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Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES最新文献

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Psychological risk factors for upper extremity fractures in preschool children: A case-control study. 学龄前儿童上肢骨折的心理风险因素:病例对照研究
Muhammet Zeki Gültekin, Fatih Doğar, Ahmet Sinan Sarı, Fatma Coşkun, Ahmet Yıldırım

Background: In school-age children, upper extremity fractures are associated with both parental and child-related factors and represent a multifactorial entity. This study aims to explore the psychological risk factors associated with upper extremity fractures in preschool children.

Methods: This single-center, hospital-based, age-matched case-control study involved 55 cases of upper extremity fractures and 55 controls experiencing growing pains. Parents of the children participated in face-to-face interviews. We examined the potential as-sociations between scores on the Mother-to-Infant Bonding Scale (MIBS), Adult Attention Deficit Hyperactivity Disorder Self-Report Scale (ASRS), Autism-Spectrum Quotient (AQ), State-Trait Anxiety Inventory (STAI), and Strengths and Difficulties Questionnaire (SDQ), and the risk of upper extremity fractures.

Results: Advanced parental age and lower household income emerged as risk factors for upper extremity fractures, while longer maternal educational attainment was identified as a protective factor. In the univariate analyses, elevated scores on the Autism-Spec-trum Quotient Communication subscale (AQ-C), overall AQ score, Strengths and Difficulties Questionnaire Hyperactivity subscale (SDQ-H), and Strengths and Difficulties Questionnaire Emotional and Peer Problems subscale (SDQ-Int) were associated with an increased fracture risk (Odds Ratio [OR] (95% Confidence Interval [CI]): 1.15 (1.05-1.27), OR: 1.05 (1.01-1.09), OR: 1.25 (1.01-1.54), and OR: 1.19 (1.04-1.37), respectively). The AQ-C and SDQ-Int scales remained statistically significant as risk factors for upper ex-tremity fractures (OR: 1.15 (1.02-1.28) and OR: 1.21 (1.02-1.43), respectively) in the multivariate regression analyses.

Conclusion: Our findings suggest that psychological factors affecting both parents and children could potentially increase the risk of upper extremity fractures in preschool children.

背景:在学龄儿童中,上肢骨折与父母和儿童的相关因素有关,是一个多因素的实体。本研究旨在探讨与学龄前儿童上肢骨折相关的心理风险因素:这项以医院为基础的单中心年龄匹配病例对照研究涉及 55 例上肢骨折病例和 55 例经历生长痛的对照组。儿童的父母参加了面对面的访谈。我们研究了母婴关系量表(MIBS)、成人注意缺陷多动障碍自评量表(ASRS)、自闭症谱商数(AQ)、国家特质焦虑量表(STAI)、优势与困难问卷(SDQ)的得分与上肢骨折风险之间的潜在关联:结果:父母高龄和家庭收入较低是上肢骨折的风险因素,而母亲受教育程度较高则是保护因素。在单变量分析中,自闭症特质商数沟通分量表(AQ-C)、AQ总分、优势和困难问卷多动分量表(SDQ-H)以及优势和困难问卷情感和同伴问题分量表(SDQ-Int)得分升高与骨折风险增加有关(风险比[OR](95% 置信区间[CI]):1.15(1.05-1.15)-1.15(1.05-1.15)):分别为 1.15 (1.05-1.27)、1.05 (1.01-1.09)、1.25 (1.01-1.54) 和 1.19 (1.04-1.37))。在多变量回归分析中,AQ-C和SDQ-Int量表作为上肢骨折的风险因素仍然具有统计学意义(OR:分别为1.15(1.02-1.28)和1.21(1.02-1.43)):我们的研究结果表明,影响家长和儿童的心理因素可能会增加学龄前儿童发生上肢骨折的风险。
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引用次数: 0
The role of bone turnover markers in diagnosis, monitoring, and pathological fractures of osteoporosis. 骨转换标志物在骨质疏松症的诊断、监测和病理性骨折中的作用。
Kazım Ersin Altınsoy, Beytullah Unat

Background: We investigated the utility of specific biomarkers-namely, c-terminal telopeptide (CTX), n-telopeptide (NTX), deoxypyridinoline (DPD), and tartrate-resistant acid phosphatase (TRAP)-compared to conventional diagnostic methods. We hy-pothesized that these novel biomarkers could hold substantial value in the diagnosis, treatment, and monitoring of osteoporosis.

Methods: The study was conducted over a three-year period, from January 1, 2020, to January 1, 2023. We enrolled a total of 520 patients aged 50 years or older who had been diagnosed with osteoporosis. Patients undergoing steroid treatments, which are known to contribute to osteoporosis, were excluded from the study. Additionally, we carefully selected and matched a control group consisting of 500 patients based on demographic characteristics relevant to the diagnosis of osteoporosis. This meticulous selection process resulted in a comprehensive cohort comprising 1,020 patients. Throughout the study, patients were closely monitored for a duration of one year to track the occurrence of pathological fractures and assess their overall prognosis.

Results: As a result of our rigorous investigation, we identified CTX, NTX, DPD, and TRAP as pivotal biomarkers that play a crucial role in evaluating bone health, monitoring treatment effectiveness, and detecting pathological fractures in the context of osteoporosis.

Conclusion: Our study underscores the significance of these biomarkers in advancing the diagnosis and management of osteo-porosis, offering valuable insights into the disease's progression and treatment outcomes.

背景:我们研究了特定生物标志物(即 c 端端肽(CTX)、n 端端肽(NTX)、脱氧吡啶啉(DPD)和耐酒石酸磷酸酶(TRAP))与传统诊断方法相比的效用。我们推测,这些新型生物标记物在骨质疏松症的诊断、治疗和监测方面具有重要价值:研究为期三年,从 2020 年 1 月 1 日至 2023 年 1 月 1 日。我们共招募了 520 名年龄在 50 岁或以上的骨质疏松症患者。研究排除了正在接受类固醇治疗的患者,因为众所周知类固醇会导致骨质疏松症。此外,我们还根据与骨质疏松症诊断相关的人口统计学特征,精心挑选并匹配了由 500 名患者组成的对照组。通过这一细致的筛选过程,我们建立了一个由 1,020 名患者组成的综合群组。在整个研究过程中,我们对患者进行了为期一年的密切监测,以追踪病理性骨折的发生情况并评估其总体预后:通过严格的调查,我们发现 CTX、NTX、DPD 和 TRAP 是关键的生物标志物,它们在骨质疏松症的骨健康评估、治疗效果监测和病理性骨折检测中发挥着至关重要的作用:我们的研究强调了这些生物标志物在推进骨质疏松症诊断和管理方面的重要意义,为了解疾病进展和治疗效果提供了宝贵的信息。
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引用次数: 0
Management of a large traumatic hemipelvectomy defect following a truck crush injury: a case report. 卡车挤压伤后大面积外伤性半十二指肠切除术缺损的处理:病例报告。
Mutluhan Temizsoy, Ahmet Hamdi Sakarya

This case report explores the management of a traumatic hemipelvectomy-a rare and devastating injury characterized by a high mortality rate. The patient, a 12-year-old male, suffered right lower extremity amputation and right hemipelvectomy due to a deglov-ing injury from a non-vehicle-related accident at another institution. Initially, an urgent reconstruction of the right pelvic region and suprapubic tissue defects was performed using a posterior-based fasciocutaneous flap. Following this, the patient was transferred to the pediatric intensive care unit at our hospital with a suspected diagnosis of necrotizing fasciitis. Treatment included broad spectrum antibiotics and multiple debridements to avert the onset of sepsis. Eventually, reconstruction of a 60 x 25 cm defect covering the lower back, abdomen, gluteal, and pubic regions was achieved through serial split-thickness skin grafts and a pedicled anterolateral thigh flap. The patient made a remarkable recovery, regained mobility with the aid of a walker, and was discharged in good health 22 weeks after the initial accident. This case report underscores the importance of serial debridements in preventing sepsis, the use of negative pres-sure vacuum dressing changes, the initiation of broad-spectrum antibiotics based on culture results during debridements, and prompt closure of the defect to ensure survival after traumatic hemipelvectomy. Familiarization with the principles discussed here is crucial to minimizing mortality rates and optimizing outcomes for this rare injury.

本病例报告探讨了外伤性十二指肠半切除术的治疗方法--这是一种罕见的破坏性损伤,具有死亡率高的特点。患者是一名12岁的男性,在其他医院因非车祸造成的脱臼损伤导致右下肢截肢和右侧十二指肠切除术。最初,医生使用后方筋膜皮瓣紧急重建了右骨盆区域和耻骨上组织缺损。随后,患者被转入本院儿科重症监护室,疑似诊断为坏死性筋膜炎。治疗包括广谱抗生素和多次清创,以避免败血症的发生。最后,通过连续的分层厚皮移植和大腿前外侧皮瓣重建了 60 x 25 厘米的缺损,覆盖了下背部、腹部、臀部和耻骨区。患者康复效果显著,在助行器的帮助下恢复了行动能力,并在最初事故发生 22 周后健康出院。本病例报告强调了连续清创对于预防败血症、使用负压真空换药、根据清创过程中的培养结果使用广谱抗生素以及及时关闭缺损以确保外伤性十二指肠切除术后患者存活的重要性。熟悉本文讨论的原则对于最大限度地降低这种罕见损伤的死亡率和优化治疗效果至关重要。
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引用次数: 0
Effects of ketamine on penile tissues in an experimental priapism model in rats. 氯胺酮对实验性勃起功能障碍模型大鼠阴茎组织的影响
Vildan Kölükçü, Mehtap Gürler Balta, Hakan Tapar, Tugba Karaman, Serkan Karaman, Velid Unsal, Fikret Gevrek, Kenan Yalçın, Fatih Fırat

Background: This study aimed to evaluate the histopathological and biochemical effects of ketamine on penile tissues following ischemia-reperfusion injury induced by priapism.

Methods: Twenty-four male rats were randomized into three groups. Group 1 served as the control group. Group 2 underwent the priapism model to induce ischemia-reperfusion injury. Group 3, the treatment group, experienced a similar ischemia-reperfusion model as Group 2; additionally, 50 mg/kg of ketamine was administered intraperitoneally just before reperfusion. Blood biochemical analyses and penile histopathological evaluations were performed.

Results: In Group 3, significant improvements were observed in all histopathological scores, including desquamation, edema, inflammation, and vasocongestion compared to Group 2 (p<0.001). Blood biochemical analyses showed that the malondialdehyde (MDA) levels were recorded as 10 in Group 2, with a significant decrease in Group 3 (p=0.013). Similarly, proinflammatory cytokine levels, including interleukin-1 beta (IL-1β), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α), were found to be suppressed in Group 3 compared to Group 2 (p=0.003, p=0.022, and p=0.028, respectively). Antioxidant enzyme activities, such as glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD), were higher in Group 3 compared to Group 2 (p=0.016 and p=0.024, respec-tively).

Conclusion: Ketamine is an effective anesthetic agent in alleviating the effects of penile ischemia-reperfusion injury.

背景:本研究旨在评估氯胺酮对阴茎缺血再灌注损伤后的组织病理学和生物化学影响:本研究旨在评估氯胺酮对阴茎组织缺血再灌注损伤后的组织病理学和生物化学影响:将 24 只雄性大鼠随机分为三组。第一组为对照组。方法:24 只雄性大鼠随机分为三组,第 1 组为对照组,第 2 组为治疗组。第3组为治疗组,与第2组经历类似的缺血再灌注模型;此外,在再灌注前腹腔注射50毫克/千克氯胺酮。实验组进行了血液生化分析和阴茎组织病理学评估:结果:与第 2 组相比,第 3 组的所有组织病理学评分均有明显改善,包括脱屑、水肿、炎症和血管充血(p):氯胺酮是一种有效的麻醉剂,可减轻阴茎缺血再灌注损伤的影响。
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引用次数: 0
Effect of pre-incisional and peritoneal local anesthetics administration on colon anastomosis and wound healing. 切口前和腹膜局部麻醉对结肠吻合术和伤口愈合的影响
Uğur Kesici, Yahya Kaan Karatepe, Ahmet Furkan Mazlum, Kubra Bozali, Mahmut Salih Genç, Leman Damla Ercan, Mehmet Güray Duman, Ayşe Gökçen Sade, Eray Metin Guler, Sevgi Kesici

Background: Previous research has shown that levobupivacaine is as effective as bupivacaine but carries a lower risk of cardiac and central nervous system toxicity. This study explores whether levobupivacaine and bupivacaine are preferable for all patients, includ-ing those with comorbidities, particularly focusing on their effects on colonic anastomosis. The primary objective is to examine the influence of levobupivacaine and bupivacaine on colonic anastomosis. Additionally, the study will assess their impact on wound healing and their anti-adhesive properties.

Methods: Conducted between July 28, 2022, to August 4, 2022, at the Hamidiye Animal Experiments Laboratory, this study was approved by the University Science Health, Hamidiye Animal Experiments Local Ethics Committee. This study was conducted using 21 male Sprague rats aged 16-20 weeks. The rats were allocated into three equal groups of seven each: Group C: pre-incisional isotonic; Group B: pre-incisional bupivacaine; and Group L: pre-incisional levobupivacaine. Macroscopic adhesion scores (MAS) were recorded during laparotomy and tissue samples were taken for histopathological examination and hydroxyproline levels measurement. Wound tensile strength along the middle incision line and anastomotic burst pressure were also assessed.

Results: MAS was statistically significantly lower in Groups B and L compared to Group C (p<0.001). The wound histopathology score (WHS) was significantly higher in Group L than in Group B (p=0.021). Colon histopathology scores (CHSs) were also signifi-cantly higher in Group L compared to Group C (p=0.011).

Conclusion: TThe study found that bupivacaine and levobupivacaine did not significantly enhance wound healing, although le-vobupivacaine significantly improved WHS relative to bupivacaine. According to the findings of this study, levobupivacaine can enhance clinical practice by being used in patients undergoing colon anastomosis. It contributes significantly to the durability of colon anasto-mosis, has a more positive effect on wound healing compared to bupivacaine, and exhibits anti-adhesive properties. Additional clinical trials are necessary to validate these results further.

背景:以前的研究表明,左旋布比卡因与布比卡因一样有效,但心脏和中枢神经系统毒性风险较低。本研究探讨了左旋布比卡因和布比卡因是否更适合所有患者,包括合并症患者,尤其关注它们对结肠吻合术的影响。研究的主要目的是探讨左布比卡因和布比卡因对结肠吻合术的影响。此外,研究还将评估它们对伤口愈合的影响及其抗粘连特性:本研究于 2022 年 7 月 28 日至 2022 年 8 月 4 日在哈米迪耶动物实验实验室进行,并获得了哈米迪耶大学科学卫生部动物实验地方伦理委员会的批准。本研究使用了 21 只年龄为 16-20 周的雄性 Sprague 大鼠。大鼠被平均分为三组,每组七只:C组:切口前等渗组;B组:切口前布比卡因组;L组:切口前左布比卡因组。在开腹手术中记录宏观粘连评分(MAS),并采集组织样本进行组织病理学检查和羟脯氨酸水平测定。此外,还评估了沿中间切口线的伤口抗张强度和吻合口破裂压力:结果:与 C 组相比,B 组和 L 组的 MAS 在统计学上明显较低(p):研究发现,布比卡因和左旋布比卡因并不能明显促进伤口愈合,但左旋布比卡因相对于布比卡因能明显改善伤口愈合率。根据这项研究的结果,左旋布比卡因可用于结肠吻合术患者,从而改善临床实践。与布比卡因相比,左旋布比卡因能大大提高结肠吻合术的耐久性,对伤口愈合有更积极的作用,并具有抗粘连特性。要进一步验证这些结果,还需要进行更多的临床试验。
{"title":"Effect of pre-incisional and peritoneal local anesthetics administration on colon anastomosis and wound healing.","authors":"Uğur Kesici, Yahya Kaan Karatepe, Ahmet Furkan Mazlum, Kubra Bozali, Mahmut Salih Genç, Leman Damla Ercan, Mehmet Güray Duman, Ayşe Gökçen Sade, Eray Metin Guler, Sevgi Kesici","doi":"10.14744/tjtes.2024.39551","DOIUrl":"10.14744/tjtes.2024.39551","url":null,"abstract":"<p><strong>Background: </strong>Previous research has shown that levobupivacaine is as effective as bupivacaine but carries a lower risk of cardiac and central nervous system toxicity. This study explores whether levobupivacaine and bupivacaine are preferable for all patients, includ-ing those with comorbidities, particularly focusing on their effects on colonic anastomosis. The primary objective is to examine the influence of levobupivacaine and bupivacaine on colonic anastomosis. Additionally, the study will assess their impact on wound healing and their anti-adhesive properties.</p><p><strong>Methods: </strong>Conducted between July 28, 2022, to August 4, 2022, at the Hamidiye Animal Experiments Laboratory, this study was approved by the University Science Health, Hamidiye Animal Experiments Local Ethics Committee. This study was conducted using 21 male Sprague rats aged 16-20 weeks. The rats were allocated into three equal groups of seven each: Group C: pre-incisional isotonic; Group B: pre-incisional bupivacaine; and Group L: pre-incisional levobupivacaine. Macroscopic adhesion scores (MAS) were recorded during laparotomy and tissue samples were taken for histopathological examination and hydroxyproline levels measurement. Wound tensile strength along the middle incision line and anastomotic burst pressure were also assessed.</p><p><strong>Results: </strong>MAS was statistically significantly lower in Groups B and L compared to Group C (p<0.001). The wound histopathology score (WHS) was significantly higher in Group L than in Group B (p=0.021). Colon histopathology scores (CHSs) were also signifi-cantly higher in Group L compared to Group C (p=0.011).</p><p><strong>Conclusion: </strong>TThe study found that bupivacaine and levobupivacaine did not significantly enhance wound healing, although le-vobupivacaine significantly improved WHS relative to bupivacaine. According to the findings of this study, levobupivacaine can enhance clinical practice by being used in patients undergoing colon anastomosis. It contributes significantly to the durability of colon anasto-mosis, has a more positive effect on wound healing compared to bupivacaine, and exhibits anti-adhesive properties. Additional clinical trials are necessary to validate these results further.</p>","PeriodicalId":94263,"journal":{"name":"Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES","volume":"30 5","pages":"316-322"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11154069/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140913577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical analysis of transverse process fractures: A comprehensive study on patient characteristics, management, and outcomes in trauma care. 横突骨折的临床分析:关于创伤护理中患者特征、管理和结果的综合研究。
Göksal Günerhan, Afşin Emre Akpınar, Emin Çağıl

Background: Transverse process fractures (TPFs) are commonly encountered in trauma patients and are often associated with polytrauma. While traditionally considered stable injuries, recent research suggests their significance in spinal trauma may be under-estimated. This study aims to provide insights into the management and outcomes of TPFs, evaluating their predictive potential for identifying clinically significant spinal fractures and associated injuries.

Methods: A retrospective review of trauma registry data from a Level I trauma center was conducted, encompassing patients with TPFs from September 2022 to September 2023. Inclusion criteria involved patients aged 18 or older with confirmed TPFs via com-puted tomography (CT) and magnetic resonance imaging (MRI), managed nonoperatively. Data on demographics, injury mechanisms, associated injuries, pain management, and treatment outcomes were analyzed. Pain severity and functionality were assessed using the Visual Analog Scale (VAS) and the Oswestry Disability Index (ODI).

Results: A total of 190 patients, predominantly male (129 patients, 67.9%), with a mean age of 45.7 years, were included in the study. Motor vehicle accidents (MVA) were the leading cause of admission (44.7%). Thoracic injuries were the most common associ-ated pathology. Of the study cohort, 88 patients (46.3%) presented with single-level TPFs, while 102 patients (53.7%) had multilevel fractures. Analysis revealed distinct differences between these groups, with multilevel TPF patients exhibiting a higher frequency of associated injuries and a notable proportion requiring hospitalization or surgical intervention. Multilevel TPF patients exhibited higher initial pain and disability scores compared to single-level TPF patients. Both groups showed significant reductions in VAS and ODI scores at the 3-month follow-up.

Conclusion: TPFs, previously considered minor injuries, demonstrate significant pain and functional limitations. They often accompany systemic pathologies, particularly in multilevel fractures, necessitating a multidisciplinary approach to management. The "Protection, Rest, Ice, Compression, Elevation" (PRICE) approach, including Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and muscle relaxants, along with collar or brace support when necessary, proves effective in pain management and functional improvement. These findings emphasize the importance of recognizing TPFs as complex injuries requiring tailored management strategies. Further research and collaboration among healthcare providers are warranted to refine treatment approaches and optimize outcomes for patients with TPFs.

背景:横突骨折(TPFs)在创伤患者中很常见,而且往往与多发性创伤有关。虽然横突骨折传统上被认为是稳定型损伤,但最近的研究表明其在脊柱创伤中的重要性可能被低估了。本研究旨在深入了解 TPFs 的管理和结果,评估其在识别具有临床意义的脊柱骨折和相关损伤方面的预测潜力:对一家一级创伤中心的创伤登记数据进行了回顾性分析,涵盖了 2022 年 9 月至 2023 年 9 月期间的 TPF 患者。纳入标准包括经计算机断层扫描(CT)和核磁共振成像(MRI)证实为TPF的18岁或18岁以上非手术治疗患者。对有关人口统计学、损伤机制、相关损伤、疼痛管理和治疗效果的数据进行了分析。采用视觉模拟量表(VAS)和奥斯韦斯特里残疾指数(ODI)对疼痛严重程度和功能进行评估:共有 190 名患者参与了研究,其中男性居多(129 人,占 67.9%),平均年龄为 45.7 岁。机动车事故(MVA)是入院的主要原因(44.7%)。胸腔损伤是最常见的相关病理。在研究队列中,88 名患者(46.3%)为单层 TPF,102 名患者(53.7%)为多层骨折。分析表明,这两组患者之间存在明显差异,多层次 TPF 患者伴发损伤的频率更高,需要住院或手术治疗的比例也明显更高。与单层 TPF 患者相比,多层 TPF 患者的初始疼痛和残疾评分更高。在3个月的随访中,两组患者的VAS和ODI评分均有明显下降:结论:以往被认为是轻微损伤的 TPF 显示出明显的疼痛和功能限制。结论:TPF 以前被认为是轻微损伤,但会造成严重的疼痛和功能限制,通常会伴随全身性病变,尤其是多层次骨折,因此有必要采用多学科方法进行治疗。保护、休息、冰敷、加压、抬高"(PRICE)方法,包括非甾体抗炎药(NSAIDs)和肌肉松弛剂,以及必要时的项圈或支架支撑,在疼痛控制和功能改善方面证明是有效的。这些研究结果强调了将 TPF 视为复杂损伤的重要性,需要采取量身定制的管理策略。有必要在医疗服务提供者之间开展进一步的研究和合作,以完善治疗方法并优化 TPFs 患者的治疗效果。
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引用次数: 0
Bone grafting combined with a spiral flap technique for the reconstruction of fingertip amputations. 植骨结合螺旋皮瓣技术重建指尖截肢。
Fatih Ceran, Mehmet Bozkurt, Salih Onur Basat, Emin Kapi

Background: Various reconstructive options exist for distal finger and pulp defects, including grafting and local or distant flaps. In addition to reconstructing the normal anatomical structure, preserving the sensory function of the finger is crucial. This study presents the results of using bone grafting combined with a spiral flap (BGcSF) technique for reconstructing pulp defects accompanied by bone loss.

Methods: Twenty-three patients with fingertip defects were treated using the BGcSF technique. Flap sensitivity was assessed us-ing the Semmes-Weinstein monofilament (SWM) and static two-point discrimination (2PD) tests at six months postoperatively. Cold intolerance of the affected fingers was evaluated using the Cold Intolerance Severity Score (CISS) questionnaire at one year postop-eratively. Patient satisfaction was assessed using the Michigan Hand Outcomes Questionnaire (MHQ). Range of motion (ROM) for the proximal and distal interphalangeal joints was measured with a goniometer at one year postoperatively.

Results: Distal flap necrosis, affecting 10-15% of the flap area, was observed in one patient. No other complications were noted. The mean static two-point discrimination value at six months postoperatively was 5.6 mm, and the mean SWM score was 3.56. The mean CISS score at one year postoperatively was 18.8. The mean active ROM angle for the proximal interphalangeal joint was 106.7 degrees, and for the distal interphalangeal joint, it was 65.4 degrees. The mean MHQ score at one year postoperatively was 18.5.

Conclusion: The BGcSF technique provides soft tissue with a texture similar to that of the fingertips and supports effective sensory repair. It can be considered a viable option for fingertip reconstruction in cases where replantation is not feasible.

背景:针对手指远端和牙髓缺损有多种重建方案,包括移植和局部或远端皮瓣。除了重建正常的解剖结构外,保留手指的感觉功能也至关重要。本研究介绍了使用植骨结合螺旋皮瓣(BGcSF)技术重建伴有骨质流失的牙髓缺损的结果:方法:采用 BGcSF 技术治疗了 23 名指尖缺损患者。术后六个月,使用塞姆斯-韦恩斯坦单丝(SWM)和静态两点辨别(2PD)测试评估了皮瓣敏感性。术后一年时,使用不耐寒严重程度评分(CISS)问卷评估患指的不耐寒程度。患者满意度采用密歇根手部结果问卷(MHQ)进行评估。术后一年,用测角器测量近端和远端指间关节的活动范围(ROM):结果:观察到一名患者的远端皮瓣坏死,影响皮瓣面积的10-15%。未发现其他并发症。术后六个月的平均静态两点辨别值为 5.6 mm,平均 SWM 得分为 3.56。术后一年的平均CISS评分为18.8分。近端指间关节的平均主动 ROM 角度为 106.7 度,远端指间关节的平均主动 ROM 角度为 65.4 度。术后一年的平均MHQ评分为18.5分:结论:BGcSF 技术可提供与指尖质地相似的软组织,并支持有效的感觉修复。结论:BGcSF 技术可提供质地与指尖相似的软组织,并支持有效的感觉修复,在无法进行再植的情况下,它可被视为指尖重建的可行方案。
{"title":"Bone grafting combined with a spiral flap technique for the reconstruction of fingertip amputations.","authors":"Fatih Ceran, Mehmet Bozkurt, Salih Onur Basat, Emin Kapi","doi":"10.14744/tjtes.2023.05118","DOIUrl":"10.14744/tjtes.2023.05118","url":null,"abstract":"<p><strong>Background: </strong>Various reconstructive options exist for distal finger and pulp defects, including grafting and local or distant flaps. In addition to reconstructing the normal anatomical structure, preserving the sensory function of the finger is crucial. This study presents the results of using bone grafting combined with a spiral flap (BGcSF) technique for reconstructing pulp defects accompanied by bone loss.</p><p><strong>Methods: </strong>Twenty-three patients with fingertip defects were treated using the BGcSF technique. Flap sensitivity was assessed us-ing the Semmes-Weinstein monofilament (SWM) and static two-point discrimination (2PD) tests at six months postoperatively. Cold intolerance of the affected fingers was evaluated using the Cold Intolerance Severity Score (CISS) questionnaire at one year postop-eratively. Patient satisfaction was assessed using the Michigan Hand Outcomes Questionnaire (MHQ). Range of motion (ROM) for the proximal and distal interphalangeal joints was measured with a goniometer at one year postoperatively.</p><p><strong>Results: </strong>Distal flap necrosis, affecting 10-15% of the flap area, was observed in one patient. No other complications were noted. The mean static two-point discrimination value at six months postoperatively was 5.6 mm, and the mean SWM score was 3.56. The mean CISS score at one year postoperatively was 18.8. The mean active ROM angle for the proximal interphalangeal joint was 106.7 degrees, and for the distal interphalangeal joint, it was 65.4 degrees. The mean MHQ score at one year postoperatively was 18.5.</p><p><strong>Conclusion: </strong>The BGcSF technique provides soft tissue with a texture similar to that of the fingertips and supports effective sensory repair. It can be considered a viable option for fingertip reconstruction in cases where replantation is not feasible.</p>","PeriodicalId":94263,"journal":{"name":"Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES","volume":"30 5","pages":"337-342"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11154071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140913622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronic jejuno-colonic fistula and intestinal malabsorption due to multiple magnet ingestions: A case report and systematic review. 多次摄入磁铁导致慢性空肠结肠瘘和肠道吸收不良:病例报告和系统综述。
Rahşan Özcan, Ali Ekber Hakalmaz, Ayşe Kalyoncu Uçar, Omer Beser, Senol Emre

Magnet ingestion in children can lead to serious complications, both acutely and chronically. This case report discusses the treatment approach for a case involving multiple magnet ingestions, which resulted in a jejuno-colonic fistula, segmental intestinal volvulus, hepa-tosteatosis, and renal calculus detected at a late stage. Additionally, we conducted a literature review to explore the characteristics of intestinal fistulas caused by magnet ingestion. A six-year-old girl was admitted to the Pediatric Gastroenterology Department pre-senting with intermittent abdominal pain, vomiting, and diarrhea persisting for two years. Initial differential diagnoses included celiac disease, cystic fibrosis, inflammatory bowel disease, and tuberculosis, yet the etiology remained elusive. The Pediatric Surgery team was consulted after a jejuno-colonic fistula was suspected based on magnetic resonance imaging findings. The physical examination revealed no signs of acute abdomen but showed mild abdominal distension. Subsequent upper gastrointestinal series and contrast enema graphy confirmed a jejuno-colonic fistula and segmental volvulus. The family later reported that the child had swallowed a magnet two years prior, and medical follow-up had stopped after the spontaneous expulsion of the magnets within one to two weeks. Surgical intervention was necessary to correct the volvulus and repair the large jejuno-colonic fistula. To identify relevant studies, we conducted a detailed literature search on magnet ingestion and gastrointestinal fistulas according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. We identified 44 articles encompassing 55 cases where symptoms did not manifest in the acute phase and acute abdomen was not observed. In 29 cases, the time of magnet ingestion was unknown. Among the 26 cases with a known ingestion time, the average duration until fistula detection was 22.8 days (range: 1-90 days). Fistula repairs were performed via laparotomy in 47 cases.

儿童误食磁铁可导致严重的急性和慢性并发症。本病例报告讨论了一个涉及多次摄入磁铁的病例的治疗方法,该病例导致了空肠结肠瘘、节段性肠外翻、肝骨质增生和晚期发现的肾结石。此外,我们还进行了文献综述,以探讨误食磁铁导致肠瘘的特点。一名六岁女童因持续两年的间歇性腹痛、呕吐和腹泻而被送往儿科消化内科就诊。最初的鉴别诊断包括乳糜泻、囊性纤维化、炎症性肠病和结核病,但病因仍然难以确定。小儿外科团队根据磁共振成像结果,怀疑患者患有空肠结肠瘘。体格检查未发现急腹症体征,但有轻度腹胀。随后的上消化道造影和造影剂灌肠检查证实患儿患有空肠结肠瘘和节段性肠管外翻。家属后来报告说,孩子两年前曾吞下一块磁铁,磁铁在一到两周内自发排出后,医疗随访就停止了。必须进行手术治疗,以纠正空肠卷曲并修复巨大的空肠结肠瘘。为了确定相关研究,我们根据 PRISMA(系统综述和元分析首选报告项目)指南对磁铁摄入和胃肠道瘘进行了详细的文献检索。我们共发现 44 篇文章,涵盖 55 个病例,这些病例在急性期症状不明显,也未观察到急腹症。29 个病例的磁铁摄入时间不明。在已知摄入时间的 26 个病例中,发现瘘管的平均时间为 22.8 天(范围:1-90 天)。47例患者通过开腹手术进行了瘘管修补。
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引用次数: 0
Determinants of 30-day mortality in elderly patients admitted to a cardiovascular surgery intensive care unit. 心血管外科重症监护室收治的老年患者 30 天死亡率的决定因素。
Bedih Balkan, Zahide Özlem Ulubay, Elif Güneysu, Ahmet Said Dündar, Engin Ihsan Turan

Background: This study aims to identify the factors influencing 30-day morbidity and mortality in patients aged 65 and older undergoing cardiovascular surgery.

Methods: Data from 360 patients who underwent cardiac surgery between January 2012 and August 2021 in the Cardiovascular Surgery Intensive Care Unit (CVS ICU) were analyzed. Patients were categorized into two groups: "mortality+" (33 patients) and "mortality-" (327 patients). Factors influencing mortality, including preoperative, intraoperative, and postoperative risk factors, complications, and outcomes, were assessed.

Results: Significant differences were observed between the two groups in factors affecting mortality, including extubation time, ICU stay duration, blood transfusion, surgical reexploration, aortic clamp duration, glomerular filtration rate (GFR), blood urea nitrogen (BUN), creatinine, hemoglobin A1c (HbA1c) levels, and the lowest systolic blood pressure during the first 24 hours in the ICU (p<0.05). The "mortality+" group had longer extubation times and ICU stays, required more blood transfusions, and had higher BUN-creatinine ratios, but lower systolic blood pressures, GFR, and HbA1c levels. Mortality was also higher in patients needing noradrenaline infusions and those who underwent reoperation for bleeding (p<0.05).

Conclusion: By optimizing preoperative renal function, minimizing extubation time, shortening ICU stays, and carefully managing blood transfusions, surgical reexplorations, aortic clamp duration, and HbA1c levels, we believe that the mortality rate can be reduced in elderly patients. Key strategies include shortening aortic clamp times, reducing perioperative blood transfusions, and ensuring effective bleeding control.

背景:本研究旨在确定影响接受心血管手术的 65 岁以上患者 30 天发病率和死亡率的因素:本研究旨在确定影响接受心血管手术的 65 岁及以上患者 30 天发病率和死亡率的因素:分析了 2012 年 1 月至 2021 年 8 月期间在心血管外科重症监护室(CVS ICU)接受心脏手术的 360 名患者的数据。患者被分为两组:"死亡率+"组(33 例)和 "死亡率-"组(327 例)。评估了影响死亡率的因素,包括术前、术中和术后风险因素、并发症和结果:结果:两组患者在影响死亡率的因素方面存在显著差异,包括拔管时间、重症监护室住院时间、输血、手术再次切除、主动脉夹持时间、肾小球滤过率(GFR)、血尿素氮(BUN)、肌酐、血红蛋白 A1c(HbA1c)水平以及重症监护室最初 24 小时内的最低收缩压(p):我们认为,通过优化术前肾功能、尽量缩短拔管时间、缩短重症监护室停留时间,以及谨慎管理输血、手术再探查、主动脉夹钳持续时间和 HbA1c 水平,可以降低老年患者的死亡率。主要策略包括缩短主动脉夹钳时间、减少围手术期输血和确保有效控制出血。
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引用次数: 0
The role of ischemia-modified albumin, presepsin, delta neutrophil index, and inflammatory markers in diagnosing acute cholecystitis. 缺血修饰白蛋白、前蛋白、δ中性粒细胞指数和炎症标志物在诊断急性胆囊炎中的作用。
M. Gedik, Ali İhsan Kilci, Hakan Hakkoymaz, Muhammed Seyithanoğlu, Muhammed Alperen Orakçı, Nuri Mehmet Basan, Arif Aksu, Ömer Faruk Küçük
BACKGROUNDThe purpose of this study is to determine the significance of markers such as C-reactive protein, procalcitonin, complete blood count parameters, delta neutrophil index, ischemia-modified albumin, presepsin, and oxidative stress indicators, which are associated with inflammation, oxidative stress, and ischemia in the pathology and diagnosis of acute cholecystitis in adults.METHODSPatients diagnosed with acute cholecystitis in the emergency department and healthy individuals in the control group were included in the study. Routine blood count and biochemistry analyses were performed on the participants. Blood serum was used to measure ischemia-modified albumin, presepsin, and oxidative stress indicators.RESULTSWhite blood cell count, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, delta neutrophil index, C-reactive protein, procalcitonin, ischemia-modified albumin, ischemia-modified albumin to albumin ratio, presepsin, and oxidative stress indicators were significantly higher in patients with cholecystitis compared to the control group. Measurements of white blood cell count, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and delta neutrophil index can be included as part of the complete blood count. The complete blood count parameters are readily available and do not incur additional costs to the healthcare system.CONCLUSIONThe authors believe that the neutrophil-to-lymphocyte ratio, delta neutrophil index, ischemia-modified albumin, ischemia-modified albumin to albumin ratio, and presepsin values can be used as new markers in the diagnosis of acute cholecystitis due to their high sensitivity, specificity, and low negative likelihood ratio.
背景本研究的目的是确定 C 反应蛋白、降钙素原、全血细胞计数参数、δ中性粒细胞指数、缺血修饰白蛋白、前蛋白和氧化应激指标等与炎症、氧化应激和缺血相关的指标在成人急性胆囊炎的病理诊断中的意义。对参与者进行常规血细胞计数和生化分析。结果与对照组相比,胆囊炎患者的白细胞计数、中性粒细胞与淋巴细胞比率、血小板与淋巴细胞比率、δ中性粒细胞指数、C反应蛋白、降钙素原、缺血修饰白蛋白、缺血修饰白蛋白与白蛋白比率、降钙素原和氧化应激指标均显著升高。白细胞计数、中性粒细胞与淋巴细胞比率、血小板与淋巴细胞比率和δ中性粒细胞指数的测量可作为全血细胞计数的一部分。作者认为,中性粒细胞与淋巴细胞比值、δ中性粒细胞指数、缺血修饰白蛋白、缺血修饰白蛋白与白蛋白比值和前蛋白值因其高灵敏度、高特异性和低阴性似然比,可作为诊断急性胆囊炎的新标记物。
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引用次数: 0
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Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES
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