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Meaning in Medical Ethics 医学伦理学意义
Pub Date : 2018-09-24 DOI: 10.31579/2639-4162/007
Richard Boudreau
Medical ethics is a system of moral principles that applies values to the practice of clinical medicine and to scientific research. They are based on a set of values that professionals can refer to in the event that they are in conflict or are confused. The values include: beneficence, non-maleficence, autonomy, justice, veracity, dignity. The code of ethics is based on the understanding of the goals of medicine dating back to the 5th century B.C. and Hippocrates. By 1847, the code of ethics was based greatly on Thomas Percival's work. He was an English physician-philosopher and wrote a code of medical ethics for hospitals in 1803.
医学伦理学是将价值观应用于临床医学实践和科学研究的道德原则体系。它们基于一套价值观,专业人员在遇到冲突或困惑时可以参考这些价值观。这些价值观包括:仁慈、无害、自主、公正、诚实、尊严。道德准则是基于对医学目标的理解,这可以追溯到公元前5世纪和希波克拉底。到1847年,道德准则在很大程度上是基于托马斯·珀西瓦尔的工作。他是一位英国医生兼哲学家,并于1803年为医院撰写了医学伦理准则。
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引用次数: 0
Improving Nutritional Status of Malnourished Bedridden Patient Diagnosed with Deep Vein Thrombosis and Pulmonary Embolism: A Case Study Approach 改善营养不良的深静脉血栓形成和肺栓塞患者营养状况的个案研究
Pub Date : 2018-09-03 DOI: 10.31579/2639-4162/001
Adikari Amnt
Malnutrition is common among hospitalized bed ridden patients. Nutritional management of hospitalized patients is a necessity in order to improve their nutritional status and disease conditions. The objectives of nutritional management of malnourished bedridden patient diagnosed with deep vein thrombosis and pulmonary embolism were to improve nutritional status of the patient through gradual provision of calorie and protein intake, to improve body protein status and control muscle wasting. Nutritional status was assessed by anthropometric, biochemical, clinical and dietary information. SGA was used to assess the malnutrition status of the patient. Since the patient was severely malnourished, she was fed with NG feeds followed by PEG feeds by gradually increasing calorie and protein up to the target level mainly through nutritional supplements for the one and half months of hospital stay. Patient’s serum protein, albumin levels and muscle mass were improved. According to the SGA, the patient was at normal/ well-nourished condition after nutrition management. Dietary management incorporating nutrition supplements indicated improvement of nutritional status of severely malnourished bedridden patient.
营养不良在卧床不起的住院病人中很常见。住院患者的营养管理是改善其营养状况和疾病状况的必要条件。诊断为深静脉血栓形成和肺栓塞的营养不良卧床患者的营养管理目标是通过逐渐提供热量和蛋白质摄入来改善患者的营养状况,改善身体蛋白质状况并控制肌肉萎缩。营养状况通过人体测量、生物化学、临床和饮食信息进行评估。SGA用于评估患者的营养不良状况。由于患者严重营养不良,在住院的一个半月内,主要通过营养补充剂将热量和蛋白质逐渐增加到目标水平,给她喂食NG饲料,然后喂食PEG饲料。患者的血清蛋白、白蛋白水平和肌肉质量得到改善。根据SGA,患者在营养管理后处于正常/营养良好的状态。结合营养补充剂的饮食管理表明,严重营养不良的卧床不起患者的营养状况有所改善。
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引用次数: 0
The Underrecognized Cardiac Manifestation of Hypereosinophilic Syndrome 高嗜酸性粒细胞综合征未被充分认识的心脏表现
Pub Date : 2018-09-03 DOI: 10.31579/2639-4162/002
A. Malhotra
Hypereosinophilic syndrome (HES) is a rare systemic disease in which cardiac manifestations are the leading cause of morbidity and mortality. HES involvement of the heart can often clinically mimic acute coronary syndrome (ACS) with the patient undergoing repeat cardiac catheterizations when no conclusive diagnosis is arrived at, and no effective treatment is suggested to alleviate recurrent symptoms of chest discomfort. Here we present an elusive case of eosinophilic myocarditis (EM) and advocate that a detailed review of history as well as obtaining all medical records be done to avoid unnecessary and repeated invasive investigations in order to provide safe, cost effective, and efficient care for our patients.
高嗜酸性粒细胞综合征(HES)是一种罕见的全身性疾病,其心脏表现是发病率和死亡率的主要原因。HES累及心脏在临床上常常可模拟急性冠状动脉综合征(ACS),患者在没有明确诊断的情况下进行多次心导管插入术,并且没有有效的治疗方法来缓解反复出现的胸部不适症状。在此,我们报告一个难以理解的嗜酸性心肌炎(EM)病例,并提倡对病史进行详细的回顾,并获得所有的医疗记录,以避免不必要的和重复的侵入性检查,以便为我们的患者提供安全、经济、高效的护理。
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引用次数: 0
Are Platelet Aggregation Tests the Best Way to Assess New Drugs for Arterial Disease 血小板聚集试验是评估动脉疾病新药的最佳方法吗
Pub Date : 2018-09-03 DOI: 10.31579/2639-4162/003
Mark I. M. Noble
Over many years, laboratory testing of platelet aggregability have been carried out in attempts to develop drugs that would prevent thrombosis in arteries. The problems encountered included the question of methodology. Blood samples have to be anticoagulated in order to study the platelets. Anti-coagulation with citrate and tests on derived platelet rich plasma did not correlate at all well with thrombus growth in the stenosed coronary arteries of experimental animals and citrate removes the calcium ions which are vital for platelet function. Anticoagulation with heparin also interfered with platelet function, so that now, hirudins are the preferred anticoagulant. However it was observed that if, instead of stimulating platelet aggregation with adrenaline or ADP, serotonin was applied to the preparation, very little aggregation took place in spite of serotonin 5HT2A antagonists being the most potent inhibitors of thrombus growth in experimental animals. Another indicator that primary platelet agggregation is not a predictor of in vivo efficacy was the finding that 5HT2A antagonism inhibited aggregate growth. In a stenosed artery the platelets are activated by increased shear stress and blood turbulence with release of platelet serotonin causing positive feedback activation of more platelets. At present, there does not seem to be a bench in vitro test that accurately predicts in vivo efficacy in stenosed artery occlusive thrombosis.
多年来,实验室对血小板聚集性进行了测试,试图开发防止动脉血栓形成的药物。所遇到的问题包括方法问题。为了研究血小板,血液样本必须是抗凝的。柠檬酸盐抗凝和衍生的富血小板血浆试验与实验动物狭窄冠状动脉血栓生长完全不相关,柠檬酸盐去除对血小板功能至关重要的钙离子。肝素抗凝也会干扰血小板功能,因此水蛭素是目前首选的抗凝剂。然而,我们观察到,如果不使用肾上腺素或ADP刺激血小板聚集,而将5 -羟色胺应用于制备中,尽管5 -羟色胺5HT2A拮抗剂是实验动物中最有效的血栓生长抑制剂,但几乎没有发生聚集。原发性血小板聚集不是体内疗效预测因子的另一个指标是发现5HT2A拮抗剂抑制聚集生长。在狭窄的动脉中,血小板被增加的剪切应力和血液湍流激活,血小板5 -羟色胺的释放导致更多血小板的正反馈激活。目前,似乎还没有一种体外实验能准确预测狭窄动脉闭塞性血栓形成的体内疗效。
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引用次数: 0
Acute polyarthritis revealing celiac disease of the elderly 揭示老年人乳糜泻的急性多发性关节炎
Pub Date : 2018-09-03 DOI: 10.31579/2639-4162/004
Bouomrani S
Introduction: Celiac disease (CD) is an autoimmune disease that typically occurs in childhood and young age. Late-onset forms (after 60 years) are rare and often underestimated in current medical practice, as is joint damage during this disease. We report an original case of CD in an elderly patient revealed by acute polyarthritis. Observation: A 62-year-old patient with no significant pathological history was explored for acute polyarthritis of both large and small joints. The physical examination noted synovitis of the hands and wrists without articular deformities, and a marked mucocutaneous pallor. The biology revealed a microcytic anemia at 8 g/dl with stigmas of malabsorption (low cholesterol and hypocalcemia). No inflammatory syndrome was noted. Joint X-rays were without abnormalities. Immunological tests for chronic inflammatory rheumatisms were negative. Gastroduodenal fibroscopy was performed and histological examination of duodenal biopsies showed diffuse villous atrophy with marked inflammatory infiltrate. Anti- endomysium and anti-transglutaminase antibodies were positive confirming the diagnosis of CD. Under gluten-free diet, the evolution was favorable with totally disappearance of articular signs. Conclusion: Joint manifestations during CD are rare. The revealing forms are exceptional and can make a differential diagnosis with chronic inflammatory rheumatism, in particular that associations with CD was described. CD deserves to be evoked in front of any unexplained arthritis of the elderly, even without any specific digestive symptomatology of this disease.
引言:腹腔疾病(CD)是一种自身免疫性疾病,通常发生在儿童和青少年。晚发型(60年后)在目前的医疗实践中很罕见,而且经常被低估,这种疾病期间的关节损伤也是如此。我们报告了一例老年急性多关节炎患者CD的原始病例。观察:一名62岁的无明显病理史的患者被诊断为大小关节急性多关节炎。体格检查发现手和手腕的滑膜炎没有关节畸形,并且有明显的粘膜皮肤苍白。生物学显示,8 g/dl的微细胞性贫血伴有吸收不良的柱头(低胆固醇和低钙血症)。未发现炎症综合征。关节X光检查无异常。慢性炎症性风湿病的免疫测试呈阴性。进行了胃十二指肠纤维镜检查,十二指肠活检的组织学检查显示弥漫性绒毛萎缩和明显的炎症浸润。抗endomysium和抗谷氨酰胺转胺酶抗体阳性,证实CD的诊断。在无麸质饮食下,进化有利,关节体征完全消失。结论:CD期间的关节表现是罕见的。揭示的形式是特殊的,可以对慢性炎症性风湿病进行鉴别诊断,特别是与CD的相关性。CD值得在任何无法解释的老年关节炎面前被唤起,即使没有任何特定的消化系统症状。
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引用次数: 0
Case Report: A rare association between SLE and Acute Lymphatic Leukemia SLE与急性淋巴细胞白血病的罕见关联病例报告
Pub Date : 2018-07-19 DOI: 10.31579/2639-4162/011
P. Sasidharan
A 30-year-old housewife with past history of acute lymphoblastic leukemia 12 years back, still in remission, was admitted with polyarthritis of 2 months duration. She was evaluated and found to have SLE with positive ANA and Anti ds DNA which were strongly positive.
一位30岁的家庭主妇,12年前有急性淋巴细胞白血病病史,仍处于缓解期,因多关节炎入院,持续时间为2个月。对她进行了评估,发现她患有SLE,ANA和抗-ds DNA呈阳性,呈强阳性。
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引用次数: 0
Prevention of cancer in primary care: principles and practices 初级保健中预防癌症的原则和实践
Pub Date : 2018-07-19 DOI: 10.31579/2639-4162/010
L. Döbrőssy
This paper focuses on what the primary care team – physicians and praxis nurses – can do to prevent the most common non-communicable diseases, particularly cancer. The most basic concepts underlying the preventive practice in primary care are summarized.
这篇论文的重点是初级保健团队——医生和实习护士——可以做些什么来预防最常见的非传染性疾病,尤其是癌症。概述了初级保健预防实践的最基本概念。
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引用次数: 0
Research Article: Impact of Cooking Fuel Choices on Maternal Lung Functions in Selected Rural and Urban Areas of Copperbelt Province, Zambia 研究论文:赞比亚铜带省部分农村和城市地区烹饪燃料选择对产妇肺功能的影响
Pub Date : 2018-07-11 DOI: 10.31579/2639-4162/012
David Mulenga
Background: Considering the respiratory health risk of exposure to biomass cooking fuel emissions, this study was conducted to elucidate the relationship between cooking fuel choices and declined pulmonary function in rural and urban population in the Copperbelt Province of Zambia. Methods: We carried out a cross-sectional study of 1,170 healthy nonsmoking pregnant women from Masaiti and Ndola predominantly using biomass fuel for cooking. Questionnaire based data was acquired along with standardized measures of lung function. MIR Spirobank G (Italy) was used in spirometry based on American Thoracic Standards. Results: The present study found that over two thirds (69.2%) of pregnant women in the study population use biomass for cooking and only 12.4 % use electricity only. Declined lung function was found to be statistically significantly associated with cooking fuel choices (p – value 0.005) and a weak association was observed with gravida at a p-value of 0.056. Pregnant women using crop residues as cooking fuel were two times more likely to have a declined lung function [AOR 2.33 (1.27, 4.30)] compared with pregnant women using mixed fuel type (biomass and electricity) and those using electricity only were 57% less likely to have a declined lung function [AOD 0.43 (0.26, 0.69)]. Conclusion: Use of biomass for cooking among pregnant women is a strong determinant of declined lung function. Interventions to improve maternal respiratory health outcomes in Zambia and other countries in sub-Saharan Africa should involve making cleaner cooking fuel energy options available and accessible by ordinary women from both rural and urban areas.
背景:考虑到接触生物质烹饪燃料排放的呼吸健康风险,本研究旨在阐明赞比亚铜带省农村和城市人口烹饪燃料选择与肺功能下降之间的关系。方法:我们对来自Masaiti和Ndola的1170名主要使用生物质燃料烹饪的健康非吸烟孕妇进行了横断面研究。采集了基于问卷的数据以及肺功能的标准化测量。MIR Spirobank G(意大利)用于基于美国胸科标准的肺活量测定。结果:本研究发现,研究人群中超过三分之二(69.2%)的孕妇使用生物质做饭,只有12.4%的孕妇只使用电力。研究发现,肺功能下降与烹饪燃料的选择有统计学意义(p值0.005),而与妊娠率的相关性较弱,p值为0.056。与使用混合燃料(生物质和电力)的孕妇相比,使用作物残渣作为烹饪燃料的孕妇肺功能下降的可能性是使用混合燃料的孕妇的两倍[AOR 2.33(1.27,4.30)],仅使用电力的孕妇肺功能下降的可能性低57%[AOD 0.43(0.26,0.69)]肺功能下降的决定因素。赞比亚和撒哈拉以南非洲其他国家为改善孕产妇呼吸健康状况而采取的干预措施应包括为农村和城市地区的普通妇女提供更清洁的烹饪燃料能源选择。
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引用次数: 0
Hiding Shame in Science and Scholarship 在科学和学术中隐藏羞耻
Pub Date : 2018-07-11 DOI: 10.23880/pprij-16000148
T. Scheff
Modern societies tend to ignore emotion, especially the emotion of shame. But for that reason, shame especially may become important to understand. Beginning with Norbert Elias and Helen B.
现代社会倾向于忽视情感,尤其是羞耻感。但正因为如此,理解羞耻感可能变得尤为重要。从诺伯特·伊莱亚斯和海伦·B。
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引用次数: 0
Short Communication: Role of Leadership in Doctor-Patient Relationship & Execution on Patient’s Case Management in Primary Care 短沟通:领导在医患关系中的作用及在初级保健患者病例管理中的执行
Pub Date : 2018-07-11 DOI: 10.31579/2639-4162/013
S. Naeem
Primary care physicians (PCP) needs to plan, organize, implement, and evaluate as care director and coordinator. In primary care there is need to implement leadership model in health sector and medicine. Transformational leadership can be described as style of leadership which is appropriate for health sector. It is alike to the approach which is patient centered. Case management must be well organized, prepared, arranged and described as per needs of patient. The same must be agreed and implemented with suitable individual roles. Leaders are required to do numerous aspects linked to management, managerial and decision making process to carry out the requisite actions. Same process and procedures are also required be completed by Primary care physicians for achievement of patient’s targeted administration, supervision and management. Such happenings and actions contain from preparation, planning, development till structuring networks. Primary care physicians are anticipated to possess transformational leadership capabilities and to assist their performance in role of care coordinators. This all can be attained through integrated, holistic, continuous, comprehensive approach and by building relations with all stakeholders.
初级保健医生(PCP)需要作为护理主任和协调者进行计划、组织、实施和评估。在初级保健方面,需要在卫生部门和医药领域实施领导模式。变革型领导可以被描述为一种适合卫生部门的领导风格。这和以病人为中心的方法是相似的。病例管理必须根据患者的需要进行良好的组织、准备、安排和描述。同样的,必须由合适的个人角色来商定和实施。领导者需要做与管理、管理和决策过程相关的许多方面的工作,以开展必要的行动。初级保健医生也需要完成相同的过程和程序,以实现对患者的针对性管理、监督和管理。这些事件和行动包括从准备、计划、发展到构建网络。初级保健医生被期望拥有变革的领导能力,并协助他们在护理协调员的角色表现。这一切都可以通过综合、全面、持续和全面的方法以及与所有利益攸关方建立关系来实现。
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引用次数: 0
期刊
General medicine and clinical practice
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