Pub Date : 2018-07-31DOI: 10.2174/1874279301810010101
Alessandro Porta, F. Lizzoli, E. Racchi, C. Scaramuzza, L. Parola
Tuberculosis (TB) is currently a major health problem, in particular in developing countries and in HIV positive people. Tubercular spondylodiscitis is the most common type of skeletal TB, more frequent in children than adults. It is rarely reported in developed countries.We describe a 3 years-old Italian girl who referred to our hospital with back pain and walking deficiency; she had a very good outcome with anti-tubercular treatment and orthopedic follow-up.Early recognition and treatment of this tubercular complication are very important due to its possible complications: bone destruction, spinal deformity, neurologic and orthopedic complications.
{"title":"Pott’s Disease in a 3 Years Old Italian Child: Case Report and Review of the Literature","authors":"Alessandro Porta, F. Lizzoli, E. Racchi, C. Scaramuzza, L. Parola","doi":"10.2174/1874279301810010101","DOIUrl":"https://doi.org/10.2174/1874279301810010101","url":null,"abstract":"Tuberculosis (TB) is currently a major health problem, in particular in developing countries and in HIV positive people. Tubercular spondylodiscitis is the most common type of skeletal TB, more frequent in children than adults. It is rarely reported in developed countries.We describe a 3 years-old Italian girl who referred to our hospital with back pain and walking deficiency; she had a very good outcome with anti-tubercular treatment and orthopedic follow-up.Early recognition and treatment of this tubercular complication are very important due to its possible complications: bone destruction, spinal deformity, neurologic and orthopedic complications.","PeriodicalId":88330,"journal":{"name":"The open infectious diseases journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48940321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-07-19DOI: 10.2174/1874279301810010079
G. Delpech, N. Allende, S. Lissarrague, M. Sparo
Urinary Tract Infection (UTI) is a common cause of morbidity and mortality in older adults.To investigate antimicrobial resistance of uropathogenicEscherichia colifrom elderly patients in a General Hospital, Argentina.During the period July 2011-July 2015, patients over 70 years old with urinary tract infections, without urinary catheters and with no antimicrobial therapy the previous week before sampling, were included. Phenotypic characterization was carried out.In vitroqualitative and quantitative antimicrobial resistances were investigated. Antimicrobials assayed: ampicillin, amoxicillin-clavulanate, cefazolin, cefuroxime, cefoxitin, cefotaxime, ceftazidime, cefepime, imipenem, ertapenem, gentamicin, nalidixic acid, ciprofloxacin, trimethoprim-sulfamethoxazole (TMS) and nitrofurantoin. Patients’ medical records were produced, and risk factors were analyzed by multivariate analysis.768 bacterial isolates were identified asE. coli. Resistances to ampicillin (80.5%), nalidixic acid (61.7%), ciprofloxacin (42.8%), TMS (37.6%), amoxicillin-clavulanate (28.6%), cefazolin (21.6%), cefuroxime (20.7%), gentamicin (13.8%), cefotaxime (9.7%), ceftazidime (9.7%), cefepime (8.4%), cefoxitin (3.1%) and nitrofurantoin (2.3%) were observed. Resistance to carbapenems was not expressed. Production of extended spectrum β-lactamases was detected (7.6%) in community acquired (96%) and healthcare associated (4%) isolates. The independent risk factors for urinary infections produced by multi-resistantE. coliwere: diabetes mellitus, recurrent infections, hospitalization during the last year and exposure to β-lactams in the last 3 months.A high prevalence of resistance to β-lactams and to other antimicrobials was observed. Detection of antimicrobial multi-resistant isolates highlights the need of antimicrobial resistance surveillance in elderly patients with urinary tract infections.
{"title":"Antimicrobial Resistance of Uropathogenic Escherichia coli from Elderly Patients at a General Hospital, Argentina","authors":"G. Delpech, N. Allende, S. Lissarrague, M. Sparo","doi":"10.2174/1874279301810010079","DOIUrl":"https://doi.org/10.2174/1874279301810010079","url":null,"abstract":"Urinary Tract Infection (UTI) is a common cause of morbidity and mortality in older adults.To investigate antimicrobial resistance of uropathogenicEscherichia colifrom elderly patients in a General Hospital, Argentina.During the period July 2011-July 2015, patients over 70 years old with urinary tract infections, without urinary catheters and with no antimicrobial therapy the previous week before sampling, were included. Phenotypic characterization was carried out.In vitroqualitative and quantitative antimicrobial resistances were investigated. Antimicrobials assayed: ampicillin, amoxicillin-clavulanate, cefazolin, cefuroxime, cefoxitin, cefotaxime, ceftazidime, cefepime, imipenem, ertapenem, gentamicin, nalidixic acid, ciprofloxacin, trimethoprim-sulfamethoxazole (TMS) and nitrofurantoin. Patients’ medical records were produced, and risk factors were analyzed by multivariate analysis.768 bacterial isolates were identified asE. coli. Resistances to ampicillin (80.5%), nalidixic acid (61.7%), ciprofloxacin (42.8%), TMS (37.6%), amoxicillin-clavulanate (28.6%), cefazolin (21.6%), cefuroxime (20.7%), gentamicin (13.8%), cefotaxime (9.7%), ceftazidime (9.7%), cefepime (8.4%), cefoxitin (3.1%) and nitrofurantoin (2.3%) were observed. Resistance to carbapenems was not expressed. Production of extended spectrum β-lactamases was detected (7.6%) in community acquired (96%) and healthcare associated (4%) isolates. The independent risk factors for urinary infections produced by multi-resistantE. coliwere: diabetes mellitus, recurrent infections, hospitalization during the last year and exposure to β-lactams in the last 3 months.A high prevalence of resistance to β-lactams and to other antimicrobials was observed. Detection of antimicrobial multi-resistant isolates highlights the need of antimicrobial resistance surveillance in elderly patients with urinary tract infections.","PeriodicalId":88330,"journal":{"name":"The open infectious diseases journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43433667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-29DOI: 10.2174/1874279301810010063
I. Tolmane, B. Rozentāle, S. Arutjunana, A. Jēruma, V. Ķūse, Raimonds Simanis
Despite effective treatment available from 2016 in Latvia, there are restrictions - only patients with fibrosis (F, Metavir) stage 3 to 4 have access to reimbursed medicines. Some patients obtain generic drugs from India. The aim of this study was to evaluate the efficacy of original and generic direct acting antiviral medications in Latvian patients. This is a retrospective study of 179 chronic virologic hepatitis C patients. Data were obtained from patients’ medical records. Mean age 49.2 years (SD 10.2, range 24-71), 88 female patients (49%), 91 male patients (51%). Genotype 1b was detected in 157 patients (87.7%). Patients were divided into two groups - patients who received original direct acting antivirals ombitasvir, paritaprevir, ritonavir, dasabuvir + ribavirin (n=144, F3-4, Child-Pugh A) and those who received generic medicines from India (n=35, F0-2) sofosbuvir, ledipasvir (n=7) or sofosbuvir, daclatasvir + ribavirin (n=28). Undetectable viral load 12 weeks after cessation of therapy (sustained virologic response 12 or SVR12) was measured in all patients. Therapy course completed 142 patients from original medicines group and all patients from generics group. In the original medicines group - sustained viralogic response was achieved in 142 patients who completed treatment course (100%), while in generic medicines group in 32 patients (91.4%). Study results show high efficacy of both regimens using original and generic medicines - sustained virologic response was achieved in more than 90% of patients, with slight superiority in original medicines group.
{"title":"Original Versus Generic Direct Acting Antivirals in Treatment of Chronic Hepatitis C Patients: Real Life Data From Latvia","authors":"I. Tolmane, B. Rozentāle, S. Arutjunana, A. Jēruma, V. Ķūse, Raimonds Simanis","doi":"10.2174/1874279301810010063","DOIUrl":"https://doi.org/10.2174/1874279301810010063","url":null,"abstract":"\u0000 \u0000 Despite effective treatment available from 2016 in Latvia, there are restrictions - only patients with fibrosis (F, Metavir) stage 3 to 4 have access to reimbursed medicines. Some patients obtain generic drugs from India.\u0000 \u0000 \u0000 \u0000 The aim of this study was to evaluate the efficacy of original and generic direct acting antiviral medications in Latvian patients.\u0000 \u0000 \u0000 \u0000 This is a retrospective study of 179 chronic virologic hepatitis C patients. Data were obtained from patients’ medical records. Mean age 49.2 years (SD 10.2, range 24-71), 88 female patients (49%), 91 male patients (51%). Genotype 1b was detected in 157 patients (87.7%). Patients were divided into two groups - patients who received original direct acting antivirals ombitasvir, paritaprevir, ritonavir, dasabuvir + ribavirin (n=144, F3-4, Child-Pugh A) and those who received generic medicines from India (n=35, F0-2) sofosbuvir, ledipasvir (n=7) or sofosbuvir, daclatasvir + ribavirin (n=28). Undetectable viral load 12 weeks after cessation of therapy (sustained virologic response 12 or SVR12) was measured in all patients. Therapy course completed 142 patients from original medicines group and all patients from generics group.\u0000 \u0000 \u0000 \u0000 In the original medicines group - sustained viralogic response was achieved in 142 patients who completed treatment course (100%), while in generic medicines group in 32 patients (91.4%).\u0000 \u0000 \u0000 \u0000 Study results show high efficacy of both regimens using original and generic medicines - sustained virologic response was achieved in more than 90% of patients, with slight superiority in original medicines group.\u0000","PeriodicalId":88330,"journal":{"name":"The open infectious diseases journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42695579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-29DOI: 10.2174/1874279301810010047
J. Rajčáni, S. Szathmary
{"title":"Peptide Vaccines: New Trends for Avoiding the Autoimmune Response","authors":"J. Rajčáni, S. Szathmary","doi":"10.2174/1874279301810010047","DOIUrl":"https://doi.org/10.2174/1874279301810010047","url":null,"abstract":"","PeriodicalId":88330,"journal":{"name":"The open infectious diseases journal","volume":"10 1","pages":"47-62"},"PeriodicalIF":0.0,"publicationDate":"2018-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46546168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-29DOI: 10.2174/1874279301810010071
Christopher J. Parronchi, V. Doshi, R. Nahass
Histoplasma Capsulatum (HC) is one of the most common endemic mycoses in the United States of America, and has also been reported in large numbers in various regions of Central and South America. It can cause disease ranging in severity from an upper respiratory tract-like infection, to deep single organ disease and most concerning, widely disseminated disease resulting in harmful sequelae. Presumed Ocular Histoplasmosis Syndrome (POHS) is the most common ocular manifestation of histoplasmosis and usually results in permanent disability. In this study, we describe a rarely reported case of histoplasmosis endophthalmitis that was treated with itraconazole and resulted in almost complete resolution of all retinal findings and symptoms.
{"title":"Histoplasmosis Endophthalmitis – Case Report and Review","authors":"Christopher J. Parronchi, V. Doshi, R. Nahass","doi":"10.2174/1874279301810010071","DOIUrl":"https://doi.org/10.2174/1874279301810010071","url":null,"abstract":"\u0000 \u0000 Histoplasma Capsulatum (HC) is one of the most common endemic mycoses in the United States of America, and has also been reported in large numbers in various regions of Central and South America. It can cause disease ranging in severity from an upper respiratory tract-like infection, to deep single organ disease and most concerning, widely disseminated disease resulting in harmful sequelae. Presumed Ocular Histoplasmosis Syndrome (POHS) is the most common ocular manifestation of histoplasmosis and usually results in permanent disability. \u0000 \u0000 \u0000 \u0000 In this study, we describe a rarely reported case of histoplasmosis endophthalmitis that was treated with itraconazole and resulted in almost complete resolution of all retinal findings and symptoms.\u0000","PeriodicalId":88330,"journal":{"name":"The open infectious diseases journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48808232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-26DOI: 10.2174/1874279301810010043
A. Fouad, F. Bennaoui, N. Slitine, N. Soraa, F. Maoulainine
Imipenem-resistant Acinetobacter baumannii meningitis is a hospital-acquired infection, the treatment of which constitutes a real therapeutic challenge. In this article, together with a review of the literature, we report two cases of imipenem-resistant Acinetobacter baumannii neonatal meningitis following ruptured myelomeningocele, treated with intravenous colistin with favorable results. In recent years, Acinetobacter baumannii has become a more and more commonly described pathogen in hospital-acquired infections. However, the cases of meningitis are mainly postoperative and are still not quite frequently described in the literature. Colistin appears to be preferably administered intravenously at a dose of 100.000 IU/kg/day.
{"title":"Nosocomial Neonatal Meningitis with Acinetobacter Baumannii on Myelomeningocele: A Real Therapeutic Challenge","authors":"A. Fouad, F. Bennaoui, N. Slitine, N. Soraa, F. Maoulainine","doi":"10.2174/1874279301810010043","DOIUrl":"https://doi.org/10.2174/1874279301810010043","url":null,"abstract":"Imipenem-resistant Acinetobacter baumannii meningitis is a hospital-acquired infection, the treatment of which constitutes a real therapeutic challenge. In this article, together with a review of the literature, we report two cases of imipenem-resistant Acinetobacter baumannii neonatal meningitis following ruptured myelomeningocele, treated with intravenous colistin with favorable results. In recent years, Acinetobacter baumannii has become a more and more commonly described pathogen in hospital-acquired infections. However, the cases of meningitis are mainly postoperative and are still not quite frequently described in the literature. Colistin appears to be preferably administered intravenously at a dose of 100.000 IU/kg/day.","PeriodicalId":88330,"journal":{"name":"The open infectious diseases journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46578639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-18DOI: 10.2174/1874279301810010076
A. Fouad, F. Bennaoui, N. Slitine, N. Soraa, F. Maoulainine
Harlequin ichthyosis is a rare and fatal fetal disorder, most often complicated by infection. Sepsis due to Vibrio cholerae is rare, especially in neonatology. The association between ichthyosis and Vibrio cholerae infection has never been described in medical literature. We report the case of a newborn admitted to the neonatal intensive care unit, with a typical characteristics of Harlequin ichthyosis and a sepsis due to Vibrio cholerae, diagnosed with the blood culture. The outcome was fatal; characterized by death six hours after his hospitalization. Cases of Harlequin ichthyosis complicated with septicemia with Pseudomonas Aeruginosa have been described. Vibrio cholerae infections are usually confined to the gastrointestinal tract but some species, especially non-01 strains, can cause extra-intestinal infections including septicemia and meningitis.
{"title":"Vibrio Cholerae Septicemia and Harlequin Ichthyosis: Outstanding Association","authors":"A. Fouad, F. Bennaoui, N. Slitine, N. Soraa, F. Maoulainine","doi":"10.2174/1874279301810010076","DOIUrl":"https://doi.org/10.2174/1874279301810010076","url":null,"abstract":"\u0000 \u0000 Harlequin ichthyosis is a rare and fatal fetal disorder, most often complicated by infection. Sepsis due to Vibrio cholerae is rare, especially in neonatology. The association between ichthyosis and Vibrio cholerae infection has never been described in medical literature.\u0000 \u0000 \u0000 \u0000 We report the case of a newborn admitted to the neonatal intensive care unit, with a typical characteristics of Harlequin ichthyosis and a sepsis due to Vibrio cholerae, diagnosed with the blood culture. The outcome was fatal; characterized by death six hours after his hospitalization.\u0000 \u0000 \u0000 \u0000 Cases of Harlequin ichthyosis complicated with septicemia with Pseudomonas Aeruginosa have been described. Vibrio cholerae infections are usually confined to the gastrointestinal tract but some species, especially non-01 strains, can cause extra-intestinal infections including septicemia and meningitis.\u0000","PeriodicalId":88330,"journal":{"name":"The open infectious diseases journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43994708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-05-14DOI: 10.2174/1874279301810010029
M. Kawado, S. Hashimoto, Akiko Ohta, M. Oba, K. Taniguchi, T. Sunagawa, T. Matsui, M. Nagai, Y. Murakami
RESEARCH ARTICLE Improvement of Influenza Incidence Estimation Using Auxiliary Information in Sentinel Surveillance in Japan Miyuki Kawado, Shuji Hashimoto, Akiko Ohta, Mari S. Oba, Kiyosu Taniguchi, Tomimasa Sunagawa, Tamano Matsui, Masaki Nagai and Yoshitaka Murakami Department of Hygiene, Fujita Health University School of Medicine, Aichi, Japan Division of Public Health, Department of Social Medicine, Saitama Medical University Faculty of Medicine, Saitama, Japan Department of Medical Statistics, Toho University, Tokyo, Japan Department of Clinical Research, National Mie Hospital, Mie, Japan Infectious Disease Surveillance Center, National Institute of Infectious Diseases, Tokyo, Japan Department of Social Medicine, Saitama Medical University, Saitama, Japan
Miyuki Kawado, Shuji Hashimoto, Akiko Ohta, Mari S. Oba, Kiyosu Taniguchi, Tomimasa Sunagawa, Tamano Matsui, Masaki Nagai和Yoshitaka Murakami卫生系，藤田保健大学医学院，爱知县，日本，埼玉医科大学，公共卫生系，社会医学系，埼玉，日本东宝大学日本医学统计学系，东京，日本国立传染病研究所国立三重医院临床研究部，三重，日本传染病监测中心，东京，日本埼玉医科大学社会医学部，埼玉，日本
{"title":"Improvement of Influenza Incidence Estimation Using Auxiliary Information in Sentinel Surveillance in Japan","authors":"M. Kawado, S. Hashimoto, Akiko Ohta, M. Oba, K. Taniguchi, T. Sunagawa, T. Matsui, M. Nagai, Y. Murakami","doi":"10.2174/1874279301810010029","DOIUrl":"https://doi.org/10.2174/1874279301810010029","url":null,"abstract":"RESEARCH ARTICLE Improvement of Influenza Incidence Estimation Using Auxiliary Information in Sentinel Surveillance in Japan Miyuki Kawado, Shuji Hashimoto, Akiko Ohta, Mari S. Oba, Kiyosu Taniguchi, Tomimasa Sunagawa, Tamano Matsui, Masaki Nagai and Yoshitaka Murakami Department of Hygiene, Fujita Health University School of Medicine, Aichi, Japan Division of Public Health, Department of Social Medicine, Saitama Medical University Faculty of Medicine, Saitama, Japan Department of Medical Statistics, Toho University, Tokyo, Japan Department of Clinical Research, National Mie Hospital, Mie, Japan Infectious Disease Surveillance Center, National Institute of Infectious Diseases, Tokyo, Japan Department of Social Medicine, Saitama Medical University, Saitama, Japan","PeriodicalId":88330,"journal":{"name":"The open infectious diseases journal","volume":"10 1","pages":"29-36"},"PeriodicalIF":0.0,"publicationDate":"2018-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47579755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-04-30DOI: 10.2174/1874279301810010015
A. Comyn, A. Ronayne, M. Nielsen, J. Cleary, R. Cunney, R. Drew
RESEARCH ARTICLE BioFire Film Array Blood Culture Identification Panel for Rapid Detection of Pathogens from Sterile Sites A Diagnostic Accuracy Study Ailbhe Comyn, Aoife Ronayne, Maryke J. Nielsen, Jennifer Cleary, Robert Cunney and Richard J. Drew Department of Microbiology, Temple Street Children’s University Hospital, Dublin 7, Ireland Irish Meningitis and Sepsis Reference Laboratory, Temple Street Children’s University Hospital, Dublin 7, Ireland Clinical Innovation Unit, Rotunda Hospital, Dublin 1, Ireland Department of Clinical Microbiology, Royal College of Surgeons in Ireland, Dublin 2, Ireland
Ailbhe Comyn, Aoife Ronayne, Maryke J. Nielsen, Jennifer Cleary, Robert Cunney和Richard J. Drew爱尔兰都柏林坦普尔街儿童大学医院微生物学系爱尔兰脑膜炎和败血症参考实验室，都柏林7坦普尔街儿童大学医院，爱尔兰临床创新单位，Rotunda医院，爱尔兰皇家外科医学院临床微生物学系，都柏林2，爱尔兰
{"title":"BioFire Film Array Blood Culture Identification Panel for Rapid Detection of Pathogens from Sterile Sites - A Diagnostic Accuracy Study","authors":"A. Comyn, A. Ronayne, M. Nielsen, J. Cleary, R. Cunney, R. Drew","doi":"10.2174/1874279301810010015","DOIUrl":"https://doi.org/10.2174/1874279301810010015","url":null,"abstract":"RESEARCH ARTICLE BioFire Film Array Blood Culture Identification Panel for Rapid Detection of Pathogens from Sterile Sites A Diagnostic Accuracy Study Ailbhe Comyn, Aoife Ronayne, Maryke J. Nielsen, Jennifer Cleary, Robert Cunney and Richard J. Drew Department of Microbiology, Temple Street Children’s University Hospital, Dublin 7, Ireland Irish Meningitis and Sepsis Reference Laboratory, Temple Street Children’s University Hospital, Dublin 7, Ireland Clinical Innovation Unit, Rotunda Hospital, Dublin 1, Ireland Department of Clinical Microbiology, Royal College of Surgeons in Ireland, Dublin 2, Ireland","PeriodicalId":88330,"journal":{"name":"The open infectious diseases journal","volume":"10 1","pages":"15-22"},"PeriodicalIF":0.0,"publicationDate":"2018-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48638171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-04-30DOI: 10.2174/1874279301810010023
F. Mansour-Ghanaei, F. Joukar, A. Samadi, Sara Mavaddati, Arash Daryakar
A 65-year-old man presented with severe pain in central abdomen and periumbilical regions. He had no history of alcohol consumption, smoking and surgery but the history of RA (Rheumatoid Arthritis) and hypothyroidism taking immunosuppressive medications. The patient underwent endoscopy and colonoscopy which pathological analysis of the biopsies revealed remarkable findings in favor of Strongyloidiasis. After two consecutive day’s consumption of ivermectin 200μg/kg, the symptoms were completely removed. Also, the stool examination was negative for S. stercoralis larvae two weeks after end of the treatment.
{"title":"Strongyloides Infection in a Man with Abdominal Pain and a History of Rheumatoid Arthritis","authors":"F. Mansour-Ghanaei, F. Joukar, A. Samadi, Sara Mavaddati, Arash Daryakar","doi":"10.2174/1874279301810010023","DOIUrl":"https://doi.org/10.2174/1874279301810010023","url":null,"abstract":"A 65-year-old man presented with severe pain in central abdomen and periumbilical regions. He had no history of alcohol consumption, smoking and surgery but the history of RA (Rheumatoid Arthritis) and hypothyroidism taking immunosuppressive medications. The patient underwent endoscopy and colonoscopy which pathological analysis of the biopsies revealed remarkable findings in favor of Strongyloidiasis. After two consecutive day’s consumption of ivermectin 200μg/kg, the symptoms were completely removed. Also, the stool examination was negative for S. stercoralis larvae two weeks after end of the treatment.","PeriodicalId":88330,"journal":{"name":"The open infectious diseases journal","volume":"10 1","pages":"23-28"},"PeriodicalIF":0.0,"publicationDate":"2018-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42760835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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