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Reducing delays in time-critical medications for Parkinson's disease: a multifaceted, multiprofessional quality improvement project. 减少时间紧迫的帕金森病药物的延误:一个多方面、多专业的质量改进项目。
IF 1.6 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-30 DOI: 10.1136/bmjoq-2025-003715
James Fisher, Charlotte Scott

When people with Parkinson's disease (PD) are admitted to hospital, control of their symptoms can deteriorate, often due to delayed or incorrect medication administration. The aim of this project was to improve the administration of PD medicines for hospital in-patients in our trust. Specifically, we aimed to administer 95% of PD medicines within 30 minutes of the prescribed time and to eliminate delays of >60 minutes for PD medications.To achieve these aims, we developed a multifaceted quality improvement project, led by a multidisciplinary team, that ran over a period of 2 years. The outcome measure in this project was the time delay between the time a given PD medicine was scheduled to be administered and the time at which it was recorded as having been administered by nursing staff.The data were divided into 3 phases: a 6-month baseline phase (March 2022 to September 2022), a 24-month project phase (September 2022 to September 2024) and a 6-month sustain phase (September 2024 to March 2025). Statistical process control (SPC) charts were used to monitor medicine delays over time. Plan-do-study-act methodology was adopted within this project and a variety of interventions were employed throughout the project.The project demonstrated a significant reduction in delays in medicines administration for patients with PD. The success of our project came from the cultivation of multiprofessional 'ownership' of the problem, in combination with an appreciation of the patient's lived experience, through visualisation of how poor symptom control can impact on a person's ability to move. Whilst it is not possible to comment on the long-term sustainability of the project, we were encouraged that the changes were maintained throughout the 6-month sustain phase for both medicine administration targets.

当患有帕金森病(PD)的人入院时,他们的症状控制可能会恶化,通常是由于延迟或不正确的药物管理。该项目的目的是改善我们信托医院住院患者PD药物的管理。具体来说,我们的目标是在规定时间的30分钟内给药95%的PD药物,并消除PD药物延迟60分钟。为了实现这些目标,我们开发了一个多方面的质量改进项目,由一个多学科团队领导,历时两年。在这个项目的结果测量是给定的PD药物计划给药的时间和护理人员记录给药的时间之间的时间延迟。数据分为3个阶段:6个月的基线阶段(2022年3月至2022年9月),24个月的项目阶段(2022年9月至2024年9月)和6个月的维持阶段(2024年9月至2025年3月)。统计过程控制(SPC)图表用于监测药物随时间的延迟。该项目采用了计划-研究-行动的方法,并在整个项目中采用了各种干预措施。该项目证明了PD患者药物管理延迟的显著减少。我们项目的成功来自于对问题的多专业“所有权”的培养,结合对患者生活经验的欣赏,通过可视化不良症状控制如何影响一个人的行动能力。虽然不可能对该项目的长期可持续性发表评论,但我们感到鼓舞的是,在整个6个月的维持阶段,两个药物管理目标都保持了这些变化。
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引用次数: 0
From observation to action: a qualitative interview study of factors that influence the reporting of observations of unprofessional conduct in healthcare settings. 从观察到行动:一项定性访谈研究的因素,影响报告的观察不专业的行为在医疗机构。
IF 1.6 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-27 DOI: 10.1136/bmjoq-2025-003853
Lynn E Webb, Gerald B Hickson, Michelle Troyer, William Martinez, Nicolette M Kostiw, William O Cooper

Background: Unprofessional behaviour in healthcare settings can undermine patient safety, erode team morale, and if not addressed, negatively impact organisational culture. Healthcare organisations rely on the voluntary reporting of such behaviours to identify and address these issues. Understanding the factors that influence reporting decisions is essential for pursuing and sustaining a culture of safety and respect.

Objective: To explore the motivations, experiences and attitudes of healthcare professionals who report incidents of perceived unprofessional behaviour through an organisational event reporting system.

Methods: A qualitative study was conducted involving semistructured interviews with 50 healthcare professionals who had submitted reports of unprofessional behaviour at the study site. Thematic analysis was used to identify recurring themes related to the reporters' motivations, reservations, knowledge of the reporting process and considerations for direct communication.

Results: Participants reported being motivated to report primarily by concerns about coworker mistreatment (52%) and patient safety (38%). While most participants (68%) expressed no reservations about reporting, some raised concerns about potential retaliation (32%). Most participants (82%) demonstrated an understanding of the reporting process, and over half (56%) indicated they had attempted to address the issue directly with the colleague involved before submitting a formal report.

Conclusion: Healthcare professionals are motivated to report unprofessional behaviour primarily out of concern for their colleagues and patient safety. Addressing fears of retaliation and promoting transparent reporting processes are essential for fostering a culture of safety and encouraging the reporting of unprofessional conduct. Findings suggest that organisations should continue to emphasise both formal reporting systems and training for direct communication to address unprofessional behaviour effectively.

背景:医疗环境中的不专业行为会破坏患者安全,侵蚀团队士气,如果不加以解决,还会对组织文化产生负面影响。医疗机构依靠自愿报告这些行为来识别和解决这些问题。了解影响报告决策的因素对于追求和维持安全和尊重的文化至关重要。目的:探讨医疗保健专业人员通过组织事件报告系统报告感知到的不专业行为事件的动机、经历和态度。方法:采用半结构化访谈法对50名在研究现场报告有不专业行为的医疗保健专业人员进行定性研究。专题分析用于确定与记者的动机、保留意见、对报道过程的了解和对直接沟通的考虑有关的反复出现的主题。结果:参与者报告的主要动机是担心同事虐待(52%)和患者安全(38%)。虽然大多数参与者(68%)表示对举报没有保留意见,但有些人(32%)表示担心可能遭到报复。大多数参与者(82%)表现出对报告过程的理解,超过一半(56%)的人表示,他们在提交正式报告之前,曾试图直接与相关同事解决问题。结论:医疗保健专业人员报告不专业行为的动机主要是出于对同事和患者安全的关注。消除对报复的恐惧和促进透明的报告程序对于培养安全文化和鼓励报告不专业行为至关重要。调查结果表明,组织应继续强调正式报告制度和直接沟通培训,以有效解决不专业行为。
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引用次数: 0
Phased implementation of surgical safety care bundle in a multispecialty, tertiary care teaching hospital: a quality improvement project. 多专科三级教学医院分阶段实施手术安全护理包:质量改进项目。
IF 1.6 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-27 DOI: 10.1136/bmjoq-2025-003489
Anita Shirley Joselyn, Lallu Joseph, Anitha Loganathan, Joel Ebenezer, Sonia Abraham, Mark Ranjan

Background: 'Safe surgery saves lives' initiative by the WHO consists of measures focussed on improving surgical safety. Healthcare institutions across the globe are encouraged to identify the lacunae in surgical safety and adopt these initiatives to suit the local practices and traditions.

Methods: A few never events and near misses prompted our institution to create a surgical care safety bundle to improve perioperative patient safety. The surgical care bundle focused on improving the usage of surgical safety checklist (SSCL), surgical consents, surgical site marking (SSM) and sponge count in a phased manner. Baseline audits were conducted for each of the above components at different time points and measures were introduced to improve compliance.

Results: The baseline usage of SSCL in 2010 was 65% that improved to 70% in 2014, 86% in 2016 and 97% in 2019. The availability of general surgical consents improved from 56% in 2010 to 70% in 2015. With the introduction of specialised surgical consents in 2019, the compliance improved significantly to 99%. SSM was added to the project in 2017, improved from baseline 74% to 95% in 2019 and continues to remain above 90%. Sponge count documentation has been below 80% in 2010 and was implemented as a part of the safe surgery protocol in 2019 after which compliance significantly improved and stayed above 90%. Good compliance with the usage of checklists and improved the safety culture was demonstrated by increased reporting of near miss events. Never events have not occurred after introduction of all components of surgical safety in 2019.

Conclusion: Phased implementation of surgical care safety bundles, audits and reaudits, repeated educational measures and a slow yet steady process of interventions has markedly improved the safety culture and surgical safety in a larger teaching hospital of a developing country.

背景:世卫组织发起的“安全手术拯救生命”倡议包括以提高手术安全性为重点的措施。鼓励全球的医疗保健机构确定手术安全方面的空白,并采取这些举措,以适应当地的做法和传统。方法:一些从未发生过的事件和侥幸脱险促使我院建立了外科护理安全包,以提高围手术期患者的安全性。手术护理包的重点是分阶段改进手术安全检查表(SSCL)、手术同意书、手术部位标记(SSM)和海绵计数的使用。在不同的时间点对上述每个组成部分进行了基线审计,并引入了措施以改善遵守情况。结果:2010年SSCL的基线使用率为65%,2014年提高到70%,2016年提高到86%,2019年提高到97%。普通外科手术的可获得性从2010年的56%提高到2015年的70%。随着2019年引入专业手术许可,合规率显著提高至99%。SSM于2017年加入该项目,从基线的74%提高到2019年的95%,并继续保持在90%以上。海绵计数文件在2010年低于80%,并于2019年作为安全手术方案的一部分实施,此后依从性显着提高并保持在90%以上。对检查表的使用的良好遵守和安全文化的改进通过增加对未遂事件的报告来证明。在2019年引入手术安全的所有组成部分后,没有任何事件不发生。结论:某发展中国家某大型教学医院分阶段实施手术护理安全包、审核和再审核、反复教育措施和缓慢而稳定的干预措施,显著改善了安全文化和手术安全。
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引用次数: 0
Cultural transformation beyond checklists for patient safety: a longitudinal evaluation of safety interventions in critical care. 超越病人安全检查表的文化转型:对重症监护安全干预措施的纵向评估。
IF 1.6 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-27 DOI: 10.1136/bmjoq-2025-003760
Alessio Caccioppola, Lucia Villa, Irene Zainaghi, Matteo Brioni, Veronica Rossi, Emilia Privitera, Paolo Properzi, Sara Leoni, Paola Roselli, Andrea Cislaghi, Ileana Adamini, Giacomo Grasselli, Mauro Panigada

Background: Implementing structured safety interventions in intensive care units (ICUs) remains challenging due to patient complexity, staff turnover and dynamic workflows. This study evaluates the longitudinal impact of a multidisciplinary safety improvement programme in a high-acuity ICU.

Methods: A 2-year prospective evaluation was conducted in a 12-bed academic ICU in Milan, Italy. The Hospital Survey on Patient Safety Culture was administered to all ICU professionals (physicians, nurses, physiotherapists) in December 2022 and repeated in December 2024. Interventions included staff training, enhanced event reporting systems, regular morbidity and mortality conferences and a multidisciplinary safety team. Responses were analysed descriptively, including subgroup analysis by professional category and staff turnover.

Results: A total of 86 staff completed the 2022 survey, and 66 completed the 2024 survey, with 56 participating in both. Over the 2 years, perceptions of teamwork (68%-81%), communication openness (47%-60%) and comfort in reporting errors (38%-55%) showed substantial improvement. The proportion of staff who perceived management support for safety increased from 70%-80%. Staff hired after 2022 reported more favourable safety perceptions than continuing staff, particularly in communication and reporting domains.

Conclusions: Structured, multidisciplinary interventions led to measurable improvements in ICU safety culture. However, persistent interprofessional differences and under-reporting of adverse events highlight the need for targeted strategies. Safety culture transformation requires sustained leadership, continuous onboarding and system-focused feedback mechanisms to ensure long-term impact.

背景:由于患者复杂性、员工流动率和动态工作流程,在重症监护病房(icu)实施结构化安全干预仍然具有挑战性。本研究评估了一项多学科安全改进方案在高锐ICU的纵向影响。方法:在意大利米兰一家12张床位的学术ICU进行2年前瞻性评价。于2022年12月对所有ICU专业人员(医生、护士、物理治疗师)进行患者安全文化医院调查,并于2024年12月重复调查。干预措施包括工作人员培训、加强事件报告系统、定期召开发病率和死亡率会议以及一个多学科安全小组。对答复进行了描述性分析,包括按专业类别和工作人员流动率进行分组分析。结果:共有86名员工完成了2022年的调查,66名员工完成了2024年的调查,其中56名员工同时参与了这两项调查。2年来,员工对团队合作(68%-81%)、沟通开放性(47%-60%)和报告错误的舒适度(38%-55%)的认知均有显著改善。员工认为管理层支持安全的比例从70%增加到80%。2022年之后聘用的员工比继续聘用的员工对安全的看法更有利,尤其是在沟通和报告领域。结论:结构化的多学科干预导致了ICU安全文化的显著改善。然而,持续的专业间差异和不良事件的低报突出了有针对性策略的必要性。安全文化转型需要持续的领导、持续的入职和以系统为中心的反馈机制,以确保长期影响。
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引用次数: 0
Implementing quality improvement in vascular services: a qualitative study. 实施血管服务质量改进:一项定性研究。
IF 1.6 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-27 DOI: 10.1136/bmjoq-2025-003727
Panagiota Birmpili, Eleanor Atkins, Jon R Boyle, Ian Chetter, David A Cromwell, Liz Glidewell, Laura Sheard

Background: The Peripheral Arterial Disease Quality Improvement Programme (PAD QIP) was a quality improvement (QI) collaborative between 11 English vascular surgery centres from May 2020 to May 2022, aiming to expedite treatment for PAD. This qualitative study explored beliefs about the PAD QIP and barriers and facilitators to implementation of changes in vascular surgery.

Methods: Sixteen semi-structured interviews were conducted with clinicians from the vascular centres that participated in the PAD QIP and were analysed using framework analysis, based on the five broad domains within the Consolidated Framework for Implementation Research.

Results: Five themes captured the main factors that affected the implementation of changes in the pathway of patients with chronic limb-threatening ischaemia: the programme, the benefit for patients, the role of the team, the resources and organisational processes, and the polarising effect of COVID-19. Regarding the programme, participants stated that the concrete timeframes, external performance monitoring, peer comparison and the programme's national reach helped them obtain resources to implement changes. Learning from and sharing experiences with others was also useful. Accurate performance data were considered essential for leveraging resources, but data entry was onerous and required dedicated staff. The view that the programme was beneficial for patients, the support of a team of healthcare professionals and organisational support in the form of resources were important requirements for implementation, while the COVID-19 pandemic also played a crucial role as a contextual factor beyond the control of the participants. The main factors that differed between high-implementation and low-implementation centres were team beliefs, team structure, team compatibility, networks/communication, resources, implementation climate, relative priority and evidence strength.

Conclusions: This QI collaborative facilitated the implementation of changes according to participants, while team and organisational support was crucial.

背景:外周动脉疾病质量改善计划(PAD QIP)是2020年5月至2022年5月期间11个英国血管外科中心之间的质量改善(QI)合作项目,旨在加快PAD的治疗。本定性研究探讨了人们对PAD QIP的看法,以及血管外科实施变革的障碍和促进因素。方法:与参与PAD QIP的血管中心的临床医生进行了16次半结构化访谈,并基于实施研究统一框架中的五个广泛领域,使用框架分析进行了分析。结果:五个主题涵盖了影响慢性肢体威胁性缺血患者途径改变实施的主要因素:方案、患者受益、团队的作用、资源和组织流程以及COVID-19的两极分化效应。关于方案,与会者说,具体的时间表、外部执行情况监测、同行比较和方案的国家范围帮助他们获得资源来执行改革。向他人学习和分享经验也很有用。准确的性能数据被认为是利用资源的必要条件,但数据输入工作繁重,需要专门的工作人员。认为该方案有利于患者,医疗保健专业人员团队的支持和资源形式的组织支持是实施的重要要求,而COVID-19大流行作为参与者无法控制的背景因素也发挥了至关重要的作用。高执行度中心与低执行度中心的主要差异因素为团队信念、团队结构、团队兼容性、网络/沟通、资源、执行氛围、相对优先级和证据强度。结论:根据参与者的意见,这种QI协作促进了变革的实施,而团队和组织的支持至关重要。
{"title":"Implementing quality improvement in vascular services: a qualitative study.","authors":"Panagiota Birmpili, Eleanor Atkins, Jon R Boyle, Ian Chetter, David A Cromwell, Liz Glidewell, Laura Sheard","doi":"10.1136/bmjoq-2025-003727","DOIUrl":"10.1136/bmjoq-2025-003727","url":null,"abstract":"<p><strong>Background: </strong>The Peripheral Arterial Disease Quality Improvement Programme (PAD QIP) was a quality improvement (QI) collaborative between 11 English vascular surgery centres from May 2020 to May 2022, aiming to expedite treatment for PAD. This qualitative study explored beliefs about the PAD QIP and barriers and facilitators to implementation of changes in vascular surgery.</p><p><strong>Methods: </strong>Sixteen semi-structured interviews were conducted with clinicians from the vascular centres that participated in the PAD QIP and were analysed using framework analysis, based on the five broad domains within the Consolidated Framework for Implementation Research.</p><p><strong>Results: </strong>Five themes captured the main factors that affected the implementation of changes in the pathway of patients with chronic limb-threatening ischaemia: the programme, the benefit for patients, the role of the team, the resources and organisational processes, and the polarising effect of COVID-19. Regarding the programme, participants stated that the concrete timeframes, external performance monitoring, peer comparison and the programme's national reach helped them obtain resources to implement changes. Learning from and sharing experiences with others was also useful. Accurate performance data were considered essential for leveraging resources, but data entry was onerous and required dedicated staff. The view that the programme was beneficial for patients, the support of a team of healthcare professionals and organisational support in the form of resources were important requirements for implementation, while the COVID-19 pandemic also played a crucial role as a contextual factor beyond the control of the participants. The main factors that differed between high-implementation and low-implementation centres were team beliefs, team structure, team compatibility, networks/communication, resources, implementation climate, relative priority and evidence strength.</p><p><strong>Conclusions: </strong>This QI collaborative facilitated the implementation of changes according to participants, while team and organisational support was crucial.</p>","PeriodicalId":9052,"journal":{"name":"BMJ Open Quality","volume":"15 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12853451/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146060007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality improvement for self-management: the DIALOG+QI framework. 自我管理的质量改进:DIALOG+QI框架。
IF 1.6 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-22 DOI: 10.1136/bmjoq-2025-003812
Pedro Delgado, Carlos Santos, Lenna Adley, Amar Shah
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引用次数: 0
Food on demand delivery service: from hospitality to hospital - trialling a proof of concept in a specialist children's hospital. 按需送餐服务:从酒店到医院——在一家儿童专科医院进行概念验证试验。
IF 1.6 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-22 DOI: 10.1136/bmjoq-2025-003465
Jo Wray, Charlotte Bexson, Rudi Keyser, Paul Gough, Brittany Rothman, Geralyn Oldham, Andrew Taylor

Objectives: Hospital food influences experiences and outcomes of care, and optimising nutrition for hospitalised children is universally recognised as important for recovery. While several barriers to oral food intake have been identified, interventions to address them are limited. Our aim was to implement and evaluate a proof-of-concept (PoC) trial of a Food on Demand Delivery Service app in a specialist paediatric hospital.

Design: PoC trial and evaluation.

Setting: Specialist children's hospital.

Participants: 101 families completed baseline measures; 26 families completed measures during the PoC trial, 18 parents and 11 ward-based staff participated in interviews, and four ward-based staff and four catering staff took part in focus groups.

Intervention: Following adaptations to an existing web-based Food on Demand Delivery Service app, a PoC trial was undertaken on six inpatient wards during a 4-week period. Data were collected before and following implementation, using quantitative (surveys) and qualitative (focus groups and individual interviews) approaches.

Results: The Food on Demand Delivery Service was positively evaluated by all stakeholder groups. Challenges were identified, particularly by catering staff in relation to communication and logistics, but overall findings supported upscaling to a hospital-wide roll-out.

Conclusion: The Food on Demand Delivery Service offers potential for addressing barriers to oral intake for hospitalised children. Challenges will need to be addressed prior to scaling up the project for a hospital-wide roll-out, and several recommendations came from the trial. However, the benefits for children, families and staff were evident and supported further work to enable the Food on Demand Delivery Service to be introduced across the hospital.

目的:医院食物影响护理的体验和结果,优化住院儿童的营养被普遍认为对康复很重要。虽然已经确定了口服食物摄入的几个障碍,但解决这些障碍的干预措施有限。我们的目标是在一家儿科专科医院实施和评估按需食品配送服务应用程序的概念验证(PoC)试验。设计:PoC试验和评估。环境:儿童专科医院。参与者:101个家庭完成基线测量;在PoC试验期间,26个家庭完成了测量,18名家长和11名病房工作人员参加了访谈,4名病房工作人员和4名餐饮工作人员参加了焦点小组。干预措施:在对现有的基于网络的随需应变食品配送服务应用程序进行调整后,在6个住院病房进行了为期4周的PoC试验。采用定量(调查)和定性(焦点小组和个人访谈)方法,在实施前后收集数据。结果:按需送餐服务得到了所有利益相关者群体的积极评价。确定了挑战,特别是餐饮工作人员在通信和物流方面的挑战,但总体调查结果支持将其升级为在医院范围内推广。结论:按需送餐服务为解决住院儿童口腔摄入障碍提供了潜力。在将该项目扩大到整个医院之前,需要解决一些挑战,并从试验中提出了一些建议。然而,对儿童、家庭和工作人员的好处是显而易见的,并支持进一步开展工作,使按需提供食品服务能够在整个医院推广。
{"title":"Food on demand delivery service: from hospitality to hospital - trialling a proof of concept in a specialist children's hospital.","authors":"Jo Wray, Charlotte Bexson, Rudi Keyser, Paul Gough, Brittany Rothman, Geralyn Oldham, Andrew Taylor","doi":"10.1136/bmjoq-2025-003465","DOIUrl":"10.1136/bmjoq-2025-003465","url":null,"abstract":"<p><strong>Objectives: </strong>Hospital food influences experiences and outcomes of care, and optimising nutrition for hospitalised children is universally recognised as important for recovery. While several barriers to oral food intake have been identified, interventions to address them are limited. Our aim was to implement and evaluate a proof-of-concept (PoC) trial of a Food on Demand Delivery Service app in a specialist paediatric hospital.</p><p><strong>Design: </strong>PoC trial and evaluation.</p><p><strong>Setting: </strong>Specialist children's hospital.</p><p><strong>Participants: </strong>101 families completed baseline measures; 26 families completed measures during the PoC trial, 18 parents and 11 ward-based staff participated in interviews, and four ward-based staff and four catering staff took part in focus groups.</p><p><strong>Intervention: </strong>Following adaptations to an existing web-based Food on Demand Delivery Service app, a PoC trial was undertaken on six inpatient wards during a 4-week period. Data were collected before and following implementation, using quantitative (surveys) and qualitative (focus groups and individual interviews) approaches.</p><p><strong>Results: </strong>The Food on Demand Delivery Service was positively evaluated by all stakeholder groups. Challenges were identified, particularly by catering staff in relation to communication and logistics, but overall findings supported upscaling to a hospital-wide roll-out.</p><p><strong>Conclusion: </strong>The Food on Demand Delivery Service offers potential for addressing barriers to oral intake for hospitalised children. Challenges will need to be addressed prior to scaling up the project for a hospital-wide roll-out, and several recommendations came from the trial. However, the benefits for children, families and staff were evident and supported further work to enable the Food on Demand Delivery Service to be introduced across the hospital.</p>","PeriodicalId":9052,"journal":{"name":"BMJ Open Quality","volume":"15 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12829393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146028250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of real-world evidence from patient registries for psoriasis in decision-making: a systematic review. 来自牛皮癣患者登记的真实世界证据在决策中的作用:系统回顾。
IF 1.6 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-12 DOI: 10.1136/bmjoq-2024-003291
Lauren Passero, Teresa A Simon, Yichen Zhong, Joe Zhuo, Stefan Varga, April W Armstrong

Introduction: Treatment of moderate to severe psoriasis typically requires the use of multiple systemic therapies over a patient's lifetime. The efficacy and safety of systemic treatments are typically evaluated in clinical trials; however, patient registries are increasingly used to monitor long-term outcomes of systemic therapies for psoriasis in real-world settings. Psoriasis registries also generate important real-world evidence about psoriasis treatment that may facilitate a greater understanding of outcomes outside of a controlled clinical trial setting. This study thus characterises the design and measures used in real-world studies of psoriasis treatment from patient registries and assesses its use in informing clinical guidelines and reimbursement decisions.

Methods and analysis: A systematic literature review was conducted to identify real-world observational studies that used psoriasis registry data. PubMed and Embase were searched for English-language studies published between January 2018 and January 2023. To assess how real-world studies, clinical guidelines, and reimbursement and coverage reports have informed practice, treatment, and reimbursement guidelines, a narrative review of recommendations was conducted. All results were screened by two independent reviewers (LP and TAS) using prespecified inclusion and exclusion criteria. Outcomes of interest were extracted into Excel, with all conflicts resolved through discussion/consensus. Tables displayed outcomes and research topics first by year, then by registry.

Prospero registration number: CRD42023402431.

简介:中度至重度牛皮癣的治疗通常需要在患者一生中使用多种全身治疗。全身治疗的有效性和安全性通常在临床试验中进行评估;然而,在现实世界中,患者登记越来越多地用于监测银屑病全身治疗的长期结果。牛皮癣登记也产生了关于牛皮癣治疗的重要现实证据,这可能有助于更好地了解对照临床试验设置之外的结果。因此,本研究从患者登记中描述了银屑病治疗的实际研究中使用的设计和措施,并评估了其在通知临床指南和报销决策中的使用。方法和分析:进行了系统的文献综述,以确定使用牛皮癣登记数据的现实世界观察性研究。在PubMed和Embase检索2018年1月至2023年1月间发表的英语研究。为了评估真实世界的研究、临床指南、报销和覆盖报告如何为实践、治疗和报销指南提供信息,对建议进行了叙述性回顾。所有结果由两位独立的审稿人(LP和TAS)使用预先指定的纳入和排除标准筛选。将感兴趣的结果提取到Excel中,所有冲突都通过讨论/共识解决。表格首先按年份显示结果和研究主题,然后按注册表显示。普洛斯彼罗注册号:CRD42023402431。
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引用次数: 0
Exploring music preferences, behaviours and experiences of exercising to music in pulmonary rehabilitation for individuals with chronic respiratory diseases: a cross-sectional survey. 慢性呼吸系统疾病患者肺部康复过程中音乐偏好、行为和体验的探讨:一项横断面调查。
IF 1.6 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-12 DOI: 10.1136/bmjoq-2025-003666
Omar A Alhothaly, Linzy Houchen-Wolloff, Sarah Ward, Emma Chaplin, Jakub Zatloukal, Mark Dunlop, Sally J Singh, Mark W Orme

Background: Music can enhance exercise performance, but its potential has not been well explored in pulmonary rehabilitation (PR). The aim was to explore the current music-related behaviours among PR service users with chronic respiratory diseases (CRDs) to inform future PR service interventions and explore the potential for music to facilitate exercise adherence in this context.

Methods: The cross-sectional survey was distributed among PR attendees at the University Hospitals of Leicester (UHL) NHS Trust in the United Kingdom, between November 2023 and August 2024. Participants completed a 25-item survey exploring (i) relevant technology ownership and music-related behaviours, (ii) preferred music genres and songs and (iii) anticipated benefits/concerns of exercising to music. Quantitative data were analysed descriptively. Free-text data were analysed using qualitative counting.

Results: We surveyed 109 people living with CRDs (51% male, 56% aged ≥70 year, 76% chronic obstructive pulmonary disease, 82% owned a smartphone). More than half had no prior experience of exercising to music (n=59, 54%). Despite this, almost half of participants listened to music at least once/day (n=54, 49%), primarily via the radio (n=83, 76%) and/or online music platforms (n=76, 70%). Pop (n=39, 36%) and Country (n=38, 35%) were the most popular music genres listened to, with the majority listening to music without headphones (n=64, 59%). The main concern about wearing headphones while exercising was that it might reduce their awareness of the surroundings (n=67, 61%). The perceived benefits of listening to music during exercise were to boost their mood (n=39, 36%) or help maintain their walking pace (n=19, 17%).

Conclusion: There is potential to use music as a tool to support exercise in PR. However, lack of prior experience exercising to music, diverse music preferences, safety considerations and the need to increase knowledge of the potential benefits of exercising to music are key challenges. These findings may help future PR services to implement music into their programmes and develop personalised music-based interventions to optimise exercise performance.

背景:音乐可以提高运动表现,但其在肺康复(PR)中的潜力尚未得到很好的挖掘。目的是探索慢性呼吸系统疾病(CRDs)公关服务用户当前与音乐相关的行为,为未来的公关服务干预提供信息,并探索音乐在这种情况下促进运动坚持的潜力。方法:横断面调查于2023年11月至2024年8月在英国莱斯特大学医院(UHL) NHS信托的公关参与者中进行。参与者完成了一项25项调查,探讨(i)相关技术所有权和与音乐相关的行为,(ii)喜欢的音乐类型和歌曲,以及(iii)对音乐锻炼的预期好处/担忧。定量数据进行描述性分析。使用定性计数对自由文本数据进行分析。结果:我们调查了109名慢性阻塞性肺病患者(51%为男性,56%年龄≥70岁,76%患有慢性阻塞性肺病,82%拥有智能手机)。超过一半的人之前没有听音乐锻炼的经验(n=59, 54%)。尽管如此,几乎一半的参与者每天至少听一次音乐(n= 54,49%),主要是通过广播(n= 83,76%)和/或在线音乐平台(n= 76,70%)。流行音乐(n= 39,36%)和乡村音乐(n= 38,35%)是最受欢迎的音乐类型,大多数人不戴耳机听音乐(n= 64,59%)。在锻炼时戴耳机的主要担忧是它可能会降低他们对周围环境的认识(n= 67,61%)。人们认为在锻炼时听音乐的好处是改善情绪(n= 39,36%)或帮助保持步行速度(n= 19,17%)。结论:利用音乐作为一种工具来支持PR中的锻炼是有潜力的。然而,缺乏之前的音乐锻炼经验,不同的音乐偏好,安全考虑以及需要增加对音乐锻炼潜在益处的了解是关键的挑战。这些发现可能有助于未来的公关服务将音乐融入到他们的项目中,并开发个性化的基于音乐的干预措施来优化运动表现。
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引用次数: 0
Quality improvement project to improve blood culture volumes in haematology patients. 提高血液病患者血培养量的质量改进工程。
IF 1.6 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-01-09 DOI: 10.1136/bmjoq-2025-003497
Chan Yuen Yue Candice, Tan Yen Ee, Tee Ning, Ng Hui Ling Dorothy, Wong Hei Man Anson, Chan Fu Zi Yvonne, Sim Xiang Ying Jean, Cheong May Anne, Khaing Mon Nanda Kyaw Isabella, Chlebicki Maciej Piotr

Sepsis resulting from bloodstream infection is a medical emergency, especially in immunocompromised haematology patients. Identification of causative pathogens through blood cultures is crucial for delivering effective antibiotics promptly.Adequate blood culture volumes (BCV) are crucial for detecting bloodstream infections. Guidelines recommend 8-10 mL per blood culture bottle, yet achieving these volumes remains challenging. In our haematology wards, baseline mean BCV was suboptimal at 4.5 mL. This quality improvement project aimed to optimise BCVs to recommended levels within 6 months at a Singapore tertiary hospital's Department of Haematology.We implemented a multistakeholder quality improvement across three haematology wards from January 2023 to January 2025. Three Plan-Do-Study-Act cycles were executed from July 2024: (1) staff education and stakeholder engagement, (2) equipment and process enhancement and (3) validation of BCV measurements through comparison of an automated BCV measurement system (BD EpiCenter BACTEC Microbiology Data Management System) against manual bottle weighing.Postintervention data demonstrated clear statistical signals of improvements in BCV through both EpiCenter automated system and manual bottle weighing. Manual validation in selected wards demonstrated achievement of target volumes. Importantly, this validation process revealed potential limitations of automated measurement systems in our specialised clinical setting. Overall, our results demonstrate that a well-coordinated, multidisciplinary approach combining staff education and engagement, improved equipment and BCV measurement process can successfully achieve recommended BCV in our complex haematology settings.

血液感染引起的脓毒症是一种医学紧急情况,特别是在免疫功能低下的血液病患者中。通过血培养鉴定致病菌对于及时提供有效的抗生素至关重要。足够的血培养量(BCV)对于检测血流感染至关重要。指南建议每个血培养瓶8-10毫升,但实现这些体积仍然具有挑战性。在我们的血液科病房,基线平均BCV为4.5 mL,不理想。该质量改进项目旨在在6个月内将新加坡一家三级医院血液科的bcv优化到推荐水平。从2023年1月到2025年1月,我们在三个血液科病房实施了多利益相关者质量改进。从2024年7月开始执行了三个计划-执行-研究-行动周期:(1)员工教育和利益相关者参与;(2)设备和工艺改进;(3)通过比较自动BCV测量系统(BD EpiCenter BACTEC微生物数据管理系统)和手动称重来验证BCV测量。干预后的数据显示,通过EpiCenter自动系统和手动称重,BCV得到了明显的改善。选定病房的人工验证证明了目标容量的实现。重要的是,该验证过程揭示了自动化测量系统在我们专业临床环境中的潜在局限性。总体而言,我们的研究结果表明,在我们复杂的血液学环境中,结合员工教育和参与、改进设备和BCV测量过程的协调良好的多学科方法可以成功实现推荐的BCV。
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