Worldwide, one in eight deaths is due to cancer. Projections based on the GLOBOCAN 2012 estimates predict a substantive increase new cancer cases per year by 2035 in developing countries if preventive measures are not widely applied. According to the World Health Organization (WHO), millions of lives could be saved each year if countries made use of existing knowledge and the best cost-effective methods to prevent and treat cancer. Therefore, the aim of this study is to estimate a provisional budget against cancer in low and middle incomes countries, according the GNI-PPP, the cancer incidence and the number of population. Economically country classification is determining with the Gross national income (GNI), per capita, Purchasing power parity (PPP), according the administrations of the International Monetary Fund (IMF), the World Bank (WB) and the Central Intelligence Agency (CIA). Cancer incidence data presented are based on the most recent data available at IARC. However, population compares estimates from the US Bureau of the Census. The provisional budget is establishing among the guidelines developed by WHO for regional and national cancer control programs according to national economic development. Provisional budget against cancer is estimated to 8,110,095.41 (thousands of U.S $) for a population of 260,580,739 persons in Indonesia.
{"title":"Indonesia Program Against Cancer","authors":"E. Mbaye","doi":"10.47485/2767-5416.1025","DOIUrl":"https://doi.org/10.47485/2767-5416.1025","url":null,"abstract":"Worldwide, one in eight deaths is due to cancer. Projections based on the GLOBOCAN 2012 estimates predict a substantive increase new cancer cases per year by 2035 in developing countries if preventive measures are not widely applied. According to the World Health Organization (WHO), millions of lives could be saved each year if countries made use of existing knowledge and the best cost-effective methods to prevent and treat cancer. Therefore, the aim of this study is to estimate a provisional budget against cancer in low and middle incomes countries, according the GNI-PPP, the cancer incidence and the number of population. Economically country classification is determining with the Gross national income (GNI), per capita, Purchasing power parity (PPP), according the administrations of the International Monetary Fund (IMF), the World Bank (WB) and the Central Intelligence Agency (CIA). Cancer incidence data presented are based on the most recent data available at IARC. However, population compares estimates from the US Bureau of the Census. The provisional budget is establishing among the guidelines developed by WHO for regional and national cancer control programs according to national economic development. Provisional budget against cancer is estimated to 8,110,095.41 (thousands of U.S $) for a population of 260,580,739 persons in Indonesia.","PeriodicalId":94090,"journal":{"name":"Journal of medical clinical case reports","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90694717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: The objectives of this study were to assess the relationship between the third molar and the mandibular canal, to identify the radiographic markers most prevalent in predicting connectivity between these structures, and to associate these signs and proximity with the position of the third molar according to Bell, Gregory’s and Winter’s classifications. Subjects and methods: A retrospective cross-sectional study was conducted in the city of Sana’a on a sample of Yemeni patients in Ammar Dental Clinics who underwent panoramic radiography in the year 2019 until September 2020. The study consisted of panoramic radiographs of 597 patients with third molars with a total of 1017 third molars; the number of males was 216 (36.2%) and 381 females (63.8%). The panoramic radiographs were evaluated for proximity signs. Inclusion criteria were patients of both sexes who had at least a fully formed third molar of the mandible that was adjacent to the second molar. The radiographs were excluded if evidence of cystic, neoplastic, or extensive caries processes was detected. Seven radiological signs were used to determine if there was contact between the third molar and the mandibular canal. Results: A proximity to the mandibular canal was verified for 620 (61%) of 1017 third molars. The most frequent radiographic signs of proximity were darkened roots (315 teeth [31%]) and discontinuity of the mandibular canal (267 teeth [26.3%]). Third molar/mandibular canal proximity was found significantly more frequently in female patients and in patients aged 24 years and younger (P < 0.001). The tooth positions most frequently associated with proximity between the third molar and the mandibular canal were position C (highest point of the third molar located at or below the cervical margin of the second molar) and the mesioangular position (long axis of the third molar angled mesially toward the second molar). Conclusions: The frequency of third molar/ mandibular canal proximity was greater in female patients and patients aged 24 years or younger. The most frequently observed signs of proximity were darkening of the roots and discontinuity of the mandibular canal. The tooth positions most frequently associated with proximity of the third molar to the mandibular canal were position C and the mesioangular position.
{"title":"Panoramic Radiographic Analysis of Signs of Proximity to the Third Molar Roots of the Mandibular Canal in Yemen","authors":"","doi":"10.47485/2767-5416.1017","DOIUrl":"https://doi.org/10.47485/2767-5416.1017","url":null,"abstract":"Objectives: The objectives of this study were to assess the relationship between the third molar and the mandibular canal, to identify the radiographic markers most prevalent in predicting connectivity between these structures, and to associate these signs and proximity with the position of the third molar according to Bell, Gregory’s and Winter’s classifications. Subjects and methods: A retrospective cross-sectional study was conducted in the city of Sana’a on a sample of Yemeni patients in Ammar Dental Clinics who underwent panoramic radiography in the year 2019 until September 2020. The study consisted of panoramic radiographs of 597 patients with third molars with a total of 1017 third molars; the number of males was 216 (36.2%) and 381 females (63.8%). The panoramic radiographs were evaluated for proximity signs. Inclusion criteria were patients of both sexes who had at least a fully formed third molar of the mandible that was adjacent to the second molar. The radiographs were excluded if evidence of cystic, neoplastic, or extensive caries processes was detected. Seven radiological signs were used to determine if there was contact between the third molar and the mandibular canal. Results: A proximity to the mandibular canal was verified for 620 (61%) of 1017 third molars. The most frequent radiographic signs of proximity were darkened roots (315 teeth [31%]) and discontinuity of the mandibular canal (267 teeth [26.3%]). Third molar/mandibular canal proximity was found significantly more frequently in female patients and in patients aged 24 years and younger (P < 0.001). The tooth positions most frequently associated with proximity between the third molar and the mandibular canal were position C (highest point of the third molar located at or below the cervical margin of the second molar) and the mesioangular position (long axis of the third molar angled mesially toward the second molar). Conclusions: The frequency of third molar/ mandibular canal proximity was greater in female patients and patients aged 24 years or younger. The most frequently observed signs of proximity were darkening of the roots and discontinuity of the mandibular canal. The tooth positions most frequently associated with proximity of the third molar to the mandibular canal were position C and the mesioangular position.","PeriodicalId":94090,"journal":{"name":"Journal of medical clinical case reports","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75742576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: Breast hamartoma is a rare painless benign tumor with limited literature review due to underestimation by clinicians and pathologists. Though slowly growing, delay in diagnosis can lead to physical and psychological impact due to breast size discrepancy. Our study intend was to present breast hamartoma concerning size variance from hardly palpable to gross defacement and its psychosocial impact due to physical disfigurement, along with a case report. Method: We reviewed the demographic data, radiological imaging, and size variability of patients diagnosed with breast hamartoma between May 2006 and November 2019. Results: Overall, 37 cases of female breast hamartoma were operated from 2006 to 2019 but only 20 cases, whose data can be retrieved, in Liaquat National Hospital & Medical College, Karachi Department of General Surgery were included in the study. The mean age of patients was 35±11.92 years. The clinical and histopathological size was 6.12 ±4.44 and 7.88 ±4.23 respectively. Largest recorded size was 20x20cm. There are 65% of cases with less than 40 years and 35% cases with greater than 45 years. Breast ultrasound and Mammograms were performed below 40 years and greater than 40 years age of respectively. Furthermore, one case presented with skin necrosis and necrotizing wound infection underwent wound debridement and later on reduction mammoplasty with hamartoma excision of 2.5 kg. Conclusion: Breast hamartomas are rare benign lesions that may have rapid growth leading to breast disfigurement and must be addressed vigilantly either by close observation or early intervention. Ultrasound has a significant role in diagnosis whereas the role of fine-needle aspiration is questionable.
{"title":"Breast Hamartoma: A Size Diversity with Psychosocial Impact Analysis of 20 Cases and an Exceptional Case Report Review","authors":"","doi":"10.47485/2767-5416.1016","DOIUrl":"https://doi.org/10.47485/2767-5416.1016","url":null,"abstract":"Objectives: Breast hamartoma is a rare painless benign tumor with limited literature review due to underestimation by clinicians and pathologists. Though slowly growing, delay in diagnosis can lead to physical and psychological impact due to breast size discrepancy. Our study intend was to present breast hamartoma concerning size variance from hardly palpable to gross defacement and its psychosocial impact due to physical disfigurement, along with a case report. Method: We reviewed the demographic data, radiological imaging, and size variability of patients diagnosed with breast hamartoma between May 2006 and November 2019. Results: Overall, 37 cases of female breast hamartoma were operated from 2006 to 2019 but only 20 cases, whose data can be retrieved, in Liaquat National Hospital & Medical College, Karachi Department of General Surgery were included in the study. The mean age of patients was 35±11.92 years. The clinical and histopathological size was 6.12 ±4.44 and 7.88 ±4.23 respectively. Largest recorded size was 20x20cm. There are 65% of cases with less than 40 years and 35% cases with greater than 45 years. Breast ultrasound and Mammograms were performed below 40 years and greater than 40 years age of respectively. Furthermore, one case presented with skin necrosis and necrotizing wound infection underwent wound debridement and later on reduction mammoplasty with hamartoma excision of 2.5 kg. Conclusion: Breast hamartomas are rare benign lesions that may have rapid growth leading to breast disfigurement and must be addressed vigilantly either by close observation or early intervention. Ultrasound has a significant role in diagnosis whereas the role of fine-needle aspiration is questionable.","PeriodicalId":94090,"journal":{"name":"Journal of medical clinical case reports","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87356786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The global Covid-19 pandemic and cross-contamination in hospitals has led to a serious public health problem and severe economic consequences [1]. As the Coronavirus panic continues to spread across the world, engineers and scientists are working hard to find new ways of developing novel respiratory protective devices. In the context of this prevention, the creation of antimicrobial textiles for medical applications (masks, gloves, surgical gowns …) appears an urgent necessity to fight against infections caused by pathogenic viruses and bacteria. Antimicrobial agents are molecules with the ability to kill microorganisms (biocides) or prevent their growth (biostatics). There are many antimicrobial molecules that can be used for the functionalization of textiles, the most widely used in the field of textiles are triclosan and its derivatives, zeolites (silver and copper or silver and zinc aluminosilicates), quaternary ammoniums, mineral powders (silver and copper), phenols, polyphenols, chitosan, silver ions, antimicrobial peptides and lytic enzymes [2-5].
{"title":"Respiratory Protective Textile Devices Based on Immobilized Biocidal Enzymes and Peptides: A Spirit of Innovation","authors":"","doi":"10.47485/2767-5416.1014","DOIUrl":"https://doi.org/10.47485/2767-5416.1014","url":null,"abstract":"The global Covid-19 pandemic and cross-contamination in hospitals has led to a serious public health problem and severe economic consequences [1]. As the Coronavirus panic continues to spread across the world, engineers and scientists are working hard to find new ways of developing novel respiratory protective devices. In the context of this prevention, the creation of antimicrobial textiles for medical applications (masks, gloves, surgical gowns …) appears an urgent necessity to fight against infections caused by pathogenic viruses and bacteria. Antimicrobial agents are molecules with the ability to kill microorganisms (biocides) or prevent their growth (biostatics). There are many antimicrobial molecules that can be used for the functionalization of textiles, the most widely used in the field of textiles are triclosan and its derivatives, zeolites (silver and copper or silver and zinc aluminosilicates), quaternary ammoniums, mineral powders (silver and copper), phenols, polyphenols, chitosan, silver ions, antimicrobial peptides and lytic enzymes [2-5].","PeriodicalId":94090,"journal":{"name":"Journal of medical clinical case reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73858238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This report describes the case of a 39-year-old man with a mediastinal teratoma. For seven years the patient had been suffering a dyspnea on exertion. In the last few weeks, the dyspnea increased and new symptoms appeared such as dry cough, chest pain and palpitations. Computed tomography revealed a medium-sized tumor that was markedly compressing the superior vena cava and the right atrium. Surgery was performed, and a benign mature teratoma was diagnosed. Mature mediastinal teratomas are benign tumors, but they can be adherent to collateral structures in the chest leading to life threatening complications.
{"title":"Slow-Growing Mature Mediastinal Teratoma: Case Report","authors":"","doi":"10.47485/2767-5416.1013","DOIUrl":"https://doi.org/10.47485/2767-5416.1013","url":null,"abstract":"This report describes the case of a 39-year-old man with a mediastinal teratoma. For seven years the patient had been suffering a dyspnea on exertion. In the last few weeks, the dyspnea increased and new symptoms appeared such as dry cough, chest pain and palpitations. Computed tomography revealed a medium-sized tumor that was markedly compressing the superior vena cava and the right atrium. Surgery was performed, and a benign mature teratoma was diagnosed. Mature mediastinal teratomas are benign tumors, but they can be adherent to collateral structures in the chest leading to life threatening complications.","PeriodicalId":94090,"journal":{"name":"Journal of medical clinical case reports","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73343025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Authors report the unusual epidemiological features of the COVID 19 in an area of the Northern Italy. The reasons of the lower prevalence compared to other areas are described. A set of strategies have proven successful in limiting cases.
{"title":"COVID-19 in eastern Emilia: an unusual epidemiology in Northern Italy","authors":"M. Libanore, D. Segala, Enrico Biagi, R. Cultrera","doi":"10.47485/2767-5416.1012","DOIUrl":"https://doi.org/10.47485/2767-5416.1012","url":null,"abstract":"The Authors report the unusual epidemiological features of the COVID 19 in an area of the Northern Italy. The reasons of the lower prevalence compared to other areas are described. A set of strategies have proven successful in limiting cases.","PeriodicalId":94090,"journal":{"name":"Journal of medical clinical case reports","volume":"77 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91536745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
If it is true that covid-19 comes from wild animals that have lost their natural habitat due to deforestation and large forest fires and savannas; if it is true that the mortality of those affected increases exponentially in the areas with higher percentages of fine dust, Nox, Sox, CO, in the atmosphere; if it is true that the most affected are the elderly, what does this have to do with the European call for startups dedicated to the Covid-19 emergency, which expired on 18 March, intended above all for small and medium-sized enterprises for innovative contributions useful for cope with any aspect of the emergency? The budget for this call is 164 million euros. What is this rain of millions on small and medium-sized enterprises? At most, they can develop some control and monitoring software for people who move around the area. This is already being done in China and Korea. Since we are late, we may also be able to import this software from these countries. Why, as Europeans, do we not focus on the real problem that affects the entire world development? Emerging countries, such as China and Korea, have made the mistake of copying our energy and purification solutions, even surpassing us by the amount of pollution produced. EUROPE should anticipate the immediate decarburization of energy, the modification of urban purification systems (we cannot continue to wait for the rains to reduce fine particles).
{"title":"We will not Get Rid of Coronaviruses without Creating a True Sustainable Development Model","authors":"","doi":"10.47485/2767-5416.1011","DOIUrl":"https://doi.org/10.47485/2767-5416.1011","url":null,"abstract":"If it is true that covid-19 comes from wild animals that have lost their natural habitat due to deforestation and large forest fires and savannas; if it is true that the mortality of those affected increases exponentially in the areas with higher percentages of fine dust, Nox, Sox, CO, in the atmosphere; if it is true that the most affected are the elderly, what does this have to do with the European call for startups dedicated to the Covid-19 emergency, which expired on 18 March, intended above all for small and medium-sized enterprises for innovative contributions useful for cope with any aspect of the emergency? The budget for this call is 164 million euros. What is this rain of millions on small and medium-sized enterprises? At most, they can develop some control and monitoring software for people who move around the area. This is already being done in China and Korea. Since we are late, we may also be able to import this software from these countries. Why, as Europeans, do we not focus on the real problem that affects the entire world development? Emerging countries, such as China and Korea, have made the mistake of copying our energy and purification solutions, even surpassing us by the amount of pollution produced. EUROPE should anticipate the immediate decarburization of energy, the modification of urban purification systems (we cannot continue to wait for the rains to reduce fine particles).","PeriodicalId":94090,"journal":{"name":"Journal of medical clinical case reports","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84413878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-05-18DOI: 10.47485/2767-5416.10010
Aamir Jalal Al-Mosawi
There are four genera of coronaviruses including α-coronaviruses, β-coronaviruses, γ-coronaviruses, and δ-coronaviruses. α and β-coronavirus can infect mammals, while γ-coronavirus and δ-coronavirus generally infect birds. Four coronaviruses are known to cause mild upper respiratory infection in humans of all ages including infants. The transmission of coronaviruses from animals (birds) to causes respiratory illness has been reported as early as 1969 by Kapikian et al. Communitywide outbreak associated with 229E-like coronavirus has be reported as early as 1970 by Cavallaro and Monto [1-7].
{"title":"Bat-Human Coronaviruses: A Global Health Problem and a Therapeutic Challenge","authors":"Aamir Jalal Al-Mosawi","doi":"10.47485/2767-5416.10010","DOIUrl":"https://doi.org/10.47485/2767-5416.10010","url":null,"abstract":"There are four genera of coronaviruses including α-coronaviruses, β-coronaviruses, γ-coronaviruses, and δ-coronaviruses. α and β-coronavirus can infect mammals, while γ-coronavirus and δ-coronavirus generally infect birds. Four coronaviruses are known to cause mild upper respiratory infection in humans of all ages including infants. The transmission of coronaviruses from animals (birds) to causes respiratory illness has been reported as early as 1969 by Kapikian et al. Communitywide outbreak associated with 229E-like coronavirus has be reported as early as 1970 by Cavallaro and Monto [1-7].","PeriodicalId":94090,"journal":{"name":"Journal of medical clinical case reports","volume":"97 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90262868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Over the past two decades, the incidence of the kidney cancer has increased by 2% worldwide. It will appear in the VI-VII decade of life (average age 60 years). Kidney cancer was previously considered to be an older person’s disease, however according to the world health organization 2017; the number of young people with kidney cancer has unfortunately increased. Most of renal malignancies are so called renal-cell carcinoma (RCC) [1]. As for kidney, sarcoma and Wilms tumor are much rear.
{"title":"Administration of Infrared Transillumination Method for Improving Diagnostic Outcomes of the Partial Nephrectomy","authors":"","doi":"10.47485/2767-5416.1009","DOIUrl":"https://doi.org/10.47485/2767-5416.1009","url":null,"abstract":"Over the past two decades, the incidence of the kidney cancer has increased by 2% worldwide. It will appear in the VI-VII decade of life (average age 60 years). Kidney cancer was previously considered to be an older person’s disease, however according to the world health organization 2017; the number of young people with kidney cancer has unfortunately increased. Most of renal malignancies are so called renal-cell carcinoma (RCC) [1]. As for kidney, sarcoma and Wilms tumor are much rear.","PeriodicalId":94090,"journal":{"name":"Journal of medical clinical case reports","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88887344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Since 2009, there has been a serious increase in the number of meningococcal infections in Europe caused by the serotype W meningococcus (MenW:cc11). Invasive meningococcal disease is typically known to cause severe sepsis or meningitiswith high overall mortality rates of 10% despite adequate antimicrobial treatment. Focal infections such as arthritis incidentally occur as a complication of systemic disease. Method We describe a rare case of primary meningococcal W135 arthritis in a 2-year-old patient. Results Arthrocentesis of the right Ankle while patient was under anesthesia, yielded grossly purulent fluid, so we made arthrotomy and drainage. The culture from synovial fluid revealed N. meningitidis.The status of the patient improved after surgical drainage and intravenous antibiotic therapy. She recovered completely after 1 month. Discussion.Atypical clinical presentation is associated with higher case fatality rates and can lead to misdiagnoses.an unusual presentation of invasive meningococcal infection and the early identification of the bacteria, combined with the correct treatment, prevent the complications and even death.
{"title":"Neisseira meningitidis Serogroup W causing primary meningococcal septic arthritis in a toddler and review of the literature","authors":"","doi":"10.47485/2767-5416.1008","DOIUrl":"https://doi.org/10.47485/2767-5416.1008","url":null,"abstract":"Since 2009, there has been a serious increase in the number of meningococcal infections in Europe caused by the serotype W meningococcus (MenW:cc11). Invasive meningococcal disease is typically known to cause severe sepsis or meningitiswith high overall mortality rates of 10% despite adequate antimicrobial treatment. Focal infections such as arthritis incidentally occur as a complication of systemic disease. Method We describe a rare case of primary meningococcal W135 arthritis in a 2-year-old patient. Results Arthrocentesis of the right Ankle while patient was under anesthesia, yielded grossly purulent fluid, so we made arthrotomy and drainage. The culture from synovial fluid revealed N. meningitidis.The status of the patient improved after surgical drainage and intravenous antibiotic therapy. She recovered completely after 1 month. Discussion.Atypical clinical presentation is associated with higher case fatality rates and can lead to misdiagnoses.an unusual presentation of invasive meningococcal infection and the early identification of the bacteria, combined with the correct treatment, prevent the complications and even death.","PeriodicalId":94090,"journal":{"name":"Journal of medical clinical case reports","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75514627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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