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Cochran’s Q-Test on Soil Helminth Prevalence 土壤蠕虫流行率的Cochran q检验
Pub Date : 2021-12-01 DOI: 10.2478/bile-2021-0013
I. J. David, M. Adehi, P. O. Ikwuoche
Summary A study was made of the prevalence of nine geohelminth egg types in 184 soil samples from 16 recreational parks in Abuja metropolis, Nigeria. Cochran’s Q-test was applied to determine whether the difference in the proportions of the egg types found in the soil samples was significant. At a 5% significance level, it was found that the prevalence of the egg types was significantly different in the 184 soil samples from 16 parks. To identify which of the geohelminth eggs had a significantly larger mean proportional prevalence, a minimum required difference mean comparison technique was applied. The mean comparison test showed that Taenia and Coccocidia eggs were highly prevalent, with significantly larger mean proportions than the other analyzed geohelminth eggs in the 184 examined soil samples.
摘要对尼日利亚首都阿布贾16个休闲公园184份土壤样品中9种地蚓卵的流行情况进行了研究。科克伦的q测试是用来确定在土壤样本中发现的鸡蛋类型的比例差异是否显著。在5%显著水平下,16个公园184份土壤样品的卵型流行率存在显著差异。为了确定哪些地虱卵具有显著较大的平均比例流行率,应用了最小要求差均值比较技术。平均比较试验表明,带绦虫和球虫虫卵在184份土壤样品中高度流行,其平均比例显著高于其他种类的虫卵。
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引用次数: 0
Influence of different sowing density in two varieties of maize. Part II. Relation to agricultural morphological features 不同播种密度对两个玉米品种产量的影响。第二部分。与农业形态特征的关系
Pub Date : 2021-12-01 DOI: 10.2478/bile-2021-0016
P. Szulc, K. Ambroży-Deręgowska
Summary In this paper, we investigate the effect of seeding density on several morphological features such as plant height, height of the production ears, ear length, ear diameter, leaf area, and LAI (leaf area index). Inference is based on a series of three-year two-factor experiments with two hybrid maize varieties – SY Cooky and Drim “stay-green” type – and 5 sowing densities: 6, 7, 8, 9 and 10 plants per m2. The “stay-green” maize variety had production cobs significantly higher on the plant, and had a thicker cob and a larger leaf assimilation area than the conventional variety. Increasing maize sowing density from 6 to 10 plants m−2 resulted in a linear decrease in cob length and diameter, while it increased the LAI. Significantly higher chlorophyll content, expressed in SPAD units, was found in the “stay-green” hybrid at the BBCH 67 stage in a wet (2012) and drier year (2014), compared with the traditional variety. This may indicate that such a variety is more tolerant to stress conditions.
摘要本文研究了播种密度对玉米株高、生产穗高、穗长、穗径、叶面积和叶面积指数的影响。这一推断是基于对两种杂交玉米品种SY Cooky和Drim“绿色”型进行的为期三年的双因素试验,以及5种播种密度:每平方米6、7、8、9和10株。“留绿”玉米品种在植株上的生产穗轴显著高于常规品种,穗轴较粗,叶片同化面积较大。玉米播种密度从6株m−2增加到10株m−2,穗轴长和直径呈线性减少,而LAI增加。与传统品种相比,在丰湿(2012)和干旱(2014)的BBCH 67期,“留绿”杂交品种的SPAD单位叶绿素含量显著高于传统品种。这可能表明这样的品种更能忍受压力条件。
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引用次数: 0
On sample size calculation in testing treatment efficacy in clinical trials 临床试验中检验疗效的样本量计算
Pub Date : 2021-12-01 DOI: 10.2478/bile-2021-0010
Rownak Jahan Tamanna, M. Alam, A. Hossain, M. H. R. Khan
Summary Sample size calculation is an integral part of any clinical trial design, and determining the optimal sample size for a study ensures adequate power to detect statistical significance. It is a critical step in designing a planned research protocol, since using too many participants in a study is expensive, exposing more subjects to the procedure. If a study is underpowered, it will be statistically inconclusive and may cause the whole protocol to fail. Amidst the attempt to maximize power and the underlying effort to minimize the budget, the optimization of both has become a significant issue in the determination of sample size for clinical trials in recent decades. Although it is hard to generalize a single method for sample size calculation, this study is an attempt to offer something that might be a basis for finding a permanent answer to the contradictions of sample size determination, by the use of simulation studies under simple random and cluster sampling schemes, with different sizes of power and type I error. The effective sample size is much higher when the design effect of the sampling method is smaller, particularly less than 1. Sample size increases for cluster sampling when the number of clusters increases.
样本量计算是任何临床试验设计的一个组成部分,确定研究的最佳样本量确保有足够的能力来检测统计显著性。这是设计一个有计划的研究方案的关键一步,因为在一项研究中使用太多的参与者是昂贵的,将更多的受试者暴露在这个过程中。如果一项研究的动力不足,它将在统计上不确定,并可能导致整个方案失败。在试图最大化权力和潜在的努力最小化预算中,这两者的优化已经成为近几十年来确定临床试验样本量的一个重要问题。虽然很难概括出一种计算样本量的单一方法,但本研究试图通过简单随机和聚类抽样方案下的模拟研究,在不同的功率大小和I型误差下,为找到确定样本量矛盾的永久答案提供一些基础。当抽样方法的设计效应较小,特别是小于1时,有效样本量要高得多。当集群数量增加时,集群抽样的样本量也会增加。
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引用次数: 1
Influence of different sowing density in two varieties of maize. Part I. Relation to yielding 不同播种密度对两个玉米品种产量的影响。第一部分与屈服的关系
Pub Date : 2021-12-01 DOI: 10.2478/bile-2021-0015
K. Ambroży-Deręgowska, P. Szulc
Summary A study was carried out to determine the effect of sowing density on the yield of maize of two different varieties. The field experiment was carried out in 2012–2014 at the Department of Agronomy of Poznań University of Life Sciences. The first-order factor was the variety: SY Cooky and Drim “stay-green”; the second-order factor was sowing density: 6, 7, 8, 9, 10 plants per m2. Weather conditions during the maize growing seasons significantly influenced the values of the studied traits. Significantly the lowest green mass yield of maize was obtained at the sowing density of 6 plants m−2, and the highest for 10 plants m−2. The “stay-green” variety significantly responded to an increase in sowing density with reduced fresh weight of leaf blades of a single plant compared with the conventional variety. This indicated highly effective photosynthesis with a lower plant density per unit area, which is also the basis for effective absorption of solar radiation for these maize varieties.
研究了播种密度对两个不同品种玉米产量的影响。田间试验于2012-2014年在波兹纳斯生命科学大学农学系进行。一阶因素是品种:SY Cooky和Drim“保持绿色”;第二级因子为播种密度:6、7、8、9、10株/ m2。玉米生长季节的气候条件对所研究性状的值有显著影响。播种密度为6株m−2时,玉米青色质量产量最低,播种密度为10株m−2时青色质量产量最高。与常规品种相比,“留绿”品种对播种密度的增加和单株叶片鲜重的减少有显著的响应。这说明光合作用效率高,单位面积密度低,这也是这些玉米品种有效吸收太阳辐射的基础。
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引用次数: 1
Asymmetry models based on ordered score and separations of symmetry model for square contingency tables 基于有序分值的非对称模型和方形列联表对称模型的分离
Pub Date : 2021-06-01 DOI: 10.2478/bile-2021-0002
S. Ando
Summary This study proposes two original asymmetry models based on ordered scores for square contingency tables with the same row and column ordinal classifications. The proposed models can be applied to cases in which the scores of all categories are known or unknown. In the proposed models, the log odds for an observation falling in the (i, j)th cell instead of the (j, i)th cell are inversely proportional to the difference of the ordered scores corresponding to categories i and j. The asymmetry parameter of the proposed model can be useful for inferring whether the row variable is stochastically greater than the column variable or vice versa. The proposed models constantly hold when the symmetry model holds, but the converse is not necessarily true. This study also examines what is necessary for a model, in addition to the proposed models, to satisfy the symmetry model, and gives separations of the symmetry model using the proposed and marginal mean equality models. We apply real data to show the utility of the proposed models. The proposed models provide a better fit than that of the existing models.
本文提出了两种基于有序分数的方形列联表非对称模型。所提出的模型可以应用于所有类别的分数已知或未知的情况。在所提出的模型中,观测值落在第(i, j)个单元格而不是第(j, i)个单元格中的对数赔率与类别i和j对应的有序分数的差成反比。所提出模型的不对称参数可用于推断行变量是否随机大于列变量,反之亦然。当对称模型成立时,所提出的模型总是成立的,但反过来不一定成立。本研究还考察了除了所提出的模型之外,模型满足对称性模型所必需的条件,并使用所提出的模型和边际平均等式模型给出了对称模型的分离。我们用实际数据证明了所提出模型的有效性。所提出的模型比现有模型具有更好的拟合性。
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引用次数: 2
Stability Analysis of a Mathematical Model for the Use of Wolbachia to Stop the Spread of Zika Virus Disease 利用沃尔巴克氏体阻止寨卡病毒传播的数学模型的稳定性分析
Pub Date : 2021-06-01 DOI: 10.2478/bile-2021-0003
M. Anyanwu, G. Mbah
Summary The use of wolbachia-infected mosquitoes to stop the spread of zika virus disease is modeled and analyzed. The model consists of a system of 10 ordinary differential equations which describes the dynamics of the disease in the human population, a wolbachia-free Aedes aegypti population, and a wolbachia-infected Aedes aegypti population used for disease control. A stability analysis of the disease-free equilibrium is conducted, which shows that it is both locally and globally asymptotically stable when the reproduction number is less than one. The result of the stability analysis shows that the spread of zika virus disease can be stopped, irrespective of the initial sizes of the infected human and mosquito populations, when wolbachia-infected Aedes aegypti are introduced in the area where the disease is endemic.
利用感染沃尔巴克氏体的蚊子来阻止寨卡病毒病的传播进行了建模和分析。该模型由一个由10个常微分方程组成的系统组成,该系统描述了该疾病在人群、无沃尔巴克氏体的埃及伊蚊种群和用于疾病控制的感染沃尔巴克氏体的埃及伊蚊种群中的动态。对无病平衡点进行了稳定性分析,表明当繁殖数小于1时,无病平衡点是局部和全局渐近稳定的。稳定性分析的结果表明,当将感染沃尔巴克氏体的埃及伊蚊引入寨卡病毒流行地区时,可以阻止寨卡病毒病的传播,而不管受感染的人和蚊子种群的初始规模有多大。
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引用次数: 0
An anti-sum-symmetry model and its orthogonal decomposition for ordinal square contingency tables with an application to grip strength test data 序方列联表的反和对称模型及其正交分解及其在握力试验数据中的应用
Pub Date : 2021-06-01 DOI: 10.2478/bile-2021-0004
S. Ando
Summary For the analysis of R × R square contingency tables, we need to estimate an unknown probability distribution with high confidence from obtained observations. For that purpose, we need to perform the analysis using a statistical model that fits the data well and has a simple interpretation. This study proposes two original models that have symmetric and asymmetric structures between the probability with which the sum of row and column variables is t, for t = 2, . . ., R, and the probability with which the sum of row and column variables is 2(R + 1) − t. The study also reveals that it is necessary to satisfy the anti-global symmetry model, in addition to the proposed asymmetry model, in order to satisfy the proposed symmetry model. This decomposition theorem is useful to explain why the proposed symmetry model does not hold. Moreover, we show that the value of the likelihood ratio chi-squared statistic of the proposed symmetry model is equal to the sum of those of the decomposed models. We evaluate the utility of the proposed models by applying them to real-world grip strength data.
对于R × R平方列联表的分析,我们需要从得到的观测值中估计一个未知的高置信度的概率分布。为此,我们需要使用一个统计模型来执行分析,该模型可以很好地拟合数据并具有简单的解释。本研究提出两个原始模型之间的对称和非对称结构的概率之和的行和列变量t, t = 2,…,R,和概率的总和行和列变量是2 (R + 1)−t。研究还表明,它是必要的,以满足全球对称模型,除了提出不对称模型,为了满足提出的对称模型。这个分解定理有助于解释为什么所提出的对称模型不成立。此外,我们证明了所提出的对称模型的似然比卡方统计量的值等于分解模型的似然比卡方统计量的和。我们通过将所提出的模型应用于实际握力数据来评估其效用。
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引用次数: 1
Properties of an MLE algorithm for the multivariate linear model with a separable covariance matrix structure 具有可分离协方差矩阵结构的多元线性模型的最大似然算法的性质
Pub Date : 2021-06-01 DOI: 10.2478/bile-2021-0005
A. Szczepańska-Álvarez, B. Zawieja, Adolfo Álvarez
Summary In this paper we present properties of an algorithm to determine the maximum likelihood estimators of the covariance matrix when two processes jointly affect the observations. Additionally, one process is partially modeled by a compound symmetry structure. We perform a simulation study of the properties of an iteratively determined estimator of the covariance matrix.
本文给出了当两个过程共同影响观测值时确定协方差矩阵最大似然估计的算法的性质。另外,其中一个过程部分由复合对称结构建模。我们对协方差矩阵的迭代确定估计量的性质进行了模拟研究。
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引用次数: 0
Measure of departure from average marginal homogeneity for the analysis of collapsed ordinal square contingency tables 倒序方列联表分析中偏离平均边际均匀性的测度
Pub Date : 2021-06-01 DOI: 10.2478/bile-2021-0006
Manabu Aizawa, K. Yamamoto, S. Tomizawa
Summary In clinical research, collected data are often classified into ordered categories using a set threshold to evaluate efficacy and safety of treatment. Data can be summarized as a shift table, which displays the change in the frequency of subjects across specified categories from the baseline to post-baseline. Although ordered categories are sometimes recombined into three categories, the combined patterns vary. To consider various collapsed patterns comprehensively, this paper proposes a new measure that represents the degree of departure from average marginal homogeneity, and can distinguish between two kinds of marginal inhomogeneity. Additionally, applications of the proposed measure to clinical data are discussed.
在临床研究中,收集到的数据通常被分类成有序的类别,使用一个设定的阈值来评估治疗的有效性和安全性。数据可以总结为一个移位表,它显示了从基线到基线后指定类别的受试者频率的变化。虽然有序的类别有时会重新组合成三个类别,但组合后的模式各不相同。为了综合考虑各种崩溃模式,本文提出了一种新的度量方法来表示与平均边际均匀性的偏离程度,并能区分两种边际不均匀性。此外,还讨论了该方法在临床数据中的应用。
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引用次数: 1
Defining the effective deformation of the vertebral column 确定脊柱的有效变形
Pub Date : 2020-12-01 DOI: 10.2478/bile-2020-0010
A. Daghighi, H. Tropp
Summary The Cobb angle is calculated in the coronal plane, irrespective of vertebral rotation, lordokyphosis and local wedge properties of individual verte-brae other than the end plates used for the measurement. Rigorous three-dimensional generalizations of the Cobb angle are complicated for at least two reasons. Firstly, the vertebral column is segmented, not continuous, making the choice of rigorous model ambiguous. Secondly, there exists an inherent curvature (in terms of thoracic kyphosis and lumbar lordosis) that may be considered physiologically healthy or ’normal’. When attempting to find a three-dimensional deviation measure, such normal sagittal curvature must be compensated for. In this paper we introduce a three-dimensional local deformation parameter (which we call the local effective deformation) motivated by both biomechanics and the basic theory of spatial curves, and simultaneously introduce a technical procedure to estimate the parameter from CT scans using MPR (multi-phase reconstruction) in PACS (IDS-7). A detailed description of the proposed modelling of vertebral column deformation is given, together with a stepwise procedure to estimate the three-dimensional deformation (in terms of local effective deformation). As a deformation measure it requires knowledge about the natural healthy kypholordosis. A method is described by which such knowledge may be incorporated in future work.
Cobb角是在冠状面上计算的,不考虑椎体旋转、脊柱前凸和单个椎骨的局部楔形特性,而不是用于测量的端板。Cobb角的严格的三维推广是复杂的,至少有两个原因。首先,脊柱是分段的,不是连续的,使得严格模型的选择不明确。其次,存在固有的弯曲(就胸后凸和腰椎前凸而言),这可能被认为是生理上健康或“正常”的。当试图找到一个三维偏差测量,这样的正常矢状曲率必须补偿。本文介绍了基于生物力学和空间曲线基本理论的三维局部变形参数(我们称之为局部有效变形),同时介绍了在PACS (IDS-7)中利用MPR(多相重建)从CT扫描中估计该参数的技术步骤。给出了所提出的脊柱变形建模的详细描述,以及估计三维变形的逐步过程(根据局部有效变形)。作为一种变形测量,它需要了解自然健康的脊柱后凸。本文描述了一种方法,通过这种方法,这些知识可能会被纳入未来的工作中。
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引用次数: 0
期刊
Biometrical Letters
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