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VEXAS syndrome diagnosis starting from ultrasound findings: a case report. 从超声波检查结果诊断 VEXAS 综合征:病例报告。
Pub Date : 2024-09-16 Epub Date: 2024-05-28 DOI: 10.11152/mu-4384
Tamás Rácz, Sergiu Burciu, Tunde Torok, Laura Damian, Simona Rednic, Siao-Pin Simon

VEXAS syndrome is a recently described condition characterized by systemic inflammation, predisposition to hematologic malignancy and a high rate of venous thrombosis. Here we report the case of an elderly male with erythema nodosumlike lesions, ankle arthralgia, and general symptoms. B-mode and Doppler ultrasound of the subcutis diagnosed superficial thrombophlebitis of the lower limbs, which turned out to be the manifestation of a paucisymptomatic VEXAS syndrome. VEXAS should be considered in any patient who presents with unexplained superficial thrombophlebitis, macrocytic anemia and unexplained systemic inflammation.

VEXAS 综合征是最近描述的一种疾病,其特点是全身炎症、易患血液系统恶性肿瘤和静脉血栓形成率高。在此,我们报告了一例老年男性病例,他患有结节性红斑、踝关节痛和全身症状。皮下 B 型超声波和多普勒超声波诊断为下肢浅表血栓性静脉炎,而这正是无症状的 VEXAS 综合征的表现形式。任何出现不明原因的浅表血栓性静脉炎、巨幼红细胞性贫血和不明原因的全身炎症的患者都应考虑 VEXAS 综合征。
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引用次数: 0
Evaluation of the correlation of wall elasticity between different sections of radial artery by velocity vector imaging. 通过速度矢量成像评估桡动脉不同切面之间管壁弹性的相关性。
Pub Date : 2024-09-16 Epub Date: 2024-05-29 DOI: 10.11152/mu-4380
Ge Tong, Yihua Gao, Dandan Yuan

Aim: This study aimed to evaluate the correlation between the elasticity of the anterior and posterior walls of the radial artery in different sections using velocity vector imaging.

Material and methods: In this retrospective analysis, 30 healthy people who underwent physical examination in our hospital from January 2022 to January 2023 were analyzed offline by velocity vector imaging technology. The following parameters were assessed: peak systolic strain (Ss; %), peak diastolic strain (Sd; %), peak systolic strain rate (SRs; 1/s), and peak diastolic strain rate (SRd; 1/s). Elastic function was evaluated by analyzing the systolic and diastolic motion of the arterial walls.

Result: In the long-axis sections, there was a significant positive correlation between Ss, SRs, and SRd of both the anterior and posterior walls (r=0.531, r=0.803, and r=0.898, all p<0.01). Additionally, Sd showed a positive correlation (r=0.402, p<0.05). In the short-axis sections, there was a significant and positive correlation between SRs and SRd of both walls (r=0.762, r=0.667, both p<0.01). Furthermore, a positive correlation was found between SRd in the long-axis and short-axis sections of the anterior wall (r=0.382, p<0.05).

Conclusions: Velocity vector imaging is a valuable tool for assessing the elasticity of the radial artery in different sections, and the longitudinal SRd in the long-axis section may serve as a highly sensitive and accurate parameter for assessing changes in wall elastic function during the occurrence of radial artery lesions.

目的:本研究旨在利用速度矢量成像技术评估不同切面桡动脉前后壁弹性之间的相关性:在这项回顾性分析中,我们利用速度矢量成像技术对 2022 年 1 月至 2023 年 1 月期间在我院接受体检的 30 名健康人进行了离线分析。评估参数包括:收缩期峰值应变(Ss;%)、舒张期峰值应变(Sd;%)、收缩期峰值应变率(SRs;1/s)和舒张期峰值应变率(SRd;1/s)。通过分析动脉壁的收缩和舒张运动来评估弹性功能:结果:在长轴切面上,前后壁的 Ss、SRs 和 SRd 之间存在显著的正相关性(r=0.531、r=0.803 和 r=0.898,均为 p):速度矢量成像是评估桡动脉不同切面弹性的重要工具,长轴切面的纵向SRd可作为评估桡动脉病变过程中管壁弹性功能变化的高度敏感和准确的参数。
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引用次数: 0
Ultrasound-guided proximal-anterior axillary nerve block: a novel technique. 超声引导下的腋神经近端-前端阻滞:一种新技术。
Pub Date : 2024-09-16 DOI: 10.11152/mu-4426
Akiko Hata, Makoto Sato, Takayuki Kunisawa

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引用次数: 0
Ultrasound findings of non-Hodgkin's mantle cell lymphoma in the right inguinal region. 右腹股沟区非霍奇金套细胞淋巴瘤的超声检查结果。
Pub Date : 2024-09-16 DOI: 10.11152/mu-4427
Haotian Zhao, Xiaona Wang, Yaru Yan, Li Li

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引用次数: 0
Comments and illustrations of the WFUMB CEUS liver guidelines: Cystic fibrosis associated liver disease. WFUMB CEUS肝脏指南的注释和插图:囊性纤维化相关肝病。
Pub Date : 2024-09-16 Epub Date: 2023-10-26 DOI: 10.11152/mu-4297
Kathleen Möller, Thomas Friedrich, Ehsan Safai Zadeh, Christian Görg, Christian Jenssen, Michael Hocke, Chiara De Molo, Carla Serra, Yi Dong, Xin Wu Cui, Adrian Lim, Klaus Dirks, David Srivastava, Christoph F Dietrich

In this series of articles with comments and illustrations on the World Federation for Medicine and Biology (WFUMB) guidelines on contrast-enhanced ultrasound (CEUS) the topics of very rare focal liver lesions (FLL) are discussed. Improving the detection and characterization of the most common FLL are the main topics of these guidelines. The focus of this review is on the many manifestations of cystic fibrosis-related liver disease (CFLD). These include focal biliary fibrosis, liver cirrhosis, vascular manifestations with nodular regenerative hyperplasia and portal hypertension with or without cirrhosis. This article describes the diverse changes of liver involvement in cystic fibrosis and their appearance on ultrasound, duplex sonography, and contrast enhanced ultrasonography. This knowledge and the imaging should help to recognize liver manifestations in time and enable a correct interpretation of ultrasound images in CF in the corresponding clinical situation.

在这一系列对世界医学与生物学联合会(WFUMB)超声造影(CEUS)指南的评论和插图文章中,讨论了非常罕见的局灶性肝损伤(FLL)的主题。改进最常见FLL的检测和表征是这些指南的主要主题。这篇综述的重点是囊性纤维化相关肝病(CFLD)的许多表现。其中包括局灶性胆汁纤维化、肝硬化、伴有结节性再生性增生的血管表现以及伴有或不伴有肝硬化的门静脉高压。本文描述了囊性纤维化肝脏受累的各种变化及其在超声、双相超声和增强超声上的表现。这些知识和成像应有助于及时识别肝脏表现,并在相应的临床情况下正确解释CF中的超声图像。
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引用次数: 0
Comments on and illustrations of the WFUMB CEUS liver guidelines: Rare malignant mesenchymal liver lesions. 对 WFUMB CEUS 肝脏指南的评论和说明:罕见恶性肝间质病变。
Pub Date : 2024-09-16 Epub Date: 2023-11-22 DOI: 10.11152/mu-4302
Ehsan Safai Zadeh, Nicole Schreiber, Christian Görg, Katharina Paulina Huber, Kathleen Möller, Analisa Berzigotti, Thomas Thomsen, Christian Jenssen, Ernst-Michael Jung, Adrian Lim, Masayuki Kitano, Ryo Shimizu, Yi Dong, Xin Wu Cui, David Srivastava, Christoph F Dietrich

The diagnosis or rare mesenchymal malignant lesions of the liver may be a challenge owing to the rarity of the disease and is usually made by histological confirmation. An ultrasound examination with, if required, color Doppler sonography and contrast-enhanced ultrasound, taking into account the clinical background of the patient, may help to focus the differential diagnosis. In this review, we describe the pathological and ultrasound features of several rare mesenchymal malignant liver lesions which include undifferentiated sarcoma of the liver, leiomyosarcoma, angiosarcoma, fibrosarcoma, liposarcoma, and epithelioid hemangioendothelioma.

由于罕见,肝脏间质恶性病变的诊断可能是一项挑战,通常需要通过组织学确诊。根据患者的临床背景,必要时进行超声检查,包括彩色多普勒超声检查和对比增强超声检查,可以帮助确定鉴别诊断的重点。在这篇综述中,我们描述了几种罕见肝脏间质恶性病变的病理和超声特征,其中包括肝未分化肉瘤、亮肌肉瘤、血管肉瘤、纤维肉瘤、脂肪肉瘤和上皮样血管内皮瘤。
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引用次数: 0
Contrast-enhanced ultrasound versus conventional ultrasound in guided liver puncture biopsy: a systematic review and meta-analysis. 对比增强超声与传统超声在肝穿刺活检中的应用:系统回顾与荟萃分析。
Pub Date : 2024-09-16 Epub Date: 2024-05-29 DOI: 10.11152/mu-4374
Lidan Yang, Ting Zhang, Lei Wang, Juan Du, Hao Zhang, Wenquan Yi

Aim: To evaluate the contrast-enhanced ultrasound (CEUS) versus conventional ultrasound (US) in guided liver puncture biopsy through a systematic review and meta-analysis.

Material and methods: Comparative studies on CEUS and US in liver puncture biopsy were systematically searched from PubMed, Embase, Cochrane library, Chinese Biomedical Literature Database. Two researchers independently screened and extracted data, and RevMan 5.3 software was used for data analysis.

Results: The area under the curve (AUC) for CEUS and US in diagnosing liver biopsy was 0.98 (95%CI 0.99-0.97) and 0.95 (95%CI 0.97-0.93), respectively. CEUS demonstrated significantly higher single puncture success rate (38.0% vs 36.4%) [OR=2.67; 95% CI 1.38-5 .17; p=0 .003] and pathological diagnosis rate (95.6% vs 90.5%) [OR =4.35; 95%CI 2.25 -8.39; p<0 .001] compared to the US group. The diagnostic accuracy of the CEUS group was 95.6 % (1964/2054), while that of the US group was 90.5% (1729/1909). The combined analysis indicated significant advantages for CEUS over US [(OR = 2.36). 95 %CI 1.81-3.09, p<0.001].

Conclusions: CEUS is superior to US in the diagnostic performance, single puncture success rate, pathological diagnosis rate and diagnostic accuracy of liver biopsy in patients with liver lesions.

目的:通过系统综述和荟萃分析评估对比增强超声(CEUS)与传统超声(US)在肝穿刺活检中的应用:从PubMed、Embase、Cochrane图书馆、中国生物医学文献数据库中系统检索了肝穿刺活检中CEUS与US的比较研究。两名研究人员独立筛选和提取数据,并使用RevMan 5.3软件进行数据分析:CEUS和US诊断肝活检的曲线下面积(AUC)分别为0.98(95%CI 0.99-0.97)和0.95(95%CI 0.97-0.93)。CEUS的单次穿刺成功率(38.0% vs 36.4%)[OR=2.67;95%CI 1.38-5 .17;p=0.003]和病理诊断率(95.6% vs 90.5%)[OR=4.35;95%CI 2.25-8.39; p结论:CEUS在肝脏病变患者肝活检的诊断性能、单次穿刺成功率、病理诊断率和诊断准确性方面均优于US。
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引用次数: 0
The hidden menagerie of the posterolateral corner of the knee. 膝关节后外侧角隐藏的动物群。
Pub Date : 2024-09-16 DOI: 10.11152/mu-4422
Berkay Yalçınkaya, Ahmet Furkan Çolak, Ahmad Jasem Abdulsalam, Murat Kara

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引用次数: 0
The impact of deep learning on diagnostic performance in the differentiation of benign and malignant thyroid nodules. 深度学习对甲状腺结节良恶性鉴别诊断性能的影响。
Pub Date : 2024-09-04 DOI: 10.11152/mu-4432
Esat Kaba, Merve Solak, Ayşenur Topçu Varlık, Yusuf Çubukçu, Lütfullah Sağır, Kubilay Muhammed Sünnetci, Ahmet Alkan, Hasan Gündoğdu, Fatma Beyazal Çeliker, Mehmet Beyazal

Aims: This study aims to use deep learning (DL) to classify thyroid nodules as benign and malignant with ultrasonography (US). In addition, this study investigates the impact of DL on the diagnostic success of radiologists with different experiences. Material and methods: This study included 576 US images of thyroid nodules. The dataset was divided into 80% training and 20% test sets. Four radiologists with different levels of experience classified the images in the test set as benign-malignant. A DL model was then trained with the train set and predicted benign-malignant for the test set. Then, the output of the DL model for each nodule in the test set was presented to 4 radiologists, who were asked to make a benign-malignant classification again considering these DL results.

Results: The accuracy of the DL model was 0.9391. The accuracy for junior resident (JR) 1, JR 2, senior resident (SR), and senior radiologist (Srad) before DL-assisting were 0.7043, 0.7826, 0.8435, and 0.8522 respectively. The accuracy in DL-assisted classifications was 0.9130, 0.8696, 0.9304, and 0.9043 for JR 1, JR2, SR, and Srad, respectively. DL assistance changed the decisions of less experienced radiologists more than more experienced radiologists. Conclusion: The DL model has superior accuracy in classifying thyroid nodules as benign-malignant with US images than radiologists with different levels of experience. Additionally, all radiologists, and most notably less experienced radiology residents, increased their accuracy in DL-assisted predictions.

目的:本研究旨在利用深度学习(DL)对甲状腺结节进行良性和恶性超声波成像(US)分类。此外,本研究还探讨了深度学习对具有不同经验的放射科医生诊断成功率的影响。材料和方法:本研究包括 576 张甲状腺结节的 US 图像。数据集分为 80% 的训练集和 20% 的测试集。四名具有不同经验水平的放射科医生对测试集中的图像进行良恶性分类。然后用训练集训练 DL 模型,并预测测试集的良恶性。然后,将测试集中每个结节的 DL 模型输出结果提交给 4 位放射科医生,要求他们根据这些 DL 结果再次进行良恶性分类:结果:DL 模型的准确率为 0.9391。在 DL 辅助之前,初级住院医师 (JR) 1、JR 2、高级住院医师 (SR) 和高级放射科医师 (Srad) 的准确率分别为 0.7043、0.7826、0.8435 和 0.8522。在 DL 辅助下,JR 1、JR 2、SR 和 Srad 的分类准确率分别为 0.9130、0.8696、0.9304 和 0.9043。与经验丰富的放射科医生相比,经验不足的放射科医生在 DL 辅助下做出的决定变化更大。结论DL 模型在利用 US 图像将甲状腺结节分为良性-恶性方面的准确性优于不同经验水平的放射科医生。此外,所有放射科医生,尤其是经验较少的放射科住院医生,在 DL 辅助预测中的准确率都有所提高。
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引用次数: 0
Thrombosed persistent median artery in a medical sonographer. 一名医学超声技师的正中动脉血栓形成。
Pub Date : 2024-09-04 DOI: 10.11152/mu-4431
Stephen Leinfelder, Nicholas C Nacey

The use of gray-scale and color Doppler ultrasound as a first-line imaging modality for wrist pain can be advantageous, especially in cases of clinically suspected carpal tunnel syndrome. This report presents the case of a medical sonographer who exhibited acute wrist pain secondary to a thrombosed persistent median artery after excessive stress loading on her scanningwrist. Ultrasound is able to easily diagnose this rare condition, which may at times be associated with carpal tunnel symptoms due to mass effect from the expanded aberrant artery.

使用灰阶和彩色多普勒超声作为治疗腕痛的一线成像模式具有优势,尤其是在临床怀疑患有腕管综合征的病例中。本报告介绍了一名医学超声技师的病例,她在扫描时手腕承受了过大的压力负荷,继发于持续性正中动脉血栓形成,导致急性手腕疼痛。超声波能够轻松诊断出这种罕见病症,由于扩张的异常动脉产生的肿块效应,这种病症有时可能与腕管症状有关。
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引用次数: 0
期刊
Medical ultrasonography
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