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An Investigation of the Druid® Smartphone/Tablet App as a Rapid Screening Assessment for Cognitive and Psychomotor Impairment Associated with Alcohol Intoxication 德鲁伊®智能手机/平板电脑应用程序作为酒精中毒相关认知和精神运动障碍快速筛查评估的研究
Pub Date : 2019-03-29 DOI: 10.31707/vdr2019.5.1.p31
J. Richman, Lieutenant Stephen
BackgroundNeuropsychological tests have been used for years to determine impairments in cognitive and motor functions. There have been increases in impairment related to the abuse of alcohol and/or drugs related to driving. Recently, there has been an increased use of the Smartphone/Tablet applications for neurocognitive impairment testing. The DRUID® test is intended to identify and measure impairment from alcohol and various drugs by measuring changes in divided attention, decision making, reaction time, motor tracking, and balance movements control. We investigated the application of The DRUID® test as a potential rapid screening forcognitive and psychomotor impairment as a function of specific levels of alcohol that are known to have an effect on driving and job performance.MethodsThere were 48 volunteer drinkers, (Mean age 30[5.36])19 females -29 males who wereadministered a two minute DRUID® test pre and post drinking alcohol in a controlleddosage setting. Breath testing for alcohol was performed confirming absence of alcohol(Pre DRUDI®) and the when dosing exceeded the legal intoxication level for alcohol inMassachusetts (Blood Alcohol Content BAC 0.08%).ResultsDRUID® post drinking scores were significantly higher (worse) than DRUID® pre drinking. Higher scores on the BAC and DRUID® correspond to higher intoxicationand associated impairment. There were no significant differences by gender for any of the central variables. A repeated measures t-test comparing DRUID® pre and post alcohol BAC scores revealed a highly significant (t(47) = 34.5, p < .0001), difference in pre- and post DRUID® scores (t(47) = 8.68, p < .0001).Conclusions The DRUID® test is a compelling and useful Smartphone/Tablet based candidate asa rapid screening test for identifying cognitive and psychomotor impairment associated with the intoxication level of alcohol and effects on driving.
多年来,神经心理学测试一直被用来确定认知和运动功能的损伤。与驾驶相关的酒精和/或药物滥用有关的损害有所增加。最近,越来越多的人使用智能手机/平板电脑应用程序进行神经认知障碍测试。DRUID®测试旨在通过测量分散注意力、决策、反应时间、运动跟踪和平衡运动控制的变化来识别和测量酒精和各种药物的损害。我们研究了DRUID®测试的应用,作为认知和精神运动障碍的潜在快速筛查,作为特定酒精水平的功能,已知对驾驶和工作表现有影响。方法48名饮酒者志愿者(平均年龄30岁[5.36]),19名女性-29名男性,在控制剂量的情况下,在饮酒前后进行2分钟的DRUID®测试。进行酒精呼气测试,确认没有酒精(Pre DRUDI®),以及当剂量超过马萨诸塞州酒精的法定中毒水平(血液酒精含量BAC 0.08%)时。结果德鲁伊®饮酒后评分明显高于(低于)饮酒前评分。BAC和DRUID的分数越高,中毒和相关损伤就越严重。任何中心变量的性别差异都不显著。重复测量t检验比较DRUID®前后酒精BAC评分显示高度显著(t(47) = 34.5, p < 0.0001),德鲁id®前后评分差异(t(47) = 8.68, p < 0.0001)。DRUID®测试是一种令人信服且有用的基于智能手机/平板电脑的候选快速筛选测试,用于识别与酒精中毒水平和驾驶影响相关的认知和精神运动障碍。
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引用次数: 10
Exploring the Role of Telemedicine in Low Vision Rehabilitation in Patients with Heredomacular Degeneration – A Novel Concept 探讨远程医疗在遗传性黄斑变性患者低视力康复中的作用-一个新概念
Pub Date : 2019-03-29 DOI: 10.31707/vdr2019.5.1.p43
D. Ratra, Archayeeta Rakshit, V. Ratra
BackgroundTeleophthalmology is widely used for screening and diagnosis of many eye disorders. But its role in low vision rehabilitation is unexplored. The purpose of this study was to explore the feasibility of teleophthalmology for visual rehabilitation.MethodsWe prospectively enrolled 15 patients (age range 12-30 years, mean 16±3.2 years) withheredomacular degeneration with reduced central vision but healthy paracentral retina.We used visual stimulation and biofeedback with video game play. After the baselineinvestigations, the patients were given a compact disc with the video game and weretrained to play the game. Subsequently, they did 40 hours of the visual training at homewhich was monitored using teleophthalmology by us at our tertiary institute. We used video chat and screen sharing software to guide the patients and monitor compliance. The primary outcome was feasibility of monitoring visual training remotely and secondary outcome was improvement in visual function.ResultsSeven patients returned for follow up after completing the training. The visual acuityimproved from 0.74±0.29 to 0.66±0.32 logMAR (p=0.043). There was significant improvement in contrast sensitivity (p=0.023) and fixation stability (p=0.018). The vision related quality of life questionnaire showed improved scores. The ease of communication, patient comfort were high. The office visits were limited to two.Conclusions Our study showed preliminary evidence of benefit of teleophthalmology in visualrehabilitation and monitoring. The reduced visits would likely promote compliance andreduce economic burden of the rehabilitatory training.
远距眼医学广泛应用于多种眼部疾病的筛查和诊断。但它在低视力康复中的作用尚未被探索。本研究的目的是探讨远距眼科治疗视力康复的可行性。方法前瞻性纳入15例遗传性黄斑变性伴中央视力下降但中心旁视网膜健康的患者(年龄12-30岁,平均16±3.2岁)。我们在玩电子游戏时使用了视觉刺激和生物反馈。在基线调查之后,给患者一张装有视频游戏的光盘,并训练他们玩游戏。随后,他们在家进行了40小时的视力训练,由我们在我们的高等学院使用远距眼科学进行监测。我们使用视频聊天和屏幕共享软件来指导患者并监测依从性。主要结果是远程监控视觉训练的可行性,次要结果是视觉功能的改善。结果7例患者完成训练后返回医院接受随访。视力由0.74±0.29 logMAR改善至0.66±0.32 logMAR (p=0.043)。对比敏感度(p=0.023)和固定稳定性(p=0.018)均有显著提高。视力相关生活质量问卷得分有所提高。沟通方便,患者舒适度高。参观办公室的次数限制为两次。结论本研究初步证明了眼远距技术在视力康复和监测中的益处。减少访问次数可能会提高依从性并减轻康复训练的经济负担。
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引用次数: 0
A Phenotypically Variable Presentation of Albinism: A Case Report 白化病的表型可变表现:一例报告
Pub Date : 2019-01-01 DOI: 10.31707/vdr2019.5.2.p119
Nancy Sorrell, S. Schmiedecke, Kara Tison
Background: Albinism refers to a group of hereditary conditions, present at birth, that are characterized by gene mutations resulting in hypopigmentation of the skin, hair, and ocular structures. There are two categories of albinism distinguished by the mode of inheritance as well as the body structures affected: Oculocutaneous Albinism and Ocular Albinism. Case Report A 10 year old Caucasian-Hispanic female was referred to the Low Vision Clinic withvision impairment secondary to albinism, a diagnosis confirmed by the Electrophysiology Department two years prior. Ancillary testing supporting albinism included Visual Evoked Potentials (VEPs) demonstrating abnormal optic nerve fiber decussation and optical coherence tomography (OCT) revealing foveal hypoplasia. Clinical findings consistent with albinism included strabismus with reduced stereopsis, mild but diffuse iris transillumination defects and blonde fundi. The patient had physical characteristics of fair skin, light brown hair, and had normal color vision, moderately reduced visual acuity, and absence of nystagmus, suggesting a mild phenotypic variation of albinism. At her low vision evaluation, the patient appreciated improvement in visual function with the following devices: a dome magnifier for magnification at near, a handheld telescope for magnification at distance, and a light grey tint to reduce photophobia indoors. Additional accommodations were recommended to the school system to employ while in the classroom setting. Conclusion: Clinicians should consider the diagnosis of albinism in patients with reduced vision even when they demonstrate mostly normal skin and ocular pigmentation. Clinical cases associated with a better acuity in albinism patients include some presence of stereoacuity, mild strabismus, absence of nystagmus and near normal levels of iris pigmentation, like the patient described in the case report. Despite the level of visual impairment, the standard of care for patients with decreased vision or visual symptoms should always be a low vision evaluation in order to maximize functional vision.
背景:白化病是指一组出生时就存在的遗传性疾病,其特征是基因突变导致皮肤、头发和眼部结构的色素沉着降低。根据遗传方式和受影响的身体结构,白化病分为两类:眼皮肤白化病和眼白化病。病例报告:一名10岁的白人西班牙裔女性因继发于白化病的视力损害被转介到低视力诊所,两年前经电生理科确诊。支持白化病的辅助检查包括视觉诱发电位(vep)显示异常的视神经纤维讨论和光学相干脑电图(OCT)显示中央凹发育不全。临床表现与白化病一致,包括斜视伴立体视功能降低,轻度但弥漫性虹膜透光缺损和眼底金色。患者皮肤白皙,头发浅棕色,色觉正常,视力中度下降,无眼球震颤,提示白化病轻度表型变异。在她的低视力评估中,患者通过以下设备改善了视觉功能:近距离放大的多倍放大镜,远距离放大的手持望远镜,以及减少畏光的浅灰色色调。在课堂环境中,向学校系统推荐了额外的住宿。结论:临床医生应考虑白化病的诊断患者视力下降,即使他们表现出大部分正常的皮肤和眼部色素沉着。与较好的视力相关的白化病患者的临床病例包括一些立体视敏、轻度斜视、无眼球震颤和接近正常水平的虹膜色素沉着,如病例报告中描述的患者。尽管视力受损程度不同,但对于视力下降或有视力症状的患者,护理标准应该始终是低视力评估,以最大限度地提高功能性视力。
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引用次数: 0
Binocular and Monocular Coincidence-Anticipation Timing Responses 双眼和单眼重合-预期时间反应
Pub Date : 2018-12-20 DOI: 10.31707/vdr2018.4.4.p186
BackgroundCoincidence-anticipation timing (CAT) responses require individuals to determine the time at which an approaching object will arrive at (time to collision) or pass by (time to passage) the observer and to then make a response coincident with this time. Previous studies suggest that under some conditions time to collision estimates are more accurate when binocular and monocular cues are combined. The purpose of this study was to compare binocular and monocular coincidence anticipation timing responses with the Bassin Anticipation Timer, a device for testing and training CAT responses.Methods: Useable data were obtained from 20 participants. Coincidence-anticipation timing responses were determined using a Bassin Anticipation Timer over a range of approaching stimulus linear velocities of 5 to 40mph. Participants stood to the left side of the Bassin Anticipation track. The track was below eye height. The participants’ task was to push a button to coincide with arrival of the approaching stimulus at a location immediately adjacent to the participant. CAT responses were made under three randomized conditions: binocular viewing, monocular dominant eye viewing, andmonocular non-dominant eye viewing.Results: Signed (constant), unsigned (absolute), and variable (standard deviation) CAT response errors were determined and compared across viewing conditions at eachstimulus velocity. There were no significant differences in CAT errors between theconditions at any stimulus velocity, although the differences in signed and unsignederrors approached significance at 40mph. Conclusions: The addition of binocular cues did not result in a reduction in coincidence anticipation timing response errors compared to the monocular viewing conditions. There were no differences in CAT response errors between the monocular dominant eye viewing and monocular non-dominant eye viewing conditions.
背景巧合-预期时间(CAT)反应要求个体确定接近的物体到达(碰撞时间)或经过(通过时间)观察者的时间,然后做出与此时间一致的反应。先前的研究表明,在某些情况下,当双眼和单眼线索结合在一起时,对碰撞时间的估计更准确。本研究的目的是比较双眼和单眼的巧合预期时间反应与Bassin预期计时器,一个测试和训练CAT反应的装置。方法:从20名参与者中获得可用资料。在接近5到40英里/小时的刺激线速度范围内,使用Bassin预期计时器来确定巧合-预期计时反应。参与者站在Bassin expectations赛道的左侧。铁轨在视线高度以下。参与者的任务是按下一个按钮,以配合即将到来的刺激到达参与者旁边的位置。在三种随机条件下进行CAT反应:双眼观看、单目优势眼观看和单目非优势眼观看。结果:在不同的观看条件下,确定并比较了有符号(常数)、无符号(绝对)和可变(标准偏差)CAT响应误差。在任何刺激速度下,不同条件下的CAT误差没有显著差异,尽管在40英里/小时时,有符号和无符号误差的差异接近显著。结论:与单眼观察条件相比,双眼提示的增加并没有导致重合预期时间反应误差的减少。在单目优势眼和单目非优势眼观察条件下,CAT反应误差没有差异。
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引用次数: 3
Screen Time in the Pediatric Population: A Review of Its Effects on Refractive Error, Attention and Learning, and Ocular Health 儿童人群的屏幕时间:对屈光不正、注意力和学习以及眼部健康影响的综述
Pub Date : 2018-09-24 DOI: 10.31707/vdr2018.4.3.p128
Executive Summary“Screen time” has become a topic of discussion amongst the scientific and medicalcommunities in recent years with the marked increase of electronic devices in Americanhomes. Electronic devices have not only become commonplace for the average adultboth in the workplace and recreation, but they have also become a staple in the lives ofchildren in communication with friends/family, education, and recreation. In optometry, this has led to many questions pertaining to the manner in which these devices affect a child’s development of refractive error, attention and learning skills, and ocular health. This review article summarizes some of the most recent research in the area of screen time as it pertains to the practicing optometrist examining children, offering recommendations on how to manage these patients and educate their parents on this current issue.
近年来,随着美国家庭中电子设备的显著增加,“屏幕时间”已成为科学界和医学界讨论的一个话题。电子设备不仅在工作场所和娱乐场所对普通成年人来说都是司空见惯的,而且它们也成为孩子们与朋友/家人交流、教育和娱乐的生活必需品。在验光方面,这导致了许多与这些设备影响儿童屈光不正、注意力和学习技能以及眼部健康的方式有关的问题。这篇综述文章总结了一些最近在屏幕时间领域的研究,因为它与验光师检查儿童有关,并就如何管理这些患者和教育他们的父母提出了建议。
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引用次数: 0
Divided Visual Attention Performance of Ice Hockey Players with History of Concussion 有脑震荡病史的冰球运动员的分散视觉注意表现
Pub Date : 2018-09-24 DOI: 10.31707/vdr2018.4.3.p121
Background: A significant part of successful athletic performance is the use of peripheral vision. A divide visual attention task with a central and peripheral target was used to assess athletes with and without a history of concussion. The research suggests that both groups had the same response accuracy in the task performance. The purpose of this research was to determine if peripheral visual attention is impacted in ice hockey players who have had a history of one or more self reported concussion.Methods: Orientation discrimination accuracy of a pair of Landolt type block “C” targets was measured using a divided covert attention task on 22 collegiate level men’s ice hockey players. Stimuli were presented simultaneously at central fixation and at one of 40 peripheral locations against a bright white background for two stimulus durations (150ms and 15ms). Block “C” targets were presented at one of 4 orientations (up, down, left and right) and randomized for central and peripheral locations.Results: Overall there was a statistically significant difference in the performance at150ms and 15ms stimuli durations; athletes had a larger area of correct responses with the 150ms stimulus duration. Athletes performed better in the horizontal meridian compared to the vertical meridian for both stimulus durations.Conclusion: The divided visual attention test results for a cohort of university level men’sice hockey players shows a decline in area of correct responses with shorter stimulusdurations. There was no difference in response accuracy between those with a history of a concussion compared to those without a previous concussion.
背景:成功的运动表现的一个重要部分是使用周边视觉。采用中央和周围目标分割视觉注意任务来评估有和没有脑震荡史的运动员。研究表明,两组人在任务执行中的反应准确性是相同的。本研究的目的是确定有过一次或多次自我报告的脑震荡史的冰球运动员的周边视觉注意力是否受到影响。方法:以22名大学生冰球运动员为研究对象,采用分隐注意任务对Landolt类型block“C”目标的定向识别精度进行测量。在明亮的白色背景下,在中央固定和40个外围位置中的一个同时呈现刺激,刺激持续时间为150ms和15ms。Block“C”靶以4种方向(上、下、左、右)中的一种呈现,并随机选择中心和外围位置。结果:总体而言,150ms和15ms刺激时的表现差异有统计学意义;当刺激持续时间为150ms时,运动员的正确反应面积较大。在两种刺激持续时间下,运动员在水平子午线上的表现比在垂直子午线上的表现更好。结论:大学水平男子冰球运动员的分割视觉注意测试结果显示,较短的刺激使正确反应面积下降。有脑震荡史的人与没有脑震荡史的人相比,在反应准确性上没有差异。
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引用次数: 1
Providing Care of Mild Traumatic Brain Injury by the Family Practice/Primary Care Optometrist 由家庭执业/初级保健验光师提供轻度创伤性脑损伤的护理
Pub Date : 2018-09-24 DOI: 10.31707/vdr2018.4.3.p110
Primary Objectives: By extending the scope of knowledge of the primary care optometrist, the brain injury population will have expanded access to entry level neurooptometric care by optometric providers who have a basic understanding of their neurovisual problems, be able to provide some treatment and know when to refer to their colleagues who have advanced training in neuro-optometric rehabilitation.
主要目标:通过扩大初级保健验光师的知识范围,脑损伤人群将扩大获得初级神经验光护理的机会,验光师对他们的神经视觉问题有基本的了解,能够提供一些治疗,并知道何时向接受过高级神经验光康复培训的同事求助。
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引用次数: 1
Case Report: Management of a Patient with mTBI and Vestibular Hypofunction with the Binasal Occlusion Technique 病例报告:应用双鼻闭塞技术治疗mTBI合并前庭功能障碍1例
Pub Date : 2018-06-27 DOI: 10.31707/vdr2018.4.2.p87
Background: Binasal Occlusion (BNO) is a clinical technique used by many neurorehabilitative optometrists in patients with mild traumatic brain injury (mTBI) andincreased visual motion sensitivity (VMS) or visual vertigo. BNO is a technique in whichpartial occluders are added to the spectacle lenses to suppress the abnormal peripheral visual motion information. This technique helps in reducing VMS symptoms (i.e., nausea, dizziness, balance difficulty, visual confusion). Case Report: A 44-year-old AA female presented for a routine eye exam with a historyof mTBI approximately 33 years ago. She was suffering from severe dizziness for the last two years that was adversely impacting her ADLs. The dizziness occurred in all body positions and all environments throughout the day. She was diagnosed with vestibular hypofunction and had undergone vestibular therapy but reported little improvement. Neurological exam revealed dizziness with both OKN drum and hand movement, especially in the left visual field. BNO technique resulted in immediate relief of her dizziness symptoms. Conclusion: To our knowledge, this is the first case that illustrates how the BNO technique in isolation can be beneficial for patients with mTBI and vestibular hypofunction. It demonstrates the success that BNO has in filtering abnormal peripheral visual motion in these patients.
背景:鼻闭锁(BNO)是许多神经康复视光师在轻度创伤性脑损伤(mTBI)和视觉运动敏感性(VMS)增加或视觉眩晕患者中使用的一种临床技术。BNO是一种在镜片上添加部分遮挡物来抑制异常周边视觉运动信息的技术。这项技术有助于减轻VMS症状(如恶心、头晕、平衡困难、视觉混乱)。病例报告:一名44岁AA女性,约33年前有mTBI病史,前来例行眼科检查。在过去的两年里,她一直患有严重的头晕,这对她的adl产生了不利影响。眩晕发生在全天所有体位和所有环境中。她被诊断为前庭功能减退,并接受了前庭治疗,但收效甚微。神经学检查显示OKN鼓和手运动伴有头晕,尤其是在左视野。BNO技术立即缓解了她的头晕症状。结论:据我们所知,这是第一例单独的BNO技术对mTBI和前庭功能减退患者有益的病例。这表明BNO在滤除这些患者的外周视觉运动异常方面取得了成功。
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引用次数: 0
Clinical Evaluation of the MKH-HAASE Stereoacuity Tests MKH-HAASE立体视力试验的临床评价
Pub Date : 2018-06-27 DOI: 10.31707/vdr2018.4.2.p78
Background: H.J. Haase developed a set of tests for measuring associated phoria andstereopsis using a variety of different targets for each. This study investigates the test-retest repeatability of the distance and near stereopsis tests for the MKH-Haase charts.Methods: MKH-Haase contour (Line Test) and randomdot (Steps Test) stereopsistests were measured at distance and near for 34 symptomatic and 40 asymptomaticparticipants on two different sessions. The MKH-Haase protocol requires the stereoacuity to be measured twice within a session; once for crossed and once for uncrossed disparities. Results: Direct comparison within sessions did not reveal any significant differences in MKHHaase stereoacuity tests between symptomatic and asymptomatic groups; hence, the two groups were pooled for further analysis. The within and between-sessions repeatability of most MKH-Haase stereoacuity tests results was good at both distance and near. However, there were a few exceptions to this general finding. Crossed disparity thresholds were significantly lower than uncrossed disparities within the first session at distance for both Line and Steps tests. The differences between sessions for both disparities were not significant for all stereoacuity tests except the Steps test at distance.Conclusions: MKH-Haase stereoacuity charts are considered reliable tests for measuring local and global stereothreshold at both distance and near.
背景:H.J. Haase开发了一套测试来测量相关的斜视和立体视,使用各种不同的目标。本研究探讨了MKH-Haase图的距离和近立体视测试的重测重复性。方法:对34例有症状者和40例无症状者在两个不同的时段进行远距离和近距离立体抵抗测试。MKH-Haase协议要求在一次测试中测量两次立体视敏度;一次是交叉的,一次是未交叉的。结果:疗程内的直接比较未显示有症状组和无症状组的MKHHaase立体视力测试有任何显著差异;因此,将两组合并进行进一步分析。大多数MKH-Haase立体视力测试结果在远距离和近距离上的重复性都很好。然而,这一普遍发现也有一些例外。在直线和步骤测试中,交叉差异阈值在距离上显著低于未交叉差异阈值。除了距离上的Steps测试外,两种差异在所有立体敏锐度测试中的差异都不显著。结论:MKH-Haase立体视敏度图被认为是在远近距离测量局部和全局立体阈值的可靠测试。
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引用次数: 2
Basic Neuro-Optometric Diagnostic Tests for Mild Traumatic Brain Injury/Concussion: A Narrative Review, Perspective, Proposed Techniques and Protocols 轻度创伤性脑损伤/脑震荡的基本神经验光诊断测试:叙述回顾,观点,建议的技术和方案
Pub Date : 2018-01-01 DOI: 10.31707/vdr2018.4.4.p157
K. Ciuffreda, B. Tannen, D. Ludlam
Vision problems are common in individuals with mild traumatic brain injury (mTBI)/concussion. However, a global conceptualization of the diagnostic process remains incomplete and practitioner dependent. Thus, a comprehensive diagnostic test battery is proposed to assist in the management of these patients. This battery includes a range of basic clinical tests of a sensory and motor nature, with all having a clinical and scientific rationale. These tests have been used by the authors for many years, with good success, and furthermore they have been found to be clinically useful and insightful.
视力问题在轻度创伤性脑损伤(mTBI)/脑震荡患者中很常见。然而,诊断过程的全球概念化仍然不完整,并且依赖于医生。因此,提出了一种全面的诊断测试电池,以协助这些患者的管理。这套系统包括一系列感觉和运动性质的基本临床测试,所有这些测试都有临床和科学依据。这些测试已被作者使用多年,取得了良好的成功,而且它们已被发现是临床上有用的和有见地的。
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引用次数: 2
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Vision development and rehabilitation
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