A. Krsman, Branislava Baturan, S. Bulatović, D. Petrovic, Ksenija Antic-Trifunovic, D. Stajic
Introduction. Uterocutaneous fistula is a rare complication of cesarean section which is challenging to diagnose and treat. The aim of this paper is to present a case of uterocutaneous fistula in order to contribute to the literature and help in the therapy and diagnosis of this rare complication. Case Report. A 29-year-old patient was referred to our clinic two months after her second cesarean section. The immediate postpartum course was complicated by endometritis treated with antibiotic therapy. At the time of admission, she was afebrile, without complaints other than a 2 cm long wound dehiscence on the anterior abdominal wall. The uterocutaneous fistula was confirmed by injecting methylene blue through the dehiscence on the anterior abdominal wall, which then spread into the vagina through the cervix. After laboratory tests, ultrasound and clinical examination, the patient underwent surgery. A total excision of the fistula was performed by laparotomy. Histopathological findings confirmed the diagnosis of uterocutaneous fistula. The postoperative recovery was uneventful. At the follow-up examination, three months after surgery, the patient had no complaints; the menstrual cycles were normal, as well as the transvaginal ultrasound findings. Conclusion. Uterocutaneous fistula is a rare complication following cesarean section. Timely identification of the fistula, its complete resection, and adequate antibiotic therapy in case of infection are necessary.
{"title":"Uterocutaneous fistula after cesarean section − a rare diagnosis not to be missed - a case report","authors":"A. Krsman, Branislava Baturan, S. Bulatović, D. Petrovic, Ksenija Antic-Trifunovic, D. Stajic","doi":"10.2298/mpns2212374k","DOIUrl":"https://doi.org/10.2298/mpns2212374k","url":null,"abstract":"Introduction. Uterocutaneous fistula is a rare complication of cesarean section which is challenging to diagnose and treat. The aim of this paper is to present a case of uterocutaneous fistula in order to contribute to the literature and help in the therapy and diagnosis of this rare complication. Case Report. A 29-year-old patient was referred to our clinic two months after her second cesarean section. The immediate postpartum course was complicated by endometritis treated with antibiotic therapy. At the time of admission, she was afebrile, without complaints other than a 2 cm long wound dehiscence on the anterior abdominal wall. The uterocutaneous fistula was confirmed by injecting methylene blue through the dehiscence on the anterior abdominal wall, which then spread into the vagina through the cervix. After laboratory tests, ultrasound and clinical examination, the patient underwent surgery. A total excision of the fistula was performed by laparotomy. Histopathological findings confirmed the diagnosis of uterocutaneous fistula. The postoperative recovery was uneventful. At the follow-up examination, three months after surgery, the patient had no complaints; the menstrual cycles were normal, as well as the transvaginal ultrasound findings. Conclusion. Uterocutaneous fistula is a rare complication following cesarean section. Timely identification of the fistula, its complete resection, and adequate antibiotic therapy in case of infection are necessary.","PeriodicalId":87940,"journal":{"name":"Calcutta medical review","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82981158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Golubović, S. Slavković, Z. Gajic, Aleksandra Becagul
Introduction. Disorders of cognitive functioning in patients with psychosis can manifest in different domains. The disorders vary depending on the severity, from mild to severe, and on the severity of symptoms within the underlying disease. The aim of this study was to examine the possibility of using the Audio Recorded Cognitive Screen in patients with schizophrenia. Material and Methods. The study included a total of 61 subjects divided into two groups: 31 subjects with schizophrenia and 30 healthy controls. All subjects completed the Audio Recorded Cognitive Screen to assess the cognitive status in five domains of cognitive functioning. Results. The Audio Recorded Cognitive Screen showed a good reliability index (? = 0.85). Multivariate analysis of variance confirmed the differences between the two groups in all examined cognitive domains (F (6.53) = 26.719, p < .001). The partial eta squared results were as follows: object naming 0.159; immediate recall 0.531; delayed recall 0.585; visuospatial functions 0.334; attention 0.644; and verbal fluency 0.590. These results indicated significant differences between the two groups. Conclusion. The Audio Recorded Cognitive Screen is a feasible tool for the detection of neurocognitive impairment in individuals with schizophrenia. However, it is necessary to conduct further research in larger samples and use additional assessment instruments in this population.
介绍。精神病患者的认知功能障碍可以表现在不同的领域。这些疾病根据严重程度，从轻微到严重，以及潜在疾病的症状严重程度而有所不同。本研究的目的是探讨在精神分裂症患者中使用录音认知屏幕的可能性。材料和方法。该研究共包括61名受试者，分为两组:31名精神分裂症患者和30名健康对照者。所有被试均完成了认知录音测试，以评估他们在五个认知功能领域的认知状态。结果。录音认知屏幕显示出良好的可靠性指数(?= 0.85)。多因素方差分析证实了两组在所有检查的认知领域的差异(F (6.53) = 26.719, p < 0.001)。偏eta平方结果如下:对象命名0.159;立即召回0.531;延迟召回0.585;视觉空间函数0.334;注意0.644;语言流利度0.590。这些结果表明两组之间存在显著差异。结论。录音认知屏幕是一种可行的工具，用于检测精神分裂症患者的神经认知障碍。然而，有必要在更大的样本中进行进一步的研究，并在这一人群中使用额外的评估工具。
{"title":"The audio recorded cognitive screen for brief screening of cognitive impairment in patients with psychosis: A pilot study","authors":"B. Golubović, S. Slavković, Z. Gajic, Aleksandra Becagul","doi":"10.2298/mpns2202026g","DOIUrl":"https://doi.org/10.2298/mpns2202026g","url":null,"abstract":"Introduction. Disorders of cognitive functioning in patients with psychosis can manifest in different domains. The disorders vary depending on the severity, from mild to severe, and on the severity of symptoms within the underlying disease. The aim of this study was to examine the possibility of using the Audio Recorded Cognitive Screen in patients with schizophrenia. Material and Methods. The study included a total of 61 subjects divided into two groups: 31 subjects with schizophrenia and 30 healthy controls. All subjects completed the Audio Recorded Cognitive Screen to assess the cognitive status in five domains of cognitive functioning. Results. The Audio Recorded Cognitive Screen showed a good reliability index (? = 0.85). Multivariate analysis of variance confirmed the differences between the two groups in all examined cognitive domains (F (6.53) = 26.719, p < .001). The partial eta squared results were as follows: object naming 0.159; immediate recall 0.531; delayed recall 0.585; visuospatial functions 0.334; attention 0.644; and verbal fluency 0.590. These results indicated significant differences between the two groups. Conclusion. The Audio Recorded Cognitive Screen is a feasible tool for the detection of neurocognitive impairment in individuals with schizophrenia. However, it is necessary to conduct further research in larger samples and use additional assessment instruments in this population.","PeriodicalId":87940,"journal":{"name":"Calcutta medical review","volume":"546 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91252979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Vujic, Željko Zečević, Marija K Simic, B. Gobeljic, E. Lazic, G. Samardžija, O. Šerbić
The first allogeneic identical sibling donor hematopoietic stem cell transplantation at the Institute for Mother and Child Health Care of Serbia ?Dr. Vukan Cupic? (Institute) was performed in the seventies of the last century. Almost twenty years later, the first allogeneic transplant from sibling haploidentical donor was performed in an infant suffering from severe combined immunodeficiency. After several years of efforts, the bone marrow transplant unit was opened in April 1997 at the Institute. Over the 25 years, the transplant team performed 360 hematopoietic stem cell transplantations, 175 autologous and 185 allogeneic (103 from identical sibling donor, 43 from haploidentical sibling donor, 36 from matched unrelated donor, 2 from identical sibling cord blood and 1 from unrelated identical cord blood).
{"title":"Pediatric hematopoietic stem cell transplantation in Serbia - 25 years of experience","authors":"D. Vujic, Željko Zečević, Marija K Simic, B. Gobeljic, E. Lazic, G. Samardžija, O. Šerbić","doi":"10.2298/mpns22s1050v","DOIUrl":"https://doi.org/10.2298/mpns22s1050v","url":null,"abstract":"The first allogeneic identical sibling donor hematopoietic stem cell transplantation at the Institute for Mother and Child Health Care of Serbia ?Dr. Vukan Cupic? (Institute) was performed in the seventies of the last century. Almost twenty years later, the first allogeneic transplant from sibling haploidentical donor was performed in an infant suffering from severe combined immunodeficiency. After several years of efforts, the bone marrow transplant unit was opened in April 1997 at the Institute. Over the 25 years, the transplant team performed 360 hematopoietic stem cell transplantations, 175 autologous and 185 allogeneic (103 from identical sibling donor, 43 from haploidentical sibling donor, 36 from matched unrelated donor, 2 from identical sibling cord blood and 1 from unrelated identical cord blood).","PeriodicalId":87940,"journal":{"name":"Calcutta medical review","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84196648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction. Acute lymphoblastic leukemia is a malignant disease characterized by the proliferation of precursor B-cells, Tcells or less often, precursors of NK-cells. B-cell acute lymphoblastic leukemia is more common in patients >60 years of age compared to patients <60 years of age (89% vs. 66%), and cytogenetic abnormalities such as t(9;22) (Ph+) are more common in older than younger patients (36% against 19%). Elderly patients often have a poor status and comorbidities, so poor disease outcome is more common. Clinical and biological features. B cell acute lymphoblastic leukemia is more common in patients >60 years of age compared to patients <60 years of age (89% vs 66%) and cytogenetic abnormalities such as t(9;22) are more common in older vs. younger (36% vs. 19%). Therapy. The elderly and patients with comorbidities require less intensive therapy, based on corticosteroids, vincristine and asparaginase, while avoiding anthracyclines and alkylating agents, due to the high mortality associated with treatment. For ?unfit? patients with Ph-positive acute lymphoblastic leukemia, tyrosine kinase inhibitors with reduced-intensity chemotherapy or corticosteroids alone are recommended. For t(9;22) negative patients, low-dose corticosteroid chemotherapy with or without immunotherapy is recommended. For patients with T-cell acute lymphoblastic leukemia, chemotherapy with venetoclax may be an option. Conclusion. The introduction of targeted therapy has changed treatment options in acute lymphoblastic leukemia. For elderly patients, targeted therapy is a necessary modality since standard chemotherapy leads to a poor outcome due to its toxicity and ineffectiveness.
{"title":"Treatment of patients with acute lymphoblastic leukemia who are not suitable for high-dose chemotherapy and hematopoietic stem cell transplantation","authors":"N. Govedarović","doi":"10.2298/mpns22s1019g","DOIUrl":"https://doi.org/10.2298/mpns22s1019g","url":null,"abstract":"Introduction. Acute lymphoblastic leukemia is a malignant disease characterized by the proliferation of precursor B-cells, Tcells or less often, precursors of NK-cells. B-cell acute lymphoblastic leukemia is more common in patients >60 years of age compared to patients <60 years of age (89% vs. 66%), and cytogenetic abnormalities such as t(9;22) (Ph+) are more common in older than younger patients (36% against 19%). Elderly patients often have a poor status and comorbidities, so poor disease outcome is more common. Clinical and biological features. B cell acute lymphoblastic leukemia is more common in patients >60 years of age compared to patients <60 years of age (89% vs 66%) and cytogenetic abnormalities such as t(9;22) are more common in older vs. younger (36% vs. 19%). Therapy. The elderly and patients with comorbidities require less intensive therapy, based on corticosteroids, vincristine and asparaginase, while avoiding anthracyclines and alkylating agents, due to the high mortality associated with treatment. For ?unfit? patients with Ph-positive acute lymphoblastic leukemia, tyrosine kinase inhibitors with reduced-intensity chemotherapy or corticosteroids alone are recommended. For t(9;22) negative patients, low-dose corticosteroid chemotherapy with or without immunotherapy is recommended. For patients with T-cell acute lymphoblastic leukemia, chemotherapy with venetoclax may be an option. Conclusion. The introduction of targeted therapy has changed treatment options in acute lymphoblastic leukemia. For elderly patients, targeted therapy is a necessary modality since standard chemotherapy leads to a poor outcome due to its toxicity and ineffectiveness.","PeriodicalId":87940,"journal":{"name":"Calcutta medical review","volume":"294 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90384252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tatjana Nikolov, A. Savić, T. Janković, Marina Maksimovic-Simovic, K. Boskovic
Introduction. Horizontal therapy is the only electrotherapy modality for the treatment of osteoarthritis that has a simultaneous bioelectrical and biochemical, effect on deep and superficial joint tissues. The objective of this report was to provide evidence of efficacy of horizontal therapy in a patient suffering from lumbar spine osteoarthritis. Case report. A 70-year-old female patient was admitted to the hospital due to severe low back pain with radiating pain in both legs followed by tingling in left leg. The patient has had this painful condition since 2010. Physical examination revealed a reduction of the range of motion of the lumbar spine followed by spasm of the paraspinal musculature. Deep tendon reflexes of the lower limbs were 2+ bilaterally, except right patellar reflex which was absent. She had hypoesthesia in L4, L5 and S1 dermatome of the left leg and no motor deficits were noted. Radiographic evaluation showed multilevel degenerative changes of the lumbar spine. The patient was prescribed medication, physical and exercise therapy. She underwent horizontal therapy for lumbar spine with a frequency oscillating between 4357 and 12127 hertz. The patient had a total of 15 treatments, 5 per week and each lasted 30 minutes. Conclusion. In a patient with osteoarthritis of the spine, horizontal therapy has proved to be an effective modality of physical therapy leading to pain relief and functional improvement. Additional clinical research is needed for confirming its effectiveness on a larger sample, to define optimal parameters of the application and indication areas.
{"title":"The efficacy of a modality of physical therapy in the treatment of osteoarthritis of the spine - a case report of a patient treated with horizontal therapy","authors":"Tatjana Nikolov, A. Savić, T. Janković, Marina Maksimovic-Simovic, K. Boskovic","doi":"10.2298/mpns22s2053n","DOIUrl":"https://doi.org/10.2298/mpns22s2053n","url":null,"abstract":"Introduction. Horizontal therapy is the only electrotherapy modality for the treatment of osteoarthritis that has a simultaneous bioelectrical and biochemical, effect on deep and superficial joint tissues. The objective of this report was to provide evidence of efficacy of horizontal therapy in a patient suffering from lumbar spine osteoarthritis. Case report. A 70-year-old female patient was admitted to the hospital due to severe low back pain with radiating pain in both legs followed by tingling in left leg. The patient has had this painful condition since 2010. Physical examination revealed a reduction of the range of motion of the lumbar spine followed by spasm of the paraspinal musculature. Deep tendon reflexes of the lower limbs were 2+ bilaterally, except right patellar reflex which was absent. She had hypoesthesia in L4, L5 and S1 dermatome of the left leg and no motor deficits were noted. Radiographic evaluation showed multilevel degenerative changes of the lumbar spine. The patient was prescribed medication, physical and exercise therapy. She underwent horizontal therapy for lumbar spine with a frequency oscillating between 4357 and 12127 hertz. The patient had a total of 15 treatments, 5 per week and each lasted 30 minutes. Conclusion. In a patient with osteoarthritis of the spine, horizontal therapy has proved to be an effective modality of physical therapy leading to pain relief and functional improvement. Additional clinical research is needed for confirming its effectiveness on a larger sample, to define optimal parameters of the application and indication areas.","PeriodicalId":87940,"journal":{"name":"Calcutta medical review","volume":"169 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89021867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Marjanovic, T. Džopalić, M. Kostic, M. Lazarević, Z. Stojanoski, B. Bonaci-Nikolic
After infections, malignancies, lymphomas especially, are the second most frequent cause of death in patients with inborn errors of immunity. Factors predetermining the appearance and aggressiveness of lymphomas include gene defects, defects of immune surveillance and regulation as well as infections with oncogenic viruses. Aggressive non-Hodgkin lymphomas, mostly diffuse large B-cell and Bukit subtypes are predominant in deoxyribonucleic acid repair defects, while Hodgkin lymphoma becomes equally present in patients with defects of immune regulation. Marginal zone and mucosa-associated lymphoid tissue lymphomas, appear to be frequent in defects of antibody production, especially in patients with common variable immune deficiency. The prevalence of Epstein-Barr virus may vary within entities, but there is no entity without at least a few cases of lymphoma and Epstein-Barr virus co-infection. Standard treatment of lymphomas associated with deoxyribonucleic acid repair defects and severe combined deficiencies, is stem cell transplantation. Lymphomas in inborn errors of immunity with a less severe clinical presentation, should be treated with immunochemotherapy and monoclonal antibodies (Brentuximab, Rituximab) wherever feasible. There is no data about the usefulness of checkpoint inhibitors, bi-specific antibodies and T-cells with chimeric antigen receptor. Allogeneic stem cell transplantation represents a major indication for treatment of relapse/refractory lymphomas in any inborn error of immunity. Potential benefit of therapy with Chimeric antigen receptor Natural-killer cells in lymphomas associated with inborn errors of immunity, remains to be seen in future studies.
{"title":"From inborn errors of immunity to lymphoma: A hematologist’s point of view","authors":"G. Marjanovic, T. Džopalić, M. Kostic, M. Lazarević, Z. Stojanoski, B. Bonaci-Nikolic","doi":"10.2298/mpns22s1066m","DOIUrl":"https://doi.org/10.2298/mpns22s1066m","url":null,"abstract":"After infections, malignancies, lymphomas especially, are the second most frequent cause of death in patients with inborn errors of immunity. Factors predetermining the appearance and aggressiveness of lymphomas include gene defects, defects of immune surveillance and regulation as well as infections with oncogenic viruses. Aggressive non-Hodgkin lymphomas, mostly diffuse large B-cell and Bukit subtypes are predominant in deoxyribonucleic acid repair defects, while Hodgkin lymphoma becomes equally present in patients with defects of immune regulation. Marginal zone and mucosa-associated lymphoid tissue lymphomas, appear to be frequent in defects of antibody production, especially in patients with common variable immune deficiency. The prevalence of Epstein-Barr virus may vary within entities, but there is no entity without at least a few cases of lymphoma and Epstein-Barr virus co-infection. Standard treatment of lymphomas associated with deoxyribonucleic acid repair defects and severe combined deficiencies, is stem cell transplantation. Lymphomas in inborn errors of immunity with a less severe clinical presentation, should be treated with immunochemotherapy and monoclonal antibodies (Brentuximab, Rituximab) wherever feasible. There is no data about the usefulness of checkpoint inhibitors, bi-specific antibodies and T-cells with chimeric antigen receptor. Allogeneic stem cell transplantation represents a major indication for treatment of relapse/refractory lymphomas in any inborn error of immunity. Potential benefit of therapy with Chimeric antigen receptor Natural-killer cells in lymphomas associated with inborn errors of immunity, remains to be seen in future studies.","PeriodicalId":87940,"journal":{"name":"Calcutta medical review","volume":"398 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91452218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Zvekic-Svorcan, K. Boskovic, T. Janković, R. Krasnik, Natasa Igic, I. Minaković
Introduction. Osteoporosis is a metabolic bone disease characterized by reduced bone mineral density and damage to the bone microarchitecture, which leads to bone fragility, thus increasing the risk of osteoporotic fractures. While different diagnostic methods can be employed for detecting bone mineral density decrement in a timely manner, dual energy X-ray absorptiometry remains the gold standard in research and clinical practice. Bone mineral density estimation methods. Osteoporosis can be diagnosed through conventional radiography, quantitative ultrasonography, quantitative computed tomography, and magnetic resonance. Nonetheless, dual energy X-ray absorptiometry is the gold standard in the diagnosis of osteoporosis on which further treatment and monitoring are based. The dual energy X-ray absorptiometry apparatus is equipped with the Fracture Risk Assessment Tool, which estimates the 10- year probability of a major fracture and hip fracture due to osteoporosis. The use and interpretation of osteoporosis diagnostic evaluation modalities is based on the International Society for Clinical Densitometry guidelines for diagnosing osteoporosis in adults and children. According to the International Society for Clinical Densitometry recommendations, the aforementioned quantitative visualization modalities should be used alongside laboratory analyses of bone metabolism markers to supplement diagnostics and monitor treatment efficacy in patients suffering from osteoporosis. Conclusion. Assessment of risk factors and early diagnosis are prerequisites for timely treatment and effective monitoring, which is necessary for arresting the progression of bone mineral density loss and preventing the occurrence of osteoporotic fractures.
{"title":"Diagnosis of osteoporosis and prevention of osteoporotic fractures","authors":"J. Zvekic-Svorcan, K. Boskovic, T. Janković, R. Krasnik, Natasa Igic, I. Minaković","doi":"10.2298/mpns22s2013z","DOIUrl":"https://doi.org/10.2298/mpns22s2013z","url":null,"abstract":"Introduction. Osteoporosis is a metabolic bone disease characterized by reduced bone mineral density and damage to the bone microarchitecture, which leads to bone fragility, thus increasing the risk of osteoporotic fractures. While different diagnostic methods can be employed for detecting bone mineral density decrement in a timely manner, dual energy X-ray absorptiometry remains the gold standard in research and clinical practice. Bone mineral density estimation methods. Osteoporosis can be diagnosed through conventional radiography, quantitative ultrasonography, quantitative computed tomography, and magnetic resonance. Nonetheless, dual energy X-ray absorptiometry is the gold standard in the diagnosis of osteoporosis on which further treatment and monitoring are based. The dual energy X-ray absorptiometry apparatus is equipped with the Fracture Risk Assessment Tool, which estimates the 10- year probability of a major fracture and hip fracture due to osteoporosis. The use and interpretation of osteoporosis diagnostic evaluation modalities is based on the International Society for Clinical Densitometry guidelines for diagnosing osteoporosis in adults and children. According to the International Society for Clinical Densitometry recommendations, the aforementioned quantitative visualization modalities should be used alongside laboratory analyses of bone metabolism markers to supplement diagnostics and monitor treatment efficacy in patients suffering from osteoporosis. Conclusion. Assessment of risk factors and early diagnosis are prerequisites for timely treatment and effective monitoring, which is necessary for arresting the progression of bone mineral density loss and preventing the occurrence of osteoporotic fractures.","PeriodicalId":87940,"journal":{"name":"Calcutta medical review","volume":"165 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91461571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dajana Dedic, Aleksandra Kovac, S. Popović-Petrović, Ivana Zelic-Kozomora
Introduction. The psychological status of patients with breast cancer is often compromised as a result of chronic exposure to negative emotions and psychological distress after the diagnosis of a malignant disease and conditions such as depression and anxiety may have a direct impact on the functional wellbeing of breast cancer patients. The aim of this study was to examine whether depression affects the functional well-being of breast cancer patients. Material and Methods. This crosssectional study was conducted in 2021 and it included 71 breast cancer patients treated at the Department of Physical Medicine and Rehabilitation of the Oncology Institute of Vojvodina at the time of examination. The depression subscale of the Serbian version of the Depression, Anxiety and Stress Scale 21, assessing the degree of depression was used to assess depressive symptoms in the participants. The functional well-being was assessed using the Functional Well-Being subscale of the questionnaire for the Functional Assessment of Cancer Therapy - Breast. Results. A statistically significant correlation was found between depression and functional well-being (r = - 0.438, p < 0.001) of the examined patients. The results of the regression analysis showed that the F model was significant (F (1.69) = 16.366; p < 0.001) and showed 19.2% of the variance. Depression has a significant impact on the functional well-being of breast cancer patients (? = - 438, t = - 4.045, p < 0.001). Conclusion. Through a multidisciplinary approach, it is important to simultaneously functionally train breast cancer patients, but also to implement timely psychological support and rehabilitation.
介绍。在诊断出恶性疾病后，由于长期暴露于负面情绪和心理困扰，乳腺癌患者的心理状态往往受到损害，抑郁和焦虑等状况可能对乳腺癌患者的功能健康产生直接影响。这项研究的目的是研究抑郁症是否会影响乳腺癌患者的功能健康。材料和方法。这项横断面研究于2021年进行，其中包括在检查时在伏伊伏丁那肿瘤研究所物理医学和康复部接受治疗的71名乳腺癌患者。塞尔维亚版抑郁、焦虑和压力量表21的抑郁子量表评估抑郁程度，用于评估参与者的抑郁症状。功能幸福感采用乳腺癌治疗功能评估问卷的功能幸福感子量表进行评估。结果。被检查患者的抑郁与功能幸福感之间存在统计学显著相关(r = - 0.438, p < 0.001)。回归分析结果显示，F模型显著(F (1.69) = 16.366;P < 0.001)，方差为19.2%。抑郁症对乳腺癌患者的功能幸福感有显著影响(?= - 438, t = - 4.045, p < 0.001)。结论。通过多学科的方法，在对乳腺癌患者进行功能训练的同时，还要及时实施心理支持和康复。
{"title":"Effects of depression on the functional well-being of patients with breast cancer","authors":"Dajana Dedic, Aleksandra Kovac, S. Popović-Petrović, Ivana Zelic-Kozomora","doi":"10.2298/mpns2210290d","DOIUrl":"https://doi.org/10.2298/mpns2210290d","url":null,"abstract":"Introduction. The psychological status of patients with breast cancer is often compromised as a result of chronic exposure to negative emotions and psychological distress after the diagnosis of a malignant disease and conditions such as depression and anxiety may have a direct impact on the functional wellbeing of breast cancer patients. The aim of this study was to examine whether depression affects the functional well-being of breast cancer patients. Material and Methods. This crosssectional study was conducted in 2021 and it included 71 breast cancer patients treated at the Department of Physical Medicine and Rehabilitation of the Oncology Institute of Vojvodina at the time of examination. The depression subscale of the Serbian version of the Depression, Anxiety and Stress Scale 21, assessing the degree of depression was used to assess depressive symptoms in the participants. The functional well-being was assessed using the Functional Well-Being subscale of the questionnaire for the Functional Assessment of Cancer Therapy - Breast. Results. A statistically significant correlation was found between depression and functional well-being (r = - 0.438, p < 0.001) of the examined patients. The results of the regression analysis showed that the F model was significant (F (1.69) = 16.366; p < 0.001) and showed 19.2% of the variance. Depression has a significant impact on the functional well-being of breast cancer patients (? = - 438, t = - 4.045, p < 0.001). Conclusion. Through a multidisciplinary approach, it is important to simultaneously functionally train breast cancer patients, but also to implement timely psychological support and rehabilitation.","PeriodicalId":87940,"journal":{"name":"Calcutta medical review","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83537773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sonja Sedlarevic, Bozidar Dejanovic, Z. Savic, Bojan Vuković, Vanja Calic, M. Lekin
Introduction. Purple urine bag syndrome is a condition where the urinary catheter bag turns purple as a result of the interaction between bacteria, urine and components of the urine bag. It appears in a certain group of patients with the following risk factors: urinary tract infection, older age, long-term indwelling urinary catheter, constipation, chronic kidney disease. Case Report. Two patients with purple urine bag syndrome are presented. The first patient, a 66-year-old man, was hospitalized due to decompensation of alcoholic liver cirrhosis. A urinary catheter was placed on admission, and on the fourteenth day of hospitalization, a purple discoloration of the urine in the urinary bag was noticed. Multidrug-resistant Proteus mirabilis and Enterococcus faecalis were isolated by microbiological analysis of urine. The second patient was a 92-year-old man, hospitalized for acute gastrointestinal bleeding in the form of hematochezia, with an indwelling urinary catheter and a history of a prostate cancer surgery. On the third hospital day, a purple content in the urinary catheter bag was detected and Klebsiella pneumoniae and Morganella morganii were confirmed by bacteriological analysis. Both patients were without clinical and laboratory signs of acute infection. In both cases, the urinary catheter was replaced and ceftriaxone was administered empirically. Conclusion. Current guidelines for purple urine bag syndrome recommend catheter replacement and empiric antibiotic therapy. In clinical practice, it is necessary to emphasize that urine sampling for bacteriological analysis is performed only after replacing the catheter, in order to establish the exact etiology of the syndrome and radical use of antibiotics.
{"title":"Purple urine bag syndrome - a sign of urinary tract infection, or just of urinary catheter bacterial colonization: A case report","authors":"Sonja Sedlarevic, Bozidar Dejanovic, Z. Savic, Bojan Vuković, Vanja Calic, M. Lekin","doi":"10.2298/mpns2210301s","DOIUrl":"https://doi.org/10.2298/mpns2210301s","url":null,"abstract":"Introduction. Purple urine bag syndrome is a condition where the urinary catheter bag turns purple as a result of the interaction between bacteria, urine and components of the urine bag. It appears in a certain group of patients with the following risk factors: urinary tract infection, older age, long-term indwelling urinary catheter, constipation, chronic kidney disease. Case Report. Two patients with purple urine bag syndrome are presented. The first patient, a 66-year-old man, was hospitalized due to decompensation of alcoholic liver cirrhosis. A urinary catheter was placed on admission, and on the fourteenth day of hospitalization, a purple discoloration of the urine in the urinary bag was noticed. Multidrug-resistant Proteus mirabilis and Enterococcus faecalis were isolated by microbiological analysis of urine. The second patient was a 92-year-old man, hospitalized for acute gastrointestinal bleeding in the form of hematochezia, with an indwelling urinary catheter and a history of a prostate cancer surgery. On the third hospital day, a purple content in the urinary catheter bag was detected and Klebsiella pneumoniae and Morganella morganii were confirmed by bacteriological analysis. Both patients were without clinical and laboratory signs of acute infection. In both cases, the urinary catheter was replaced and ceftriaxone was administered empirically. Conclusion. Current guidelines for purple urine bag syndrome recommend catheter replacement and empiric antibiotic therapy. In clinical practice, it is necessary to emphasize that urine sampling for bacteriological analysis is performed only after replacing the catheter, in order to establish the exact etiology of the syndrome and radical use of antibiotics.","PeriodicalId":87940,"journal":{"name":"Calcutta medical review","volume":"87 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85747933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nataša Puškar, Milica Puskar, P. Vucinic, Stojan Ivić, D. Petrović
Introduction. Class III malocclusions are characterized by a more prominent lower jaw compared to the upper jaw and a Class III skeletal and dentoalveolar relationship according to Angle. In the scientific literature, there is a small amount of data on the morphological characteristics of malocclusion in different populations, so there is a justified need to examine the morphological characteristics of Class III malocclusion in the population of Vojvodina. The aim of this study was to determine the morphological characteristics of Class III malocclusions, to compare them with the average values found in the scientific literature, and to determine the correlation between the examined parameters of the upper and lower jaw. Material and Methods. This retrospective study included subjects with Class III dentoalveolar malocclusion treated at the Dentistry Clinic of Vojvodina in Novi Sad. The method of random selection was used to select 50 study models. The data were statistically processed with a significance level of p < 0.05. Results. The obtained results indicate that the sum of crown width of the mandibular incisors, the length of the mandibular dental arch, and the mandibular apical base in subjects with Class III malocclusion are higher than the average values in the general population. The values of the posterior width of the maxillary dental arch in the examined group are lower compared to the average values in the general population. Conclusion. Subjects with Class III malocclusion present with a greater mandibular dental arch in regard to the maxillary dental arch.
{"title":"Determination of dentoalveolar parameters in patients with progenia","authors":"Nataša Puškar, Milica Puskar, P. Vucinic, Stojan Ivić, D. Petrović","doi":"10.2298/mpns2210279p","DOIUrl":"https://doi.org/10.2298/mpns2210279p","url":null,"abstract":"Introduction. Class III malocclusions are characterized by a more prominent lower jaw compared to the upper jaw and a Class III skeletal and dentoalveolar relationship according to Angle. In the scientific literature, there is a small amount of data on the morphological characteristics of malocclusion in different populations, so there is a justified need to examine the morphological characteristics of Class III malocclusion in the population of Vojvodina. The aim of this study was to determine the morphological characteristics of Class III malocclusions, to compare them with the average values found in the scientific literature, and to determine the correlation between the examined parameters of the upper and lower jaw. Material and Methods. This retrospective study included subjects with Class III dentoalveolar malocclusion treated at the Dentistry Clinic of Vojvodina in Novi Sad. The method of random selection was used to select 50 study models. The data were statistically processed with a significance level of p < 0.05. Results. The obtained results indicate that the sum of crown width of the mandibular incisors, the length of the mandibular dental arch, and the mandibular apical base in subjects with Class III malocclusion are higher than the average values in the general population. The values of the posterior width of the maxillary dental arch in the examined group are lower compared to the average values in the general population. Conclusion. Subjects with Class III malocclusion present with a greater mandibular dental arch in regard to the maxillary dental arch.","PeriodicalId":87940,"journal":{"name":"Calcutta medical review","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81007922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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