco prevalent countries in the world. Advertisement and promotion events may have a big contribution to accelerate this. Therefore, this study aimed to analyze the advertisement and promotion events that encouraged the tobacco user. Data and methods: Secondary data of sample size 9629 collected by the Global Adult Tobacco Survey (GATS), 2010 has been used. Along with descriptive analysis, binary logistic regression has been used to analyze the sociodemographic and economic correlates to be encouraged by marketing policy. Results: The most common site for noticing cigarette, bidi and smokeless tobacco product advertisements was in stores (49.90%, 26.25% and 13.97%). From logistic regression it has been found that rural respondents are 1.17 times more inspired to smoke (OR=1.17, 95% CI=1.06, 1.30) from marketing policy than urban respondents. Female respondents are less inspired to smoke (OR=0.24, 95% CI=0.20, 0.28) than male respondents. Older respondents are less inspired to smoke by marketing policy than younger respondents (OR=0.98, 95% CI=0.98, 0.99). On the other hand, Rural respondents are 1.15 times more likely to be inspired to use smokeless product than urban respondents (OR=1.15, 95% CI=1.02, 1.31). Female respondents are 0.63 times less inspired to use smokeless tobacco product than male respondents (OR=0.63, 95% CI=0.51, 0.77) by marketing policy. Older respondents are less inspired to use smokeless tobacco products by marketing policy than younger respondents (OR=0.99, 95% CI=0.98, 0.99). Conclusion: To reduce tobacco use in Bangladesh, Government, policy makers and research institutions that are working for reduction of tobacco use should pay attention more on young, student and female to advocate more. Also, Government could take action to limit advertisement in selling store.
背景:烟草使用是一种人为方式,会导致严重的慢性疾病,孟加拉国是世界上烟草最普遍的国家之一。广告和促销活动可能会加速这一进程。因此,本研究旨在分析鼓励烟草使用者的广告和促销活动。数据和方法:使用2010年全球成人烟草调查(GATS)收集的9629个样本量的二手数据。随着描述性分析,二元逻辑回归已被用于分析受市场政策鼓励的社会人口和经济相关性。结果:卷烟、bidi和无烟烟草制品广告最常被发现的场所是商店(分别为49.90%、26.25%和13.97%)。从逻辑回归中发现,农村受访者受营销政策的影响吸烟的可能性是城市受访者的1.17倍(OR=1.17, 95% CI=1.06, 1.30)。女性受访者比男性受访者更不愿意吸烟(OR=0.24, 95% CI=0.20, 0.28)。与年轻的受访者相比,年长的受访者较少受到营销政策的激励(OR=0.98, 95% CI=0.98, 0.99)。另一方面,农村受访者使用无烟产品的可能性是城市受访者的1.15倍(OR=1.15, 95% CI=1.02, 1.31)。受营销政策影响,女性受访者使用无烟烟草制品的积极性比男性受访者低0.63倍(OR=0.63, 95% CI=0.51, 0.77)。与年轻受访者相比,年长受访者较少受到营销政策的激励而使用无烟烟草制品(OR=0.99, 95% CI=0.98, 0.99)。结论:为了减少孟加拉国的烟草使用,致力于减少烟草使用的政府、决策者和研究机构应该更多地关注年轻人、学生和女性,进行更多的宣传。此外,政府可以采取行动限制广告在销售商店。
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引用次数: 2
Relationship and Prediction of Body Weight from Morphometric Traits in Maefur Goat Population in Tigray, Northern Ethiopia 埃塞俄比亚北部提格雷地区毛山羊种群形态性状与体重的关系及预测
Pub Date : 2017-01-01 DOI: 10.4172/2155-6180.1000370
Weldeyesus Gebreyowhens Berhe
The study was conducted in Erob district eastern zone of Tigray, Northern Ethiopia to determine the relationship between live weight and linear measurements in Maefur goat population under traditional management system. Data on live body weight, linear body measurement and physical body character were collected from randomly selected 600 (297 male and 303 female goats) and categorized into age group of 04-12, 13-18, 19-24, and 24-35 months equivalent with to 0 PPI, 1 PPI, 2 PPI and 3 ≥ PPI with 82, 87, 134 and 297 animals in each age groups, respectively. The data were analyzed using SPSS software 16.0 version. Descriptive statistics, correlation and regression analysis were used. Heart girth was highly correlated to body weight (r=0.97, P<0.01) and used to predict live body weight with regression equations of y1.04 x-(43.3 ± 0.83), R²0.93 for pooled sex and age. The multiple regression equation for prediction of the live body weight was y=(0.74 HG+0.16 BL+0.18 HW) - 42.8, R2=0.95 for pooled sex and age. It was concluded that, there is variability in body measurements across sex and age indicated that these measurements could be exploited in predicting live body weight. Heart girth was the major body trait used to predict live body weight.
本研究在埃塞俄比亚北部提格雷东部地区的Erob区进行,旨在确定传统管理制度下马富羊种群的活重与线性测量之间的关系。随机选取600只山羊(公山羊297只,母山羊303只),按4-12月龄、13-18月龄、19-24月龄和24-35月龄分为PPI = 0、PPI = 1、PPI = 2和PPI = 3组,每组分别有82只、87只、134只和297只。采用SPSS 16.0版软件对数据进行分析。采用描述性统计、相关分析和回归分析。心围与体重高度相关(r=0.97, P<0.01),用于预测活体重,合并性别和年龄的回归方程为y1.04 x-(43.3±0.83),r²0.93。预测活体重的多元回归方程为y=(0.74 HG+0.16 BL+0.18 HW) - 42.8,合并性别和年龄的R2=0.95。结论是,不同性别和年龄的身体测量值存在差异,表明这些测量值可以用于预测活体重。心围是预测活体重的主要身体特征。
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引用次数: 14
Time Series Analysis on Diabetes Mortality in the United States, 1999- 2015 by Kolmogorov-Zurbenko Filter Kolmogorov-Zurbenko Filter对1999- 2015年美国糖尿病死亡率的时间序列分析
Pub Date : 2017-01-01 DOI: 10.4172/2155-6180.1000384
S. Arndorfer, I. Zurbenko
Kolmogorov-Zurbenko filters can be utilized in the public health context analyzing mortality data. This paper aims to expand upon the robust methodology of the KZ filters and their many applications. As a low-pass filter the KZ filters are proven to be the optimal means of analysis for non-stationary data such as mortality data which usually contains various underlying signals: seasonality, long-term trend, and short-term fluctuations. As diabetes incidence and prevalence increases, the burden of health care cost increases, thus prompting the need to understand patterns underlying adverse events related to diabetes, such as mortality. Increasing incidence and prevalence of diabetes prompts the need for preventative measures and understanding what environmental factors are related to adverse events as a result of diabetes. Diabetes mortality across time analyzed with non-parametric models has not previously been studied, thus this extension to the KZ filters is utilized as a preliminary analysis to address the gap in knowledge of diabetes mortality in the United States. Non-parametric time series analysis methods identify an 8.5-year long-term trend as well as annual seasonality of diabetes mortality. Spectral and time analysis of diabetes mortality introduces the relationship between solar activity and diabetes mortality, which is quantified utilizing the cross-correlation between diabetes mortality and total solar irradiation. The strong correlation between solar activity and diabetes mortality confirms the environmental role related specifically to diabetes mortality.
Kolmogorov-Zurbenko过滤器可用于公共卫生领域分析死亡率数据。本文旨在扩展KZ滤波器的鲁棒方法及其许多应用。作为一种低通滤波器,KZ滤波器被证明是分析非平稳数据(如死亡率数据)的最佳手段,这些数据通常包含各种潜在信号:季节性、长期趋势和短期波动。随着糖尿病发病率和流行率的增加,医疗保健费用的负担也在增加,因此需要了解与糖尿病有关的不良事件(如死亡)的潜在模式。糖尿病发病率和患病率的增加促使人们需要采取预防措施,并了解哪些环境因素与糖尿病引起的不良事件有关。以前没有研究过非参数模型跨时间分析糖尿病死亡率,因此对KZ过滤器的扩展被用作初步分析,以解决美国糖尿病死亡率知识的差距。非参数时间序列分析方法确定了8.5年的长期趋势以及糖尿病死亡率的年度季节性。糖尿病死亡率的光谱和时间分析介绍了太阳活动与糖尿病死亡率之间的关系,利用糖尿病死亡率与太阳总辐照度之间的相互关系对其进行了量化。太阳活动与糖尿病死亡率之间的强烈相关性证实了环境对糖尿病死亡率的特殊影响。
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引用次数: 2
A Note on Reporting P-Value in Medical Research 关于医学研究中p值报告的说明
Pub Date : 2016-12-20 DOI: 10.4172/2155-6180.1000328
P. Marimuthu
Marimuthu P* Department of Statistics, National Institute of Health and Family Welfare, New Delhi, India *Corresponding author: Marimuthu P, Department of Statistics, National Institute of Health and Family Welfare, India, Tel: +91-080-26995115; E-mail: p_marimuthu@hotmail.com Received date: October 31, 2016; Accepted date: December 15, 2016; Published date: December 20, 2016 Copyright: © 2016 Marimuthu P. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Citation: Marimuthu P (2016) A Note on Reporting P-Value in Medical Research. J Biom Biostat 7: 328. doi:10.4172/2155-6180.1000328
通讯作者:Marimuthu P,印度国家卫生和家庭福利研究所统计部,印度,电话:+91-080-26995115;邮箱:p_marimuthu@hotmail.com收稿日期:2016年10月31日;录用日期:2016年12月15日;版权所有:©2016 Marimuthu P.这是一篇根据知识共享署名许可条款发布的开放获取文章,该许可允许在任何媒体上不受限制地使用、分发和复制,前提是要注明原作者和来源。引用本文:Marimuthu P (2016) A Note on Reporting P- value in Medical Research。[J]中国生物医学工程学报,7(3):393。doi: 10.4172 / 2155 - 6180.1000328
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引用次数: 0
Intelligence and Early Mastery of the Reading Skill 智力和阅读技能的早期掌握
Pub Date : 2016-12-20 DOI: 10.4172/2155-6180.1000327
A. Michaud
Summary overview of intelligence development in young children coinciding with neocortex verbal areas development by means of mastery of the reading skill and of the state of children literacy development in the world.
幼儿智力发展与新皮层语言区发展的关系:阅读技能的掌握和世界儿童读写能力发展的现状。
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引用次数: 2
期刊
Journal of biometrics & biostatistics
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