Pub Date : 2023-01-01DOI: 10.21608/bnni.2023.310139
A. El-Gawish
: iabetes mellitus (DM) is a serious health issue for the general public. In this work, male diabetic rats were used to determine the impact of Citrullus colocynthis and Phyllanthus Emblica fruits ethanolic extract (EECC and EEPE). Six groups of thirty mature rats (male Sprague Dawley) were examined. In the first group, normal rats have been fed a balanced diet served as the negative control group (C); in the second group, diabetic rats served as the control positive (C+). Diabetic rats in groups 3, 4, 5, and 6 received daily treatments of (200 and 400 mg kg -1 body weight (BW) EECC and EEPE, respectively. After four weeks of treatment, Biochemical indicators were examined in all blood samples. Streptozotocin was injected and resulted in a significant reduction in feed intake (FI), feed efficiency (FER) body weight gain (BWG), serum insulin, high-density lipoprotein (HDL-c), globulin, albumin, and total protein, as well as antioxidant enzymes, glutathione (GSH) and superoxide dismutase (SOD) in pancreatic tissue, whereas a significant increment was noted in serum glucose, triglyceride (TG), total cholesterol (TC), low & very low-density lipoprotein cholesterol (LDL-c and VLDL-c), atherogenic index (AI), Alkaline phosphatase (ALP), Aspartate aminotransferase (AST), alanine aminotransferase (ALT), urea, uric acid, creatinine, tumor necrosis factor-α, creatine phosphate kinase (CPK) and lactate dehydrogenase (LDH) and lipid peroxidation (MDA) in pancreatic tissue. The treatment of diabetic animals with different ethanolic extracts caused improvements in all previously measured parameters, with EEPE (400 mg kg -1 BW) showing the greatest improvement.
糖尿病(DM)是一个严重的公众健康问题。本实验以雄性糖尿病大鼠为实验对象，研究了甜瓜和余甘子乙醇提取物(EECC和EEPE)对糖尿病大鼠的影响。研究了6组30只成年雄性大鼠(Sprague Dawley)。第一组正常大鼠均衡饮食作为阴性对照组(C);第二组以糖尿病大鼠为对照阳性(C+)。3、4、5、6组糖尿病大鼠每日分别给予200、400 mg kg -1体重(BW) EECC和EEPE治疗。治疗4周后，检测各组血液生化指标。注射链脲佐菌素后，采食量(FI)、饲料效率(FER)、体增重(BWG)、血清胰岛素、高密度脂蛋白(HDL-c)、球蛋白、白蛋白、总蛋白以及胰腺组织中抗氧化酶、谷胱甘肽(GSH)和超氧化物歧化酶(SOD)显著降低，血清葡萄糖、甘油三酯(TG)、总胆固醇(TC)、低密度和极低密度脂蛋白胆固醇(LDL-c和VLDL-c)显著升高。胰腺组织的动脉粥样硬化指数(AI)、碱性磷酸酶(ALP)、天冬氨酸转氨酶(AST)、丙氨酸转氨酶(ALT)、尿素、尿酸、肌酐、肿瘤坏死因子-α、肌酸磷酸激酶(CPK)、乳酸脱氢酶(LDH)和脂质过氧化(MDA)。用不同乙醇提取物治疗糖尿病动物可改善所有先前测量的参数，其中EEPE (400 mg kg -1 BW)的改善最大。
{"title":"Evaluation The Ameliorative Effect of Alcoholic Extracts of Citrullus colocynthis and Phyllanthus Emblica Fruits on Streptozotocin-Induced Diabetes in Male Rats","authors":"A. El-Gawish","doi":"10.21608/bnni.2023.310139","DOIUrl":"https://doi.org/10.21608/bnni.2023.310139","url":null,"abstract":": iabetes mellitus (DM) is a serious health issue for the general public. In this work, male diabetic rats were used to determine the impact of Citrullus colocynthis and Phyllanthus Emblica fruits ethanolic extract (EECC and EEPE). Six groups of thirty mature rats (male Sprague Dawley) were examined. In the first group, normal rats have been fed a balanced diet served as the negative control group (C); in the second group, diabetic rats served as the control positive (C+). Diabetic rats in groups 3, 4, 5, and 6 received daily treatments of (200 and 400 mg kg -1 body weight (BW) EECC and EEPE, respectively. After four weeks of treatment, Biochemical indicators were examined in all blood samples. Streptozotocin was injected and resulted in a significant reduction in feed intake (FI), feed efficiency (FER) body weight gain (BWG), serum insulin, high-density lipoprotein (HDL-c), globulin, albumin, and total protein, as well as antioxidant enzymes, glutathione (GSH) and superoxide dismutase (SOD) in pancreatic tissue, whereas a significant increment was noted in serum glucose, triglyceride (TG), total cholesterol (TC), low & very low-density lipoprotein cholesterol (LDL-c and VLDL-c), atherogenic index (AI), Alkaline phosphatase (ALP), Aspartate aminotransferase (AST), alanine aminotransferase (ALT), urea, uric acid, creatinine, tumor necrosis factor-α, creatine phosphate kinase (CPK) and lactate dehydrogenase (LDH) and lipid peroxidation (MDA) in pancreatic tissue. The treatment of diabetic animals with different ethanolic extracts caused improvements in all previously measured parameters, with EEPE (400 mg kg -1 BW) showing the greatest improvement.","PeriodicalId":9493,"journal":{"name":"Bulletin of the National Nutrition Institute of the Arab Republic of Egypt","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78669021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.21608/bnni.2023.310137
Sara M. Heikal, Mona Hussein, Safaa Tawfik, S. Hussein
ypertension is one of the avoidable diseases, prevention can be done by adopting healthy eating habits. There is growing interest in using alternative plants and herbal as medicines to treat and prevent hypertension. The study aims to explore the knowledge of Egyptian adults about hypertension and their perspectives to control it by consumption of capsicum, garlic, and turmeric. Methods: a cross-sectional study. The 1008 participants need to fill anonymous questionnaire (Google form). They answer questions related to sociodemographic characteristics, history of hypertension, dietary habits, and use of turmeric, capsicum, and garlic to control hypertension. The study revealed (76.1 %) had a positive family history of hypertension. The prevalence of hypertension was (18.9%) in the studied group as perceived. Their knowledge about hypertension was from reading (39.3%) and social media (30.4%). (31 %) reported a reduction of salt intake to control hypertension. (30.9%) of the studied group trusted natural remedies to control BP. Participants who consume chili, garlic, and turmeric regularly noticed changes in their blood pressure (25 %, 35 %, 37.5 %) respectively. There was a significant association between the frequency of garlic, chili, and turmeric consumed and a change in blood pressure P ≤ 0.05. Conclusion: knowledge about hypertension was from reading and social media, changing dietary habits such as decreasing salt intake, and trust in herbs such as chili, garlic, and turmeric to control hypertension. Regular consumption of herbs may have a potential effect in lowering blood pressure, further studies are recommended.
{"title":"Assessment of Egyptian Adult’s Knowledge and Perspectives on Hypertension and the Role of Capsicum, Turmeric & Garlic to Control It: A Cross-Sectional Study","authors":"Sara M. Heikal, Mona Hussein, Safaa Tawfik, S. Hussein","doi":"10.21608/bnni.2023.310137","DOIUrl":"https://doi.org/10.21608/bnni.2023.310137","url":null,"abstract":"ypertension is one of the avoidable diseases, prevention can be done by adopting healthy eating habits. There is growing interest in using alternative plants and herbal as medicines to treat and prevent hypertension. The study aims to explore the knowledge of Egyptian adults about hypertension and their perspectives to control it by consumption of capsicum, garlic, and turmeric. Methods: a cross-sectional study. The 1008 participants need to fill anonymous questionnaire (Google form). They answer questions related to sociodemographic characteristics, history of hypertension, dietary habits, and use of turmeric, capsicum, and garlic to control hypertension. The study revealed (76.1 %) had a positive family history of hypertension. The prevalence of hypertension was (18.9%) in the studied group as perceived. Their knowledge about hypertension was from reading (39.3%) and social media (30.4%). (31 %) reported a reduction of salt intake to control hypertension. (30.9%) of the studied group trusted natural remedies to control BP. Participants who consume chili, garlic, and turmeric regularly noticed changes in their blood pressure (25 %, 35 %, 37.5 %) respectively. There was a significant association between the frequency of garlic, chili, and turmeric consumed and a change in blood pressure P ≤ 0.05. Conclusion: knowledge about hypertension was from reading and social media, changing dietary habits such as decreasing salt intake, and trust in herbs such as chili, garlic, and turmeric to control hypertension. Regular consumption of herbs may have a potential effect in lowering blood pressure, further studies are recommended.","PeriodicalId":9493,"journal":{"name":"Bulletin of the National Nutrition Institute of the Arab Republic of Egypt","volume":"83 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91385543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.21608/bnni.2023.310135
Naglaa Abd Al-Fattah, Areej Yassin, A. Soliman
his research sought to determine whether interactions between rat diet and the biological and metabolic responses could mitigate the side effects of the antibiotic Flummox. The addition of tomato powder that had been cooked, dried, and ground, along with 10% of lyophilized bovine liver. Out of 44 mature male rats, four main categories were developed. As a negative control, the first set only received regular meals. The third group received lyophilized bovine liver, the fourth group received tomato powder, and the second group received a fundamental diet together with Flumox as a positive control. In comparison to the Flumox group, the liver and tomato-treated groups displayed significantly lower levels of liver enzymes (ALT, AST, and ALP), kidney functions, lymphocytes, leukocytes, and oxidative stress, as well as significantly higher levels of red blood cells hemoglobin and glutathione (GSH) in the hepatic and renal tissues. One can conclude that combining some nutrients (liver, tomato) can reduce the amount of excess weight in rats and treat the many physiological and hematological aberrations caused by oxidative stress diseases connected with antibiotics.
{"title":"Protective Role of Bovine Liver and Tomato Powder Against Negative Effects of Flummox Antibiotic in Rats","authors":"Naglaa Abd Al-Fattah, Areej Yassin, A. Soliman","doi":"10.21608/bnni.2023.310135","DOIUrl":"https://doi.org/10.21608/bnni.2023.310135","url":null,"abstract":"his research sought to determine whether interactions between rat diet and the biological and metabolic responses could mitigate the side effects of the antibiotic Flummox. The addition of tomato powder that had been cooked, dried, and ground, along with 10% of lyophilized bovine liver. Out of 44 mature male rats, four main categories were developed. As a negative control, the first set only received regular meals. The third group received lyophilized bovine liver, the fourth group received tomato powder, and the second group received a fundamental diet together with Flumox as a positive control. In comparison to the Flumox group, the liver and tomato-treated groups displayed significantly lower levels of liver enzymes (ALT, AST, and ALP), kidney functions, lymphocytes, leukocytes, and oxidative stress, as well as significantly higher levels of red blood cells hemoglobin and glutathione (GSH) in the hepatic and renal tissues. One can conclude that combining some nutrients (liver, tomato) can reduce the amount of excess weight in rats and treat the many physiological and hematological aberrations caused by oxidative stress diseases connected with antibiotics.","PeriodicalId":9493,"journal":{"name":"Bulletin of the National Nutrition Institute of the Arab Republic of Egypt","volume":"89 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80269973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-01DOI: 10.21608/bnni.2022.271353
Dalia Hassan
: he fruit tree Eriobotrya japonica (EJL) performs a variety of essential functions. The current article's target was to establish the hepatoprotective effects of the phenolic and flavonoid constituents in loquat leaves (E. japonica); versus CCl4 in rats. In this study, thirty male albino rats averaging 190± 10 g were separated into two main sets: first G (-ve) was fed on a basal diet for 4 weeks and the remainder were injected by CCL 4 for induction liver injury twice weekly for 4 weeks, there are all treatment rats divided into 4 sub-groups. Second G was fed a basal diet with CCL 4 injection (2 mg /kg) (+ve) control and sets (3,4,5) fed different dried Eriobotrya japonica levels at (50,100 and 150 g/kg diet). The findings revealed that all indicators have highly significantly increased (malondialdehyde MDA, liver enzymes, lipid parameter) after CCL 4 injection, but when added EJL at different levels, all parameters were highly significantly decreased when compared with positive G, and the decreasing level was accompanied with increasing the EJL levels, this due to the phenolic and flavonoids compounds of EJL. The same effects were noticed in histological results. Bread sensory evaluation revealed the good palatability of these leaves, which could be used as ameliorating products for liver injury.
果树Eriobotrya japonica (EJL)具有多种基本功能。本文的目的是建立枇杷叶中酚类和黄酮类成分对肝脏的保护作用;与CCl4相比本研究选取平均体重190±10 g的雄性白化大鼠30只，分为两组，第一组g (-ve)饲喂基础日粮4周，其余各组注射ccl4诱导肝损伤，每周2次，连续4周，所有治疗大鼠均分为4个亚组。第二组G饲喂基础饲粮，以ccl4注射液(2 mg /kg) (+ve)为对照，第3、4、5组饲喂不同水平(50、100和150 G /kg饲粮)的干枯粳稻。结果表明:注射ccl4后，各指标(丙二醛MDA、肝酶、脂质参数)均极显著升高，而添加不同水平的EJL后，与G阳性相比，各指标均极显著降低，且降低的同时EJL水平升高，这与EJL中酚类和黄酮类化合物有关。在组织学结果中也发现了同样的效果。面包感官评价表明，这些叶子具有良好的适口性，可作为肝损伤的改善产品。
{"title":"Tetrachloromethane (CCl4)-induced liver deterioration in rats with effects of the phytochemical in loquat (Eriobotrya japonica) leaves","authors":"Dalia Hassan","doi":"10.21608/bnni.2022.271353","DOIUrl":"https://doi.org/10.21608/bnni.2022.271353","url":null,"abstract":": he fruit tree Eriobotrya japonica (EJL) performs a variety of essential functions. The current article's target was to establish the hepatoprotective effects of the phenolic and flavonoid constituents in loquat leaves (E. japonica); versus CCl4 in rats. In this study, thirty male albino rats averaging 190± 10 g were separated into two main sets: first G (-ve) was fed on a basal diet for 4 weeks and the remainder were injected by CCL 4 for induction liver injury twice weekly for 4 weeks, there are all treatment rats divided into 4 sub-groups. Second G was fed a basal diet with CCL 4 injection (2 mg /kg) (+ve) control and sets (3,4,5) fed different dried Eriobotrya japonica levels at (50,100 and 150 g/kg diet). The findings revealed that all indicators have highly significantly increased (malondialdehyde MDA, liver enzymes, lipid parameter) after CCL 4 injection, but when added EJL at different levels, all parameters were highly significantly decreased when compared with positive G, and the decreasing level was accompanied with increasing the EJL levels, this due to the phenolic and flavonoids compounds of EJL. The same effects were noticed in histological results. Bread sensory evaluation revealed the good palatability of these leaves, which could be used as ameliorating products for liver injury.","PeriodicalId":9493,"journal":{"name":"Bulletin of the National Nutrition Institute of the Arab Republic of Egypt","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88354137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-01DOI: 10.21608/bnni.2022.273591
M. Naeem
orn silk has traditionally been seen as a waste material, but in numerous areas around the world, it is used as a traditional medicine. The main objective of this study was to study the effects of corn silk (Zea mays L.) powder, ethanolic extract, and corn silk tea on protecting rats from kidney failure and liver injury and their action on pathogenic bacteria. Corn silk ethanolic extract had the highest total phenolic content and total flavonoid content. Seventeen kinds of phenolic were detected; Ferulic acid has the highest amount of phenolic content. The corn silk extracts showed excellent phytochemical and antioxidant activity. Additionally, they have strong antimicrobial properties. The biological experiment was carried out on thirty male rats weighing (200 ± 5 g) for six weeks and divided into five groups, one of which was a negative control (Basel diet) 2, 3, 4, and 5 groups were given gentamicin by injection to induce liver and kidney toxicity, (group2) was a Positive control and the 3, 4and5 groups were treated with different corn silk treatments. The result demonstrated that corn silk and its extract enhanced antioxidant enzymes using superoxide dismutase (SOD), and Total Antioxidant Capacity (TAC), Lipid peroxidation was evaluated as Malondialdehyde (MDA), liver functions, kidney functions, and histopathology of the kidneys when compared with the positive group. Finally, this study found that corn silk has antimicrobial activity against pathogenic microorganisms as well as renoprotective and hepatoprotective effects against gentamycin-induced hepato-nephrotoxicity.
{"title":"Protective effect of Corn silk (Zea mays L.) on kidney and liver functions of rats","authors":"M. Naeem","doi":"10.21608/bnni.2022.273591","DOIUrl":"https://doi.org/10.21608/bnni.2022.273591","url":null,"abstract":"orn silk has traditionally been seen as a waste material, but in numerous areas around the world, it is used as a traditional medicine. The main objective of this study was to study the effects of corn silk (Zea mays L.) powder, ethanolic extract, and corn silk tea on protecting rats from kidney failure and liver injury and their action on pathogenic bacteria. Corn silk ethanolic extract had the highest total phenolic content and total flavonoid content. Seventeen kinds of phenolic were detected; Ferulic acid has the highest amount of phenolic content. The corn silk extracts showed excellent phytochemical and antioxidant activity. Additionally, they have strong antimicrobial properties. The biological experiment was carried out on thirty male rats weighing (200 ± 5 g) for six weeks and divided into five groups, one of which was a negative control (Basel diet) 2, 3, 4, and 5 groups were given gentamicin by injection to induce liver and kidney toxicity, (group2) was a Positive control and the 3, 4and5 groups were treated with different corn silk treatments. The result demonstrated that corn silk and its extract enhanced antioxidant enzymes using superoxide dismutase (SOD), and Total Antioxidant Capacity (TAC), Lipid peroxidation was evaluated as Malondialdehyde (MDA), liver functions, kidney functions, and histopathology of the kidneys when compared with the positive group. Finally, this study found that corn silk has antimicrobial activity against pathogenic microorganisms as well as renoprotective and hepatoprotective effects against gentamycin-induced hepato-nephrotoxicity.","PeriodicalId":9493,"journal":{"name":"Bulletin of the National Nutrition Institute of the Arab Republic of Egypt","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84416135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-01DOI: 10.21608/bnni.2022.272048
Heba Abd Elhaliem, Baseem Zwain
his study was done to identify dietary factors that contribute to anemia in a sample of pregnant women in Cairo University Hospitals (Al-Qasr Al-Aini). This study was carried out on 200 anemic pregnant women in the first trimester of pregnancy, whose ages ranged from 21 to 25 years old. The participant's nutritional status was evaluated by daily diets and anthropometric measurements. The a nemic pregnant women were examined for ferritin, serum iron, and CBC test. The study showed that approximately 70% of pregnant women were overweight. 80% of the cases in this study did not suffer from any diseases, but 5% and 2.5% suffered from high blood pressure and diabetes respectively. 50% of them ate two meals and did not care about breakfast and ate fatty food. The majority of the anemic pregnant women had insufficient intake of protein, fiber, calcium, iron, zinc, vitamin D, vitamin B1, niacin, and vitamin B6 as compared with the RDA. These findings highlight the necessity for good nutritional intake both quantity and quality during pregnancy.
{"title":"Dietary Practices Linked to Anemia in Pregnant Women","authors":"Heba Abd Elhaliem, Baseem Zwain","doi":"10.21608/bnni.2022.272048","DOIUrl":"https://doi.org/10.21608/bnni.2022.272048","url":null,"abstract":"his study was done to identify dietary factors that contribute to anemia in a sample of pregnant women in Cairo University Hospitals (Al-Qasr Al-Aini). This study was carried out on 200 anemic pregnant women in the first trimester of pregnancy, whose ages ranged from 21 to 25 years old. The participant's nutritional status was evaluated by daily diets and anthropometric measurements. The a nemic pregnant women were examined for ferritin, serum iron, and CBC test. The study showed that approximately 70% of pregnant women were overweight. 80% of the cases in this study did not suffer from any diseases, but 5% and 2.5% suffered from high blood pressure and diabetes respectively. 50% of them ate two meals and did not care about breakfast and ate fatty food. The majority of the anemic pregnant women had insufficient intake of protein, fiber, calcium, iron, zinc, vitamin D, vitamin B1, niacin, and vitamin B6 as compared with the RDA. These findings highlight the necessity for good nutritional intake both quantity and quality during pregnancy.","PeriodicalId":9493,"journal":{"name":"Bulletin of the National Nutrition Institute of the Arab Republic of Egypt","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78599640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-01DOI: 10.21608/bnni.2022.279993
S. Saleh, Hanaa H. Elsayed, Hoda El Gezery, Asmaa S Mostafa
{"title":"Micronutrient Intake Profile of Egyptian Women in Reproductive Ages","authors":"S. Saleh, Hanaa H. Elsayed, Hoda El Gezery, Asmaa S Mostafa","doi":"10.21608/bnni.2022.279993","DOIUrl":"https://doi.org/10.21608/bnni.2022.279993","url":null,"abstract":"","PeriodicalId":9493,"journal":{"name":"Bulletin of the National Nutrition Institute of the Arab Republic of Egypt","volume":"144 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89225658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-01DOI: 10.21608/bnni.2022.277931
Gihan Ahmad, Hanna Abdel Wahab, Eman Elkronfoly, Fatma Rabie, Samah Mohamed, S. Mostafa, Shireen Sharaf
{"title":"Systematic Review 2022: Effect of probiotics versus herbal remedies on infantile colic","authors":"Gihan Ahmad, Hanna Abdel Wahab, Eman Elkronfoly, Fatma Rabie, Samah Mohamed, S. Mostafa, Shireen Sharaf","doi":"10.21608/bnni.2022.277931","DOIUrl":"https://doi.org/10.21608/bnni.2022.277931","url":null,"abstract":"","PeriodicalId":9493,"journal":{"name":"Bulletin of the National Nutrition Institute of the Arab Republic of Egypt","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90696072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-01DOI: 10.21608/bnni.2022.255461
Wafaa Abdel Hamid, A. Elmoslemany, Neveen M. Zeima
he current study was performed to evaluate the protective effect of aqueous extracts of Corn silk and Asparagus Officinalis against renal toxicity induced by formaldehyde in rats. Thirty-six male albino rats with "Sprague Dawley" strain weighing (150±10 g) were used and split into 2 major groups, the first group (6 rats) fed on a basal diet and kept as a negative control, and the second group of 30 rats was injected with formaldehyde intraperitoneally (10 mg/kg BW /day on 14 th to 28 th day and divided into 5 subgroups. The first subgroup received a normal diet and acted as a positive control group. The second, third, fourth, and fifth categories consumed standard feed with oral dosages of 200 and 400 mg/Kg body weight per day of aqueous corn silk and asparagus aqueous extract respectively during a 28-day period. Body weight gain (BWG), Feed intake (FI), feed efficiency ratio (FER), and relative kidney weight were computed at the finish of the experiment. Assessment of some serum biochemical parameters, kidney tissues were analyzed for antioxidant/oxidant markers, and histopathology of kidneys were assessed. The results revealed that corn silk and Asparagus aqueous extracts improved the biological evaluation, kidney functions, liver functions, Serum electrolytes, antioxidant enzymes activity, and histopathology of kidneys compared to the positive group. In conclusion, the administration of corn silk and Asparagus aqueous extracts can lower the impacts of formaldehyde on kidneys.
{"title":"The Potential Protective Effects of Aqueous Extracts of Some Herbs on Renal Toxicity Induced by Formaldehyde in Experimental Rats","authors":"Wafaa Abdel Hamid, A. Elmoslemany, Neveen M. Zeima","doi":"10.21608/bnni.2022.255461","DOIUrl":"https://doi.org/10.21608/bnni.2022.255461","url":null,"abstract":"he current study was performed to evaluate the protective effect of aqueous extracts of Corn silk and Asparagus Officinalis against renal toxicity induced by formaldehyde in rats. Thirty-six male albino rats with \"Sprague Dawley\" strain weighing (150±10 g) were used and split into 2 major groups, the first group (6 rats) fed on a basal diet and kept as a negative control, and the second group of 30 rats was injected with formaldehyde intraperitoneally (10 mg/kg BW /day on 14 th to 28 th day and divided into 5 subgroups. The first subgroup received a normal diet and acted as a positive control group. The second, third, fourth, and fifth categories consumed standard feed with oral dosages of 200 and 400 mg/Kg body weight per day of aqueous corn silk and asparagus aqueous extract respectively during a 28-day period. Body weight gain (BWG), Feed intake (FI), feed efficiency ratio (FER), and relative kidney weight were computed at the finish of the experiment. Assessment of some serum biochemical parameters, kidney tissues were analyzed for antioxidant/oxidant markers, and histopathology of kidneys were assessed. The results revealed that corn silk and Asparagus aqueous extracts improved the biological evaluation, kidney functions, liver functions, Serum electrolytes, antioxidant enzymes activity, and histopathology of kidneys compared to the positive group. In conclusion, the administration of corn silk and Asparagus aqueous extracts can lower the impacts of formaldehyde on kidneys.","PeriodicalId":9493,"journal":{"name":"Bulletin of the National Nutrition Institute of the Arab Republic of Egypt","volume":"192 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89086656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-01DOI: 10.21608/bnni.2022.275588
E. Fadlalla
: isphenol A (BPA), an endocrine-disrupting chemical, is widely used in industrial production. However, it is considered a ubiquitous environmental contaminant worldwide. Bisphenol-A acts like estrogen by interacting with the l estrogen receptors and is known to cause ovarian toxicity. The current investigation aimed to examine the effects of quercetin and melatonin on bisphenol-A–induced oxidative stress in ovarian and uterine tissues. Thirty-two female rats weighing (200±10 g) were divided into four groups. Group 1: intake standard diet; Group 2: bisphenol-A (120 mg/kg body weight) via oral gavage; Group 3: bisphenol-A (120 mg/kg body weight) + quercetin (50 mg/kg body weight via oral administration); and Group 4: bisphenol-A (120 mg/kg body weight) + melatonin (50 mg/kg body weight through oral). After a six-weeks experimental period, serum, ovaries, and uteruses were collected for hormonal analysis, ovarian and uterine analysis of oxidative stress biomarkers, and histopathological examination. The findings revealed that BPA decreased serum estradiol (E2) significantly. In addition, malondialdehyde (MDA) showed a significant increase. wheares ovarian and uterine antioxidant enzyme levels, including superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx), were significantly diminished histological abnormalities in the ovaries and uterus were observed in the BPA group. However, the administration of melatonin and quercitrin significantly inhibited the debilitating effects of BPA on the reproduction of female rats. Moreover, melatonin and quercetin exerted protective effects against oxidative stress caused by BPA. In a conclusion, both quercetin and melatonin had protective effects against BPA-induced ovarian and uterine oxidative stress.
{"title":"Effect of Quercetin and Melatonin on Bisphenol A–Induced Oxidative Stress in rats Ovarian and Uterine Tissues","authors":"E. Fadlalla","doi":"10.21608/bnni.2022.275588","DOIUrl":"https://doi.org/10.21608/bnni.2022.275588","url":null,"abstract":": isphenol A (BPA), an endocrine-disrupting chemical, is widely used in industrial production. However, it is considered a ubiquitous environmental contaminant worldwide. Bisphenol-A acts like estrogen by interacting with the l estrogen receptors and is known to cause ovarian toxicity. The current investigation aimed to examine the effects of quercetin and melatonin on bisphenol-A–induced oxidative stress in ovarian and uterine tissues. Thirty-two female rats weighing (200±10 g) were divided into four groups. Group 1: intake standard diet; Group 2: bisphenol-A (120 mg/kg body weight) via oral gavage; Group 3: bisphenol-A (120 mg/kg body weight) + quercetin (50 mg/kg body weight via oral administration); and Group 4: bisphenol-A (120 mg/kg body weight) + melatonin (50 mg/kg body weight through oral). After a six-weeks experimental period, serum, ovaries, and uteruses were collected for hormonal analysis, ovarian and uterine analysis of oxidative stress biomarkers, and histopathological examination. The findings revealed that BPA decreased serum estradiol (E2) significantly. In addition, malondialdehyde (MDA) showed a significant increase. wheares ovarian and uterine antioxidant enzyme levels, including superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx), were significantly diminished histological abnormalities in the ovaries and uterus were observed in the BPA group. However, the administration of melatonin and quercitrin significantly inhibited the debilitating effects of BPA on the reproduction of female rats. Moreover, melatonin and quercetin exerted protective effects against oxidative stress caused by BPA. In a conclusion, both quercetin and melatonin had protective effects against BPA-induced ovarian and uterine oxidative stress.","PeriodicalId":9493,"journal":{"name":"Bulletin of the National Nutrition Institute of the Arab Republic of Egypt","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84719488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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