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The development of an in vitro glenohumeral testing rig 体外盂肱骨试验装置的研制
Pub Date : 2012-10-16 DOI: 10.1504/IJECB.2012.049808
D. Hughes
Until recently the accurate measurement of contact loads acting in the glenohumeral joint have been difficult to calculate and define. Now, contact forces and moments are measured in vivo using telemeterised shoulder implants. This method limits testing opportunities so a dynamic shoulder testing apparatus has been developed to examine glenohumeral joint motion and forces. This in vitro study evaluated the accuracy of forces generated in the glenohumeral joint using an instrumented prosthetic implant. Forces were applied to cables to simulate loading of the supraspinatus, subscapularis, infraspinatus/teres minor, long head biceps and anterior, middle, and posterior deltoid muscles. The test rig reproduces the 6DoF of the glenohumeral joint and accurately recreates the contact forces measured in vivo. This test rig will allow many more tests to be simulated including comparison of fixation methods and high impact injuries.
直到最近,准确测量作用于盂肱关节的接触载荷一直难以计算和定义。现在,接触力和力矩是使用远程测量肩部植入物在体内测量的。这种方法限制了测试机会,因此开发了一种动态肩部测试设备来检查肩关节运动和力。这项体外研究评估了使用固定式假体植入物在盂肱关节产生的力的准确性。对缆绳施加力以模拟冈上肌、肩胛下肌、冈下肌/小圆肌、长头二头肌和前、中、后三角肌的负荷。该试验台再现了关节的6DoF,准确再现了体内测量的接触力。该测试平台将允许模拟更多的测试,包括固定方法和高冲击损伤的比较。
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引用次数: 1
A novel device for detection of soft tissue inflammation: dynamic behaviour of a functionally graded AFM cantilever 一种用于检测软组织炎症的新装置:功能分级AFM悬臂的动态行为
Pub Date : 2012-10-16 DOI: 10.1504/IJECB.2012.049803
K. Firoozbakhsh, M. Ahmadian, M. Rahaeifard, M. Kahrobaiyan
Atomic force microscopes (AFM) are devices used for surface roughness detection. A novel AFM device composed of a tip attached to a cantilever beam is proposed for precise soft-tissue-inflammation detection. It is assumed that the beam is made of functionally graded materials (FGMs) with properties varying throughout the thickness. Two low resonant frequencies and the sensitivities of the AFM cantilever are studied. A relationship is developed to evaluate the sensitivity of a FGM micro-cantilever beam. The effects of mass distributions of material constituents, surface contact stiffness, and geometric parameters on the resonant frequencies and sensitivities are studied. The high sensitivity of such device to the stiffness of the contact surface is proposed to be the recognition key for soft tissue inflammation.
原子力显微镜(AFM)是一种用于表面粗糙度检测的仪器。提出了一种新型的由附着在悬臂梁上的尖端组成的AFM装置,用于软组织炎症的精确检测。假设梁由功能梯度材料(fgm)制成,其性能在整个厚度范围内变化。研究了AFM悬臂梁的两种低谐振频率和灵敏度。建立了一个关系式来评价FGM微悬臂梁的灵敏度。研究了材料成分的质量分布、表面接触刚度和几何参数对谐振频率和灵敏度的影响。该装置对接触面刚度的高灵敏度被认为是软组织炎症的识别关键。
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引用次数: 1
An atomistic investigation into the molecular effects of osteogenesis imperfecta like genetic mutations on biomaterial strength 成骨不全如基因突变对生物材料强度的分子效应的原子性研究
Pub Date : 2012-10-16 DOI: 10.1504/IJECB.2012.049802
D. K. Dubey, V. Tomar
Osteogenesis imperfecta (OI) is a genetic disease marked by extreme bone fragility and is associated with mutations in tropocollagen (TC) molecule and changes in hydroxyapatite (HAP) mineral texture. Mutations in TC can manifest in both ways, substitution of polypeptide chains and point mutations of residues. This study presents a mechanistic view on the effects of OI mutations in TC on strength of model TC-HAP biomaterials with two different mineral distributions using three dimensional atomistic simulations. Analysis points out that substitution of residue sequences with higher number of side chain functional groups impart higher strength to the TC-HAP biomaterials. Results show that the effect of TC point mutations on the strength of TC-HAP biomaterials is insignificant. Instead, change in mineral distribution showed significant impact on the overall strength of TC-HAP biomaterials. Overall, study suggests that TC mutations manifest themselves by altering the mineral distribution during hydroxyapatite ...
成骨不全症(Osteogenesis imperfecta, OI)是一种以骨骼极度脆弱为特征的遗传性疾病,与胶原蛋白(tropocollagen, TC)分子突变和羟基磷灰石(hydroxyapatite, HAP)矿物结构改变有关。TC的突变可以表现为多肽链的取代和残基的点突变两种方式。本研究利用三维原子模拟的方法,从机制角度探讨了TC中OI突变对两种不同矿物分布的TC- hap模型生物材料强度的影响。分析表明,侧链官能团数量较多的残基序列被取代,使TC-HAP生物材料具有更高的强度。结果表明,TC点突变对TC- hap生物材料强度的影响不显著。相反,矿物分布的变化对TC-HAP生物材料的整体强度有显著影响。总的来说,研究表明TC突变通过改变羟基磷灰石生长过程中矿物分布来表现。
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引用次数: 0
A comparison between inverse dynamics skeletal and muscular models 逆动力学骨骼和肌肉模型的比较
Pub Date : 2012-10-16 DOI: 10.1504/IJECB.2012.049807
S. Mari, E. Pennestrì, Martina Trebbi, F. Nappi, D. Rughi
This investigation has the purpose of developing and cross-validating algorithms and software tools for quantitative ergonomic analyses of workers movements. In particular, the results from a skeletal inverse dynamics model are directly compared with those obtained from a muscular model herein proposed. Both models rely upon experimentally gathered kinematic and electromyography data. The 2D skeletal model is based on a multibody dynamics formulation. The software implementation can perform both kinematic and inverse dynamic analyses. Kinematic input data required by the model have been collected using an optoelectronic human motion capture system. The kinematics of the model has been compared with experimentally collected data. The muscular electromyography (EMG)-assisted model discussed is particularly suitable for biarticular muscles. Joint torques, muscular forces and powers can be also estimated. The inputs required by this model have been collected recording surface electromyographic signals and using some kinematic output from the skeletal model. The results from mathematical models have been compared for cross-validation, and their adequacy for ergonomy analyses assessed.
这项调查的目的是开发和交叉验证算法和软件工具,用于工人运动的定量人体工程学分析。特别地,骨骼逆动力学模型的结果直接与本文提出的肌肉模型的结果进行了比较。这两种模型都依赖于实验收集的运动学和肌电图数据。二维骨骼模型基于多体动力学公式。软件实现可以进行运动学和逆动力学分析。利用光电人体运动捕捉系统收集了模型所需的运动学输入数据。模型的运动学与实验数据进行了比较。所讨论的肌肉肌电图(EMG)辅助模型特别适用于双关节肌肉。关节扭矩,肌肉力量和功率也可以估计。该模型所需的输入已被收集,记录表面肌电图信号并使用骨骼模型的一些运动学输出。数学模型的结果进行了交叉验证的比较,并评估了其对人体工程学分析的充分性。
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引用次数: 0
Simulation study of the importance of biarticular muscles on human vertical jump performance 双关节肌肉对人体垂直跳跃性能重要性的模拟研究
Pub Date : 2011-05-09 DOI: 10.1504/IJECB.2011.039945
P. Prokopow, K. Pomorski
The aim of this study was to quantify the importance of biarticular muscles on vertical squat jump. In order to do that, we used a neuromusculoskeletal model and a forward dynamics computer simulation. In separate trials biarticular muscles were removed from the neuromusculoskeletal model, firstly only one muscle was removed each trial, and then all three biarticular muscles were removed together in one more trial. Investigated were three main groups of biarticular muscles of lower extremities: m. rectus femoris, hamstrings and m. gastrocemius. The results demonstrated that monoarticular muscles are primary producers of the force used to accelerate the body’s centre of gravity vertically. While the function of biarticular muscles is twofold: Therefore, we conclude that the most important function of biarticular muscles in a vertical jump is to help to coordinate jump movement and increase the effectiveness of the usage of muscle force to accelerate vertically the body’s centre of gravity.
本研究的目的是量化双关节肌肉在垂直深蹲跳中的重要性。为了做到这一点,我们使用了神经肌肉骨骼模型和前向动力学计算机模拟。在单独的试验中,从神经肌肉骨骼模型中去除双关节肌肉,首先每次试验只去除一块肌肉,然后在另一次试验中同时去除所有三块双关节肌肉。研究了三组主要的下肢双关节肌:股直肌、腘绳肌和腓肠肌。结果表明,单关节肌肉是用来加速身体垂直重心的力的主要生产者。而双关节肌肉的功能是双重的:因此,我们得出结论,双关节肌肉在垂直跳跃中最重要的功能是帮助协调跳跃运动,提高肌肉力量的使用效率,以加速身体的垂直重心。
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引用次数: 2
Effect of vacuum mixer brand on tensile properties of acrylic bone cement 真空混合机牌号对丙烯酸骨水泥拉伸性能的影响
Pub Date : 2011-05-09 DOI: 10.1504/IJECB.2011.039948
A. Schonning, Carmen Masnita Iusan, M. Rawls, M. Straatsma, P. Wludyka, M. Patney, J. R. Cotton
The effect of vacuum mixer brand is studied on six commercial bone cements, three with prophylactic doses of antibiotics and three without. The modulus of elasticity, ultimate tensile strength, maximum strain, and 0.2% yield strength was analysed. Bone cement specimens were manufactured and tested in accordance with ASTM D638 specifications using three different types of vacuum mixers in an operating room. The specimens were tested in a universal testing machine. Statistical analysis revealed that a proprietary mixer did not generally outperform the other two mixers for its own cement. It was found that the mixer had a significant effect on the results and that the Stryker/Simplex mixer generally outperformed Biomet and Zimmer. However, for the Simplex bone cement, the mixer type did not have a significant effect for most of the data analysed. The overall conclusion is that the proprietary mixer does not perform the best with its own cement.
研究了真空混合器品牌对6种市售骨水泥的影响,其中3种有预防性抗生素剂量,3种没有。分析了弹性模量、极限抗拉强度、最大应变和0.2%屈服强度。骨水泥标本按照ASTM D638规范在手术室使用三种不同类型的真空混合器制作和测试。试样在万能试验机上进行了试验。统计分析表明,一个专有的搅拌器通常不优于其他两个搅拌器为自己的水泥。我们发现混合器对结果有显著的影响,Stryker/Simplex混合器通常优于Biomet和Zimmer。然而,对于单纯形骨水泥,混合器类型对大多数分析数据没有显著影响。总的结论是,专有搅拌机与自己的水泥表现不佳。
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引用次数: 0
A review of motion estimation methods for non-invasive ultrasound motion and emerging strain imaging methods of carotid artery plaques 非侵入性超声运动估计方法及新兴的颈动脉斑块应变成像方法综述
Pub Date : 2011-05-09 DOI: 10.1504/IJECB.2011.039947
S. Murillo, M. Pattichis, E. Barriga
Non-invasive ultrasound imaging of carotid plaques is used in routine clinical evaluation of atherosclerosis and stroke. Strain imaging of the atherosclerotic plaques represents a very promising, emerging application of ultrasound imaging because it can assess plaque vulnerability without the risks of intervention. The promise of strain imaging includes the development of advanced diagnostic tools that can be used to predict plaque rupture. This review paper presents the fundamental assumptions and methods that can be used to extract motion estimates from ultrasound images. In terms of assumptions, both the constant and non-constant brightness models are presented. The most commonly used energy functionals are presented, along with both local and global solutions. Motion and strain imaging examples are also provided to demonstrate the methods. Our goal is that this review will facilitate the development of new, reliable strain imaging methods that can be used to assess the risk of plaque rupture.
颈动脉斑块的无创超声成像用于动脉粥样硬化和脑卒中的常规临床评估。动脉粥样硬化斑块应变成像是一种非常有前途的、新兴的超声成像应用,因为它可以在没有干预风险的情况下评估斑块易损性。应变成像的前景包括可用于预测斑块破裂的先进诊断工具的发展。本文介绍了从超声图像中提取运动估计的基本假设和方法。在假设方面,提出了恒定和非恒定亮度模型。介绍了最常用的能源函数,以及本地和全球解决方案。还提供了运动和应变成像示例来演示该方法。我们的目标是,这篇综述将促进新的,可靠的应变成像方法的发展,可用于评估斑块破裂的风险。
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引用次数: 4
An energy-based technique for the development of a mechanobiological growth model of vertebrae 一种基于能量的技术,用于开发椎骨的机械生物学生长模型
Pub Date : 2011-05-09 DOI: 10.1504/IJECB.2011.039949
Hui Lin, Mei‐qing Wang
Mechanobiological growth is the biological process whereby bone growth is modulated by mechanical loading. The goal of this study is to develop an energy-based mechanobiological bone growth model. Mechanobiological procedures basically include mechanosensing and mechanoregulation. This study represented the mechanosensing as a mathematical model combining energy and mechanical-triggered deformation. The mechanoregulation was modelled as a mathematical form integrated distortion and dilatation energy. Mechanobiological growth model was developed from those two procedures and represented as a function of distortion and dilatation stresses. The model was tested by using finite element model of a thoracic vertebra (T7) for simulating one-year growth procedure under multi-axial loads. The simulation results presented the retarded and stimulated growth under compression and tension. Shear stress increased the growth rate with 20%–40%. This model agreed with experimental study of growth and published numerical growth simulation of human vertebrae as well as mechanobiology theory. This model allows simulating vertebral growth under multi-direction loads.
机械生物学生长是骨生长受机械负荷调节的生物过程。本研究的目的是建立一种基于能量的机械生物学骨生长模型。机械生物学程序基本上包括机械传感和机械调节。本研究将机械传感描述为能量与机械触发变形相结合的数学模型。将力学调节建模为综合变形能和膨胀能的数学形式。力学生物学生长模型是由这两个过程发展起来的,并表示为扭曲和扩张应力的函数。采用胸椎(T7)有限元模型模拟多轴载荷下一年的生长过程,对模型进行了验证。模拟结果表明,在压缩和拉伸作用下,材料的生长受到了抑制和刺激。剪切应力使生长速率提高了20% ~ 40%。该模型与生长的实验研究和发表的人类椎骨的数值生长模拟以及力学生物学理论一致。该模型可以模拟椎骨在多向载荷下的生长。
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引用次数: 0
Evaluation of the rotational stiffness and visco-elasticity of the low back and improving the low back visco-elasticity 评价下背部的转动刚度和粘弹性,提高下背部的粘弹性
Pub Date : 2011-05-09 DOI: 10.1504/IJECB.2011.039950
H. Chaudhry, N. Atalla, V. Singh, Max Roman, T. Findley
An automated anatomical torsion monitor (A-ATM) is developed to evaluate the stiffness and visco-elasticity of the low back as a static load is applied and removed from the pelvis. The resulting hysteresis loop area (HLA) is used to evaluate the mechanical properties of the low back. Also a technique for improving the low back dysfunction by imparting oscillations to the low back is presented. The before and after HLAs are compared for objective evaluation. It is observed that providing oscillations to the low back for five minutes at a frequency of 20 cycles per minute results in improved elasticity of the low back for those subjects whose BMI is 25 or less and an insignificant change in stiffness for all the subjects. However the correct displacement amplitude, frequency, and duration of treatment will depend upon individual medical and physical conditions.
开发了一种自动解剖扭转监测仪(a - atm),用于评估骨盆施加和移除静载荷时下背部的刚度和粘弹性。所得的回滞面积(HLA)用于评估下背部的力学性能。此外,一种技术,以改善下背部功能障碍传授振荡到下背部提出。对hla前后进行比较,客观评价。我们观察到,以每分钟20个周期的频率对下背部进行5分钟的振荡,结果改善了BMI为25或更低的受试者的下背部弹性,并且所有受试者的僵硬度变化微不足道。然而,正确的位移幅度、频率和治疗持续时间取决于个人的医疗和身体状况。
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引用次数: 3
Hip implant stem interfacial motion, a finite element analysis 髋关节假体茎部界面运动,进行有限元分析
Pub Date : 2011-05-09 DOI: 10.1504/IJECB.2011.039946
M. Makola, T. Goswami
A key factor in press fit hip implant fixation is the amount of interfacial motion between implant stem and the femur. A finite element analysis of hip implant stem designs was performed to determine the effect on stem interfacial motion. Implants of distinct cross section and stem profile were analysed. Implant material property effects were studied by analysing cobalt chromium (CoCr), stainless steel (SS316L), and titanium alloy (Ti 6Al-4V) implants. Each implant was subjected to a static loading simulating the weight of an average US male (189 lb) taking a step forward. Study results showed that implant cross section played a role in interfacial motion amounts. Ti 6Al-4V showed the greatest difference in implant interfacial motion as compared to SS316L and CoCr. Continued design and development of implant stems resistant to interfacial motion is needed.
压合式髋关节假体固定的一个关键因素是假体柄与股骨之间的界面运动量。对髋关节假体干设计进行了有限元分析,以确定对干界面运动的影响。对不同横截面和茎廓的种植体进行了分析。通过分析钴铬(CoCr)、不锈钢(SS316L)和钛合金(Ti 6Al-4V)种植体,研究了种植体材料性能的影响。每个植入物都承受着模拟美国男性平均体重(189磅)向前迈一步的静态载荷。研究结果表明,种植体的横截面对界面运动量有影响。与SS316L和CoCr相比,Ti 6Al-4V种植体界面运动差异最大。需要继续设计和开发抗界面运动的种植体茎。
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引用次数: 8
期刊
International journal of experimental and computational biomechanics
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