Pub Date : 2026-01-16DOI: 10.1016/j.bja.2025.12.033
Wilton A van Klei,Justyna Bartoszko,Joshua Andrusiak,Michael Santema,Marije Marsman
{"title":"Risk of periprocedural regurgitation of gastric contents in patients on glucagon-like peptide-1 receptor agonists: a two-centre nested case-control study.","authors":"Wilton A van Klei,Justyna Bartoszko,Joshua Andrusiak,Michael Santema,Marije Marsman","doi":"10.1016/j.bja.2025.12.033","DOIUrl":"https://doi.org/10.1016/j.bja.2025.12.033","url":null,"abstract":"","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":"4646 3 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145993078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-16DOI: 10.1016/j.bja.2025.12.029
Daniel I Sessler
Well-written scientific and medical manuscripts convey precise meaning and are therefore likely to sway opinions and effect change. Clear publications disseminate ideas and perspectives, making them likely to be published, read, and cited. Here, I share some suggestions that make writing forceful, easy to understand, and more effective.
{"title":"Let me be clear….","authors":"Daniel I Sessler","doi":"10.1016/j.bja.2025.12.029","DOIUrl":"https://doi.org/10.1016/j.bja.2025.12.029","url":null,"abstract":"<p><p>Well-written scientific and medical manuscripts convey precise meaning and are therefore likely to sway opinions and effect change. Clear publications disseminate ideas and perspectives, making them likely to be published, read, and cited. Here, I share some suggestions that make writing forceful, easy to understand, and more effective.</p>","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145994170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-16DOI: 10.1016/j.bja.2025.12.020
Clístenes Crístian de Carvalho
High-flow nasal oxygen (HFNO) is increasingly used for preoxygenation, yet the optimal flow rate remains uncertain. Sjöblom and colleagues compared 45, 70, and 95 L min-1 and found no significant differences in safe apnoea time when HFNO was stopped at apnoea onset and the airway left open to atmosphere. This commentary reflects on why, under their study design, higher flows might not be expected to extend safe apnoea time and shows that clinically relevant differences (≈2-3 min) cannot be excluded from the summary data. It places the findings within their physiological context and discusses why results may differ if HFNO is continued through apnoea, if patient positioning varies, or when patient-level factors are taken into account. It also emphasises that the absence of a statistically significant difference does not constitute evidence of equivalence and proposes a pragmatic approach to preoxygenation.
高流量鼻氧（HFNO）越来越多地用于预充氧，但最佳流量仍不确定。Sjöblom和同事比较了45、70和95 L min-1，发现在呼吸暂停开始时停止HFNO和气道对大气开放时，安全呼吸暂停时间没有显著差异。这篇评论反映了为什么在他们的研究设计下，高流量可能不会延长安全呼吸暂停时间，并表明临床相关差异（≈2-3分钟）不能从总结数据中排除。它将研究结果置于其生理背景下，并讨论了如果在呼吸暂停期间继续进行高强度no，如果患者体位不同，或者考虑到患者层面的因素，结果可能会有所不同的原因。它还强调，没有统计上显著的差异并不构成等效的证据，并提出了一种实用的预充氧方法。
{"title":"Preoxygenation with high-flow nasal oxygen: the role of flow rate in safe apnoea time.","authors":"Clístenes Crístian de Carvalho","doi":"10.1016/j.bja.2025.12.020","DOIUrl":"https://doi.org/10.1016/j.bja.2025.12.020","url":null,"abstract":"High-flow nasal oxygen (HFNO) is increasingly used for preoxygenation, yet the optimal flow rate remains uncertain. Sjöblom and colleagues compared 45, 70, and 95 L min-1 and found no significant differences in safe apnoea time when HFNO was stopped at apnoea onset and the airway left open to atmosphere. This commentary reflects on why, under their study design, higher flows might not be expected to extend safe apnoea time and shows that clinically relevant differences (≈2-3 min) cannot be excluded from the summary data. It places the findings within their physiological context and discusses why results may differ if HFNO is continued through apnoea, if patient positioning varies, or when patient-level factors are taken into account. It also emphasises that the absence of a statistically significant difference does not constitute evidence of equivalence and proposes a pragmatic approach to preoxygenation.","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":"270 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145993039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bupivacaine pharmacokinetics in the absence or presence of perineural dexamethasone in axillary blockade.","authors":"Daniela Bravo,Germán Aguilera,Ady Giordano,Sebastián Layera,Hans Erpel,Diego Mora,Carla Ramírez,Álvaro Jara,Julián Aliste","doi":"10.1016/j.bja.2025.12.009","DOIUrl":"https://doi.org/10.1016/j.bja.2025.12.009","url":null,"abstract":"NCT05359731.","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":"36 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145993080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-16DOI: 10.1016/j.bja.2025.12.024
Katherine McKee,James Turnbull,Anil Patel,Archie I J Brain
{"title":"Laryngeal mask airway sizes: evaluation of the use of the size 6 LMA.","authors":"Katherine McKee,James Turnbull,Anil Patel,Archie I J Brain","doi":"10.1016/j.bja.2025.12.024","DOIUrl":"https://doi.org/10.1016/j.bja.2025.12.024","url":null,"abstract":"","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":"269 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145993082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-13DOI: 10.1016/j.bja.2025.12.011
Ge Li
{"title":"Intraoperative electroencephalogram-derived measures and their association with postoperative delirium: anaesthetic and surgical heterogeneity in EEG–delirium research. Comment on Br J Anaesth 2025; 135: 1684–1703","authors":"Ge Li","doi":"10.1016/j.bja.2025.12.011","DOIUrl":"https://doi.org/10.1016/j.bja.2025.12.011","url":null,"abstract":"","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":"32 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145961649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-13DOI: 10.1016/j.bja.2025.12.014
David Ferreira, Francis Berthier
{"title":"Association of intraoperative end-tidal CO2 levels with postoperative outcomes. Comment on Br J Anaesth 2025; 135: 1761–9","authors":"David Ferreira, Francis Berthier","doi":"10.1016/j.bja.2025.12.014","DOIUrl":"https://doi.org/10.1016/j.bja.2025.12.014","url":null,"abstract":"","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":"142 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145962451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-09DOI: 10.1016/j.bja.2025.11.055
Peter J Schuller,Jan P G Pretorius
{"title":"qNOX index for quantification of intraoperative nociception and analgesia: the problem of neuromuscular block. Comment on Br J Anaesth 2025; 134: 736-45.","authors":"Peter J Schuller,Jan P G Pretorius","doi":"10.1016/j.bja.2025.11.055","DOIUrl":"https://doi.org/10.1016/j.bja.2025.11.055","url":null,"abstract":"","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":"9 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145947426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-09DOI: 10.1016/j.bja.2025.12.006
Harriet E Taylor,Joseph C Salf,Charlotte R Roper-Marchand,Dhaneesha N S Senaratne,Blair H Smith,Lesley A Colvin,Jacob George
{"title":"Are adults with chronic pain more likely to develop hypertension than adults without chronic pain? Response to Br J Anaesth 2026; 136: 429-31.","authors":"Harriet E Taylor,Joseph C Salf,Charlotte R Roper-Marchand,Dhaneesha N S Senaratne,Blair H Smith,Lesley A Colvin,Jacob George","doi":"10.1016/j.bja.2025.12.006","DOIUrl":"https://doi.org/10.1016/j.bja.2025.12.006","url":null,"abstract":"","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":"29 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145947461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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