Pub Date : 2021-12-01DOI: 10.21608/bnni.2021.233695
Mai Ghareb, O. Nassar
he main objective of conducting the current study is to investigate the dietary behavioral attitudes and common dietary pattern that occur among autistic children. Fifty-six subjects diagnosed with autism spectrum disorders (ASD) involved in the study aged from 3-20 years old. All the participants filled out a survey that included questions about lifestyle, family history with ASD, dietary patterns of a specific food, allergies, gastrointestinal (GI) symptoms and measured body mass index (BMI). The collected data showed that dietary attitudes of autistic children are almost normal as 50% of participants consume 3 meals per day, and 14.3% have 4 meals per day. In addition, 80.4% (n= 45) of children were having breakfast every day. Also, based on the collected data GI problems were been prevalence among 32% of the participants. Most of the subjects (85.7%) do not suffer from milk allergies; also, most of them (91%) are not following either casein or gluten free diets. There are no significant differences in BMI between the children with and without GI problems (p=.838, independent samples t-test). In addition, BMI is not associated with the severity level of GI problems (p=0.884, ANOVA test).
{"title":"Evaluation of the dietary behavioral attitudes and common dietary pattern among Children with autism spectrum disorders","authors":"Mai Ghareb, O. Nassar","doi":"10.21608/bnni.2021.233695","DOIUrl":"https://doi.org/10.21608/bnni.2021.233695","url":null,"abstract":"he main objective of conducting the current study is to investigate the dietary behavioral attitudes and common dietary pattern that occur among autistic children. Fifty-six subjects diagnosed with autism spectrum disorders (ASD) involved in the study aged from 3-20 years old. All the participants filled out a survey that included questions about lifestyle, family history with ASD, dietary patterns of a specific food, allergies, gastrointestinal (GI) symptoms and measured body mass index (BMI). The collected data showed that dietary attitudes of autistic children are almost normal as 50% of participants consume 3 meals per day, and 14.3% have 4 meals per day. In addition, 80.4% (n= 45) of children were having breakfast every day. Also, based on the collected data GI problems were been prevalence among 32% of the participants. Most of the subjects (85.7%) do not suffer from milk allergies; also, most of them (91%) are not following either casein or gluten free diets. There are no significant differences in BMI between the children with and without GI problems (p=.838, independent samples t-test). In addition, BMI is not associated with the severity level of GI problems (p=0.884, ANOVA test).","PeriodicalId":9493,"journal":{"name":"Bulletin of the National Nutrition Institute of the Arab Republic of Egypt","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77744019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-01DOI: 10.21608/bnni.2021.231583
Hoda El Gezery, H. Sheha
uercetin is a flavonoid that is present in many different foods. Quercetin has several health advantages, including improved non-communicable diseases. Acrylamide can be produced by the Maillard reaction of amino acid and reducing sugars. As a result, the effects of varying amounts of quercetin on the harmful effect of toxic dietary acrylamide were studied. Forty male albino rats (Sprague Dawley) have been split into five groups (eight rats each), and every group was fed an experimental diet for 28 days. The negative control group was given only a baseline diet, whereas the positive control group was intake both a baseline diet and 4 μg/kg body weight (BW) of acrylamide each day. Groups 2, 3, and 4 were fed a basal diet comprising of 4 μg kg/BW each day of acrylamide with 50, 100, and 200 mg of quercetin powder/kg BW/day. The results showed that treatment with acrylamide alone significantly, (p≤ 0.05) decreased the relative body weight; feed efficiency ratio (FER), feed intake and increased tested relative organs weight. In addition, the results revealed that the positive control group had an inhibitory impact on butyrylcholinesterase, lactate dehydrogenase activity, the immunity index, an increase in malondialdehyde activities, and the harmful effect on the histological structure of the rats' liver and brain. Whereas treatment with different levels of quercetin significantly improved all tested parameters especially, at a high dose of quercetin (200 mg). For that, adding quercetin or their dietary sources in fried meals may be significant to reduce hazardous acrylamide.
{"title":"Biological and biochemical studies on the effect of different quercetin levels of toxic dietary acrylamide on rats","authors":"Hoda El Gezery, H. Sheha","doi":"10.21608/bnni.2021.231583","DOIUrl":"https://doi.org/10.21608/bnni.2021.231583","url":null,"abstract":"uercetin is a flavonoid that is present in many different foods. Quercetin has several health advantages, including improved non-communicable diseases. Acrylamide can be produced by the Maillard reaction of amino acid and reducing sugars. As a result, the effects of varying amounts of quercetin on the harmful effect of toxic dietary acrylamide were studied. Forty male albino rats (Sprague Dawley) have been split into five groups (eight rats each), and every group was fed an experimental diet for 28 days. The negative control group was given only a baseline diet, whereas the positive control group was intake both a baseline diet and 4 μg/kg body weight (BW) of acrylamide each day. Groups 2, 3, and 4 were fed a basal diet comprising of 4 μg kg/BW each day of acrylamide with 50, 100, and 200 mg of quercetin powder/kg BW/day. The results showed that treatment with acrylamide alone significantly, (p≤ 0.05) decreased the relative body weight; feed efficiency ratio (FER), feed intake and increased tested relative organs weight. In addition, the results revealed that the positive control group had an inhibitory impact on butyrylcholinesterase, lactate dehydrogenase activity, the immunity index, an increase in malondialdehyde activities, and the harmful effect on the histological structure of the rats' liver and brain. Whereas treatment with different levels of quercetin significantly improved all tested parameters especially, at a high dose of quercetin (200 mg). For that, adding quercetin or their dietary sources in fried meals may be significant to reduce hazardous acrylamide.","PeriodicalId":9493,"journal":{"name":"Bulletin of the National Nutrition Institute of the Arab Republic of Egypt","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89669461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-01DOI: 10.21608/bnni.2021.233310
Seham Orabi, Taha A Abd-ElRazic, Hanaa H. Elsayed
lasticizers (diethyl phthalate (DEP), di-butyl phthalate (DBP), benzyl butyl phthalate (BBP), and diethyl hexyl phthalate (DEHP) are widely used in the manufacture of plastics. Phthalates are not covalently bound to the plastic matrix and can leach into food during packaging. This study investigated the migration of phthalate derivatives from Polyethylene terephthalate (PET) bottles into their water and vinegar under different storage conditions. Gas chromatography (GC) with a mass spectrometry (MS) system is used. The results showed that the highest migration level was DEHP levels after 4 months at 40ºC reached 62.5 and 51.9 µg/L in bottled water and vinegar these values were 10.4 and 8.65 times higher than the upper limit for maximum contamination level (MCL) in drinking water as regulated by U.S.EPA, which equal 6.0 µg/L for DEHP.
{"title":"Migration of Plasticizers from Polyethylene Terephthalate Bottles to Vinegar and Water via different Temperature and Storage Periods","authors":"Seham Orabi, Taha A Abd-ElRazic, Hanaa H. Elsayed","doi":"10.21608/bnni.2021.233310","DOIUrl":"https://doi.org/10.21608/bnni.2021.233310","url":null,"abstract":"lasticizers (diethyl phthalate (DEP), di-butyl phthalate (DBP), benzyl butyl phthalate (BBP), and diethyl hexyl phthalate (DEHP) are widely used in the manufacture of plastics. Phthalates are not covalently bound to the plastic matrix and can leach into food during packaging. This study investigated the migration of phthalate derivatives from Polyethylene terephthalate (PET) bottles into their water and vinegar under different storage conditions. Gas chromatography (GC) with a mass spectrometry (MS) system is used. The results showed that the highest migration level was DEHP levels after 4 months at 40ºC reached 62.5 and 51.9 µg/L in bottled water and vinegar these values were 10.4 and 8.65 times higher than the upper limit for maximum contamination level (MCL) in drinking water as regulated by U.S.EPA, which equal 6.0 µg/L for DEHP.","PeriodicalId":9493,"journal":{"name":"Bulletin of the National Nutrition Institute of the Arab Republic of Egypt","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86169780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-01DOI: 10.21608/bnni.2021.229715
F. Ashkanani, Maryam A Al Dwairji, W. Husain, Nawal M. Al Qaoud
dolescents (aged 10 to 19 years) represent the largest generation in Kuwait. The vulnerability of this age group to malnutrition is well documented due to increase nutritional requirements, an unhealthy food environment, and to inadequate attention in most health and nutrition awareness programs. Objective to assess the nutritional status, including dietary and anthropometric parameters, among school children in Kuwait. Three days of face-to-face multiple-pass 24-hour recalls were collected from 479 children in a cross-sectional design study. Weight, height, and blood hemoglobin were measured. Girls were more likely to be overweight (27.1%), whereas boys were more likely to be obese (25.5%), P = 0.028. Results show that most Kuwaiti adolescents exceed the recommendations for energy and most nutrients, except vitamin E, vitamin D, and calcium. Within middle school, the average energy intake was 2591.2 and 2201.4 kcal/day; while in the high school group was 2570.1 and 2056.0 kcal/day for boys and girls, respectively. Breakfast consumers have a higher intake of all nutrients than breakfast-skippers do. Adolescents, who are physically active, have a significantly higher intake of energy, carbohydrate, protein, fat, and fiber than inactive adolescents do. Physically active adolescents have a significantly higher intake of folate, iron, calcium, and zinc than inactive adolescents do. Conclusion: Monitoring adolescent dietary intake and nutrition status is key to preventing adolescent malnutrition in the short term and diet-related disease in the long term. Targeted nutrition intervention program and reevaluation of school feeding program and canteens are needed.
{"title":"Dietary Intakes among Kuwait Adolescents: Identifying Dietary and Non-dietary Determinants","authors":"F. Ashkanani, Maryam A Al Dwairji, W. Husain, Nawal M. Al Qaoud","doi":"10.21608/bnni.2021.229715","DOIUrl":"https://doi.org/10.21608/bnni.2021.229715","url":null,"abstract":"dolescents (aged 10 to 19 years) represent the largest generation in Kuwait. The vulnerability of this age group to malnutrition is well documented due to increase nutritional requirements, an unhealthy food environment, and to inadequate attention in most health and nutrition awareness programs. Objective to assess the nutritional status, including dietary and anthropometric parameters, among school children in Kuwait. Three days of face-to-face multiple-pass 24-hour recalls were collected from 479 children in a cross-sectional design study. Weight, height, and blood hemoglobin were measured. Girls were more likely to be overweight (27.1%), whereas boys were more likely to be obese (25.5%), P = 0.028. Results show that most Kuwaiti adolescents exceed the recommendations for energy and most nutrients, except vitamin E, vitamin D, and calcium. Within middle school, the average energy intake was 2591.2 and 2201.4 kcal/day; while in the high school group was 2570.1 and 2056.0 kcal/day for boys and girls, respectively. Breakfast consumers have a higher intake of all nutrients than breakfast-skippers do. Adolescents, who are physically active, have a significantly higher intake of energy, carbohydrate, protein, fat, and fiber than inactive adolescents do. Physically active adolescents have a significantly higher intake of folate, iron, calcium, and zinc than inactive adolescents do. Conclusion: Monitoring adolescent dietary intake and nutrition status is key to preventing adolescent malnutrition in the short term and diet-related disease in the long term. Targeted nutrition intervention program and reevaluation of school feeding program and canteens are needed.","PeriodicalId":9493,"journal":{"name":"Bulletin of the National Nutrition Institute of the Arab Republic of Egypt","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84329252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.21608/bnni.2021.221965
Fardous S H Soliman, Hanaa H. Elsayed, Athar Elkafas, Mona M. Elghareeb, Rasha El kolally, Suzan El bakry
anotechnology nearly covered every single aspect of the food industry including packing and processing of food, it affects contribution, development, and sustainability in the food sector by advanced technology. Nanotechnology uses materials and structures at the nanometer scale. The application of nanotechnology enables food preservation, increases the expiration date, and facilitates nutrition enrichment. Despite the benefits of nanotechnology, there are vital concerns regarding its usage, since the buildup of nanoparticles (NPs) in humans and the environment may result in various safety and health hazards. The toxicological basics and risk evaluation of nanomaterials should be thoroughly investigated in novel foods. A lot of work is needed to raise community awareness about the usage of nanoparticles in food and their impact on health.
{"title":"Review: Nanotechnology in Food Industry","authors":"Fardous S H Soliman, Hanaa H. Elsayed, Athar Elkafas, Mona M. Elghareeb, Rasha El kolally, Suzan El bakry","doi":"10.21608/bnni.2021.221965","DOIUrl":"https://doi.org/10.21608/bnni.2021.221965","url":null,"abstract":"anotechnology nearly covered every single aspect of the food industry including packing and processing of food, it affects contribution, development, and sustainability in the food sector by advanced technology. Nanotechnology uses materials and structures at the nanometer scale. The application of nanotechnology enables food preservation, increases the expiration date, and facilitates nutrition enrichment. Despite the benefits of nanotechnology, there are vital concerns regarding its usage, since the buildup of nanoparticles (NPs) in humans and the environment may result in various safety and health hazards. The toxicological basics and risk evaluation of nanomaterials should be thoroughly investigated in novel foods. A lot of work is needed to raise community awareness about the usage of nanoparticles in food and their impact on health.","PeriodicalId":9493,"journal":{"name":"Bulletin of the National Nutrition Institute of the Arab Republic of Egypt","volume":"98 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75024950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.21608/bnni.2021.216441
Gihan Ahmad, Naglaa M. Mostafa, T. Elzayat, G. Soliman, Eman Al Morsi, Eman Elhabashi
orld Health Organization recommends exclusive breastfeeding, for the first six months of the infant’s life, due to the unique composition of breast milk (BM). For working nursing mothers, practicing exclusive breastfeeding can be a challenge. Objectives: To assess the effect of storing BM at different temperatures and durations on selected macronutrients and micronutrients content. Methods: Sixty BM samples were collected in sterile polypropylene containers from twenty mothers at the National Nutrition Institute. Samples from each mother were divided into 3 sets: the first was analyzed immediately, the second were analyzed after storage in refrigerator first shelf (4:6C) for 24 hours, the third were analyzed after storage in the freezer (-4:-8C) for one week. Results: Refrigeration resulted in a statistically significant decrease in the Vitamin A and C content of BM while freezing resulted in a statistically significant decrease in Lactose, Vitamin A, C, and E content of BM. Despite all declines in the studied macronutrients and micronutrients, their concentrations remained within the acceptable international reference ranges. Conclusion: Breastfeeding practice should not be stopped or replaced. Changes found in stored BM were found to be of little significance from the nutrition point of view.
{"title":"Impact of storage temperature and duration on the nutritive content quality of Human Breastmilk","authors":"Gihan Ahmad, Naglaa M. Mostafa, T. Elzayat, G. Soliman, Eman Al Morsi, Eman Elhabashi","doi":"10.21608/bnni.2021.216441","DOIUrl":"https://doi.org/10.21608/bnni.2021.216441","url":null,"abstract":"orld Health Organization recommends exclusive breastfeeding, for the first six months of the infant’s life, due to the unique composition of breast milk (BM). For working nursing mothers, practicing exclusive breastfeeding can be a challenge. Objectives: To assess the effect of storing BM at different temperatures and durations on selected macronutrients and micronutrients content. Methods: Sixty BM samples were collected in sterile polypropylene containers from twenty mothers at the National Nutrition Institute. Samples from each mother were divided into 3 sets: the first was analyzed immediately, the second were analyzed after storage in refrigerator first shelf (4:6C) for 24 hours, the third were analyzed after storage in the freezer (-4:-8C) for one week. Results: Refrigeration resulted in a statistically significant decrease in the Vitamin A and C content of BM while freezing resulted in a statistically significant decrease in Lactose, Vitamin A, C, and E content of BM. Despite all declines in the studied macronutrients and micronutrients, their concentrations remained within the acceptable international reference ranges. Conclusion: Breastfeeding practice should not be stopped or replaced. Changes found in stored BM were found to be of little significance from the nutrition point of view.","PeriodicalId":9493,"journal":{"name":"Bulletin of the National Nutrition Institute of the Arab Republic of Egypt","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84906856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.21608/bnni.2021.228688
Gihan Ahmad, Mona Abd-Elmotaleb, Hanaa Ahmed, E. Hammad
ron Deficiency Anemia is the most common type of anemia related to malnutrition worldwide. It represents a major problem in developing countries. Purpose: To determine the effect of dietary intervention only on the occurrence of IDA. Methods: In 6 articles with 8 eligible outcomes, a total of 676 individuals were included within the present systematic review with no of cases 339 and 337 control. Dietary intervention is mainly to eat about 3040 g of liver, sheep liver, chicken liver, or 12 eggs, or 30 red dates, etc. before or after the meal once a day. Result: clinical recovery—clinical symptoms disappeared completely, and hemoglobin returned to normal. Clinically effective—clinical symptoms relieved, and the rise of HB >15 g/dl. Invalid— clinical symptoms did not improve or obviously improve, and the rise of HB to 15 g/dl. Dietary intervention was associated with an average change in clinical effectiveness from 94.0% to 100.0%. The clinical effect was increased in dietary intervention in all six trials, among which three trials had a statistical increase of clinical effect. Tests for heterogeneity showed no significant differences across studies, thus the fixed effect model was employed. The overall pooled estimate of or in the dietary intervention on children with IDA was 5.03 (95%) CI: 3.098.18, Z = 6.50, P<0.001. Conclusion: Dietary intervention on children with IDA was established that had a beneficial effect.
缺铁性贫血是世界范围内与营养不良有关的最常见的贫血类型。这是发展中国家的一个主要问题。目的:确定饮食干预对IDA发生的影响。方法:本系统评价纳入6篇纳入8个合格结局的文献，共纳入676例，无病例339例，对照组337例。饮食干预主要是每天餐前或餐后食用3040g左右的肝脏、羊肝、鸡肝，或12个鸡蛋、或30个红枣等。结果:临床痊愈-临床症状完全消失，血红蛋白恢复正常。临床有效-临床症状缓解，HB升高>15 g/dl。无效-临床症状无改善或明显改善，且HB升高至15 g/dl。饮食干预与临床疗效的平均变化相关，从94.0%到100.0%。6项试验均提高了饮食干预的临床效果，其中3项试验的临床效果有统计学上的提高。异质性检验显示各研究间无显著差异，故采用固定效应模型。饮食干预对IDA患儿的总体汇总估计为5.03 (95%)CI: 3.098.18, Z = 6.50, P<0.001。结论:饮食干预对IDA患儿具有良好的效果。
{"title":"Systematic Review: Dietary Intervention only Decreases the Risk of Iron Deficiency Anemia among Children","authors":"Gihan Ahmad, Mona Abd-Elmotaleb, Hanaa Ahmed, E. Hammad","doi":"10.21608/bnni.2021.228688","DOIUrl":"https://doi.org/10.21608/bnni.2021.228688","url":null,"abstract":"ron Deficiency Anemia is the most common type of anemia related to malnutrition worldwide. It represents a major problem in developing countries. Purpose: To determine the effect of dietary intervention only on the occurrence of IDA. Methods: In 6 articles with 8 eligible outcomes, a total of 676 individuals were included within the present systematic review with no of cases 339 and 337 control. Dietary intervention is mainly to eat about 3040 g of liver, sheep liver, chicken liver, or 12 eggs, or 30 red dates, etc. before or after the meal once a day. Result: clinical recovery—clinical symptoms disappeared completely, and hemoglobin returned to normal. Clinically effective—clinical symptoms relieved, and the rise of HB >15 g/dl. Invalid— clinical symptoms did not improve or obviously improve, and the rise of HB to 15 g/dl. Dietary intervention was associated with an average change in clinical effectiveness from 94.0% to 100.0%. The clinical effect was increased in dietary intervention in all six trials, among which three trials had a statistical increase of clinical effect. Tests for heterogeneity showed no significant differences across studies, thus the fixed effect model was employed. The overall pooled estimate of or in the dietary intervention on children with IDA was 5.03 (95%) CI: 3.098.18, Z = 6.50, P<0.001. Conclusion: Dietary intervention on children with IDA was established that had a beneficial effect.","PeriodicalId":9493,"journal":{"name":"Bulletin of the National Nutrition Institute of the Arab Republic of Egypt","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83669212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.21608/bnni.2021.221596
Samah A. Elsemelawy, M. Gharib, Y. Elhassaneen
iabetes is a metabolic condition characterized by hyperglycemia and insufficient insulin production or activity. Since ancient times, the reishi mushroom (Ganoderma lucidum) has been utilized as a traditional herbal treatment. Aim of the study: investigate the effectiveness of Ganoderma lucidum extract (GLE) to ameliorate hyperglycemia and liver/kidney functions in streptozotocin-induced type 2 diabetic rats. Six groups of adult male Sprague– Dawley rats were formed at random. Group 1: Normal rats with a normal diet. Group 2: Diabetic rats by injection Streptozotocin (STZ) and fed without intervention as a model control group, Groups 3-6: GLE, diabetic rats with intervention groups receiving GLE at doses of 200, 400, 600, and 800 mg/kg BW via oral gavage for 28 days. After GLE intervention, blood samples were tested for changes in hyperglycemia, glycosylated hemoglobin, insulin, liver, and kidney functioning. Results: Within the first two weeks of GLE intervention, blood glucose levels were reduced, and insulin levels in diabetic rats in the GLE group were considerably higher at four weeks than in the positive control group. Furthermore, it was discovered that GLE intervention significantly improved the liver and kidney functioning of diabetic rats. Conclusion: This research suggests that GLE consumption may help reduce blood glucose levels by boosting insulin production. Meanwhile, GLE therapy was linked to a reduction in diabetes problems in type 2 diabetic rats by improving their liver and renal functioning.
{"title":"Reishi Mushroom (Ganoderma lucidum) Extract Ameliorate Hyperglycemia and Liver/Kidney Functions in Streptozotocin-induced Type 2 Diabetic Rats","authors":"Samah A. Elsemelawy, M. Gharib, Y. Elhassaneen","doi":"10.21608/bnni.2021.221596","DOIUrl":"https://doi.org/10.21608/bnni.2021.221596","url":null,"abstract":"iabetes is a metabolic condition characterized by hyperglycemia and insufficient insulin production or activity. Since ancient times, the reishi mushroom (Ganoderma lucidum) has been utilized as a traditional herbal treatment. Aim of the study: investigate the effectiveness of Ganoderma lucidum extract (GLE) to ameliorate hyperglycemia and liver/kidney functions in streptozotocin-induced type 2 diabetic rats. Six groups of adult male Sprague– Dawley rats were formed at random. Group 1: Normal rats with a normal diet. Group 2: Diabetic rats by injection Streptozotocin (STZ) and fed without intervention as a model control group, Groups 3-6: GLE, diabetic rats with intervention groups receiving GLE at doses of 200, 400, 600, and 800 mg/kg BW via oral gavage for 28 days. After GLE intervention, blood samples were tested for changes in hyperglycemia, glycosylated hemoglobin, insulin, liver, and kidney functioning. Results: Within the first two weeks of GLE intervention, blood glucose levels were reduced, and insulin levels in diabetic rats in the GLE group were considerably higher at four weeks than in the positive control group. Furthermore, it was discovered that GLE intervention significantly improved the liver and kidney functioning of diabetic rats. Conclusion: This research suggests that GLE consumption may help reduce blood glucose levels by boosting insulin production. Meanwhile, GLE therapy was linked to a reduction in diabetes problems in type 2 diabetic rats by improving their liver and renal functioning.","PeriodicalId":9493,"journal":{"name":"Bulletin of the National Nutrition Institute of the Arab Republic of Egypt","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90626088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.21608/bnni.2021.215748
A. Emara, M. Kassem, Areej Yassin, Asmaa Abd-elwahed, H. Sobhy, Hanaa H. Elsayed
1) Chemistry of Nutrition and metabolism department, National Nutrition Institute (NNI) –Cairo, Egypt 2) Food science department, National Nutrition Institute (NNI) –Cairo, Egypt 3) Nutrition departmentHepatology and Tropical Medicine National Institute–Cairo, Egypt 4) Field Studies and Survey department, National Nutrition Institute (NNI) –Cairo, Egypt 5) Natural resources departmentFaculty of African Post Graduated Studies–Cairo, Egypt
{"title":"Dietary Intervention of Coconut Liquid to Mitigate the Hyperlipidemia in Rats","authors":"A. Emara, M. Kassem, Areej Yassin, Asmaa Abd-elwahed, H. Sobhy, Hanaa H. Elsayed","doi":"10.21608/bnni.2021.215748","DOIUrl":"https://doi.org/10.21608/bnni.2021.215748","url":null,"abstract":"1) Chemistry of Nutrition and metabolism department, National Nutrition Institute (NNI) –Cairo, Egypt 2) Food science department, National Nutrition Institute (NNI) –Cairo, Egypt 3) Nutrition departmentHepatology and Tropical Medicine National Institute–Cairo, Egypt 4) Field Studies and Survey department, National Nutrition Institute (NNI) –Cairo, Egypt 5) Natural resources departmentFaculty of African Post Graduated Studies–Cairo, Egypt","PeriodicalId":9493,"journal":{"name":"Bulletin of the National Nutrition Institute of the Arab Republic of Egypt","volume":"110 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76737977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.21608/bnni.2021.216733
Gihan Ahmad, H. Abdel-Salam, Naglaa Mohammed Abd Alfattah, Magda Kostandy
he respiratory allergic ailment is an inflammatory condition joined by oxidative stress. Extra elements of anti-inflammatory factors such as antioxidants may have a curative effect. This study planned the status of vitamins (A, E &C) in food and sera of young some Egyptian children with allergic asthma coming to the National Nutrition Institute (NNI). The study inclsive104 children who attended the pediatric outpatient clinic of NNI during August and September 2014. The subjects in the study, both boys and girls, were randomly selected within the age range from 7-10 years. Asthma signs were assessed by a Chinese version of the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire. Data on nutritional status had been collected using specially designed questionnaires to cover required information on food intake (24-hour recall) and dietary pattern (food frequency) for chosen items. Body mass index was calculated based on the bodyweight within kilograms divided by the square of the body height in meters. After an overnight fast of 12 hours, blood samples of 5ml were collected from the children to determine serum levels of vitamin A, E, and C. The outcome revealed decreased daily intake and serum content from vitamin A, E, and C within asthmatic children parallel to normal children. Conclusion Despite the low level of intake antioxidants or there in serum within asthmatic children with no significant differences, they had signs of asthma, which confirms that the decrease in these vitamins, even a small amount, leads to asthma sensitivity.
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