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The Effects of Different BMI on Blood Loss and Transfusions in Chinese Patients Undergoing Coronary Artery Bypass Grafting. 不同BMI对中国冠状动脉搭桥术患者失血和输血的影响。
Mingya Wang, Ming Chen, Hushan Ao, Sipeng Chen, Zhifa Wang
OBJECTIVEBlood loss is a predictor of outcomes after coronary artery bypass grafting (CABG). This study investigated the effects of body mass index (BMI) on blood loss, blood transfusion rate, and the variations in coagulation parameters of Chinese patients undergoing CABG.METHODSA total of 1007 Chinese patients who consecutively underwent isolated, primary CABG at Fuwai Hospital from January 1, 2013 to December 31, 2013 were included in this study. They were categorized by BMI into <24 kg/m2 (low and normal weight group), 24≤ BMI <28 kg/m2 (overweight group), and BMI ≥28 kg/m2 (obese group). Following this BMI classification, the quantities of blood lost and recorded transfusions were analyzed.RESULTSBlood loss and transfusion rates were significantly higher in the low and normal weight group compared with the obese group (p <0.01). Chest tube drainage over 24 h, duration of intensive care unit (ICU) stay, and postoperative mechanical ventilation were higher as well (p <0.01). Atrial fibrillation was closely related to blood transfusion (p <0.001).CONCLUSIONSObesity is a predictor for protection against blood loss and transfusion in Chinese people. Patients with low and normal BMI lost more blood per kg of their weight and had higher total transfused volume during isolated primary CABG. Atrial fibrillation was associated with high blood transfusion.
目的:失血是冠状动脉旁路移植术(CABG)后预后的预测指标。本研究探讨体重指数(BMI)对中国冠状动脉搭桥患者出血量、输血率及凝血参数变化的影响。方法选取2013年1月1日至2013年12月31日在阜外医院连续行孤立原发性冠脉搭桥的1007例中国患者作为研究对象。按BMI分为BMI <24 kg/m2组(低、正常体重组)、24≤BMI <28 kg/m2组(超重组)、BMI≥28 kg/m2组(肥胖组)。根据BMI分类,分析失血量和记录的输血量。结果低体重组和正常体重组的失血量和输血率明显高于肥胖组(p <0.01)。24 h胸管引流、重症监护病房(ICU)住院时间、术后机械通气时间均高于对照组(p <0.01)。心房颤动与输血密切相关(p <0.001)。结论肥胖是中国人预防失血和输血的一个预测指标。在孤立的原发性冠脉搭桥期间,BMI较低和正常的患者每公斤体重失血量更多,总输血量也更高。心房颤动与大量输血有关。
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引用次数: 27
Deep Sternal Wound Infection after Open-Heart Surgery: A 13-Year Single Institution Analysis. 心内直视手术后深胸骨伤口感染:13年单一机构分析。
A. A. Juhl, Sofie Hody, T. S. Videbaek, T. Damsgaard, P. Nielsen
PURPOSEThe present study aimed to compare the clinical outcome for patients with or without muscle flap reconstruction after deep sternal wound infection due to open-heart surgery.METHODSThe study was a retrospective cohort study, including patients who developed deep sternal wound infection after open-heart surgery in the Western Denmark Region from 1999 to 2011. Journals of included patients were reviewed for clinical data regarding the treatment of their sternal defect. Patients were divided into two groups depending on whether they received a muscle-flap-based sternal reconstruction or traditional rewiring of the sternum.RESULTSA total of 130 patients developed deep sternal wound infection in the study period. In all, 12 patients died before being discharged, leaving a total of 118 patients for analysis. Of these, 50 (42%) patients received muscle flap reconstruction. Muscle flap recipients had significantly longer total hospital stays (p <0.001). However, after receiving muscle flap reconstruction, patients were discharged after a median of 14 days, with 74% not needing additional surgery.CONCLUSIONIt is difficult to predict which patients eventually require muscle flap reconstruction after deep sternal wound infection. Although patients receiving muscle flap reconstructions have longer hospital stays, they are quickly discharged after the reconstruction.
目的比较心内直视手术后胸骨深部伤口感染行或不行肌肉瓣重建的临床效果。方法本研究为回顾性队列研究,纳入1999 - 2011年西丹麦地区心内直视手术后发生胸骨深部伤口感染的患者。纳入的患者的期刊回顾临床资料有关治疗他们的胸骨缺损。病人被分为两组,这取决于他们是否接受了基于肌肉瓣的胸骨重建或传统的胸骨重新布线。结果研究期间共有130例患者发生胸骨深部伤口感染。总共有12名患者在出院前死亡,总共有118名患者需要分析。其中,50例(42%)患者接受了肌瓣重建。肌肉瓣接受者的总住院时间明显延长(p <0.001)。然而,接受肌肉瓣重建后,患者平均14天后出院,74%的患者不需要额外的手术。结论胸骨深创面感染后哪些患者最终需要肌皮瓣重建难以预测。虽然接受肌瓣重建的患者住院时间较长,但重建后很快出院。
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引用次数: 21
Efficacy of the Stonehenge Technique for Minimally Invasive Aortic Valve Replacement via Right Infraaxillary Thoracotomy. 巨石阵技术在右腋下开胸微创主动脉瓣置换术中的疗效观察。
M. Yamazaki, H. Kin, Shohei Kitamoto, Shota Yamanaka, H. Nishida, K. Nishigawa, S. Takanashi
Minimally invasive cardiac surgeries for aortic valve replacement (AVR) are still a technical challenge for surgeons because these procedures are undertaken through small incisions and deep surgical fields. Although AVR via vertical infraaxillary thoracotomy can be a cosmetically superior option, a disadvantage of this approach is the distance between the thoracotomy incision and the ascending aorta. Therefore, we devised a technique to perform all manipulations using the fingertips without the aid of a knot pusher or long-shafted surgical instruments. This was achieved by particular placement of several retracted sutures to the right chest wall. We named placement of these sutures the "Stonehenge technique." In conclusion, AVR via vertical infraaxillary thoracotomy with our Stonehenge technique can be safely and simply performed with superior cosmetic advantages.
对于外科医生来说,微创心脏主动脉瓣置换术(AVR)仍然是一个技术挑战,因为这些手术是通过小切口和深手术野进行的。虽然经垂直腋下开胸行AVR在美容上是一种优越的选择,但这种方法的缺点是开胸切口与升主动脉之间的距离。因此,我们设计了一种技术来执行所有操作的指尖没有帮助的结推或长轴手术器械。这是通过在右胸壁上放置几条缩回缝合线来实现的。我们将这些缝合线的放置命名为“巨石阵技术”。综上所述,我们的巨石阵技术经腋下垂直开胸AVR可以安全、简单地进行,具有优越的美容优势。
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引用次数: 7
Giant Leiomyoma Arising from the Mediastinal Pleura: A Case Report. 源自纵隔胸膜的巨大平滑肌瘤1例。
N. Haratake, F. Shoji, Yuka Kozuma, T. Okamoto, Y. Maehara
This report presents a rare case involving a patient with a giant leiomyoma originating from the mediastinal pleura. The patient underwent a medical examination, and chest radiography revealed a giant tumor. Computed tomography (CT) and magnetic resonance imaging (MRI) showed a well demarcated, heterogeneous mass which seemed to originate from the posterior mediastinum. Positron emission tomography (PET) showed the uptake of this tumor with a standardized uptake value of 4.9. We suspected that this tumor was a solitary fibrous tumor, and the patient underwent a surgical resection. Intraoperative exploration revealed a well-encapsulated tumor measuring 15 × 11 cm that appeared to originate from the mediastinal pleura. Immunohistochemical findings revealed a benign leiomyoma. We finally diagnosed the patient with a mediastinal leiomyoma. The present report describes CT, MRI, and PET findings of leiomyoma, and presents a review of relevant literature.
本文报告一个罕见的病例,涉及一个巨大的平滑肌瘤起源于纵隔胸膜。病人接受了医学检查,胸部x光片显示有一个巨大的肿瘤。计算机断层扫描(CT)和磁共振成像(MRI)显示一个界限清楚的非均匀肿块,似乎起源于后纵隔。正电子发射断层扫描(PET)显示该肿瘤的摄取,标准摄取值为4.9。我们怀疑这个肿瘤是一个孤立的纤维性肿瘤,病人接受了手术切除。术中探查发现一个包膜良好的肿瘤,大小为15 × 11 cm,似乎起源于纵隔胸膜。免疫组化结果显示为良性平滑肌瘤。我们最终诊断患者为纵隔平滑肌瘤。本报告描述了平滑肌瘤的CT, MRI和PET的表现,并提出了相关文献的回顾。
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引用次数: 14
Clinical Evaluation and Outcomes of Digital Chest Drainage after Lung Resection. 肺切除术后指胸引流的临床评价及效果。
F. Shoji, S. Takamori, T. Akamine, G. Toyokawa, Y. Morodomi, T. Okamoto, Y. Maehara
BACKGROUNDAnalog chest drainage systems (ACS) are generally used to monitor postoperative alveolar air leakage (PAL) after lung resection. An electronic digital chest drainage system (DCS) has recently been developed that reportedly has several advantages over the traditional ACS. Here, we report a single institution's experience of PAL management with the DCS. We also sought to establish whether DCS had superior clinical benefits and outcomes compared with ACS.METHODSWe enrolled 112 consecutive patients who underwent lung resection and were subsequently managed with DCS. We compared PAL rate, duration of chest drainage, and the incidence of complications with a group of 121 consecutive patients previously managed with ACS after lung resection, using propensity score matching.RESULTSMean maximum and minimum PAL rates during DCS chest drainage were 48.9 ml/min (range: 2.0-868.6 ml/min) and 0.1 ml/min (0.0-1.2 ml/min), respectively. Mean PAL rate at DCS removal was 1.3 ml/min (0.0-10.0 ml/min). After propensity score matching, mean duration of chest drainage was significantly shorter with DCS than ACS (2.7 days, range: 1-9 days, compared with 3.7 days, range: 1-21 days, respectively; P = 0.031).CONCLUSIONSManaging PAL with DCS after pulmonary resection appears to reduce the duration of chest drainage.
模拟胸腔引流系统(ACS)通常用于监测肺切除术后肺泡漏气(PAL)。电子数字胸腔引流系统(DCS)最近被开发出来,据报道它比传统的ACS有几个优点。在这里,我们报告一个机构的经验,PAL管理与DCS。我们还试图确定DCS与ACS相比是否具有更好的临床益处和结果。方法:我们招募了112例连续接受肺切除术并随后进行DCS治疗的患者。我们使用倾向评分匹配法比较了121例连续肺切除术后ACS患者的PAL率、胸腔引流时间和并发症发生率。结果DCS胸腔引流术中PAL平均最大值48.9 ml/min(范围:2.0 ~ 868.6 ml/min),最小值0.1 ml/min(范围:0.0 ~ 1.2 ml/min)。DCS去除的PAL平均速率为1.3 ml/min (0.0-10.0 ml/min)。倾向评分匹配后,DCS组胸腔引流的平均持续时间明显短于ACS组(分别为2.7天,范围1-9天,3.7天,范围1-21天);P = 0.031)。结论肺切除术后用DCS处理PAL可缩短胸腔引流时间。
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引用次数: 14
Does Surgical Repair Still have a Role for Iatrogenic Tracheobronchial Rupture? Clinical Analysis of a Thoracic Surgeon's Opinion. 手术修复对医源性气管支气管破裂仍有作用吗?一位胸外科医生意见的临床分析。
S. Lee, Do Hyung Kim, Sang Kwon Lee, Y. Kim, J. Cho, H. I
PURPOSEThe choice of surgical repair or conservative treatment for iatrogenic tracheobronchial rupture (ITBR) remains controversial. However, thoracic surgeons consider that surgical repair is an important treatment modality. The purpose of this study was to evaluate the clinical results from the perspective of the surgery-preferred group.METHODSWe treated 11 patients (8 women and 3 men; age: 52.6 ± 22.9 years) with ITBR from January 2011 to January 2016. A posterolateral thoracotomy or a trans-tracheal approach was performed according to the mechanism of injury.RESULTSNine patients underwent surgery, and all patients received primary repair. Five patients received a right posterolateral thoracotomy, whereas one patient received a left posterolateral thoracotomy. No mortality or morbidity related to the surgery was observed. The mechanical ventilation time was 65.9 ± 99.2 hours. The intensive care unit duration was 19.7 ± 33.3 days. Two patients received conservative treatment, and all patients died of another disease that was not related to the conservative treatment.CONCLUSIONOur mortality or morbidity due to surgery was not higher than world literature results of conservative treatment. We thought surgery is the primary treatment choice for ITBR in the absence of a good indication for conservative treatment.
目的医源性气管支气管破裂(ITBR)是手术修复还是保守治疗一直存在争议。然而,胸外科医生认为手术修复是一种重要的治疗方式。本研究的目的是从手术偏好组的角度评估临床结果。方法11例患者(女8例,男3例;年龄:52.6±22.9岁(2011年1月- 2016年1月)。根据损伤机制,采用后外侧开胸或经气管入路。结果9例患者行手术治疗,所有患者均接受了初步修复。5例患者接受右后外侧开胸术,1例患者接受左后外侧开胸术。没有观察到与手术相关的死亡率或发病率。机械通气时间为65.9±99.2 h。重症监护时间19.7±33.3 d。2例患者接受保守治疗,所有患者均死于与保守治疗无关的其他疾病。结论本组手术死亡率和发病率均不高于世界文献保守治疗的结果。我们认为手术是ITBR的主要治疗选择在保守治疗缺乏良好的指征。
{"title":"Does Surgical Repair Still have a Role for Iatrogenic Tracheobronchial Rupture? Clinical Analysis of a Thoracic Surgeon's Opinion.","authors":"S. Lee, Do Hyung Kim, Sang Kwon Lee, Y. Kim, J. Cho, H. I","doi":"10.5761/atcs.oa.16-00189","DOIUrl":"https://doi.org/10.5761/atcs.oa.16-00189","url":null,"abstract":"PURPOSE\u0000The choice of surgical repair or conservative treatment for iatrogenic tracheobronchial rupture (ITBR) remains controversial. However, thoracic surgeons consider that surgical repair is an important treatment modality. The purpose of this study was to evaluate the clinical results from the perspective of the surgery-preferred group.\u0000\u0000\u0000METHODS\u0000We treated 11 patients (8 women and 3 men; age: 52.6 ± 22.9 years) with ITBR from January 2011 to January 2016. A posterolateral thoracotomy or a trans-tracheal approach was performed according to the mechanism of injury.\u0000\u0000\u0000RESULTS\u0000Nine patients underwent surgery, and all patients received primary repair. Five patients received a right posterolateral thoracotomy, whereas one patient received a left posterolateral thoracotomy. No mortality or morbidity related to the surgery was observed. The mechanical ventilation time was 65.9 ± 99.2 hours. The intensive care unit duration was 19.7 ± 33.3 days. Two patients received conservative treatment, and all patients died of another disease that was not related to the conservative treatment.\u0000\u0000\u0000CONCLUSION\u0000Our mortality or morbidity due to surgery was not higher than world literature results of conservative treatment. We thought surgery is the primary treatment choice for ITBR in the absence of a good indication for conservative treatment.","PeriodicalId":93877,"journal":{"name":"Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83032300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
Cystic Adventitial Disease of the Common Femoral Artery. Case Report and Review of the Literature. 股总动脉囊性外膜病。病例报告及文献回顾。
Hideaki Maeda, Tomofumi Umeda, Hideomi Kawachi, A. Iida, Yusuke Ishii, Michinari Kono, M. Shiono
PURPOSECystic adventitial artery disease is an uncommon non-atherosclerotic peripheral vessel disease. Furthermore cystic adventitial disease of the common femoral artery is an extremely rare entity. We report the case of a 54 year-old man complaining of intermittent claudication who was referred to our vascular service.METHODS AND RESULTSDoppler ultrasound and multidetector-row computed tomography (CT) with 3-dimensional volume rendering revealed severe stenosis with cystic an adventitial cyst in the common femoral artery. Intra-operative Doppler ultrasound showed the cyst to be multilocular type. Reversed great saphenous vein interposition was successfully placed.CONCLUSIONRemoval of cyst together with artery and interposition using reversed great saphenous vein is the optimal treatment procedure to prevent recurrence.
目的:囊性外动脉疾病是一种少见的非动脉粥样硬化性外周血管疾病。此外,股总动脉囊性外膜疾病是一种极为罕见的疾病。我们报告的情况下,一个54岁的男子抱怨间歇性跛行谁是指我们的血管服务。方法与结果多普勒超声和三维容积显像的多排计算机断层扫描(CT)显示股总动脉严重狭窄并伴有囊性和外膜囊肿。术中多普勒超声显示囊肿为多房型。大隐静脉逆行间置成功。结论囊肿切除联合大隐静脉介入术是预防复发的最佳治疗方法。
{"title":"Cystic Adventitial Disease of the Common Femoral Artery. Case Report and Review of the Literature.","authors":"Hideaki Maeda, Tomofumi Umeda, Hideomi Kawachi, A. Iida, Yusuke Ishii, Michinari Kono, M. Shiono","doi":"10.5761/ATCS.CR.15-00269","DOIUrl":"https://doi.org/10.5761/ATCS.CR.15-00269","url":null,"abstract":"PURPOSE\u0000Cystic adventitial artery disease is an uncommon non-atherosclerotic peripheral vessel disease. Furthermore cystic adventitial disease of the common femoral artery is an extremely rare entity. We report the case of a 54 year-old man complaining of intermittent claudication who was referred to our vascular service.\u0000\u0000\u0000METHODS AND RESULTS\u0000Doppler ultrasound and multidetector-row computed tomography (CT) with 3-dimensional volume rendering revealed severe stenosis with cystic an adventitial cyst in the common femoral artery. Intra-operative Doppler ultrasound showed the cyst to be multilocular type. Reversed great saphenous vein interposition was successfully placed.\u0000\u0000\u0000CONCLUSION\u0000Removal of cyst together with artery and interposition using reversed great saphenous vein is the optimal treatment procedure to prevent recurrence.","PeriodicalId":93877,"journal":{"name":"Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85207928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Mid-Term Outcomes of a Modification of Extended Aortic Arch Anastomosis with Pulmonary Artery Banding in Single Ventricle Neonates with Hypoplastic Transverse Arch. 延长主动脉弓吻合术加肺动脉束带治疗横弓发育不全单心室新生儿中期疗效观察。
Bui Quoc Thang, T. Furugaki, M. Osaka, Yutaka Watanabe, S. Kanemoto, F. Suetsugu, Y. Hiramatsu
PURPOSEThere is less certainty regarding the best strategy for treating neonates with functional single ventricle (SV) and hypoplastic aortic arch. We have applied a modified extended aortic arch anastomosis (EAAA) and main pulmonary artery banding (PAB) as an initial palliation in neonates with transverse arch hypoplasia and assessed the mid-term outcomes.METHODSIn total, 10 neonates with functional SV and extensive hypoplasia or interruption of the arch underwent a modified EAAA (extended arch anastomosis with a subclavian flap) concomitant with main PAB through a thoracotomy without cardiopulmonary bypass. Patient age and weight ranged from 4 to 14 days and 2.3 to 3.8 kg, respectively.RESULTSThere were no hospital deaths although there were two late deaths. Gradients across the arch were 0 to 7 mmHg at postoperative day 1 and no arch reoperations were required. Two patients required balloon aortoplasty. Nine underwent bidirectional cavopulmonary shunt and two of them needed concomitant Damus-Kaye-Stansel (DKS) anastomosis. Six have completed Fontan.CONCLUSIONOur modification of EAAA with main PAB for SV neonates may benefit a certain population with transverse arch hypoplasia as an option to be considered. Patients with the potential for developing outflow obstruction may be best managed with an initial DKS-type palliation.
目的:关于新生儿功能性单心室(SV)和主动脉弓发育不全的最佳治疗策略尚不确定。我们应用改良的扩展主动脉弓吻合术(EAAA)和肺动脉主动脉绑扎术(PAB)作为横弓发育不全新生儿的初始缓解,并评估中期结果。方法对10例功能性SV伴广泛弓发育不全或弓中断的新生儿行改良EAAA(锁骨下皮瓣扩展弓吻合)合并主PAB经开胸,不经体外循环。患者年龄为4 ~ 14天,体重为2.3 ~ 3.8 kg。结果无院内死亡,有2例晚期死亡。术后第1天,整个弓的梯度为0 ~ 7 mmHg,无需再进行弓部手术。2例患者需要气囊主动脉成形术。9例行双向腔隙肺分流术,2例行DKS吻合。六家已经完成了丰坦。结论我们对SV新生儿的EAAA进行以PAB为主的改良,可能会使一定的横弓发育不全人群受益。可能发展为流出道梗阻的患者最好采用初始dks型姑息治疗。
{"title":"Mid-Term Outcomes of a Modification of Extended Aortic Arch Anastomosis with Pulmonary Artery Banding in Single Ventricle Neonates with Hypoplastic Transverse Arch.","authors":"Bui Quoc Thang, T. Furugaki, M. Osaka, Yutaka Watanabe, S. Kanemoto, F. Suetsugu, Y. Hiramatsu","doi":"10.5761/atcs.oa.16-00170","DOIUrl":"https://doi.org/10.5761/atcs.oa.16-00170","url":null,"abstract":"PURPOSE\u0000There is less certainty regarding the best strategy for treating neonates with functional single ventricle (SV) and hypoplastic aortic arch. We have applied a modified extended aortic arch anastomosis (EAAA) and main pulmonary artery banding (PAB) as an initial palliation in neonates with transverse arch hypoplasia and assessed the mid-term outcomes.\u0000\u0000\u0000METHODS\u0000In total, 10 neonates with functional SV and extensive hypoplasia or interruption of the arch underwent a modified EAAA (extended arch anastomosis with a subclavian flap) concomitant with main PAB through a thoracotomy without cardiopulmonary bypass. Patient age and weight ranged from 4 to 14 days and 2.3 to 3.8 kg, respectively.\u0000\u0000\u0000RESULTS\u0000There were no hospital deaths although there were two late deaths. Gradients across the arch were 0 to 7 mmHg at postoperative day 1 and no arch reoperations were required. Two patients required balloon aortoplasty. Nine underwent bidirectional cavopulmonary shunt and two of them needed concomitant Damus-Kaye-Stansel (DKS) anastomosis. Six have completed Fontan.\u0000\u0000\u0000CONCLUSION\u0000Our modification of EAAA with main PAB for SV neonates may benefit a certain population with transverse arch hypoplasia as an option to be considered. Patients with the potential for developing outflow obstruction may be best managed with an initial DKS-type palliation.","PeriodicalId":93877,"journal":{"name":"Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84153029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-Term Outcomes of Conventional Aortic Valve Replacement in High-Risk Patients: Where Do We Stand? 高危患者常规主动脉瓣置换术的长期疗效:我们站在哪里?
F. Nicolini, D. Fortuna, G. A. Contini, D. Pacini, D. Gabbieri, R. De Palma, T. Gherli
PURPOSEThe introduction of transcatheter aortic valves has focused attention on the results of conventional aortic valve surgery in high-risk patients. The aim of the study was to evaluate 5-years outcomes in this category of patients in the current surgical era.METHODSThis is an observational retrospective study of 581 high-risk patients undergoing aortic valve replacement from 2008 to 2013, with a mean logistic EuroSCORE of 26.6% ± 14.6%. Data were prospectively collected in a database of Emilia-Romagna region (Italy).RESULTSOverall 30-day mortality was 9.3%. Stroke rate was 1.5%. At 1-, 3-, and 5-years overall mortality was 18.2%, 30.4%, and 42.2%, cardiac death rate was 3.9%, 9.2%, and 12.9%, stroke rate 2.5%, 7.7%, and 10.2%, re-operation occurrence 0.2%, 0.9% and 1.3%, and new pacemaker implantation was 2.3%, 5.1% and 7.8%. At multivariate analysis, urgency, hemodynamic instability, LVEF ≤30%, NYHA III-IV, severe chronic obstructive pulmonary disease (COPD), extra-cardiac arteriopathy, cerebrovascular disease, and creatinine >2.0 mg/dL remained independent predictors of 5-year mortality.CONCLUSIONThe results of the current study add weight to the evidence that traditional aortic valve replacement can be performed in high-risk patients with satisfactory 5-year mortality and morbidity. Our study may help to improve decision-making in this category of high-risk patients with aortic valve disease.
目的:经导管主动脉瓣的引入引起了人们对高危患者常规主动脉瓣手术效果的关注。本研究的目的是评估这类患者在当前手术时代的5年预后。方法对2008 - 2013年581例接受主动脉瓣置换术的高危患者进行观察性回顾性研究,平均logistic EuroSCORE为26.6%±14.6%。数据在意大利艾米利亚-罗马涅地区的数据库中进行前瞻性收集。结果30天总死亡率为9.3%。卒中发生率为1.5%。1年、3年和5年总死亡率分别为18.2%、30.4%和42.2%,心脏死亡率分别为3.9%、9.2%和12.9%,卒中发生率分别为2.5%、7.7%和10.2%,再手术发生率分别为0.2%、0.9%和1.3%,新起搏器植入率分别为2.3%、5.1%和7.8%。在多因素分析中,急症、血流动力学不稳定、LVEF≤30%、NYHA III-IV、严重慢性阻塞性肺疾病(COPD)、心外动脉病变、脑血管疾病和肌酐>2.0 mg/dL仍然是5年死亡率的独立预测因素。结论本研究结果进一步证明,传统的主动脉瓣置换术对高危患者具有满意的5年死亡率和发病率。我们的研究可能有助于改善这类高危主动脉瓣疾病患者的决策。
{"title":"Long-Term Outcomes of Conventional Aortic Valve Replacement in High-Risk Patients: Where Do We Stand?","authors":"F. Nicolini, D. Fortuna, G. A. Contini, D. Pacini, D. Gabbieri, R. De Palma, T. Gherli","doi":"10.5761/ATCS.OA.16-00165","DOIUrl":"https://doi.org/10.5761/ATCS.OA.16-00165","url":null,"abstract":"PURPOSE\u0000The introduction of transcatheter aortic valves has focused attention on the results of conventional aortic valve surgery in high-risk patients. The aim of the study was to evaluate 5-years outcomes in this category of patients in the current surgical era.\u0000\u0000\u0000METHODS\u0000This is an observational retrospective study of 581 high-risk patients undergoing aortic valve replacement from 2008 to 2013, with a mean logistic EuroSCORE of 26.6% ± 14.6%. Data were prospectively collected in a database of Emilia-Romagna region (Italy).\u0000\u0000\u0000RESULTS\u0000Overall 30-day mortality was 9.3%. Stroke rate was 1.5%. At 1-, 3-, and 5-years overall mortality was 18.2%, 30.4%, and 42.2%, cardiac death rate was 3.9%, 9.2%, and 12.9%, stroke rate 2.5%, 7.7%, and 10.2%, re-operation occurrence 0.2%, 0.9% and 1.3%, and new pacemaker implantation was 2.3%, 5.1% and 7.8%. At multivariate analysis, urgency, hemodynamic instability, LVEF ≤30%, NYHA III-IV, severe chronic obstructive pulmonary disease (COPD), extra-cardiac arteriopathy, cerebrovascular disease, and creatinine >2.0 mg/dL remained independent predictors of 5-year mortality.\u0000\u0000\u0000CONCLUSION\u0000The results of the current study add weight to the evidence that traditional aortic valve replacement can be performed in high-risk patients with satisfactory 5-year mortality and morbidity. Our study may help to improve decision-making in this category of high-risk patients with aortic valve disease.","PeriodicalId":93877,"journal":{"name":"Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82303718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Effect of the Nuss Procedure on the Physical Development of Patients with Pectus Excavatum. Nuss手术对漏斗胸患者身体发育的影响。
H. Kim, J. Y. Yoon, Kook Nam Han, Y. Choi
PURPOSEThis study assessed physical development of patients with pectus excavatum and evaluated the effect of the Nuss procedure on physical development.METHODSA total of 146 patients underwent the Nuss procedure; of these, at the time of the study, the bar had been removed from 123 patients (84.9%; male 93, female 30) who were eligible for participation in this study. Heights and body weights of patients were measured prior to surgery and immediately before bar removal. Chest computed tomography (CT) was performed preoperatively and immediately before bar removal. The associations between physical development and chest CT indices were evaluated.RESULTSThe height standard deviation score (SDS) was - 0.66 ± 2.23 preoperatively and 0.04 ± 1.34 immediately before bar removal (p <0.01). The weight SDS was - 0.02 ± 2.59 preoperatively; it increased significantly to 0.56 ± 1.56 immediately before bar removal (p <0.01). The Haller index (3.85 ± 1.18 to 2.99 ± 0.54; p <0.01) and asymmetric index (9.75 ± 6.63 to 7.01 ± 4.77; p <0.01) also showed improvements.CONCLUSIONSThe Nuss procedure may contribute positively to the physical development of patients with pectus excavatum.
目的评估漏斗胸患者的身体发育,评价Nuss手术对其身体发育的影响。方法对146例患者行Nuss手术;其中,在研究开始时,123例患者(84.9%;男性93人,女性30人,均符合参加本研究的条件。在手术前和取棒前测量患者的身高和体重。术前及取棒前均行胸部CT检查。评估体格发育与胸部CT指标之间的关系。结果术前高度标准差(SDS)为- 0.66±2.23,拔除前高度标准差(SDS)为0.04±1.34 (p <0.01)。术前体重SDS为- 0.02±2.59;拔除棒材前立即升高至0.56±1.56 (p <0.01)。哈勒指数(3.85±1.18 ~ 2.99±0.54);P <0.01),非对称指数(9.75±6.63 ~ 7.01±4.77);P <0.01)也有改善。结论Nuss手术对漏斗胸患者的身体发育有积极的促进作用。
{"title":"Effect of the Nuss Procedure on the Physical Development of Patients with Pectus Excavatum.","authors":"H. Kim, J. Y. Yoon, Kook Nam Han, Y. Choi","doi":"10.5761/atcs.oa.16-00012","DOIUrl":"https://doi.org/10.5761/atcs.oa.16-00012","url":null,"abstract":"PURPOSE\u0000This study assessed physical development of patients with pectus excavatum and evaluated the effect of the Nuss procedure on physical development.\u0000\u0000\u0000METHODS\u0000A total of 146 patients underwent the Nuss procedure; of these, at the time of the study, the bar had been removed from 123 patients (84.9%; male 93, female 30) who were eligible for participation in this study. Heights and body weights of patients were measured prior to surgery and immediately before bar removal. Chest computed tomography (CT) was performed preoperatively and immediately before bar removal. The associations between physical development and chest CT indices were evaluated.\u0000\u0000\u0000RESULTS\u0000The height standard deviation score (SDS) was - 0.66 ± 2.23 preoperatively and 0.04 ± 1.34 immediately before bar removal (p <0.01). The weight SDS was - 0.02 ± 2.59 preoperatively; it increased significantly to 0.56 ± 1.56 immediately before bar removal (p <0.01). The Haller index (3.85 ± 1.18 to 2.99 ± 0.54; p <0.01) and asymmetric index (9.75 ± 6.63 to 7.01 ± 4.77; p <0.01) also showed improvements.\u0000\u0000\u0000CONCLUSIONS\u0000The Nuss procedure may contribute positively to the physical development of patients with pectus excavatum.","PeriodicalId":93877,"journal":{"name":"Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90788712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
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Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia
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