Background: Extremely low birth weight (ELBW) infants, which weighing less than 1000 g, are at high risk of adverse neonatal outcomes, including intraventricular hemorrhage (IVH), respiratory distress syndrome, and long-term neurodevelopmental impairments. En caul cesarean section (ECCS) is often performed for delivery of ELBW infants to minimize potential damages to the skin, bones, and brain. Although a few studies reported that ECCS is a safe procedure for infants, there is limited research investigating the association between this procedure and neonatal IVH. This study aims to assess whether ECCS contributes to adverse effects during delivery, and association with the occurrence of neonatal IVH.
Methods: We retrospectively examined 252 ELBW infants delivered at our hospital from April 2015 to December 2023. Patients were divided into four groups according to delivery mode: successful ECCS, unsuccessful ECCS, non-trial ECCS, and vaginal delivery. The primary outcome was the incidence of IVH grade ≥ 3 during the neonatal period. The secondary outcomes were hemoglobin level of the infant, umbilical artery blood pH level, and maternal blood loss at delivery.
Results: No significant differences were observed in the median umbilical artery blood pH levels, Hb levels of infants at delivery, the amounts of maternal blood loss at delivery, incidence of IVH grade ≥ 3, intestinal perforation, or neonatal mortality between the group of patients who were attempted en caul cesarean delivery and the group of patients who were not. The incidence of IVH grade ≥ 3 was significantly lower in the group of successful ECCS compared with the other groups (4.8% vs. 15.8%, respectively; p < 0.05). The significant factors for IVH grade ≥ 3 identified on multivariate analysis were gestation week at delivery ≤ 24 weeks (odds ratio [OR] 2.96, 95% confidence interval [CI] 1.33-6.62), steroid administration (OR 0.10, 95% CI 0.01-0.77) and successful ECCS (OR 0.29, 95% CI 0.09-0.87).
Conclusion: ECCS for ELBW infants may reduce the risk of neonatal IVH grade ≥ 3, and does not contribute to anemia and hypoxia of infants at delivery.
背景:极低出生体重(ELBW)婴儿,即体重小于1000 g的婴儿,其不良新生儿结局的风险很高,包括脑室内出血(IVH)、呼吸窘迫综合征和长期神经发育障碍。剖宫产术(ECCS)通常用于分娩低体重婴儿,以尽量减少对皮肤、骨骼和大脑的潜在损害。尽管一些研究报道ECCS是一种安全的婴儿手术,但调查该手术与新生儿IVH之间关系的研究有限。本研究旨在评估ECCS是否会导致分娩期间的不良反应,以及与新生儿IVH发生的关系。方法:回顾性分析2015年4月至2023年12月在我院出生的252例ELBW婴儿。根据分娩方式将患者分为4组:ECCS成功组、ECCS不成功组、非试验性ECCS组和阴道分娩组。主要结局为新生儿期IVH≥3级的发生率。次要结果是婴儿血红蛋白水平、脐带动脉血pH值和产妇分娩时失血。结果:尝试剖宫产组与未尝试剖宫产组在脐带动脉中位血pH值、分娩时婴儿Hb水平、分娩时产妇出血量、IVH≥3级发生率、肠穿孔发生率、新生儿死亡率等方面均无显著差异。ECCS成功组IVH≥3级发生率显著低于其他组(分别为4.8% vs. 15.8%); p结论:ELBW新生儿ECCS可降低新生儿IVH≥3级的风险,且不会导致新生儿分娩时贫血和缺氧。
{"title":"En caul cesarean section for extremely low birth weight infants: a single-center, retrospective study.","authors":"Akira Oku, Syoko Doi, Sorahiro Sunagawa, Aya Yabiku, Akari Kanemura, Nana Yara, Yuko Nakano, Kaoru Yamashita, Chiaki Urasoe, Kaoru Sakumoto, Yutaka Nagai","doi":"10.1186/s12884-025-08607-8","DOIUrl":"https://doi.org/10.1186/s12884-025-08607-8","url":null,"abstract":"<p><strong>Background: </strong>Extremely low birth weight (ELBW) infants, which weighing less than 1000 g, are at high risk of adverse neonatal outcomes, including intraventricular hemorrhage (IVH), respiratory distress syndrome, and long-term neurodevelopmental impairments. En caul cesarean section (ECCS) is often performed for delivery of ELBW infants to minimize potential damages to the skin, bones, and brain. Although a few studies reported that ECCS is a safe procedure for infants, there is limited research investigating the association between this procedure and neonatal IVH. This study aims to assess whether ECCS contributes to adverse effects during delivery, and association with the occurrence of neonatal IVH.</p><p><strong>Methods: </strong>We retrospectively examined 252 ELBW infants delivered at our hospital from April 2015 to December 2023. Patients were divided into four groups according to delivery mode: successful ECCS, unsuccessful ECCS, non-trial ECCS, and vaginal delivery. The primary outcome was the incidence of IVH grade ≥ 3 during the neonatal period. The secondary outcomes were hemoglobin level of the infant, umbilical artery blood pH level, and maternal blood loss at delivery.</p><p><strong>Results: </strong>No significant differences were observed in the median umbilical artery blood pH levels, Hb levels of infants at delivery, the amounts of maternal blood loss at delivery, incidence of IVH grade ≥ 3, intestinal perforation, or neonatal mortality between the group of patients who were attempted en caul cesarean delivery and the group of patients who were not. The incidence of IVH grade ≥ 3 was significantly lower in the group of successful ECCS compared with the other groups (4.8% vs. 15.8%, respectively; p < 0.05). The significant factors for IVH grade ≥ 3 identified on multivariate analysis were gestation week at delivery ≤ 24 weeks (odds ratio [OR] 2.96, 95% confidence interval [CI] 1.33-6.62), steroid administration (OR 0.10, 95% CI 0.01-0.77) and successful ECCS (OR 0.29, 95% CI 0.09-0.87).</p><p><strong>Conclusion: </strong>ECCS for ELBW infants may reduce the risk of neonatal IVH grade ≥ 3, and does not contribute to anemia and hypoxia of infants at delivery.</p>","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145846473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Maternal Endocrine and Metabolic Health and Outcomes (MEMO): a prospective cohort study of gestational diabetes mellitus and subclinical hypothyroidism in China.","authors":"Yuan Zeng, Jie Yu, Yaolin Ren, Jing Ren, Haiyan Chen, Qian Zhang, Xinhua Xiao","doi":"10.1186/s12884-025-08294-5","DOIUrl":"https://doi.org/10.1186/s12884-025-08294-5","url":null,"abstract":"","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145846463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-27DOI: 10.1186/s12884-025-08476-1
Kaat De Backer, Paul Seed, Sam Burton, Elsa Montgomery, Jane Sandall, Abigail Easter
{"title":"Correction: Contact with child protection services during pregnancy: a cross-sectional study using the eLIXIR born in South London, UK maternity-child data linkage.","authors":"Kaat De Backer, Paul Seed, Sam Burton, Elsa Montgomery, Jane Sandall, Abigail Easter","doi":"10.1186/s12884-025-08476-1","DOIUrl":"10.1186/s12884-025-08476-1","url":null,"abstract":"","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":"25 1","pages":"1321"},"PeriodicalIF":2.7,"publicationDate":"2025-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12743399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145846492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Obstetric violence is an emerging health problem in maternal health services utilization. In the study context, there was limited evidence on obstetrics violence. Hence, the aim of this study to assess obstetric violence and its associated factors among HIV-positive women received birth care at public health facilities, Addis Ababa, Ethiopia.
Result: A total of 318 HIV-positive women had been participated in this study yielding 100% response rate. In this study 79% of HIV-positive women reported they had been subjected to at least one form of obstetric violence during birth care. The top three reported forms of obstetric violence: 249 (78.3%) failure to get informed consent, 227 (71.4%) unconsented medical procedure, 140 (44%) neglecting to suffer life-threatening complication. In the multivariable logistic regression analysis were identified that Female birth attendants (AOR = 2.85; 95% CI 1.57, 5.15), less than three times ANC-visitors (AOR = 2.99; 95% CI 1.39, 6.45), age > 35 years old (AOR = 2.47; 95% CI 1.25, 4.90) and primary school attendants (AOR = 2.13; 95% CI 1.08, 4.17) were significantly associated with obstetrics violence. This study identified that high prevalence of obstetric violence among HIV positive women. Hence, mitigation is needed to be undertaken by taking the reported forms of obstetrics violence, socio-demographic and obstetrics variables by ensuring a systematic and strategic intervention for quality birth care utilization through an inclusive involvement like families, communities, government and stakeholders.
背景:产科暴力是孕产妇保健服务利用中的一个新出现的健康问题。在研究背景下,关于产科暴力的证据有限。因此,本研究的目的是评估在埃塞俄比亚亚的斯亚贝巴公共卫生机构接受分娩护理的艾滋病毒阳性妇女的产科暴力及其相关因素。结果:共有318名hiv阳性妇女参与本研究,有效率为100%。在这项研究中,79%的艾滋病毒阳性妇女报告说,她们在分娩护理期间至少遭受过一种形式的产科暴力。报告的前三种形式的产科暴力:249种(78.3%)未获得知情同意,227种(71.4%)未经同意的医疗程序,140种(44%)忽视遭受危及生命的并发症。在多变量logistic回归分析中发现,女性接生员(AOR = 2.85; 95% CI 1.57, 5.15)、少于3次产前检查(AOR = 2.99; 95% CI 1.39, 6.45)、年龄0 - 35岁(AOR = 2.47; 95% CI 1.25, 4.90)和小学接生员(AOR = 2.13; 95% CI 1.08, 4.17)与产科暴力显著相关。这项研究确定了艾滋病毒阳性妇女中产科暴力的高发率。因此,需要通过采取所报告的产科暴力形式、社会人口和产科变量,确保通过家庭、社区、政府和利益攸关方等包容性参与,对优质分娩护理的利用进行系统和战略干预,从而缓解这种情况。
{"title":"Obstetric violence and its associated factors among HIV-positive women receiving birth care at public health facilities, Addis Ababa, Ethiopia.","authors":"Anteneh Wondimagegn Assefa, Basha Ayele, Seteamlak Adane Masersha","doi":"10.1186/s12884-025-08440-z","DOIUrl":"https://doi.org/10.1186/s12884-025-08440-z","url":null,"abstract":"<p><strong>Background: </strong>Obstetric violence is an emerging health problem in maternal health services utilization. In the study context, there was limited evidence on obstetrics violence. Hence, the aim of this study to assess obstetric violence and its associated factors among HIV-positive women received birth care at public health facilities, Addis Ababa, Ethiopia.</p><p><strong>Result: </strong>A total of 318 HIV-positive women had been participated in this study yielding 100% response rate. In this study 79% of HIV-positive women reported they had been subjected to at least one form of obstetric violence during birth care. The top three reported forms of obstetric violence: 249 (78.3%) failure to get informed consent, 227 (71.4%) unconsented medical procedure, 140 (44%) neglecting to suffer life-threatening complication. In the multivariable logistic regression analysis were identified that Female birth attendants (AOR = 2.85; 95% CI 1.57, 5.15), less than three times ANC-visitors (AOR = 2.99; 95% CI 1.39, 6.45), age > 35 years old (AOR = 2.47; 95% CI 1.25, 4.90) and primary school attendants (AOR = 2.13; 95% CI 1.08, 4.17) were significantly associated with obstetrics violence. This study identified that high prevalence of obstetric violence among HIV positive women. Hence, mitigation is needed to be undertaken by taking the reported forms of obstetrics violence, socio-demographic and obstetrics variables by ensuring a systematic and strategic intervention for quality birth care utilization through an inclusive involvement like families, communities, government and stakeholders.</p>","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145846480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-27DOI: 10.1186/s12884-025-08445-8
Ayal Debie, Molla M Wassie, Claire T Roberts, Meseret Derbew Molla, Annabelle Wilson, Jacqueline H Stephens
{"title":"Publisher Correction: Health system responsiveness for maternal healthcare services in East Africa: a mixed-methods systematic review.","authors":"Ayal Debie, Molla M Wassie, Claire T Roberts, Meseret Derbew Molla, Annabelle Wilson, Jacqueline H Stephens","doi":"10.1186/s12884-025-08445-8","DOIUrl":"10.1186/s12884-025-08445-8","url":null,"abstract":"","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":"25 1","pages":"1320"},"PeriodicalIF":2.7,"publicationDate":"2025-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12743396/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145846538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-26DOI: 10.1186/s12884-025-08610-z
Qiuhong Huang, Fengdan Lai, Liubing Lan
Objective: To explore the related factors of spontaneous premature birth (SPB) in pregnant women with gestational diabetes mellitus (GDM), and to construct its nomogram risk prediction model.
Methods: A retrospective collection of clinical data was conducted on 410 GDM patients admitted to our hospital from October 2020 to October 2023 as the training set. In addition, clinical data of 144 GDM patients admitted to our hospital from November 2023 to September 2024 retrospectively were collected as the validation cohort set for external validation. Both groups were separated into SPB group and non-SPB group based on whether SPB occurred.
Results: Logistic analysis of training set showed that age, pre-pregnancy BMI, history of spontaneous abortion, history of infection during pregnancy, family history of diabetes, hypertension, and premature rupture of membranes were the risk factors for SPB in GDM pregnant women (P < 0.05). The AUC of the ROC curve for the discrimination of the training set was 0.850, the optimism-corrected C-index was 0.753,and the H-L test showed χ2 = 6.987 (P = 0.699). DCA curve showed that when the threshold probability was between 0.13 and 0.99, the model had high clinical application value. The external validation results showed that the AUC of the ROC curve was 0.891, the optimism-corrected C-index was 0.771, and the H-L test showed χ2 = 7.016 (P = 0.699), and the threshold probability of the DCA curve results was between 0.11 and 0.87, indicating that the model had high clinical application value.
Conclusion: Age, pre-pregnancy BMI, history of spontaneous abortion, history of infection during pregnancy, family history of diabetes, hypertension, and premature rupture of membranes are the risk factors for SPB in GDM pregnant women. The nomogram prediction model constructed based on these factors has good calibration and discrimination.
{"title":"Analysis of related factors of spontaneous premature birth in pregnant women with gestational diabetes mellitus and construction of its nomogram risk prediction model.","authors":"Qiuhong Huang, Fengdan Lai, Liubing Lan","doi":"10.1186/s12884-025-08610-z","DOIUrl":"https://doi.org/10.1186/s12884-025-08610-z","url":null,"abstract":"<p><strong>Objective: </strong>To explore the related factors of spontaneous premature birth (SPB) in pregnant women with gestational diabetes mellitus (GDM), and to construct its nomogram risk prediction model.</p><p><strong>Methods: </strong>A retrospective collection of clinical data was conducted on 410 GDM patients admitted to our hospital from October 2020 to October 2023 as the training set. In addition, clinical data of 144 GDM patients admitted to our hospital from November 2023 to September 2024 retrospectively were collected as the validation cohort set for external validation. Both groups were separated into SPB group and non-SPB group based on whether SPB occurred.</p><p><strong>Results: </strong>Logistic analysis of training set showed that age, pre-pregnancy BMI, history of spontaneous abortion, history of infection during pregnancy, family history of diabetes, hypertension, and premature rupture of membranes were the risk factors for SPB in GDM pregnant women (P < 0.05). The AUC of the ROC curve for the discrimination of the training set was 0.850, the optimism-corrected C-index was 0.753,and the H-L test showed χ<sup>2</sup> = 6.987 (P = 0.699). DCA curve showed that when the threshold probability was between 0.13 and 0.99, the model had high clinical application value. The external validation results showed that the AUC of the ROC curve was 0.891, the optimism-corrected C-index was 0.771, and the H-L test showed χ<sup>2</sup> = 7.016 (P = 0.699), and the threshold probability of the DCA curve results was between 0.11 and 0.87, indicating that the model had high clinical application value.</p><p><strong>Conclusion: </strong>Age, pre-pregnancy BMI, history of spontaneous abortion, history of infection during pregnancy, family history of diabetes, hypertension, and premature rupture of membranes are the risk factors for SPB in GDM pregnant women. The nomogram prediction model constructed based on these factors has good calibration and discrimination.</p>","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145843668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-26DOI: 10.1186/s12884-025-08592-y
Rodolfo Rosa Japecanga, Juliana da-Costa-Santos, Guilherme Moraes Nobrega, Fernando Guimarães, Fernanda G Surita, José Paulo de Siqueira Guida, Maria Laura Costa
{"title":"Testing the use of a biomarker (PlGF) to evaluate superimposed preeclampsia in pregnant women with chronic hypertension (B.I.P.E.S.): a randomized clinical trial study protocol.","authors":"Rodolfo Rosa Japecanga, Juliana da-Costa-Santos, Guilherme Moraes Nobrega, Fernando Guimarães, Fernanda G Surita, José Paulo de Siqueira Guida, Maria Laura Costa","doi":"10.1186/s12884-025-08592-y","DOIUrl":"https://doi.org/10.1186/s12884-025-08592-y","url":null,"abstract":"","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145843645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-26DOI: 10.1186/s12884-025-08587-9
Karen Trister Grace, Erin K George, Elizabeth A Mosley
Background: "Unintended pregnancy" is a ubiquitous indicator of poor public health, but is highly problematic and limited. A conceptual evolution in pregnancy intention measurement and categorization has led to numerous, often hard-to-compare studies using a multitude of non-binary, multi-dimensional pregnancy measures. Herein we conducted a systematic review of research studying non-binary measures of pregnancy perceptions, attitudes, and reactions, as predictors of public health outcomes.
Methods: Forty-three articles met inclusion criteria. We summarized existing pregnancy measures, cataloged the dimensions of pregnancy they measure, and tracked significant outcomes associated with these measures.
Results: We documented numerous pregnancy-related measures including those on ambivalence, acceptability, timing, intention, emotional response, use of contraception, preparation for pregnancy, opinions/reactions of partners and others, perceived fecundity, readiness, denial, and self-efficacy to prevent pregnancy. The strongest associations with maternal and child health outcomes were observed for depression. Relationships with pregnancy complications and outcomes, postpartum care, breastfeeding, attachment, and child health are very unclear. Temporal confounding precludes many conclusions about psychosocial outcomes.
Conclusions: Acknowledging multiple dimensions of and pathways to pregnancy is critical for researchers in public health, clinical care, and the social sciences. Research questions should be clear in their hypothesized relationships and pathways, and specific in their dimensions of interest. New paradigms are needed that move beyond pregnancy planning and intention.
{"title":"A systematic review of non-binary measures of pregnancy perceptions, attitudes and reactions, and associated outcomes.","authors":"Karen Trister Grace, Erin K George, Elizabeth A Mosley","doi":"10.1186/s12884-025-08587-9","DOIUrl":"https://doi.org/10.1186/s12884-025-08587-9","url":null,"abstract":"<p><strong>Background: </strong>\"Unintended pregnancy\" is a ubiquitous indicator of poor public health, but is highly problematic and limited. A conceptual evolution in pregnancy intention measurement and categorization has led to numerous, often hard-to-compare studies using a multitude of non-binary, multi-dimensional pregnancy measures. Herein we conducted a systematic review of research studying non-binary measures of pregnancy perceptions, attitudes, and reactions, as predictors of public health outcomes.</p><p><strong>Methods: </strong>Forty-three articles met inclusion criteria. We summarized existing pregnancy measures, cataloged the dimensions of pregnancy they measure, and tracked significant outcomes associated with these measures.</p><p><strong>Results: </strong>We documented numerous pregnancy-related measures including those on ambivalence, acceptability, timing, intention, emotional response, use of contraception, preparation for pregnancy, opinions/reactions of partners and others, perceived fecundity, readiness, denial, and self-efficacy to prevent pregnancy. The strongest associations with maternal and child health outcomes were observed for depression. Relationships with pregnancy complications and outcomes, postpartum care, breastfeeding, attachment, and child health are very unclear. Temporal confounding precludes many conclusions about psychosocial outcomes.</p><p><strong>Conclusions: </strong>Acknowledging multiple dimensions of and pathways to pregnancy is critical for researchers in public health, clinical care, and the social sciences. Research questions should be clear in their hypothesized relationships and pathways, and specific in their dimensions of interest. New paradigms are needed that move beyond pregnancy planning and intention.</p>","PeriodicalId":9033,"journal":{"name":"BMC Pregnancy and Childbirth","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145833045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}