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Right Lower Sleeve Lobectomy: Detailed Technique and Perioperative Patient Management. 右下袖状肺叶切除术:详细技术和围手术期患者管理。
Hidetoshi Inoue, Takuma Tsukioka, Nobuhiro Izumi, Kantaro Hara, Satoshi Suzuki, Takuya Tanimura, Noritoshi Nishiyama

Purpose: This report reviews our experience with right lower sleeve lobectomy and describes our technique and approach to perioperative patient management.

Methods: We retrospectively reviewed 11 patients who underwent right lower sleeve lobectomy for lung cancer. Surgical techniques and perioperative management were also investigated.

Results: Bronchoplasty was performed using 4-0 absorbable monofilament sutures. The deepest portion was anastomosed using continuous sutures; interrupted sutures were used for the more superficial portions. The truncus intermedius and right middle lobe bronchus should be anastomosed in a natural position. Anastomosis patency was confirmed using intraoperative bronchoscopy. Separation of the right upper and middle lobes and pericardiotomy at the inferior edge of the superior pulmonary vein are useful for mobilizing the right middle lobe. Death during hospitalization and treatment-related death did not occur. One patient developed pneumonia, and another developed a bronchopleural fistula.

Conclusion: We reported our technique of right lower sleeve lobectomy and our approach to perioperative patient management. Sharing knowledge is essential to completing this rare surgery.

目的:本报告回顾了我们在右下袖状肺叶切除术方面的经验,并介绍了我们的技术和围手术期患者管理方法:方法:我们回顾性分析了 11 例接受右下袖状肺叶切除术的肺癌患者。方法:我们回顾了 11 例因肺癌接受右下袖状肺叶切除术的患者,并对手术技术和围手术期管理进行了调查:结果:使用 4-0 可吸收单丝缝线进行了支气管成形术。最深的部分采用连续缝合;较浅的部分采用间断缝合。中间截管和右中叶支气管应在自然位置吻合。吻合口的通畅性由术中支气管镜确认。分离右肺上叶和中叶以及在肺上静脉下缘进行心包切开术有助于移动右肺中叶。没有发生住院期间死亡和与治疗相关的死亡。一名患者出现肺炎,另一名患者出现支气管胸膜瘘:我们报告了右下袖状肺叶切除术的技术和围手术期患者管理方法。分享知识对于完成这种罕见手术至关重要。
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引用次数: 0
Robot-Assisted Correction of a Supra-Long Tracheal Stenosis Using C-Type Nickel-Titanium Alloy Exterior Stenting and Suspension Fixation Technique: A Case Report. 机器人辅助下使用 C 型镍钛合金外支架和悬吊固定技术矫正超长气管狭窄:病例报告。
Jingquan Han, Xi Yan, Hongwei Cui, Hang Zhang, Bei Lu, Jinzhi Xu

T-tubes and airway stents are commonly used but have limited effectiveness and frequent complications. A 50-year-old male patient presented with severe tracheal stenosis, affecting an 8.7 cm length of the airway. We employed an innovative approach known as external suspension fixation of tracheal stent using robotic assistance. This method involves surgically attaching the stent to the exterior of the trachea to provide support and stabilize the softened or collapsed tracheal segments. We designed a C-shaped nickel-titanium alloy exterior stent and successfully fixed it using robotic assistance. This intervention effectively restored tracheal function and led to a favorable postoperative recovery. The technique does not affect tracheal membrane function or airway mucociliary clearance. It could potentially be considered as a new option for treating long-segment benign tracheal softening or collapse.

T 型管和气道支架是常用的气道支架,但效果有限且经常出现并发症。一名 50 岁的男性患者患有严重的气管狭窄,气管长度达 8.7 厘米。我们采用了一种创新方法,即利用机器人辅助进行气管支架外悬吊固定。这种方法是通过手术将支架固定在气管外部,为软化或塌陷的气管段提供支撑和稳定。我们设计了一种 C 型镍钛合金外部支架,并在机器人辅助下成功将其固定。这一干预措施有效地恢复了气管功能,术后恢复良好。该技术不影响气管膜功能和气道粘膜纤毛清除。它有可能被视为治疗长段良性气管软化或塌陷的一种新选择。
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引用次数: 0
Curved Axillary Incision with Video-Assisted Thoracoscopic Surgery: An Alternative Approach for Teenage Female with Large Apical Chest Wall Tumor. 腋窝弧形切口与视频辅助胸腔镜手术:为患有巨大胸壁顶端肿瘤的少女提供另一种方法
Ryoichiro Doi, Hiromi Ichikawa, Keitaro Matsumoto, Koichi Tomoshige, Ryusuke Machino, Shinji Okano, Takeshi Nagayasu

Primary chest wall tumors are rare, their common clinical features are not well known, and surgical resection remains the main treatment. Apical chest wall tumors require large skin incisions and dissection of the chest wall muscles, making it difficult to maintain cosmetic appearance, respiratory function, and support of the upper extremity. There are few treatment options and no studies have reported on thoracotomy that spares muscles and preserves cosmetic superiority. However, in benign chest wall tumors in young patients, it is necessary to consider radicality, cosmetic superiority, and muscle sparing. We used a combined axillary incision and thoracoscopic approach to treat a massive myxoid neurofibroma at the apical chest wall in a 14-year-old female and were able to preserve the chest wall, upper limb function, and cosmetic aspects. This report provides a detailed description of the combined axillary incision and thoracoscopic approach for apical chest wall tumors.

原发性胸壁肿瘤非常罕见,其常见的临床特征并不为人所知,手术切除仍是主要的治疗方法。胸壁顶部肿瘤需要大的皮肤切口和胸壁肌肉解剖,因此很难保持美观、呼吸功能和上肢支撑。目前可供选择的治疗方法很少,也没有关于胸廓切开术既能保留肌肉又能保持美观的研究报告。然而,对于年轻患者的良性胸壁肿瘤,有必要考虑根治性、美观性和保留肌肉。我们采用腋窝切口和胸腔镜联合方法治疗了一名 14 岁女性胸壁顶端的巨大肌样神经纤维瘤,并保留了胸壁、上肢功能和美观。本报告详细介绍了腋窝切口和胸腔镜联合方法治疗胸壁顶端肿瘤。
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引用次数: 0
Comparison of Prognosis for Lung Transplantation between Older and Younger Donors: A Systematic Review and Meta-Analysis Based on Cohort Studies. 老年捐献者与年轻捐献者肺移植预后的比较:基于队列研究的系统性回顾和荟萃分析
Yongkang Di, Rongrong Fu, Zhiyi Xiang, Huiwen Sun, Min Dai, Qiufeng Zhang, Yuexiu Si

Purpose: This meta-analysis aimed to compare the prognosis of lung transplantation recipients based on donor age.

Methods: A detailed search was performed in PubMed, Embase, Web of Science, and the Cochrane Library for cohort studies on lung transplantation. The prognosis of lung transplant recipients was investigated based on the donor age, with the primary outcomes being 1-year overall survival (OS), 3-year OS, 5-year OS, and 5-year chronic lung allograft dysfunction (CLAD)-free survival.

Results: This meta-analysis included 10 cohort studies. Among the short-term outcomes, the older donor group demonstrated no significant difference from the young donor group in primary graft dysfunction within 72 hours, use of extracorporeal membrane oxygenation, length of ventilator use, and intensive care unit hours. However, a longer hospital stay was associated with the older donor group. In terms of long-term outcomes, no difference was found between the two groups in 1-year OS, 3-year OS, and 5-year OS. Notably, patients with older donors exhibited a superior 5-year CLAD-free survival.

Conclusions: The results of this meta-analysis indicate that older donors are not inferior to younger donors in terms of long-term and short-term recipient outcomes. Lung transplantation using older donors is a potential therapeutic option after rigorous evaluation.

目的:本荟萃分析旨在根据供体年龄比较肺移植受者的预后:方法:在 PubMed、Embase、Web of Science 和 Cochrane 图书馆中详细检索了有关肺移植的队列研究。根据供体年龄调查肺移植受者的预后,主要结果为1年总生存期(OS)、3年OS、5年OS和5年无慢性肺异体功能障碍(CLAD)生存期:这项荟萃分析包括 10 项队列研究。在短期结果中,老年捐献者组与年轻捐献者组在72小时内初次移植物功能障碍、体外膜肺氧合的使用、呼吸机使用时间和重症监护室使用时间方面无明显差异。不过,老年捐献者组的住院时间更长。在长期预后方面,两组患者的 1 年 OS、3 年 OS 和 5 年 OS 均无差异。值得注意的是,年长供体组患者的5年无CLAD生存率更高:这项荟萃分析的结果表明,就长期和短期受者预后而言,老年供体并不比年轻供体差。经过严格评估,使用老年供体进行肺移植是一种潜在的治疗选择。
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引用次数: 0
The Below-the-Knee Approach to Percutaneous Mechanical Thrombectomy for Lower Extremity Deep Venous Thrombosis: A Retrospective Single-Centre, Single-Arm Study. 经皮机械取栓术治疗下肢深静脉血栓的膝下入路:单中心、单臂回顾性研究。
Wenrui Li, Lei Jin, Hai Feng, Xueming Chen, Zhiwen Zhang

Purpose: The objective of this study was to evaluate the safety, efficacy, and feasibility of percutaneous mechanical thrombectomy (PMT) through a below-the-knee (BTK) approach for acute lower extremity deep venous thrombosis (DVT).

Methods: A retrospective review of DVT patients treated with PMT by the BTK approach at our center from April 2022 to August 2023 was performed. Their preoperative demographics, intraoperative data, and postoperative outpatient outcomes were analyzed.

Results: A total of 12 patients (67% men; mean age, 63 years) met the inclusion criteria. The BTK approach was successfully achieved in all patients through the posterior tibial vein (n = 1), anterior tibial vein (n = 2), and peroneal vein (n = 9). PMTs were achieved in 11 (92%) patients. Successful lysis (grade II and grade III lysis) was achieved in all patients with PMT. Four (33%) patients had residual venous occlusion over the popliteal vein. No intraoperative complications or bleeding events occurred in any of the patients.

Conclusion: PMT via BTK puncture seems to be a safe and effective approach for treating lower extremity DVT. It is reserved for highly select patients with a low risk of bleeding and is performed at centers that have experience with this procedure.

目的:本研究旨在评估通过膝下(BTK)方法进行经皮机械取栓术(PMT)治疗急性下肢深静脉血栓(DVT)的安全性、有效性和可行性:本中心对2022年4月至2023年8月期间通过BTK方法接受经皮机械取栓术治疗的深静脉血栓患者进行了回顾性研究。分析了他们的术前人口统计学、术中数据和术后门诊结果:共有12名患者(67%为男性,平均年龄63岁)符合纳入标准。所有患者均通过胫后静脉(1 例)、胫前静脉(2 例)和腓肠静脉(9 例)成功实施了 BTK 方法。有 11 名患者(92%)实现了 PMT。所有 PMT 患者均成功溶解(II 级和 III 级溶解)。4名患者(33%)的腘静脉有残余静脉闭塞。所有患者均未发生术中并发症或出血事件:结论:通过 BTK 穿刺进行 PMT 似乎是治疗下肢深静脉血栓的一种安全有效的方法。结论:通过 BTK 穿刺进行 PMT 似乎是治疗下肢深静脉血栓形成的一种安全有效的方法,它只适用于经过严格筛选且出血风险较低的患者,并应在有经验的中心进行。
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引用次数: 0
Prospective Observation Study for Primary Spontaneous Pneumothorax: Incidence of and Risk Factors for Postoperative Neogenesis of Bullae. 原发性自发性气胸的前瞻性观察研究:术后肺泡新生的发生率和风险因素。
Chihiro Furuta, Motoki Yano, Yuka Kitagawa, Ryotaro Katsuya, Naoki Ozeki, Takayuki Fukui

Purpose: Details of the neogenesis of bullae (NOB), which causes recurrent primary spontaneous pneumothorax (PSP) following bullectomy, have not been reported and risk factors for NOB remain unclear. We aimed to clarify the details of NOB.

Methods: We conducted a prospective study using three computed tomography (CT) examinations performed 6, 12, and 24 months after bullectomy to identify the incidence of and risk factors for NOB. We enrolled 50 patients who underwent bullectomy for PSP.

Results: After excluding 11 patients who canceled the postoperative CT examination at 6 months after bullectomy, only 39 patients were analyzed. The incidence of NOB at 6, 12, and 24 months after bullectomy was 38.5%, 55.2%, and 71.2%, respectively. The rate of NOB in the operated lung was almost 2 times higher than that in the contralateral nonoperative lung. Male sex, multiple bullae on preoperative CT, long stapling line (≥7 cm), deep stapling depth (≥1.5 cm), and heavier resected sample (≥5 g) were suggested to be risk factors for NOB.

Conclusions: We recognized a high incidence of postoperative NOB in PSP patients. Bullectomy itself seems to promote NOB. Postoperative NOB occurs frequently, especially in patients who require a large-volume lung resection with a long staple line.

目的:鼓室新生(NOB)是鼓室切除术后导致原发性自发性气胸(PSP)复发的原因之一,但关于NOB的详细情况尚未见报道,而且NOB的风险因素仍不明确。我们的目的是澄清 NOB 的详细情况:我们进行了一项前瞻性研究,利用鼓室切除术后 6、12 和 24 个月进行的三次计算机断层扫描(CT)检查来确定 NOB 的发生率和风险因素。我们招募了 50 名因 PSP 而接受球囊切除术的患者:结果:在排除了 11 名取消了鼓室切除术后 6 个月 CT 检查的患者后,仅对 39 名患者进行了分析。鼓室切除术后 6、12 和 24 个月的 NOB 发生率分别为 38.5%、55.2% 和 71.2%。手术肺的 NOB 发生率几乎是对侧非手术肺的 2 倍。男性、术前CT显示多发肺大泡、订书线过长(≥7厘米)、订书深度过深(≥1.5厘米)、切除样本较重(≥5克)被认为是NOB的危险因素:结论:我们发现 PSP 患者术后 NOB 的发生率很高。结论:我们发现 PSP 患者术后 NOB 的发生率很高。术后NOB的发生率很高,尤其是需要用长缝合线进行大体积肺切除的患者。
{"title":"Prospective Observation Study for Primary Spontaneous Pneumothorax: Incidence of and Risk Factors for Postoperative Neogenesis of Bullae.","authors":"Chihiro Furuta, Motoki Yano, Yuka Kitagawa, Ryotaro Katsuya, Naoki Ozeki, Takayuki Fukui","doi":"10.5761/atcs.oa.23-00206","DOIUrl":"10.5761/atcs.oa.23-00206","url":null,"abstract":"<p><strong>Purpose: </strong>Details of the neogenesis of bullae (NOB), which causes recurrent primary spontaneous pneumothorax (PSP) following bullectomy, have not been reported and risk factors for NOB remain unclear. We aimed to clarify the details of NOB.</p><p><strong>Methods: </strong>We conducted a prospective study using three computed tomography (CT) examinations performed 6, 12, and 24 months after bullectomy to identify the incidence of and risk factors for NOB. We enrolled 50 patients who underwent bullectomy for PSP.</p><p><strong>Results: </strong>After excluding 11 patients who canceled the postoperative CT examination at 6 months after bullectomy, only 39 patients were analyzed. The incidence of NOB at 6, 12, and 24 months after bullectomy was 38.5%, 55.2%, and 71.2%, respectively. The rate of NOB in the operated lung was almost 2 times higher than that in the contralateral nonoperative lung. Male sex, multiple bullae on preoperative CT, long stapling line (≥7 cm), deep stapling depth (≥1.5 cm), and heavier resected sample (≥5 g) were suggested to be risk factors for NOB.</p><p><strong>Conclusions: </strong>We recognized a high incidence of postoperative NOB in PSP patients. Bullectomy itself seems to promote NOB. Postoperative NOB occurs frequently, especially in patients who require a large-volume lung resection with a long staple line.</p>","PeriodicalId":93877,"journal":{"name":"Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11082493/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140861273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Posterior Papillary Muscle Suspension for Treating Systolic Anterior Motion in Hypertrophic Obstructive Cardiomyopathy. 治疗肥厚型梗阻性心肌病收缩期前移的乳头肌后悬吊术
Taiki Ito, Satoru Wakasa, Koji Sato, Shinji Abe, Taro Minamida

Systolic anterior motion of the anterior mitral leaflet can persist after ventricular septal myectomy for obstructive hypertrophic cardiomyopathy, resulting in residual pressure gradients and mitral regurgitation. However, additional procedures for systolic anterior motion involving mitral valve leaflet suturing and resection may lead to future valve disease. Therefore, we adopted posterior papillary muscle suspension, a subvalvular procedure for functional mitral regurgitation, to treat systolic anterior motion without directly intervening in the mitral valve leaflets. Papillary muscle suspension toward the posterior mitral annulus moved the papillary muscles away from the interventricular septum and successfully eliminated the systolic anterior motion and midventricular pressure gradient. In terms of avoiding direct mitral interventions, this procedure is a viable option for systolic anterior motion, especially in cases of very mild mitral regurgitation.

阻塞性肥厚型心肌病的室间隔缺损切除术后,二尖瓣前叶的收缩期前移可能会持续存在,导致残余压力梯度和二尖瓣反流。但是,如果为收缩期前移进行额外的二尖瓣瓣叶缝合和切除手术,可能会导致未来的瓣膜疾病。因此,我们采用了后方乳头肌悬吊术,这是一种治疗功能性二尖瓣反流的瓣下手术,可在不直接干预二尖瓣瓣叶的情况下治疗收缩期前移。乳头肌向二尖瓣环后方悬吊使乳头肌远离室间隔,成功消除了收缩期前移和室间隔中段压力梯度。就避免直接二尖瓣介入而言,该手术是治疗收缩期前移的可行方案,尤其是在二尖瓣反流非常轻微的病例中。
{"title":"Posterior Papillary Muscle Suspension for Treating Systolic Anterior Motion in Hypertrophic Obstructive Cardiomyopathy.","authors":"Taiki Ito, Satoru Wakasa, Koji Sato, Shinji Abe, Taro Minamida","doi":"10.5761/atcs.nm.23-00176","DOIUrl":"10.5761/atcs.nm.23-00176","url":null,"abstract":"<p><p>Systolic anterior motion of the anterior mitral leaflet can persist after ventricular septal myectomy for obstructive hypertrophic cardiomyopathy, resulting in residual pressure gradients and mitral regurgitation. However, additional procedures for systolic anterior motion involving mitral valve leaflet suturing and resection may lead to future valve disease. Therefore, we adopted posterior papillary muscle suspension, a subvalvular procedure for functional mitral regurgitation, to treat systolic anterior motion without directly intervening in the mitral valve leaflets. Papillary muscle suspension toward the posterior mitral annulus moved the papillary muscles away from the interventricular septum and successfully eliminated the systolic anterior motion and midventricular pressure gradient. In terms of avoiding direct mitral interventions, this procedure is a viable option for systolic anterior motion, especially in cases of very mild mitral regurgitation.</p>","PeriodicalId":93877,"journal":{"name":"Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10902854/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139725362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Excision of Giant Chronic Expanding Hematoma of the Thorax Caused by Rib Fractures after Proton Radiotherapy for Lung Cancer. 肺癌质子放疗后肋骨骨折引起的胸部巨大慢性膨胀性血肿切除术
Yukitaka Sato, Hironori Ishibashi, Yuki Funauchi, Kenichi Okubo

Chronic expanding hematoma (CEH) is defined as a hematoma that gradually expands over months to years. An 82-year-old female underwent proton radiotherapy for left upper lobe lung cancer 10 years previously. Two years after the therapy, a hematoma developed from the left 3rd to 5th dorsal rib fractures and gradually expanded, causing contraction of the left shoulder. Transcatheter arterial embolization was performed; however, the hematoma continued to expand with thrombocytopenia, and the platelet was decreased to 4.2 × 104/μL. Computed tomography showed a 17.2 × 14.0 × 10.0 cm mass between the left scapula and left dorsal ribs. The CEH of the thorax was completely excised with combined resection of the 3rd to 5th ribs, while the brachial plexus was preserved. Postoperatively, the platelet completely recovered and she could raise her left arm. A complete excision with surrounding organs preserved is the strategy used in the treatment of CEH of the thorax.

慢性膨胀性血肿(CEH)是指血肿在数月至数年内逐渐膨胀。一名 82 岁的女性在 10 年前因左上肺叶肺癌接受了质子放疗。治疗两年后,左侧第 3 至第 5 背肋骨骨折处出现血肿,并逐渐扩大,导致左肩挛缩。患者接受了经导管动脉栓塞治疗,但血肿继续扩大,血小板减少至 4.2 × 104/μL。计算机断层扫描显示,左侧肩胛骨和左侧背肋骨之间有一个 17.2 × 14.0 × 10.0 厘米的肿块。在联合切除第 3 至第 5 根肋骨的同时,完全切除了胸部的 CEH,并保留了臂丛神经。术后,血小板完全恢复,她可以抬起左臂。完全切除并保留周围器官是治疗胸部 CEH 的策略。
{"title":"Excision of Giant Chronic Expanding Hematoma of the Thorax Caused by Rib Fractures after Proton Radiotherapy for Lung Cancer.","authors":"Yukitaka Sato, Hironori Ishibashi, Yuki Funauchi, Kenichi Okubo","doi":"10.5761/atcs.cr.24.00121","DOIUrl":"10.5761/atcs.cr.24.00121","url":null,"abstract":"<p><p>Chronic expanding hematoma (CEH) is defined as a hematoma that gradually expands over months to years. An 82-year-old female underwent proton radiotherapy for left upper lobe lung cancer 10 years previously. Two years after the therapy, a hematoma developed from the left 3rd to 5th dorsal rib fractures and gradually expanded, causing contraction of the left shoulder. Transcatheter arterial embolization was performed; however, the hematoma continued to expand with thrombocytopenia, and the platelet was decreased to 4.2 × 10<sup>4</sup>/μL. Computed tomography showed a 17.2 × 14.0 × 10.0 cm mass between the left scapula and left dorsal ribs. The CEH of the thorax was completely excised with combined resection of the 3rd to 5th ribs, while the brachial plexus was preserved. Postoperatively, the platelet completely recovered and she could raise her left arm. A complete excision with surrounding organs preserved is the strategy used in the treatment of CEH of the thorax.</p>","PeriodicalId":93877,"journal":{"name":"Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11439597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142334221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extracorporeal Mechanical Circulatory Support after Pulmonary Thromboendarterectomy: Experience of One Center. 肺血栓内膜切除术后的体外机械循环支持:一家中心的经验。
Brunella Bertazzo, Alejandro Cicolini, Martin Fanilla, Liliana Favaloro, Jorge Caneva, Roberto R Favaloro

Purpose: Pulmonary thromboendarterectomy (PTE) is the treatment for patients with chronic thromboembolic disease. In the immediate postoperative period, some patients may still experience life-threatening complications such as reperfusion lung injury, airway bleeding, and persistent pulmonary hypertension with consequent right ventricular dysfunction. These issues may require support with extracorporeal membrane oxygenation (ECMO) as a bridge to recovery or lung transplantation. This study aims to analyze our series of PTEs that require ECMO.

Methods: A descriptive and retrospective analysis of all PTE performed at the Favaloro Foundation University Hospital was conducted between March 2013 and December 2023.

Results: A total of 42 patients underwent PTE with a median age of 47 years (interquartile range: 26-76). The incidence of patients with ECMO was 26.6%, of which 53.6% were veno-venous (VV) ECMO. Preoperatively, a low cardiac index (CI), high right and left filling pressures, and high total pulmonary vascular resistances (PVRs) were associated with ECMO with a statistically significant relationship. The hospital mortality was 11.9%, and the mortality in the ECMO group was 45.5%, with a statistically significant relationship. Veno-arterial ECMO has a worse prognosis than VV ECMO.

Conclusions: Preoperatively, a low CI, high right and left filling pressures, and high total PVRs were associated with ECMO after PTE.

目的:肺血栓内膜切除术(PTE)是治疗慢性血栓栓塞性疾病患者的方法。术后初期,一些患者仍可能出现危及生命的并发症,如再灌注肺损伤、气道出血、持续性肺动脉高压导致右心室功能障碍等。这些问题可能需要体外膜肺氧合(ECMO)的支持,作为康复或肺移植的桥梁。本研究旨在分析我们一系列需要 ECMO 的 PTE:方法:对 2013 年 3 月至 2023 年 12 月期间在法瓦罗罗基金会大学医院实施的所有 PTE 进行描述性和回顾性分析:共有 42 名患者接受了 PTE,中位年龄为 47 岁(四分位间范围:26-76 岁)。ECMO患者的发生率为26.6%,其中53.6%为静脉-静脉(VV)ECMO。术前,心脏指数(CI)低、左右充盈压高、总肺血管阻力(PVR)高与 ECMO 有显著的统计学关系。住院死亡率为 11.9%,而 ECMO 组的死亡率为 45.5%,两者之间有显著的统计学关系。静脉-动脉 ECMO 的预后比 VV ECMO 差:结论:术前,低 CI、高左右充盈压和高总 PVR 与 PTE 后 ECMO 相关。
{"title":"Extracorporeal Mechanical Circulatory Support after Pulmonary Thromboendarterectomy: Experience of One Center.","authors":"Brunella Bertazzo, Alejandro Cicolini, Martin Fanilla, Liliana Favaloro, Jorge Caneva, Roberto R Favaloro","doi":"10.5761/atcs.oa.24-00070","DOIUrl":"10.5761/atcs.oa.24-00070","url":null,"abstract":"<p><strong>Purpose: </strong>Pulmonary thromboendarterectomy (PTE) is the treatment for patients with chronic thromboembolic disease. In the immediate postoperative period, some patients may still experience life-threatening complications such as reperfusion lung injury, airway bleeding, and persistent pulmonary hypertension with consequent right ventricular dysfunction. These issues may require support with extracorporeal membrane oxygenation (ECMO) as a bridge to recovery or lung transplantation. This study aims to analyze our series of PTEs that require ECMO.</p><p><strong>Methods: </strong>A descriptive and retrospective analysis of all PTE performed at the Favaloro Foundation University Hospital was conducted between March 2013 and December 2023.</p><p><strong>Results: </strong>A total of 42 patients underwent PTE with a median age of 47 years (interquartile range: 26-76). The incidence of patients with ECMO was 26.6%, of which 53.6% were veno-venous (VV) ECMO. Preoperatively, a low cardiac index (CI), high right and left filling pressures, and high total pulmonary vascular resistances (PVRs) were associated with ECMO with a statistically significant relationship. The hospital mortality was 11.9%, and the mortality in the ECMO group was 45.5%, with a statistically significant relationship. Veno-arterial ECMO has a worse prognosis than VV ECMO.</p><p><strong>Conclusions: </strong>Preoperatively, a low CI, high right and left filling pressures, and high total PVRs were associated with ECMO after PTE.</p>","PeriodicalId":93877,"journal":{"name":"Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11320365/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141903912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the Factors Affecting Higher Hospitalization Cost of Lung Resection for Primary Lung Cancer: A Retrospective Cohort Study. 评估原发性肺癌肺切除术住院费用较高的影响因素:一项回顾性队列研究
Yukio Umeda, Shinsuke Matsumoto, Kiyohiko Hagiwara, Shoji Yoshikawa, Alex Chen

Purpose: This study aims to evaluate the factors associated with the higher hospitalization cost of lung resection for primary lung cancer to contribute to the reduction of healthcare spending.

Methods: A total of 435 consecutive primary lung cancer patients who underwent lung resection by a single surgeon at a single institution were enrolled. Baseline patient characteristics, operative procedures, postoperative complications, and postoperative courses were analyzed in relation to the hospitalization cost. Patients with higher costs (exceeding the third quartile [TQ]) were compared with patients with lower costs (less than TQ).

Results: Median and TQ medical costs for overall cases were 11177 US dollars (USD) and 12292 USD, respectively. Smoking history, history of coronary artery disease, previous thoracotomy, multiple sealant material use, transfusion, tumor factor T3 or higher, squamous cell carcinoma, postoperative complications, and longer postoperative hospital stay (>10 POD) were significant risk factors for increased hospitalization cost in multivariate analysis. The 5-year survival rate was significantly lower in the higher hospitalization cost group.

Conclusion: In addition to postoperative complications and prolonged hospitalization, patient background, histological types, and intraoperative factors were also considered as the risk factors for higher medical costs.

目的:本研究旨在评估原发性肺癌肺切除术住院费用较高的相关因素,为降低医疗支出做出贡献:研究共纳入了 435 名连续的原发性肺癌患者,这些患者均在一家医疗机构由一名外科医生进行了肺切除手术。分析了患者的基线特征、手术过程、术后并发症和术后疗程与住院费用的关系。将费用较高(超过第三四分位数[TQ])的患者与费用较低(低于第三四分位数)的患者进行比较:结果:所有病例的医疗费用中位数和四分位数分别为 11177 美元和 12292 美元。在多变量分析中,吸烟史、冠状动脉疾病史、既往胸廓切开术、多次使用密封材料、输血、肿瘤因子 T3 或更高、鳞状细胞癌、术后并发症和术后住院时间更长(>10 POD)是住院费用增加的重要风险因素。住院费用较高组的5年生存率明显较低:除了术后并发症和住院时间延长外,患者背景、组织学类型和术中因素也被认为是医疗费用增加的风险因素。
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引用次数: 0
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Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia
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