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Monitoring emergency and urgent surgery: an improvement in a Healthcare Management Unit at a third-level hospital in Italy. 监控急诊和紧急手术:意大利一家三级医院医疗管理部门的改进。
Pub Date : 2024-08-31 eCollection Date: 2024-06-01 DOI: 10.15167/2421-4248/jpmh2024.65.2.3161
Lucia Inglese, Ilaria Barberis, Mariia Korshunova, Rosa Amato, Francesca Zangrillo, Lucia Arata, Valentino Tisa, Riccardo Papalia, Maurizio Santo, Gabriella Tiberio, Alessandra Morando, Giovanni Orengo

Introduction: At San Martino IRCCS Hospital in Genoa, Italy, emergency and urgent surgery is classified according to the National Confidential Enquiry into Patient Outcome and Death (NCEPOD) classification, whereby cases are divided into two categories and colour-coded accordingly: - EMERGENCY - (Colour-code: RED) "Surgery to be performed within minutes"; - URGENCY - (colour-code: YELLOW) "Surgery to be performed within hours". In this context, it is essential that the emergency surgical team gets clear and complete information from the proposing surgeon, in order to complete the surgical list.

Methods: Between 14th April 2023 and 23th July 2023, a new method of requesting urgent and emergency surgery by filling out an online form was tested.

Results: A total of 406 online requests were made, resulting in 367 E/U surgeries. The greatest number of emergency operations concerned thoracic-abdominal surgery (45%), followed by urology (19%). The requests analysed classified 18% of cases as red and 71% as yellow. The remaining 11% contained compilation errors. Moreover, 11% of the interventions were not performed within the time limits defined according to the severity code.

Conclusions: By means of this new tool, San Martino IRCCS Hospital's Healthcare Management Unit can monitor requests for surgery in real time, thereby achieving greater efficiency and implementing corrective measures in the use of Operating Room resources.

简介在意大利热那亚的圣马蒂诺 IRCCS 医院,急诊和紧急手术是根据 "全国病人结果和死亡保密调查"(NCEPOD)分类法进行的,根据该分类法,病例被分为两类,并以相应的颜色编码:- 急诊--(颜色代码:红色)"需在几分钟内进行的手术"; - 紧急--(颜色代码:黄色)"需在几小时内进行的手术"。在这种情况下,急诊外科团队必须从提议手术的外科医生处获得清晰完整的信息,以便完成手术清单:方法:2023 年 4 月 14 日至 2023 年 7 月 23 日期间,测试了通过填写在线表格申请紧急和急诊手术的新方法:结果:共收到 406 份在线申请,完成了 367 例急诊手术。最多的急诊手术涉及胸腹外科(45%),其次是泌尿外科(19%)。所分析的申请中,18%的病例被列为红色病例,71%的病例被列为黄色病例。其余 11% 的病例存在编辑错误。此外,有 11% 的干预未在根据严重程度代码确定的时限内进行:通过这一新工具,圣马蒂诺IRCCS医院的医疗管理部门可以实时监控手术申请,从而提高效率,并在手术室资源的使用方面采取纠正措施。
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引用次数: 0
Comparison of the short-term effect of intra-articular hyaluronic acid and platelet-rich plasma injections in knee osteoarthritis: a randomized clinical trial. 膝关节骨关节炎患者关节内注射透明质酸和富含血小板血浆的短期疗效比较:随机临床试验。
Pub Date : 2024-08-31 eCollection Date: 2024-06-01 DOI: 10.15167/2421-4248/jpmh2024.65.2.3270
Omid Ghorbani, Daryoosh Mahdibarzi, Paria Yousefi-Tooddeshki

Introduction: Osteoarthritis (OA) is one of the most common degenerative joint diseases which involved all joints. It is very important to choose a treatment method with high efficiency to reduce the pain and disability of patients and also to improve their quality of life. The current study aimed to investigate the therapeutic effects of intra-articular injection of PRP and hyaluronic acid (HA) in the knee of people with knee osteoarthritis (KOA).

Methods: In this randomized clinical trial study, 90 patients with KOA were randomly divided into two groups of intra-articular HA and PRP. The patients of the two groups were followed up for five months and different outcomes were recorded. The McMaster index (WOMAC) evaluated all patients at rest and during movements. Measurements were taken at the beginning and after the third month of follow-up.

Results: Three month after the last injection (5th month) and after adjusting of baseline value using analysis of covariance, the mean of knee pain, stiffness, physical function and finally total score in the PRP group, was significantly lower than the HA group. Regarding the Osteoarthritis grade, the mean of knee pain, Stiffness, Physical function and finally total score in the PRP group was significantly lower than the HA group in all Osteoarthritis grades. Also, there were no complications in the studied groups.

Conclusions: The results of the current study showed that pain and stiffness reduction as well as physical function of the knee joint in the PRP group was better than in the HA group.

导言骨关节炎(OA)是最常见的退行性关节疾病之一,涉及所有关节。选择一种高效的治疗方法来减轻患者的疼痛和残疾,并提高他们的生活质量非常重要。本研究旨在探讨膝关节骨性关节炎(KOA)患者膝关节内注射 PRP 和透明质酸(HA)的治疗效果:在这项随机临床试验研究中,90 名 KOA 患者被随机分为两组,分别接受 HA 和 PRP 的关节内注射。对两组患者进行了为期五个月的随访,并记录了不同的结果。麦克马斯特指数(WOMAC)评估了所有患者在休息和运动时的情况。在随访开始和第三个月后进行了测量:结果:最后一次注射三个月后(第五个月),在使用协方差分析调整基线值后,PRP 组的膝关节疼痛、僵硬、身体功能和总分的平均值明显低于 HA 组。就骨关节炎等级而言,在所有骨关节炎等级中,PRP 组膝关节疼痛、僵硬度、身体功能和总分的平均值均明显低于 HA 组。此外,各研究组均未出现并发症:本研究结果表明,PRP 组的膝关节疼痛和僵硬度减轻程度以及身体功能均优于 HA 组。
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引用次数: 0
Violence against healthcare workers during the phases of the COVID-19 Pandemic: a descriptive observational study from 2018 to 2023 in the metropolitan city of Genoa (North-Western Italy). COVID-19 大流行期间针对医护人员的暴力行为:2018 年至 2023 年热那亚大都市(意大利西北部)的描述性观察研究。
Pub Date : 2024-08-31 eCollection Date: 2024-06-01 DOI: 10.15167/2421-4248/jpmh2024.65.2.3143
Gloria Spatari, Anna Maria Libera DE Mite, Elisa Cantova, Silvia Reggiani, Michela Re, Michelangelo Mercogliano, Maria DE Martini, Nadia Casanova, Alessandro Gallo, Marta Caltabellotta, Bruna Rebagliati

Background: Violence against healthcare workers is an escalating public health concern, affecting the quality of care, and causing significant psychological and physical effects on healthcare professionals. This study analysed the trend in aggressions in healthcare settings in the pre-pandemic, pandemic, and post-pandemic periods.

Methods: An observational descriptive study was conducted to analyse reports of violence against healthcare workers from January 2018 to June 2023 at a Local Health Authority "ASL3" in the Liguria region of Italy. The study considered variables such as the severity of aggression, professional category involved, and location of incident. Episodes of violence were classified according to severity by means of a colour-coded system. We used multinomial logistic regression to examine any associations between the pandemic phase and the various factors, while controlling for relevant variables.

Results: The number of reported aggressions rose from 48 in 2018 to 90 in 2022, with a partial count of 35 in the first half of 2023. The pandemic phase saw a rise in incidents classified as Green codes, which accounted for 58.3%, and a significant involvement of District Services. The post-pandemic phase showed a reversion to pre-pandemic levels but with an increase in Yellow codes (5.6%). Nurses were the most frequent victims, with figures ranging from 50.8% to 95.6% over the years. The Emergency Department and Psychiatric Services emerged as the most critical settings of aggressions, with incidents recorded in these areas constituting over half of the total number. However, an increase in violence was also recorded in district healthcare settings during the post-pandemic phase.

Conclusions: There is an urgent need for comprehensive strategies for the prevention of violence in healthcare settings. The increasing trend in violence, especially during the pandemic, necessitates integrated approaches that encompass training, psychological support, security policies, and a strong organizational culture to promote safety and respect. Protecting healthcare workers is crucial to their wellbeing and the quality of healthcare delivery.

背景:针对医护人员的暴力行为是一个日益严重的公共卫生问题,它影响了医疗质量,并对医护人员的心理和身体造成了严重影响。本研究分析了大流行前、大流行期间和大流行后医疗机构中侵害行为的趋势:本研究是一项观察性描述研究,旨在分析意大利利古里亚大区地方卫生局 "ASL3 "在 2018 年 1 月至 2023 年 6 月期间针对医护人员的暴力事件报告。研究考虑了侵害的严重程度、涉及的专业类别和事件发生地点等变量。暴力事件根据严重程度用颜色编码系统进行分类。我们使用多项式逻辑回归法来研究大流行阶段与各种因素之间的关联,同时控制相关变量:报告的侵害事件数量从 2018 年的 48 起上升到 2022 年的 90 起,2023 年上半年的部分数量为 35 起。在大流行阶段,被归类为绿色代码的事件有所增加,占 58.3%,地区服务部门也大量参与其中。大流行后的阶段则恢复到大流行前的水平,但黄色代码事件有所增加(5.6%)。护士是最常见的受害者,多年来占 50.8%至 95.6%不等。急诊科和精神科是发生侵犯事件最严重的场所,在这些场所发生的事件占总数的一半以上。然而,在大流行后阶段,地区医疗机构中的暴力事件也有所增加:结论:迫切需要制定全面的策略来预防医疗机构中的暴力行为。特别是在大流行期间,暴力事件呈上升趋势,因此有必要采取综合方法,包括培训、心理支持、安全政策和强有力的组织文化,以促进安全和尊重。保护医护人员对他们的健康和医疗服务质量至关重要。
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引用次数: 0
A new organizational model of primary healthcare in Liguria, Italy. Insights and implications. 意大利利古里亚初级医疗保健的新组织模式。见解和影响。
Pub Date : 2024-08-31 eCollection Date: 2024-06-01 DOI: 10.15167/2421-4248/jpmh2024.65.2.3145
Filippo Ansaldi, Matteo Astengo, Alberto Battaglini, Federico Grammatico, Francesca Marchini, Andrea Fiorano, Silvia Allegretti, Irene Schenone, Daniela Amicizia

After years of cost-containment policies, the Italian National Health Service (NHS) has now the chance to change and improve, especially thanks to the National Recovery and Resilience Plan (NRRP). The plan serves as a catalyst for reform, allocating substantial funds to reinforce proximity networks, facilities, and telemedicine for territorial healthcare. Mission 6, specifically dedicated to health, focuses on integrating primary healthcare, hospital, and specialty care networks, underscoring the importance of a robust primary healthcare system. In alignment with NRRP objectives, the Ligurian model introduces innovative structures, such as Community Houses (CdCs), Community Hospitals (OdCs), and Territorial Operation Centres (COTs). These interconnected components form a dynamic network designed to enhance healthcare accessibility, prevent inappropriate hospital admissions, and facilitate efficient patient transitions. The model prioritizes multidisciplinary collaboration, community engagement, and the integration of socio-healthcare services. Despite substantial NRRP funding for infrastructure, challenges related to staffing and human resources persist. The social and epidemiological context highlights concern about the economic feasibility of the reform, potential workforce shortages, and the imperative for updated regulatory frameworks. The strategic reallocation of personnel from acute hospitals to new facilities is crucial, requiring meticulous workforce planning, role definitions, and trainingIn conclusion, the Ligurian model emerges as a proactive response to the structural vulnerabilities exposed by the pandemic, aligning with international trends in emphasizing primary care, prevention, and community-based services.

在多年的成本控制政策之后,意大利国家医疗服务体系(NHS)现在有了改变和改进的机会,这尤其要归功于国家恢复和复原计划(NRRP)。该计划是改革的催化剂,划拨了大量资金用于加强近距离网络、设施和远程医疗,以促进地区医疗保健。任务 6 专门针对卫生保健,重点是整合初级保健、医院和专科护理网络,强调健全的初级保健系统的重要性。为与 NRRP 目标保持一致,利古里亚模式引入了创新结构,如社区之家 (CdCs)、社区医院 (OdCs) 和地区运营中心 (COTs)。这些相互关联的组成部分形成了一个动态网络,旨在提高医疗服务的可及性,防止不适当的入院治疗,并促进病人的有效转院。该模式优先考虑多学科协作、社区参与和社会医疗服务一体化。尽管国家康复计划为基础设施提供了大量资金,但人员配备和人力资源方面的挑战依然存在。社会和流行病学背景凸显了人们对改革的经济可行性、潜在的劳动力短缺以及更新监管框架的必要性的担忧。总之,利古里亚模式是对大流行病暴露出的结构性弱点的积极应对,与强调初级保健、预防和社区服务的国际趋势相一致。
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引用次数: 0
Impact of gender and education on cervical cancer knowledge amongst students: implications for health policies and public health strategies in Wiesbaden, Germany. 性别和教育对学生宫颈癌知识的影响:对德国威斯巴登卫生政策和公共卫生战略的启示。
Pub Date : 2024-08-31 eCollection Date: 2024-06-01 DOI: 10.15167/2421-4248/jpmh2024.65.2.3077
Harry Gymah Gyamfi

Introduction: Cervical cancer is a global health concern primarily caused by human papillomavirus (HPV). It has a significant impact in Germany, with thousands of new diagnoses and deaths annually. Despite advancements in screening and treatment leading to improved survival rates of 65% for invasive cervical tumors, the financial burden remains substantial.

Aims: The study aims to assess the impact of gender and education of Wiesbaden students towards cervical cancer and its associated health policies. Data was collected through an online questionnaire distributed with 54 students in Wiesbaden, Germany participating in the study. Statistical analysis was performed using SPSS, including one-way ANOVA, t-tests, Kruskal-Wallis, and chi-square tests. The respondents' average age was 28.24 years, with a higher female participation.

Results: Education level did not significantly influence perceptions of ideal vaccination age (p < 0.581). Females and males perceived a lower number of vaccine doses (< 3) required compared to the standard. Education level showed a moderate association with knowledge of long-term complications, and gender had a moderate correlation with information sources (rho = 27, p = 0.090).

Conclusion: Gender disparities did not significantly impact knowledge of cervical cancer. Public health programs should consider education levels and tailor interventions to all age groups and genders.

导言:宫颈癌是一个全球关注的健康问题,主要由人类乳头瘤病毒(HPV)引起。宫颈癌对德国的影响很大,每年新增数千例诊断和死亡病例。尽管在筛查和治疗方面取得了进步,使浸润性宫颈肿瘤的存活率提高到 65%,但经济负担依然沉重。研究通过在线问卷收集数据,德国威斯巴登的 54 名学生参与了研究。使用 SPSS 进行了统计分析,包括单因素方差分析、t 检验、Kruskal-Wallis 检验和卡方检验。受访者的平均年龄为 28.24 岁,女性参与率较高:受教育程度对理想接种年龄的看法没有明显影响(p < 0.581)。女性和男性认为所需的疫苗剂量(小于 3 剂)低于标准。教育水平与长期并发症知识呈中度相关,性别与信息来源呈中度相关(rho = 27,p = 0.090):结论:性别差异对宫颈癌知识的了解没有明显影响。公共卫生项目应考虑教育水平,并针对所有年龄组和性别采取相应的干预措施。
{"title":"Impact of gender and education on cervical cancer knowledge amongst students: implications for health policies and public health strategies in Wiesbaden, Germany.","authors":"Harry Gymah Gyamfi","doi":"10.15167/2421-4248/jpmh2024.65.2.3077","DOIUrl":"10.15167/2421-4248/jpmh2024.65.2.3077","url":null,"abstract":"<p><strong>Introduction: </strong>Cervical cancer is a global health concern primarily caused by human papillomavirus (HPV). It has a significant impact in Germany, with thousands of new diagnoses and deaths annually. Despite advancements in screening and treatment leading to improved survival rates of 65% for invasive cervical tumors, the financial burden remains substantial.</p><p><strong>Aims: </strong>The study aims to assess the impact of gender and education of Wiesbaden students towards cervical cancer and its associated health policies. Data was collected through an online questionnaire distributed with 54 students in Wiesbaden, Germany participating in the study. Statistical analysis was performed using SPSS, including one-way ANOVA, t-tests, Kruskal-Wallis, and chi-square tests. The respondents' average age was 28.24 years, with a higher female participation.</p><p><strong>Results: </strong>Education level did not significantly influence perceptions of ideal vaccination age (p < 0.581). Females and males perceived a lower number of vaccine doses (< 3) required compared to the standard. Education level showed a moderate association with knowledge of long-term complications, and gender had a moderate correlation with information sources (rho = 27, p = 0.090).</p><p><strong>Conclusion: </strong>Gender disparities did not significantly impact knowledge of cervical cancer. Public health programs should consider education levels and tailor interventions to all age groups and genders.</p>","PeriodicalId":94106,"journal":{"name":"Journal of preventive medicine and hygiene","volume":"65 2","pages":"E227-E231"},"PeriodicalIF":0.0,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11487726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trend of accesses to the Emergency Department of a Teaching Hospital of Tuscany due to bronchiolitis in 2018-2023: new challenges. 2018-2023 年托斯卡纳一家教学医院急诊科因支气管炎就诊的趋势:新挑战。
Pub Date : 2024-08-31 eCollection Date: 2024-06-01 DOI: 10.15167/2421-4248/jpmh2024.65.2.3204
Elena Capitani, Claudia Basagni, Emanuela Barbini, Carlotta Lorenzini, Maria Francesca DE Marco, Ilaria Manini, Emanuele Montomoli, Nicola Nante

Introduction: Acute bronchiolitis is one of leading causes of lower respiratory tract infection and hospitalisation in children less than one year old worldwide. The aim of our study is investigating the impact of bronchiolitis in children paediatric to the Emergency Department (ED) of Teaching Hospital (AOUS), Santa Maria alle Scotte of Siena, Tuscany (Italy).

Methods: A retrospective observational study was conducted on the accesses performed at the ED of the AOUS of Siena by children under 18 years of age suffering from bronchiolitis from September 2018 to April 2023.

Results: There were 36,031 patients between 0 and 18 years old in the Emergency Department, 383 of which presented bronchiolitis (age 4.8 months C.I.:3.5-6 months.; 54% male). Those who accessed the ED with a higher priority code were more likely to be subsequently admitted (O.R.:2.6; C.I.:1.3-5.1; p < 0.01). Those who accessed the ED with symptoms of bronchiolitis during the weekend were less likely to have been sent from community medicine services or professionals (O.R:0.1; C.I:0.0-0.5; p < 0.001). Children below 1 year old were more likely to access the ED with respiratory distress symptoms (O.R.:2.6; C.I.:1.5-4.3; p < 0.001). Finally, those who accessed the ED with bronchiolitis were more likely to be admitted than those who accessed for other conditions (O.R:24.5; C.I.:19.4-31; p < 0.001).

Conclusions: It is necessary to invest protocols integrating hospital services and community medicine in order to achieve a timely diagnosis and to reduce the accesses to the ED of children presenting mild, non-severe form of bronchiolitis in order to avoid the overload of hospital services.

导言:急性支气管炎是导致全球一岁以下儿童下呼吸道感染和住院治疗的主要原因之一。我们的研究旨在调查儿童支气管炎对意大利托斯卡纳锡耶纳圣玛丽亚斯科特教学医院急诊科(AOUS)的影响:方法:对2018年9月至2023年4月期间在锡耶纳AOUS医院急诊科就诊的18岁以下支气管炎患儿进行回顾性观察研究:急诊科共接诊 36031 名 0 至 18 岁患者,其中 383 人患有支气管炎(年龄为 4.8 个月 C.I.:3.5-6 个月;54% 为男性)。在急诊室就诊的儿童中,优先级代码较高的儿童更有可能随后入院(O.R.:2.6;C.I.:1.3-5.1;P < 0.01)。在周末出现支气管炎症状并前往急诊室就诊的儿童不太可能是由社区医疗服务机构或专业人员送来的(O.R:0.1;C.I:0.0-0.5;P < 0.001)。1 岁以下儿童更有可能因呼吸困难症状前往急诊室(O.R.:2.6;C.I.:1.5-4.3;p < 0.001)。最后,因支气管炎进入急诊室的患者比因其他疾病进入急诊室的患者更有可能入院(O.R:24.5;C.I.:19.4-31;p < 0.001):有必要制定医院服务与社区医疗相结合的方案,以实现及时诊断,并减少轻度、非严重支气管炎患儿进入急诊室的次数,从而避免医院服务负担过重。
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引用次数: 0
The modernity of Achille Sclavo's (1861-1930) message for Italian schools 100 years after the publication of his book "The Propagation of Hygiene". Achille Sclavo(1861-1930 年)的著作《卫生宣传》出版 100 年后,他对意大利学校的现代启示。
Pub Date : 2024-08-31 eCollection Date: 2024-06-01 DOI: 10.15167/2421-4248/jpmh2024.65.2.3312
Davide Orsini, Maria Luisa Cristina, Masoud Behzadifar, Mariano Martini

A hundred years ago, Achille Sclavo (1861-1930) published his book entitled "Per la Propaganda igienica. Scuola e Igiene" (The Propagation of Hygiene. Schools and Hygiene) which he dedicated "To elementary teachers, from whom Italy expects the most effective propaganda in favor of hygiene". The words of the dedication were profoundly felt by Sclavo and reveal a precise choice by the great hygienist. Sclavo was then at an advanced age and had devoted his whole life to studying hygiene and disseminating its basic concepts, to promote a healthier life for all. Nowadays, Sclavo's book "The Propagation of Hygiene. Schools and Hygiene" still remains an important statement to the commitment of the great hygienist to spreading a culture of hygiene, and public health in Italy. This was a commitment that Sclavo clearly felt throughout his life, as a teacher, as a scholar, as the entrepreneur who founded the Serotherapy and Vaccinogenic Institute in 1904, and mainly as a policymaker who spoke to all citizens, especially young people.

一百年前,阿奇勒-斯克拉沃(1861-1930 年)出版了题为《卫生宣传:学校与卫生》(Per la Propaganda igienica.Scuola e Igiene"(《卫生宣传:学校与卫生》)一书,他将此书献给了 "小学教师,意大利期望从他们那里得到最有效的卫生宣传"。斯克拉沃对献词中的这句话深有感触,它揭示了这位伟大卫生学家的准确选择。斯克拉沃当时已年逾古稀,毕生致力于研究卫生学和传播卫生学的基本概念,以促进所有人过上更健康的生活。如今,斯克拉沃的著作《卫生的传播。学校与卫生》一书仍然是这位伟大的卫生学家致力于在意大利传播卫生文化和公共卫生的重要宣言。作为一名教师、学者、1904 年创办血清疗法和疫苗研究所的企业家,以及主要是作为一名与所有公民,尤其是年轻人对话的政策制定者,斯克拉沃一生都清楚地感受到这一承诺。
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引用次数: 0
First real-world data on universal respiratory syncytial virus prophylaxis with Nirsevimab in infants. 关于婴儿使用 Nirsevimab 普遍预防呼吸道合胞病毒的首个真实世界数据。
Pub Date : 2024-08-31 eCollection Date: 2024-06-01 DOI: 10.15167/2421-4248/jpmh2024.65.2.3329
Andrea Orsi, Marianna Scarpaleggia, Vincenzo Baldo, Fabio Barbone, Maria Chironna, Sandro Giuffrida, Emanuele Montomoli, Elena Pariani, Caterina Rizzo, Donatella Panatto, Giancarlo Icardi

Introduction: Respiratory Syncytial Virus (RSV) predominantly affects young children, with a peak incidence in temperate regions of the northern hemisphere from October to May. Children under 24 months of age are particularly vulnerable because of the immaturity of their lungs and immune systems, often leading to severe respiratory infections. The World Health Organization (WHO) recognizes RSV as a global health priority. Recently, Nirsevimab, a long-acting monoclonal antibody (mAb), was authorised to prevent RSV disease in infants.

Methods: Our narrative review brings together the effectiveness data of Nirsevimab available in the literature, highlighting the strengths and weaknesses of the published studies and the prevention opportunities represented by the new preparation.

Results: All reviewed studies provide evidence for the effectiveness of immunisation with Nirsevimab in real-world settings, beyond the controlled conditions of clinical trials, and highlight its safety and feasibility. Nirsevimab significantly reduces RSV hospitalisations and Intensive Care Unit (ICU) admissions. High coverage and high efficacy of immunisation have been reported, although supply issues and variability in studies present challenges.

Conclusions: Continued research and surveillance are critical to understanding the long-term effectiveness of Nirsevimab. Overall, available data provide valuable insights into the efficacy, safety, and impact of immunisation with Nirsevimab in preventing severe RSV infections in infants, highlighting its potential to reduce the burden of RSV-related hospitalisations and improve paediatric health outcomes.

导言:呼吸道合胞病毒(RSV)主要影响幼儿,北半球温带地区的发病高峰期为 10 月至 5 月。24 个月以下的儿童由于肺部和免疫系统尚未发育成熟,特别容易受到感染,往往会导致严重的呼吸道感染。世界卫生组织(WHO)将 RSV 视为全球健康的优先事项。最近,长效单克隆抗体(mAb)Nirsevimab获准用于预防婴儿RSV疾病:我们的叙述性综述汇集了文献中关于 Nirsevimab 的有效性数据,强调了已发表研究的优缺点以及新制剂所代表的预防机会:结果:所有综述研究都证明了在实际环境中使用 Nirsevimab 进行免疫接种的有效性,超越了临床试验的受控条件,并强调了其安全性和可行性。Nirsevimab大大减少了RSV住院率和重症监护室(ICU)入院率。尽管供应问题和研究的不一致性带来了挑战,但免疫接种的高覆盖率和高效率已得到报道:持续的研究和监测对于了解 Nirsevimab 的长期有效性至关重要。总之,现有数据为了解使用 Nirsevimab 免疫接种在预防婴儿严重 RSV 感染方面的有效性、安全性和影响提供了宝贵的信息,凸显了 Nirsevimab 在减少 RSV 相关住院负担和改善儿科健康状况方面的潜力。
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引用次数: 0
University students in Central Italy: do they follow proper dietary habits? 意大利中部的大学生:他们是否有正确的饮食习惯?
Pub Date : 2024-08-31 eCollection Date: 2024-06-01 DOI: 10.15167/2421-4248/jpmh2024.65.2.3194
Vigiani Nicola, Quercioli Cecilia, Fanti Elisa, Frilli Eleonora, Messina Gabriele, Nicola Nante

Background: Eating a healthy diet is acknowledged as one of the main factors in preventing malnutrition and non-communicable diseases. As young students represent a group more prone to poor dietary habits, the aim of this study was to analyse the dietary habits of a group of undergraduate students attending university in a city of central Italy, Siena.

Methods: 4,700 students were invited to participate in a cross-sectional study completing an online self-administered questionnaire about their food habits. The obtained data were analysed by Microsoft Excel 2021 and Stata 17 software, through the Mann-Whitney and the Kruskal-Wallis test; a p-value < 0.05 was considered statistically significant.

Results: The students living at home consumed more fruit, vegetables, pasta, meat, fish, packaged foods, fruit juices, beer and wine; the only statistically significant differences were found for pizza and snacks. Even the gender influenced the consumption of many foods; women consumed more vegetables and coffee/tea, while males ate more pasta, meat, packaged foods, pizza, fries and beer.

Conclusions: With the transition from secondary school to university, students are continuously challenged to make healthful food choices and they must be self-disciplined to take care of themselves. It would be important for health campaigns to be promoted in young adults to help them make the right choices.

背景:健康饮食被认为是预防营养不良和非传染性疾病的主要因素之一。由于青年学生是一个更容易养成不良饮食习惯的群体,本研究旨在分析意大利中部城市锡耶纳的一群大学本科生的饮食习惯。方法:本研究邀请了 4,700 名学生参与一项横断面研究,他们在网上填写了一份有关饮食习惯的自填问卷。获得的数据由 Microsoft Excel 2021 和 Stata 17 软件通过 Mann-Whitney 和 Kruskal-Wallis 检验进行分析;P 值小于 0.05 视为具有统计学意义:结果:住在家里的学生消费了更多的水果、蔬菜、面食、肉类、鱼类、包装食品、果汁、啤酒和葡萄酒;唯一在统计上有显著差异的是披萨和零食。性别甚至影响了许多食物的消费;女性消费更多的蔬菜和咖啡/茶,而男性则消费更多的面食、肉类、包装食品、披萨、薯条和啤酒:随着从中学到大学的过渡,学生们不断面临着选择健康食品的挑战,他们必须自律,照顾好自己。在青壮年中推广健康运动,帮助他们做出正确的选择非常重要。
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引用次数: 0
How the Anthropocene is changing bioethics. 人类世如何改变生物伦理学。
Pub Date : 2024-08-31 eCollection Date: 2024-06-01 DOI: 10.15167/2421-4248/jpmh2024.65.2.3224
Paolo Donadoni, Rosagemma Ciliberti

The complex challenges of the Anthropocene imply a careful reconsideration of the ethical boundaries of human morality and a heightened sensitivity to the interconnectedness among all living beings. This means that bioethics, traditionally anchored in interhuman relations within the healthcare domain, is called upon to broaden the scope of its operational horizon, encompassing issues related to interspecific relations, environmental health, sustainability, equitable distribution of natural resources, and responsibility for environmental damages. This article explores the intersection between the anthropocentric era and the ethical challenges arising from our increasing influence on the environment and other life forms with which we share the planet. The teaching of fundamental ethical concepts such as solidarity, social responsibility, and equity becomes crucial for nurturing informed and responsible citizens. In doing so, not only is greater awareness promoted regarding global challenges related to health and the environment, but critical skills are also developed to address them proactively.

人类世所面临的复杂挑战要求我们认真重新考虑人类道德的伦理界限,提高对所有生 物之间相互联系的敏感性。这意味着,传统上立足于医疗保健领域人与人之间关系的生命伦理学,需要拓宽其业务范围,涵盖与物种间关系、环境健康、可持续性、自然资源的公平分配以及环境损害责任相关的问题。本文探讨了人类中心主义时代与我们对环境和与我们共同生活在这个星球上的其他生命形式日益增长的影响所带来的伦理挑战之间的交集。讲授团结、社会责任和公平等基本伦理概念对于培养知情和负责任的公民至关重要。这样做不仅可以提高人们对健康和环境方面的全球挑战的认识,还可以培养积极应对这些挑战的关键技能。
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引用次数: 0
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Journal of preventive medicine and hygiene
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