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Happiness Among College Students: A Cross-Sectional Web-Based Study Among Iranian Medical Students 大学生幸福感:伊朗医学生的网络横断面研究
Pub Date : 2016-03-01 DOI: 10.17795/BHS-36029
Azadeh Lesani, A. Mohammadpoorasl, M. Javadi, H. Ansari, A. Fakhari
Background: During the recent decades, happiness and psychological wellbeing have been among the most attractive issues for researchers in the fields of social sciences and health. Medical and paramedical students in comparison with other college students are less happy due to work circumstance in hospital and special education. Objectives: The aim of the present study was to evaluate happinessamongcollege students of Qazvin University of Medical Sciences in terms of socio-demographic variables. Materials and Methods: In this cross-sectional web-based study, all the students of Qazvin University of Medical Sciences in Iran who had course classes were invited to participate in the study and 541 students filled out the web-based questionnaire including questions for measuring happiness oxford happiness questionnaire (OHQ), health status, stress experience in the past six months, cigarette and hookah smoking, physical activity rapid assessment of physical activity (RAPA), as well as socio-economic and demographic information. Results: The mean happiness score was 114.59 ± 18.31. Socio-economic status, physical activity, and experience of stress in the last 6 months were related to the happiness score (P = 0.009, P < 0.001, P < 0.001, respectively). However, gender, cigarette smoking, hookah smoking and body mass index were not significantly correlated with happiness. Conclusions: The findings of the present study show that a happiness score among our sample study was slightly low and people with high happiness scores had a healthier lifestyle, i.e. more physical activity and less tobacco smoking. College students should be encouraged to do regular exercise as a way to increase the happiness level. Keywords: Happiness, Tobacco Smoking, Life Satisfaction, Physical Activity, Students
近几十年来,幸福和心理健康一直是社会科学和健康领域研究人员最感兴趣的问题之一。受医院工作环境和特殊教育的影响,医、准医学生的幸福感较普通大学生低。目的:本研究旨在以社会人口学变量评估加兹温医科大学大学生的幸福感。材料与方法:在本横断面网络研究中,邀请伊朗Qazvin医科大学所有有课程的学生参与研究,541名学生填写了基于网络的问卷,问卷内容包括幸福测量牛津幸福问卷(OHQ)、健康状况、过去六个月的压力经历、吸烟和水烟、体育活动快速评估(RAPA)、以及社会经济和人口信息。结果:幸福感平均得分为114.59±18.31。社会经济地位、最近6个月的体力活动和压力经历与幸福感得分相关(P = 0.009, P < 0.001, P < 0.001)。然而,性别、吸烟、吸水烟和体重指数与幸福感没有显著相关。结论:本研究的结果表明,我们的样本研究中的幸福得分略低,幸福得分高的人有更健康的生活方式,即更多的体育锻炼和更少的吸烟。应该鼓励大学生经常锻炼身体,以此来提高幸福感。关键词:幸福感,吸烟,生活满意度,体育锻炼,学生
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引用次数: 16
A STUDY OF THE UNSAFE ACTIONS OF STAFF IN THE MAINTENANCE AND OVERHAUL UNIT AT A PETROCHEMICAL COMPLEX AND THE PRESENTATION OF CONTROL STRATEGIES 某石化企业维修大修机组人员不安全行为的研究及控制策略的提出
Pub Date : 2016-02-22 DOI: 10.17795/BHS-32561
S. Mousavipour, Ali Safary Variani, R. Mirzaei
Background: Today, oil, gas, and petrochemical industries are of strategic significance in the macro-development of oil-rich countries. These industries, given the nature of the work and the technical complexity of the various processes, are hazardous and susceptible to occupational accidents. More than 90% of the accidents are related to the faults and unsafe actions of personnel, either directly or indirectly. Objectives: The aim of this study is to investigate the unsafe actions of staff working in the maintenance unit of a petrochemical complex. Materials and Methods: This is a descriptive and analytical study conducted on 167 morning-shift workers at the Mahshahr petrochemical complex. The data were collected based on a checklist of unsafe actions prepared through a direct observation of their activities and an analysis of work instructions, documents, and incident reports. SPSS statistical software was also used for data analysis and relevant testing. Results: According to the results of this study, the mean number of unsafe actions performed by the employees was 42%. The highest number of unsafe actions achieved in the maintenance mechanical unit was 52.8%, 47.1% in repair services, and 43.8% in machinery. The highest frequency of unsafe actions were caused by indiscretion and negligence, a failure to use a face shield and goggles, and noncompliance with safety principles. Conclusions: According to the findings, there has been a rise in the number of unsafe actions in machinery and maintenance service units compared to other maintenance units. As such, training courses based on the behavior-based safety principles at the beginning of employment, close monitoring of health safety environment (HSE) officials on the implementation of regulations, and provision of appropriate scheduling based on weather conditions and the nature of maintenance services are recommended. In addition, a refrainment from hastiness in performing duties, enhanced participation from the employees to improve occupational safety, and the production and distribution of high-quality personal protective equipment (PPE) is also recommended to mitigate unsafe actions.
背景:当今,石油、天然气和石化产业在富油国家的宏观发展中具有战略意义。由于这些行业的工作性质和各种工艺的技术复杂性,这些行业是危险的,容易发生职业事故。90%以上的事故直接或间接地与人员的过失和不安全行为有关。目的:本研究的目的是调查工作人员的不安全行为,在一个石化综合设施的维修单位。材料与方法:这是一项对Mahshahr石化总厂167名早班工人进行的描述性和分析性研究。数据的收集是基于通过直接观察他们的活动和对工作指示、文件和事件报告的分析而准备的不安全行为清单。并采用SPSS统计软件进行数据分析和相关检验。结果:根据本研究的结果,员工进行不安全行为的平均次数为42%。维修机械部门的不安全行为发生率最高,为52.8%,维修服务部门为47.1%,机械部门为43.8%。不安全行为的最高频率是由轻率和疏忽、未使用面罩和护目镜以及不遵守安全原则引起的。结论:根据调查结果,与其他维修单位相比,机械和维修服务单位的不安全行为数量有所增加。因此,建议在就业之初开展基于行为安全原则的培训课程,密切监测健康安全环境(HSE)官员对法规的执行情况,并根据天气条件和维修服务的性质提供适当的调度。此外,还建议避免匆忙履行职责,加强员工的参与以改善职业安全,以及生产和分发高质量的个人防护装备(PPE),以减少不安全行为。
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引用次数: 3
Maternal Parity and Blood Oxidative Stress in Mother and Neonate 母亲和新生儿的胎次和血液氧化应激
Pub Date : 2016-02-22 DOI: 10.17795/BHS-34165
Faegheh Golalizadeh, F. Shobeiri, A. Ranjbar, M. Nazari
Background: Parturition has been associated with free radicals, itself linked with poor pregnancy outcome. Objectives: This study aimed to investigate the relationship between oxidative stress biomarkers levels of maternal and cord blood samples at the second stage of labor with the maternal parity number. Materials and Methods: In this analytical cross-sectional study, subjects were selected from Fatemieh teaching hospital, Hamadan, Iran, and allocated into the two groups according to their number of parity: the primiparous group (n = 33), and multiparous group (n = 35). Maternal and umbilical cord blood samples were taken from all subjects and then assessed for catalas activity (CAT), total thiol molecules (TTM) and total antioxidant capacity (TAC). Results: Total antioxidant capacity levels were significantly higher in newborns of primiparous women compared to multiparous women (P = 0.006). The CAT levels were significantly lower (P = 0.04) and TAC levels significantly higher (P = 0.03) in maternal plasma of primiparous women compared to those of multiparous women. Conclusions: Increment in the number of parity can lead to decrease antioxidant defense mechanisms in multiparous women and their newborns. So, control of oxidative stress is considered to be beneficial in multiparous women. Keywords: Oxidative Stress, Antioxidants, Parity
背景:分娩与自由基有关,自由基本身与妊娠结局不良有关。目的:本研究旨在探讨分娩第二阶段母体和脐带血样本氧化应激生物标志物水平与产妇产次的关系。材料与方法:本分析性横断面研究从伊朗Hamadan的Fatemieh教学医院选取受试者,按产次分为两组:初产组(n = 33)和多产组(n = 35)。采集所有受试者的母体和脐带血样本,然后评估过氧化氢酶活性(CAT)、总硫醇分子(TTM)和总抗氧化能力(TAC)。结果:初产妇女新生儿的总抗氧化能力水平明显高于多产妇女(P = 0.006)。初产妇女血浆中CAT水平显著低于多产妇女(P = 0.04), TAC水平显著高于多产妇女(P = 0.03)。结论:产次增加可导致多胎妇女及其新生儿抗氧化防御机制降低。因此,控制氧化应激被认为对多胎妇女有益。关键词:氧化应激,抗氧化剂,平价
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引用次数: 7
The Relationship Between Strategic Thinking and Hospital Managers' Productivity in Teaching Hospitals of Shiraz 设拉子地区教学医院战略思维与医院管理者生产力的关系
Pub Date : 2016-02-22 DOI: 10.17795/BHS-33795
M. Kiaei, N. Hatam, Mina Moraveji, R. Moradi, M. Ahmadzadeh, S. Ghanavati
Background: Using different methods of strategic thinking is essential for organizations such as hospitals; without them, many organizations will not survive. The aim of the present study is to evaluate the relationship between strategic thinking and management productivity in teaching hospitals of Shiraz. Objectives: Because of the importance of strategic management in organizational productivity, the present study is conducted with the goal of assessing the relationship between strategic thinking and hospital managers’ productivity. Patients and Methods: This descriptive-correlational study was conducted in 2015. The statistical population included all managers in different levels in the teaching hospitals of Shiraz (170 persons). Among these, 119 participants were selected through Cochran’s formula and a simple random sampling method. Data were collected by a questionnaire addressing strategic thinking based on Liedtka’s model and Hersey and Blanchard’s theory. Its validity was verified by a panel of experts and its reliability was measured in previous studies. Data analysis was performed in SPSS version 20 using descriptive and analytic statistics (analysis of variance (ANOVA), Pearson’s correlation test and t-test). Results: The average and Standard Deviation of strategic thinking managers was (2.2 ± 0.04), and productivity of management (2.32 ± 0.37) was estimated on the average level. There was a direct meaningful relationship between strategically thinking managers and productivity (r = 0.387, P < 0.001). The results also showed that there is a meaningful correlation between strategic thinking and sustainability, organizational support and understanding of the job. Conclusions: Due to the correlation between strategic thinking and productivity, we recommend educating and training managers in the use of strategic thinking, and that they understand its importance to productivity. Managers should understand that increasing efficiency in a competitive environment today is a necessity for survival.
背景:使用不同的战略思维方法对医院等组织至关重要;没有他们,许多组织将无法生存。本研究旨在探讨设拉子地区教学医院的战略思维与管理生产力的关系。目的:由于战略管理在组织生产力中的重要性,本研究旨在评估战略思维与医院管理者生产力之间的关系。患者和方法:本描述性相关研究于2015年进行。统计人群为设拉子省教学医院各级管理人员170人。其中,通过Cochran公式和简单随机抽样法选取119名参与者。数据的收集是基于Liedtka的模型和Hersey和Blanchard的理论的战略思维的问卷调查。其有效性已由专家小组验证,其可靠性已在先前的研究中测量。使用SPSS version 20进行数据分析,采用描述性统计和分析统计(方差分析(ANOVA)、Pearson相关检验和t检验)。结果:战略思维管理者的均值和标准差为(2.2±0.04),管理生产率为(2.32±0.37),处于平均水平。具有战略思维的管理者与生产力之间存在直接的有意义的关系(r = 0.387, P < 0.001)。结果还表明,战略思维与可持续性、组织支持和工作理解之间存在有意义的相关关系。结论:由于战略思维与生产力之间的相关性,我们建议教育和培训管理人员使用战略思维,并且他们了解战略思维对生产力的重要性。管理者应该明白,在当今竞争激烈的环境中提高效率是生存的必要条件。
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引用次数: 6
Viewpoints of Patients in Qazvin Towards Complementary and Alternative Medicine 卡兹温患者对补充和替代医学的看法
Pub Date : 2016-02-22 DOI: 10.17795/BHS-28324
A. Barikani, A. Beheshti, M. Javadi, S. Farahani, Firooz Barikani
Background: We have little information on the degree of individuals’ in Iran and their use of complementary and alternative medicine, its variations and the causes of people’s tendency towards the treatments used in the methods mentioned above. Objectives: In 2012, we set out to study the viewpoints of patients in Qazvin, Iran, examining how they feel about complementary and alternative medicine. Patients and Methods: In a cross-sectional study, data were collected through the use of a questionnaire. A total of 293 patients who had been referred to the complementary and alternative medicine centers were surveyed. These centers practice methods such as cupping, homeopathy and acupuncture. The questionnaire was divided in two parts, demographic questions and main questions, in this particular study. The data were analyzed using SPSS software version 19 with P < 0.05. Results: The mean age of the participants was 37.2 ± 13.3, and 60.8 percent of them were men. In all, 70.6 percent and 24.4 percent of respondents were married and single, respectively. About 58 percent had completed their undergraduate education. The cause of 31.3 percent of the participants’ visits was mental sicknesses, 20.2 percent attended due to rheumatologic diseases, and 8.2 percent applied to the mentioned treatment centers seeking relief from skin-related diseases. Ninety-one percent of the participants reported using alternative and complementary medicine for its efficiency. The levels of high satisfaction they reported gaining from the center’s homeopathy, acupuncture, and phlebotomy services were 17.2%, 16.5%, and 18.2%, respectively. In addition, 70 percent of the patients found the new treatment method to be quite successful, while 27 percent found it to be less effective than other approaches they had tried. Conclusions: The people were receptive to the use of alternative and complementary medicine and their satisfaction level was high. Keywords: Homeopathy, Acupuncture, Phlebotomy
背景:我们几乎没有关于伊朗个人的程度及其对补充和替代医学的使用、其差异以及人们倾向于上述方法中使用的治疗方法的原因的信息。目的:2012年,我们开始研究伊朗加兹文(Qazvin)患者的观点,调查他们对补充和替代医学的看法。患者和方法:在横断面研究中,通过使用问卷收集数据。共有293名患者被转介到补充和替代医学中心进行了调查。这些中心采用拔火罐、顺势疗法和针灸等方法。问卷分为两部分,人口统计问题和主要问题,在这个特殊的研究。数据分析采用SPSS 19版软件,P < 0.05。结果:参与者的平均年龄为37.2±13.3岁,男性占60.8%。其中,70.6%的人已婚,24.4%的人单身。大约58%的人完成了本科教育。31.3%的参与者因精神疾病就诊,20.2%因风湿病就诊,8.2%因皮肤相关疾病到上述治疗中心就诊。91%的参与者报告使用替代和补充药物的效率。他们报告从该中心的顺势疗法、针灸和放血服务中获得的高满意度分别为17.2%、16.5%和18.2%。此外,70%的患者认为这种新的治疗方法非常成功,而27%的患者认为它不如他们尝试过的其他方法有效。结论:患者对替代和补充医学的接受程度较高,满意度较高。关键词:顺势疗法,针灸,放血
{"title":"Viewpoints of Patients in Qazvin Towards Complementary and Alternative Medicine","authors":"A. Barikani, A. Beheshti, M. Javadi, S. Farahani, Firooz Barikani","doi":"10.17795/BHS-28324","DOIUrl":"https://doi.org/10.17795/BHS-28324","url":null,"abstract":"Background: We have little information on the degree of individuals’ in Iran and their use of complementary and alternative medicine, its variations and the causes of people’s tendency towards the treatments used in the methods mentioned above. \u0000Objectives: In 2012, we set out to study the viewpoints of patients in Qazvin, Iran, examining how they feel about complementary and alternative medicine. \u0000Patients and Methods: In a cross-sectional study, data were collected through the use of a questionnaire. A total of 293 patients who had been referred to the complementary and alternative medicine centers were surveyed. These centers practice methods such as cupping, homeopathy and acupuncture. The questionnaire was divided in two parts, demographic questions and main questions, in this particular study. The data were analyzed using SPSS software version 19 with P < 0.05. \u0000Results: The mean age of the participants was 37.2 ± 13.3, and 60.8 percent of them were men. In all, 70.6 percent and 24.4 percent of respondents were married and single, respectively. About 58 percent had completed their undergraduate education. The cause of 31.3 percent of the participants’ visits was mental sicknesses, 20.2 percent attended due to rheumatologic diseases, and 8.2 percent applied to the mentioned treatment centers seeking relief from skin-related diseases. Ninety-one percent of the participants reported using alternative and complementary medicine for its efficiency. The levels of high satisfaction they reported gaining from the center’s homeopathy, acupuncture, and phlebotomy services were 17.2%, 16.5%, and 18.2%, respectively. In addition, 70 percent of the patients found the new treatment method to be quite successful, while 27 percent found it to be less effective than other approaches they had tried. \u0000Conclusions: The people were receptive to the use of alternative and complementary medicine and their satisfaction level was high. \u0000Keywords: Homeopathy, Acupuncture, Phlebotomy","PeriodicalId":8849,"journal":{"name":"Biotechnology and Health Sciences","volume":"19 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2016-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76573193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Comparison of Cardiovascular Risk Factors Between Subjects With and Without Diabetes Mellitus: An Analytical Study 糖尿病患者与非糖尿病患者心血管危险因素比较:一项分析性研究
Pub Date : 2016-02-22 DOI: 10.17795/BHS-34330
A. Mousavi, S. Asefzadeh, A. Ziaee, N. Esmailzadehha, A. Ghorbani
Background: Cardiovascular Disease (CVD) is developing treacherously along industrialization and development of urbanization Objectives: The aim of this study was to compare cardiovascular risk factors between subjects with and without diabetes mellitus in the Minoodar district of Qazvin. Patients and Methods: This analytical study was conducted on 100 subjects with diabetes and 140 subjects without diabetes in Qazvin from September 2010 to April 2011. Standardized measurements were available for waist circumference (WC), blood pressure (BP), fasting serum cholesterol, high-density lipoprotein cholesterol (HDL), and triglycerides (TGs). Cardiovascular risk factors were defined according to the diagnostic criteria proposed by the national cholesterol education program. Data were analyzed using the t-test, Mann-Whitney U test, and Chi-square test. Results: Overall, 12% of subjects with diabetes and 17.9% of subjects without diabetes were smokers (P = 0.277). The WC, TGs, systolic and diastolic BP were significantly higher in subjects with diabetes compared to subjects without diabetes. The prevalence of high WC, high BP, low HDL, and high TGs were significantly higher in subjects with diabetes compared to subjects without diabetes. Conclusions: Cardiovascular risk factors were higher in subjects with diabetes compared to subjects without diabetes. Lifestyle intervention programs should be focused on community education about reduction of CVD risk factors in patients with diabetes. Keywords: Risk Factor, Coronary Heart Disease, Diabetes Mellitus
背景:随着工业化和城市化的发展,心血管疾病(CVD)正在迅速发展。目的:本研究的目的是比较加兹温Minoodar地区糖尿病患者和非糖尿病患者的心血管危险因素。患者与方法:本分析研究于2010年9月至2011年4月在加兹温市对100名糖尿病患者和140名非糖尿病患者进行研究。腰围(WC)、血压(BP)、空腹血清胆固醇、高密度脂蛋白胆固醇(HDL)和甘油三酯(tg)均可进行标准化测量。根据国家胆固醇教育计划提出的诊断标准确定心血管危险因素。数据分析采用t检验、Mann-Whitney U检验和卡方检验。结果:总体而言,12%的糖尿病患者和17.9%的非糖尿病患者是吸烟者(P = 0.277)。糖尿病患者的WC、tg、收缩压和舒张压明显高于非糖尿病患者。糖尿病患者的高WC、高BP、低HDL和高tg患病率明显高于非糖尿病患者。结论:糖尿病患者的心血管危险因素高于非糖尿病患者。生活方式干预项目应侧重于减少糖尿病患者心血管疾病危险因素的社区教育。关键词:危险因素,冠心病,糖尿病
{"title":"Comparison of Cardiovascular Risk Factors Between Subjects With and Without Diabetes Mellitus: An Analytical Study","authors":"A. Mousavi, S. Asefzadeh, A. Ziaee, N. Esmailzadehha, A. Ghorbani","doi":"10.17795/BHS-34330","DOIUrl":"https://doi.org/10.17795/BHS-34330","url":null,"abstract":"Background: Cardiovascular Disease (CVD) is developing treacherously along industrialization and development of urbanization \u0000Objectives: The aim of this study was to compare cardiovascular risk factors between subjects with and without diabetes mellitus in the Minoodar district of Qazvin. \u0000Patients and Methods: This analytical study was conducted on 100 subjects with diabetes and 140 subjects without diabetes in Qazvin from September 2010 to April 2011. Standardized measurements were available for waist circumference (WC), blood pressure (BP), fasting serum cholesterol, high-density lipoprotein cholesterol (HDL), and triglycerides (TGs). Cardiovascular risk factors were defined according to the diagnostic criteria proposed by the national cholesterol education program. Data were analyzed using the t-test, Mann-Whitney U test, and Chi-square test. \u0000Results: Overall, 12% of subjects with diabetes and 17.9% of subjects without diabetes were smokers (P = 0.277). The WC, TGs, systolic and diastolic BP were significantly higher in subjects with diabetes compared to subjects without diabetes. The prevalence of high WC, high BP, low HDL, and high TGs were significantly higher in subjects with diabetes compared to subjects without diabetes. \u0000Conclusions: Cardiovascular risk factors were higher in subjects with diabetes compared to subjects without diabetes. Lifestyle intervention programs should be focused on community education about reduction of CVD risk factors in patients with diabetes. \u0000Keywords: Risk Factor, Coronary Heart Disease, Diabetes Mellitus","PeriodicalId":8849,"journal":{"name":"Biotechnology and Health Sciences","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85210532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Frequency of Fibronectin Binding Protein A and Panton-Valentine Leukocidin in Methicillin-Resistant Staphylococcus aureus Collected From Educational Hospitals in Qazvin, Iran 伊朗加兹温教育医院耐甲氧西林金黄色葡萄球菌中纤维连接蛋白结合蛋白A和潘通-瓦伦丁白介素的频率
Pub Date : 2016-02-22 DOI: 10.17795/BHS-35939
Maria Taromian, A. Peymani, M. Aslanimehr
Background: Staphylococcus aureus is one of the most important organisms involved in nosocomial infection acquired by patients. In recent years, the appearance of methicillin-resistant S. aureus (MRSA) has turned the treatment of these infections into a serious challenge. Surface proteins, such as fibronectin binding proteins (FnBP), and the ability to produce Panton-Valentine leukocidin (PVL) are important factors in pathogenesis of this organism. Objectives: The purpose of this study was to determine the prevalence of disease-associated genes in the clinical isolates of S. aureus encoding FNB and PVL, collected from the educational hospitals of Qazvin, Iran. Patients and Methods: This was a descriptive, cross-sectional study in which a total of 103 isolates of methicillin-resistant S. aureus were collected from hospitalized patients in teaching hospitals of Qazvin, during 2013 - 2014. Initially, the identification of isolates was performed according to the standard laboratory methods, followed by confirming the presence of the femA gene, a gene specific to S. aureus. Later, the prevalence of virulence genes (fnb and pvl) was investigated by the PCR method, using specific primers. PCR products were sequenced to confirm the presence of the target genes. Results: The results of this study showed that among 103 isolates of S. aureus resistant to methicillin, 88 isolates were positive for the presence of the pvl and fnb genes, with the fnb gene present in 86 (83.5%) isolates and the pvl gene only in 2 (1.9%) isolates. Conclusions: The results of the present study indicate the presence of the pvl and fnb genes in the strains of S. aureus isolated from clinical specimens collected from the patients admitted to teaching hospitals in Qazvin. Considering the clinical significance of these organisms, and their potential in threatening public health systems, the identification, treatment, and infection control management of patients infected with these organisms is of prime necessity.
背景:金黄色葡萄球菌是引起患者院内感染的重要微生物之一。近年来,耐甲氧西林金黄色葡萄球菌(MRSA)的出现使这些感染的治疗成为一个严重的挑战。表面蛋白,如纤维连接蛋白结合蛋白(FnBP)和产生Panton-Valentine leukocidin (PVL)的能力是该生物发病的重要因素。目的:本研究的目的是确定从伊朗Qazvin教育医院收集的编码FNB和PVL的金黄色葡萄球菌临床分离株中疾病相关基因的患病率。患者和方法:这是一项描述性、横断面研究,从2013 - 2014年卡兹温教学医院住院患者中收集了103株耐甲氧西林金黄色葡萄球菌。最初,根据标准实验室方法对分离株进行鉴定,随后确认存在femA基因,这是金黄色葡萄球菌特有的基因。随后,利用特异性引物,采用PCR方法检测毒力基因(fnb和pvl)的流行情况。对PCR产物进行测序以确认目标基因的存在。结果:本研究结果显示,103株耐甲氧西林金黄色葡萄球菌中有88株pvl和fnb基因阳性,其中fnb基因在86株(83.5%)中存在,pvl基因仅在2株(1.9%)中存在。结论:本研究结果表明,从卡兹温省教学医院住院患者的临床标本中分离出的金黄色葡萄球菌存在pvl和fnb基因。考虑到这些微生物的临床意义及其对公共卫生系统的潜在威胁,对感染这些微生物的患者进行识别、治疗和感染控制管理是非常必要的。
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引用次数: 1
MUSCULOSKELETAL DISORDERS AND THEIR RELATED RISK FACTORS AMONG IRANIAN NURSES 伊朗护士的肌肉骨骼疾病及其相关危险因素
Pub Date : 2016-02-22 DOI: 10.17795/BHS-34473
H. Taghinejad, A. Azadi, Zainab Suhrabi, Mohammadreza Sayedinia
Background: Work-related musculoskeletal disorders (MSDs) are one of the most occupational problems among nurses and often cause many physical and psychological complications for nurses, and are a financial burden for health-care systems. Objectives: The aim of this study was to determine the prevalence MSDs and their related risk factors among Iranian nurses. Patients and Methods: This descriptive-correlational study included 240 hospital nurses, with a baccalaureate nursing degree, who worked at three public hospitals of the Ilam province of Iran. Data were collected through a validated self-administered questionnaire. Finally, 156 questionnaires were returned (response rate: 65%) and 135 questionnaires qualified for subsequent analysis. The data were analyzed using the SPSS version 15.0 software. Descriptive and inferential statistics (logistic regression) were used. Results: Overall, 97 (71.9%) hospital nurses experienced MSDs in at least one anatomical site within the last year. Low back pain was the most prevalent MSDs (40%) and hip and thigh were the least (11.1%) frequent sites. Most of the nurses with MSDs worked at surgery wards (17.8%), emergency (15.6%) and intensive care units (12.6%). Pain (48.1%) and cramps (31.9%) were the most frequent symptoms of MSDs and loss of limbs control (5.9%) was the least frequent symptom. Bend or twist at waist for performing nursing procedures, patient transfer from and to beds, working with the hands higher than shoulder height and changing position of patients in beds were the most frequent occupational factors that influenced MSDs. Increased age, weight, height, body mass index (BMI) and gender had no significant association with MSDs. However, being single and involved in any kinds of physical activity were significantly associated with the prevalence of MSDs (P < 0.05). Conclusions: The study findings indicated high prevalence of worked-related MSDs among Iranian hospital nurses. Accordingly, appropriate policies for managing MSDs among hospital nurses should be considered. Keywords: Musculoskeletal Disorders, Nurses,Workplace, Iran
背景:与工作相关的肌肉骨骼疾病(MSDs)是护士中最常见的职业问题之一,通常会导致护士的许多生理和心理并发症,并且是卫生保健系统的经济负担。目的:本研究的目的是确定伊朗护士的MSDs患病率及其相关危险因素。患者和方法:这项描述性相关研究包括240名医院护士,具有护理学士学位,在伊朗伊拉姆省的三家公立医院工作。通过有效的自我管理问卷收集数据。最终回收问卷156份(回复率65%),其中135份符合后续分析要求。采用SPSS 15.0版软件对数据进行分析。采用描述性统计和推理统计(逻辑回归)。结果:总体而言,97名(71.9%)医院护士在过去一年中至少在一个解剖部位经历过MSDs。腰痛是最常见的msd(40%),臀部和大腿是最不常见的部位(11.1%)。大多数有msd的护士在外科病房(17.8%)、急诊(15.6%)和重症监护病房(12.6%)工作。疼痛(48.1%)和痉挛(31.9%)是MSDs最常见的症状,肢体失去控制(5.9%)是最不常见的症状。在执行护理程序时腰部弯曲或扭转、患者在床上移动、双手高于肩高和患者在床上改变位置是影响MSDs最常见的职业因素。年龄、体重、身高、身体质量指数(BMI)和性别的增加与MSDs无显著相关。然而,单身和参加任何形式的体育活动与MSDs的患病率显著相关(P < 0.05)。结论:研究结果表明伊朗医院护士中与工作相关的msd患病率很高。因此,应考虑适当的政策来管理医院护士的msd。关键词:肌肉骨骼疾病,护士,工作场所,伊朗
{"title":"MUSCULOSKELETAL DISORDERS AND THEIR RELATED RISK FACTORS AMONG IRANIAN NURSES","authors":"H. Taghinejad, A. Azadi, Zainab Suhrabi, Mohammadreza Sayedinia","doi":"10.17795/BHS-34473","DOIUrl":"https://doi.org/10.17795/BHS-34473","url":null,"abstract":"Background: Work-related musculoskeletal disorders (MSDs) are one of the most occupational problems among nurses and often cause many physical and psychological complications for nurses, and are a financial burden for health-care systems. \u0000Objectives: The aim of this study was to determine the prevalence MSDs and their related risk factors among Iranian nurses. \u0000Patients and Methods: This descriptive-correlational study included 240 hospital nurses, with a baccalaureate nursing degree, who \u0000worked at three public hospitals of the Ilam province of Iran. Data were collected through a validated self-administered questionnaire. \u0000Finally, 156 questionnaires were returned (response rate: 65%) and 135 questionnaires qualified for subsequent analysis. The data were analyzed using the SPSS version 15.0 software. Descriptive and inferential statistics (logistic regression) were used. \u0000Results: Overall, 97 (71.9%) hospital nurses experienced MSDs in at least one anatomical site within the last year. Low back pain was the most prevalent MSDs (40%) and hip and thigh were the least (11.1%) frequent sites. Most of the nurses with MSDs worked at surgery wards \u0000(17.8%), emergency (15.6%) and intensive care units (12.6%). Pain (48.1%) and cramps (31.9%) were the most frequent symptoms of MSDs and loss of limbs control (5.9%) was the least frequent symptom. Bend or twist at waist for performing nursing procedures, patient transfer from and to beds, working with the hands higher than shoulder height and changing position of patients in beds were the \u0000most frequent occupational factors that influenced MSDs. Increased age, weight, height, body mass index (BMI) and gender had no significant association with MSDs. However, being single and involved in any kinds of physical activity were significantly associated with the prevalence of MSDs (P < 0.05). \u0000Conclusions: The study findings indicated high prevalence of worked-related MSDs among Iranian hospital nurses. Accordingly, appropriate policies for managing MSDs among hospital nurses should be considered. \u0000Keywords: Musculoskeletal Disorders, Nurses,Workplace, Iran","PeriodicalId":8849,"journal":{"name":"Biotechnology and Health Sciences","volume":"62 1","pages":"0-0"},"PeriodicalIF":0.0,"publicationDate":"2016-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80913017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 26
Impact of Functional Capacity on Nutritional Status of Hospitalized Elderly in Qazvin, Iran 功能能力对伊朗加兹温住院老年人营养状况的影响
Pub Date : 2016-02-22 DOI: 10.17795/BHS-34470
L. Dehghankar, A. Shahrokhi, S. Oveisi, N. Esmailzadehha, A. Ghorbani
Background: Lack of independence and unwanted dependence on others for activities of daily living (ADL) and decreased functional capacity affect nutritional status of the elderly. Objectives: The aim of this study was to determine the impact of functional capacity on malnutrition status in hospitalized elderly patients in the Qazvin city of Iran. Patients and Methods: This cross sectional study was conducted on patients 60 years or older hospitalized in two teaching hospitals of Qazvin, Iran, from May to October 2011. The nutritional status was assessed using the mini nutritional assessment (MNA) questionnaire. Functional capacity of the elderly was assessed using self-report questionnaires of ADL and Instrumental Activities of Daily Living (IADL). Data were analyzed using the Chi-square test and logistic regression analysis. Results: Of the 322 participant, 171 (53.1%) were male. The mean age was 70.36 ± 7.8 years. Based on MNA, 96 patients (29.8%) had normal nutritional status, 138 (42.9%) were at risk of malnutrition and 43 (13.4%) had malnutrition. Dependency on ADL and IADL was significantly associated with malnutrition and risk of malnutrition. In the logistic regression analysis, IADL was associated with malnutrition (OR: 1.19, 95% CI: 1.07 - 1.33; P < 0.001). Conclusions: Risk of malnutrition as well as reduced functional ability was high among the hospitalized elderly of Qazvin. Nutritional status assessment of older adults is necessary, particularly when they are admitted to hospitals.
背景:缺乏独立性和不必要的日常生活活动依赖他人(ADL)和功能能力下降影响老年人的营养状况。目的:本研究的目的是确定功能能力对伊朗加兹温市住院老年患者营养不良状况的影响。患者与方法:本横断面研究选取2011年5 - 10月在伊朗Qazvin两家教学医院住院的60岁及以上患者。采用微型营养评估问卷(MNA)对营养状况进行评估。采用日常生活自理能力(ADL)和日常生活工具活动(IADL)自述问卷对老年人的功能能力进行评估。数据分析采用卡方检验和logistic回归分析。结果:322名参与者中,男性171名,占53.1%。平均年龄70.36±7.8岁。根据MNA, 96例(29.8%)患者营养状况正常,138例(42.9%)存在营养不良风险,43例(13.4%)存在营养不良。对ADL和IADL的依赖与营养不良和营养不良风险显著相关。在logistic回归分析中,IADL与营养不良相关(OR: 1.19, 95% CI: 1.07 - 1.33;P < 0.001)。结论:卡兹温市住院老年人营养不良和功能下降的风险较高。对老年人的营养状况进行评估是必要的,特别是当他们住院时。
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引用次数: 5
Expression Analysis of ARMC3, a Testis-Specific Gene, in Breast Cancer Patients 睾丸特异性基因ARMC3在乳腺癌患者中的表达分析
Pub Date : 2016-02-17 DOI: 10.17795/BHS-34453
A. Zare, K. Majidzadeh-A, R. Esmaeili, N. Gheibi, M. Sarookhani
Background: Breast cancer is the most prevalent cancer among women. Biomarkers that are expressed in tumors play a pivotal role in diagnosis and treatment. Cancer-testis (CT) antigens are predominantly expressed in the testis and also have inappropriate expression in various tumor types. In the case of expression in tumors, they will be used as immunotherapy targets. Objectives: Expression of ARMC3, a CT antigen, was analyzed to determine its potential as a tumor marker for breast cancer. Materials and Methods: Eighty samples including 40 tumor samples and 40 normal adjacent tissue samples, were gathered from the ICBC biobank. RNA extraction was carried out on all samples. The extracted RNA was treated by DNaseI, after which cDNA was synthesized. Expression of ARMC3 with ACTB (internal control) was studied using Real-Time PCR (polymerase chain reaction). Results: Overall, 43.6% of tumors and 25.6% of normal adjacent tissues expressed ARMC3. ARMC3 was overexpressed in 41% of tumor samples (P = 0.00) and showed decreased expression in 46.2% (P = 0.00). Also, the expression of this gene in 12.8% of tumors was unchanged, which was statistically significant. It should be noted that all samples expressed ACTB gene. Conclusions: Expression of ARMC3 in tumor samples and normal adjacent tissue is very important. The expression of this gene in tumor-adjacent tissue may be associated with the stage of cancer; it may be that these tissues are affected by epigenetic and oncogenic changes of breast cancer. Accordingly, aberrant expression of ARMC3 in tumor samples may be an attractive candidate for use as a tumor marker.
背景:乳腺癌是女性中最常见的癌症。肿瘤中表达的生物标志物在诊断和治疗中起着关键作用。睾丸癌(CT)抗原主要在睾丸中表达,在各种肿瘤类型中也有不适当的表达。在肿瘤中表达的情况下,它们将被用作免疫治疗靶点。目的:ARMC3表达式,分析了CT抗原,以确定其潜在的作为乳腺癌的肿瘤标志物。材料与方法:从中国工商银行生物样本库中采集80份样本,包括40份肿瘤样本和40份正常邻近组织样本。对所有样品进行RNA提取。提取的RNA经DNaseI处理后合成cDNA。采用Real-Time PCR(聚合酶链反应)技术研究ARMC3与ACTB(内控)的表达。结果:总体而言,43.6%的肿瘤和25.6%的正常邻近组织表达ARMC3。ARMC3在41%的肿瘤样本中过表达(P = 0.00), 46.2%的肿瘤样本中表达降低(P = 0.00)。该基因在12.8%的肿瘤中表达不变,具有统计学意义。值得注意的是,所有样本均表达ACTB基因。结论:ARMC3在肿瘤及正常邻近组织中的表达具有重要意义。该基因在肿瘤邻近组织中的表达可能与肿瘤的分期有关;这可能是这些组织受到乳腺癌的表观遗传和致癌变化的影响。因此,肿瘤样本中ARMC3的异常表达可能是一个有吸引力的候选肿瘤标志物。
{"title":"Expression Analysis of ARMC3, a Testis-Specific Gene, in Breast Cancer Patients","authors":"A. Zare, K. Majidzadeh-A, R. Esmaeili, N. Gheibi, M. Sarookhani","doi":"10.17795/BHS-34453","DOIUrl":"https://doi.org/10.17795/BHS-34453","url":null,"abstract":"Background: Breast cancer is the most prevalent cancer among women. Biomarkers that are expressed in tumors play a pivotal \u0000role in diagnosis and treatment. Cancer-testis (CT) antigens are predominantly expressed in the testis and also have inappropriate \u0000expression in various tumor types. In the case of expression in tumors, they will be used as immunotherapy targets. \u0000Objectives: Expression of ARMC3, a CT antigen, was analyzed to determine its potential as a tumor marker for breast cancer. \u0000Materials and Methods: Eighty samples including 40 tumor samples and 40 normal adjacent tissue samples, were gathered from \u0000the ICBC biobank. RNA extraction was carried out on all samples. The extracted RNA was treated by DNaseI, after which cDNA was \u0000synthesized. Expression of ARMC3 with ACTB (internal control) was studied using Real-Time PCR (polymerase chain reaction). \u0000Results: Overall, 43.6% of tumors and 25.6% of normal adjacent tissues expressed ARMC3. ARMC3 was overexpressed in 41% of tumor \u0000samples (P = 0.00) and showed decreased expression in 46.2% (P = 0.00). Also, the expression of this gene in 12.8% of tumors was \u0000unchanged, which was statistically significant. It should be noted that all samples expressed ACTB gene. \u0000Conclusions: Expression of ARMC3 in tumor samples and normal adjacent tissue is very important. The expression of this gene \u0000in tumor-adjacent tissue may be associated with the stage of cancer; it may be that these tissues are affected by epigenetic and \u0000oncogenic changes of breast cancer. Accordingly, aberrant expression of ARMC3 in tumor samples may be an attractive candidate \u0000for use as a tumor marker.","PeriodicalId":8849,"journal":{"name":"Biotechnology and Health Sciences","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91234839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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Biotechnology and Health Sciences
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