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Convergence Insufficiency Treatment Trial - Attention and Reading Trial (CITT-ART): Design and Methods. 收敛功能不全治疗试验-注意力和阅读试验(CITT-ART):设计和方法。
Pub Date : 2015-10-01 DOI: 10.31707/vdr2015.1.3.p214
M. Scheiman, G. Mitchell, S. Cotter, M. Kulp, C. Chase, E. Borsting, Eugene Arnold, Carolyn A. Denton, R. Hertle
OBJECTIVETo describe the design and methodology of the Convergence Insufficiency Treatment Trial: Attention and Reading Trial (CITT-ART), the first randomized clinical trial evaluating the effect of vision therapy on reading and attention in school-age children with symptomatic convergence insufficiency (CI).METHODSCITT-ART is a multicenter, placebo-controlled, randomized clinical trial of 324 children ages 9 to 14 years in grades 3 to 8 with symptomatic CI. Participants are randomized to 16 weeks of office-based vergence/accommodative therapy (OBVAT) or placebo therapy (OBPT), both supplemented with home therapy. The primary outcome measure is the change in the Wechsler Individual Achievement Test-Version 3 (WIAT-III) reading comprehension subtest score. Secondary outcome measures are changes in attention as measured by the Strengths and Weaknesses of Attention (SWAN) as reported by parents and teachers, tests of binocular visual function, and other measures of reading and attention. The long-term effects of treatment are assessed 1 year after treatment completion. All analyses will test the null hypothesis of no difference in outcomes between the two treatment groups. The study is entering its second year of recruitment. The final results will contribute to a better understanding of the relationship between the treatment of symptomatic CI and its effect on reading and attention.CONCLUSIONThe study will provide an evidence base to help parents, eye professionals, educators, and other health care providers make informed decisions as they care for children with CI and reading and attention problems. Results may also generate additional hypothesis and guide the development of other scientific investigations of the relationships between visual disorders and other developmental disorders in children.
目的描述会聚功能不全治疗试验的设计和方法:注意和阅读试验(CITT-ART),这是第一个评估视力治疗对症状性会聚功能不全(CI)学龄儿童阅读和注意力影响的随机临床试验。方法scitt - art是一项多中心、安慰剂对照、随机临床试验,纳入324名年龄在9至14岁、3至8年级、有症状CI的儿童。参与者被随机分配到16周的以办公室为基础的融合/调节治疗(OBVAT)或安慰剂治疗(OBPT),两者都辅以家庭治疗。主要的结果测量是韦氏个人成就测试版本3 (WIAT-III)阅读理解子测试分数的变化。次要结果测量是由家长和老师报告的注意力优势和弱点(SWAN)测量的注意力变化,双眼视觉功能测试,以及其他阅读和注意力测量。治疗结束后1年评估治疗的长期效果。所有的分析都将检验两个治疗组之间结果无差异的原假设。该研究已进入第二年招募阶段。最终的结果将有助于更好地理解症状性脑损伤的治疗与其对阅读和注意力的影响之间的关系。结论:该研究将为父母、眼科专业人士、教育工作者和其他卫生保健提供者提供证据基础,帮助他们在照顾有CI、阅读和注意力问题的儿童时做出明智的决定。研究结果还可能产生额外的假设,并指导其他儿童视觉障碍与其他发育障碍之间关系的科学研究的发展。
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引用次数: 29
Fall Avoidance: Motion Parallax Cues and Balance Control Therapy 避免跌倒:运动视差提示和平衡控制疗法
Pub Date : 1900-01-01 DOI: 10.31707/vdr2021.7.1.p35
Background: Apart from vision correction, there appears to be a need for a method of increasing the success of balance exercises by using more sensitive methods of detecting postural sway. Methods: Reference to relevant articles from a wide range of sources were used to examine how the well-established theoretical basis for motion parallax phenomena, and the examples of rifle and pistol shooting, can be used to explain the practical application of those principles to balance exercises. Results: An approach to balance enhancement exercises has been developed and a step by step set of instructions have been prepared that enable fall-risk patients to make motion parallax observations which detect small degrees of postural sway, and so allow for appropriate minor corrections to be achieved so that balance is maintained. Conclusions: These instructions provide a mechanism whereby balance can be maintained during balance improvement exercises with associated reduced need for major postural sway corrections which would otherwise risk over-correction and loss of balance. Improved performance during balance exercises may have the potential to promote the development and consolidation of the sensory integration required for maintaining balance outside the remedial balance exercise setting. Apart from helping to build confidence during a variety of balance exercises, these methods of balance control also appear to have relevance as supportive adjuncts to some strength and endurance exercises which are used to improve balance maintenance.
背景:除了视力矫正外,似乎还需要一种方法,通过使用更灵敏的检测姿势摇摆的方法来增加平衡练习的成功率。方法:广泛查阅相关文献,探讨运动视差现象的理论基础,并以步枪和手枪射击为例,解释运动视差原理在平衡练习中的实际应用。结果:一种平衡增强练习的方法已经开发出来,一步一步的指导集已经准备好了,使跌倒风险患者能够进行运动视差观察,检测小程度的姿势摇摆,从而允许适当的轻微纠正,以保持平衡。结论:这些指导提供了一种机制,在平衡改善练习中可以保持平衡,同时减少了对主要姿势摆动纠正的需求,否则会有过度纠正和失去平衡的风险。在平衡练习中提高表现可能有潜力促进在补救性平衡练习之外维持平衡所需的感觉统合的发展和巩固。除了在各种平衡练习中帮助建立信心外,这些平衡控制方法似乎也与一些用于改善平衡维持的力量和耐力练习有相关性。
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引用次数: 0
Assessment of Three Clinical Tests for Evaluation of Concussion/Mild Traumatic Brain Injury 三种评估脑震荡/轻度创伤性脑损伤的临床试验的评价
Pub Date : 1900-01-01 DOI: 10.31707/vdr2021.7.1.p43
A focus of both basic and clinical research on concussion/mild traumatic brain injury has been to ascertain which test, or combination of tests, is best for its detection. In the present retrospective analysis, three potential clinical tests were evaluated to determine which one, or combination, best differentiated between visually-symptomatic concussed (n=52) versus asymptomatic non-concussed (n=24) patients. The three tests were: distance horizontal vergence facility, peripheral visual motion, and critical flicker fusion. Each test was found to differentiate the two groups. The peripheral visual motion test was the best, with a sensitivity of 93.8% and a specificity of 83.3%. When this test was combined with the distance horizontal vergence facility test, specificity remained the same whereas sensitivity increased to 94.4%. Addition of the critical flicker fusion test did not affect these values. Thus, of the three, the combination of the peripheral visual motion and distance horizontal vergence facility tests has a high probability of assisting in concussion detection and diagnosis.
脑震荡/轻度创伤性脑损伤的基础研究和临床研究的一个重点是确定哪种测试或哪种测试组合最适合检测。在本回顾性分析中,评估了三种潜在的临床试验,以确定哪一种或哪一种组合能最好地区分有视觉症状的脑震荡(n=52)和无症状的非脑震荡(n=24)患者。三项测试分别是:距离水平汇聚、周边视觉运动和临界闪烁融合。每个测试都能区分两组。外周视觉运动检查的灵敏度为93.8%,特异性为83.3%。结合距离水平辐合设施检测,特异度保持不变,敏感性提高至94.4%。增加临界闪烁融合试验对这些值没有影响。因此,在这三者中,结合周边视觉运动和距离水平辐合设施测试有很高的可能性有助于脑震荡的检测和诊断。
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引用次数: 1
Some Thoughts on Clinical Eye Movement Testing 对临床眼动测试的几点思考
Pub Date : 1900-01-01 DOI: 10.31707/vdr2021.7.1.p7
Assessment of eye movements is one of the most important procedures in the optometric armamentarium. Since abnormal eye movements are found in a wide range of vision-based (e.g., amblyopia) and non-vision-based (e.g., multiple sclerosis) diagnoses, which in many cases are remediable, it is crucial that they be tested in a careful, informative manner, with their functional consequences considered. In this paper, some of our thoughts on this important clinical process are presented.
眼动评估是验光院里最重要的程序之一。由于异常眼动在很多基于视力的诊断(如弱视)和非基于视力的诊断(如多发性硬化症)中都有发现,而这些诊断在许多情况下是可以补救的,因此以仔细、翔实的方式进行检测是至关重要的,并考虑到它们的功能后果。在本文中,我们对这一重要的临床过程提出了一些想法。
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引用次数: 0
Introduction of a New Test for Standardizing and Quantifying Monocular Fixation: The Aalen-Pacific Fixation Accuracy & Stability Test (AP-FAST) 单眼固定标准化和定量化新方法:aallen - pacific固定精度和稳定性试验(AP-FAST)
Pub Date : 1900-01-01 DOI: 10.31707/vdr2021.7.1.p17
Background: This is a two-part paper, in which fixational eye movements are reviewed in part one, and a new clinical test of fixational eye movement accuracy and stability is introduced in part two. Part two also contains a partial validation study and normative results for this new test. The study was designed to explore the following questions: 1. Is there a significant difference in clinically measurable fixation stability and accuracy between symptomatic individuals who have sustained mTBI versus visually normal individuals who have not sustained TBI? 2a. Could the Macular Integrity Tester (MIT) be useful as a diagnostic instrument for differentiating fixation stability and accuracy with mTBI patients versus those without TBI? 2b. If so, could introduction of a standardized test protocol (AP-FAST) allow for more reliable and descriptive quantification of monocular fixation behavior? Methods: To answer the first question posed in our study, data were compared between non-mTBIs and mTBI patients using two different fixation testing methods. One of the methods employed the eyetracker EyeLink II comparing optometry students to mTBI patients. Fixation accuracy and stability were measured with a custom fixation pattern program. Fixation results were compared for both groups. To answer question 2a, we compared fixation behavior for both groups using the MIT diagnostically by having each subject rate accuracy and stability of his/her own fixation posture. To address question 2b, a 15-point rating system protocol was created to help describe and quantify monocular fixation behavior via Haidinger’s brush perception. Two groups of test subjects: mTBI patients versus visually normal subjects were compared using the AP-FAST grid and fixation behavior survey. Results: Regarding question one, there was a significant and clinically relevant difference in monocular fixation stability and accuracy between the visual normal subject group and mTBI patient group, with normals demonstrating better accuracy and stability. Regarding questions 2a and 2b, the mTBI patient group had poorer mean ability (statistically significant) to perceive, localize, and center the Haidinger’s brush than those in the non-TBI group. Based on our results, we propose that the newly developed AP-FAST is useful for helping describe, standardize and quantify how the Haidinger’s brush entoptic phenomenon is perceived monocularly by both mTBI and nonmTBI subjects.
背景:这是一篇两部分的论文,第一部分回顾了眼球固定运动,第二部分介绍了一种新的眼球固定运动准确性和稳定性的临床测试方法。第二部分还包含了这个新测试的部分验证研究和规范结果。本研究旨在探讨以下问题:1。有症状的持续性mTBI患者与没有持续性TBI的视力正常患者在临床可测量的固定稳定性和准确性方面是否存在显著差异?黄斑完整性测试仪(MIT)是否可以作为区分mTBI患者与非TBI患者固定稳定性和准确性的诊断工具?如果是这样的话,标准化测试方案(AP-FAST)的引入是否可以对单目注视行为进行更可靠和描述性的量化?方法:为了回答我们研究中提出的第一个问题,我们使用两种不同的固定测试方法比较了非mTBI和mTBI患者的数据。其中一种方法是使用眼动仪EyeLink II来比较验光学生和mTBI患者。采用定制固定模式程序测量固定精度和稳定性。比较两组固定结果。为了回答问题2a,我们使用MIT诊断来比较两组的固定行为,让每个受试者评估他/她自己固定姿势的准确性和稳定性。为了解决问题2b,我们创建了一个15分的评分系统协议,以帮助描述和量化通过海丁格的画笔感知的单目注视行为。两组测试对象:mTBI患者和视力正常的受试者使用AP-FAST网格和注视行为调查进行比较。结果:关于问题一,视力正常受试者组与mTBI患者组在单眼固定的稳定性和准确性上存在显著且具有临床意义的差异,正常受试者的精确度和稳定性更好。关于问题2a和2b, mTBI患者组感知、定位和居中的平均能力比非tbi组差(有统计学意义)。基于我们的研究结果,我们提出新开发的AP-FAST有助于描述、标准化和量化mTBI和非mTBI受试者如何感知海丁格刷全视现象。
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引用次数: 0
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Vision development and rehabilitation
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