Pub Date : 2016-04-20DOI: 10.4172/2169-0111.1000154
Sarra Nasr Mahmoud, A. Abuaffan
Background: Malocclusion plays an important role on the overall health of individuals, careful attention to malocclusion in individuals with special needs leads to a considerable improvement in the quality of their life. Aim: To determine the prevalence of malocclusion and the orthodontic treatment need among Down’s syndrome, deafness and cerebral palsy individuals in Khartoum state, and compare the results with normal individuals of the same age group. Methods: All individuals with special needs were examined for determination of malocclusion and need for treatment, and compared with matching number and age of normal individuals. Results: Crowding and Class III Angle’s were found to be the highest malocclusion in Down’s syndrome individuals, whereas Class II over jet and over bite were found to be the most prevalent malocclusions in individuals with cerebral palsy. Deaf individuals were at most need for orthodontic treatment (47.8%). Conclusion: Sudanese with special needs have high prevalence of malocclusion and are of more need for orthodontic treatment than normal individuals.
{"title":"Sudanese Individuals with Special Need","authors":"Sarra Nasr Mahmoud, A. Abuaffan","doi":"10.4172/2169-0111.1000154","DOIUrl":"https://doi.org/10.4172/2169-0111.1000154","url":null,"abstract":"Background: Malocclusion plays an important role on the overall health of individuals, careful attention to malocclusion in individuals with special needs leads to a considerable improvement in the quality of their life. Aim: To determine the prevalence of malocclusion and the orthodontic treatment need among Down’s syndrome, deafness and cerebral palsy individuals in Khartoum state, and compare the results with normal individuals of the same age group. Methods: All individuals with special needs were examined for determination of malocclusion and need for treatment, and compared with matching number and age of normal individuals. Results: Crowding and Class III Angle’s were found to be the highest malocclusion in Down’s syndrome individuals, whereas Class II over jet and over bite were found to be the most prevalent malocclusions in individuals with cerebral palsy. Deaf individuals were at most need for orthodontic treatment (47.8%). Conclusion: Sudanese with special needs have high prevalence of malocclusion and are of more need for orthodontic treatment than normal individuals.","PeriodicalId":89733,"journal":{"name":"Advancements in genetic engineering","volume":"5 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2016-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2169-0111.1000154","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70877502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-04-16DOI: 10.4172/2169-0111.1000153
Hiba S. Abduljalil, A. Abuaffan
Introduction: Mother’s dental health knowledge has a vital role on children's dental health. This study aimed to assess knowledge and practice of mothers in relation to dental health of pre-school children. Subjects and methods: A cross-sectional pre-school based study of 419 mothers of 3-5 years old pre-school children were selected randomly from 20 kindergartens in Khartoum North, Sudan. An interviewer administered questionnaire used to assess the mother’s dental health knowledge and practice in relation to mother’s age, education and occupation. Results: The majority of mothers 394 (94%) age were 20 to 40 years old, 52.7% had university education and 63.7% were housewives. In general, mothers showed good knowledge, the overall mean ± SD knowledge score was 7.22 ± 1.42, while for practice the overall mean ± SD practice score was 41.3 ± 11.8. Significant association found between dental health knowledge and practice and mother’s education level (p = 0.00). Conclusion: Relatively good mother knowledge regarding dental health of preschool children but regrettably this knowledge was not fully reflected on practices. Higher education mothers had better knowledge and practices. The findings of this study emphasize the significant role of mothers in promoting dental health of pre-school children.
{"title":"Knowledge and Practice of Mothers in Relation to Dental Health of Pre- School Children","authors":"Hiba S. Abduljalil, A. Abuaffan","doi":"10.4172/2169-0111.1000153","DOIUrl":"https://doi.org/10.4172/2169-0111.1000153","url":null,"abstract":"Introduction: Mother’s dental health knowledge has a vital role on children's dental health. This study aimed to assess knowledge and practice of mothers in relation to dental health of pre-school children. \u0000Subjects and methods: A cross-sectional pre-school based study of 419 mothers of 3-5 years old pre-school children were selected randomly from 20 kindergartens in Khartoum North, Sudan. An interviewer administered questionnaire used to assess the mother’s dental health knowledge and practice in relation to mother’s age, education and occupation. \u0000Results: The majority of mothers 394 (94%) age were 20 to 40 years old, 52.7% had university education and 63.7% were housewives. In general, mothers showed good knowledge, the overall mean ± SD knowledge score was 7.22 ± 1.42, while for practice the overall mean ± SD practice score was 41.3 ± 11.8. Significant association found between dental health knowledge and practice and mother’s education level (p = 0.00). \u0000Conclusion: Relatively good mother knowledge regarding dental health of preschool children but regrettably this knowledge was not fully reflected on practices. Higher education mothers had better knowledge and practices. The findings of this study emphasize the significant role of mothers in promoting dental health of pre-school children.","PeriodicalId":89733,"journal":{"name":"Advancements in genetic engineering","volume":"5 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2016-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2169-0111.1000153","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70876984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-03-28DOI: 10.4172/2169-0111.1000151
Amin Saleh Halum, M. M. Bhinder
In today's day and age, technology is constantly evolving, rendering other forms of technology once considered state-of-the-art to become obsolete. These technological innovations which are occurring affect nearly every, and all fields of medicine. These trending innovations can be seen in the field of genetics as well where Geneticists are able to identify an individual's risks of transmitting a genetic disorder on to the next generation, through their offspring. This non-directive branch of genetics, known as genetic counselling goes hand-in-hand with two other branches of genetics to allow the counsellor to identify certain genetic abnormalities and also provide hope to the patient that there is the possibility of having a normal child. One such branch is known as pharmacogenetics, a field of genetics that is advancing rapidly, and still has much allure and mystique to it. Its main aim is to make a significant impact, clinically, on the lives of patients it is employed to treat. It is a field that has quite a bit of potential to affect a large number of different groups within the healthcare field that ranges from pharmacists and physicians to pharmaceutical and insurance companies. Gene therapy is the other branch involved, and it has to do with the insertion of genes into the cells and tissues of an individual in order to treat a specific pathosis present. At the current time, both are new fields but with the commonplace innovations in technology occurring around us, it is not long before these two techniques will fulfil the hopes and aspirations of many people.
{"title":"Genetic Counselling, Pharmacogenetics and Gene Therapy: The Paving-Stones Leading to Brighter Futures","authors":"Amin Saleh Halum, M. M. Bhinder","doi":"10.4172/2169-0111.1000151","DOIUrl":"https://doi.org/10.4172/2169-0111.1000151","url":null,"abstract":"In today's day and age, technology is constantly evolving, rendering other forms of technology once considered state-of-the-art to become obsolete. These technological innovations which are occurring affect nearly every, and all fields of medicine. These trending innovations can be seen in the field of genetics as well where Geneticists are able to identify an individual's risks of transmitting a genetic disorder on to the next generation, through their offspring. This non-directive branch of genetics, known as genetic counselling goes hand-in-hand with two other branches of genetics to allow the counsellor to identify certain genetic abnormalities and also provide hope to the patient that there is the possibility of having a normal child. One such branch is known as pharmacogenetics, a field of genetics that is advancing rapidly, and still has much allure and mystique to it. Its main aim is to make a significant impact, clinically, on the lives of patients it is employed to treat. It is a field that has quite a bit of potential to affect a large number of different groups within the healthcare field that ranges from pharmacists and physicians to pharmaceutical and insurance companies. Gene therapy is the other branch involved, and it has to do with the insertion of genes into the cells and tissues of an individual in order to treat a specific pathosis present. At the current time, both are new fields but with the commonplace innovations in technology occurring around us, it is not long before these two techniques will fulfil the hopes and aspirations of many people.","PeriodicalId":89733,"journal":{"name":"Advancements in genetic engineering","volume":"2016 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2016-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70876700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-03-28DOI: 10.4172/2169-0111.1000150
A. Nikkhah
This editorial concisely describes a critical pragmatic insight into omics technologies and gene/cell engineering fields. Omical biotechnologies have emerged as potentially useful tools to explore cell properties and help pragmatically engineer a variety of cells. The omical technologies have enabled breaking cell characteristics into various biochemical, genomic, metabolomic and proteomic components. Such information may be descriptive and be utilized to hasten cell science expansion. However, the secret of taking the real advantage from such omical information lies in the development of practical perspectives that simulate real life scenarios to help tackle the health problems often encountered by the modern man.
{"title":"A Critique of Functional Genomic Tools","authors":"A. Nikkhah","doi":"10.4172/2169-0111.1000150","DOIUrl":"https://doi.org/10.4172/2169-0111.1000150","url":null,"abstract":"This editorial concisely describes a critical pragmatic insight into omics technologies and gene/cell engineering fields. Omical biotechnologies have emerged as potentially useful tools to explore cell properties and help pragmatically engineer a variety of cells. The omical technologies have enabled breaking cell characteristics into various biochemical, genomic, metabolomic and proteomic components. Such information may be descriptive and be utilized to hasten cell science expansion. However, the secret of taking the real advantage from such omical information lies in the development of practical perspectives that simulate real life scenarios to help tackle the health problems often encountered by the modern man.","PeriodicalId":89733,"journal":{"name":"Advancements in genetic engineering","volume":"5 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2016-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70876604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-03-28DOI: 10.4172/2169-0111.1000149
Debraj Biswal
Understanding the life cycle and pathogenesis of zoonotic helminths is extremely important because a majority of the infections are acquired from the livestock animals. These animals (including birds) live in close association with the human beings and serve as a reservoir of infections [1]. Taenia solium cysticercosis is currently reported as an important re-emerging zoonosis and the development of sensitive and specific diagnostic tests are needed urgently.
{"title":"Molecular methods for diagnosis of Zoonotic Helminths: Can they be made accessible to the common Man?","authors":"Debraj Biswal","doi":"10.4172/2169-0111.1000149","DOIUrl":"https://doi.org/10.4172/2169-0111.1000149","url":null,"abstract":"Understanding the life cycle and pathogenesis of zoonotic helminths is extremely important because a majority of the infections are acquired from the livestock animals. These animals (including birds) live in close association with the human beings and serve as a reservoir of infections [1]. Taenia solium cysticercosis is currently reported as an important re-emerging zoonosis and the development of sensitive and specific diagnostic tests are needed urgently.","PeriodicalId":89733,"journal":{"name":"Advancements in genetic engineering","volume":"5 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2016-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70876961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-03-22DOI: 10.4172/2169-0111.1000148
Gwaza Ds, N. Dim, O. Momoh
The study was carried out at Akpehe poultry farm, Makurdi.540 chicks produced from matings of 80 dams and 8 sires each of the Fulani and the Tiv local chickens ecotypes were used for the study. Sire, ecotype and dam had significant effect on age at first egg and body weight at first egg. Heritability estimates of age at first egg, body weight at first egg and egg weight due to sire variance component were high. There were significant positive genetic correlation between age at first egg, body weight at first egg and egg weight. Egg weight also had significant positive genetic correlation with egg length and egg diameter. Direct selection can be apply to age at first egg, body weight at first egg and egg weight in a multiple traits selection program to improve egg production traits. Indirect selection can also be apply to age at first egg and body weight at first egg in a multiple traits selection to exploit the correlated response to egg weight, egg diameter and egg length.
{"title":"Genetic improvement of egg production traits by direct and indirect selection of egg traits in Nigerian local chickens","authors":"Gwaza Ds, N. Dim, O. Momoh","doi":"10.4172/2169-0111.1000148","DOIUrl":"https://doi.org/10.4172/2169-0111.1000148","url":null,"abstract":"The study was carried out at Akpehe poultry farm, Makurdi.540 chicks produced from matings of 80 dams and 8 sires each of the Fulani and the Tiv local chickens ecotypes were used for the study. Sire, ecotype and dam had significant effect on age at first egg and body weight at first egg. Heritability estimates of age at first egg, body weight at first egg and egg weight due to sire variance component were high. There were significant positive genetic correlation between age at first egg, body weight at first egg and egg weight. Egg weight also had significant positive genetic correlation with egg length and egg diameter. Direct selection can be apply to age at first egg, body weight at first egg and egg weight in a multiple traits selection program to improve egg production traits. Indirect selection can also be apply to age at first egg and body weight at first egg in a multiple traits selection to exploit the correlated response to egg weight, egg diameter and egg length.","PeriodicalId":89733,"journal":{"name":"Advancements in genetic engineering","volume":"5 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2016-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70876941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-03-20DOI: 10.4172/2169-0111.1000147
Gwaza Ds, N. Dim, O. Momoh
The study was conducted at Akpehe poultry farm Makurdi. About 50 adult females and 10 males each of the Fulani and the Tiv ecotypes were used for the study. The birds were house singly in identified pens partitioned into smaller units and hand-mated in the pen. About 600 fertile eggs were used to study the effect of sire and dam on fertility, embryonic mortality and hatchability. The eggs were incubated in different batches. Candling was carried on the 7th and 14th days to remove infertile eggs and those with dead embryos. Sire and dam had significant effect on fertility, embryonic mortality and hatchability. The effect of the dam was due to the variation in non-additive and additive genetic variances in the dam that influences its egg environment, nutrients sufficiency and delivery systems and other maternal effects that support fertility, embryo survival and hatchability, and that which affect maternal effects, egg environment and nutrients delivery systems that do not support fertility, embryo survival and hatchability due to genetic variation. The effect of the sire was due to additive genetic variance of the sire determining fertility, embryo survival and hatchability due to proper transcription and translation of genetic information. Or the additive genetic variance of the sire that determines the frequency of deleterious and lethal genes that had transition that supported improper transcription and translation of genetic information due to chromosomal aberration. Selecting superior sires and dams from the population base on high fertility, embryo survival and hatchability in a multiple traits selection may lead genetic improvement of these traits.
{"title":"Evaluation of Sire and Dam for Genetic Improvement of Fertility, Embryonic Mortality and Hatchability in Nigerian Local Chickens Populations","authors":"Gwaza Ds, N. Dim, O. Momoh","doi":"10.4172/2169-0111.1000147","DOIUrl":"https://doi.org/10.4172/2169-0111.1000147","url":null,"abstract":"The study was conducted at Akpehe poultry farm Makurdi. About 50 adult females and 10 males each of the Fulani and the Tiv ecotypes were used for the study. The birds were house singly in identified pens partitioned into smaller units and hand-mated in the pen. About 600 fertile eggs were used to study the effect of sire and dam on fertility, embryonic mortality and hatchability. The eggs were incubated in different batches. Candling was carried on the 7th and 14th days to remove infertile eggs and those with dead embryos. Sire and dam had significant effect on fertility, embryonic mortality and hatchability. The effect of the dam was due to the variation in non-additive and additive genetic variances in the dam that influences its egg environment, nutrients sufficiency and delivery systems and other maternal effects that support fertility, embryo survival and hatchability, and that which affect maternal effects, egg environment and nutrients delivery systems that do not support fertility, embryo survival and hatchability due to genetic variation. The effect of the sire was due to additive genetic variance of the sire determining fertility, embryo survival and hatchability due to proper transcription and translation of genetic information. Or the additive genetic variance of the sire that determines the frequency of deleterious and lethal genes that had transition that supported improper transcription and translation of genetic information due to chromosomal aberration. Selecting superior sires and dams from the population base on high fertility, embryo survival and hatchability in a multiple traits selection may lead genetic improvement of these traits.","PeriodicalId":89733,"journal":{"name":"Advancements in genetic engineering","volume":"5 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2016-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70877015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-03-10DOI: 10.4172/2169-0111.1000146
Rimi Paul, Bhau Bs, K. Zaman, H. Sharma
Turmeric has been used as condiments and as medicine by traditional healers of northeast India. The rhizome contains various constituents including polyphenols, polysaccharides and alkaloids. A simple method was adapted for isolation, PCR amplification of DNA and the RAPD analysis was carried out. The results of the study are reported here.
{"title":"RAPD Analysis of DNA Isolated from Turmeric Rhizomes Collected from Northeast India","authors":"Rimi Paul, Bhau Bs, K. Zaman, H. Sharma","doi":"10.4172/2169-0111.1000146","DOIUrl":"https://doi.org/10.4172/2169-0111.1000146","url":null,"abstract":"Turmeric has been used as condiments and as medicine by traditional healers of northeast India. The rhizome contains various constituents including polyphenols, polysaccharides and alkaloids. A simple method was adapted for isolation, PCR amplification of DNA and the RAPD analysis was carried out. The results of the study are reported here.","PeriodicalId":89733,"journal":{"name":"Advancements in genetic engineering","volume":"2016 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2016-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70876990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-03-06DOI: 10.4172/2169-0111.1000145
M. H. Shirazi, S. Hosseini
Stroke is the second cause of mortality in industrial countries after ischemic heart disease. Ischemic stroke results from an artery occlusion and leads to oxygen and glucose shortage in brain. Cerebral ischemia results in inflammation and oxidative stress leading to neuronal loss and brain damage. To these days, rt-PA is the only approved drug for stroke; however, increasing the risk of bleeding and golden time limitation are the problems associated with rt-PA.
{"title":"Optimized Protocol is the Key for Clinical Use of Stem Cell Therapy in Stroke","authors":"M. H. Shirazi, S. Hosseini","doi":"10.4172/2169-0111.1000145","DOIUrl":"https://doi.org/10.4172/2169-0111.1000145","url":null,"abstract":"Stroke is the second cause of mortality in industrial countries after ischemic heart disease. Ischemic stroke results from an artery occlusion and leads to oxygen and glucose shortage in brain. Cerebral ischemia results in inflammation and oxidative stress leading to neuronal loss and brain damage. To these days, rt-PA is the only approved drug for stroke; however, increasing the risk of bleeding and golden time limitation are the problems associated with rt-PA.","PeriodicalId":89733,"journal":{"name":"Advancements in genetic engineering","volume":"2016 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2016-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2169-0111.1000145","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70876744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-02-29DOI: 10.4172/2169-0111.1000E115
T. Attia, M. Saeed
More than 30 years ago when I started my clinical practice, we did not manage only the diseases, but sometimes we have to treat side effects of available medicine. Pork insulin was the insulin available to treat type1 diabetes, and antibodies to insulin were a big problem to the patients.
{"title":"Genetic Engineering: A Hope for Tomorrow","authors":"T. Attia, M. Saeed","doi":"10.4172/2169-0111.1000E115","DOIUrl":"https://doi.org/10.4172/2169-0111.1000E115","url":null,"abstract":"More than 30 years ago when I started my clinical practice, we did not manage only the diseases, but sometimes we have to treat side effects of available medicine. Pork insulin was the insulin available to treat type1 diabetes, and antibodies to insulin were a big problem to the patients.","PeriodicalId":89733,"journal":{"name":"Advancements in genetic engineering","volume":"2016 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2016-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70877612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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