Yi Dong, Beatrice Hoffmann, Simone Schwarz, Nasenien Nourkami-Tutdibi, Yun-Lin Huang, Sheng Chen, Andrius Cekuolis, Rasa Augustiniene, Peter J Snelling, Dagmar Schreiber-Dietrich, Lara Grevelding, Christoph F Dietrich
Emergency ultrasound, or point-of-care ultrasound (POCUS), has been established into daily patient care over the last decades. The use of abdominal and pelvic ultrasound in clinical practice has the potential to improve the efficiency and safety of pediatric emergency care. This article will provide a review of current applications of pediatric emergency abdominal and urogenital ultrasound, forming the second part of the series.
{"title":"An [illustrative] update on pediatric emergency medicine ultrasound: part 2 - abdominal and urogenital applications.","authors":"Yi Dong, Beatrice Hoffmann, Simone Schwarz, Nasenien Nourkami-Tutdibi, Yun-Lin Huang, Sheng Chen, Andrius Cekuolis, Rasa Augustiniene, Peter J Snelling, Dagmar Schreiber-Dietrich, Lara Grevelding, Christoph F Dietrich","doi":"10.11152/mu-4414","DOIUrl":"https://doi.org/10.11152/mu-4414","url":null,"abstract":"<p><p>Emergency ultrasound, or point-of-care ultrasound (POCUS), has been established into daily patient care over the last decades. The use of abdominal and pelvic ultrasound in clinical practice has the potential to improve the efficiency and safety of pediatric emergency care. This article will provide a review of current applications of pediatric emergency abdominal and urogenital ultrasound, forming the second part of the series.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141857504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniela Fodor, M. Pelea, M. Bădărînză, Carmen Georgiu, O. Șerban
Tuberculosis (TB) arthritis remains a diagnostic challenge. In addition to clinical presentation, the use of imaging techniques and confirmation of Mycobacterium tuberculosis are essential. We present the case of a 69-year-old female in whom the diagnosis of knee TB arthritis was simultaneously established with the diagnosis of MALT lymphoma. This case report aims to highlight the role of multimodal ultrasound (US) in both diagnosis and its utility in interventional procedures, such as aspiration and synovial biopsy.
{"title":"Knee tuberculosis in the context of MALT lymphoma: the diagnostic role of ultrasound and CEUS. A case report.","authors":"Daniela Fodor, M. Pelea, M. Bădărînză, Carmen Georgiu, O. Șerban","doi":"10.11152/mu-4410","DOIUrl":"https://doi.org/10.11152/mu-4410","url":null,"abstract":"Tuberculosis (TB) arthritis remains a diagnostic challenge. In addition to clinical presentation, the use of imaging techniques and confirmation of Mycobacterium tuberculosis are essential. We present the case of a 69-year-old female in whom the diagnosis of knee TB arthritis was simultaneously established with the diagnosis of MALT lymphoma. This case report aims to highlight the role of multimodal ultrasound (US) in both diagnosis and its utility in interventional procedures, such as aspiration and synovial biopsy.","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" 30","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141670570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yue Ma, Yang Li, Min Zhu, Shi-Yu Wang, Feng-Rong Yang, Yu-Qing Xu, Ru Yang, Ban-Ban Wu, Yi-Xue Sun
Aim: This study set out to access the performance of quantitative analysis of contrast-enhanced ultrasound (CEUS) in distinguishing between benign periablational enhancement (BPE) and residual tumor (RT) following radiofrequency ablation (RFA).
Materials and methods: 165 tumors from 124 patients with hepatocellular carcinoma between 2021 and 2023 underwent RFA, contrast-enhanced computed tomography (CECT), and CEUS in less than 24 hours. Analysis was done on the quantitative parameters from RT and BPE found by CEUS.
Results: Complete ablation was obtained in 89.1% of lesions. When compared to BPE, RT had significantly greater peak intensity (PI), time to peak (TTP), area under the curve (AUC), ratio of PI and base intensity (PI/BI), and enhanced intensity (EI) values (all p<0.05). PI, TTP, AUC, PI/BI, and EI had large areas under the receiver operating (ROC) curves. A binary logistic regression analysis, respectively, demonstrated that PI and PI/BI were independent favorable prognostic variables.
Conclusions: Multiple parameters of quantitative analysis of CEUS can aid in distinguishing immediately between RT and BPE lesions. PI and PI/BI may be a more promising parameter. Immediate CEUS evaluation following RFA may allow immediate retreatment of RT during the same operation time, which reduces patients' hospital stays and financial costs.
{"title":"The application of dynamic contrast-enhanced ultrasonography in immediate distinguishing residual tumour from benign periablational enhancement after hepatocellular carcinoma radiofrequency ablation.","authors":"Yue Ma, Yang Li, Min Zhu, Shi-Yu Wang, Feng-Rong Yang, Yu-Qing Xu, Ru Yang, Ban-Ban Wu, Yi-Xue Sun","doi":"10.11152/mu-4394","DOIUrl":"https://doi.org/10.11152/mu-4394","url":null,"abstract":"<p><strong>Aim: </strong>This study set out to access the performance of quantitative analysis of contrast-enhanced ultrasound (CEUS) in distinguishing between benign periablational enhancement (BPE) and residual tumor (RT) following radiofrequency ablation (RFA).</p><p><strong>Materials and methods: </strong>165 tumors from 124 patients with hepatocellular carcinoma between 2021 and 2023 underwent RFA, contrast-enhanced computed tomography (CECT), and CEUS in less than 24 hours. Analysis was done on the quantitative parameters from RT and BPE found by CEUS.</p><p><strong>Results: </strong>Complete ablation was obtained in 89.1% of lesions. When compared to BPE, RT had significantly greater peak intensity (PI), time to peak (TTP), area under the curve (AUC), ratio of PI and base intensity (PI/BI), and enhanced intensity (EI) values (all p<0.05). PI, TTP, AUC, PI/BI, and EI had large areas under the receiver operating (ROC) curves. A binary logistic regression analysis, respectively, demonstrated that PI and PI/BI were independent favorable prognostic variables.</p><p><strong>Conclusions: </strong>Multiple parameters of quantitative analysis of CEUS can aid in distinguishing immediately between RT and BPE lesions. PI and PI/BI may be a more promising parameter. Immediate CEUS evaluation following RFA may allow immediate retreatment of RT during the same operation time, which reduces patients' hospital stays and financial costs.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141857507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chae Woon Lee, Dae Young Yoon, Sora Baek, Hyung Jin Lee, Eun Soo Kim, Kyoung Ja Lim, Young Lan Seo, Eun Joo Yun
Aim: To determine the ultrasonographic (US) features that could help to distinguish between parathyroid masses abutting the thyroid gland and thyroid masses extending into the parathyroid area.
Materials and methods: Two blinded readers retrospectively evaluated the US images of 76 histopathologically confirmed parathyroid masses abutting the thyroid gland and 34 thyroid masses extending into the parathyroid area. Maximal diameter, transverse diameter/anterior-posterior diameter (T/AP) ratio, longitudinal diameter/AP diameter (L/AP) ratio, margin, shape, echogenicity, echotexture, and echogenic interface were evaluated and compared between the two groups.
Results: Echogenic interface (p<0.001) and L/AP ratio (p<0.001) were statistically significant US features that differentiated parathyroid and thyroid masses. Other US features did not show any significant differences between the two groups. Interobserver agreement was excellent for all US features. Sensitivity/specificity of the presence of echogenic interface and L/AP ratio >2.0 were 85.5%/100% and 43.2%/82.4% in distinguishing parathyroid from thyroid masses, respectively.
Conclusion: The presence of an echogenic interface and L/AP ratio >2.0 were useful US features for differentiating parathyroid masses abutting the thyroid gland from thyroid masses extending into theparathyroid area.
{"title":"Can ultrasonography be used to differentiate parathyroid masses abutting the thyroid gland from thyroid masses extending into the parathyroid area?","authors":"Chae Woon Lee, Dae Young Yoon, Sora Baek, Hyung Jin Lee, Eun Soo Kim, Kyoung Ja Lim, Young Lan Seo, Eun Joo Yun","doi":"10.11152/mu-4393","DOIUrl":"https://doi.org/10.11152/mu-4393","url":null,"abstract":"<p><strong>Aim: </strong>To determine the ultrasonographic (US) features that could help to distinguish between parathyroid masses abutting the thyroid gland and thyroid masses extending into the parathyroid area.</p><p><strong>Materials and methods: </strong>Two blinded readers retrospectively evaluated the US images of 76 histopathologically confirmed parathyroid masses abutting the thyroid gland and 34 thyroid masses extending into the parathyroid area. Maximal diameter, transverse diameter/anterior-posterior diameter (T/AP) ratio, longitudinal diameter/AP diameter (L/AP) ratio, margin, shape, echogenicity, echotexture, and echogenic interface were evaluated and compared between the two groups.</p><p><strong>Results: </strong>Echogenic interface (p<0.001) and L/AP ratio (p<0.001) were statistically significant US features that differentiated parathyroid and thyroid masses. Other US features did not show any significant differences between the two groups. Interobserver agreement was excellent for all US features. Sensitivity/specificity of the presence of echogenic interface and L/AP ratio >2.0 were 85.5%/100% and 43.2%/82.4% in distinguishing parathyroid from thyroid masses, respectively.</p><p><strong>Conclusion: </strong>The presence of an echogenic interface and L/AP ratio >2.0 were useful US features for differentiating parathyroid masses abutting the thyroid gland from thyroid masses extending into theparathyroid area.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141857506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eric Matschiner, Oana Serban, Daniela Fodor, Michael Blaivas, Rudolf Horn, Jonas Koch, Marie-Lise Jakobi, Lara Grevelding, Joseph Osterwalder, David Srivastava, Christoph Frank Dietrich
Aim: This meta-analysis evaluates the diagnostic accuracy of ultrasound (US) for bone fractures over the past 47 years, comparing it to established imaging standards.
Material and methods: We adhered to PRISMA 2020 guidelines to search Medline, EMBASE, and the Cochrane Library using tailored search strategies. The primary outcome, US diagnostic performance, was analyzed across various subgroups including clinical relevance, patient age, and anatomical considerations. The QUADAS-2 tool was employed to assess study quality and minimize bias.
Results: From 5,107 initially identified studies, 75 met the inclusion criteria, encompassing 7,769 participants and 3,575 diagnosed fractures. The majority of studies were prospective (79%) and compared US primarily with plain radiography (76%) and CT scans (19%). Of these, 61 studies were amenable to systematic analysis, revealing US to have a sensitivity and specificity of 91% (95% CI: 90%-92%) and 91.3% (95% CI: 90.5%-92.1%), respectively. Likelihood ratios were favorable, with a positive value of 9.955 and a negative value of 0.087, and an odds ratio of 132.67. The area under the curve stood at 0.9715, indicating high diagnostic accuracy despite significant heterogeneity (I²=81.3% for sensitivity, 89.3% for specificity).
Conclusion: The evidence supports US as a highly accurate diagnostic tool for bone fractures, rivalling standard imaging methods like CT and radiography. Its notable diagnostic efficacy, combined with advantages in reducing pain, wait times, and radiation exposure, advocates for its broader application. Further validation in large-scale, randomized trials is essential to integrate US more fully into clinical guidelines for fracture management.
{"title":"Ultrasound in bone fracture diagnosis - a comparative meta-analysis and systematic review.","authors":"Eric Matschiner, Oana Serban, Daniela Fodor, Michael Blaivas, Rudolf Horn, Jonas Koch, Marie-Lise Jakobi, Lara Grevelding, Joseph Osterwalder, David Srivastava, Christoph Frank Dietrich","doi":"10.11152/mu-4407","DOIUrl":"https://doi.org/10.11152/mu-4407","url":null,"abstract":"<p><strong>Aim: </strong>This meta-analysis evaluates the diagnostic accuracy of ultrasound (US) for bone fractures over the past 47 years, comparing it to established imaging standards.</p><p><strong>Material and methods: </strong>We adhered to PRISMA 2020 guidelines to search Medline, EMBASE, and the Cochrane Library using tailored search strategies. The primary outcome, US diagnostic performance, was analyzed across various subgroups including clinical relevance, patient age, and anatomical considerations. The QUADAS-2 tool was employed to assess study quality and minimize bias.</p><p><strong>Results: </strong>From 5,107 initially identified studies, 75 met the inclusion criteria, encompassing 7,769 participants and 3,575 diagnosed fractures. The majority of studies were prospective (79%) and compared US primarily with plain radiography (76%) and CT scans (19%). Of these, 61 studies were amenable to systematic analysis, revealing US to have a sensitivity and specificity of 91% (95% CI: 90%-92%) and 91.3% (95% CI: 90.5%-92.1%), respectively. Likelihood ratios were favorable, with a positive value of 9.955 and a negative value of 0.087, and an odds ratio of 132.67. The area under the curve stood at 0.9715, indicating high diagnostic accuracy despite significant heterogeneity (I²=81.3% for sensitivity, 89.3% for specificity).</p><p><strong>Conclusion: </strong>The evidence supports US as a highly accurate diagnostic tool for bone fractures, rivalling standard imaging methods like CT and radiography. Its notable diagnostic efficacy, combined with advantages in reducing pain, wait times, and radiation exposure, advocates for its broader application. Further validation in large-scale, randomized trials is essential to integrate US more fully into clinical guidelines for fracture management.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141857470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-21Epub Date: 2023-10-04DOI: 10.11152/mu-4287
Kathleen Moller, Oliver Hoffmann, Ehsan Safai Zadeh, Christian Gorg, Christian Jenssen, Michael Hocke, Chiara De Molo, Carla Serra, Yi Dong, Xin Wu Cui, Adrian Lim, Klaus Dirks, Siegbert Faiss, David Srivastava, Christoph F Dietrich
In this series of articles on comments and illustrations of the World Federation for Medicine and Biology (WFUMB) guidelines on contrast-enhanced ultrasound (CEUS), the topics on very rare focal liver lesions (FLL) are discussed. This article describes the diverse changes of focal liver lesions in peliosis hepatis and the typical changes in porphyria. Although the focus is on the appearance on ultrasound and CEUS, the clinical context is always considered. While peliosis may be a surprising finding on puncture, lesions in porphyria cutanea tarda may be typical visual diagnoses that obviate the need for biopsy. If only you knew. This article aims to sharpen the clinician's eye. It provides knowledge of the clinical presentation and US and CEUS imaging of peliosis hepatis and porphyria.
{"title":"Comments and illustrations of the WFUMB CEUS liver guidelines: Peliosis hepatis and porphyria.","authors":"Kathleen Moller, Oliver Hoffmann, Ehsan Safai Zadeh, Christian Gorg, Christian Jenssen, Michael Hocke, Chiara De Molo, Carla Serra, Yi Dong, Xin Wu Cui, Adrian Lim, Klaus Dirks, Siegbert Faiss, David Srivastava, Christoph F Dietrich","doi":"10.11152/mu-4287","DOIUrl":"10.11152/mu-4287","url":null,"abstract":"<p><p>In this series of articles on comments and illustrations of the World Federation for Medicine and Biology (WFUMB) guidelines on contrast-enhanced ultrasound (CEUS), the topics on very rare focal liver lesions (FLL) are discussed. This article describes the diverse changes of focal liver lesions in peliosis hepatis and the typical changes in porphyria. Although the focus is on the appearance on ultrasound and CEUS, the clinical context is always considered. While peliosis may be a surprising finding on puncture, lesions in porphyria cutanea tarda may be typical visual diagnoses that obviate the need for biopsy. If only you knew. This article aims to sharpen the clinician's eye. It provides knowledge of the clinical presentation and US and CEUS imaging of peliosis hepatis and porphyria.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" ","pages":"178-186"},"PeriodicalIF":0.0,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71490646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unexpected finding: a patient with choledocholithiasis found mass at the lower end of common bile duct.","authors":"Wei Zhang, Sen-Lin Hou, Kun Lian, Jiao Tian, Yan-Kun Hou, Li-Chao Zhang","doi":"10.11152/mu-4404","DOIUrl":"10.11152/mu-4404","url":null,"abstract":"<p><p>.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":"26 2","pages":"220-221"},"PeriodicalIF":0.0,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141444059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-21Epub Date: 2023-12-23DOI: 10.11152/mu-4315
Ping Yang, Chao Zhang, Yaping Zhang, Qingsong Liu, Hong Shi
Preoperative diagnosis of gallbladder tuberculosis (TB) is difficult, and the contrast-enhanced ultrasound (CEUS) pattern has never been reported before. We present a case of TB in which CEUS had some special findings that were helpful for early diagnosis. The thickened gallbladder wall presented in the arterial phase of CEUS the "sandwich biscuit" sign with no enhancement in the middle layer and hyperenhancement in the inner and outer layers.
{"title":"Contrast-enhanced ultrasound findings of gallbladder tuberculosis: a case report.","authors":"Ping Yang, Chao Zhang, Yaping Zhang, Qingsong Liu, Hong Shi","doi":"10.11152/mu-4315","DOIUrl":"10.11152/mu-4315","url":null,"abstract":"<p><p>Preoperative diagnosis of gallbladder tuberculosis (TB) is difficult, and the contrast-enhanced ultrasound (CEUS) pattern has never been reported before. We present a case of TB in which CEUS had some special findings that were helpful for early diagnosis. The thickened gallbladder wall presented in the arterial phase of CEUS the \"sandwich biscuit\" sign with no enhancement in the middle layer and hyperenhancement in the inner and outer layers.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" ","pages":"205-207"},"PeriodicalIF":0.0,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139049942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Piezogenic papules.","authors":"Olivier Lebecque, Ana Falticeanu, Nicolas Mulquin","doi":"10.11152/mu-4398","DOIUrl":"10.11152/mu-4398","url":null,"abstract":"<p><p>.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":"26 2","pages":"213-214"},"PeriodicalIF":0.0,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141444055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}