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Transient Brugada-Like Electrocardiogram Configuration Provoked by COVID-19 Fever COVID-19发热引起的瞬态brugada样心电图配置
Pub Date : 2023-01-31 DOI: 10.51200/bjms.v17i1.3563
May Honey Ohn, Jun Rong Ng, Khin Maung Ohn, Pan Nyein Han
There are varieties of cardiac complications which can occur in COVID-19 encompassing acute coronary syndrome, myocarditis to arrhythmia. We report a case of COVID-19 infected patient who presented with a high fever which provokes transient Type 1 Brugada-like ECG configuration. Brugada syndrome is a potentially life-threatening arrhythmia which could lead to sudden cardiac death secondary to ventricular arrhythmias. Being commonly asymptomatic, there are many triggers which could lead to its manifestations and subsequent complications. While fever, being one of the triggers, is the most common presentation of COVID-19. Besides, it could be multifactorial, either from the variant systemic complications in COVID-19 or from the management itself, especially common drugs used in resuscitation which could provoke the Brugada pattern. Looking at this association, ECG monitoring then becomes important in COVID-19, especially in those with chest pain and fever. Proper treatment for fever in COVID-19 is prudent to avoid malignant arrhythmia.
COVID-19可发生多种心脏并发症,包括急性冠状动脉综合征、心肌炎和心律失常。我们报告一例COVID-19感染患者,其表现为高热,引起短暂的1型brugada样心电图配置。Brugada综合征是一种潜在危及生命的心律失常,可导致继发于室性心律失常的心源性猝死。由于通常无症状,有许多诱因可导致其表现和随后的并发症。而发烧是触发因素之一,是COVID-19最常见的表现。此外,它可能是多因素的,既可能来自COVID-19的各种系统性并发症,也可能来自管理本身,特别是复苏中使用的常见药物可能引发Brugada模式。考虑到这种关联,心电图监测在COVID-19中变得很重要,尤其是在胸痛和发烧的患者中。正确治疗新冠肺炎患者发热是谨慎的,可避免恶性心律失常。
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引用次数: 0
The Career Planning of Female Intern Doctors and Their Specialty Preference 女实习医生职业生涯规划与专业偏好
Pub Date : 2023-01-31 DOI: 10.51200/bjms.v17i1.3786
K. Talha, Md. Ferdous Hasan, F. Selina, Hussain Ahmed, F. R. Kaiser, K. T. Erica
Internship time is a prime time for doctors to decide on their future career planning. It should be decided based on liking, work-life balance, and other factors. This was a cross-sectional study on 92 female intern doctors at Sylhet Women’s Medical College Hospital, Sylhet, Bangladesh. Information was achieved by questionnaire. Data of preferred subjects in MBBS, preferred specialty selection, influencing factor, and preferred post-graduate degree were considered variables. A western degree (37.7%) was the most preferred, followed by a fellowship (26%). The most popular specialty was general surgery (29.3%), followed by obstetrics & gynaecology (OBG). Most participants (70%) decided on their own regarding future career planning. It is important to have a well-organized future career plan during the internship. Clinical subjects were preferable to basic subjects as a specialty. Western degrees were popular over national post-graduate degrees.
实习时间是医生决定未来职业规划的黄金时间。应该根据喜好、工作与生活的平衡以及其他因素来决定。这是一项对孟加拉国Sylhet女子医学院医院92名女实习医生的横断面研究。通过问卷调查获得信息。以MBBS首选科目、首选专业选择、影响因素、首选研究生学位等数据作为变量。西方学位(37.7%)是最受欢迎的,其次是研究员(26%)。最受欢迎的专科是普外科(29.3%),其次是妇产科(OBG)。大多数参与者(70%)对未来的职业规划是自己决定的。在实习期间,有一个组织良好的未来职业规划是很重要的。临床学科优先于基础学科。西方学位比国内研究生学位更受欢迎。
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引用次数: 0
The Need for a Vaccine Against Hand, Foot, and Mouth Disease in Malaysia 马来西亚对手足口病疫苗的需求
Pub Date : 2023-01-31 DOI: 10.51200/bjms.v17i1.4285
Siat Yee Fong
Hand, foot, and mouth disease (HFMD) is a contagious viral infection, which commonly affects young children under five years of age (Yu et al., 2019). HFMD is caused by serotypes of the Enterovirus A species, particularly enterovirus 71 (EV71) and coxsackievirus A16 (CVA16), in the genus Enterovirus (Takahashi et al., 2016). Symptoms of HFMD usually include fever, sore throat and maculopapular or vesicular rashes on hands, feet and mouth, which resolve spontaneously. On the other hand, severe HFMD, which is often associated with EV71 infection, can lead to life-threatening cardiopulmonary and neurologic complications (Xu et al., 2015).
手足口病(手足口病)是一种传染性病毒感染,常见于5岁以下幼儿(Yu et al., 2019)。手足口病是由肠道病毒A种血清型引起的,特别是肠道病毒属的肠道病毒71 (EV71)和柯萨奇病毒A16 (CVA16) (Takahashi et al., 2016)。手足口病的症状通常包括发烧、喉咙痛、手、脚和口出现斑疹或水疱性皮疹,这些皮疹会自行消退。另一方面,严重的手足口病通常与EV71感染相关,可导致危及生命的心肺和神经系统并发症(Xu et al., 2015)。
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引用次数: 1
A Narrative Review on Technology-enhanced Learning in Undergraduate Medical Education 本科医学教育技术强化学习述评
Pub Date : 2022-09-30 DOI: 10.51200/bjms.v16i3.3341
May Honey Ohn, Chan Zhi Wei, Bareth Ravindran, Tamilasari Sugumarn, Khin Maung Ohn, Constance Liew, Alvin Oliver
Technology-enhanced learning (TEL) in medical education is becoming increasingly popular because it reorganizes teaching and learning dynamics, incorporates various learning media for content delivery, and provides synchronous and non-synchronousinteractions in group and individual learning. This article aimed to evaluate the usefulness of TEL models in undergraduate medical teaching. In our review of TEL in medical education, we posed three research questions to analyse its effectiveness in undergraduate medical education, which are: (a) What are the TEL modalities used in undergraduate medical education? (b) How does technology-enhanced blended learning impact students’ engagement, knowledge gain, skills acquisition, and changes in perception and attitudes? (c) Is e-learning (Moodle) more effective than other technology-assisted online learning platforms in medical education? In the review, we have seen the evolution and development of TEL; its advantages and strength over traditional learning, especially in medical education, have been reiterated. As the various modalities undergo further research and develop more sophisticatedly, TEL learning would play a bigger role as mainstream later to replace the full traditional learning. Thus, educators, institutions and policymakers must be prepared and invested in the necessary financial, time and manpower resources to embrace the coming tide, to ensure successful incorporation.
医学教育中的技术增强学习(TEL)正变得越来越受欢迎,因为它重组了教学和学习动态,结合了各种学习媒体进行内容传递,并在小组和个人学习中提供同步和非同步的互动。本研究旨在探讨教学模式在医学本科教学中的应用。在我们对医学教育中的电话教学的回顾中,我们提出了三个研究问题来分析其在本科医学教育中的有效性,这三个问题是:(a)本科医学教育中使用的电话教学模式是什么?(b)技术增强的混合式学习如何影响学生的参与、知识的获得、技能的获得以及观念和态度的变化?(c)在医学教育中,电子学习(Moodle)是否比其他技术辅助的在线学习平台更有效?在回顾中,我们看到了电讯服务的演变和发展;与传统学习相比,特别是在医学教育方面,它的优势和优势得到了重申。随着各种学习模式的进一步研究和发展,TEL学习将在以后的学习中发挥更大的主流作用,完全取代传统学习。因此,教育工作者、机构和政策制定者必须做好准备,并投入必要的财政、时间和人力资源,以迎接即将到来的浪潮,确保成功纳入。
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引用次数: 0
Modified Traditional Chinese Medicine Formula: Is It Still Effective? 中药改进型配方还有效吗?
Pub Date : 2022-09-30 DOI: 10.51200/bjms.v16i3.3887
S. Fong
Traditional Chinese medicine (TCM) is a medical system recorded over 2,000 years ago and it is making a comeback in the 21st century. Basic theories of TCM are based on the Chinese philosophy of Yin-Yang, Qi and the Five Elements (Ma et al., 2021). In TCM, balance and harmony with the environment (nature) are keys to good health and imbalances will lead to illnesses (Cheung et al., 2020). One of the approaches used by TCM practitioners to treat illnesses is the use of natural medicine derived from plants and animals (Ma et al., 2021). In practice, a combination of two or more medicinal materials (known as TCM formulas), having synergistic effects, is often used to achieve optimal therapeutic efficacy, while attenuating toxicity (Zhang et al., 2017). However, some of the materials derived from animal and plant species, such as the rhinoceros (Rhinocerotidae), tiger (Panthera tigris) and caterpillar fungus (Ophiocordyceps sinensis), which are traditionally used, are now endangered (Cheung et al., 2020). Besides, the distribution of some plant species and substances derived from these species, including Ephedra spp. (Ma Huang), Aconitum spp. (Fu Zi and Chuan Wu) and Aristolochia spp. (Mu Tong and Fang Ji) are restricted or banned in some countries due to their toxicity (Fleischer et al., 2017). Therefore, a question arises as to whether the modification of TCM formulas to eliminate these ingredients could affect their therapeutic efficacy.
传统中医(TCM)是一种有2000多年历史的医学体系,在21世纪正在卷土重来。中医的基本理论基于中国的阴阳、气和五行哲学(Ma et al., 2021)。在中医中,与环境(自然)的平衡与和谐是健康的关键,不平衡会导致疾病(Cheung et al., 2020)。中医从业者治疗疾病的方法之一是使用从植物和动物中提取的天然药物(Ma et al., 2021)。在实践中,通常使用具有协同作用的两种或两种以上药材(称为中药方剂)的组合来达到最佳治疗效果,同时降低毒性(Zhang et al., 2017)。然而,传统上使用的一些来自动植物物种的材料,如犀牛(Rhinocerotidae)、老虎(Panthera tigris)和冬虫夏草(Ophiocordyceps sinensis),现在已经濒临灭绝(Cheung et al., 2020)。此外,一些植物物种及其衍生物质,如麻黄属(Ma Huang)、乌头属(Fu Zi and Chuan Wu)、马兜铃属(Mu Tong and Fang Ji)因其毒性在一些国家被限制或禁止分布(Fleischer et al., 2017)。因此,一个问题是,修改中药配方以消除这些成分是否会影响其治疗效果。
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引用次数: 0
Gustatory Dysfunction in COVID-19: Solitary or Secondary? COVID-19患者的味觉功能障碍:孤立的还是继发性的?
Pub Date : 2022-09-30 DOI: 10.51200/bjms.v16i3.3596
A. Hossain, S. Kabir, Muhammad Tanvir Muhith, Sadia Choudhury Shimmi, M. Tanveer Hossain Parash, A. H. M. Delwar, Rafia Hossain, Firdaus Hayati, Fairrul Kadir, MOHAMMAD SAFFREE JEFFREE
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) causing Coronavirus Disease 2019 (COVID-19) commonly presented with neurological and respiratory disorders. Among the neurological symptoms, headache, myalgia, dizziness, impaired consciousness, cerebrovascular accident (CVA), olfactory dysfunction (OD), and gustatory dysfunction (GD) are typical. GD and OD have been included as new symptoms of COVID-19 infection by the World Health Organization (WHO). Taste disorders variedfrom dysgeusia to ageusia. Similarly, OD or smell disorder severity went from microsomia or hyposmia to anosmia. The merit of theseneurological disorders is an early screening criterion for a COVID-19 patient, especially where the diagnostic resources are limited. Most of the published articles demonstrate these two dysfunctions together. Our concise review aimed to determine whether GD in COVID-19 is a solitary (independent) symptom or a secondary (associated) symptom of OD. Besides, we were looking at the possible transmission pathways of SARS-CoV-2, if it can be an early diagnostic symptom, a predictor of severity, and a prognostic factor for impaired outcome. We have limited our study to publishing articles in English only. Therefore, further evaluation might be recommended to include studies published in other languages.
引起2019冠状病毒病(COVID-19)的严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)通常表现为神经和呼吸系统疾病。在神经系统症状中,头痛、肌痛、头晕、意识受损、脑血管意外(CVA)、嗅觉功能障碍(OD)和味觉功能障碍(GD)是典型的。GD和OD已被世界卫生组织(WHO)列为COVID-19感染的新症状。味觉障碍从味觉障碍到老年障碍各不相同。同样,吸毒过量或嗅觉障碍的严重程度也从小或少变为嗅觉缺失。这些神经系统疾病的优点是为COVID-19患者提供早期筛查标准,特别是在诊断资源有限的情况下。大多数已发表的文章都同时证明了这两种功能障碍。我们的简明综述旨在确定COVID-19中的GD是单独(独立)症状还是OD的继发(相关)症状。此外,我们正在研究SARS-CoV-2可能的传播途径,看它是否可以作为早期诊断症状、严重程度的预测因素和预后受损的预后因素。我们的研究仅限于发表英文文章。因此,可能建议进一步评价包括以其他语文发表的研究。
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引用次数: 0
Foreign Body Ingestion among Children of Northern Sarawak: A Retrospective Single Centre Experience 沙捞越北部儿童的异物摄入:一个回顾性的单一中心经验
Pub Date : 2022-09-30 DOI: 10.51200/bjms.v16i3.3676
Shunxing Teh, Karthigesu Aimanan, Pardheebarajan Gokilavanan, Andrew Hun Meng Quah, Khairunnisa Che Ghazali, Ahmad Junaidi Ahmad Hamidi, Aisah Munirah Wahi, Firdaus Hayati
Foreign body ingestion (FBI) is a common problem among children around the world. The management modality may differ according to the materials and clinical presentation. This study aims to assess the clinical, endoscopic, and therapeutic aspects of this FBI among children in a district hospital in northern Sarawak. A single-centre retrospective study was conducted for FBI in children of northern Sarawak from January 2018 until April 2020. A total number of 36 children were admitted during the 28 months duration with a 19:17 ratio of male:female. The children were between the age of 8 months and 10 years old with a median age of 4 ± 0.3 yrs. Coins (52%), fish bones (11%), and batteries (5%) were the most commonly ingested objects. The clinical features included asymptomatic presentation (47%), vomiting (36%), throat pain (8%), and choking sensation (8%). Routine radiological examination ensured the discovery of the FBI in 88% of the cases. Among the 36 children admitted, 19 (52%) children were managed conservatively while 17 (47%) children required endoscopic removal of foreign bodies without operative management. The length of stay in the hospital ranges from 1 day to 9 days (mean 2.52 days). FBI in children is more common at a younger age. Clinical findings depend on the shape of the ingested materials, the patient’s age, and the time of referral as they mostly could be managed conservatively. Upon failure of a conservative approach, a safe and uncomplicated removal should be performed.
异物摄入(FBI)是世界各地儿童普遍存在的问题。根据材料和临床表现,处理方式可能有所不同。本研究旨在评估沙捞越北部一家地区医院儿童的这种FBI的临床、内窥镜和治疗方面。2018年1月至2020年4月,对沙捞越北部儿童进行了一项单中心回顾性研究。在28个月的时间里,共有36名儿童入院,男女比例为19:17。患儿年龄8个月~ 10岁,中位年龄4±0.3岁。硬币(52%)、鱼骨(11%)和电池(5%)是最常被摄入的物品。临床特征包括无症状表现(47%)、呕吐(36%)、喉咙痛(8%)和窒息感(8%)。常规放射检查确保88%的病例被FBI发现。入院的36例患儿中,19例(52%)患儿采用保守治疗,17例(47%)患儿无需手术治疗,需内镜下取出异物。住院时间为1天至9天(平均2.52天)。儿童的FBI在更小的年龄更常见。临床结果取决于摄入物质的形状,患者的年龄和转诊时间,因为它们大多可以保守处理。保守入路失败后,应进行安全、简单的拔除。
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引用次数: 0
Comparing the Ease of Intubation between C-MAC, McGrath, and Conventional Macintosh Laryngoscope in a Simulated Difficult Airway of a Laerdal Mannequin 比较C-MAC喉镜、McGrath喉镜和传统Macintosh喉镜在模拟困难气道中的插管便利性
Pub Date : 2022-09-30 DOI: 10.51200/bjms.v16i3.3706
T. Kumaravadivel Dharmalingam, Koay Boon Xin, Koeh Shao Keong, R. K. Muniandy
Tracheal intubation is an essential skill for doctors. Tracheal intubation is done in patients with questionable airway patency, poor respiratory drive, hypercarbia, or hypoxia. The objective of this study was to compare the ease of tracheal intubation using MacintoshLaryngoscopes, C-MAC, and McGrath on a simulated difficult airway mannequin. The rationale of the study was to identify the easiest device to use for tracheal intubation. This randomized clinical trial was done at the Teluk Intan Hospital, Perak, Malaysia, from March 2020 to February 2021. Sixty-five medical officers participated in this study. The results showed that the mean time for tracheal intubation was significantly shorter when the participants were using the C-MAC than the conventional direct laryngoscope and McGrath. (C-MAC: 20.8 seconds, Direct Laryngoscope: 27.7 seconds, McGrath: 34.6 seconds) The results showed that C-MAC andMcGrath had a better first-attempt success rate than conventional direct laryngoscopes. C-MAC scored the highest first-attempt success rate, followed by McGrath. (95% compared to 83%) Regarding Cormack-Lehane grading, the C-MAC device showed a better view than McGrath and Direct Laryngoscope. The preferred device by medical officers for tracheal intubation was the C-MAC. (45% compared to other devices) In conclusion, the C-MAC device was superior in first attempt success rate and was the most preferred device compared to McGrath and direct laryngoscope. However, using the C-MAC device must be accompanied by adequate training and practice. 
气管插管是医生的一项基本技能。气管插管适用于可疑气道通畅、呼吸驱动差、高碳或缺氧的患者。本研究的目的是比较在模拟困难气道人体模型上使用macintosh喉镜、C-MAC和McGrath进行气管插管的便利性。这项研究的基本原理是确定最容易用于气管插管的设备。这项随机临床试验于2020年3月至2021年2月在马来西亚霹雳州的Teluk Intan医院进行。65名医务人员参与了这项研究。结果表明,使用C-MAC时气管插管的平均时间明显短于常规直接喉镜和McGrath。(C-MAC: 20.8秒,直接喉镜:27.7秒,McGrath: 34.6秒)结果表明,C-MAC和McGrath的首次尝试成功率高于常规直接喉镜。C-MAC的第一次尝试成功率最高,其次是McGrath。(95%比83%)关于Cormack-Lehane分级,C-MAC装置比McGrath和直接喉镜显示更好的视野。医务人员首选的气管插管设备是C-MAC。(45%)综上所述,与McGrath和直接喉镜相比,C-MAC装置的首次尝试成功率更高,是最受欢迎的设备。但是,使用C-MAC器械必须经过充分的培训和实践。
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引用次数: 0
Factors influencing Anopheles larval habitats in Kudat District, Sabah, Malaysia 马来西亚沙巴州古达区按蚊幼虫生境影响因素
Pub Date : 2022-09-30 DOI: 10.51200/bjms.v16i3.3336
Wilfredo E Aure, Nelia P. Salazar, Tock Hing Chua
A longitudinal survey of Anopheles larval habitats was conducted in adjoining areas of Kampung Marabahai, Nangka, Paradason and Tuboh in Kudat District, Sabah from May 2015 to April 2016. Ninety-five out of 368 breeding habitats sampled were positive for Anopheles larvae. The significant physicochemical factors that were associated with the presence of Anopheles larvae were: turbidity, shadiness, presence of water vegetation, surface area, temperature, pH (negative log of the hydrogen ion concentration), and Electrical Conductivity (EC). Thus, this paper highlighted the physicochemical characteristic of larval habitats of Anopheles mosquito with emphasis on An. balabacensis, the vector of Plasmodium knowlesi malaria, could be targeted for surveillance studies and control interventions.
2015年5月至2016年4月,在沙巴州古达区Kampung Marabahai、Nangka、Paradason和Tuboh邻近地区对按蚊幼虫生境进行了纵向调查。在368个按蚊孳生地中,95个按蚊幼虫呈阳性。与按蚊幼虫存在相关的重要理化因素有:浑浊度、阴影、水体植被、表面积、温度、pH(氢离子浓度的负对数)和电导率(EC)。因此,本文重点介绍了按蚊幼虫生境的理化特征,并以安氏按蚊为研究对象。作为诺氏疟原虫疟疾的媒介,balabacensis可以作为监测研究和控制干预措施的目标。
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引用次数: 0
Descriptive Profile of Urolithiasis Cases in a Tertiary Hospital in Sabah 沙巴一家三级医院尿石症病例描述
Pub Date : 2022-05-31 DOI: 10.51200/bjms.vi.3310
Jaspreet Cheema, S. Thevarajah
Urolithiasis is a common urological problem in Malaysia. Stones can be formed by precipitation or crystallization of minerals and urinary constituents. It is a multifactorial, recurrent disease distributed worldwide with a trend of increasing incidence. This study aims to describe the characteristics of patients with urolithiasis in a tertiary centre in Sabah. Patients seen in the urology clinic or inpatient ward in the Department of Urology, Hospital Queen Elizabeth, Sabah, who had urolithiasis confirmed on plain CT KUB were reviewed. Demographic data regarding age, gender, race, address, and BMI were recorded. Details regarding fluid intake and family history of urolithiasis associated with medical conditions like diabetes, hypertension, and gout were collected during the interview with the patient. Routine urine and blood investigations for urolithiasis were performed, and results with CT scan findings were recorded in a data collection sheet. A total of 300 patients with urolithiasis were reviewed. The median age was 54 years, with similar gender distribution. BMI above normal was found in 69% of participants, and 55% had underlying hypertension. The highest incidence was seen in the Kadazan-Dusun population. Those who consume < 2 L/day of fluid also had a higher frequency of urolithiasis. 60.6% of stones were unilateral, whereas 43.7% were found to be renal. There were 39.7% of patients who had CKD stage 2. The mean Hounsfield unit of stones was 1,091. In conclusion, urolithiasis is a common problem worldwide, and it is apparent that its burden on the healthcare system is increasing. These findings will help better understand local clinical characteristics to prevent and reduce morbidity and mortality by urolithiasis.
尿石症是马来西亚常见的泌尿系统疾病。结石可由矿物质和尿液成分的沉淀或结晶形成。它是一种多因素的复发性疾病,分布在世界各地,发病率呈上升趋势。本研究旨在描述沙巴三级中心尿石症患者的特征。我们回顾了在沙巴伊丽莎白女王医院泌尿科门诊或住院病房就诊的经KUB平片CT确诊的尿石症患者。记录年龄、性别、种族、住址和体重指数等人口统计数据。在与患者的访谈中收集了有关液体摄入量和尿石症家族史(如糖尿病、高血压和痛风)的详细信息。对尿石症进行尿常规和血常规检查,并将结果与CT扫描结果记录在数据收集表中。本文回顾了300例尿石症患者。年龄中位数为54岁,性别分布相似。69%的参与者BMI高于正常水平,55%的参与者有潜在的高血压。发病率最高的是Kadazan-Dusun人群。每天饮水量< 2升的人患尿石症的几率也更高。60.6%为单侧结石,43.7%为肾脏结石。39.7%的患者为CKD 2期。结石的平均亨斯菲尔德单位是1091。总之,尿石症在世界范围内是一个普遍的问题,很明显,它对卫生保健系统的负担正在增加。这些发现将有助于更好地了解当地的临床特征,以预防和降低尿石症的发病率和死亡率。
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引用次数: 0
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Borneo Journal of Medical Sciences (BJMS)
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