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Evaluation of Sodium Benzoate as a Preservative in Apple Juice after Different Periods of Storage in Sunlight on rats’ 大鼠日光下不同贮存期苹果汁中苯甲酸钠防腐剂的评价
Pub Date : 2020-12-20 DOI: 10.21608/bnni.2020.215691
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引用次数: 0
Protective Effect of Nettle and Olive Leaves on Hyperlipidemia in Experimental Rats 荨麻、橄榄叶对实验大鼠高脂血症的保护作用
Pub Date : 2020-12-12 DOI: 10.21608/bnni.2020.190313
Aya Mohamed Anies, S. Saad, S. Ibraheim
yslipidemia is a major contributor to atherosclerotic cardiovascular disease. Recently, World Health Organization (WHO) reported that cardiovascular diseases (CVD) account for 46% of ever all mortality in Egypt. So that; the present study investigated, the protective effect of nettle and olive leaves on hyperlipidemia in experimental rats. Thirty six male albino rats weighing 130 ± 20 g used in this study and divided into equal six groups ( 6 rats each),the first kept as anegative control group (-ve) received basal diet throughout the experiment period, while the second was the (+ve) control group which fed on hyperlipidemic diet for four weeks, while the four others groups given hyperlipidemic diet supplemented with nettle leaves (5%) ,( 10 %) and olive leaves(5 %), (10%) respectively for four weeks (astreatment groups ) .The chemical composition and phenolic compounds of both leaves were done . At the end of the experiment, biological data were calculated; blood samples were taken to biochemical analysis. In addition, histopathological examination was done. The results revealed that hyperlipidemic diet in the (+ve) control group increased body weight gain ,relative organ weight, serum lipid profile, Malondialdhyde (MDA), liver enzymes and serum glucose, decreased in serum HDL-C, serum Superoxide Dismutase (SOD), and Glutathione Peroxidase (GPx) . All treated groups with two leaves showed improvement previously parameters compared with positive control group. In conclusion, the consumption of nettle and olive leaves could be used for improving lipid profile, liver function and protect from hyperlipidemia in experimental rats.
血脂异常是动脉粥样硬化性心血管疾病的主要诱因。最近,世界卫生组织(世卫组织)报告说,心血管疾病(CVD)占埃及所有死亡率的46%。所以,;本研究探讨了荨麻叶和橄榄叶对实验大鼠高脂血症的保护作用。本研究选用体重130±20 g的雄性白化大鼠36只,分为6组,每组6只,第一组为阴性对照组(-ve),在实验期间饲喂基础饲粮,第二组为(+ve)对照组,连续四周饲喂高脂血症饲粮,其余4组在高脂血症饲粮中添加荨麻叶(5%)、荨麻叶(10%)和橄榄叶(5%)。(10%)分别处理4周(处理组),测定两叶的化学成分和酚类化合物含量。实验结束时,计算生物学数据;血样被带去做生化分析。并行组织病理学检查。结果表明,(+ve)对照组高脂血症饮食增加了大鼠的体重、相对脏器重量、血脂、丙二醛(MDA)、肝酶和血清葡萄糖,降低了血清HDL-C、血清超氧化物歧化酶(SOD)和谷胱甘肽过氧化物酶(GPx)。两叶处理组与阳性对照组相比,上述参数均有改善。综上所述,食用荨麻叶和橄榄叶可改善实验大鼠血脂,改善肝功能,预防高脂血症。
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引用次数: 0
Conceivable Effect of feeding Crackers Containing Peas and Tangerine Peels on Rats with diabetes induced by alloxan 四氧嘧啶致糖尿病大鼠喂含豌豆和陈皮饼干的可能影响
Pub Date : 2020-12-01 DOI: 10.21608/BNNI.2020.172492
hanan shalaby, H. El-sayed
V egetable and fruit peels are commonly rich in phenolic with antioxidant properties so it considered metabolic syndrome remedies. This study was evaluated the phenolic compounds of peas and tangerinepeels powder may as beneficial health on diabetic rats were fed on crackers enrich with 10% from its.  The chemical compositionof crackers was determined. Thirty healthy adult male albino rats were separated into five groups (six rats each) as follows: Group (1) were fed on basal diet as negative control. Other groups were injected subcutaneous with Alloxan (150 mg/kg body weight) to induce diabetes. Group (2), received the normal diet as a positive control, Group (3) intake standard diet and crackers without peels. Groups (4 and 5)fed on natural diet and cracker with 10% peas and tangerine peels respectively for 8 weeks. In addition, glucose, lipid profile, liver and kidney functions were determined in serum and examination tissues were carried out. Results obtained that tangerine peels had the highest antioxidant activity and phenolic compounds. Pea’s peels were the highest value of protein and fiber while fat and moisture contents is the lowest. Enrichment of crackerswith 10% tangerine and pea’s peels caused increases in sensory evaluation. Cracker with tangerine and peas peels showed improve glucose, serum lipid profile, liver, kidney functions.  Pancreas tissues of groups (4, 5) were ameliorate compare with group (3). Thus, the study imagery those crackers containing 10% peas and tangerine peels exhibit high potential to enhance the nutritional value and protection against diabetes diseases.
蔬菜和水果果皮通常含有丰富的酚类物质,具有抗氧化特性,因此被认为是代谢综合征的治疗方法。本研究评价了豌豆陈皮粉中酚类化合物对糖尿病大鼠的健康作用。测定了裂解物的化学成分。选取健康成年雄性白化大鼠30只,随机分为5组(每组6只):1组以基础饲粮为阴性对照。其余各组皮下注射四氧嘧啶(150 mg/kg体重)诱导糖尿病。对照组(2)以正常饮食为阳性对照,对照组(3)以标准饮食和无皮饼干为阳性对照。4组和5组分别饲喂天然日粮和添加10%豌豆皮和陈皮的饼干,为期8周。此外,测定血清中葡萄糖、血脂、肝肾功能及检查组织。结果表明,陈皮具有最高的抗氧化活性和酚类化合物。豌豆皮的蛋白质和纤维含量最高,脂肪和水分含量最低。在饼干中加入10%的橘子皮和豌豆皮可以提高感官评价。陈皮、豌豆皮夹心饼能改善血糖、血脂、肝肾功能。与组(3)相比,组(4,5)的胰腺组织得到改善。因此,研究表明,含有10%豌豆和陈皮的饼干具有很高的提高营养价值和预防糖尿病疾病的潜力。
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引用次数: 0
Potential Protective Effects of Ganoderma lucidum Powder against Carbon Tetrachloride Induced Liver Disorders in rats: Biological, Biochemical and Immunological Studies 灵芝粉对四氯化碳所致大鼠肝脏疾病的潜在保护作用:生物学、生化和免疫学研究
Pub Date : 2020-12-01 DOI: 10.21608/bnni.2020.196206
Sara Sayed Ahmed, Nahed Abd Elalal, Y. Elhassaneen
: iver is the main organ in the body for intense metabolism and excretion. A large number of chemicals and medicines/drugs used routinely in daily lives can cause disorders and possibly liver disease. The aim of exploring some aspects related to the potential hepatoprotective activity of Ganoderma lucidum versus carbon tetrachloride (CCl 4 ) intoxication in rat liver. When compared with the normal group rats, the CCl 4 treated rats showed significant (p≤0.05) decreased in different biological parameters. Also, biochemical parameters such liver enzymes activities were significant (p≤0.05) elevation when compared with the normal group rats. For immunological parameters, Alb was significant (p≤0.05) decreased by the rate of -29.44 and TNF-α increased by 93.28%. This also coincided with an imbalance in the oxidants/antioxidants status in the blood, which was represented by a decrease in the level of antioxidants and a high level of oxidants. All of those parameters were indicating the liver injury by CCl 4 . Whereas animal treated/fed with Ganoderma lucidum powder (GLP) showed significant (p≤0.05) improvements in all previous status biomarkers indicating the protection against hepatic cell damage. A positive dose - response was recorded between the concentrations of GLP applied and the level of improvement noticed in all measured markers. In conclusion, GLP was effective in protecting against CCl 4 -induced liver disorders. Present study recommended like of that algae powder by a concentrations up to 5% (w/w), amount to be included in daily diets, drinks and food supplementation after trial study on volunteer human.
肝脏是人体进行剧烈代谢和排泄的主要器官。日常生活中经常使用的大量化学品和药物可引起紊乱,甚至可能引起肝脏疾病。目的探讨灵芝对大鼠肝脏四氯化碳中毒的保护作用。与正常组大鼠比较,ccl4处理大鼠各生物学指标均有显著性(p≤0.05)降低。肝酶活性等生化指标均较正常组显著(p≤0.05)升高。免疫指标方面,Alb显著(p≤0.05)降低(-29.44),TNF-α显著升高(93.28%)。这也与血液中氧化剂/抗氧化剂状态的不平衡相吻合,表现为抗氧化剂水平的降低和氧化剂水平的升高。这些指标均提示cccl对肝脏的损伤。而饲喂灵芝粉(GLP)的动物在所有先前状态生物标志物方面均表现出显著(p≤0.05)的改善,表明其对肝细胞损伤具有保护作用。在应用GLP浓度和所有测量标记物的改善水平之间记录了正剂量反应。综上所述,GLP对cccl - 4诱导的肝脏疾病具有保护作用。目前的研究建议,藻类粉的浓度可达5% (w/w),在对志愿者进行试验研究后,将其纳入日常饮食、饮料和食品补充中。
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引用次数: 3
Role of Oxidant/Antioxidant Status in the Pathogenesis of Iron-Deficiency Anemia: Case Study on Children of Qalyubiyya and Minoufiya Governorates, Egypt 氧化剂/抗氧化状态在缺铁性贫血发病机制中的作用:对埃及Qalyubiyya和Minoufiya省儿童的案例研究
Pub Date : 2020-06-01 DOI: 10.21608/BNNI.2021.164215
Eman B. Mehram, Sara A. Ahmed, Y. Elhassaneen
Iron- deficiency anemia (IDA) is anemia due to insufficient iron. It is one of the major causes of morbidity and mortality worldwide affecting people of all ages in both developed and developing countries. The present study aims to investigate the role of oxidative/antioxidant status in the pathogenesis of IDA through a case study on children of Qalyubiyya and Minoufiya Governorates, Egypt. 119 with IDA and 150 healthy control, boys and girls, infants and young children, aged zero months to 6 years, were selected for the study from Rural Health Units and Maternity and Child Care Centers, Qalyubiyya and Minoufiya Governorates, Egypt. Based on hematological and biochemical analysis, the mean hemoglobin (Hb) level, mean corpuscular volume (MCV), reticulocyte hemoglobin content, serum iron and serum ferritin were significantly lower in infants and young children with IDA than healthy control. The opposite direction was observed for the red blood cell distribution width (RDW). The antioxidant defense system parameters including [enzymes (glutathione peroxidase, GSH-Px; glutathione reductase, GSH-Rd; superoxide dismutase, SOD and catalase, CAT) activities and none-enzymatic levels (glutathione, GSH and vitamins A, C and E)] of infants and young children with IDA were significantly (P≤0.05) lower. While the oxidative stress parameters thiobarbituric acid reactive substances, TBARS and nitric oxide, NO2 were significantly higher than the control group. In conclusion, oxidant/antioxidant status may play a role in the Pathogenesis of Iron-Deficiency Anemia.
缺铁性贫血(IDA)是由于缺铁引起的贫血。它是世界范围内影响发达国家和发展中国家所有年龄人群发病和死亡的主要原因之一。本研究旨在通过对埃及Qalyubiyya省和Minoufiya省儿童的案例研究,探讨氧化/抗氧化状态在IDA发病机制中的作用。研究人员从埃及Qalyubiyya省和Minoufiya省的农村卫生单位和妇幼保健中心选择了119名IDA患者和150名健康对照,包括0个月至6岁的男孩和女孩、婴儿和幼儿。根据血液学和生化分析,IDA患儿的平均血红蛋白(Hb)水平、平均红细胞体积(MCV)、网织红细胞血红蛋白含量、血清铁和血清铁蛋白均显著低于健康对照组。红细胞分布宽度(RDW)方向相反。抗氧化防御系统参数包括[酶](谷胱甘肽过氧化物酶,GSH-Px;谷胱甘肽还原酶;IDA婴幼儿超氧化物歧化酶(SOD)、过氧化氢酶(CAT)活性及非酶(谷胱甘肽、谷胱甘肽及维生素A、C、E)水平显著(P≤0.05)降低。而氧化应激参数硫代巴比妥酸活性物质、TBARS和一氧化氮、NO2均显著高于对照组。综上所述,氧化/抗氧化状态可能在缺铁性贫血的发病机制中起作用。
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引用次数: 3
Effect of Fresh Red radish Roots Juice on some Bio-marker for hypertrophy of adipose tissue in Obese Rats 新鲜红萝卜根汁对肥胖大鼠脂肪组织增厚生物标志物的影响
Pub Date : 2020-02-01 DOI: 10.21608/bnni.2020.108366
S. Ghozy, Rehab Ibrahim Tag Al Deen
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引用次数: 0
Does Fresh Air make the Difference; a Comparative Study in Vitamin D Status among College Adolescent Females from Giza and Red Sea Governorates 新鲜空气有影响吗?吉萨省和红海省女大学生维生素D水平的比较研究
Pub Date : 2019-06-01 DOI: 10.21608/bnni.2019.55468
Dina Is, el-Sayed Mm, Salem Ah
The level of air pollution is negatively associated with the amount of solar ultra-violet ray B (UVB) that reaches earth surface. So, more pollutant areas lead to less UVB passage and consequently, 25 (OH) vitamin D cutaneous syntheses reduces. The research was carried out to study the effect of some biological, behavioral, and environmental factors on vitamin D level among college adolescent females from Red Sea and Giza governorates. A convenient sample consisted of 151 first grade university female youth was selected. Written consent was an initial basic step. Vitamin D intake was assessed and serum calcium, phosphorus, alkaline phosphatase, 25-hydroxyvitamin D [25(OH) D], and parathyroid hormone (PTH), were measured. Food intake was compared to the recommended dietary allowances. Results revealed that majority of respondents (92.0%) were veiled and exposed to sun at noon time and 61.0 % mentioned that sun- exposure took more than an hour. Waist circumference (WC) and waist to height ratio (WC to Ht) in Giza sample and increased fish consumption per week in Red Sea sample showed a positive effect on vitamin D status. Spring season had a negative influential effect on Giza participants. This study concluded that lack of sun exposure as the main cause of vitamin D deficiency in college female, there is also limited awareness of the association between sun exposure and vitamin D synthesis. Fresh air and good food practices could aid in solving health problems with such an influence as hypovitaminosis D. This study emphasized the need for further vitamin D assessment and intervention by supplementation or fortification of a staple food item. There is also an urgent need for public education to improve vitamin D- related practice and to minimize health hazards of improper exposure to UV B rays.
空气污染的程度与到达地球表面的太阳紫外线B (UVB)的数量呈负相关。因此,更多的污染区域导致较少的UVB通过,因此,25 (OH)维生素D的皮肤合成减少。本研究旨在研究一些生物、行为和环境因素对红海省和吉萨省女大学生维生素D水平的影响。选取151名大学一年级女青年作为方便样本。书面同意是最初的基本步骤。评估维生素D摄入量,测定血清钙、磷、碱性磷酸酶、25-羟基维生素D [25(OH) D]和甲状旁腺激素(PTH)。将食物摄入量与推荐的膳食允许量进行比较。调查结果显示,大部份受访者(92.0%)在中午会蒙上面纱及日晒,61.0%受访者表示日晒时间超过一小时。吉萨样本的腰围(WC)和腰高比(WC to Ht)和红海样本每周增加的鱼类食用量对维生素D水平有积极影响。春季对吉萨的参与者有负面影响。这项研究得出的结论是,缺乏阳光照射是导致大学女生维生素D缺乏的主要原因,人们对阳光照射与维生素D合成之间关系的认识也很有限。新鲜空气和良好的饮食习惯可以帮助解决诸如维生素D缺乏症等健康问题。这项研究强调需要通过补充或强化主食来进一步评估和干预维生素D。此外,迫切需要进行公众教育,以改善与维生素D有关的做法,并尽量减少不当暴露于紫外线B射线对健康的危害。
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引用次数: 0
Vitamin D Status among First Grade University Female Students 大学一年级女生维生素D状况调查
Pub Date : 2019-06-01 DOI: 10.21608/bnni.2019.55476
Dina Is, Nefisa Hb, Afaf Hs, Mohamed Ms
The present work was carried out to study the vitamin D status among first grade university female students.125First grade university apparently healthy female youth who were attending Helwan University were conveniently selected. A written consent was obtained. They were subjected to: anthropometric measurements, Dietary assessment by 24 hours dietary recall, frequency food sheet, and laboratory evaluation of vitamin D, parathyroid hormone, calcium, phosphorus and alkaline phosphatase. The energy and nutrients’ content were analyzed using the food composition table of the National Nutrition Institute.Food intake was also compared to the recommended dietary allowances by WHO/FAO.This result revealed that 53.0% of the participants were interviewed in autumn; of them 26.0% had normal serum vitamin D level, 62.0% had insufficient values and 12.0% had their results in the deficient range.40.0% of participants were interviewed in spring and their vitamin D results had nearly the same distribution. In addition to there was a significant correlation between vitamin D metabolic state and season of the year.This study concluded that there was a high prevalence of low vitamin D levels among a group of apparently healthy university undergraduate in Helwan University in Cairo, Egypt. There is an urgent need for public education about the vital role of vitamin D to minimize the complications of its deficiency.This study emphasized the need for further vitamin D assessment and interventions targeted at all people.
本研究旨在了解大学一年级女生体内维生素D的状况。125 .方便地选择了在河南大学就读的身体健康的女青年。获得了书面同意。研究对象进行了人体测量、24小时饮食回顾、频率食物表评估和维生素D、甲状旁腺激素、钙、磷和碱性磷酸酶的实验室评估。采用美国国家营养研究所食品成分表对其能量和营养素含量进行了分析。还将食物摄入量与世卫组织/粮农组织建议的膳食允许量进行了比较。结果显示,53.0%的参与者在秋季进行了访谈;其中,26.0%血清维生素D水平正常,62.0%血清维生素D水平不足,12.0%血清维生素D水平处于不足范围。此外,维生素D的代谢状态与一年中的季节有显著的相关性。这项研究得出结论,在埃及开罗赫尔万大学的一群表面上健康的大学生中,维生素D水平低的比例很高。迫切需要对公众进行有关维生素D的重要作用的教育,以尽量减少缺乏维生素D的并发症。这项研究强调了进一步对所有人进行维生素D评估和干预的必要性。
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引用次数: 1
Beneficial role of quinoa and Nigella sativa seeds as antihyperuricemia in rats 藜麦和黑籽抗大鼠高尿酸血症的有益作用
Pub Date : 2019-06-01 DOI: 10.21608/bnni.2019.55466
Elman He, Morsy Gm
Tsativa seeds (NSS) and their combination on hyperuricemia. Thirty male albino rats assigned to five groups (n=6). The first these fed on the standard diet as normal control rats. The other rats (n=24), received a basal diet including a 20g /kg diet potassium oxonate to create hyperuricemia. Then ill rats divided into four groups. The hyperuricemic control group and three groups treated with added to their diet 10% QS; 4% NSS and mix from10% QS plus 4%NSS respectively. After that, the researcher calculated the biological status and estimated biochemical analysis. The results appear that high uric acid groups, in which feeding remedy diets showed no significant variation in biological parameters compared with the normal rats. The same groups indicated a significant improvement in renal function when compared with the injury group. Likewise, rising kidney tissues antioxidant status “superoxide dismutase; catalase and glutathione transferase" and decrease "malondialdehyde and interleukin-1 (IL-6)". Also, the mixture diet increased antioxidant activity. This study concluded that QS and NSS may improve kidney function and may reduce oxidative stress. This article recommended that special meals of hyperuricemic patients supplemented by a blend of QS and NSS.
人参种子及其联合治疗高尿酸血症。雄性白化大鼠30只,随机分为5组(n=6)。第一组老鼠和正常对照组老鼠一样,吃标准的食物。其他大鼠(n=24)给予基础日粮,其中包括20g /kg氧酸钾日粮,以产生高尿酸血症。然后将患病的老鼠分成四组。高尿酸血症对照组和在日粮中添加10% QS的3组;4%NSS和10% QS加4%NSS混合。之后,研究人员计算生物状态并估计生化分析。结果表明,与正常大鼠相比,高尿酸组饲喂补救饮食的大鼠在生物学参数上没有显着变化。与损伤组相比,同一组的肾功能均有显著改善。同样,肾脏组织抗氧化状态“超氧化物歧化酶”升高;过氧化氢酶和谷胱甘肽转移酶”,降低“丙二醛和白细胞介素-1 (IL-6)”。此外,混合饲料提高了抗氧化活性。本研究表明,枸杞多糖和NSS具有改善肾功能和降低氧化应激的作用。本文建议高尿酸血症患者在特殊膳食中添加QS和NSS的混合物。
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引用次数: 2
Food safety system application during production of ice cream 冰淇淋生产过程中食品安全系统的应用
Pub Date : 2019-06-01 DOI: 10.21608/bnni.2019.55469
Mohamed Moahmmady, Asmaa Abdel Wahid, Aliaa Aliaa Mohamed Hashem
ce cream is one of the main dairy products and a nutritionally food. It is one of the favorite food items to a large segment of the population particularly by children. This study investigates to hygienic quality of ice cream through the application of Food Safety System. Ninety samples were collected during the production of ice cream. Thirty samples were collected before the application of the system; thirty samples were collected after the application of the system and thirty samples were collected from swabs. The samples were examined for the presence of, coliforms, fecal coliforms, Bacillus cereus, Staphylococcus aureus, mold, and yeast count. The obtained results indicated that the microbial count of samples before the application of the Food Safety System was higher than those after the application of the system. They ranged between 1.2 x 106 to 1.8 x 103, 8.0 x 101 to negative, 2 x 102 to negative, 7.0 x 102 to 1.9 x 102 and 2.4 x 105 to 2.3 x 103 / gm in the packaging stage at aerobic total count, coliforms, Bacillus cereus, Staphylococcus aureus, mold and yeast count respectively, while fecal coliforms were not detected in both before and after system application.
冰淇淋是主要的乳制品之一,也是一种营养丰富的食品。它是大部分人,尤其是孩子们最喜欢的食物之一。本研究应用食品安全体系对冰淇淋的卫生质量进行了考察。在冰淇淋生产过程中采集了90个样品。应用该系统前采集了30份样本;应用该系统后采集30份样本,拭子采集30份样本。对样品进行大肠菌群、粪便大肠菌群、蜡样芽孢杆菌、金黄色葡萄球菌、霉菌和酵母计数的检测。结果表明,应用食品安全系统前的样品微生物计数高于应用系统后的样品。包装阶段的好氧总计数、大肠菌群、蜡样芽孢杆菌、金黄色葡萄球菌、霉菌和酵母菌计数分别为1.2 × 106 ~ 1.8 × 103、8.0 × 101 ~阴性、2 × 102 ~阴性、7.0 × 102 ~ 1.9 × 102和2.4 × 105 ~ 2.3 × 103 / gm,而在系统应用前后均未检测到粪便大肠菌群。
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引用次数: 0
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Bulletin of the National Nutrition Institute of the Arab Republic of Egypt
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