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PRP Versus Standard of Care for Venous leg Ulcers: A Systematic Review and Meta-Analysis of Prospective Comparative Studies. PRP 与静脉性腿部溃疡的标准疗法:前瞻性比较研究的系统回顾与元分析》。
Pub Date : 2022-04-14 DOI: 10.1177/15347346221094424
Kaissar Yammine, Joe Ghanimeh, Sira Jil Agopian, Chahine Assi, Fady Hayek

Venous leg ulcers (VLUs) are chronic and recalcitrant lower limb wounds that affect millions of patients annually, severely reducing their quality of life, and causing a significant burden on the health care system. Recently, Platelet rich plasma (PRP) has been used to improve healing of VLUs. This systematic review aimed at evaluating the effectiveness of PRP versus the standard of care commonly used to treat VLUs. Ten prospective studies (8 randomized) met the inclusion criteria comprising 451 patients with 527 VLUs. Results were as follows: a) the weighted Odds Ratio (OR) of the mean healing rate was 2.84 (95% CI = 1.160 to 5.056, I2 = 41.4%, p = 0.0004), b) the mean healed ulcer areas were 79.2 ± 19% for the PRP group and 51.7 ± 36% for the control group (p = 0.007) in favor of the PRP group, and c) the weighted infection OR showed no significant difference between both groups. Additionally, negative correlations were found between healing rate and duration of VLUs and initial size of the ulcers. This meta-analysis demonstrated significant beneficial effects of PRP versus standard of care on healing rate, reduction in surface, and reduction in healing time of VLUs. Infection and other complications were similar to standard of care. Therefore, our analytical data would support the use of PRP as a safe and effective treatment for VLUs.

腿部静脉溃疡(VLUs)是一种慢性顽固性下肢伤口,每年影响数百万患者,严重降低了他们的生活质量,并给医疗保健系统造成沉重负担。最近,富血小板血浆(PRP)被用于改善 VLU 的愈合。本系统综述旨在评估富血小板血浆与治疗 VLU 的常用标准护理方法的有效性。有 10 项前瞻性研究(8 项随机研究)符合纳入标准,包括 451 位 527 例 VLU 患者。结果如下:a)平均愈合率的加权比值比(OR)为 2.84(95% CI = 1.160 至 5.056,I2 = 41.4%,p = 0.0004);b)PRP 组的平均愈合溃疡面积为 79.2 ± 19%,对照组为 51.7 ± 36%(p = 0.007),PRP 组更胜一筹;c)加权感染比值比显示两组之间无显著差异。此外,VLU 的愈合率和持续时间与溃疡的初始大小呈负相关。这项荟萃分析表明,PRP 与标准护理相比,对 VLU 的愈合率、溃疡面缩小和愈合时间缩短都有显著的益处。感染和其他并发症与标准护理相似。因此,我们的分析数据支持使用 PRP 安全有效地治疗 VLU。
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引用次数: 0
A 英语字母表的第1个字母
Pub Date : 2021-11-08 DOI: 10.1515/9783111697888-026
J. Haynes
The information society has generated new digital literacy which, because of its aspects and implications for education, training and the workplace, has coined the term digital competence. This articled deals with the problem of digital competence of citizens, understood as a key element for performing in the knowledge society, and putting the potential and opportunities offered by digital technology to its best use in different areas of professional and personal development of individuals. To this end, it addresses the issue of digital competence, the digital divide as an element that hinders development and proposes a set of recommendations that would facilitate the development of digital competence of citizens.
信息社会产生了新的数字素养,由于其对教育、培训和工作场所的影响,创造了“数字能力”一词。本文讨论了公民的数字能力问题,将其理解为在知识社会中表现的关键因素,并将数字技术提供的潜力和机会最佳地用于个人职业和个人发展的不同领域。为此,它解决了数字能力问题,即数字鸿沟是阻碍发展的一个因素,并提出了一套有助于发展公民数字能力的建议。
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引用次数: 0
W W
Pub Date : 2021-08-31 DOI: 10.1515/9783111350486-021
B. A. Orcutt
FEVER, Dr Davis's scientific and popular view of, E. M. S. J. vi. 558. observations concerning it, E. M. S. J. vi. l262. Sir Gilbert Blane's observations on, E. M. S. J. ix. 194. Sir J. Fellowes's observations on, E. M. S. J. xii. 114. WALKER, (Dr JAMES), some Recount of the effect of antimoriial wine, E. P. L. ii. 2.54. WALKER, (Dr HENRY), on the varieties of ophthalmia, E. M. S. J. vii. 1. WALKER, (JOHN), case of petechia; sine febre cured by sulphuric acid, A. M. ii. 231. WALKER, (Mr JOHN), reply to Moore on vaccination, E. M. S. J. xxv. 383 WALKER, (Dr JOSHUA), on the use of cuprum ammoniacum, M. C. x. 2S8.
然而,戴维斯博士的科学和大众观点,E.M.s.J.vi.558。关于它的意见,E.M.S.J.vi.l262。Gilbert Blane爵士对的意见,E.M.s.J.ix.194。费罗斯爵士的意见,E.M.s.J.xii。114.沃克,(詹姆斯博士),《关于葡萄酒抗霉菌作用的一些回忆》,E.P.L.ii。2.54.沃克,(亨利博士),关于眼炎的变种,E.M.S.J.vii。1.沃克,(约翰),瘀点病例;用硫酸固化的辛非布雷,A.M.ii。231.沃克,(约翰先生),就疫苗接种问题答复Moore,E.M.S.J.xxv。383沃克,(乔舒亚博士),关于氨铜的使用,M.C.x.2S8。
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引用次数: 0
S 英语字母表的第19个字母
Pub Date : 2021-08-31 DOI: 10.1515/9783110968545-092
R. Carlton
All habitat suitability, use, movement, and landscape genetic analyses were conducted in R [1] across the whole of San Diego County. We created these initial models using relevant environmental variables for habitat use and movement for all focal species (Table S1) using an ecological neighborhood approach. To select the most appropriate scale for each variable, we used the smoothie package (v 1.0-1, [2]) to apply a Gaussian smooth to each variable at a variety of biologically-relevant spatial scales for each species based on movement and home range information for each species. We tested scales ranging from 30 m to 180 m for California mouse and woodrat, 30 m to 360 m for wrentit, 30 m to 2,160 m for mule deer, 30 m to 2,000 m for bobcat, and 30 m to 10,000 m for puma.
所有栖息地的适宜性、使用、移动和景观遗传分析都在整个圣地亚哥县的R[1]中进行。我们使用生态邻域方法,使用所有重点物种的栖息地使用和移动的相关环境变量创建了这些初始模型(表S1)。为了为每个变量选择最合适的尺度,我们使用奶昔包(v 1.0-1,[2]),基于每个物种的运动和家庭范围信息,在每个物种的各种生物相关空间尺度上对每个变量应用高斯平滑。我们测试了加州老鼠和林鼠30米至180米的鳞片,花圈猴30米至360米,骡子鹿30米至2160米,山猫30米至2000米,美洲狮30米至10000米。
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引用次数: 0
D D
Pub Date : 2021-06-01 DOI: 10.1515/9783111548050-015
M. Anni, Il Direttore
This chapter of the historic context is organized in three sections that define the various suburban property types found in the study area. Each section provides a brief history of the suburban building type, criteria by which to assess its significance, and a list of character-defining elements (CDEs) to aid in its evaluation. The CDEs were developed from general research on the property types. They will be checked for consistency in the field and may need to be revised following intensive on-site survey as the project progresses. The evaluation criteria and CDEs are applicable to individual structures, as well as to entire neighborhoods.
这一章的历史文脉分为三个部分,定义了研究区域内的各种郊区房产类型。每个部分都提供了郊区建筑类型的简史,评估其重要性的标准,以及帮助其评估的特征定义元素(CDEs)列表。cde是从对属性类型的一般研究发展而来的。将在实地检查它们的一致性,并可能需要随着项目进展在密集的现场调查后进行修订。评估标准和cde既适用于个别结构,也适用于整个社区。
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引用次数: 0
L l
Pub Date : 2021-06-01 DOI: 10.1515/9783111697888-037
ogod Jo dltsre, Uun, oluetur€s ounJg Jord, flnolf ulisasau
course ana termination, iVl.
课程结束,iVl
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引用次数: 0
R R
Pub Date : 2021-06-01 DOI: 10.1515/9783111697888-020
Mittelburgi grassantium
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引用次数: 0
W 英语字母表的第23个字母
Pub Date : 2020-12-31 DOI: 10.1515/9783111697888-024
W. R. Bion
Estamos gratos a Francesca Bion por nos permitir pu blicar a presente transcrição. Esta, belamente transmite os amplos po deres do pensamento reflexivo e especulativo de Bion, assim como, sua p eculiaridade de formular perguntas em vez de respondê-las. O que, a meu ver, não é possível veicular, satisfatoriamente, na modalidade escrita, é o andam ento das comunicações de Bion no seminário. Pelos padrões da linguagem co loquial e acadêmica de praxe, ele aqui fala de maneira bem lenta mas de um a forma que engendra incrível sensação de abertura, de curiosidade e vit alidade. Os que leram as obras de Bion por certo vão notar que ele diz neste seminário várias coisas que já dissera antes. É, no entanto, surpreendente que até essas idéias, com que estaríamos familiarizados (talvez ultrafamiliar izados), nos chegam neste seminário a partir de uma direção inesperada.
我们感谢Francesca Bion允许我们发表这份成绩单。这很好地传达了比昂广泛的反思和思辨能力,以及他提出问题而不是回答问题的能力。在我看来,无法以书面形式令人满意地传达的是比昂在研讨会上的沟通进展。按照通常口语和学术语言的标准,他在这里说话很慢,但在某种程度上产生了一种令人难以置信的开放感、好奇心和活力。读过比昂著作的人一定会注意到,他在这次研讨会上说了几句他以前说过的话。然而,令人惊讶的是,即使是这些我们熟悉(也许非常熟悉)的想法,在这次研讨会上也从一个意想不到的方向来到了我们面前。
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引用次数: 0
Z 英语字母表的第26个字母
Pub Date : 2020-12-31 DOI: 10.1515/9783111697888-048
Zhifeng Ren
EIGENSCHAFTEN • Die Siebdruckfarbserie Z ist Lösemittel basiert und wird zweikomponentig mit Härter verarbeitet. • Z ist gut verdruckbar, trocknet chemisch-physikalisch und zeigt ein glänzendes Oberflächenfinish. • Die Farbe wird besonders im technisch/industriellen Bereich eingesetzt, wenn hohe Beständigkeitsanforderungen zu erfüllen sind. • Ausgehärtete Drucke verfügen über hohe mechanische Festigkeit sowie gute chemische Beständigkeit gegenüber vielen organischen Lösemitteln, verdünnten Alkalien und Säuren, Ölen und Fetten. • Durch Einstellung mit schnellflüchtigen Verdünnern, z.B. ZVSP, lässt sich die Siebdruckfarbe Z auch mit einer Lackierspritzpistole applizieren. • Die Farbserie Z ist bindemittelbedingt (Epoxidharz) nicht witterungsbeständig. Sie ist für den Innenund kurzfristigen Außeneinsatz geeignet. Mögliche witterungsbeständige Alternativen wären die Farbserien ZM und ZMN. • Hinweis: Vorversuche zur Eignung dieser Farbe werden auf Grund der Vielfältigkeit der Substrate/ Bedruckstoffe dringend empfohlen. Auch die Effizienz einer ggf. erforderlichen Substratvorbehandlung durch Vorreinigung/Entfettung, Vorbehandlung durch Flamme, Corona, Plasma oder z.B. einer Nachbehandlung (Flammtrocknung) ist zu prüfen.
品质•Siebdruckfarbserie Z Lösemittel为基础,将zweikomponentig努力处理.•Z verdruckbar很好,干chemisch-physikalisch和显示一辆锃亮Oberflächenfinish .•颜色特别会在技术/工业领域使用大额Beständigkeitsanforderungen途径可循.•Ausgehärtete出版拥有高的机械强度,以及良好的化学稳定性对许多有机Lösemitteln, verdünnten Alkalien酸、精油和胖.•通过态度同schnellflüchtigen Verdünnern,比如. ZVSP也烦恼,Z Siebdruckfarbe Lackierspritzpistole applizieren .•Farbserie Z bindemittelbedingt (Epoxidharz)是不witterungsbeständig .它可用作内部及短期内的外力选择给档案室和ZMN。•注意:Vorversuche旨在为这些颜色会基于多种可能性Substrate / Bedruckstoffe强烈推荐.前提是家长参与应研究下等人的先天处理;火、Corona、血浆或管道等次处理。
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引用次数: 0
O O
Pub Date : 2020-08-14 DOI: 10.1515/9783111548050-026
Nichtamtliche Lesefassung
: This paper analyzes Adélia, Joana, and Quiquina, black characters in the Lucas Procópio (1985) and Ópera dos mortos (1967) novels, by Autran Dourado. Although they are all black, there is a disparity between them. While the first is a mulatto who exchanges her freedom for sexual favors, freed by colonel Lucas Procópio – Isaltina’s husband – the others are portrayed as enslaved women living for sinhá Isaltina and boss Rosalina. For the social space occupied by these characters and the historical moment portrayed in the work analysis, this article is based on Gilberto Freyre (1933) and Roberto Reis (1987),
本文分析了Autran Dourado的小说Lucas Procópio(1985)和Ópera dos mortos(1967)中的黑人角色ad、Joana和Quiquina。虽然他们都是黑人,但他们之间存在差异。第一个是混血儿,她用自己的自由换取性服务,被卢卡斯上校Procópio——Isaltina的丈夫释放了,而其他人则被描绘成为sinhisaltina和老板Rosalina生活的奴隶妇女。对于这些人物所占据的社会空间和作品分析中所描绘的历史时刻,本文以Gilberto Freyre(1933)和Roberto Reis(1987)为基础,
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引用次数: 0
期刊
Edinburgh medical and surgical journal
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