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Healthcare infections and antimicrobial consumption in pre-COVID-19 era: a point prevalence survey in three hospitals in a region of Central Italy. 前 COVID-19 时代的医疗感染和抗菌药消耗:意大利中部地区三家医院的点流行率调查。
Pub Date : 2024-01-01 eCollection Date: 2023-12-01 DOI: 10.15167/2421-4248/jpmh2023.64.4.2962
Manuela Tamburro, Angelo Salzo, Michela Lucia Sammarco, Giancarlo Ripabelli

Introduction: Healthcare-associated infections (HAIs) are a major global public health concern, increasing the transmission of drug-resistant infections. This point prevalence survey investigated HAIs occurrence and antimicrobial consumption (AMC) in pre-COVID-19 era in the public hospitals of a region of Central Italy.

Methods: Data were collected using the protocol standardised by the European Centre for Disease Prevention and Control.

Results: Three-hundred and sixty-four patients were included (59.3% male) in the study. Overall, HAIs prevalence was 6.6% (95%CI 4.4-9.5), ranging from 5.2% to 7.1% within the surveyed hospitals, with at least one infection in 24 patients (ten each in medical and surgical specialties wards, and four in intensive care). Risk factors for HAIs were advanced age, having undergone surgery and wearing invasive devices. At time of the survey, 44.7% (95%CI 39.7-49.9) of patients was under treatment with at least one antibiotic, and AMC varied between 43% and 48% within hospitals. In all hospitals, a prevalence higher than 10% was found for the prescription reasons other than prophylaxis or therapy.

Conclusions: The results revealed a HAIs prevalence lower than that estimated compared to the most recent national data, in contrast to higher antimicrobial usage. These findings highlight the need to reinforce hygiene practices and develop bundles for HAIs, as a broad implementation of infection prevention and control practices extensively applied to both hub and spoke hospitals could significantly reduce their occurrence, as well as to implement antimicrobial stewardship for prescriptive appropriateness.

导言:医疗相关感染(HAIs)是全球公共卫生关注的一个主要问题,它增加了耐药性感染的传播。这项点流行率调查研究了意大利中部一个地区的公立医院在前 COVID-19 时代的 HAIs 发生率和抗菌药物消耗量(AMC):方法:采用欧洲疾病预防与控制中心(European Centre for Disease Prevention and Control)的标准化方案收集数据:研究共纳入了 364 名患者(59.3% 为男性)。总体而言,HAIs 感染率为 6.6%(95%CI 4.4-9.5),调查医院内的感染率从 5.2% 到 7.1% 不等,24 名患者(内科和外科专科病房各 10 名,重症监护病房 4 名)中至少有一人感染。高龄、接受过手术和佩戴侵入性设备是导致 HAIs 的风险因素。在调查期间,44.7%(95%CI 39.7-49.9)的患者正在接受至少一种抗生素的治疗,各医院的 AMC 在 43% 和 48% 之间。在所有医院中,除预防或治疗外,其他处方的使用率均高于 10%:结果显示,与最新的全国数据相比,HAIs 的流行率低于估计值,而抗菌药物的使用率却较高。这些研究结果突出表明,有必要加强卫生习惯并制定针对 HAIs 的捆绑措施,因为在枢纽医院和辐条医院广泛实施感染预防和控制措施,可以显著减少 HAIs 的发生,并实施抗菌药物管理以确保处方的适当性。
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引用次数: 0
Psychotherapy, artificial intelligence and adolescents: ethical aspects. 心理治疗、人工智能和青少年:伦理问题。
Pub Date : 2024-01-01 eCollection Date: 2023-12-01 DOI: 10.15167/2421-4248/jpmh2023.64.4.3135
Linda Alfano, Ivano Malcotti, Rosagemma Ciliberti

Artificial intelligence (AI) has rapidly advanced in various domains, including its application in psychotherapy. AI-powered psychotherapy tools present promising solutions for increasing accessibility to mental health care. However, the integration of AI in psychotherapy raises significant ethical concerns that require thorough consideration and regulation to ensure ethical practice, patient safety, and data privacy. This article discusses the ethical considerations surrounding the utilization of AI in psychotherapy, emphasizing the need for responsible implementation, patient privacy, and the human-AI interaction. The challenge raised by the use of artificial intelligence requires a comprehensive approach. Schools, in particular, are crucial in providing both knowledge and ethical guidance, helping young individuals decipher the complexities of online content. Additionally, parental support is essential, requiring the provision of time, fostering relationships, encouraging dialogue, and creating a safe environment to share experiences amidst the intricacies of adolescence. Reimagining social and healthcare services tailored for adolescents is equally crucial, taking into account recent societal changes. The integration of AI in psychotherapy has vast potential to transform mental healthcare. However, ensuring its accuracy and effectiveness demands a proactive approach to address associated ethical considerations. By adopting responsible practices, preserving patient autonomy, and continually refining AI systems, the field can leverage the benefits of AI in psychotherapy while maintaining high ethical standards.

人工智能(AI)在各个领域都取得了飞速发展,包括在心理治疗中的应用。人工智能驱动的心理治疗工具为提高心理健康护理的可及性提供了前景广阔的解决方案。然而,将人工智能整合到心理治疗中会引发重大的伦理问题,需要进行全面的考虑和监管,以确保道德实践、患者安全和数据隐私。本文讨论了在心理治疗中使用人工智能的伦理问题,强调了负责任的实施、患者隐私以及人与人工智能互动的必要性。人工智能的使用所带来的挑战需要一种全面的方法。学校在提供知识和道德指导方面尤为重要,可以帮助年轻人解读复杂的网络内容。此外,家长的支持也至关重要,这需要提供时间、促进关系、鼓励对话,并创造一个安全的环境,以便在错综复杂的青春期中分享经验。考虑到最近的社会变化,重新设计为青少年量身定制的社会和医疗保健服务同样至关重要。将人工智能融入心理治疗,在改变心理医疗保健方面有着巨大的潜力。然而,要确保其准确性和有效性,就必须采取积极主动的方法来解决相关的伦理问题。通过采取负责任的做法、维护患者自主权并不断完善人工智能系统,该领域可以在保持高道德标准的同时,充分利用人工智能在心理治疗中的优势。
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引用次数: 0
Feasibility study on a new enhanced device for patients with intermittent catheterization (LUJA). 针对间歇性导尿患者的新型增强装置(LUJA)的可行性研究。
Pub Date : 2023-11-20 eCollection Date: 2023-09-01 DOI: 10.15167/2421-4248/jpmh2023.64.3s1
Giovanna Elisa Calabrò, Floriana D'Ambrosio, Francesca Orsini, Ciro Pappalardo, Anna Scardigno, Filippo Rumi, Alessandra Fiore, Roberto Ricciardi, Americo Cicchetti
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引用次数: 0
History of primary health care in Iran. 伊朗初级卫生保健的历史。
Pub Date : 2023-11-01 eCollection Date: 2023-09-01 DOI: 10.15167/2421-4248/jpmh2023.64.3.3081
Ali Aboutorabi, Banafshe Darvishi Teli, Aziz Rezapour, Seyed Jafar Ehsanzadeh, Mariano Martini, Masoud Behzadifar

Background: The history of the primary healthcare system in Iran portrays a journey of strategic development and implementation that has resulted in significant advancements in healthcare access and overall population well-being. Starting in the early 1980s, Iran embarked on a comprehensive approach to health care delivery prioritizing universal access, equity, and community participation.

Introduction: The foundation of this system was established during the Alma-Ata Conference in 1978, which placed a strong emphasis on the role of primary health care in attaining health for all.Iran's unwavering commitment to this approach led to the creation of an extensive network of rural and urban health centers designed to offer essential health services and preventive care to all citizens.

Discussion: Over the years, the expansion of Iran's primary healthcare system has yielded noteworthy accomplishments. Maternal and child mortality rates have seen substantial declines, attributed to improved access to maternal care and immunization services. The effectiveness of the system in reaching diverse populations has been enhanced through community engagement and the integration of traditional medicine. Furthermore, Iran's focus on health education and disease prevention has resulted in heightened public awareness and the adoption of healthier lifestyles. Despite these achievements, challenges continue to persist. Disparities in the quality and accessibility of services between urban and rural areas remain a concern. Moreover, the ongoing necessity for infrastructure development, training of the health workforce, and efficient resource allocation underscore the continuous efforts required to strengthen the primary healthcare system.

Conclusions: The history of Iran's primary health care system is marked by progress and achievements, underscored by an unwavering commitment to providing comprehensive, community-based care. Iran's journey serves as an exemplary model, highlighting the positive impact of prioritizing primary health care in achieving better health outcomes for its population. As Iran continues to evolve its health system, addressing challenges and building upon successes, the history of its primary health care system serves as a valuable lesson in the pursuit of accessible and equitable health care for all.

背景:伊朗初级医疗保健系统的发展史描绘了一个战略发展和实施的历程,其结果是在医疗保健的获取和整体人口福祉方面取得了重大进展。从 20 世纪 80 年代初开始,伊朗开始采用一种全面的方法来提供医疗保健服务,优先考虑普及、公平和社区参与:1978 年阿拉木图会议确立了这一体系的基础,会议着重强调了初级医疗保健在实现全民健康中的作用。伊朗坚定不移地致力于这一方法,建立了广泛的农村和城市医疗中心网络,旨在为所有公民提供基本的医疗服务和预防保健:多年来,伊朗初级保健系统的扩展取得了显著成就。孕产妇和儿童死亡率大幅下降,这要归功于孕产妇保健和免疫接种服务的改善。通过社区参与和整合传统医学,该系统在覆盖不同人群方面的有效性得到了提高。此外,伊朗对健康教育和疾病预防的重视提高了公众的认识,并使他们采用了更健康的生活方式。尽管取得了这些成就,但挑战依然存在。城市和农村地区在服务质量和可及性方面的差距仍然令人担忧。此外,不断发展基础设施、培训卫生工作者队伍和有效分配资源的必要性也凸显了加强初级卫生保健系统所需的持续努力:伊朗初级卫生保健系统的历史充满了进步和成就,其突出特点是坚定不移地致力于提供全面的、以社区为基础的医疗保健服务。伊朗的发展历程堪称典范,彰显了优先发展初级医疗保健对提高人民健康水平的积极影响。随着伊朗继续发展其卫生系统,应对挑战并在成功的基础上再接再厉,其初级卫生保健系统的历史将成为追求人人享有可及和公平的卫生保健的宝贵经验。
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引用次数: 0
Integrating one health: exploring the global dialogue on bioethics. 整合一种健康:探索全球生物伦理对话。
Pub Date : 2023-11-01 eCollection Date: 2023-09-01 DOI: 10.15167/2421-4248/jpmh2023.64.3.3021
Rosagemma Ciliberti, Valeria Schiavone

Unesco's World Bioethics Day, whose theme this year is the protection of future generations, reveals the centrality of the concept of one-health, as the main way to guarantee a future for the planet seen as the common home of all living beings. The recent pandemic has sufficiently shown how animal health is linked to human health and how only the balance of the entire planet guarantees both. Living on earth as human beings, no longer blinded by the Anthropocene's arrogance, but conscious of having a fundamental responsibility for the health care and well-being of every species is the imperative that should guide scientific research, education and social life. Thus, a renovating of the education system is essential to break down rigid boundaries between disciplines and promote complex and critical thinking.

联合国教科文组织 "世界生物伦理日 "今年的主题是 "保护子孙后代",它揭示了 "一体健康 "概念的核心地位,因为它是保障被视为所有生物共同家园的地球未来的主要途径。最近的疫情充分表明,动物健康与人类健康息息相关,只有整个地球的平衡才能保证两者的健康。作为人类生活在地球上,不再被 "人类世 "的傲慢所蒙蔽,而是意识到对每个物种的健康和福祉负有根本责任,这是指导科学研究、教育和社会生活的当务之急。因此,必须革新教育系统,打破学科之间僵化的界限,促进复杂的批判性思维。
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引用次数: 0
Addressing childhood obesity through policy: A cross-sectional study in Malta. 通过政策解决儿童肥胖问题:马耳他横断面研究。
Pub Date : 2023-11-01 eCollection Date: 2023-09-01 DOI: 10.15167/2421-4248/jpmh2023.64.3.2938
Marika Borg, Daniel Cauchi, Charmaine Gauci, Neville Calleja

Introduction: Childhood overweight and obesity are major public health challenges, with Malta having one of the highest prevalences among European countries. The COVID-19 pandemic may further worsen this epidemic. The food and physical activity environments impact children's behaviours. This study looks at barriers to maintain a healthy weight, responsibility to address obesity, and assesses parental support for 22 policies aimed at addressing childhood obesity. Public support for policy is key because it influences which policies are adopted and their success.

Methods: A cross-sectional, paper-based, quantitative survey was conducted amongst parents of primary school-aged children in Malta in 2018-2019. Ethical approval was obtained. Statistical analysis was performed using SPSS.

Results: 1,169 parents participated. The food environment was more commonly identified as a barrier to maintain a healthy weight than the physical activity environment. Parents were least supportive of taxation policies, and most in favour of increasing spaces available for safe physical activity (94.0%), followed by providing free weight management services for children (90.8%). The level of support varied significantly by various socio-demographic/economic characteristics; parents with a higher educational level were significantly more supportive of most policies. Most findings were consistent with the international literature.

Conclusions: Most policies supported are trans-sectoral; a health-in-all policies approach is needed to address the obesogenic environment. The strong public support identified for several policies should embolden policymakers to consider policy options that were not previously considered.

导言:儿童超重和肥胖是主要的公共卫生挑战,马耳他是欧洲国家中发病率最高的国家之一。COVID-19 的流行可能会使这一流行病进一步恶化。食品和体育活动环境会影响儿童的行为。本研究探讨了保持健康体重的障碍、解决肥胖问题的责任,并评估了家长对 22 项旨在解决儿童肥胖问题的政策的支持情况。公众对政策的支持是关键,因为它影响着政策的采用及其成功与否:2018-2019 年,在马耳他小学学龄儿童的家长中开展了一项横断面纸质定量调查。已获得伦理批准。使用 SPSS 进行统计分析:1169名家长参与了调查。与体育锻炼环境相比,食品环境更常被认为是保持健康体重的障碍。家长对税收政策的支持率最低,而对增加安全体育活动空间的支持率最高(94.0%),其次是为儿童提供免费体重管理服务(90.8%)。不同社会-人口/经济特征的家长对政策的支持程度差异很大;教育程度较高的家长对大多数政策的支持程度明显更高。大多数调查结果与国际文献一致:结论:大多数获得支持的政策都是跨部门的;需要采取将健康纳入所有政策的方法来应对导致肥胖的环境。公众对几项政策的大力支持应鼓励政策制定者考虑以前未曾考虑过的政策方案。
{"title":"Addressing childhood obesity through policy: A cross-sectional study in Malta.","authors":"Marika Borg, Daniel Cauchi, Charmaine Gauci, Neville Calleja","doi":"10.15167/2421-4248/jpmh2023.64.3.2938","DOIUrl":"https://doi.org/10.15167/2421-4248/jpmh2023.64.3.2938","url":null,"abstract":"<p><strong>Introduction: </strong>Childhood overweight and obesity are major public health challenges, with Malta having one of the highest prevalences among European countries. The COVID-19 pandemic may further worsen this epidemic. The food and physical activity environments impact children's behaviours. This study looks at barriers to maintain a healthy weight, responsibility to address obesity, and assesses parental support for 22 policies aimed at addressing childhood obesity. Public support for policy is key because it influences which policies are adopted and their success.</p><p><strong>Methods: </strong>A cross-sectional, paper-based, quantitative survey was conducted amongst parents of primary school-aged children in Malta in 2018-2019. Ethical approval was obtained. Statistical analysis was performed using SPSS.</p><p><strong>Results: </strong>1,169 parents participated. The food environment was more commonly identified as a barrier to maintain a healthy weight than the physical activity environment. Parents were least supportive of taxation policies, and most in favour of increasing spaces available for safe physical activity (94.0%), followed by providing free weight management services for children (90.8%). The level of support varied significantly by various socio-demographic/economic characteristics; parents with a higher educational level were significantly more supportive of most policies. Most findings were consistent with the international literature.</p><p><strong>Conclusions: </strong>Most policies supported are trans-sectoral; a health-in-all policies approach is needed to address the obesogenic environment. The strong public support identified for several policies should embolden policymakers to consider policy options that were not previously considered.</p>","PeriodicalId":94106,"journal":{"name":"Journal of preventive medicine and hygiene","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10730052/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138833752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding conflicts of interest in rational drug prescription in a developing country: A stakeholder analysis, healthcare guidelines and ethical public health issues. 了解发展中国家合理用药中的利益冲突:利益相关者分析、医疗保健指南和公共卫生伦理问题。
Pub Date : 2023-11-01 eCollection Date: 2023-09-01 DOI: 10.15167/2421-4248/jpmh2023.64.3.3036
Farideh Moradi, Mohammad Bazyar, Ali Soroush, Hesam Seyedin, Fatemeh Soleymani, Manal Etemadi, Saeed Ezadi, Mehdi Salimi, Masoud Behzadifar, Mariano Martini, Rezwana Hussain

Background: Rational drug prescription (RDP) is one of the main components of the healthcare systems. Irrational prescribing can bring about numerous negative consequences for the patients and governmental agencies. This study aims to analyze the involvement of stakeholders in rational drug prescribing, their position (opponent or proponent), and the rationale behind it.

Methods: This was a qualitative study conducted in 2019. Semi-structured face-to-face interviews were conducted with 40 stakeholders. Purposive and snowball sampling techniques with maximum heterogeneity were adopted to select the interviewees. Data was analyzed by MAXQDA software using thematic approach.

Results: Iranian Food and Drug Administration employs the highest authority on the rational prescribing policy. Although the Ministry of Health and Medical Education, the Social Security Organization as one of the main health insurance organizations, pharmaceutical companies, and the Medical Council of the Islamic Republic of Iran, are among agencies that have great authority to improve rational prescribing, they fail to act professionally as they have conflicting interests. Remarkably, the Iran Food and Drug Administration, insurance organizations, family physicians, and patients, highly support the rational prescribing policy while the pharmaceutical companies display the least support for it.

Conclusions: To make the prescription and using drugs more rational, policy makers should focus on different sources of conflicts of interest that different actors have. They should devise legal, behavior and financial policies accordingly to lessen or at least neutralize these conflicting interests, otherwise achieving RDP would be impossible in short and long terms.

背景:合理用药处方(RDP)是医疗保健系统的主要组成部分之一。不合理处方会给患者和政府机构带来许多负面影响。本研究旨在分析利益相关者参与合理用药的情况、他们的立场(反对者或支持者)及其背后的理由:这是一项于 2019 年开展的定性研究。对 40 名利益相关者进行了半结构化面对面访谈。在选择受访者时,采用了具有最大异质性的有目的抽样和滚雪球抽样技术。采用 MAXQDA 软件对数据进行了专题分析:伊朗食品药品管理局是合理用药政策的最高权力机构。虽然卫生和医学教育部、作为主要医疗保险组织之一的社会保障组织、制药公司和伊朗伊斯兰共和国医学委员会等机构在改善合理用药方面拥有很大的权力,但由于它们之间存在利益冲突,因此未能采取专业的行动。值得注意的是,伊朗食品药品管理局、保险组织、家庭医生和患者都非常支持合理处方政策,而制药公司对该政策的支持度最低:为使处方和用药更加合理,政策制定者应关注不同参与者的不同利益冲突来源。结论:为使处方和用药更加合理,政策制定者应关注不同参与者的不同利益冲突来源,并制定相应的法律、行为和财政政策,以减少或至少中和这些利益冲突,否则,从短期和长期来看,实现合理用药都是不可能的。
{"title":"Understanding conflicts of interest in rational drug prescription in a developing country: A stakeholder analysis, healthcare guidelines and ethical public health issues.","authors":"Farideh Moradi, Mohammad Bazyar, Ali Soroush, Hesam Seyedin, Fatemeh Soleymani, Manal Etemadi, Saeed Ezadi, Mehdi Salimi, Masoud Behzadifar, Mariano Martini, Rezwana Hussain","doi":"10.15167/2421-4248/jpmh2023.64.3.3036","DOIUrl":"https://doi.org/10.15167/2421-4248/jpmh2023.64.3.3036","url":null,"abstract":"<p><strong>Background: </strong>Rational drug prescription (RDP) is one of the main components of the healthcare systems. Irrational prescribing can bring about numerous negative consequences for the patients and governmental agencies. This study aims to analyze the involvement of stakeholders in rational drug prescribing, their position (opponent or proponent), and the rationale behind it.</p><p><strong>Methods: </strong>This was a qualitative study conducted in 2019. Semi-structured face-to-face interviews were conducted with 40 stakeholders. Purposive and snowball sampling techniques with maximum heterogeneity were adopted to select the interviewees. Data was analyzed by MAXQDA software using thematic approach.</p><p><strong>Results: </strong>Iranian Food and Drug Administration employs the highest authority on the rational prescribing policy. Although the Ministry of Health and Medical Education, the Social Security Organization as one of the main health insurance organizations, pharmaceutical companies, and the Medical Council of the Islamic Republic of Iran, are among agencies that have great authority to improve rational prescribing, they fail to act professionally as they have conflicting interests. Remarkably, the Iran Food and Drug Administration, insurance organizations, family physicians, and patients, highly support the rational prescribing policy while the pharmaceutical companies display the least support for it.</p><p><strong>Conclusions: </strong>To make the prescription and using drugs more rational, policy makers should focus on different sources of conflicts of interest that different actors have. They should devise legal, behavior and financial policies accordingly to lessen or at least neutralize these conflicting interests, otherwise achieving RDP would be impossible in short and long terms.</p>","PeriodicalId":94106,"journal":{"name":"Journal of preventive medicine and hygiene","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10730053/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138833710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of death risk factors among COVID-19 patients in Yazd, Iran: A case-cohort study. 伊朗亚兹德 COVID-19 患者死亡风险因素分析:病例队列研究。
Pub Date : 2023-11-01 eCollection Date: 2023-09-01 DOI: 10.15167/2421-4248/jpmh2023.64.3.3098
Mohammadreza Mirjalili, Mehdi Raadabadi, Mohammadreza Dehghani, Mohammad Bakhtiari Aliabad, Mehrdad Mansouri, Mariano Martini, Ali Dehghani

Background: The COVID-19 epidemic control has become a global challenge and many contributing variables are still unknown to policymakers. This case-cohort study was conducted to investigate the risk factors of mortality in COVID-19 patients.

Methods: This case-cohort study was conducted on 956 samples in Ardakan and Meybod counties, Yazd Province, between February 20 and May 20, 2020. The data collection tool was a researcher-made questionnaire. Data analysis was done using descriptive statistics and paired t-test, chi-square, and logistic regression analysis.

Results: Of a total cohort population of 993 in Ardakan and Meybod counties, 435 were assigned to the control group and 521 were assigned to the case group. The results of outcome analysis showed that 14.4% of the patients in the case group and 11.5% of the patients in the control group died. According to the results of logistic regression analysis in COVID-19 patients, each one-year increase in age increased the risk of mortality by 6% (HR = 1.06, p < 0.001), each one-day increase in the hospital stay increased the risk of death by 8% (HR = 1.08, p < 0.001). Moreover, the presence of cardiovascular disease, chronic neurological disease, and chronic pulmonary disease increased the risk of death. The patients who underwent mechanical ventilation had 85% less chance of survival (HR = 0.15, p < 0.001).

Conclusions: The results showed a higher mortality rate in the elderly patients as well as those with underlying diseases. Attention should be paid to at-risk and elderly patients in terms of ensuring a healthy diet, improving their self-care practices, and providing long-term medical and healthcare facilities.

背景:COVID-19疫情的控制已成为一项全球性挑战,而决策者对许多诱发因素仍一无所知。本病例队列研究旨在调查 COVID-19 患者死亡的风险因素:这项病例队列研究在 2020 年 2 月 20 日至 5 月 20 日期间对亚兹德省阿尔达坎县和梅博德县的 956 个样本进行了调查。数据收集工具为研究人员自制的调查问卷。数据分析采用描述性统计、配对 t 检验、卡方检验和逻辑回归分析:在阿尔达坎县和迈博德县的 993 名队列人口中,435 人被分配到对照组,521 人被分配到病例组。结果分析表明,病例组和对照组分别有 14.4% 和 11.5% 的患者死亡。根据 COVID-19 患者的逻辑回归分析结果,年龄每增加一年,死亡风险增加 6%(HR = 1.06,P < 0.001),住院时间每增加一天,死亡风险增加 8%(HR = 1.08,P < 0.001)。此外,心血管疾病、慢性神经系统疾病和慢性肺部疾病也会增加死亡风险。接受机械通气的患者存活几率降低了85%(HR = 0.15,P < 0.001):结果显示,老年患者和患有基础疾病的患者死亡率较高。结论:结果显示,老年患者以及患有基础疾病的患者的死亡率较高,因此应关注高危患者和老年患者,确保其饮食健康,改善其自我护理方法,并提供长期的医疗和保健设施。
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引用次数: 0
Effectiveness of a vaccine recovery plan after the COVID-19 pandemic in the Siracusa Local Health Authority, Italy. Results of one year follow-up. 意大利锡拉库萨地方卫生局 COVID-19 大流行后疫苗恢复计划的有效性。一年跟踪结果。
Pub Date : 2023-11-01 eCollection Date: 2023-09-01 DOI: 10.15167/2421-4248/jpmh2023.64.3.3001
Fabio Contarino, Erminio DI Pietro, Concetta Randazzo, Francesca Bella, Maria Lia Contrino

Introduction: The COVID-19 pandemic has strongly impacted on the immunization services around the world, threatening the gains made in the control of vaccine-preventable diseases.

Methods: A vaccination recovery plan of missed vaccinations has been put in place in the LHA of Siracusa after the pandemic. We compared 2021 and 2020 vaccination coverage by age group and vaccine type after one year of follow-up of the recovery plan. The Chi-square test was executed on proportions for the years 2021 vs 2020. Results were considered statistically significant at a two-tailed p-value ≤ 0.05.

Results: 36-month coverage rates were 92.5% for polio and 93.7% for measles-containing-vaccine, representing -0.3% and -1.8% decreases, respectively, as compared to 2020. By 8 years of age (booster doses), immunisation coverage was 80.7% for polio and 80.1% for measles, representing a -5.7% and -3.7%, respectively, compared to 2020. 36-month coverage was 56.6% for Men B (-5.0% as compared to 2020), 73.2% for Men ACW135Y/C (+1.1% as compared to 2020) and 86.9% for PNC vaccine (-1.7%, as compared to 2020). Regarding HPV vaccination, in 2021, vaccine coverage was 44.2% (-4.4% compared to 2020). Compared to the previous report, the VC difference among the cohorts narrowed for all almost vaccinations, except for the anti-men B and the anti-HPV vaccination, for which we recorded an increase in VC difference, and for men ACW135Y/C, for which a significant increase has been recorded.

Conclusions: Despite the efforts to organize and realize an extensive and well-designed vaccination recovery, our data show that even after the 1-year follow-up, globally deficits in coverage for these routine vaccinations persist, although there has been a substantial and significant recovery of missed vaccinations, especially among younger children and for primary cycles.

导言:COVID-19 大流行对世界各地的免疫接种服务造成了严重影响,威胁到在控制疫苗可预防疾病方面取得的成果:方法:大流行后,锡拉库扎地方卫生局制定了一项疫苗接种恢复计划,对漏种疫苗进行补种。我们比较了恢复计划实施一年后按年龄组和疫苗类型划分的 2021 年和 2020 年疫苗接种覆盖率。我们对 2021 年与 2020 年的比例进行了卡方检验。在双尾 p 值≤ 0.05 时,结果具有统计学意义:与 2020 年相比,小儿麻痹症和含麻疹成分疫苗的 36 个月覆盖率分别为 92.5%和 93.7%,分别下降了-0.3%和-1.8%。到 8 岁(加强剂量)时,小儿麻痹症的免疫接种率为 80.7%,麻疹的免疫接种率为 80.1%,与 2020 年相比分别下降了-5.7%和-3.7%。36 个月的接种率分别为:男乙疫苗 56.6%(与 2020 年相比-5.0%),男 ACW135Y/C 疫苗 73.2%(与 2020 年相比+1.1%),PNC 疫苗 86.9%(与 2020 年相比-1.7%)。2021 年,HPV 疫苗接种覆盖率为 44.2%(与 2020 年相比为-4.4%)。与上一份报告相比,除抗男性乙型肝炎疫苗和抗人类乳头瘤病毒疫苗接种的VC差异有所扩大,以及男性ACW135Y/C疫苗接种的VC差异显著扩大外,几乎所有疫苗接种的VC差异都有所缩小:尽管努力组织并实现了广泛而精心设计的疫苗接种恢复工作,但我们的数据显示,即使在 1 年的随访之后,这些常规疫苗接种的覆盖率仍然存在全球性的不足,尽管错过接种的疫苗接种率有了实质性的显著恢复,尤其是在年龄较小的儿童和初免周期中。
{"title":"Effectiveness of a vaccine recovery plan after the COVID-19 pandemic in the Siracusa Local Health Authority, Italy. Results of one year follow-up.","authors":"Fabio Contarino, Erminio DI Pietro, Concetta Randazzo, Francesca Bella, Maria Lia Contrino","doi":"10.15167/2421-4248/jpmh2023.64.3.3001","DOIUrl":"https://doi.org/10.15167/2421-4248/jpmh2023.64.3.3001","url":null,"abstract":"<p><strong>Introduction: </strong>The COVID-19 pandemic has strongly impacted on the immunization services around the world, threatening the gains made in the control of vaccine-preventable diseases.</p><p><strong>Methods: </strong>A vaccination recovery plan of missed vaccinations has been put in place in the LHA of Siracusa after the pandemic. We compared 2021 and 2020 vaccination coverage by age group and vaccine type after one year of follow-up of the recovery plan. The Chi-square test was executed on proportions for the years 2021 vs 2020. Results were considered statistically significant at a two-tailed p-value ≤ 0.05.</p><p><strong>Results: </strong>36-month coverage rates were 92.5% for polio and 93.7% for measles-containing-vaccine, representing -0.3% and -1.8% decreases, respectively, as compared to 2020. By 8 years of age (booster doses), immunisation coverage was 80.7% for polio and 80.1% for measles, representing a -5.7% and -3.7%, respectively, compared to 2020. 36-month coverage was 56.6% for Men B (-5.0% as compared to 2020), 73.2% for Men ACW135Y/C (+1.1% as compared to 2020) and 86.9% for PNC vaccine (-1.7%, as compared to 2020). Regarding HPV vaccination, in 2021, vaccine coverage was 44.2% (-4.4% compared to 2020). Compared to the previous report, the VC difference among the cohorts narrowed for all almost vaccinations, except for the anti-men B and the anti-HPV vaccination, for which we recorded an increase in VC difference, and for men ACW135Y/C, for which a significant increase has been recorded.</p><p><strong>Conclusions: </strong>Despite the efforts to organize and realize an extensive and well-designed vaccination recovery, our data show that even after the 1-year follow-up, globally deficits in coverage for these routine vaccinations persist, although there has been a substantial and significant recovery of missed vaccinations, especially among younger children and for primary cycles.</p>","PeriodicalId":94106,"journal":{"name":"Journal of preventive medicine and hygiene","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10730062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138833688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimal timing of measles vaccination in high-risk areas: Insights from MR-1 administration and subsequent dosing efficacy. 高风险地区接种麻疹疫苗的最佳时机:从 MR-1 的接种和随后的剂量效力中获得启示。
Pub Date : 2023-11-01 eCollection Date: 2023-09-01 DOI: 10.15167/2421-4248/jpmh2023.64.3.3075
Sinu Jose
{"title":"Optimal timing of measles vaccination in high-risk areas: Insights from MR-1 administration and subsequent dosing efficacy.","authors":"Sinu Jose","doi":"10.15167/2421-4248/jpmh2023.64.3.3075","DOIUrl":"https://doi.org/10.15167/2421-4248/jpmh2023.64.3.3075","url":null,"abstract":"","PeriodicalId":94106,"journal":{"name":"Journal of preventive medicine and hygiene","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10730049/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138833695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of preventive medicine and hygiene
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