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Effects of Diagnostic Mydriasis with Tropicamide and Phenylephrine on Intraocular Pressure Tropicamide和Phenylephrine对眼压的影响
Pub Date : 2019-02-15 DOI: 10.24966/OCR-8887/100049
B. Fiebai
Purpose: To determine the effects of diagnostic mydriasis using 1% tropicamide and 2.5% phenylephrine on the intraocular pressure of patients attending the Eye Clinic of University of Port Harcourt Teaching Hospital. Methods: This was an interventional ‘within-patient’ comparative hospital-based study conducted over 3 months, in which the right eyes of 137 subjects requiring diagnostic mydriasis received 1% tropicamide and 2.5% phenylephrine. The left eyes served as control. Results: There were 137 study participants: 86 males (62.8%) and 51 females (37.2%). The mean age of participants was 44.87±15.94 years. The baseline IOPs were 12.34±3mmHg for the Right Eye (RE) and 12.09±2.64mmHg for the Left Eye (LE). The mean post dilatation IOP at 30, 45, 60, 90 and 120 minutes in the RE were higher than baseline. The maximum mean post dilatation IOP in the RE was 13.75±2.99mmHg and this occurred at 45 minutes. In the control undilated LE, the mean post dilatation IOPs were lower than baseline at all the follow up periods except at 45 minutes where it was slightly higher (12.11±2.87mmHg). These differences in mean IOP change were statistically significant (p<0.05). At all the follow-up periods, 8.8%-14.6% of participant’s right eyes had large IOP elevations (>5mmHg but <10mmHg). Multiple linear regression analysis showed that pre dilatation IOPs were positively correlated to post dilatation IOPs. Conclusion: There is need to recheck IOP post dilatation preferably at 45 minutes in all patients who have had diagnostic mydriasis to prevent damage to the optic nerve. Diagnostic mydriasis could safely be done using small concentrations of tropicamide and phenylephrine.
目的:探讨1%托品酰胺和2.5%苯肾上腺素对哈考特港大学教学医院眼科门诊患者眼压的影响。方法:这是一项为期3个月的以医院为基础的介入性“患者内部”比较研究,其中137名需要诊断性散瞳的受试者的右眼接受1%的tropicamide和2.5%的phenylephrine。左眼作为对照。结果:共纳入137例研究对象,其中男性86例(62.8%),女性51例(37.2%)。参与者平均年龄44.87±15.94岁。基线IOPs右眼(RE) 12.34±3mmHg,左眼(LE) 12.09±2.64mmHg。RE中30,45,60,90,120分钟的平均扩张后IOP高于基线。RE的最大平均扩张后IOP为13.75±2.99mmHg,发生在45分钟。在对照组未扩张LE中,除45分钟稍高(12.11±2.87mmHg)外,所有随访期间的平均扩张后IOPs均低于基线。平均眼压变化差异有统计学意义(p5mmHg, <10mmHg)。多元线性回归分析表明,扩张前IOPs与扩张后IOPs呈正相关。结论:为防止视神经损伤,所有诊断为瞳孔肿大的患者均应在扩眼后45分钟复查IOP。使用小浓度的tropicamide和phenylephrine可以安全地诊断丝虫病。
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引用次数: 4
Edema Palpebral Revealing in a Dermatobia hominis Infection: A Case Report 人皮癣感染引起的眼睑水肿1例
Pub Date : 2019-02-15 DOI: 10.24966/ocr-8887/100048
Diomandé Gossé François
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引用次数: 0
Retinal Detachment Indicative of Choroidal Metastasis of Pulmonary Adenocarcinoma 视网膜脱离预示肺腺癌脉络膜转移
Pub Date : 2019-02-15 DOI: 10.24966/OCR-8887/100050
Y. Mouzari
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引用次数: 1
Eye Complications of Chicken Pox in Port Harcourt Nigeria: Report of 4 Cases 尼日利亚哈科特港水痘眼部并发症4例报告
Pub Date : 2019-02-15 DOI: 10.24966/ocr-8887/100047
C. Pedro-Egbe
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引用次数: 0
Terson Syndrome with Traumatic Optic Atrophy Terson综合征伴外伤性视神经萎缩
Pub Date : 2019-01-01 DOI: 10.33140/jocr.03.01.3
S. Chowdhury, S. Kumari, Priti
A 38 year old male came to our hospital with history of RTA 4 months back, he sustained head injury and was treated outside for brachial plexopathy. He now presented with total loss of vision in left eye which was sudden in onset and non-progressive.
一名38岁男性,4个月前因RTA病史来我院就诊,头部受伤,接受外前臂神经丛病治疗。他现在表现为左眼完全失明,这是突然发作和非进行性的。
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引用次数: 0
Treatment of Macular Degeneration and Other Incurable Eye Ailments with theHelp of Assimilated Technique 利用同化技术治疗黄斑变性和其他无法治愈的眼疾
Pub Date : 2018-12-10 DOI: 10.33140/jocr.02.04.00003
I am trying to pen an article on technique developed over theyears here, Acupuncture India Centre for treatment of MacularDegeneration, Retinitis Pigmentosa, Retinal Degeneration and OpticNerve atrophy. This technique is named as Assimilated Technique andhas been given an ISO certification, AN ISO9001:2008 Certification.
我想写一篇关于多年来在这里发展起来的技术的文章,针灸印度中心治疗黄斑变性、色素性视网膜炎、视网膜变性和视神经萎缩。该技术被命名为同化技术,并获得了ISO认证,an ISO9001:2008认证。
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引用次数: 0
Spectral Domain Optical Coherence Tomography of a Patient with Acute Retinal Pigment Epithelitis 急性视网膜色素上皮炎患者的光谱域光学相干断层扫描
Pub Date : 2018-12-10 DOI: 10.33140/jocr/02/04/00002
Introduction: Acute retinal pigment epithelitis or Krill’s disease first time was described in 1972 as unknown disease and selflimiting inflammatory disorder that influence retinal pigment epithelium in the area of macula. Affecting most of all young adults. Disease equally affects males and females. Symptoms are characterized by sudden changes in vision. The etiology of ARPE is unknown, but there are suggestions that viral infection may play role in the pathogenesis. The diagnosis of ARPE is made based on clinical suspicion, as well as fundus findings. The purpose of this case is to report the clinical changes, laboratory changes and objective spectral domain optical tomography images of an ARPE at the acute phase and resolving phase. Clinical Observation: 28 years old female with subjective complains of blurring in her left eye was examined with OCT scan, vision test, refractometry, laboratory testing was taken in his acute phase of ARPE and then the patient was treated 20 days and after the examination was repeated. There were changes in subjective symptoms and objective there was positive changes in vision test, OCT scan also showed significant positive changes in foveal map, epithelium dislocation. Conclusion: ARPE has a different objective findings during different phases of illness in OCT scan, vision testing, and also in subjective patient complains. ARPE is self-limiting disease, but treatment with oral steroids also might influence development of a disease.
引言:急性视网膜色素上皮炎或Krill病于1972年首次被描述为影响黄斑区域视网膜色素上皮的未知疾病和自限性炎症性疾病。影响大多数年轻人。疾病同样影响男性和女性。症状的特点是视力突然改变。ARPE的病因尚不清楚,但有迹象表明病毒感染可能在发病机制中发挥作用。ARPE的诊断是基于临床怀疑以及眼底检查结果。本病例的目的是报告急性期和分辨期ARPE的临床变化、实验室变化和客观光谱域光学断层扫描图像。临床观察:28岁女性,主观主诉左眼模糊,采用OCT扫描、视力测试、屈光度计进行检查,在ARPE急性期进行实验室测试,然后在患者治疗20天后重复检查。主观症状和客观症状都有变化。视力测试有阳性变化,OCT扫描也显示中央凹图、上皮错位有显著的阳性变化。结论:ARPE在OCT扫描、视力测试和主观患者投诉的不同疾病阶段有不同的客观表现。ARPE是一种自限性疾病,但口服类固醇治疗也可能影响疾病的发展。
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引用次数: 0
Exophthalmos and Blindness Revealing a Non-Hodgkin’s Malignant LymphomaType B with High Grade of Malignancy 高度恶性的非霍奇金B型恶性淋巴瘤的突出眼和失明
Pub Date : 2018-11-26 DOI: 10.33140/jocr/02/04/00001
Background: Non-Hodgkin’s lymphomas represent a heterogeneous group of haematological disorders characterizedby a malignant monoclonal proliferation of the lymphoid system (B or T cells). Orbicatory lolisation is rare, it is seenmainly in adults.Case Report: We report the case of a 79-year-old patient with a high-grade NHML, revealed by blindness and leftexophthalmos evolving for 3 months. Ophthalmological examination revealed left blindness with axil exophthalmosgrade 1. MRI cranio-orbital objectified a left orbital processe lesion intra and extra conical associated with a mucosalthickening of the cavum with left necrotic jugulocarotidian adenopathies. A biopsy of the cavum and ADP objectifieda NHML of type B with high grade of malignancy.Result: The patient was put on induction chemotherapy first before being placed on radiotherapy. The evolution wasmarked by the regression of the left exophthalmia.Conclusion: The NHML is characterized by an extreme clinical polymorphism, especially in the cervicofaciallocalizations, make the diagnosis difficult and lead to a delay in management.
背景:非霍奇金淋巴瘤是一组异质性血液病,其特征是淋巴系统(B或T细胞)的恶性单克隆增殖。Orbicaly lolisa是罕见的,它主要出现在成年人身上。病例报告:我们报告了一例79岁的高级别NHML患者,其表现为失明和左眼突出持续3个月。眼科检查显示左盲伴眼腋突出1级。MRI颅眶客观化了左侧眶突圆锥内和圆锥外病变,该病变与左侧坏死的颈豆状腺病变的腔粘膜增厚有关。腔和ADP的活检对象为B型高恶性NHML。结果:患者在放疗前先进行诱导化疗。进化的标志是左侧突眼的消退。结论:NHML具有极端的临床多态性,尤其是在颈面部定位,使诊断困难并导致治疗延迟。
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引用次数: 0
Earliest Detection of Asymptomatic Glaucoma (POAG) is Possible, If Patient HasFrequent Complaint of Altered Visual Acuity (V.A) within Last 6 to 8 Months 如果患者在过去6 - 8个月内经常出现视力改变,则可以最早发现无症状青光眼(POAG)
Pub Date : 2018-10-31 DOI: 10.33140/jocr/02/03/00004
Purpose: To determine POAG in those patients have normal morphological fundi, C:D ratio and Neuroretinal rim, IOP may ormay not significant rised.Background: At first there are no detectable symptoms except history usually given by patients altered acuity and glasses are notworking properly, if this frequently complaint 3-4 times for last 8 months suspicion should developed for POAG.Design: Prospective Cohort study.Participant: Selection of Patients is based upon these factors:*Aged >40yrs regardless of gender discrimination.*Those have axial length of eye ball 24.0+/- 2.5mm.*Three or more consecutive visits to OPD for V.A correction within last 8 month.Method: We performed comphrensive Ophthalmic Examination i-e V.A, Ophthalmoscopy, Biomiroscopy, Gold standardApplanation Tonometry. When Patients have complaint persistant change of glasses without any defined morphology aetiology.We investigated these particular group for RNFL thinkness at OCT and measure thickness RNFL of twice in year.Result: There is variation of RNFL thickness in earliest suspected POAG patient with mean RNFL thickness 0.22 +/-0.1 moderatesuspected POAG mean RNFL thickness 0.16 +/-0.12 and with healthy patient mean RNFL thickness 0.23 +/-0.03. All have clinicalC:D ratio under range 0.2 to 0.5 and IOP under range of 14 to 18mmhg.Conclusion: We analysed the values thickness of RNFL at OCT along supportive history of frequent complaint altered V.A withinlast 8 months helps to sort out asymptomatic POAG before development of sign and symptoms associated with thousands of axonaldeath. Once Glaucoma developed, its hallmark of Irrveresible, Progressive, Permanent loss of vision badly affects quality of life.
目的:观察眼底形态、C:D比值和神经视网膜边缘正常的患者的POAG, IOP是否明显升高。背景:最初没有可检测到的症状,除了通常由患者的视力改变和眼镜不能正常工作的病史,如果这种频繁的抱怨在过去8个月3-4次,应考虑POAG。设计:前瞻性队列研究。参与者:患者的选择基于以下因素:*年龄bb0 - 40岁,不考虑性别歧视。*眼球轴向长度为24.0±2.5mm。*在过去8个月内,连续3次或以上到门诊求诊矫正静脉曲张。方法:采用眼内窥镜、眼内窥镜、生物显微镜、金标准眼压测量等方法进行综合眼科检查。当患者有主诉时,没有任何明确的形态和病因的持续性眼镜改变。我们在OCT上对这些特殊的人群进行了RNFL的厚度测量,并每年测量两次厚度RNFL。结果:早期疑似POAG患者的RNFL厚度存在差异,中度疑似POAG患者的RNFL平均厚度为0.22 +/-0.1,中度疑似POAG患者的RNFL平均厚度为0.16 +/-0.12,健康患者的RNFL平均厚度为0.23 +/-0.03。临床c:D比值均在0.2 ~ 0.5之间,IOP均在14 ~ 18mmhg之间。结论:我们分析了近8个月内频繁主诉的支持病史中RNFL厚度的价值,有助于在无症状POAG出现体征和症状之前对数千例轴索死亡进行分类。青光眼一旦发展,其标志是不可逆的、进行性的、永久性的视力丧失,严重影响生活质量。
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引用次数: 0
An Unusual Presentation of Horton’s Disease 霍顿病的一种不寻常的表现
Pub Date : 2018-10-11 DOI: 10.33140/jocr/02/03/00003
Horton’s disease or temporal giganto cellular arteritis is an inflammatory disease of the vessels, particularly affecting older female. We report the case of a 50-year-old patient with a classic clinical picture of anterior arteritic optic neuropathy with ischemia of the optic nerve, with a horizontal level and hypo-choroidal perfusion of the corresponding territory. The peculiarity in this patient is the negativity of the biological assessment and biopsy of the temporal artery
霍顿病或颞巨细胞动脉炎是一种血管炎症性疾病,尤其影响老年女性。我们报告了一例50岁的患者,其典型临床表现为前动脉性视神经病变伴视神经缺血,相应区域的水平和脉络膜灌注不足。这名患者的特点是颞动脉的生物评估和活检呈阴性
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引用次数: 0
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HSOA journal of ophthalmology & clinical research
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