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Platinum-Based Adjuvant Chemotherapy for Stage II and Stage III Squamous Cell Carcinoma of the Lung. 铂基辅助化疗治疗II期和III期肺鳞状细胞癌。
T. Isaka, H. Nakayama, T. Yokose, H. Ito, K. Katayama, Kouzo Yamada, M. Masuda
INTRODUCTIONThe efficacy of platinum-based adjuvant chemotherapy (PBAC) for pathological stage II and stage III squamous cell carcinoma (SCC) of the lung was analyzed retrospectively.MATERIALS AND METHODSThe prognoses of 94 patients with stage II and stage III SCC with or without PBAC (more than three courses of cisplatin-, carboplatin-, and nedaplatin-based adjuvant chemotherapy) were compared.RESULTSThe mean observation period was 46.1 months. PBAC was not administered for the following reasons: 39 (55.7%) patients had comorbidities, 25 (35.7%) were older than 75 years, 19 (27.1%) patients underwent surgery before the approval of PBAC, and 3 (4.3%) patients could not continue PBAC (≤2 cycles) because of adverse events. PBAC patients (n = 24) were significantly younger than non-PBAC patients (n = 70; 66.3 vs 69.6 years old, respectively; p = 0.043). Disease-free survival (DFS) did not differ between PBAC and non-PBAC patients (55.0% and 67.1%, respectively; p = 0.266). PBAC patients tended to have worse overall survival (OS) than non-PBAC patients (56.1% and 70.2%, respectively; p = 0.138). PBAC was not prognostic for OS (hazard ratio (HR), 2.11; 95% confidence interval (CI), 0.82%-5.40%; p = 0.120).CONCLUSIONPBAC did not improve the prognoses of patients with pathological stage II or stage III SCC in the single institution experience.
回顾性分析铂基辅助化疗(PBAC)治疗病理II期和III期肺鳞癌(SCC)的疗效。材料和方法对94例II期和III期SCC患者的预后进行比较,这些患者有或没有PBAC(超过三个疗程的顺铂、卡铂和奈达铂辅助化疗)。结果平均观察期46.1个月。未给予PBAC的原因如下:39例(55.7%)患者有合并症,25例(35.7%)患者年龄大于75岁,19例(27.1%)患者在PBAC批准前接受过手术,3例(4.3%)患者因不良事件无法继续PBAC(≤2个周期)。PBAC患者(n = 24)明显比非PBAC患者(n = 70;分别为66.3岁和69.6岁;P = 0.043)。PBAC和非PBAC患者的无病生存率(DFS)无差异(分别为55.0%和67.1%;P = 0.266)。PBAC患者的总生存期(OS)往往比非PBAC患者差(分别为56.1%和70.2%;P = 0.138)。PBAC与OS无预后关系(风险比(HR), 2.11;95%置信区间(CI), 0.82% ~ 5.40%;P = 0.120)。结论:在单一机构的经验中,pbac并没有改善病理性II期或III期SCC患者的预后。
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引用次数: 9
Current Status and Future Prospects for Esophageal Cancer Treatment. 食管癌治疗的现状与展望
M. Sohda, H. Kuwano
The local control effect of esophagectomy with three-field lymph node dissection (3FLD) is reaching its limit pending technical advancement. Minimally invasive esophagectomy (MIE) by thoracotomy is slowly gaining acceptance due to advantages in short-term outcomes. Although the evidence is slowly increasing, MIE is still controversial. Also, the results of treatment by surgery alone are limiting, and multimodality therapy, which includes surgical and non-surgical treatment options including chemotherapy, radiotherapy, and endoscopic treatment, has become the mainstream therapy. Esophagectomy after neoadjuvant chemotherapy (NAC) is the standard treatment for clinical stages II/III (except for T4) esophageal cancer, whereas chemoradiotherapy (CRT) is regarded as the standard treatment for patients who wish to preserve their esophagus, those who refuse surgery, and those with inoperable disease. CRT is also usually selected for clinical stage IV esophageal cancer. On the other hand, with the spread of CRT, salvage esophagectomy has traditionally been recognized as a feasible option; however, many clinicians oppose the use of surgery due to the associated unfavorable morbidity and mortality profile. In the future, the improvement of each treatment result and the establishment of individual strategies are important although esophageal cancer has many treatment options.
由于技术的进步,食管切除术联合三野淋巴结清扫术(3FLD)的局部控制效果已经达到极限。开胸微创食管切除术(MIE)由于其短期疗效的优势而逐渐被人们所接受。尽管证据正在缓慢增加,但MIE仍然存在争议。此外,单纯手术治疗的效果有限,包括手术和非手术治疗方案,包括化疗、放疗、内镜治疗在内的多模式治疗已成为主流治疗方法。新辅助化疗后食管切除术(NAC)是临床II/III期(T4期除外)食管癌的标准治疗方法,而放化疗(CRT)则是希望保留食管、拒绝手术和无法手术的患者的标准治疗方法。临床IV期食管癌也常选择CRT。另一方面,随着CRT的普及,抢救性食管切除术传统上被认为是一种可行的选择;然而,由于相关的不利发病率和死亡率,许多临床医生反对使用手术。在未来,虽然食管癌有许多治疗选择,但提高每一种治疗效果和制定个体化治疗策略是很重要的。
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引用次数: 161
The Usefulness of Positron-Emission Tomography Findings in the Management of Anterior Mediastinal Tumors. 正电子发射断层扫描结果在前纵隔肿瘤治疗中的实用性。
Akihiko Kitami, Fumitoshi Sano, Shinichi Ohashi, Kosuke Suzuki, Shugo Uematsu, Takashi Suzuki, Mitsutaka Kadokura

Purpose: We performed a retrospective analysis to evaluate the usefulness of positron-emission tomography/computed tomography (PET/CT) findings in the classification and management of anterior mediastinal tumors.

Methods: Between 2006 and 2015, 105 patients with anterior mediastinal tumor received PET/CT. 18F-fluorodeoxyglucose (18F-FDG)-PET images were obtained 60 minutes after the injection of 18F-FDG.

Results: The histological classifications were as follows: thymoma (n = 49), thymic carcinoma (TC) (n = 19), malignant lymphoma (ML) (n = 8), teratoma (n = 7), thymic cyst (n = 14), and others (n = 8). Upon visual inspection (SUV max: >2.0), all of the malignant tumors showed 18F-FDG accumulation (with the exception of one type A thymoma). Two of the 14 thymic cysts and three of the seven teratomas showed slight 18F-FDG accumulation. The SUV max values of the low-grade thymomas, high-grade thymomas, TCs and MLs were 3.14 ± 0.73, 4.34 ± 1.49, 8.59 ± 3.05, and 10.08 ± 2.53, respectively, with significant differences between the low- and high-grade thymomas, and between TCs and MLs. The sensitivity, specificity and accuracy of 18F-FDG in the detection of low-grade thymomas and thymomas with a maximum diameter of ≤50 mm and an SUV max of ≤3.4 were 85%, 48%, and 60%, respectively.

Conclusion: FDG-PET/CT is an objective and useful modality in the differential diagnosis and management of anterior mediastinal tumors.

目的:我们进行了一项回顾性分析,评估正电子发射断层扫描/计算机断层扫描(PET/CT)结果在前纵隔肿瘤的分类和治疗中的作用:2006年至2015年间,105名前纵隔肿瘤患者接受了PET/CT检查。注射18F-脱氧葡萄糖(18F-FDG)60分钟后获得18F-FDG-PET图像:组织学分类如下:胸腺瘤(49 例)、胸腺癌(TC)(19 例)、恶性淋巴瘤(ML)(8 例)、畸胎瘤(7 例)、胸腺囊肿(14 例)和其他(8 例)。经肉眼观察(最大 SUV 值:>2.0),所有恶性肿瘤均显示有 18F-FDG 积累(一个 A 型胸腺瘤除外)。14 个胸腺囊肿中的 2 个和 7 个畸胎瘤中的 3 个有轻微的 18F-FDG 积聚。低级别胸腺瘤、高级别胸腺瘤、TC 和 ML 的 SUV max 值分别为(3.14±0.73)、(4.34±1.49)、(8.59±3.05)和(10.08±2.53),低级别和高级别胸腺瘤之间以及 TC 和 ML 之间差异显著。18F-FDG检测低级别胸腺瘤和最大直径≤50 mm、SUV max≤3.4的胸腺瘤的敏感性、特异性和准确性分别为85%、48%和60%:结论:FDG-PET/CT 是鉴别诊断和治疗前纵隔肿瘤的一种客观而有用的方法。
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引用次数: 0
Conduits Used in Coronary Artery Bypass Grafting: A Review of Morphological Studies. 冠状动脉旁路移植术中导管的形态学研究综述。
B. Martínez-González, C. G. Reyes-Hernández, A. Quiroga-Garza, Víctor E Rodríguez-Rodríguez, C. N. Esparza-Hernández, R. Elizondo-Omaña, S. Guzmán-López
There is a significant variety of vascular conduits options for coronary bypass surgery. Adequate graft selection is the most important factor for the success of the intervention. To ensure durability, permeability, and bypass function, there must be a morphological similarity between the graft and the coronary artery. The objective of this review was to analyze the morphological characteristics of the grafts that are most commonly used in coronary bypass surgery and the coronary arteries that are most frequently occluded. We included clinical information regarding the characteristics that determine the behavior of the grafts and its permeability over time. Currently, the internal thoracic artery is the standard choice for bypass surgery because of the morphological characteristics of the wall that makes less prone to developing atherosclerosis and hyperplasia. The radial and right gastroepiploic arteries are the following second and third best options, respectively. The ulnar artery is the preferred choice when other conduits are not feasible.
冠状动脉搭桥手术有多种血管导管可供选择。适当的移植物选择是干预成功的最重要因素。为了保证耐久性、渗透性和旁路功能,移植物和冠状动脉之间必须有形态上的相似性。本综述的目的是分析冠状动脉搭桥手术中最常用的移植物和最常闭塞的冠状动脉的形态学特征。我们纳入了有关决定移植物行为及其随时间渗透性的特征的临床信息。目前,胸内动脉是搭桥手术的标准选择,因为胸内动脉壁的形态学特征使其不易发生动脉粥样硬化和增生。桡动脉和右胃网膜动脉分别是第二和第三个最佳选择。当其他导管不可行时,尺动脉是首选。
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引用次数: 70
The Effects of Different BMI on Blood Loss and Transfusions in Chinese Patients Undergoing Coronary Artery Bypass Grafting. 不同BMI对中国冠状动脉搭桥术患者失血和输血的影响。
Mingya Wang, Ming Chen, Hushan Ao, Sipeng Chen, Zhifa Wang
OBJECTIVEBlood loss is a predictor of outcomes after coronary artery bypass grafting (CABG). This study investigated the effects of body mass index (BMI) on blood loss, blood transfusion rate, and the variations in coagulation parameters of Chinese patients undergoing CABG.METHODSA total of 1007 Chinese patients who consecutively underwent isolated, primary CABG at Fuwai Hospital from January 1, 2013 to December 31, 2013 were included in this study. They were categorized by BMI into <24 kg/m2 (low and normal weight group), 24≤ BMI <28 kg/m2 (overweight group), and BMI ≥28 kg/m2 (obese group). Following this BMI classification, the quantities of blood lost and recorded transfusions were analyzed.RESULTSBlood loss and transfusion rates were significantly higher in the low and normal weight group compared with the obese group (p <0.01). Chest tube drainage over 24 h, duration of intensive care unit (ICU) stay, and postoperative mechanical ventilation were higher as well (p <0.01). Atrial fibrillation was closely related to blood transfusion (p <0.001).CONCLUSIONSObesity is a predictor for protection against blood loss and transfusion in Chinese people. Patients with low and normal BMI lost more blood per kg of their weight and had higher total transfused volume during isolated primary CABG. Atrial fibrillation was associated with high blood transfusion.
目的:失血是冠状动脉旁路移植术(CABG)后预后的预测指标。本研究探讨体重指数(BMI)对中国冠状动脉搭桥患者出血量、输血率及凝血参数变化的影响。方法选取2013年1月1日至2013年12月31日在阜外医院连续行孤立原发性冠脉搭桥的1007例中国患者作为研究对象。按BMI分为BMI <24 kg/m2组(低、正常体重组)、24≤BMI <28 kg/m2组(超重组)、BMI≥28 kg/m2组(肥胖组)。根据BMI分类,分析失血量和记录的输血量。结果低体重组和正常体重组的失血量和输血率明显高于肥胖组(p <0.01)。24 h胸管引流、重症监护病房(ICU)住院时间、术后机械通气时间均高于对照组(p <0.01)。心房颤动与输血密切相关(p <0.001)。结论肥胖是中国人预防失血和输血的一个预测指标。在孤立的原发性冠脉搭桥期间,BMI较低和正常的患者每公斤体重失血量更多,总输血量也更高。心房颤动与大量输血有关。
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引用次数: 27
Deep Sternal Wound Infection after Open-Heart Surgery: A 13-Year Single Institution Analysis. 心内直视手术后深胸骨伤口感染:13年单一机构分析。
A. A. Juhl, Sofie Hody, T. S. Videbaek, T. Damsgaard, P. Nielsen
PURPOSEThe present study aimed to compare the clinical outcome for patients with or without muscle flap reconstruction after deep sternal wound infection due to open-heart surgery.METHODSThe study was a retrospective cohort study, including patients who developed deep sternal wound infection after open-heart surgery in the Western Denmark Region from 1999 to 2011. Journals of included patients were reviewed for clinical data regarding the treatment of their sternal defect. Patients were divided into two groups depending on whether they received a muscle-flap-based sternal reconstruction or traditional rewiring of the sternum.RESULTSA total of 130 patients developed deep sternal wound infection in the study period. In all, 12 patients died before being discharged, leaving a total of 118 patients for analysis. Of these, 50 (42%) patients received muscle flap reconstruction. Muscle flap recipients had significantly longer total hospital stays (p <0.001). However, after receiving muscle flap reconstruction, patients were discharged after a median of 14 days, with 74% not needing additional surgery.CONCLUSIONIt is difficult to predict which patients eventually require muscle flap reconstruction after deep sternal wound infection. Although patients receiving muscle flap reconstructions have longer hospital stays, they are quickly discharged after the reconstruction.
目的比较心内直视手术后胸骨深部伤口感染行或不行肌肉瓣重建的临床效果。方法本研究为回顾性队列研究,纳入1999 - 2011年西丹麦地区心内直视手术后发生胸骨深部伤口感染的患者。纳入的患者的期刊回顾临床资料有关治疗他们的胸骨缺损。病人被分为两组,这取决于他们是否接受了基于肌肉瓣的胸骨重建或传统的胸骨重新布线。结果研究期间共有130例患者发生胸骨深部伤口感染。总共有12名患者在出院前死亡,总共有118名患者需要分析。其中,50例(42%)患者接受了肌瓣重建。肌肉瓣接受者的总住院时间明显延长(p <0.001)。然而,接受肌肉瓣重建后,患者平均14天后出院,74%的患者不需要额外的手术。结论胸骨深创面感染后哪些患者最终需要肌皮瓣重建难以预测。虽然接受肌瓣重建的患者住院时间较长,但重建后很快出院。
{"title":"Deep Sternal Wound Infection after Open-Heart Surgery: A 13-Year Single Institution Analysis.","authors":"A. A. Juhl, Sofie Hody, T. S. Videbaek, T. Damsgaard, P. Nielsen","doi":"10.5761/atcs.oa.16-00196","DOIUrl":"https://doi.org/10.5761/atcs.oa.16-00196","url":null,"abstract":"PURPOSE\u0000The present study aimed to compare the clinical outcome for patients with or without muscle flap reconstruction after deep sternal wound infection due to open-heart surgery.\u0000\u0000\u0000METHODS\u0000The study was a retrospective cohort study, including patients who developed deep sternal wound infection after open-heart surgery in the Western Denmark Region from 1999 to 2011. Journals of included patients were reviewed for clinical data regarding the treatment of their sternal defect. Patients were divided into two groups depending on whether they received a muscle-flap-based sternal reconstruction or traditional rewiring of the sternum.\u0000\u0000\u0000RESULTS\u0000A total of 130 patients developed deep sternal wound infection in the study period. In all, 12 patients died before being discharged, leaving a total of 118 patients for analysis. Of these, 50 (42%) patients received muscle flap reconstruction. Muscle flap recipients had significantly longer total hospital stays (p <0.001). However, after receiving muscle flap reconstruction, patients were discharged after a median of 14 days, with 74% not needing additional surgery.\u0000\u0000\u0000CONCLUSION\u0000It is difficult to predict which patients eventually require muscle flap reconstruction after deep sternal wound infection. Although patients receiving muscle flap reconstructions have longer hospital stays, they are quickly discharged after the reconstruction.","PeriodicalId":93877,"journal":{"name":"Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86241778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
Efficacy of the Stonehenge Technique for Minimally Invasive Aortic Valve Replacement via Right Infraaxillary Thoracotomy. 巨石阵技术在右腋下开胸微创主动脉瓣置换术中的疗效观察。
M. Yamazaki, H. Kin, Shohei Kitamoto, Shota Yamanaka, H. Nishida, K. Nishigawa, S. Takanashi
Minimally invasive cardiac surgeries for aortic valve replacement (AVR) are still a technical challenge for surgeons because these procedures are undertaken through small incisions and deep surgical fields. Although AVR via vertical infraaxillary thoracotomy can be a cosmetically superior option, a disadvantage of this approach is the distance between the thoracotomy incision and the ascending aorta. Therefore, we devised a technique to perform all manipulations using the fingertips without the aid of a knot pusher or long-shafted surgical instruments. This was achieved by particular placement of several retracted sutures to the right chest wall. We named placement of these sutures the "Stonehenge technique." In conclusion, AVR via vertical infraaxillary thoracotomy with our Stonehenge technique can be safely and simply performed with superior cosmetic advantages.
对于外科医生来说,微创心脏主动脉瓣置换术(AVR)仍然是一个技术挑战,因为这些手术是通过小切口和深手术野进行的。虽然经垂直腋下开胸行AVR在美容上是一种优越的选择,但这种方法的缺点是开胸切口与升主动脉之间的距离。因此,我们设计了一种技术来执行所有操作的指尖没有帮助的结推或长轴手术器械。这是通过在右胸壁上放置几条缩回缝合线来实现的。我们将这些缝合线的放置命名为“巨石阵技术”。综上所述,我们的巨石阵技术经腋下垂直开胸AVR可以安全、简单地进行,具有优越的美容优势。
{"title":"Efficacy of the Stonehenge Technique for Minimally Invasive Aortic Valve Replacement via Right Infraaxillary Thoracotomy.","authors":"M. Yamazaki, H. Kin, Shohei Kitamoto, Shota Yamanaka, H. Nishida, K. Nishigawa, S. Takanashi","doi":"10.5761/atcs.nm.16-00248","DOIUrl":"https://doi.org/10.5761/atcs.nm.16-00248","url":null,"abstract":"Minimally invasive cardiac surgeries for aortic valve replacement (AVR) are still a technical challenge for surgeons because these procedures are undertaken through small incisions and deep surgical fields. Although AVR via vertical infraaxillary thoracotomy can be a cosmetically superior option, a disadvantage of this approach is the distance between the thoracotomy incision and the ascending aorta. Therefore, we devised a technique to perform all manipulations using the fingertips without the aid of a knot pusher or long-shafted surgical instruments. This was achieved by particular placement of several retracted sutures to the right chest wall. We named placement of these sutures the \"Stonehenge technique.\" In conclusion, AVR via vertical infraaxillary thoracotomy with our Stonehenge technique can be safely and simply performed with superior cosmetic advantages.","PeriodicalId":93877,"journal":{"name":"Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78360665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Giant Leiomyoma Arising from the Mediastinal Pleura: A Case Report. 源自纵隔胸膜的巨大平滑肌瘤1例。
N. Haratake, F. Shoji, Yuka Kozuma, T. Okamoto, Y. Maehara
This report presents a rare case involving a patient with a giant leiomyoma originating from the mediastinal pleura. The patient underwent a medical examination, and chest radiography revealed a giant tumor. Computed tomography (CT) and magnetic resonance imaging (MRI) showed a well demarcated, heterogeneous mass which seemed to originate from the posterior mediastinum. Positron emission tomography (PET) showed the uptake of this tumor with a standardized uptake value of 4.9. We suspected that this tumor was a solitary fibrous tumor, and the patient underwent a surgical resection. Intraoperative exploration revealed a well-encapsulated tumor measuring 15 × 11 cm that appeared to originate from the mediastinal pleura. Immunohistochemical findings revealed a benign leiomyoma. We finally diagnosed the patient with a mediastinal leiomyoma. The present report describes CT, MRI, and PET findings of leiomyoma, and presents a review of relevant literature.
本文报告一个罕见的病例,涉及一个巨大的平滑肌瘤起源于纵隔胸膜。病人接受了医学检查,胸部x光片显示有一个巨大的肿瘤。计算机断层扫描(CT)和磁共振成像(MRI)显示一个界限清楚的非均匀肿块,似乎起源于后纵隔。正电子发射断层扫描(PET)显示该肿瘤的摄取,标准摄取值为4.9。我们怀疑这个肿瘤是一个孤立的纤维性肿瘤,病人接受了手术切除。术中探查发现一个包膜良好的肿瘤,大小为15 × 11 cm,似乎起源于纵隔胸膜。免疫组化结果显示为良性平滑肌瘤。我们最终诊断患者为纵隔平滑肌瘤。本报告描述了平滑肌瘤的CT, MRI和PET的表现,并提出了相关文献的回顾。
{"title":"Giant Leiomyoma Arising from the Mediastinal Pleura: A Case Report.","authors":"N. Haratake, F. Shoji, Yuka Kozuma, T. Okamoto, Y. Maehara","doi":"10.5761/atcs.cr.16-00137","DOIUrl":"https://doi.org/10.5761/atcs.cr.16-00137","url":null,"abstract":"This report presents a rare case involving a patient with a giant leiomyoma originating from the mediastinal pleura. The patient underwent a medical examination, and chest radiography revealed a giant tumor. Computed tomography (CT) and magnetic resonance imaging (MRI) showed a well demarcated, heterogeneous mass which seemed to originate from the posterior mediastinum. Positron emission tomography (PET) showed the uptake of this tumor with a standardized uptake value of 4.9. We suspected that this tumor was a solitary fibrous tumor, and the patient underwent a surgical resection. Intraoperative exploration revealed a well-encapsulated tumor measuring 15 × 11 cm that appeared to originate from the mediastinal pleura. Immunohistochemical findings revealed a benign leiomyoma. We finally diagnosed the patient with a mediastinal leiomyoma. The present report describes CT, MRI, and PET findings of leiomyoma, and presents a review of relevant literature.","PeriodicalId":93877,"journal":{"name":"Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89868784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Clinical Evaluation and Outcomes of Digital Chest Drainage after Lung Resection. 肺切除术后指胸引流的临床评价及效果。
F. Shoji, S. Takamori, T. Akamine, G. Toyokawa, Y. Morodomi, T. Okamoto, Y. Maehara
BACKGROUNDAnalog chest drainage systems (ACS) are generally used to monitor postoperative alveolar air leakage (PAL) after lung resection. An electronic digital chest drainage system (DCS) has recently been developed that reportedly has several advantages over the traditional ACS. Here, we report a single institution's experience of PAL management with the DCS. We also sought to establish whether DCS had superior clinical benefits and outcomes compared with ACS.METHODSWe enrolled 112 consecutive patients who underwent lung resection and were subsequently managed with DCS. We compared PAL rate, duration of chest drainage, and the incidence of complications with a group of 121 consecutive patients previously managed with ACS after lung resection, using propensity score matching.RESULTSMean maximum and minimum PAL rates during DCS chest drainage were 48.9 ml/min (range: 2.0-868.6 ml/min) and 0.1 ml/min (0.0-1.2 ml/min), respectively. Mean PAL rate at DCS removal was 1.3 ml/min (0.0-10.0 ml/min). After propensity score matching, mean duration of chest drainage was significantly shorter with DCS than ACS (2.7 days, range: 1-9 days, compared with 3.7 days, range: 1-21 days, respectively; P = 0.031).CONCLUSIONSManaging PAL with DCS after pulmonary resection appears to reduce the duration of chest drainage.
模拟胸腔引流系统(ACS)通常用于监测肺切除术后肺泡漏气(PAL)。电子数字胸腔引流系统(DCS)最近被开发出来,据报道它比传统的ACS有几个优点。在这里,我们报告一个机构的经验,PAL管理与DCS。我们还试图确定DCS与ACS相比是否具有更好的临床益处和结果。方法:我们招募了112例连续接受肺切除术并随后进行DCS治疗的患者。我们使用倾向评分匹配法比较了121例连续肺切除术后ACS患者的PAL率、胸腔引流时间和并发症发生率。结果DCS胸腔引流术中PAL平均最大值48.9 ml/min(范围:2.0 ~ 868.6 ml/min),最小值0.1 ml/min(范围:0.0 ~ 1.2 ml/min)。DCS去除的PAL平均速率为1.3 ml/min (0.0-10.0 ml/min)。倾向评分匹配后,DCS组胸腔引流的平均持续时间明显短于ACS组(分别为2.7天,范围1-9天,3.7天,范围1-21天);P = 0.031)。结论肺切除术后用DCS处理PAL可缩短胸腔引流时间。
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引用次数: 14
Does Surgical Repair Still have a Role for Iatrogenic Tracheobronchial Rupture? Clinical Analysis of a Thoracic Surgeon's Opinion. 手术修复对医源性气管支气管破裂仍有作用吗?一位胸外科医生意见的临床分析。
S. Lee, Do Hyung Kim, Sang Kwon Lee, Y. Kim, J. Cho, H. I
PURPOSEThe choice of surgical repair or conservative treatment for iatrogenic tracheobronchial rupture (ITBR) remains controversial. However, thoracic surgeons consider that surgical repair is an important treatment modality. The purpose of this study was to evaluate the clinical results from the perspective of the surgery-preferred group.METHODSWe treated 11 patients (8 women and 3 men; age: 52.6 ± 22.9 years) with ITBR from January 2011 to January 2016. A posterolateral thoracotomy or a trans-tracheal approach was performed according to the mechanism of injury.RESULTSNine patients underwent surgery, and all patients received primary repair. Five patients received a right posterolateral thoracotomy, whereas one patient received a left posterolateral thoracotomy. No mortality or morbidity related to the surgery was observed. The mechanical ventilation time was 65.9 ± 99.2 hours. The intensive care unit duration was 19.7 ± 33.3 days. Two patients received conservative treatment, and all patients died of another disease that was not related to the conservative treatment.CONCLUSIONOur mortality or morbidity due to surgery was not higher than world literature results of conservative treatment. We thought surgery is the primary treatment choice for ITBR in the absence of a good indication for conservative treatment.
目的医源性气管支气管破裂(ITBR)是手术修复还是保守治疗一直存在争议。然而,胸外科医生认为手术修复是一种重要的治疗方式。本研究的目的是从手术偏好组的角度评估临床结果。方法11例患者(女8例,男3例;年龄:52.6±22.9岁(2011年1月- 2016年1月)。根据损伤机制,采用后外侧开胸或经气管入路。结果9例患者行手术治疗,所有患者均接受了初步修复。5例患者接受右后外侧开胸术,1例患者接受左后外侧开胸术。没有观察到与手术相关的死亡率或发病率。机械通气时间为65.9±99.2 h。重症监护时间19.7±33.3 d。2例患者接受保守治疗,所有患者均死于与保守治疗无关的其他疾病。结论本组手术死亡率和发病率均不高于世界文献保守治疗的结果。我们认为手术是ITBR的主要治疗选择在保守治疗缺乏良好的指征。
{"title":"Does Surgical Repair Still have a Role for Iatrogenic Tracheobronchial Rupture? Clinical Analysis of a Thoracic Surgeon's Opinion.","authors":"S. Lee, Do Hyung Kim, Sang Kwon Lee, Y. Kim, J. Cho, H. I","doi":"10.5761/atcs.oa.16-00189","DOIUrl":"https://doi.org/10.5761/atcs.oa.16-00189","url":null,"abstract":"PURPOSE\u0000The choice of surgical repair or conservative treatment for iatrogenic tracheobronchial rupture (ITBR) remains controversial. However, thoracic surgeons consider that surgical repair is an important treatment modality. The purpose of this study was to evaluate the clinical results from the perspective of the surgery-preferred group.\u0000\u0000\u0000METHODS\u0000We treated 11 patients (8 women and 3 men; age: 52.6 ± 22.9 years) with ITBR from January 2011 to January 2016. A posterolateral thoracotomy or a trans-tracheal approach was performed according to the mechanism of injury.\u0000\u0000\u0000RESULTS\u0000Nine patients underwent surgery, and all patients received primary repair. Five patients received a right posterolateral thoracotomy, whereas one patient received a left posterolateral thoracotomy. No mortality or morbidity related to the surgery was observed. The mechanical ventilation time was 65.9 ± 99.2 hours. The intensive care unit duration was 19.7 ± 33.3 days. Two patients received conservative treatment, and all patients died of another disease that was not related to the conservative treatment.\u0000\u0000\u0000CONCLUSION\u0000Our mortality or morbidity due to surgery was not higher than world literature results of conservative treatment. We thought surgery is the primary treatment choice for ITBR in the absence of a good indication for conservative treatment.","PeriodicalId":93877,"journal":{"name":"Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83032300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
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Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia
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