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A retrospective analysis of T1 erector spinae plane blocks compared to multimodal pain management alone in first rib resections for patients with thoracic outlet syndrome. 回顾性分析T1竖肌脊柱平面阻滞与单纯多模式疼痛管理在胸廓出口综合征患者第一肋骨切除术中的比较。
Q3 Medicine Pub Date : 2025-07-30 eCollection Date: 2025-01-01 DOI: 10.1080/08998280.2025.2537518
Richard Cook, Daniel C Gunn, Richard P Dutton, Gregory J Pearl, Bradley R Grimsley, Saravanan Ramamoorthy

Background: Erector spinae plane blocks (ESPB), a new and increasingly popular technique for controlling thoracic pain, have typically been performed around the T5 level. Using a T1 ESPB for first rib resections in patients with thoracic outlet syndrome (TOS) might offer better pain control relative to the current standard of intravenous multimodal pain management alone.

Methods: All first rib resections for patients with TOS during an 18-month period (n = 380) were analyzed. In-hospital opioid consumption, the number of patients discharged with an opioid prescription, and hospital admission length were compared between patients receiving ESPBs and multimodal pain management alone.

Results: ESPB patients received 26.18% less morphine milligram equivalents on postoperative day 1 (P < 0.001) and were 13.23% less likely to be discharged with an opioid prescription (P < 0.001). Admission length between the two groups was not meaningfully different (P = 0.84).

Conclusion: T1 ESPBs offer effective regional pain control for TOS patients undergoing first rib resections while mitigating the potential for opioid dependence and abuse. No increased risk of complication with ESPB was observed relative to multimodal pain management alone.

背景:竖脊机脊柱平面阻滞(ESPB)是一种控制胸椎疼痛的新技术,越来越受欢迎,通常在T5水平周围进行。在胸廓出口综合征(TOS)患者的第一肋骨切除术中使用T1 ESPB可能比目前的静脉多模式疼痛管理标准提供更好的疼痛控制。方法:对18个月内所有TOS患者的第一肋骨切除术(n = 380)进行分析。比较院内阿片类药物消耗、阿片类药物处方出院的患者数量和住院时间,比较接受体外刺激疗法和单独接受多模式疼痛治疗的患者。结果:ESPB患者术后第1天吗啡毫克当量减少26.18% (P P P = 0.84)。结论:T1 espb可有效控制TOS第一肋骨切除术患者的局部疼痛,同时减轻阿片类药物依赖和滥用的可能性。与单独的多模式疼痛管理相比,ESPB的并发症风险没有增加。
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引用次数: 0
Rosacea and seborrheic dermatitis: a retrospective cohort study. 酒渣鼻和脂溢性皮炎:一项回顾性队列研究。
Q3 Medicine Pub Date : 2025-07-30 eCollection Date: 2025-01-01 DOI: 10.1080/08998280.2025.2537558
Ryan S Koch, Kevin T Nguyen, Abhinav A Karnati, Kritin K Verma, Michelle B Tarbox

Rosacea and seborrheic dermatitis are both chronic inflammatory skin conditions with facial distributions. Using the TriNetX database, we investigated the concomitance of rosacea and seborrheic dermatitis. After propensity score matching, rosacea patients had an increased risk of seborrheic dermatitis (odds ratio 6.456; 95% confidence interval, 6.155-6.772; P < 0.0001). This significant correlation emphasizes the importance of clinicians remaining observant for signs of both conditions when diagnosing and managing patients with either disease.

酒渣鼻和脂溢性皮炎都是面部分布的慢性炎症性皮肤病。使用TriNetX数据库,我们调查了酒渣鼻和脂溢性皮炎的并发性。倾向评分匹配后,酒渣鼻患者患脂溢性皮炎的风险增加(优势比6.456;95%可信区间6.155-6.772;P
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引用次数: 0
Efficacy and safety of iron supplements for restless leg syndrome, a systematic review, meta-analysis, meta-regression, and trial sequential analysis of randomized controlled trials. 铁补充剂治疗不宁腿综合征的疗效和安全性:随机对照试验的系统回顾、meta分析、meta回归和试验序贯分析。
Q3 Medicine Pub Date : 2025-07-28 eCollection Date: 2025-01-01 DOI: 10.1080/08998280.2025.2527549
Abdelrahman Mahmoud, Hazem Mohamed Salamah, Hassan Alshaker, Ali Ashraf Salah Ahmed, Mohamed R Abdelraouf, Husam Abu Suilik, Mohamed Abuelazm, Basel Abdelazeem

Background: Restless leg syndrome (RLS) is a common neurological condition that can affect the quality of life. Iron is one of the available options for the treatment of RLS.

Methods: This systematic review and meta-analysis assessed the efficacy and safety of different iron regimens in treating RLS. We searched EMBASE, SCOPUS, Web of Science, PubMed, and Cochrane databases for studies that assessed the effects of different iron supplements compared to placebo on the International RLS score (IRLS), RLS-Quality of Life (QOL) score, sleep visual analog score (VAS), and adverse events (AEs).

Results: Twelve randomized controlled trials with 511 patients were included. Iron improved the IRLS score (mean difference [MD] = -5.28; 95% confidence interval [CI] - 7.66, -2.90; P < 0.0001), the number of patients with improved IRLS score (risk ratio [RR] = 2.06; 95% CI 1.49, 2.84; P < 0.0001), RLS-QOL (MD = 7.42; 95% CI 1.32, 13.51; P = 0.02), and sleep VAS score (MD = -24.83; 95% CI -40.08, -9.58; P = 0.001), but yielded more overall AEs (RR = 2.04; 95% CI 1.46, 2.85; P < 0.0001), with no difference in serious AEs or those leading to drug discontinuation (RR = 2.04; 95% CI 0.39, 10.81; P = 0.40 and RR = 6.25; 95% CI 0.79, 49.54; P = 0.08), respectively.

Conclusion: Iron, especially ferric carboxymaltose, is a valuable option for RLS, which showed improvement in several indices.

背景:不宁腿综合征(RLS)是一种常见的影响生活质量的神经系统疾病。铁是治疗RLS的可用选择之一。方法:本系统综述和荟萃分析评估了不同铁方案治疗RLS的有效性和安全性。我们检索了EMBASE、SCOPUS、Web of Science、PubMed和Cochrane数据库,以评估与安慰剂相比,不同铁补充剂对国际RLS评分(IRLS)、RLS-生活质量评分(QOL)、睡眠视觉模拟评分(VAS)和不良事件(ae)的影响。结果:纳入12项随机对照试验,511例患者。铁改善了IRLS评分(平均差值[MD] = -5.28; 95%可信区间[CI] - 7.66, -2.90; P P P = 0.02)和睡眠VAS评分(MD = -24.83; 95% CI -40.08, -9.58; P = 0.001),但产生了更多的总ae (RR = 2.04; 95% CI 1.46, 2.85; P = 0.40, RR = 6.25; 95% CI 0.79, 49.54; P = 0.08)。结论:铁,尤其是羧基麦芽糖铁,是治疗RLS的有价值的选择,其多项指标均有改善。
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引用次数: 0
Prediction of coronary no-reflow from the surface electrocardiogram. 从体表心电图预测冠状动脉无血流。
Q3 Medicine Pub Date : 2025-07-28 eCollection Date: 2025-01-01 DOI: 10.1080/08998280.2025.2537499
Javier E Banchs
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引用次数: 0
Multivessel coronary artery disease: Teamwork makes the dream work. 多支冠状动脉疾病:团队合作让梦想成真。
Q3 Medicine Pub Date : 2025-07-28 eCollection Date: 2025-01-01 DOI: 10.1080/08998280.2025.2527557
Alexander D Sweeting, Saraschandra Vallabhajosyula
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引用次数: 0
Isolated orbital mucormycosis in the setting of COVID-19 pneumonia. COVID-19肺炎背景下孤立性眼眶毛霉菌病的研究。
Q3 Medicine Pub Date : 2025-07-25 eCollection Date: 2025-01-01 DOI: 10.1080/08998280.2025.2528284
Kimberly K Nguyen, John D Ng

Mucormycosis is a fungal infection most commonly affecting severely ill patients, with increasing incidence in the setting of the COVID-19 pandemic. Due to its ability to involve multiple structures including the paranasal sinuses, orbit, and brain, mucormycosis infections present with variable clinical signs. All previously reported cases of mucormycosis in the literature involved paranasal sinus involvement, most commonly the ethmoid sinus. Herein we present the first reported case of isolated orbital mucormycosis without histologic evidence of paranasal sinus infection. Prompt recognition of atypical mucormycosis infections in the absence of paranasal sinus involvement in critically ill patients is necessary in order to initiate early and aggressive treatment due to the high fatality rate and rarity of this presentation.

毛霉病是一种真菌感染,最常见于重症患者,在2019冠状病毒病大流行背景下发病率不断上升。由于它能累及包括鼻窦、眼眶和脑在内的多个结构,毛霉菌病感染表现出不同的临床症状。所有先前报道的毛霉菌病病例都涉及鼻副窦,最常见的是筛窦。在此,我们报告第一例孤立的眼眶毛霉菌病,没有鼻窦感染的组织学证据。由于这种疾病的高致死率和罕见性,危重患者在没有鼻窦受损伤的情况下,及时识别非典型毛霉菌感染是必要的,以便及早进行积极的治疗。
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引用次数: 0
Treatment charges for acute coronary syndrome: A retrospective analysis. 急性冠脉综合征的治疗费用:回顾性分析。
Q3 Medicine Pub Date : 2025-07-25 eCollection Date: 2025-01-01 DOI: 10.1080/08998280.2025.2530809
Luke Frizzell, Jonathan Deleon, Sean Reilly, Kendal Hammonds, Jose E Exaire, Timothy A Mixon, Billy Don Jones, Christopher Chiles, R Jay Widmer

Background: This study analyzes the costs associated with treatment strategies for acute coronary syndrome: coronary artery bypass grafting (CABG), percutaneous coronary intervention (PCI), and medical management (MM).

Methods: This is a substudy of a previous analysis showing improved outcomes with CABG compared to PCI and MM, now focusing on variation in charges based on the type of treatment, hospital length of stay (LOS), and the occurrence of hospital readmission. We extracted total reimbursements, LOS, and readmissions for acute coronary syndrome patients (4267) between 2018 and 2022 from the electronic health record.

Results: Expenses related to total charges were higher for CABG patients than PCI patients (+$106,047); however, average daily charges were lower for CABG patients compared to PCI patients (+$14,957). LOS was a primary driver for total charges, as CABG patients stayed 8.35 ± 0.50 days longer than PCI patients on average. The average difference between the total charge amount for readmitted and nonreadmitted patients was $22,765 ± $11,820. Even though readmission increases total charges, the charge per day was still less in patients with readmission due to their longer LOS.

Conclusion: The higher total charge amount and lower charge per day in CABG patients compared to PCI patients, as well as readmitted patients, highlights the importance of employing strategies to reduce LOS and minimize charges for CABG and readmissions.

背景:本研究分析了急性冠状动脉综合征治疗策略的相关成本:冠状动脉旁路移植术(CABG)、经皮冠状动脉介入治疗(PCI)和医疗管理(MM)。方法:这是先前分析的一项亚研究,该分析显示与PCI和MM相比,CABG改善了结果,现在关注的是基于治疗类型、住院时间(LOS)和再入院发生率的收费变化。我们从电子健康记录中提取了2018年至2022年期间急性冠状动脉综合征患者(4267人)的总报销、LOS和再入院率。结果:CABG患者总费用相关费用高于PCI患者(+ 106,047美元);然而,与PCI患者相比,CABG患者的平均每日费用较低(+$14,957)。LOS是总费用的主要驱动因素,CABG患者比PCI患者平均停留时间长8.35±0.50天。再入院和非再入院患者的总费用平均差值为22,765±11,820美元。尽管再入院增加了总费用,但由于LOS较长,再入院患者每天的费用仍然较低。结论:与PCI患者和再入院患者相比,CABG患者的总费用较高,每日费用较低,这突出了采用策略降低LOS和最小化CABG和再入院费用的重要性。
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引用次数: 0
Quantifying cardiovascular disease burden attributable to risk factors in Pakistan: a call for data-driven action. 量化巴基斯坦可归因于风险因素的心血管疾病负担:呼吁采取数据驱动的行动。
Q3 Medicine Pub Date : 2025-07-25 eCollection Date: 2025-01-01 DOI: 10.1080/08998280.2025.2531721
Ahmed Kamal Siddiqi, Zainab Samad, Muhammad Shahzeb Khan
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引用次数: 0
From education to patient care: the impact of weight stigma in healthcare. 从教育到病人护理:医疗保健中体重歧视的影响。
Q3 Medicine Pub Date : 2025-07-25 eCollection Date: 2025-01-01 DOI: 10.1080/08998280.2025.2528397
Emma D'Arpino, Suzie Kardong-Edgren

This scoping review explored the literature about weight stigma in healthcare education and patient care and how it may impact individuals living in larger bodies. Two databases, MGH OneSearch and PubMed, were utilized, focusing on research published from 2013 to 2023 in English. A total of 18 articles were identified and used for this review. Evidence indicated that healthcare providers stigmatize patients living in larger bodies, both implicitly and explicitly. Studies found that medical students preferred thin patients and had strong anti-fat bias (P < 0.001). Weight bias in healthcare can lead to discrimination, impacting patients' mental and physical well-being, including heightened stress, altered caloric intake, fluctuations in body size, and declining overall health. The impact of weight stigma in healthcare is recognized but understudied. This review suggests that believing weight is within patient control fosters blame and stigma. Learning about weight stigma and developing nonstigmatizing education for healthcare students and providers should be a priority. Understanding how weight stigma may delay healthcare and increase chronic illness risk could encourage more compassionate care for patients in larger bodies.

本综述探讨了有关医疗保健教育和患者护理中体重耻辱感的文献,以及它如何影响生活在较大身体中的个体。使用MGH OneSearch和PubMed两个数据库,重点关注2013年至2023年发表的英文研究。本综述共纳入18篇文献。有证据表明,医疗保健提供者对生活在较大身体中的患者进行了污名化,无论是隐性的还是显性的。研究发现,医学生更喜欢瘦的病人,有强烈的抗胖偏见(P
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引用次数: 0
Intraoperative cardiac arrest from suspected anaphylaxis to morphine. 术中疑似吗啡过敏引起的心脏骤停。
Q3 Medicine Pub Date : 2025-07-25 eCollection Date: 2025-01-01 DOI: 10.1080/08998280.2025.2531726
Prashant Sirohiya, Surabhi Sandill, Surya Theja, Vasudha Ahuja, Smriti Panda

We report the case of a 62-year-old man who experienced intraoperative anaphylaxis following intravenous morphine administration during head and neck surgery. Immediate resuscitation was successful, and subsequent allergy workup demonstrated a positive skin prick test to morphine. This case underscores the diagnostic complexity of perioperative anaphylaxis and emphasizes the critical role of guideline-directed allergy evaluation in identifying the offending agent and ensuring safe future anesthetic management.

我们报告的情况下,62岁的男子谁经历了术中过敏反应后静脉注射吗啡在头颈部手术。立即复苏成功,随后的过敏检查显示吗啡皮肤点刺试验阳性。该病例强调了围手术期过敏反应诊断的复杂性,并强调了指导过敏反应评估在确定不良药物和确保安全的未来麻醉管理中的关键作用。
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引用次数: 0
期刊
Baylor University Medical Center Proceedings
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