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[Self-reported quality of life of pediatric patients discharged from the Intensive Care Unit]. [重症监护病房出院儿童患者自我报告的生活质量]。
Pub Date : 2025-04-15
Adriana Marcela Monroy Garzón, David Andrade Fonseca, Diana Alejandra Ruiz Rodríguez, María Zoraida Rojas, Eddison Ramírez-Merchán, Alexander Casallas-Vega

Objective: The experience of hospitalization in the Pediatric Intensive Care Unit (PICU) affects several dimensions of the quality of life of the pediatric patient at discharge. These effects may be related to factors such as diagnoses, invasive procedures and disruption of their family ties. The objective was to measure the quality of life of children discharged from the PICU area, using the Kidscreen self-reporting instrument 27.

Methods: A quantitative approach of the analytical observational type was carried out, the population was made up of children who were hospitalized in the PICU for more than forty-eight hours and who are in their home environment. The Kidscreen 27 instrument was applied, which evaluated five dimensions of quality of life to forty-seven children between eight and eighteen years old. The correlation analysis used was the Mann-Whitney U statistical test.

Results: The results showed statistical significant differences in quality of life between genders with a P value=0.002, with lower scores in physical activity in girls. Furthermore, respiratory pathologies were the main cause of admission to the PICU with 27.6%, highlighting the importance of family and social support. Finally, 89.9% of children underwent catheter and probe insertion procedures.

Conclusions: Multidisciplinary interventions and the need for a holistic approach in post-ICU care are required, with the aim of improving the quality of life of children and being able to reduce sequelae during their re-entry into society.

目的:儿童重症监护病房(PICU)的住院经历影响儿童出院时生活质量的几个方面。这些影响可能与诊断、侵入性手术和家庭关系破裂等因素有关。目的是使用Kidscreen自我报告工具27来衡量从PICU区出院的儿童的生活质量。方法:采用分析观察型的定量方法,研究对象为在PICU住院48小时以上的家庭环境儿童。使用了Kidscreen 27仪器,对47名8至18岁的儿童的生活质量进行了五个方面的评估。相关分析采用Mann-Whitney U统计检验。结果:两性生活质量差异有统计学意义,P值为0.002,女生的体育活动得分较低。此外,呼吸系统疾病是PICU入院的主要原因,占27.6%,突出了家庭和社会支持的重要性。最后,89.9%的儿童接受了导管和探针插入手术。结论:icu后护理需要多学科干预和整体方法,目的是提高儿童的生活质量,并能够减少其重返社会时的后遗症。
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引用次数: 0
[The role of international research stays and the European context of polio control in Spain]. [国际研究的作用和西班牙小儿麻痹症控制的欧洲背景]。
Pub Date : 2025-04-09
Mª Victoria Caballero Martínez, María Isabel Porras Gallo

The epidemic emergence of poliomyelitis in Europe at the end of the 19th century and its global epidemic progression in the following decades generated great social concern and prompted the international fight against the disease, especially after 1953, when the World Health Organization (WHO) considered it an important international Public Health problem. Spain recorded small outbreaks, which became more intense after the Spanish Civil War and, particularly after 1950. In the middle of that decade, the first vaccines became available in the USA and Europe, and became the main tools to control polio. In Spain, Florencio Pérez Gallardo, from the National School of Public Health, led the work to study the magnitude of the disease and produce his own vaccine, for which he required international support. Within the framework of the social history of medicine, and using varied sources, our work places the Spanish vaccination strategy in the European context, highlighting the delay in its initiation and the deficiencies in its materialization. In addition, it analyses the role played by the international research stays of Pérez Gallardo and his team in order to overcome some limitations and, in 1963, to carry out the first national immunization campaign with Sabin vaccine, packaged by IBYS laboratories, showing the weight carried by their international relations, particularly with Albert Sabin.

19世纪末,脊髓灰质炎在欧洲的流行及其在随后几十年的全球流行进程引起了极大的社会关注,并促使国际上与该疾病作斗争,特别是在1953年之后,世界卫生组织(WHO)将其视为一个重要的国际公共卫生问题。西班牙记录了小规模的疫情,在西班牙内战之后,特别是在1950年之后,疫情变得更加严重。在那个年代中期,第一批疫苗在美国和欧洲问世,并成为控制脊髓灰质炎的主要工具。在西班牙,来自国家公共卫生学院的Florencio psamurez Gallardo领导了研究该疾病规模的工作,并生产了他自己的疫苗,为此他需要国际支持。在医学社会史的框架内,利用各种来源,我们的工作将西班牙疫苗接种战略置于欧洲背景下,突出其启动的延迟和实现的缺陷。此外,报告还分析了psamurez Gallardo及其小组的国际研究人员在克服某些限制方面所发挥的作用,并于1963年利用IBYS实验室包装的Sabin疫苗开展了第一次全国免疫运动,显示了他们的国际关系,特别是与Albert Sabin的关系所发挥的作用。
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引用次数: 0
[The unremitting threat: enterovirus D68, acute flaccid myelitis, and epidemiological surveillance]. [不间断的威胁:D68 型肠道病毒、急性弛缓性脊髓炎和流行病学监测]。
Pub Date : 2025-04-03
Cristina Guijarro-Castro, María Cabrerizo Sanz, Josefa Masa Calles
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引用次数: 0
[Cost and percentage of health expenditure for the care of patients with Human Immunodeficiency Virus in treatment with antiretrovirals]. [用抗逆转录病毒药物治疗人类免疫缺陷病毒患者的费用和占保健支出的百分比]。
Pub Date : 2025-04-01
Blanca Iris García Díaz, Verónica Escorcia Reyes, Enrique Villareal Ríos, Liliana Galicia Rodríguez

Objective: The disease generates cost in care and the cost of comprehensive care for the Human Immunodeficiency Virus (HIV) has an impact on the health budget. The objective of this paper was to determine the cost and percentage of health expenditure including medicines in the care of patients with HIV on antiretroviral treatment.

Methods: A cost study in patients diagnosed with HIV using information from the first and second level of care electronic clinical records was carried out. We worked with 246 patients that made up the total number of those existing at the time of the study. The profile of use of health services, fixed unit cost, variable unit cost, average unit cost, average annual cost per patient, annual cost for a population, and budget exercised by level of care were identified by level of care. The percentage of health spending was estimated based on spending on HIV and the budget spent at each level of care. Statistical analysis included averages percentages and projections.

Results: The average annual cost at the first level of care was €55.86, at the second level of care €628.30. The average annual cost per patient was €684.16 and the percentage of HIV health spending was 1.41%.

Conclusions: The cost of care for patients with human immunodeficiency virus is high and varies depending on the services used; in the same way the percentage of health expenditure shows the same trend if the percentage of the affected population is considered.

目的:艾滋病产生医疗费用,艾滋病综合医疗费用对卫生预算产生影响。本文的目的是确定艾滋病毒患者接受抗逆转录病毒治疗的费用和卫生支出(包括药品)的百分比。方法:利用一、二级医疗电子病历资料对诊断为HIV的患者进行成本研究。我们研究了246名患者,这些患者构成了研究时存在的患者总数。保健服务的使用概况、固定单位成本、可变单位成本、平均单位成本、每位患者的平均年成本、人口的年成本以及按护理水平行使的预算均按护理水平确定。保健支出的百分比是根据防治艾滋病毒的支出和各级护理的预算估算的。统计分析包括平均百分比和预测。结果:一级护理的年平均费用为55.86欧元,二级护理的年平均费用为628.30欧元。每位患者的平均年费用为684.16欧元,艾滋病毒卫生支出的百分比为1.41%。结论:人类免疫缺陷病毒患者的护理费用很高,并且根据所使用的服务而有所不同;同样,如果考虑到受影响人口的百分比,保健支出的百分比也显示出同样的趋势。
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引用次数: 0
[Artificial intelligence in Public Health: opportunities, ethical challenges and future perspectives]. [公共卫生中的人工智能:机遇、伦理挑战和未来展望]。
Pub Date : 2025-03-26
Sergio Castaño Castaño

Artificial Intelligence (AI) is transforming Public Health by providing innovative tools to address complex global challenges. Its ability to analyze large volumes of data in real time enhances epidemiological surveillance, optimizes healthcare resource management, and personalizes preventive interventions. These applications have proven valuable in situations such as pandemics, where AI algorithms have contributed to outbreak prediction, efficient resource allocation, and the design of targeted strategies. However, the adoption of AI also raises significant ethical and regulatory challenges. Issues such as data privacy, algorithmic transparency, and biases in models highlight the need for robust regulatory frameworks to ensure its ethical and equitable use. Furthermore, the lack of training among Public Health professionals and the digital literacy of communities limit the potential impact of these technologies. This article examines the practical applications, ethical challenges, and strategies needed for the responsible adoption of AI in Public Health. It emphasizes the importance of training, interdisciplinary collaboration, and continuous research to ensure that AI becomes a transformative tool contributing to global well-being. If implemented ethically and sustainably, AI can play a crucial role in promoting equity and quality in Public Health systems.

人工智能(AI)为应对复杂的全球挑战提供了创新工具,正在改变公共卫生。人工智能能够实时分析大量数据,从而加强流行病学监测、优化医疗资源管理和个性化预防干预。事实证明,这些应用在大流行病等情况下非常有价值,人工智能算法有助于预测疫情爆发、有效分配资源和设计有针对性的策略。然而,人工智能的应用也带来了伦理和监管方面的重大挑战。数据隐私、算法透明度和模型中的偏差等问题突出表明,需要建立强有力的监管框架,以确保人工智能的道德和公平使用。此外,公共卫生专业人员缺乏培训以及社区的数字扫盲也限制了这些技术的潜在影响。本文探讨了在公共卫生领域负责任地采用人工智能所需的实际应用、伦理挑战和策略。文章强调了培训、跨学科合作和持续研究的重要性,以确保人工智能成为促进全球福祉的变革性工具。如果以合乎道德和可持续的方式实施,人工智能可以在促进公共卫生系统的公平和质量方面发挥至关重要的作用。
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引用次数: 0
[The role of the National Polio Laboratory and the network of Sub-National Laboratories in the eradication of poliomyelitis in Spain]. [西班牙国家脊髓灰质炎实验室和次国家实验室网络在根除脊髓灰质炎方面的作用]。
Pub Date : 2025-03-21
María Cabrerizo, Mª Dolores Fernández-García

The aim of this paper was to describe the activities carried out by the National Poliovirus Laboratory (LNP) and the Spanish Acute Flaccid Paralysis (AFP) Surveillance Network. The LNP coordinates the network since 1998 and is responsible for the characterization of polioviruses (PV) and other enteroviruses (EV) detected, using cell culture and molecular methods. It is annually accredited by WHO and represents Spain in the World Health Organization European Polio Laboratory Network. In addition to the reported AFP cases, the network has analyzed since its creation an average of 9,000 clinical samples annually for EV, with a 7% of positive results. Two surveillance periods can be distinguished in Spain: from 1998 to 2004, when vaccine PV could be detected due to the use of the oral polio vaccine, and from 2005 onwards, when only three cases of imported vaccine-derived poliovirus have been identified following the introduction of the inactivated polio vaccine. In addition, between 70% and 85% of the EV samples received at the LNP are successfully genotyped. The work carried out by the lab network has contributed to the epidemiological and clinical surveillance and research of these infections, as well as to the rapid detection and characterization of imported poliomyelitis cases. This has facilitated the timely implementation of appropriate measures to prevent PV transmission and circulation in our country, in alignment with the Global Polio Eradication Initiative.

本文的目的是描述国家脊髓灰质炎病毒实验室(LNP)和西班牙急性弛缓性麻痹(AFP)监测网开展的活动。LNP自1998年以来协调该网络,并负责利用细胞培养和分子方法鉴定检测到的脊髓灰质炎病毒和其他肠病毒。它每年获得世卫组织的认可,并代表西班牙加入世界卫生组织欧洲小儿麻痹症实验室网络。除了报告的AFP病例外,该网络自创建以来平均每年分析9000例EV临床样本,阳性结果为7%。在西班牙可以区分两个监测时期:1998年至2004年,由于使用口服脊髓灰质炎疫苗,可以检测到疫苗PV; 2005年以来,在引入灭活脊髓灰质炎疫苗后,只发现了三例进口疫苗衍生脊髓灰质炎病毒。此外,LNP收到的EV样本中有70%至85%成功地进行了基因分型。实验室网络开展的工作有助于对这些感染进行流行病学和临床监测和研究,并有助于迅速发现和确定输入性脊髓灰质炎病例。这有助于及时实施适当措施,防止我国的PV传播和流通,与全球根除脊髓灰质炎行动保持一致。
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引用次数: 0
[Association between cardiorespiratory fitness and mortality risk in the chilean population]. [智利人口心肺健康与死亡风险之间的关系]。
Pub Date : 2025-03-20
Jaime Vásquez-Gómez, Yeny Concha-Cisternas, Solange Parra-Soto, Daniel Reyes-Molina, Felipe Díaz-Toro, Fanny Petermann-Rocha, Carlos Celis-Morales

Objective: Cardiorespiratory fitness reduces the risk of cardiometabolic diseases, cancer and mortality. The aim of this paper was to evaluate the relationship between equation-estimated cardiorespiratory fitness and all-cause mortality in the Chilean population of both genders according to data from the 2009-2010 National Health Survey (NHS).

Methods: Data from 4,749 participants from the 2009-2010 NHS were analysed after 10.9 years of follow-up. Fitness was estimated with the Myers et al. equation and classified into quintiles. All-cause mortality records were obtained from the Chilean Civil Registry and Identification until 2020. Cox regression models adjusted for confounding variables (demographics, nutritional status, lifestyle and comorbidities) were used to assess the association between fitness and mortality.

Results: During the 10.9 years (IQR: 10.8; 11.4) of follow-up 506 (10.6%) people died. Compared to the lowest fitness quintile (<7 METs) those classified in the highest quintile (>12 METs) had a 95% lower risk of mortality (HR: 0.05; 95% CI: 0.03, 0.09) and the risk of mortality was 28% lower for every 1-METs increase in fitness (HR: 0.72 95% CI: 0.69, 0.75). All these associations were independent of confounders.

Conclusions: We conclude that a higher level of fitness is associated with a lower risk of mortality independent of confounding factors in the Chilean population after 10.9 years of follow-up.

目的:心肺健康降低心脏代谢疾病、癌症和死亡率的风险。本文的目的是根据2009-2010年全国健康调查(NHS)的数据,评估智利男女人口中方程估计的心肺适能与全因死亡率之间的关系。方法:在10.9年的随访后,分析了来自2009-2010年NHS的4,749名参与者的数据。适应度用Myers等人的方程估计,并按五分位数分类。从智利民事登记和身份识别处获得了截至2020年的全因死亡率记录。采用校正了混杂变量(人口统计学、营养状况、生活方式和合并症)的Cox回归模型来评估健康与死亡率之间的关系。结果:10.9年(IQR: 10.8;随访506人(10.6%)死亡11.4人。与最低健康五分位数(12 METs)相比,死亡风险降低95% (HR: 0.05;95% CI: 0.03, 0.09),健康水平每增加1 mets,死亡风险降低28% (HR: 0.72, 95% CI: 0.69, 0.75)。所有这些关联都独立于混杂因素。结论:在10.9年的随访后,我们得出结论,在智利人群中,较高的健康水平与较低的死亡率风险相关,独立于混杂因素。
{"title":"[Association between cardiorespiratory fitness and mortality risk in the chilean population].","authors":"Jaime Vásquez-Gómez, Yeny Concha-Cisternas, Solange Parra-Soto, Daniel Reyes-Molina, Felipe Díaz-Toro, Fanny Petermann-Rocha, Carlos Celis-Morales","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>Cardiorespiratory fitness reduces the risk of cardiometabolic diseases, cancer and mortality. The aim of this paper was to evaluate the relationship between equation-estimated cardiorespiratory fitness and all-cause mortality in the Chilean population of both genders according to data from the 2009-2010 National Health Survey (NHS).</p><p><strong>Methods: </strong>Data from 4,749 participants from the 2009-2010 NHS were analysed after 10.9 years of follow-up. Fitness was estimated with the Myers et al. equation and classified into quintiles. All-cause mortality records were obtained from the Chilean Civil Registry and Identification until 2020. Cox regression models adjusted for confounding variables (demographics, nutritional status, lifestyle and comorbidities) were used to assess the association between fitness and mortality.</p><p><strong>Results: </strong>During the 10.9 years (IQR: 10.8; 11.4) of follow-up 506 (10.6%) people died. Compared to the lowest fitness quintile (<7 METs) those classified in the highest quintile (>12 METs) had a 95% lower risk of mortality (HR: 0.05; 95% CI: 0.03, 0.09) and the risk of mortality was 28% lower for every 1-METs increase in fitness (HR: 0.72 95% CI: 0.69, 0.75). All these associations were independent of confounders.</p><p><strong>Conclusions: </strong>We conclude that a higher level of fitness is associated with a lower risk of mortality independent of confounding factors in the Chilean population after 10.9 years of follow-up.</p>","PeriodicalId":94199,"journal":{"name":"Revista espanola de salud publica","volume":"99 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143757008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Association of Physical Activity, Mental Health and Contextual Factors with Problematic Internet Use in Adolescents from Barcelona: A Cross-sectional Study]. [体育活动、心理健康和环境因素与巴塞罗那青少年网络使用问题的关联:一项横断面研究]。
Pub Date : 2025-03-12
Marc Olivella-Cirici, Inés Nicolao-Usechi, Esther Sánchez-Ledesma, Gemma Serral, Catrina Clotas, Xavier Continente, Katherine Pérez, Gloria Pérez

Objective: Physical activity (PA) may be key to reducing problematic Internet use (PIU) among adolescents. Given that Internet usage patterns and PA participation can vary significantly across genders and different age groups, this study aims to analyze the association between PIU and PA, mental health and other contextual factors, in students aged thirteen to nineteen in Barcelona, by sex and age.

Methods: A cross-sectional study using data from the 2021 FRESC Survey was carried out, which included 3,256 students in the city of Barcelona. The dependent variable was PIU, measured with the validated CIUS scale. Poisson regression was used to estimate crude and adjusted prevalence ratios (PRa) with 95% confidence intervals (IC95%).

Results: In the group over sixteen years old, lower PIU was associated with regular PA in girls (PRa=0.62, IC95%=0.39-0.97) and in boys (PRa=0.51, IC95%=0.35-0.74). Lower PIU in girls under sixteen was associated with higher frequency of sports activities (PRa=0.53, IC95%=0.31-0.88). Poor mental health was associated with higher PIU across all groups (boys under sixteen, PRa=3.31, IC95%=2.42-4.51).

Conclusions: PA is associated with lower PIU in all groups except boys under sixteen years old. Other factors associated with higher PIU includes poor mental health and poor family relationships. PA promotion programs with a gender perspective could be key to addressing PIU in adolescents.

目的:体育锻炼(PA)可能是减少青少年问题性上网(PIU)的关键。鉴于不同性别和不同年龄段的青少年使用互联网的模式和参与体育锻炼的情况会有很大不同,本研究旨在按性别和年龄分析巴塞罗那 13 至 19 岁学生中问题互联网使用与体育锻炼、心理健康和其他环境因素之间的关系:利用 2021 年 FRESC 调查的数据开展了一项横断面研究,研究对象包括巴塞罗那市的 3256 名学生。因变量为 PIU,采用经过验证的 CIUS 量表进行测量。研究采用泊松回归法估算出粗略患病率和调整患病率(PRa),并得出 95% 的置信区间(IC95%):结果:在 16 岁以上的人群中,女孩(PRa=0.62,IC95%=0.39-0.97)和男孩(PRa=0.51,IC95%=0.35-0.74)的 PIU 值较低与经常参加体育锻炼有关。16 岁以下女孩的 PIU 较低与体育活动频率较高有关(PRa=0.53,IC95%=0.31-0.88)。在所有组别中,心理健康状况不佳与较高的 PIU 有关(16 岁以下男孩,PRa=3.31,IC95%=2.42-4.51):结论:除 16 岁以下男孩外,所有群体的 PA 均与较低的 PIU 有关。与较高 PIU 相关的其他因素包括心理健康状况不佳和家庭关系不和。具有性别视角的体育锻炼促进计划可能是解决青少年 PIU 问题的关键。
{"title":"[Association of Physical Activity, Mental Health and Contextual Factors with Problematic Internet Use in Adolescents from Barcelona: A Cross-sectional Study].","authors":"Marc Olivella-Cirici, Inés Nicolao-Usechi, Esther Sánchez-Ledesma, Gemma Serral, Catrina Clotas, Xavier Continente, Katherine Pérez, Gloria Pérez","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>Physical activity (PA) may be key to reducing problematic Internet use (PIU) among adolescents. Given that Internet usage patterns and PA participation can vary significantly across genders and different age groups, this study aims to analyze the association between PIU and PA, mental health and other contextual factors, in students aged thirteen to nineteen in Barcelona, by sex and age.</p><p><strong>Methods: </strong>A cross-sectional study using data from the 2021 FRESC Survey was carried out, which included 3,256 students in the city of Barcelona. The dependent variable was PIU, measured with the validated CIUS scale. Poisson regression was used to estimate crude and adjusted prevalence ratios (PRa) with 95% confidence intervals (IC95%).</p><p><strong>Results: </strong>In the group over sixteen years old, lower PIU was associated with regular PA in girls (PRa=0.62, IC95%=0.39-0.97) and in boys (PRa=0.51, IC95%=0.35-0.74). Lower PIU in girls under sixteen was associated with higher frequency of sports activities (PRa=0.53, IC95%=0.31-0.88). Poor mental health was associated with higher PIU across all groups (boys under sixteen, PRa=3.31, IC95%=2.42-4.51).</p><p><strong>Conclusions: </strong>PA is associated with lower PIU in all groups except boys under sixteen years old. Other factors associated with higher PIU includes poor mental health and poor family relationships. PA promotion programs with a gender perspective could be key to addressing PIU in adolescents.</p>","PeriodicalId":94199,"journal":{"name":"Revista espanola de salud publica","volume":"99 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12120335/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Autumn/winter 2024-2025 seasonal vaccination programme in Spain: an end to the collapse of the healthcare system?] 西班牙2024-2025年秋冬季节疫苗接种计划:结束卫生保健系统的崩溃?]
Pub Date : 2025-03-06
Pablo Fernández-León, Juan Gómez-Salgado, Javier Fagundo-Rivera

This document aims to provide visibility and raise awareness of the vaccination campaign against influenza and COVID-19 for the 2024-2025 season in Spain. This manuscript may be of interest to the scientific community, healthcare professionals, and the general population, as it emphasizes the need for collaborative efforts among all health services and public-facing workers. Furthermore, it is important to consider that both diseases continue to pose a significant risk, especially to vulnerable populations, and vaccination is positioned as the most effective public health strategy to prevent the collapse of the healthcare system and the saturation of services.

本文件旨在提高西班牙2024-2025年流感和COVID-19疫苗接种运动的知名度和认识。这份手稿可能会引起科学界、卫生保健专业人员和一般人群的兴趣,因为它强调了所有卫生服务和面向公众的工作人员之间合作努力的必要性。此外,重要的是要考虑到这两种疾病继续构成重大风险,特别是对脆弱人群,而疫苗接种被定位为防止卫生保健系统崩溃和服务饱和的最有效的公共卫生战略。
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引用次数: 0
[Health outcomes of deprescribing proton pump inhibitors: study protocol]. [处方质子泵抑制剂的健康结果:研究方案]。
Pub Date : 2025-02-26
Amaya Echeverría Gorriti, Andrea Rodríguez Esquiroz, Patricia García González, Lorea Sanz Álvarez, Marta Marín Marín, Javier Gorricho Mendívil, Julen Fernández González, Mª Concepción Celaya Lecea, Ana Campillo Arregui, Rebeca Irisarri Garde, Javier Garjón Parra

Objective: Proton pump inhibitors (PPI) are one of the groups of drugs with the highest prevalence of use. However, in many cases they are used for the treatment of unapproved indications. For this reason, in Navarra a strategy was implemented to deprescribe PPI in those cases in which their use was not indicated. Subsequently, a project was designed in order to analyze the health outcomes of that PPI deprescription strategy.

Methods: A retrospective cohort study will be developed to evaluate health outcomes obtained after the implementation of the PPI deprescription strategy. The primary outcome will be the time until a serious adverse event, defined as one that causes hospital admission or death. We will analyze whether there are differences between patients who stopped PPI treatment and those who maintained it.

Conclusions: It is expected to obtain information on the health outcomes of the proton pump inhibitor deprescription strategy and information about the convenience of continuing it.

目的:质子泵抑制剂(PPI)是目前使用率最高的一类药物。然而,在许多情况下,它们被用于治疗未经批准的适应症。出于这个原因,在纳瓦拉实施了一项策略,在那些不需要使用PPI的病例中取消PPI的处方。随后,设计了一个项目,以分析该生产者计划取消处方战略的健康结果。方法:将开展一项回顾性队列研究,以评估实施PPI去处方策略后获得的健康结果。主要结果将是发生严重不良事件的时间,定义为导致住院或死亡的事件。我们将分析停止PPI治疗和继续使用PPI治疗的患者之间是否存在差异。结论:本研究旨在获得质子泵抑制剂减处方策略的健康结果和继续减处方的便利性信息。
{"title":"[Health outcomes of deprescribing proton pump inhibitors: study protocol].","authors":"Amaya Echeverría Gorriti, Andrea Rodríguez Esquiroz, Patricia García González, Lorea Sanz Álvarez, Marta Marín Marín, Javier Gorricho Mendívil, Julen Fernández González, Mª Concepción Celaya Lecea, Ana Campillo Arregui, Rebeca Irisarri Garde, Javier Garjón Parra","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>Proton pump inhibitors (PPI) are one of the groups of drugs with the highest prevalence of use. However, in many cases they are used for the treatment of unapproved indications. For this reason, in Navarra a strategy was implemented to deprescribe PPI in those cases in which their use was not indicated. Subsequently, a project was designed in order to analyze the health outcomes of that PPI deprescription strategy.</p><p><strong>Methods: </strong>A retrospective cohort study will be developed to evaluate health outcomes obtained after the implementation of the PPI deprescription strategy. The primary outcome will be the time until a serious adverse event, defined as one that causes hospital admission or death. We will analyze whether there are differences between patients who stopped PPI treatment and those who maintained it.</p><p><strong>Conclusions: </strong>It is expected to obtain information on the health outcomes of the proton pump inhibitor deprescription strategy and information about the convenience of continuing it.</p>","PeriodicalId":94199,"journal":{"name":"Revista espanola de salud publica","volume":"99 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12131302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143517783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Revista espanola de salud publica
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