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Conjunctival ophthalmomyiasis: about a case in southern Morocco 结膜眼肿病:摩洛哥南部1例
Pub Date : 2019-02-18 DOI: 10.15406/aovs.2019.09.00336
Youssoufou Souley Abdoul Salam, Chammout Fatima Zahra, Elkhoyaali Adil, R. Karim, O. Abdelbarre
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引用次数: 0
Saturday night choroido-retinopathy: a rising clinical entity 周六晚上脉络膜视网膜病变:一个正在崛起的临床实体
Pub Date : 2019-02-06 DOI: 10.15406/aovs.2019.09.00335
B. Turgut, T. Demir
proptosis, ocular pain, diffuse retinal edema and ophthalmoplegia following the opioid or heavy alcohol-induced prone position.1-4 It has been firstly described by Jayam et al in 1974 as the unilateral visual loss due to prolonged pressure on the orbit at stupor and asleep in face-down position.1 It has been called with this name because this clinical pathology occurs following heavy alcohol and abuse of methadone at a Saturday night party.1
阿片类药物或大量酒精诱发的俯卧位后眼球突出、眼痛、弥漫性视网膜水肿和眼麻痹。1-4 Jayam等人在1974年首次将其描述为在昏迷和面朝下睡姿下长时间压迫眼眶导致的单侧视力丧失1之所以叫这个名字,是因为这种临床病理是在周六晚上的聚会上大量饮酒和滥用美沙酮后发生的
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引用次数: 0
Comparative analysis of axial length measurement using partial coherence interferometry and clinical ultrasound 部分相干干涉法与临床超声测量轴长比较分析
Pub Date : 2019-01-31 DOI: 10.15406/aovs.2019.09.00334
Fatima Iqbal, H. Khan
The visual damage caused by cataract cannot be recovered by visual aids and refractive surgeries. The cataract can be removed, undergoing the procedure of cataract surgery. There are many techniques being practiced for extraction of cataract including Extra-capsular cataract extraction, Phacoemulsification, Cool micro incision phacoemulsification, Laser cataract surgery (FEMTO-2). In the developing countries, phacoemulsification is the most preferred procedure. The basic principle, it uses is the ultrasonic waves which travel across the opacified lens and disperse the lens which is then easily extracted.2
白内障造成的视力损害不能通过助视器和屈光手术恢复。白内障可以通过白内障手术摘除。白内障的摘出技术有晶状体外摘出、超声乳化、冷微切口超声乳化、激光白内障手术(FEMTO-2)等。在发展中国家,超声乳化术是最受欢迎的手术。它使用的基本原理是超声波穿过混浊镜片并分散镜片,然后很容易提取
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引用次数: 2
Unilateral blurred vision due to internal carotid artery occlusive disease 颈内动脉闭塞性疾病引起的单侧视力模糊
Pub Date : 2019-01-10 DOI: 10.15406/aovs.2019.09.00331
A. Altıntaş, Cagri Ilhan, M. Çıtırık
The eye globe is a very specialized organ and internal carotid artery (ICA) provides blood supply of eye via ophthalmic artery which is the first intracranial branch of the ICA.1 In ICA occlusive disease (ICAOD), the blood flow in the ophthalmic artery reverses to supply the ipsilateral brain due to incomplete blood circulation at Willis polygon and this phenomenon called as “steal phenomenon”.2 Reduction in perfusion pressure of the ophthalmic artery and its branches especially central retinal artery and posterior ciliary artery, lead the decreased retinal and choroidal circulation and chronic progressive ocular ischemia.3
眼球是一个非常特殊的器官,颈内动脉(ICA)通过眼动脉为眼睛提供血液供应,眼动脉是ICA的第一个颅内分支。1在ICA闭塞性疾病(ICAOD)中,由于Willis polygon的血液循环不完全,眼动脉的血流反向供应同侧大脑,这种现象称为“偷窃现象”眼动脉及其分支特别是视网膜中央动脉和睫状体后动脉灌注压降低,导致视网膜和脉络膜循环减少,慢性进行性眼缺血
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引用次数: 0
Serum irisin levels in chronic open-angle glaucoma 慢性开角型青光眼血清鸢尾素水平
Pub Date : 2019-01-01 DOI: 10.15406/aovs.2019.09.00370
B. Turgut, K. Mercan, N. Ilhan, O. Çatak
Glaucoma is a progressive and neurodegenerative disease characterized by the loss of the axons of retinal ganglion cells (RGCs) at the level of the optic nerve head (ONH) and visual field (VF) loss.1,2 Although elevated intraocular pressure (IOP) is considered as most important factor in the pathogenesis of glaucoma, clinical reports demonstrate that treatment strategies on lowering IOP is not alone enough to prevent glaucoma progression in all patients. Thus, neuroprotection may be crucial in the treatment of glaucoma.3−6 Neuroprotection is defined as the use of therapeutic agents to prevent, reduce, and even to reverse neuronal cell death because of a neurodegenerative disease or a traumatic or a neurotoxic injury. Recent studies demonstrated that several neuroprotective treatments have been established in some neurodegenerative diseases of the central nervous system (CNS) disease like Alzheimer’s disease (AD).7−11 Irisin is an exercise-induced, 112-amino acid glycosylated protein that is formed by the proteolytic cleavage of fibronectin type III domain-containing protein 5 (FNDC5) in muscle tissue. It has been demonstrated that irisin works in the regulation in glucose homeostasis and the convertion of white adipose tissue to brown. Elevated irisin level increase in energy metabolism, weight loss and improves glucose tolerance causes.12−14 Irisin was firstly discovered from mouse skeletal muscle, and it was shown to be present in a variety of a lot of other tissues including rectum, pericardium, intracranial artery, heart, tongue, optic nerve (ON), uvula, brain, ovary, oviduct, pituitary, seminal vesicles, adrenal gland, esophagus, vena cava, kidney, penis, retina, testis, urethra, urinary bladder, spinal cord, liver, small intestine, tonsil, thyroid, and vagina.15 It has been reported that irisin immunoreactivity is present in the neural retina and muscle fibers in the eye of porcupine.16 In another study, it has been demonstrated that irisin immunoreactivity was found in all layers of the retina excluding the outer nuclear layer and also in the cornea in hamsters.17
青光眼是一种进行性神经退行性疾病,其特征是视神经头(ONH)水平的视网膜神经节细胞(RGCs)轴突的丧失和视野(VF)的丧失。虽然眼压升高被认为是青光眼发病的最重要因素,但临床报告表明,仅靠降低眼压的治疗策略不足以预防所有患者的青光眼进展。因此,神经保护在青光眼的治疗中可能至关重要。3 - 6神经保护被定义为使用治疗剂来预防、减少甚至逆转因神经退行性疾病或创伤性或神经毒性损伤而导致的神经元细胞死亡。近年来的研究表明,在一些中枢神经系统(CNS)的神经退行性疾病如阿尔茨海默病(AD)中已经建立了几种神经保护治疗方法。7−11鸢尾素是一种运动诱导的112个氨基酸糖基化蛋白,由肌肉组织中纤维连接蛋白III型结构域蛋白5 (FNDC5)的蛋白水解裂解形成。已经证明鸢尾素在调节葡萄糖稳态和白色脂肪组织向棕色脂肪组织的转化中起作用。鸢尾素水平升高是能量代谢增加、体重减轻和改善葡萄糖耐量的原因。12−14鸢尾素最早是在小鼠骨骼肌中发现的,并被证明存在于许多其他组织中,包括直肠、心包、颅内动脉、心脏、舌头、视神经(ON)、小舌、大脑、卵巢、输卵管、垂体、精囊、肾上腺、食道、腔静脉、肾脏、阴茎、视网膜、睾丸、尿道、膀胱、脊髓、肝脏、小肠、扁桃体、甲状腺和阴道据报道,鸢尾素免疫反应性存在于豪猪眼睛的神经视网膜和肌肉纤维中在另一项研究中,已经证明鸢尾素的免疫反应性存在于除外核层以外的所有视网膜层以及仓鼠的角膜中
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引用次数: 2
Screening for hydroxychloroquine maculopathy 羟氯喹黄斑病变的筛查
Pub Date : 2019-01-01 DOI: 10.15406/aovs.2019.09.00367
E. Selim, Soad Elsawy, S. Verma, Noha Mouselhy, Rehab Auf
Disease-modifying antirheumatic drugs (DMARDs) are a groups of medicines used to alter the course of rheumatological conditions. Chloroquine was first introduced as an antimalarial drug in the Second World War. In countries outside the United States, it is still primarily used as a prophylactic agent against malaria. It is also used, along with its derivatives, as DMARDs in the treatment of Amebiasis, RA and SLE. Chloroquine and its derivatives have an affinity for melanin pigment. Therefore is found is highest levels in uveal tract in the eye and skin. That is where side effect of this Chloroquine and its derivatives are highest.1 Chloroquine and its derivatives are usually administered orally. Bioavailability of HCQ is well around 74% with linear kinetics. It reaches its highest concentration in plasma in about 3 to 4 hours. Patients with rheumatoid arthritis show inverse correlation between disease activity and plasma concentration and hence absorption of HCQ. Higher absorption and concentration is found is patients with less disease activity.2−4
改善疾病的抗风湿药物(DMARDs)是一组用于改变风湿病病程的药物。氯喹最初是在第二次世界大战期间作为抗疟疾药物引入的。在美国以外的国家,它仍然主要被用作预防疟疾的药物。它及其衍生物也作为dmard用于治疗阿米巴病、类风湿性关节炎和系统性红斑狼疮。氯喹及其衍生物对黑色素有亲和力。因此,在眼睛和皮肤的葡萄膜束中发现的含量最高。这就是氯喹及其衍生物的副作用最大的地方氯喹及其衍生物通常口服。在线性动力学下,HCQ的生物利用度在74%左右。它在血浆中约3至4小时达到最高浓度。类风湿关节炎患者的疾病活动性与血药浓度呈负相关,从而导致HCQ的吸收。在疾病活动度较低的患者中发现吸收和浓度较高。2 - 4
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引用次数: 1
Triple optical illusions during laparoscopic TEPP hernioplasty - A case report 腹腔镜TEPP疝成形术中的三重视错觉- 1例报告
Pub Date : 2019-01-01 DOI: 10.15406/aovs.2019.09.00332
Maulana M Ansari
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引用次数: 0
Pixelometric and retinal optical digital biopsy 像素测量和视网膜光学数字活检
Pub Date : 2019-01-01 DOI: 10.15406/aovs.2019.09.00356
J. Zárate
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引用次数: 0
Macular atrophy in neovascular age related macular degeneration 新生血管性年龄相关性黄斑变性的黄斑萎缩
Pub Date : 2019-01-01 DOI: 10.15406/aovs.2019.09.00333
E. Selim, M. Selim
Advanced age related macular degeneration (AMD) is estimated to affect nearly 10 million people worldwide. Late AMD is associated with advancing age, smoking, positive family history, genetic susceptibility, high fat intake and obesity.1–4 It is predicted for advanced macular degeneration to increase in prevalence from the year 2020 to year 2040 by about 65%.1 A large percentage of that increase will be in the form of neovascular age related macular degeneration which is likely to increase in prevalence by about 47% from the year 2020 to the year 2040.2 Age related macular degeneration remains the leading cause of visual loss in people above 50 years old in industrialized countries.
据估计,全球有近1000万人患有高龄相关性黄斑变性(AMD)。晚期AMD与高龄、吸烟、阳性家族史、遗传易感性、高脂肪摄入和肥胖有关。据预测,从2020年到2040年,晚期黄斑变性的患病率将增加约65%这一增长的很大一部分将以新生血管性年龄相关性黄斑变性的形式出现,从2020年到2040年,其患病率可能增加约47%。在工业化国家,年龄相关性黄斑变性仍然是50岁以上人群视力丧失的主要原因。
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引用次数: 7
An interesting case of ocular involvement in a case of dystrophic epidermolysis bullosa with conjunctival blistering without eyelid or corneal disease; a case report 无眼睑或角膜疾病的营养不良大疱性表皮松解伴结膜起泡的有趣病例;病例报告
Pub Date : 2019-01-01 DOI: 10.15406/aovs.2019.09.00337
Das Mohapatra Shyam Sundar, D. Dipankar, B. Harsha, A. Shashank
Epidermolysis bullosa (EB) is an autoimmune mucocutaneous disorder associated with abnormalities of the basement membrane zone of skin and mucous membranes. It is characterized by blister formation in response to minor trauma to the skin and mucous membranes. Here, we present a case of dystrophic epidermolysis bullosa (DEB) in 4years old boy with conjunctival blister formation without eyelid or corneal involvement. He was presented with redness in right eye and active and chronic blistering skin lesions on the elbows, fingers, knees, legs, toes and back of the pinna with scarring in some areas. He had dystrophy of nails and absence of nails in some toes. The oral mucosa was normal and the patient did not have any swallowing complains or other gastrointestinal disorders. A small blister formation was noted in the superior temporal quadrant of conjunctiva in right eye with episcleral congestion. He was diagnosed as a case of autosomal dominant variant of dystrophic epidermolysis bullosa (DDEB), confirmed with biopsy and genetic analysis. So, ophthalmic complications are common in DDEB, but the involvement of ocular structures varies widely among different patients and different subtypes of the disease. Conjunctival blistering without eyelid or corneal disease is one of the most common ophthalmic complications. Protection of the eye from minor trauma such as rubbing may help prevent ocular complications. The major treatment modality is the use of ocular lubricants.
大疱性表皮松解症(EB)是一种自身免疫性粘膜皮肤病,与皮肤和粘膜基底膜区异常有关。它的特点是对皮肤和粘膜的轻微创伤产生水疱。在此,我们报告一例4岁男孩的营养不良性大疱性表皮松解症(DEB),结膜形成水疱而不累及眼睑或角膜。患者表现为右眼发红,肘部、手指、膝盖、腿、脚趾和耳廓后部出现活动性和慢性水泡性皮肤病变,部分区域有瘢痕。他的指甲营养不良,有些脚趾没有指甲。口腔黏膜正常,患者无吞咽不适及其他胃肠道疾病。右眼结膜颞上象限见小水疱形成,伴外膜充血。他被诊断为常染色体显性变异的营养不良大疱性表皮松解症(DDEB),经活检和遗传分析证实。因此,眼部并发症在DDEB中很常见,但不同患者和不同亚型的疾病对眼部结构的累及差异很大。无眼睑或角膜疾病的结膜起泡是最常见的眼科并发症之一。保护眼睛免受轻微创伤,如摩擦,可能有助于预防眼部并发症。主要的治疗方式是使用眼润滑剂。
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Advances in ophthalmology & visual system
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