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Clinical Characteristics of Ear Chondroid Syringoma: A Report of 2 Cases and a Literature Review. 耳软骨瘤的临床特征:两例病例报告和文献综述。
Pub Date : 2025-01-13 DOI: 10.1177/01455613241310585
Wenwen Qi, Shuai Xu, Yazhou Zhang, Shuaijun Zhang, Changle Li, Haiyuan Zhu, Jie Han, Ming Xia, Fengyang Xie

Chondroid syringoma, a mixed tumor of the skin, is an acquired hamartoma that differentiates into hair follicles, sebaceous glands, and apocrine sweat glands. Chondroid syringoma in the ear region is exceptionally rare. However, we present 2 cases of ear chondroid syringoma: 1 involving multiple lesions in the external auditory canal and the other including a single lesion behind the auricle. We reviewed relevant literature to offer insights into the diagnosis and treatment of ear tumors in the future.

软骨样注射器瘤是一种混合性皮肤肿瘤,是一种后天错构瘤,可分化为毛囊、皮脂腺和大汗腺。在耳朵区域的软骨样淋巴瘤是非常罕见的。然而,我们报告了2例耳部软骨样鼓膜瘤:1例涉及外耳道的多个病变,另1例包括耳廓后的单个病变。我们回顾了相关文献,以期对耳部肿瘤的诊断和治疗提供一些见解。
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引用次数: 0
Exploring the Intricate Connection Between Vitamin B12 Deficiency and Hearing Loss: A Systematic Literature Review. 探索维生素B12缺乏和听力损失之间的复杂联系:系统的文献综述。
Pub Date : 2025-01-11 DOI: 10.1177/01455613241298070
Joyline Rodrigues, Shubhangi Anand, Dhanshree R Gunjawate, Kaushlendra Kumar, Rohit Ravi

Background: Vitamin B12 is an essential nutrient crucial for overall health, and deficiencies can lead to hearing loss. Objective: The aim of the systematic review was to explore the intricate connection between vitamin B12 deficiency and hearing loss using a systematic literature review. Methods: A systematic literature search was carried out to identify the articles exploring the connection between vitamin B12 deficiency and hearing loss. Electronic databases such as PubMed, Scopus, and Cochrane databases were used to identify the relevant studies. Results: A total of 612 studies were identified from 3 databases, and after stepwise screening, 9 articles were found eligible for the data extraction and inclusion in the review. Most of the studies had observed statistically-significant differences in the hearing thresholds with low vitamin B12 levels. However, few studies found hearing loss in the low frequencies (250 and 500 Hz), and others have found elevated thresholds above 4 KHz. Factors such as age, gender, and treatment for vitamin B12 did not show any significant changes in the hearing thresholds. Conclusion: The systematic review revealed that individuals with lower vitamin B12 levels tended to have a higher prevalence of hearing impairment than those with normal or elevated levels. Vitamin B12 deficiency, coupled with high homocysteine levels and low folate concentrations, may contribute to different degrees of hearing loss, particularly in the elderly. Lower serum levels of vitamin B12 have been associated with slight to mild hearing loss, while cochlear dysfunction and poorer hearing thresholds have also been observed in individuals with vitamin B12 deficiency. These findings highlight the importance of maintaining optimal levels of vitamin B12 for preserving hearing health and warrant further investigation into potential interventions.

背景:维生素B12是一种对整体健康至关重要的必需营养素,缺乏维生素B12会导致听力损失。目的:本系统综述的目的是通过系统的文献综述来探讨维生素B12缺乏与听力损失之间的复杂联系。方法:通过系统的文献检索,找出探讨维生素B12缺乏与听力损失之间关系的文章。使用PubMed、Scopus和Cochrane等电子数据库确定相关研究。结果:从3个数据库中共筛选到612篇研究,经逐步筛选,有9篇文章符合数据提取纳入综述。大多数研究都观察到低维生素B12水平的听力阈值有统计学上的显著差异。然而,很少有研究发现低频率(250和500赫兹)的听力损失,而其他研究发现4千赫以上的阈值升高。年龄、性别和维生素B12治疗等因素在听力阈值方面没有显示出任何显著变化。结论:系统评价显示,维生素B12水平较低的个体比正常或较高水平的个体更容易出现听力障碍。维生素B12缺乏,加上高同型半胱氨酸水平和低叶酸浓度,可能导致不同程度的听力损失,尤其是老年人。血清中维生素B12水平较低与轻度至轻度听力损失有关,而缺乏维生素B12的人也会出现耳蜗功能障碍和听力阈值较低的情况。这些发现强调了维持最佳水平的维生素B12对保持听力健康的重要性,并值得进一步研究潜在的干预措施。
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引用次数: 0
Crohn's Disease Manifestation as An Intranasal Space-Occupying Lesion. 克罗恩病表现为鼻内占位性病变。
Pub Date : 2025-01-08 DOI: 10.1177/01455613241310581
Tamara Zaseeva, Shany Havazelet, Igor Vainer, Ella Matmon, Dror Shouval, Gal Avishai, Roy Hod, Dror Gilony
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引用次数: 0
Global Burden of Otitis Media Attributable to Secondhand Smoke in 204 Countries and Territories from 1990 to 2019: The Analysis of the Global Burden of Disease Study. 1990年至2019年204个国家和地区因二手烟导致的全球中耳炎负担:全球疾病负担研究分析
Pub Date : 2025-01-07 DOI: 10.1177/01455613241310582
Shuhan Liu, Sirui Wang, Xiaofeng Fan, Wei Tang, Yongran Cheng, Yu Sun, Wendi Shi, Lili Dai

Objective: Secondhand smoke (SHS) is a major public health concern. In this study, we evaluated the global burden of otitis media (OM) due to SHS exposure during 1990-2019 and explored the impact of socioeconomic factors on it.

Methods: With reference to the 2019 Global Burden of Disease (GBD) data, we assessed the OM burden linked to SHS during 1990-2019, stratified by gender, GBD region, and country. Join-point regression models analyzed trends in OM burden by calculating the average annual percent change (AAPC). Spearman's correlation examined the relationship between the Socio-demographic Index (SDI), Healthcare Access and Quality (HAQ) index, and SHS-related OM burden.

Results: During 1990-2019, age-standardized disability-adjusted life years (ASDRs) and age-standardized mortality rates (ASMRs) for OM due to SHS declined globally, with AAPCs of -1.45 for ASDR and -7.97 for ASMR. Significant declines in ASMR were noted in low-to-middle SDI regions. Regionally, Eastern Sub-Saharan Africa had the highest OM-related deaths, while South Asia had the highest disability-adjusted life years. OM burden decreased with higher SDI and HAQ.

Conclusion: Despite global declines, significant regional and national disparities remained, which emphasizes the need for targeted interventions.

目的:二手烟(SHS)是一个主要的公共卫生问题。在本研究中,我们评估了1990-2019年间SHS暴露导致的全球中耳炎(OM)负担,并探讨了社会经济因素对其的影响。方法:参考2019年全球疾病负担(GBD)数据,按性别、GBD地区和国家进行分层,评估1990-2019年与SHS相关的OM负担。结合点回归模型通过计算年均百分比变化(AAPC)来分析OM负担的趋势。Spearman相关检验了社会人口统计指数(SDI)、医疗保健可及性和质量(HAQ)指数与shs相关OM负担之间的关系。结果:在1990-2019年期间,全球范围内SHS引起的OM的年龄标准化残疾调整生命年(ASDRs)和年龄标准化死亡率(ASMRs)下降,ASDR的aapc为-1.45,ASMR为-7.97。低至中等SDI地区的ASMR显著下降。从区域来看,撒哈拉以南非洲东部的om相关死亡人数最高,而南亚的残疾调整生命年数最高。随着SDI和HAQ的增加,OM负担降低。结论:尽管全球下降,但显著的区域和国家差异仍然存在,这强调了有针对性干预措施的必要性。
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引用次数: 0
Radiofrequency Coblation Inferior Turbinoplasty with Modified UPPP for the Treatment of Obstructive Sleep Apnea-Hypopnea Syndrome. 改良UPPP射频消融下鼻甲成形术治疗阻塞性睡眠呼吸暂停低通气综合征。
Pub Date : 2025-01-01 DOI: 10.1177/01455613241307525
Qiushi Tian, Teng Chu, Mingjie Pang

Objective: To compare the efficacy of surgical treatment in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) involving a standalone modified uvulopalatopharyngoplasty (mUPPP) and radiofrequency coblation inferior turbinoplasty with mUPPP. Methods: In this study, a retrospective analysis of 79 OSAHS patients with inferior turbinate hypertrophy and oropharyngeal obstruction undergoing surgical treatment was performed. According to the different surgical methods, the patients were divided into 2 groups (Group A and Group B). Group A included 36 patients treated with standalone mUPPP. Group B included 43 patients treated with mUPPP and bilateral radiofrequency coblation inferior turbinoplasty. Polysomnography (PSG), active anterior rhinomanometry, surgical success rate, and surgical complication were used to assess the patients in 2 groups. The successful surgical result was defined as a 50% or greater decrease in the apnea-hypopnea index (AHI) in postoperative PSG. Results: Before surgery, there were no significant differences in age, gender, neck circumference, body mass index, Friedman tongue position grade, tonsil size grade, Epworth sleepiness scale score, total inferior turbinate size grade, total nasal resistance (TNR), AHI and the lowest O2 saturation (LSaO2) between the 2 groups. After 6 months of follow-up visits, AHI, LSaO2, and TNR in Group B showed a significant improvement compared to Group A. The surgical success rate was 76.74% in Group B compared to 52.78% in Group A (P = .025). There was no significant difference in the total surgical complication rate between the 2 groups (13.89% vs 23.26%, P = .290). Conclusion: For OSAHS patients with inferior turbinate hypertrophy and oropharyngeal obstruction, radiofrequency coblation inferior turbinoplasty with mUPPP appears to be a more effective surgical method than mUPPP alone.

目的:比较独立改良悬垂腭咽成形术(mUPPP)与射频消融下鼻甲成形术治疗阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的疗效。方法:回顾性分析79例手术治疗的OSAHS下鼻甲肥大合并口咽梗阻患者的临床资料。根据手术方式的不同,将患者分为A组和B组。A组36例患者采用独立mUPPP治疗。B组43例患者行mUPPP和双侧射频消融下鼻甲成形术。采用多导睡眠图(PSG)、主动前鼻测压、手术成功率、手术并发症等指标对两组患者进行评估。手术成功的定义是术后PSG的呼吸暂停低通气指数(AHI)下降50%或以上。结果:术前,两组患者在年龄、性别、颈围、体重指数、Friedman舌位分级、扁桃体大小分级、Epworth嗜睡评分、总下鼻甲大小分级、总鼻阻力(TNR)、AHI、最低血氧饱和度(LSaO2)等方面比较,差异均无统计学意义。随访6个月后,B组AHI、LSaO2、TNR均较a组有明显改善,手术成功率为76.74%,a组为52.78% (P = 0.025)。两组手术总并发症发生率比较,差异无统计学意义(13.89% vs 23.26%, P = 0.290)。结论:对于伴有下鼻甲肥大和口咽梗阻的OSAHS患者,射频消融下鼻甲成形术联合mUPPP比单纯使用mUPPP更有效。
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引用次数: 0
The Development of the Mastoid Drill. 乳突钻的发展。
Pub Date : 2025-01-01 DOI: 10.1177/01455613241311252
Kais Jawawdeh, Glenn Isaacson
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引用次数: 0
Cavernous Hemangioma of the External Auditory Canal Involving the Tympanic Membrane: Case Report and Literature Review. 外耳道海绵状血管瘤累及鼓膜:1例报告及文献复习。
Pub Date : 2025-01-01 DOI: 10.1177/01455613241312072
Qingli Huang, Haiping Qin, Lianqing Li, Lili Gong, Yanhui Lv

Cavernous hemangiomas of the external auditory canal simultaneously affecting the tympanic membrane are extremely rare. Endoscopic otosurgery has been successfully used for resecting various ear lesions because of its wider surgical field of view and minimal trauma. We report the case of a 50-year-old male patient who presented with a 6-month history of left ear congestion. Otoendoscopic examination of the left ear revealed a dark red neoplasm blocking the bony external auditory canal. After admission, surgical contraindications were eliminated, and the patient underwent otoendoscopic resection of the canal tumor. Postoperatively, the patient's symptoms were relieved, and there was no reoccurrence during the 1-month follow-up. The tumor was successfully removed using otoendoscopy, followed by tympanoplasty.

外耳道海绵状血管瘤同时影响鼓膜是极为罕见的。内窥镜耳外科手术因其手术视野开阔,创伤小,已成功用于各种耳部病变的切除。我们报告的情况下,50岁的男性患者谁提出了6个月的历史左耳充血。左耳内窥镜检查发现一个暗红色的肿瘤阻塞了骨性外耳道。入院后,手术禁忌症消除,患者行耳内镜肿瘤切除术。术后患者症状缓解,随访1个月无复发。使用耳内窥镜成功切除肿瘤,随后进行鼓室成形术。
{"title":"Cavernous Hemangioma of the External Auditory Canal Involving the Tympanic Membrane: Case Report and Literature Review.","authors":"Qingli Huang, Haiping Qin, Lianqing Li, Lili Gong, Yanhui Lv","doi":"10.1177/01455613241312072","DOIUrl":"https://doi.org/10.1177/01455613241312072","url":null,"abstract":"<p><p>Cavernous hemangiomas of the external auditory canal simultaneously affecting the tympanic membrane are extremely rare. Endoscopic otosurgery has been successfully used for resecting various ear lesions because of its wider surgical field of view and minimal trauma. We report the case of a 50-year-old male patient who presented with a 6-month history of left ear congestion. Otoendoscopic examination of the left ear revealed a dark red neoplasm blocking the bony external auditory canal. After admission, surgical contraindications were eliminated, and the patient underwent otoendoscopic resection of the canal tumor. Postoperatively, the patient's symptoms were relieved, and there was no reoccurrence during the 1-month follow-up. The tumor was successfully removed using otoendoscopy, followed by tympanoplasty.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613241312072"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Unique Case of Metastatic Oral Kaposi Sarcoma in an HIV-Negative Patient. 艾滋病毒阴性患者转移性口腔卡波西肉瘤的独特病例
Pub Date : 2025-01-01 DOI: 10.1177/01455613241307536
Spencer H Short, Michael McGlone, Chetan S Nayak

Kaposi's sarcoma (KS) is a tumor involving blood vessels and lymphatic tissue. It is caused by human herpes virus-8, typically in HIV infection in individuals with AIDS. There are 4 major types of KS including classic, endemic, immunosuppression, and AIDS-related. Endemic KS is unique among the different types as it is associated with patients with HIV-seronegative and can present either as an indolent tumor or as a fast-growing mass. The authors discuss a unique presentation of metastatic, endemic KS in a patient with HIV-negative, non-immunosuppression, which has yet to be described in the United States. A 38-year-old male with a history of same-sex partners, presented with a new oral lesion that had appeared 6 weeks ago. He was negative for human papillomavirus or HIV infection. A computed tomography (CT) scan demonstrated destructive lesions of the hard palate. The specimens obtained from biopsy were consistent with endemic KS. A Positron Emission Tomography - computed tomography (PET-CT) scan showed widely-metastatic disease. Case reports have described a rare subtype of HIV-seronegative KS in men who have sex with men. However, these are typically-indolent tumors with exclusively-cutaneous manifestation. This is a unique case of aggressive, widely-metastatic endemic KS metastatic in a patient with HIV-negative.

卡波西肉瘤(KS)是一种累及血管和淋巴组织的肿瘤。它是由人类疱疹病毒-8引起的,通常在艾滋病患者中感染艾滋病毒。KS主要有四种类型,包括经典的、地方性的、免疫抑制的和艾滋病相关的。地方性KS在不同类型中是独特的,因为它与hiv血清阴性患者相关,可以表现为惰性肿瘤或快速生长的肿块。作者讨论了一种独特的转移性,地方性KS患者的hiv阴性,非免疫抑制,这还没有在美国描述。38岁男性,有同性伴侣史,6周前出现新的口腔病变。他的人乳头瘤病毒和艾滋病毒感染呈阴性。计算机断层扫描(CT)显示硬腭的破坏性病变。活检标本与地方性KS一致。正电子发射断层扫描-计算机断层扫描(PET-CT)显示广泛转移性疾病。病例报告描述了一种罕见的hiv血清阴性KS亚型的男性与男性发生性行为。然而,这些是典型的惰性肿瘤,只有皮肤表现。这是一个独特的病例侵袭性,广泛转移地方性KS转移患者与hiv阴性。
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引用次数: 0
A Novel Classification System for the Anatomical Variations of the Infraorbital Ethmoidal (Haller) Air Cells. 眶下 Ethmoidal(Haller)气室解剖变异的新分类系统。
Pub Date : 2025-01-01 DOI: 10.1177/01455613241306947
Ahmed Ragab, Ayman Ali Abdelfattah Ali, Salem Ahmed Abd Elghany Yousef, Shaimaa Abdelhamid Hassanein, Anwar Abdelatty Ibrahim

Background: Infraorbital ethmoidal air cells (IOEAc) are ethmoidal cells that pneumatizes inferior to the orbital floor and lateral to a line parallel to the lamina papyracea. Studies have shown considerable anatomical variation with different extensions in humans. Objectives: To identify and categorize the anatomical variations of the IOEAc creating a new, comprehensive variation classification system. Patients and methods: All included 1260 computed tomography of the nose and paranasal sinuses were reviewed to detect the presence or absence of IOEAc. All cases with IOEAc were evaluated for bilaterality, multiplicity, and shape and categorized according to its extensions to the maxillary infundibulum and its relations to the entire length of the inferior orbital wall. Results: IOEAc were identified in 173 (13.7%) scans. Bilaterality was observed in 99 patients (57.2%), while 50 patients (28.9%) had unilateral air cells on the right and 24 patients (13.9%) had unilateral air cells on the left. They were classified into 5 categories that were subclassified into subtypes. With 173 cases distributed as 26%, 17.9%, 3.5%, 9.8%, 24.9%, 10.4%, 2.3%, 1.7%, and 3.5% among the 5 categories, respectively. Conclusions: The new classification system provides a comprehensive classification of the described anatomical variations of the IOEAc. It allows the description and categorization of variants identified in past and future studies. It is applicable to current clinical practice.

背景:眶下筛面空气细胞(IOEAc)是一种充气的筛面细胞,位于眶底下方,与纸莎草膜平行的一条线外侧。研究表明,在人类不同的延伸有相当大的解剖差异。目的:识别和分类IOEAc的解剖变异,建立一个新的,全面的变异分类系统。患者和方法:所有纳入的1260例鼻和鼻窦的计算机断层扫描检查是否存在IOEAc。所有的IOEAc病例都被评估为双侧性、多重性和形状,并根据其延伸到上颌窝及其与下眶壁全长的关系进行分类。结果:发现IOEAc 173例(13.7%)。双侧99例(57.2%),右侧单侧气细胞50例(28.9%),左侧单侧气细胞24例(13.9%)。它们被分为5类,再细分为亚型。173例,5类中分别占26%、17.9%、3.5%、9.8%、24.9%、10.4%、2.3%、1.7%、3.5%。结论:新的分类系统为所描述的IOEAc解剖变异提供了一个全面的分类。它允许对过去和未来研究中发现的变异进行描述和分类。适用于目前的临床实践。
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引用次数: 0
Recurrent Pleomorphic Adenoma Presenting as a Giant Parapharyngeal Mass. 复发性多形性腺瘤表现为巨大咽旁肿块。
Pub Date : 2025-01-01 DOI: 10.1177/01455613241312761
Rahaf Salam, Reem Ashreefa, Yasser Al Ghabra, Marah Nammourah, Mohammad Jomaa

Introduction: Pleomorphic adenoma (PA) is the most common benign salivary gland tumor, primarily found in the parotid gland. Recurrences often extend into the parapharyngeal space (PPS), complicating management. This report presents a case of a recurrent giant PA in the PPS following a limited excision. Case Description: A 45-year-old male presented with a gradually enlarging neck mass, dysphagia, and mild dyspnea, having previously undergone limited excision of a PA. Clinical examination revealed a firm mass in the right parotid region. Magnetic resonance imaging (MRI) showed a large mass in the right parapharyngeal space. Surgical excision was performed using a cervical-transparotid and mandibular swing approach. The patient was discharged after 7 days and later received radiotherapy. Discussion: Parapharyngeal space tumors (PPT) are rare neoplasms, with 70% to 80% being benign, primarily PAs. Symptoms include neck masses, swallowing difficulties, and potential cranial nerve involvement. MRI is crucial for assessing tumor extent. A combined transparotid-transcervical approach was employed. Postoperative radiotherapy was recommended. Conclusions: PPTs present significant clinical challenges, highlighting the need for meticulous surgical planning and complete excision of PAs to minimize recurrence risk. The close proximity of vital neurovascular structures requires careful preoperative evaluation and strategic surgical approaches.

多形性腺瘤(PA)是最常见的涎腺良性肿瘤,主要发生在腮腺。复发常延伸至咽旁间隙(PPS),使治疗复杂化。本报告报告一例在有限切除后PPS复发的巨大PA。病例描述:45岁男性,颈部肿块逐渐增大,吞咽困难,轻度呼吸困难,既往行局部PA切除。临床检查显示右侧腮腺区有一坚硬肿块。磁共振显示右侧咽旁间隙有一大肿块。手术切除采用颈-经腮腺和下颌摆动入路。患者于7天后出院,接受放疗。讨论:咽旁间隙肿瘤(PPT)是一种罕见的肿瘤,70% - 80%为良性,主要是PAs。症状包括颈部肿块、吞咽困难和潜在的脑神经受累。MRI是评估肿瘤范围的关键。采用经输卵管-经颈椎联合入路。建议术后放疗。结论:PPTs面临着重大的临床挑战,强调需要精心的手术计划和完全切除PAs以减少复发风险。靠近重要的神经血管结构需要仔细的术前评估和有策略的手术入路。
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引用次数: 0
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Ear, nose, & throat journal
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