Background: Nonalcoholic fatty liver disease (NAFLD) is a common liver disease associated with inactivity and obesity. Physical activity and exercise could affect the risk of NAFLD progression by improving the hepatic lipid profiles. Objectives: The current study aimed to evaluate the efficacy of combination of aerobic and resistance training on hepatic enzymes in males with NAFLD. Patients and Methods: The study was a randomized controlled trial. Thirty-two untrained males with NAFLD (aged = 32.93±2.15years, weight = 86.01.51±8.40 kg) were recruited and randomly divided into equal experimental and control groups. The trained group took part in a combination aerobic and resistance training program for eight weeks (three times per week). The control group continued their routine life. The weight, body mass index (BMI) and serum levels of total cholesterol (TC), triglycerides (TG), low density lipoprotein (LDL), high density lipoprotein (HDL), very low density lipoprotein (VLDL), HDL/LDL, TC/HDL, aspartate aminotransferase (AST) and alanine transaminase (ALT) were measured before and after the protocol. Results: Statistical analysis demonstrated that the traininggrouphadsignificant changes in weight, BMI, TC, TG, LDL, VLDL, HDL/LDL, TC/ HDL, AST and ALT, whereas there was no significant change in HDL in NAFLD patients (P < 0.05). Conclusions: The results suggest that physical activity improves metabolic parameters,which interfere in the development of fatty liver and has a protective role against the development of NAFLD. Keywords: Fatty Liver, Exercise, Lipid Profiles, Hepatic Enzymes
{"title":"The Effect of Combined Aerobic and Resistance Training on Hepatic Enzymes in Males With Nonalcoholic Fatty Liver","authors":"M. Hatami, Elham Eftekhari","doi":"10.17795/BHS-36162","DOIUrl":"https://doi.org/10.17795/BHS-36162","url":null,"abstract":"Background: Nonalcoholic fatty liver disease (NAFLD) is a common liver disease associated with inactivity and obesity. Physical activity and exercise could affect the risk of NAFLD progression by improving the hepatic lipid profiles. \u0000Objectives: The current study aimed to evaluate the efficacy of combination of aerobic and resistance training on hepatic enzymes in males with NAFLD. \u0000Patients and Methods: The study was a randomized controlled trial. Thirty-two untrained males with NAFLD (aged = 32.93±2.15years, weight = 86.01.51±8.40 kg) were recruited and randomly divided into equal experimental and control groups. The trained group took part in a combination aerobic and resistance training program for eight weeks (three times per week). The control group \u0000continued their routine life. The weight, body mass index (BMI) and serum levels of total cholesterol (TC), triglycerides (TG), low density lipoprotein (LDL), high density lipoprotein (HDL), very low density lipoprotein (VLDL), HDL/LDL, TC/HDL, aspartate aminotransferase \u0000(AST) and alanine transaminase (ALT) were measured before and after the protocol. \u0000Results: Statistical analysis demonstrated that the traininggrouphadsignificant changes in weight, BMI, TC, TG, LDL, VLDL, HDL/LDL, TC/ HDL, AST and ALT, whereas there was no significant change in HDL in NAFLD patients (P < 0.05). \u0000Conclusions: The results suggest that physical activity improves metabolic parameters,which interfere in the development of fatty liver and has a protective role against the development of NAFLD. \u0000Keywords: Fatty Liver, Exercise, Lipid Profiles, Hepatic Enzymes","PeriodicalId":8849,"journal":{"name":"Biotechnology and Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73731343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Hosseinzadeh, H. Hamadzadeh, Tahmineh Atashgaran, N. Montazeri
Background: In Iran, rhinoplasty has seemingly become the most favorite cosmetic surgery in the recent years, yet, there are limited reports about its psychosocial aspects Objectives: The main goal of this study was to assess self-confidence, body image and social pressure in cosmetic rhinoplasty surgery candidates. Patients and Methods: Using convenience sampling, 210 participants over the age of 20 years were enrolled in this study. The only inclusion criterion was agreement to participate in the study. A standard Likert-type questionnaire was used for gathering related data. This study was ap:proved by the Qazvin University of Medical Sciences. All gathered data were analyzed using the SPSS software with 95% Confidence Interval (CI). Results: Mean and standard deviation of self confidence, body image and social pressure were lower than the normal community. Statistical analyses showed a significant difference between genders only for mean self-confidence (p≤0.05). Conclusions: Cosmetic rhinoplasty candidates are in lower psychosocial status than the normal population. Researchers proposed a randomized clinical trial with at least a 12-month follow-up, to assess the effects of surgery on psychosocial dimensions of clients. Keywords: Self-Confidence, Body Image, Social Pressure, Rhinoplasty
{"title":"Self Confidence, Body Image and Social Pressure in Cosmetic Rhinoplasty Surgery Candidates","authors":"K. Hosseinzadeh, H. Hamadzadeh, Tahmineh Atashgaran, N. Montazeri","doi":"10.17795/BHS-35481","DOIUrl":"https://doi.org/10.17795/BHS-35481","url":null,"abstract":"Background: In Iran, rhinoplasty has seemingly become the most favorite cosmetic surgery in the recent years, yet, there are limited reports about its psychosocial aspects \u0000Objectives: The main goal of this study was to assess self-confidence, body image and social pressure in cosmetic rhinoplasty surgery candidates. \u0000Patients and Methods: Using convenience sampling, 210 participants over the age of 20 years were enrolled in this study. The only inclusion criterion was agreement to participate in the study. A standard Likert-type questionnaire was used for gathering related data. This study was ap:proved by the Qazvin University of Medical Sciences. All gathered data were analyzed using the SPSS \u0000software with 95% Confidence Interval (CI). \u0000Results: Mean and standard deviation of self confidence, body image and social pressure were lower than the normal community. Statistical analyses showed a significant difference between genders only for mean self-confidence (p≤0.05). \u0000Conclusions: Cosmetic rhinoplasty candidates are in lower psychosocial status than the normal population. Researchers proposed a randomized clinical trial with at least a 12-month follow-up, to assess the effects of surgery on psychosocial dimensions of clients. \u0000Keywords: Self-Confidence, Body Image, Social Pressure, Rhinoplasty","PeriodicalId":8849,"journal":{"name":"Biotechnology and Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77059960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Context: The current study aimed to review research articles concerning kinesin-1 traffic control in the neuronal highways Evidence Acquisition: This review article compromised previous studies published since 1980 using PubMed, Google scholar, Embase, Medline, science direct and SID databases according to the keywords. Results: Kinesin-1 often recognizes scaffold proteins or adaptor proteins and binds to cargo membrane proteins directly as part of a protein complex. Several kinases and microtubule associated proteins are identified in the regulation of motor-cargo unloading. The mechanisms by which kinesin-1 recognizes and binds to specific cargos, and how to unload cargo and determine the direction of transport, are now identified. Conclusions: In summary, the current review article demonstrated that some proteins such as adaptors, Scaffolds, chaperons and microtubule associated proteins and some metabolites, hormones, protein kinases and exercise training can regulate kinesin-1 traffic control in neuronal highway. These findings open exciting new areas of kinesin-1 research. Keywords: Kinesin-1, Scaffold Proteins, Adaptor Proteins, Neuronal Transport
{"title":"Kinesin-1 Traffic Control in Neuronal Highway","authors":"M. Rahmati","doi":"10.17795/BHS-35914","DOIUrl":"https://doi.org/10.17795/BHS-35914","url":null,"abstract":"Context: The current study aimed to review research articles concerning kinesin-1 traffic control in the neuronal highways \u0000Evidence Acquisition: This review article compromised previous studies published since 1980 using PubMed, Google scholar, Embase, Medline, science direct and SID databases according to the keywords. \u0000Results: Kinesin-1 often recognizes scaffold proteins or adaptor proteins and binds to cargo membrane proteins directly as part of a protein complex. Several kinases and microtubule associated proteins are identified in the regulation of motor-cargo unloading. The mechanisms by which kinesin-1 recognizes and binds to specific cargos, and how to unload cargo and determine the direction \u0000of transport, are now identified. \u0000Conclusions: In summary, the current review article demonstrated that some proteins such as adaptors, Scaffolds, chaperons and microtubule associated proteins and some metabolites, hormones, protein kinases and exercise training can regulate kinesin-1 traffic \u0000control in neuronal highway. These findings open exciting new areas of kinesin-1 research. \u0000Keywords: Kinesin-1, Scaffold Proteins, Adaptor Proteins, Neuronal Transport","PeriodicalId":8849,"journal":{"name":"Biotechnology and Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73711703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Nouraei, Farangis Sharifi, E. Shahverdi, Mohammad Amin Konjedi
Background: Vaginitis is the most commongynecological problem and the second mostcommon infection. This condition occurs in approximately 90% of the affected females; secondary to bacterial vaginosis and vulvovaginal candidiasis. Objectives: According to the high prevalence of vulvovaginal candidiasis in Iran and because of the importance of controlling causing species, the current study aimed to evaluate the prevalence of symptomatic vaginal candidiasis among females referred to the hospitals affiliated to Shahid Beheshti University in Tehran, Iran in 2014. Patients and Methods: In this cross-sectional study, 580 females suspected of vulvovaginal candidiasis were selected by simple random sampling. In lithotomy position and after using sterile speculum without lubrication a fluid sample was obtained from the upper part of the lateral wall of the vagina and the samples were cultured on agar medium. All samples were examined by the same gynecologist. Results: The prevalence of vaginal candidiasis was 15.5% and Candida albicans was observed in 92.3% of the subjects. Conclusions: Candida albicans was the most common cause of vaginal candidiasis. Keywords: Prevalence, Vaginal Candidiasis, Candida albicans
{"title":"The Prevalence of Symptomatic Vaginal Candidiasis Among Females in Tehran, 2014","authors":"S. Nouraei, Farangis Sharifi, E. Shahverdi, Mohammad Amin Konjedi","doi":"10.17795/BHS-34642","DOIUrl":"https://doi.org/10.17795/BHS-34642","url":null,"abstract":"Background: Vaginitis is the most commongynecological problem and the second mostcommon infection. This condition occurs in approximately 90% of the affected females; secondary to bacterial vaginosis and vulvovaginal candidiasis. \u0000Objectives: According to the high prevalence of vulvovaginal candidiasis in Iran and because of the importance of controlling causing species, the current study aimed to evaluate the prevalence of symptomatic vaginal candidiasis among females referred to the hospitals affiliated to Shahid Beheshti University in Tehran, Iran in 2014. \u0000Patients and Methods: In this cross-sectional study, 580 females suspected of vulvovaginal candidiasis were selected by simple random sampling. In lithotomy position and after using sterile speculum without lubrication a fluid sample was obtained from the upper part of the lateral wall of the vagina and the samples were cultured on agar medium. All samples were examined by the same gynecologist. \u0000Results: The prevalence of vaginal candidiasis was 15.5% and Candida albicans was observed in 92.3% of the subjects. \u0000Conclusions: Candida albicans was the most common cause of vaginal candidiasis. \u0000Keywords: Prevalence, Vaginal Candidiasis, Candida albicans","PeriodicalId":8849,"journal":{"name":"Biotechnology and Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75675357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Faghihi, M. Paknejad, M. Sarookhani, S. Soukhtehzari, H. Zare, Hosein Gahremani, M. Rasaee
Background: Bladder cancer is a major worldwide health problem. Diagnosis of acute and chronic bladder carcinoma is based on the detection of a number of tumor markers such as nmp22 (nuclear matrix protein 22). Nmp22 is one of the tumor markers used for detecting the recurrence of bladder cancer. Objectives: The aim of this study was to develop hybrid cell producing monoclonal antibodies (MAbs), specifically for nmp22 using hybridoma technology. Materials and Methods: Complete and incomplete adjuvant with recombinant truncated nmp22 antigens were emulsified and injected to BALB/c mice. The spleen was removed and the splenocytes were fused with sp2/0 myeloma cells. Characterization of the produced mAb was carried out. Results: As a result of the fusion, hybridoma cells were produced and exhibited high- titer antibodies. By testing of colons based on the EnzymeLinkedImmunosorbent Assay (ELISA), 135hybridomacolonswere selected, out of whicheight high titer clones including 54D-6F-2E-36-7H-2A-8E-1D-6D were detected and one of the clones named FPR92 was selected, and the produced mAb was further characterized. The produced antibody belongs to the IgG class and its light chain was kappa. With respect to affinity, the mAb was included as high affinity 3�10-7 reacting with NMP22 recombinant protein .The western blot of cancerous bladder tissue showed the presence of 40 and 55 kD proteins as major bands that reacted with this mAb. Conclusions: Based on a double limiting dilution protocol, a type of monoclonal antibody, named FPR92 was produced and characterized. Keywords: Nmp22, Hybridoma, mAb, FPR92, Characterization
{"title":"Preparation and Characterization of Monoclonal Antibody Against Truncated Recombinant Nuclear Matrix Protein (NMP22)","authors":"M. Faghihi, M. Paknejad, M. Sarookhani, S. Soukhtehzari, H. Zare, Hosein Gahremani, M. Rasaee","doi":"10.17795/BHS-34332","DOIUrl":"https://doi.org/10.17795/BHS-34332","url":null,"abstract":"Background: Bladder cancer is a major worldwide health problem. Diagnosis of acute and chronic bladder carcinoma is based on \u0000the detection of a number of tumor markers such as nmp22 (nuclear matrix protein 22). Nmp22 is one of the tumor markers used \u0000for detecting the recurrence of bladder cancer. \u0000Objectives: The aim of this study was to develop hybrid cell producing monoclonal antibodies (MAbs), specifically for nmp22 using \u0000hybridoma technology. \u0000Materials and Methods: Complete and incomplete adjuvant with recombinant truncated nmp22 antigens were emulsified and \u0000injected to BALB/c mice. The spleen was removed and the splenocytes were fused with sp2/0 myeloma cells. Characterization of the \u0000produced mAb was carried out. \u0000Results: As a result of the fusion, hybridoma cells were produced and exhibited high- titer antibodies. By testing of colons based on \u0000the EnzymeLinkedImmunosorbent Assay (ELISA), 135hybridomacolonswere selected, out of whicheight high titer clones including \u000054D-6F-2E-36-7H-2A-8E-1D-6D were detected and one of the clones named FPR92 was selected, and the produced mAb was further \u0000characterized. The produced antibody belongs to the IgG class and its light chain was kappa. With respect to affinity, the mAb was \u0000included as high affinity 3�10-7 reacting with NMP22 recombinant protein .The western blot of cancerous bladder tissue showed \u0000the presence of 40 and 55 kD proteins as major bands that reacted with this mAb. \u0000Conclusions: Based on a double limiting dilution protocol, a type of monoclonal antibody, named FPR92 was produced and characterized. \u0000Keywords: Nmp22, Hybridoma, mAb, FPR92, Characterization","PeriodicalId":8849,"journal":{"name":"Biotechnology and Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86561678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mojtaba Shahmohammadi, M. Javadi, Marjan Nassiri-Asl
Context: Food spoilage has been acommonproblem throughout history, andmuchof the spoilage is caused the activity of microorganisms or enzymatic reactions during the storage of food. Thus, using chemical substances could prevent or delay food spoilage and this has led to the great success of these compounds in the treatment of human diseases. Sodium benzoate is one of the synthetic additives that are widely used in the food industry. Evidence Acquisition: In this review we summarized the history and role of benzoate sodium in the food industry, its limited value in different food, other uses, pharmacokinetics, and its toxicity in animal studies. A literature search was carried out using MEDLINE, Scopus, Science Direct, and Scientific Information Databases (SID). Results: Sodium benzoate is used in different industries as well as the food industry and it has adverse effects similar to other food additives. Conclusions: Studies on natural ingredients in foods to find compounds with similar effects as benzoate with less adverse effects is necessary. Keywords: Sodium Benzoate, Preservative, Food Safety, Spoilage
{"title":"An Overview on the Effects of Sodium Benzoate as a Preservative in Food Products","authors":"Mojtaba Shahmohammadi, M. Javadi, Marjan Nassiri-Asl","doi":"10.17795/BHS-35084","DOIUrl":"https://doi.org/10.17795/BHS-35084","url":null,"abstract":"Context: Food spoilage has been acommonproblem throughout history, andmuchof the spoilage is caused the activity of microorganisms or enzymatic reactions during the storage of food. Thus, using chemical substances could prevent or delay food spoilage and this has led to the great success of these compounds in the treatment of human diseases. Sodium benzoate is one of the synthetic additives that are widely used in the food industry. \u0000Evidence Acquisition: In this review we summarized the history and role of benzoate sodium in the food industry, its limited value in different food, other uses, pharmacokinetics, and its toxicity in animal studies. A literature search was carried out using MEDLINE, \u0000Scopus, Science Direct, and Scientific Information Databases (SID). \u0000Results: Sodium benzoate is used in different industries as well as the food industry and it has adverse effects similar to other food additives. \u0000Conclusions: Studies on natural ingredients in foods to find compounds with similar effects as benzoate with less adverse effects is necessary. \u0000Keywords: Sodium Benzoate, Preservative, Food Safety, Spoilage","PeriodicalId":8849,"journal":{"name":"Biotechnology and Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82095333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Mogadam, M. Samadzadeh, B. Shahbazzadegan, Bita Movaffag
Background: Schizophrenia is a psychiatric disorder characterized by chronic disturbances of thought and perception. Objectives: The current study aimed to compare perceived stress in females with schizophrenia and that of healthy people. Patients and Methods: The study sample included 50 patients with schizophrenia in Tuba rehabilitation center in Ardabil selected by available sampling method. Healthy group participants were selected through cloning by age, gender and marital status of the patient group. The data were collected by the questionnaire of Holmes-Rahe scale and Cohen et al. Data were analyzed by multivariate ANOVA (MANOVA) using SPSS software. Results: Compared with the normal subjects, patients with schizophrenia had a higher mean score in negative perceived and experienced stresses, but had a lower mean score in positive perceived stress as well as in total perceived stress. Conclusions: Results showed the levels of perceived stress and negative stress play important role in the creation and maintenance of schizophrenia. Keywords: Schizophrenia, Stress, Perceived Stress, Experienced Stress, Females
{"title":"Experienced and Perceived Stress in Females With Schizophrenia and Healthy Subjects","authors":"M. Mogadam, M. Samadzadeh, B. Shahbazzadegan, Bita Movaffag","doi":"10.17795/BHS-34433","DOIUrl":"https://doi.org/10.17795/BHS-34433","url":null,"abstract":"Background: Schizophrenia is a psychiatric disorder characterized by chronic disturbances of thought and perception. \u0000Objectives: The current study aimed to compare perceived stress in females with schizophrenia and that of healthy people. \u0000Patients and Methods: The study sample included 50 patients with schizophrenia in Tuba rehabilitation center in Ardabil selected by available sampling method. Healthy group participants were selected through cloning by age, gender and marital status of the patient group. The data were collected by the questionnaire of Holmes-Rahe scale and Cohen et al. Data were analyzed by multivariate \u0000ANOVA (MANOVA) using SPSS software. \u0000Results: Compared with the normal subjects, patients with schizophrenia had a higher mean score in negative perceived and experienced stresses, but had a lower mean score in positive perceived stress as well as in total perceived stress. \u0000Conclusions: Results showed the levels of perceived stress and negative stress play important role in the creation and maintenance of schizophrenia. \u0000Keywords: Schizophrenia, Stress, Perceived Stress, Experienced Stress, Females","PeriodicalId":8849,"journal":{"name":"Biotechnology and Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75121776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: The food frequency questionnaire (FFQ) is a standard tool to assess long-term dietary intake. Development, reliability and validity of short FFQ depend on the study objective and population characteristics. However assessment of nutritional status of pregnant females is very important. Objectives: The current study aimed to examine the reliability and validity of a short food frequency questionnaire among pregnant females in the Qazvin, Iran. Patients and Methods: A total of 553 pregnant females, aged 18 - 40 years, during the third trimester of pregnancy, were included in the study. Statistical analysis of Pearson correlation coecient, analysis of covariance for logistic regression and factor analysis were performed using SPSS software version 23. Results: In this study, Pearson correlation coecients between test and retest for foods was r = 0.845. The Kaiser-Meyer-Oilskin measure of sampling adequacy was 0.584, P values for the Bartlett test of sphericity were all less than 0.001. Conclusions: The SFFQ has adequate reproducibility and validity for Iranian pregnant females.
{"title":"Reliability and Validity of Short Food Frequency Questionnaire Among Pregnant Females","authors":"S. F. Sharafi, M. Javadi, A. Barikani","doi":"10.17795/BHS-34608","DOIUrl":"https://doi.org/10.17795/BHS-34608","url":null,"abstract":"Background: The food frequency questionnaire (FFQ) is a standard tool to assess long-term dietary intake. Development, reliability and validity of short FFQ depend on the study objective and population characteristics. However assessment of nutritional status of pregnant females is very important. Objectives: The current study aimed to examine the reliability and validity of a short food frequency questionnaire among pregnant females in the Qazvin, Iran. Patients and Methods: A total of 553 pregnant females, aged 18 - 40 years, during the third trimester of pregnancy, were included in the study. Statistical analysis of Pearson correlation coecient, analysis of covariance for logistic regression and factor analysis were performed using SPSS software version 23. Results: In this study, Pearson correlation coecients between test and retest for foods was r = 0.845. The Kaiser-Meyer-Oilskin measure of sampling adequacy was 0.584, P values for the Bartlett test of sphericity were all less than 0.001. Conclusions: The SFFQ has adequate reproducibility and validity for Iranian pregnant females.","PeriodicalId":8849,"journal":{"name":"Biotechnology and Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77709506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Bazi, E. Miri-Moghaddam, Daryoush Rostami, M. Dabirzadeh
Background: Hepatitis is a serious blood born infection in patients with β-thalassemia major (β-TM). There was no previous report on hepatitis prevalence in patients with β-TM in Zabol, Iran. Objectives: The current study aimed to evaluate characteristics of hepatitis in patients with ᵝ-TM visiting Imam Khomeini Hospital of Zabol, in Sistan and Baluchistan province of Iran. Patients and Methods: There were 90 patients with ᵝ-TM. General demographic and laboratory results were obtained by interviews and reviewing clinical and laboratory histories. Data for anti-HCV, HBs antigen and anti-HBs were extracted from latest archived records, and analyzed using SPSS ver. 19. Results: Males and females comprised 51% and 49% of the patients, respectively. Mean age of the patients was 14.8±7.4 years old. Anti-HCV and HBs antigen were detected in 10% and 3.3% of the patients, respectively. Significant difference was found between the mean age of anti-HCV positive (20.1 ± 3.6, 95% CI: 17.3 - 22.9) and negative (14.2 ± 7.5, 95% CI: 12.5 - 15.9) patients (P = 0.02). Mean ferritin value was measured 4702 ± 2743 ng/mL. A significant correlation was observed between serum ferritin level and age (r = 0.3, P = 0.01). Hepatic enzymes, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) had mean levels of 51.8 ± 32.8 IU/L and 58.8 ± 59 IU/L, respectively. No significant association was identified between hepatitis status and either ferritin or hepatic enzymes levels. Conclusions: Results demonstrated the relatively high prevalence of HCV infection in the patients. Applying sensitive methods to screen blood units is recommended to minimize the risk of transfusion associated hepatitis. Keywords: β-Thalassemia Major, Anti-HCV, HBs Antigen, Anti-HBs, Ferritin
{"title":"Characteristics of Seropositive Hepatitis B and C Thalassemia Major Patients in South-East of Iran","authors":"A. Bazi, E. Miri-Moghaddam, Daryoush Rostami, M. Dabirzadeh","doi":"10.17795/BHS-35687","DOIUrl":"https://doi.org/10.17795/BHS-35687","url":null,"abstract":"Background: Hepatitis is a serious blood born infection in patients with β-thalassemia major (β-TM). There was no previous report on hepatitis prevalence in patients with β-TM in Zabol, Iran. \u0000Objectives: The current study aimed to evaluate characteristics of hepatitis in patients with ᵝ-TM visiting Imam Khomeini Hospital of Zabol, in Sistan and Baluchistan province of Iran. \u0000Patients and Methods: There were 90 patients with ᵝ-TM. General demographic and laboratory results were obtained by interviews and reviewing clinical and laboratory histories. Data for anti-HCV, HBs antigen and anti-HBs were extracted from latest archived records, and analyzed using SPSS ver. 19. \u0000Results: Males and females comprised 51% and 49% of the patients, respectively. Mean age of the patients was 14.8±7.4 years old. Anti-HCV and HBs antigen were detected in 10% and 3.3% of the patients, respectively. Significant difference was found between the \u0000mean age of anti-HCV positive (20.1 ± 3.6, 95% CI: 17.3 - 22.9) and negative (14.2 ± 7.5, 95% CI: 12.5 - 15.9) patients (P = 0.02). Mean ferritin value was measured 4702 ± 2743 ng/mL. A significant correlation was observed between serum ferritin level and age (r = 0.3, P = 0.01). Hepatic enzymes, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) had mean levels of 51.8 ± 32.8 IU/L and 58.8 ± 59 IU/L, respectively. No significant association was identified between hepatitis status and either ferritin or hepatic enzymes levels. \u0000Conclusions: Results demonstrated the relatively high prevalence of HCV infection in the patients. Applying sensitive methods to screen blood units is recommended to minimize the risk of transfusion associated hepatitis. \u0000Keywords: β-Thalassemia Major, Anti-HCV, HBs Antigen, Anti-HBs, Ferritin","PeriodicalId":8849,"journal":{"name":"Biotechnology and Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79220164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Najafipour, J. Ansari, Manijeh Jalilvand, S. Moghbelinejad
Background: Chromosomal abnormality plays an important role in different types of miscarriages. Objectives: The present study was designed to investigation chromosomal anomalies in three groups of couples with recurrent abortion (RA), spontaneous abortion (SA) and still birth (SB). PatientsandMethods: In this retrospective study, the frequency of chromosomal aberrations was investigatedamong 260 couples with miscarriage, which had referred to the cytogenetic section of a reference laboratory in Buali hospilal, Qazvin, Iran from 2009 to 2014. Metaphase spreads were analyzed using G-banding. Results: In this study, 7.6% of couples had chromosomal aberrations including, balanced reciprocal translocations, robertsonian translocations, inversions and sex chromosome aneuploidy. Frequency of balanced translocations was higher, specifically in couples with SA. Conclusions: In this investigation we showed that chromosomal abnormalities could be one of the important causes of miscarriages. Cytogenetic evaluation of couples, which experienced different types of miscarriage, may prevent unnecessary treatments. Keywords: Recurrent Abortion, Spontaneous Abortion, Still Birth, Chromosome Abnormality
{"title":"Cytogenetic Evaluation of Couples With Spontaneous Abortion, Still Birth and Recurrent Miscarriage in Qazvin: Report and Review","authors":"R. Najafipour, J. Ansari, Manijeh Jalilvand, S. Moghbelinejad","doi":"10.17795/BHS-35388","DOIUrl":"https://doi.org/10.17795/BHS-35388","url":null,"abstract":"Background: Chromosomal abnormality plays an important role in different types of miscarriages. \u0000Objectives: The present study was designed to investigation chromosomal anomalies in three groups of couples with recurrent \u0000abortion (RA), spontaneous abortion (SA) and still birth (SB). \u0000PatientsandMethods: In this retrospective study, the frequency of chromosomal aberrations was investigatedamong 260 couples \u0000with miscarriage, which had referred to the cytogenetic section of a reference laboratory in Buali hospilal, Qazvin, Iran from 2009 \u0000to 2014. Metaphase spreads were analyzed using G-banding. \u0000Results: In this study, 7.6% of couples had chromosomal aberrations including, balanced reciprocal translocations, robertsonian \u0000translocations, inversions and sex chromosome aneuploidy. Frequency of balanced translocations was higher, specifically in couples \u0000with SA. \u0000Conclusions: In this investigation we showed that chromosomal abnormalities could be one of the important causes of miscarriages. \u0000Cytogenetic evaluation of couples, which experienced different types of miscarriage, may prevent unnecessary treatments. \u0000Keywords: Recurrent Abortion, Spontaneous Abortion, Still Birth, Chromosome Abnormality","PeriodicalId":8849,"journal":{"name":"Biotechnology and Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90945736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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