Pub Date : 2023-11-14DOI: 10.1080/09291016.2023.2283656
Csenge G. Horváth, Róbert Bódizs
{"title":"Association of actigraphy-derived circadian phase indicators with the nadir of spindle frequency","authors":"Csenge G. Horváth, Róbert Bódizs","doi":"10.1080/09291016.2023.2283656","DOIUrl":"https://doi.org/10.1080/09291016.2023.2283656","url":null,"abstract":"","PeriodicalId":9208,"journal":{"name":"Biological Rhythm Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134993009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACT Seasonal variations in semen parameters play a critical role in the reproductive efficiency and fertility of domestic animals. Factors such as temperature, photoperiod, and humidity directly impact sperm concentration, viability, motility, morphology, seminal plasma composition, and other semen parameters. Understanding these seasonal variations in semen parameters is crucial for optimising reproductive management practices in domestic animal populations. This comprehensive review provides valuable insights for improving breeding programs, artificial insemination techniques, and overall reproductive management in domestic animals.
{"title":"Seasonal changes in semen parameters of domestic animals: an overview","authors":"Prasanna Pal, Fanny Josan, Sonam Yadav, Sonika Grewal","doi":"10.1080/09291016.2023.2273888","DOIUrl":"https://doi.org/10.1080/09291016.2023.2273888","url":null,"abstract":"ABSTRACT Seasonal variations in semen parameters play a critical role in the reproductive efficiency and fertility of domestic animals. Factors such as temperature, photoperiod, and humidity directly impact sperm concentration, viability, motility, morphology, seminal plasma composition, and other semen parameters. Understanding these seasonal variations in semen parameters is crucial for optimising reproductive management practices in domestic animal populations. This comprehensive review provides valuable insights for improving breeding programs, artificial insemination techniques, and overall reproductive management in domestic animals.","PeriodicalId":9208,"journal":{"name":"Biological Rhythm Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136104152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACTThis study aims to assess the chrononutrition behaviors, circadian parameters, and meal distribution of the dietary intake according to the chronotypes. This study included 362 adults (51.1% females and 48.9% males). 24-hour dietary recalls were performed separately for weekdays and weekends. Chrono nutritional behaviours, the Night Eating Questionnaire, Pittsburg’s Sleep Quality Index and the Morningness-Eveningness Questionnaire were performed. Morning individuals were found to have more regular meals, had a higher total number of meals and frequency of breakfast, while they had lower NES scores and eating jetlag than evening individuals. Breakfast energy intake was greater in the morning group on weekdays and weekends, whereas dinner energy intake was higher in the evening group only on weekdays.The evening chronotype has been reported to have more unhealthy eating habits and to be prone to having more energy intake in later hours. Further study is needed to recommed dietary treatment based on chronotype and chrononutrition for optimal health.KEYWORDS: Chrononutritionchronotypecircadian parametersdietary intakebreakfast AcknowledgmentsThe authors are grateful to all the individuals who contributed their time to this study. We appreciate their helpful and sincere cooperation as well as their enthusiastic support for the work.Disclosure statementNo potential conflict of interest was reported by the author(s).Credit authorship contribution statementGizem Özata-Uyar: Investigation, Data curation, Methodology, Formal Analysis, Writing – Original Draft, Writing- review & editingHilal Yıldıran: Supervision, Writing- review & editingGülay Korkmaz: Investigation, Data curation, MethodologyGülnur Kılıç: Investigation, Data curation, MethodologyBehiye Nur Korkmaz: Investigation, Data curation, MethodologyAdditional informationFundingThis research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
摘要本研究旨在探讨不同时型动物的时间营养行为、昼夜节律参数及膳食摄入的膳食分布。本研究包括362名成年人(51.1%为女性，48.9%为男性)。在工作日和周末分别进行24小时饮食回顾。进行时间营养行为、夜间进食问卷、匹兹堡睡眠质量指数和早晚性问卷调查。研究发现，早起的人吃饭更规律，总吃饭次数和早餐频率更高，而他们的NES得分和饮食时差都低于晚睡的人。在工作日和周末，早晨组的早餐能量摄入量更高，而晚上组的晚餐能量摄入量仅在工作日更高。据报道，晚睡型的人有更多不健康的饮食习惯，并且在晚些时候容易摄入更多的能量。需要进一步的研究来推荐基于时间类型和时间营养的最佳健康饮食治疗。关键词:时间营养、生物钟参数、饮食摄入、早餐感谢作者感谢所有为本研究贡献时间的个人。我们感谢他们的帮助和真诚的合作以及他们对工作的热情支持。披露声明作者未报告潜在的利益冲突。gizem Özata-Uyar:调查、数据策展、方法论、形式分析、写作-原稿、写作-审查与编辑hilal Yıldıran:监督、写作-审查与编辑 lay Korkmaz:调查、数据策展、方法论 lnur Kılıç:调查、数据策展、方法论behiye Nur Korkmaz:调查、数据管理、方法附加信息本研究未获得公共、商业或非营利部门资助机构的任何特定资助。
{"title":"The effect of chronotype on chrononutrition and circadian parameters in adults: a cross-sectional study","authors":"Gizem Özata Uyar, Hilal Yildiran, Gülay Korkmaz, Gülnur Kiliç, Behiye Nur Kesgin","doi":"10.1080/09291016.2023.2272764","DOIUrl":"https://doi.org/10.1080/09291016.2023.2272764","url":null,"abstract":"ABSTRACTThis study aims to assess the chrononutrition behaviors, circadian parameters, and meal distribution of the dietary intake according to the chronotypes. This study included 362 adults (51.1% females and 48.9% males). 24-hour dietary recalls were performed separately for weekdays and weekends. Chrono nutritional behaviours, the Night Eating Questionnaire, Pittsburg’s Sleep Quality Index and the Morningness-Eveningness Questionnaire were performed. Morning individuals were found to have more regular meals, had a higher total number of meals and frequency of breakfast, while they had lower NES scores and eating jetlag than evening individuals. Breakfast energy intake was greater in the morning group on weekdays and weekends, whereas dinner energy intake was higher in the evening group only on weekdays.The evening chronotype has been reported to have more unhealthy eating habits and to be prone to having more energy intake in later hours. Further study is needed to recommed dietary treatment based on chronotype and chrononutrition for optimal health.KEYWORDS: Chrononutritionchronotypecircadian parametersdietary intakebreakfast AcknowledgmentsThe authors are grateful to all the individuals who contributed their time to this study. We appreciate their helpful and sincere cooperation as well as their enthusiastic support for the work.Disclosure statementNo potential conflict of interest was reported by the author(s).Credit authorship contribution statementGizem Özata-Uyar: Investigation, Data curation, Methodology, Formal Analysis, Writing – Original Draft, Writing- review & editingHilal Yıldıran: Supervision, Writing- review & editingGülay Korkmaz: Investigation, Data curation, MethodologyGülnur Kılıç: Investigation, Data curation, MethodologyBehiye Nur Korkmaz: Investigation, Data curation, MethodologyAdditional informationFundingThis research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.","PeriodicalId":9208,"journal":{"name":"Biological Rhythm Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136261520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACTThe adaptive physiological functions of black Bengal goats (Capra hircus) of coastal regions were compared with goats from the plains during winter, spring, and summer seasons. Goats in the coastal zone had significantly (P < 0.01) higher plasma electrolytes levels. Goats in the plains zone had significantly (P < 0.01) higher haemoglobin, PCV, TEC, and erythrocyte indices and lower TLC values. Glucose, total protein, and creatinine were significantly (P < 0.01) lower, whereas cholesterol, BUN, and SGPT were significantly (P < 0.01) higher in goats of coastal zone. Regardless of zones, glucose, total protein, and creatinine levels were higher in winter, cholesterol and SGOT levels were higher in spring, and BUN was higher in summer. Goats from coastal areas had significantly (P < 0.05) higher urinary pH and urea levels. Goats in the coastal zone had significantly (P < 0.05) higher cortisol concentrations. From the above study, we can conclude that salinity of feed, soil and water does not significantly affect the homeostasis of black Bengal goats reared in coastal areas, indicating their adaptability to saline coastal environments and their potential for reproduction in a climate-resilient livestock system.HIGHLIGHTS The fodder, water and soil of coastal areas contain higher amounts of sodium, zinc, and iron in the compared to plain areas.Black Bengal goats raised in coastal regions are able to maintain their homeostasis without much altering hemato-biochemical and endocrine profiles.Black Bengal goats can be a good option for climate resilient animal husbandry system.KEYWORDS: Salinityblack Bengal goatsadaptationphysio-biochemicalendocrine AcknowledgmentsThe authors are thankful to the Vice-Chancellor, WBUAFS along with the All India Coordinated Research Project (AICRP, ICAR) on goats and ICAR-IVRI, ERS for providing necessary supports for this study.
{"title":"Adaptive changes of physiological functions and their seasonal variations in goats of coastal areas of Sundarban","authors":"Tripti Sharma, Joydip Mukherjee, Pradip Kumar Das, Probal Ranjan Ghosh, Kinsuk Das, Syamal Naskar, Santanu Bera, Apratim Maity, Subhasis Batabyal, Dipak Banerjee","doi":"10.1080/09291016.2023.2266544","DOIUrl":"https://doi.org/10.1080/09291016.2023.2266544","url":null,"abstract":"ABSTRACTThe adaptive physiological functions of black Bengal goats (Capra hircus) of coastal regions were compared with goats from the plains during winter, spring, and summer seasons. Goats in the coastal zone had significantly (P < 0.01) higher plasma electrolytes levels. Goats in the plains zone had significantly (P < 0.01) higher haemoglobin, PCV, TEC, and erythrocyte indices and lower TLC values. Glucose, total protein, and creatinine were significantly (P < 0.01) lower, whereas cholesterol, BUN, and SGPT were significantly (P < 0.01) higher in goats of coastal zone. Regardless of zones, glucose, total protein, and creatinine levels were higher in winter, cholesterol and SGOT levels were higher in spring, and BUN was higher in summer. Goats from coastal areas had significantly (P < 0.05) higher urinary pH and urea levels. Goats in the coastal zone had significantly (P < 0.05) higher cortisol concentrations. From the above study, we can conclude that salinity of feed, soil and water does not significantly affect the homeostasis of black Bengal goats reared in coastal areas, indicating their adaptability to saline coastal environments and their potential for reproduction in a climate-resilient livestock system.HIGHLIGHTS The fodder, water and soil of coastal areas contain higher amounts of sodium, zinc, and iron in the compared to plain areas.Black Bengal goats raised in coastal regions are able to maintain their homeostasis without much altering hemato-biochemical and endocrine profiles.Black Bengal goats can be a good option for climate resilient animal husbandry system.KEYWORDS: Salinityblack Bengal goatsadaptationphysio-biochemicalendocrine AcknowledgmentsThe authors are thankful to the Vice-Chancellor, WBUAFS along with the All India Coordinated Research Project (AICRP, ICAR) on goats and ICAR-IVRI, ERS for providing necessary supports for this study.","PeriodicalId":9208,"journal":{"name":"Biological Rhythm Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135825339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACT The current study aims to describe the functional changes in Murrah buffalo PBMCs during chronic in-vitro thermal stress. Thus, PBMCs were stimulated at 34°C or 37°C or 40°C for 0 hr, 24 hrs and 48 hrs. At the end of each treatment, mRNA abundance of genes related to heat shock (HSP10, HSP40, HSP60, HSP70, HSP90 and HSF1), inflammation (IL1β, IL6, IL 12 and INF γ), cell viability (Bax and Bcl2) and natural resistance-associated macrophage protein (SLC11A1) were quantified by qPCR. The results revealed upregulation (p < 0.05) in mRNA expression of HSP10, HSP40, HSP60, HSP70, HSF1, IL1β, IL6, IL12, INF γ, BAX, BCL2 and SLC11A1 gene in chronically (24 and 48 hrs) thermal stressed (40 °C) PBMCs than cells maintained at 34 °C or 37 °C. In conclusion, chronic thermal stress directly affects the functionality of Murrah buffalo PBMCs and is likely responsible for immune alterations during thermal stress.KEYWORDS: Heat stressimmune cellsgene expressioninflammationcell viability Disclosure statementNo potential conflict of interest was reported by the author(s).Additional informationFundingThe work was supported by the Tamilnadu Veterinary and Animal Sciences University.
{"title":"Chronic <i>in vitro</i> thermal stress alters functional response of peripheral blood mononuclear cells of Murrah buffalo","authors":"Thangaraju Kavin, Venkatasubramanian Leela, Gopalakrishnan Suganya, Senthilkumar TMA, Kandasamy Rajamanickam","doi":"10.1080/09291016.2023.2267949","DOIUrl":"https://doi.org/10.1080/09291016.2023.2267949","url":null,"abstract":"ABSTRACT The current study aims to describe the functional changes in Murrah buffalo PBMCs during chronic in-vitro thermal stress. Thus, PBMCs were stimulated at 34°C or 37°C or 40°C for 0 hr, 24 hrs and 48 hrs. At the end of each treatment, mRNA abundance of genes related to heat shock (HSP10, HSP40, HSP60, HSP70, HSP90 and HSF1), inflammation (IL1β, IL6, IL 12 and INF γ), cell viability (Bax and Bcl2) and natural resistance-associated macrophage protein (SLC11A1) were quantified by qPCR. The results revealed upregulation (p < 0.05) in mRNA expression of HSP10, HSP40, HSP60, HSP70, HSF1, IL1β, IL6, IL12, INF γ, BAX, BCL2 and SLC11A1 gene in chronically (24 and 48 hrs) thermal stressed (40 °C) PBMCs than cells maintained at 34 °C or 37 °C. In conclusion, chronic thermal stress directly affects the functionality of Murrah buffalo PBMCs and is likely responsible for immune alterations during thermal stress.KEYWORDS: Heat stressimmune cellsgene expressioninflammationcell viability Disclosure statementNo potential conflict of interest was reported by the author(s).Additional informationFundingThe work was supported by the Tamilnadu Veterinary and Animal Sciences University.","PeriodicalId":9208,"journal":{"name":"Biological Rhythm Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135994360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-17DOI: 10.1080/09291016.2023.2267953
Abdelrahman A. Kilany, Abdel-Halim A. El-Darawany, Akram A. EL-Tarabany, Khaled M. Al-Marakby
ABSTRACTThe aim was to investigate effects of ambient temperature-humidity index (THI) on the reproductive indices of 920 Holstein (HO) cows in the subtropics. THI was categorized as low: below 70; moderate: from 70 to 75 and high: more than 75. The high THI significantly (P < 0.001) prolonged the periods of calving interval, days open and dry period, and increased the service per conception rate. The conception rate in the high THI group (17.31%) was significantly (P < 0.001) lower than that noticed in both low (36.96%) and moderate THI (31.61%) groups. Meanwhile, high THI significantly increased the embryonic loss (P < 0.001) and abortion (P=0.043) rates compared with low (14.62% and 8.89%; respectively) and moderate (22.84%; and 11.17%; respectively) THI groups. The high THI group had a significantly (P=0.001) greater embryonic losses than the other groups. Conclusively, THI over 75 deteriorates the reproductive indices of Holstein cows.KEYWORDS: Holsteinheat stressTHIreproductive indices AcknowledgmentsThe authors are grateful to Dr Mohammed Abdel-Hameed, the dairy farm (station 2) manager, El Salhiya Company for investment and development, New Salhiya, Sharkia governorate, Egypt, and his team for their cooperation in this study.Authors contributionsAbdelrahman Kilany: data collection, analysis and MS drafting. Abdel-Halim El-Darawany: data collection, analysis and MS drafting. Akram El-Tarabany: data collection, analysis and MS drafting. Khaled Al-Marakby: data collection, analysis and MS drafting.Disclosure statementNo potential conflict of interest was reported by the author(s).Data availability statementAll data generated or analyzed during this study are included in this published paperEthical approvalThis work was reviewed and approved by the Animal Care and Welfare Committee of Egyptian Atomic Energy Authority standard operating procedures.
{"title":"Effect of environmental thermal stress on reproductive performance of Holstein cows in Egypt","authors":"Abdelrahman A. Kilany, Abdel-Halim A. El-Darawany, Akram A. EL-Tarabany, Khaled M. Al-Marakby","doi":"10.1080/09291016.2023.2267953","DOIUrl":"https://doi.org/10.1080/09291016.2023.2267953","url":null,"abstract":"ABSTRACTThe aim was to investigate effects of ambient temperature-humidity index (THI) on the reproductive indices of 920 Holstein (HO) cows in the subtropics. THI was categorized as low: below 70; moderate: from 70 to 75 and high: more than 75. The high THI significantly (P < 0.001) prolonged the periods of calving interval, days open and dry period, and increased the service per conception rate. The conception rate in the high THI group (17.31%) was significantly (P < 0.001) lower than that noticed in both low (36.96%) and moderate THI (31.61%) groups. Meanwhile, high THI significantly increased the embryonic loss (P < 0.001) and abortion (P=0.043) rates compared with low (14.62% and 8.89%; respectively) and moderate (22.84%; and 11.17%; respectively) THI groups. The high THI group had a significantly (P=0.001) greater embryonic losses than the other groups. Conclusively, THI over 75 deteriorates the reproductive indices of Holstein cows.KEYWORDS: Holsteinheat stressTHIreproductive indices AcknowledgmentsThe authors are grateful to Dr Mohammed Abdel-Hameed, the dairy farm (station 2) manager, El Salhiya Company for investment and development, New Salhiya, Sharkia governorate, Egypt, and his team for their cooperation in this study.Authors contributionsAbdelrahman Kilany: data collection, analysis and MS drafting. Abdel-Halim El-Darawany: data collection, analysis and MS drafting. Akram El-Tarabany: data collection, analysis and MS drafting. Khaled Al-Marakby: data collection, analysis and MS drafting.Disclosure statementNo potential conflict of interest was reported by the author(s).Data availability statementAll data generated or analyzed during this study are included in this published paperEthical approvalThis work was reviewed and approved by the Animal Care and Welfare Committee of Egyptian Atomic Energy Authority standard operating procedures.","PeriodicalId":9208,"journal":{"name":"Biological Rhythm Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135993948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACTChronotypes describe morningness/eveningness preference Society is morning-oriented and late chronotypes suffer and function in hours that are different from their innate preference (social jetlag). Data suggest links between chronotypes and psychological wellbeing, but relationships are unclear. We explore this relationship using a combined measure representing different domains of psychological wellbeing. Participants (177 adults) were reached through social media and asked to answer questionnaires including demographic and health information; morningness/eveningness (MEQ); State-Trait Anxiety Inventory Y-1 (STAI-Y1); Center for Epidemiologic Studies Depression Scale (CES-D); Risk Assessment Suicidality Scale (RASS); and Quality of Life Uniscale (QoL). Data were transformed using Z-Scores and summed to generate a “Psychological wellbeing” variable. Three variables survived the regression model as contributors to wellbeing: chronotype, general health and past mental health issues. Chronotypes therefore have a significant effect on psychological wellbeing and as a society we may want to take action to assist late chronotypes overcome their challenge.KEYWORDS: Circadian rhythmsquality of lifeemotionalitydepressionanxiety Disclosure statementNo potential conflict of interest was reported by the author(s).
{"title":"Late chronotypes show lower scores on a combined measure of emotional wellbeing: a study in the general population in Greece","authors":"Haim Einat, Vasia Kirgiakou, Aikaterini Stravoravdi, Yelena Stukalin, Anat Lan, Konstantinos Fountoulakis","doi":"10.1080/09291016.2023.2262096","DOIUrl":"https://doi.org/10.1080/09291016.2023.2262096","url":null,"abstract":"ABSTRACTChronotypes describe morningness/eveningness preference Society is morning-oriented and late chronotypes suffer and function in hours that are different from their innate preference (social jetlag). Data suggest links between chronotypes and psychological wellbeing, but relationships are unclear. We explore this relationship using a combined measure representing different domains of psychological wellbeing. Participants (177 adults) were reached through social media and asked to answer questionnaires including demographic and health information; morningness/eveningness (MEQ); State-Trait Anxiety Inventory Y-1 (STAI-Y1); Center for Epidemiologic Studies Depression Scale (CES-D); Risk Assessment Suicidality Scale (RASS); and Quality of Life Uniscale (QoL). Data were transformed using Z-Scores and summed to generate a “Psychological wellbeing” variable. Three variables survived the regression model as contributors to wellbeing: chronotype, general health and past mental health issues. Chronotypes therefore have a significant effect on psychological wellbeing and as a society we may want to take action to assist late chronotypes overcome their challenge.KEYWORDS: Circadian rhythmsquality of lifeemotionalitydepressionanxiety Disclosure statementNo potential conflict of interest was reported by the author(s).","PeriodicalId":9208,"journal":{"name":"Biological Rhythm Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135924306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-13DOI: 10.1080/09291016.2023.2256522
H. Suárez, A. Guerra, R. Mansilla, J.M. Nieto-Villar
The process of ferroptosis has become an alternative therapy to fight cancer. As a continuation of previous work, a non-autonomous model was developed for avascular and vascular tumor growth under periodic perturbations that simulate the application of a chronotherapeutically modulated treatment based on triggering the ferroptosis process. It was found that for critical amplitude and a perturbation frequency of twice the autonomous frequency in vascular growth, less complex and therefore less robust states are reached, and the tumor population decreases.
{"title":"Ferroptosis as a biological Phase transition II: Chronotherapy of avascular and vascular tumor growth","authors":"H. Suárez, A. Guerra, R. Mansilla, J.M. Nieto-Villar","doi":"10.1080/09291016.2023.2256522","DOIUrl":"https://doi.org/10.1080/09291016.2023.2256522","url":null,"abstract":"The process of ferroptosis has become an alternative therapy to fight cancer. As a continuation of previous work, a non-autonomous model was developed for avascular and vascular tumor growth under periodic perturbations that simulate the application of a chronotherapeutically modulated treatment based on triggering the ferroptosis process. It was found that for critical amplitude and a perturbation frequency of twice the autonomous frequency in vascular growth, less complex and therefore less robust states are reached, and the tumor population decreases.","PeriodicalId":9208,"journal":{"name":"Biological Rhythm Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135690662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-04DOI: 10.1080/09291016.2023.2254205
Rola al Balushi, Richard Carciofo
ABSTRACT Evening chronotype is associated with more frequent binge-eating, depression, and less frequent breakfast consumption. The current study investigated whether skipping breakfast mediates the relationships between chronotype and binge-eating, and chronotype and depression. 272 participants completed an online survey with questionnaire measures of chronotype/morningness-eveningness, binge-eating, depression, and meal skipping. Significant positive correlations were found between eveningness and skipping breakfast, eveningness and depression, skipping breakfast and depression, and skipping breakfast and binge-eating. Eveningness was also correlated with binge-eating, and although this was not statistically significant, mediation analysis revealed a significant indirect effect of eveningness on binge-eating through skipping breakfast. The indirect effect of eveningness on depression through skipping breakfast was not significant, but the indirect effect sequentially through breakfast skipping and binge-eating was significant. The current findings indicate potential mechanisms for the inter-relationships between eveningness, breakfast skipping, binge-eating, and depression, which may be more fully investigated in research utilising longitudinal designs.
{"title":"Chronotype, binge-eating, and depression: the mediating effect of skipping breakfast","authors":"Rola al Balushi, Richard Carciofo","doi":"10.1080/09291016.2023.2254205","DOIUrl":"https://doi.org/10.1080/09291016.2023.2254205","url":null,"abstract":"ABSTRACT Evening chronotype is associated with more frequent binge-eating, depression, and less frequent breakfast consumption. The current study investigated whether skipping breakfast mediates the relationships between chronotype and binge-eating, and chronotype and depression. 272 participants completed an online survey with questionnaire measures of chronotype/morningness-eveningness, binge-eating, depression, and meal skipping. Significant positive correlations were found between eveningness and skipping breakfast, eveningness and depression, skipping breakfast and depression, and skipping breakfast and binge-eating. Eveningness was also correlated with binge-eating, and although this was not statistically significant, mediation analysis revealed a significant indirect effect of eveningness on binge-eating through skipping breakfast. The indirect effect of eveningness on depression through skipping breakfast was not significant, but the indirect effect sequentially through breakfast skipping and binge-eating was significant. The current findings indicate potential mechanisms for the inter-relationships between eveningness, breakfast skipping, binge-eating, and depression, which may be more fully investigated in research utilising longitudinal designs.","PeriodicalId":9208,"journal":{"name":"Biological Rhythm Research","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47334347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-30DOI: 10.1080/09291016.2023.2252221
Xingping Wang, Zhe Wang, Chuan-Li Wang, Huiliang Xue, Ming Wu, Lei Chen, Chao Fan, Jin-hui Xu, Laixiang Xu
ABSTRACT Changes in photoperiod affect both oxidative stress (OS) levels and antioxidant enzyme activities in animals. The liver accounts for a vital body metabolic organ. Different light durations may produce different outcomes in terms of OS and liver antioxidant pathways, but the underlying mechanism is not yet understood. This study investigated the effects of diverse photoperiods (SD, short day; MD, moderate day; LD, long day) on OS degree (H2O2 and MDA), antioxidant enzyme activities (superoxide dismutase [SOD], catalase [CAT], and glutathione peroxidase [GPx]), liver total antioxidant capacity, and the Nrf2-Keap1 signaling pathway in striped dwarf hamsters (Cricetulus barabensis) livers. Our results showed that (1) SD treatment for 8 weeks increased the levels of phosphorylated Nrf2, upregulated the Nrf2-Keap1 signaling pathway, and increased the protein expression of SOD and GPx, while decreasing the MDA concentration, all of which reduced the OS degree. (2) Additionally, LD treatment for 8 weeks reduced the extent of Nrf2 phosphorylation, resulting in downregulation of the Nrf2-Keap1 pathway, thus reducing protein expression of SOD2 and CAT, increasing the concentrations of H2O2 and MDA, and increasing OS degree. Collectively, OS levels in C. barabensis liver decreased during SD but increased during LD.
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