首页 > 最新文献

中国实用医药最新文献

英文 中文
Interrelation between the structural-functional condition of myocardium and the activity of vascular-endothelial growth factor and blood inflammatory reaction in patients with pulmonary tuberculosis 肺结核患者心肌结构功能状况与血管内皮生长因子活性及血液炎症反应的关系
Pub Date : 2023-01-01 DOI: 10.32000/2072-1757-2022-3-2-85-90
D. Kolchin, V. Ruzov, L. N. Savonenkova
Taking into account the conflicting literature data on the frequency of the clinical form of pulmonary tuberculosis and its impact on the structural and functional state of the heart, an echocardiographic assessment of heart parameters was carried out in patients with pulmonary tuberculosis and its relationship with the vascular endothelial growth factor VEGF-A. The purpose — to evaluate the relationship between the structural and functional state of the myocardium and the concentration of VEGF in the blood serum in patients with pulmonary tuberculosis. Material and methods. The study included 77 patients with newly diagnosed pulmonary tuberculosis. During the study, the patients were randomized into 3 groups: group 1 — patients with an infiltrative form (n = 42), group 2 — patients with a disseminated form (n = 20), group 3 — patients with fibrous-cavernous form of pulmonary tuberculosis (n = 15). The control group consisted of 10 volunteers. B-mode echocardiography was performed and VEGF concentration was assessed by ELISA. Results. Higher values of RV length, LA area and RA area, and mean LA pressure were found in patients with fibrous-cavernous form, which is due to hypertrophy of the right heart, as indicated by higher values of wall thickness RV — 4.12 mm vs 3.70 in patients of the control group. A high concentration of VEGF-A in the blood serum is associated with higher parameters of erythrocyte sedimentation rate and platelet count, which may indicate a more pronounced systemic inflammatory response in the infiltrative form of pulmonary tuberculosis. Conclusion. Pulmonary tuberculosis is accompanied by structural and functional remodeling of the right and left parts of the heart, the severity of which is associated with the clinical form of the disease. The infiltrative form of pulmonary tuberculosis is associated with significantly higher values of the pro-inflammatory angiogenic cytokine VEGF-A compared to other clinical forms of tuberculosis and the control group.
考虑到肺结核临床形式的频率及其对心脏结构和功能状态的影响,文献资料相互矛盾,我们对肺结核患者的心脏参数进行了超声心动图评估及其与血管内皮生长因子VEGF-A的关系。目的:探讨肺结核患者心肌结构和功能状态与血清VEGF浓度的关系。材料和方法。该研究包括77例新诊断的肺结核患者。在研究过程中,患者被随机分为3组:1组浸润性肺结核患者(n = 42), 2组弥散性肺结核患者(n = 20), 3组纤维海绵状肺结核患者(n = 15)。对照组由10名志愿者组成。行b超心动图检查,ELISA检测VEGF浓度。结果。纤维-海绵状形态患者右心室长度、LA面积和RA面积以及平均LA压力值较高,这是由于右心脏肥大所致,如右心室壁厚度RV - 4.12 mm高于对照组的3.70 mm。血清中VEGF-A的高浓度与较高的红细胞沉降率和血小板计数相关,这可能表明浸润性肺结核有更明显的全身炎症反应。结论。肺结核伴有心脏左右部分的结构和功能重塑,其严重程度与该病的临床形式有关。与其他临床形式的结核病和对照组相比,浸润型肺结核与促炎血管生成细胞因子VEGF-A的值显著升高有关。
{"title":"Interrelation between the structural-functional condition of myocardium and the activity of vascular-endothelial growth factor and blood inflammatory reaction in patients with pulmonary tuberculosis","authors":"D. Kolchin, V. Ruzov, L. N. Savonenkova","doi":"10.32000/2072-1757-2022-3-2-85-90","DOIUrl":"https://doi.org/10.32000/2072-1757-2022-3-2-85-90","url":null,"abstract":"Taking into account the conflicting literature data on the frequency of the clinical form of pulmonary tuberculosis and its impact on the structural and functional state of the heart, an echocardiographic assessment of heart parameters was carried out in patients with pulmonary tuberculosis and its relationship with the vascular endothelial growth factor VEGF-A. The purpose — to evaluate the relationship between the structural and functional state of the myocardium and the concentration of VEGF in the blood serum in patients with pulmonary tuberculosis. Material and methods. The study included 77 patients with newly diagnosed pulmonary tuberculosis. During the study, the patients were randomized into 3 groups: group 1 — patients with an infiltrative form (n = 42), group 2 — patients with a disseminated form (n = 20), group 3 — patients with fibrous-cavernous form of pulmonary tuberculosis (n = 15). The control group consisted of 10 volunteers. B-mode echocardiography was performed and VEGF concentration was assessed by ELISA. Results. Higher values of RV length, LA area and RA area, and mean LA pressure were found in patients with fibrous-cavernous form, which is due to hypertrophy of the right heart, as indicated by higher values of wall thickness RV — 4.12 mm vs 3.70 in patients of the control group. A high concentration of VEGF-A in the blood serum is associated with higher parameters of erythrocyte sedimentation rate and platelet count, which may indicate a more pronounced systemic inflammatory response in the infiltrative form of pulmonary tuberculosis. Conclusion. Pulmonary tuberculosis is accompanied by structural and functional remodeling of the right and left parts of the heart, the severity of which is associated with the clinical form of the disease. The infiltrative form of pulmonary tuberculosis is associated with significantly higher values of the pro-inflammatory angiogenic cytokine VEGF-A compared to other clinical forms of tuberculosis and the control group.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83041213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stress echocardiography in the diagnosis of cardiac dysfunction in the early post-infarction period 应激超声心动图对梗死后早期心功能障碍的诊断价值
Pub Date : 2023-01-01 DOI: 10.32000/2072-1757-2023-4-102-107
A. M. Vorobev, V. Ruzov, M. A. Melnikova, V. A. Kadebina
The purpose — to assess the importance of stress echocardiography in identifying the nature and severity of cardiac dysfunction in patients with myocardial infarction. Material and methods.86 patients were examined at the outpatient stage of rehabilitation 6 weeks after myocardial infarction with primary coronary angioplasty with stenting. Results.Echocardiography revealed left ventricular hypertrophy (LVH) in 34 patients with myocardial infarction with concomitant arterial hypertension. Patients with LVH are characterized by more pronounced structural and functional LV remodeling, which is expressed in a lower LVEF and increased LVEDD, LVESVand LVEDV(p<0.05). There were no differences in stroke volume between patients with and without LVH. The performed diastolic stress test in patients with LVH is characterized by significantly lower average early diastolic mitral annular velocity e` (7.6 vs. 9.3 cm/s, p<0.01) without differences in the peak early transmitral Doppler flow velocity E (69.8 vs 78.0, p>0.05) compared with patients without LVH. The revealed differences between patients with and without LVH are due to a higher post-exercise velocity e` in patients with normal LV geometry and a decrease in eccentric LVH subgroup. Conclusions.1) Patients with LVH in the early postinfarction period (6 weeks) have more pronounced LV systolic dysfunction, expressed in a decrease in LVEF and an increase in LVEDD, LVESV, LVEDV compared to patients without LVH.2) Left ventricular hypertrophy, in conditions of myocardial infarction, is associated with latent diastolic dysfunction, which is manifested by a lower average early diastolic mitral annular velocity e` after the stress-test.
目的-评估应激超声心动图在识别心肌梗死患者心功能障碍的性质和严重程度中的重要性。材料和方法。86例患者在心肌梗死后6周的门诊康复期接受检查。结果。超声心动图显示34例心肌梗死合并动脉高压患者左心室肥厚。与无LVH患者相比,LVH患者结构和功能重构更为明显,表现为LVEF降低,LVEDD、LVESVand LVEDV升高(p0.05)。有LVH和没有LVH的患者之间的差异是由于正常左室几何形状的患者运动后速度e '更高,而偏心LVH亚组减少。结论:1)梗死后早期(6周)LVH患者左室收缩功能障碍较无LVH患者更为明显,表现为LVEF降低,LVEDD、LVESV、LVEDV升高。2)心肌梗死条件下,左室肥厚与潜伏性舒张功能障碍相关,表现为压力测试后平均舒张早期二尖瓣环速度e′降低。
{"title":"Stress echocardiography in the diagnosis of cardiac dysfunction in the early post-infarction period","authors":"A. M. Vorobev, V. Ruzov, M. A. Melnikova, V. A. Kadebina","doi":"10.32000/2072-1757-2023-4-102-107","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-4-102-107","url":null,"abstract":"The purpose — to assess the importance of stress echocardiography in identifying the nature and severity of cardiac dysfunction in patients with myocardial infarction. Material and methods.86 patients were examined at the outpatient stage of rehabilitation 6 weeks after myocardial infarction with primary coronary angioplasty with stenting. Results.Echocardiography revealed left ventricular hypertrophy (LVH) in 34 patients with myocardial infarction with concomitant arterial hypertension. Patients with LVH are characterized by more pronounced structural and functional LV remodeling, which is expressed in a lower LVEF and increased LVEDD, LVESVand LVEDV(p<0.05). There were no differences in stroke volume between patients with and without LVH. The performed diastolic stress test in patients with LVH is characterized by significantly lower average early diastolic mitral annular velocity e` (7.6 vs. 9.3 cm/s, p<0.01) without differences in the peak early transmitral Doppler flow velocity E (69.8 vs 78.0, p>0.05) compared with patients without LVH. The revealed differences between patients with and without LVH are due to a higher post-exercise velocity e` in patients with normal LV geometry and a decrease in eccentric LVH subgroup. Conclusions.1) Patients with LVH in the early postinfarction period (6 weeks) have more pronounced LV systolic dysfunction, expressed in a decrease in LVEF and an increase in LVEDD, LVESV, LVEDV compared to patients without LVH.2) Left ventricular hypertrophy, in conditions of myocardial infarction, is associated with latent diastolic dysfunction, which is manifested by a lower average early diastolic mitral annular velocity e` after the stress-test.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"79 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83780339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feto-maternal microchimerism: a cause of preeclampsia? The role of trophoblast in the prognosis of pregnancy complicated by preeclampsia 胎母微嵌合:子痫前期的原因?滋养细胞在妊娠合并子痫前期预后中的作用
Pub Date : 2023-01-01 DOI: 10.32000/2072-1757-2023-3-29-35
A. Khasanov, A. V. Arzamastseva, I. Raginov
Preeclampsia is one of the most important problems in obstetrics. Every year, preeclampsia affects 6–8% of pregnant women in developed countries and over 20% pregnant women in developing countries. It is noted that together with obstetric bleeding and infectious complications, preeclampsia constitutes the so-called «deadly triad» and is the cause of the overwhelming number of maternal deaths. The possibilities of treating preeclampsia are limited only to symptomatic therapy, and in the absence of the desired effect, the patient is offered delivery. To date, new, pathogenetically determined, methods of treatment aimed at inhibiting the activity of membrane-attacking molecules are being considered. This literature review provides information on the role of the trophoblast in the pathogenesis of preeclampsia. The increase in the concentration of trophoblast cells in the mother’s blood leads to excessive activation of the complement system, which causes multiple endothelial damage, leading to multiple organ failure.
先兆子痫是产科最重要的问题之一。每年,先兆子痫影响发达国家6-8%的孕妇和发展中国家20%以上的孕妇。委员会指出,先兆子痫与产科出血和感染性并发症一起构成了所谓的"致命的三位一体",是造成绝大多数产妇死亡的原因。治疗先兆子痫的可能性仅限于对症治疗,在没有预期效果的情况下,患者被提供分娩。迄今为止,新的,病理确定的,旨在抑制膜攻击分子活性的治疗方法正在考虑。本文综述了滋养细胞在子痫前期发病机制中的作用。母体血液中滋养细胞浓度升高,导致补体系统过度激活,造成多重内皮损伤,导致多器官功能衰竭。
{"title":"Feto-maternal microchimerism: a cause of preeclampsia? The role of trophoblast in the prognosis of pregnancy complicated by preeclampsia","authors":"A. Khasanov, A. V. Arzamastseva, I. Raginov","doi":"10.32000/2072-1757-2023-3-29-35","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-3-29-35","url":null,"abstract":"Preeclampsia is one of the most important problems in obstetrics. Every year, preeclampsia affects 6–8% of pregnant women in developed countries and over 20% pregnant women in developing countries. It is noted that together with obstetric bleeding and infectious complications, preeclampsia constitutes the so-called «deadly triad» and is the cause of the overwhelming number of maternal deaths. The possibilities of treating preeclampsia are limited only to symptomatic therapy, and in the absence of the desired effect, the patient is offered delivery. To date, new, pathogenetically determined, methods of treatment aimed at inhibiting the activity of membrane-attacking molecules are being considered. This literature review provides information on the role of the trophoblast in the pathogenesis of preeclampsia. The increase in the concentration of trophoblast cells in the mother’s blood leads to excessive activation of the complement system, which causes multiple endothelial damage, leading to multiple organ failure.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83839270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adenomyosis and endometriosis: common features 子宫腺肌病和子宫内膜异位症:共同特征
Pub Date : 2023-01-01 DOI: 10.32000/2072-1757-2023-4-37-40
R. Gabidullina, F. F. Minnullina, T. N. Shigabutdinova, D. I. Akhmetova, A. Zaripova, S. I. Kharitonova
The purpose — to summarize the results of molecular genetic studies of adenomyosis and endometriosis. Material and methods. Review of publications based on search results in the electronic resources PubMed, Elibrary, EMBASE and Google Scholar. Results. Marked differences between endometriosis and adenomyosis in pathogenesis, lesion localisation and clinical features have led to the recognition of adenomyosis as a separate clinical entity. In the new International Classification of Diseases 11th Revision, adenomyosis was removed from the section «Endometriosis» (GA10) and presented as a separate disease «Adenomyosis». Identical KRAS mutations in epithelial cells in endometriosis, adenomyosis and combined endometriosis suggest that adenomyosis and endometriosis are oligoclonal lesions arising from populations of cells of the basal layer of the endometrium carrying a specific driver mutation. Medication strategies that block ovarian steroidogenesis, as well as local estrogen synthesis, are a long-term treatment option for these chronic diseases. Conclusion. The results of molecular genetic studies indicate that endometriosis and adenomyosis are related conditions with a common molecular etiology.
目的综述子宫腺肌症和子宫内膜异位症的分子遗传学研究成果。材料和方法。根据电子资源PubMed, library, EMBASE和Google Scholar的搜索结果对出版物进行审查。结果。子宫内膜异位症和子宫腺肌症在发病机制、病变定位和临床特征上的显著差异,导致子宫腺肌症被视为一个独立的临床实体。在新的国际疾病分类第11次修订中,腺肌病从“子宫内膜异位症”(GA10)部分中删除,并作为一个单独的疾病“腺肌病”呈现。子宫内膜异位症、子宫腺肌症和合并子宫内膜异位症上皮细胞中相同的KRAS突变表明,子宫腺肌症和子宫内膜异位症是由携带特定驱动突变的子宫内膜基底层细胞群引起的寡克隆病变。阻断卵巢类固醇生成以及局部雌激素合成的药物策略是这些慢性疾病的长期治疗选择。结论。分子遗传学研究结果表明,子宫内膜异位症和子宫腺肌症是具有共同分子病因的相关疾病。
{"title":"Adenomyosis and endometriosis: common features","authors":"R. Gabidullina, F. F. Minnullina, T. N. Shigabutdinova, D. I. Akhmetova, A. Zaripova, S. I. Kharitonova","doi":"10.32000/2072-1757-2023-4-37-40","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-4-37-40","url":null,"abstract":"The purpose — to summarize the results of molecular genetic studies of adenomyosis and endometriosis. Material and methods. Review of publications based on search results in the electronic resources PubMed, Elibrary, EMBASE and Google Scholar. Results. Marked differences between endometriosis and adenomyosis in pathogenesis, lesion localisation and clinical features have led to the recognition of adenomyosis as a separate clinical entity. In the new International Classification of Diseases 11th Revision, adenomyosis was removed from the section «Endometriosis» (GA10) and presented as a separate disease «Adenomyosis». Identical KRAS mutations in epithelial cells in endometriosis, adenomyosis and combined endometriosis suggest that adenomyosis and endometriosis are oligoclonal lesions arising from populations of cells of the basal layer of the endometrium carrying a specific driver mutation. Medication strategies that block ovarian steroidogenesis, as well as local estrogen synthesis, are a long-term treatment option for these chronic diseases. Conclusion. The results of molecular genetic studies indicate that endometriosis and adenomyosis are related conditions with a common molecular etiology.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84073944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
History of the development of the hemodialysis service in the Republic of Tatarstan 鞑靼斯坦共和国血液透析服务的发展历史
Pub Date : 2023-01-01 DOI: 10.32000/2072-1757-2023-3-8-13
N. R. Gatiyatullin, A. Maksudova, M. Khasanova, M. D. Trofimova
The article provides information on the formation of hemodialysis service in the Republic of Tatarstan, starting from the first Russian «artificial kidney» model, the first arterio-venous shunt and dialyzer to the present day.
本文提供了鞑靼斯坦共和国血液透析服务的形成信息,从俄罗斯第一个“人工肾脏”模型,第一个动静脉分流器和透析器到今天。
{"title":"History of the development of the hemodialysis service in the Republic of Tatarstan","authors":"N. R. Gatiyatullin, A. Maksudova, M. Khasanova, M. D. Trofimova","doi":"10.32000/2072-1757-2023-3-8-13","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-3-8-13","url":null,"abstract":"The article provides information on the formation of hemodialysis service in the Republic of Tatarstan, starting from the first Russian «artificial kidney» model, the first arterio-venous shunt and dialyzer to the present day.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88315184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical treatment of neovaginal prolapse in a patient with Mayer — Rokitansky — Kuster — Hauser syndrome (clinical case) Mayer - Rokitansky - Kuster - Hauser综合征新发阴道脱垂的手术治疗(附临床一例)
Pub Date : 2023-01-01 DOI: 10.32000/2072-1757-2023-1-96-98
E. R. Mekhtieva, A. G. Yashchuk, I. Musin, E. Popova, A. G. Imelbayeva, A. Tyurina
The article describes a case of complications after surgical treatment of a patient with Mayer — Rokitansky — Kuster — Hauser syndrome, which is characterized by underdevelopment of the Muller ducts derivatives in girls and is manifested by malformations of the vagina and uterus. The features of the diagnosis and surgical treatment of complications using the latest endoscopic techniques are also described.
本文描述了一例手术治疗后的并发症患者与Mayer - Rokitansky - Kuster - Hauser综合征,其特点是穆勒管衍生物发育不全的女孩,表现为阴道和子宫畸形。使用最新的内窥镜技术诊断和手术治疗并发症的特点也被描述。
{"title":"Surgical treatment of neovaginal prolapse in a patient with Mayer — Rokitansky — Kuster — Hauser syndrome (clinical case)","authors":"E. R. Mekhtieva, A. G. Yashchuk, I. Musin, E. Popova, A. G. Imelbayeva, A. Tyurina","doi":"10.32000/2072-1757-2023-1-96-98","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-1-96-98","url":null,"abstract":"The article describes a case of complications after surgical treatment of a patient with Mayer — Rokitansky — Kuster — Hauser syndrome, which is characterized by underdevelopment of the Muller ducts derivatives in girls and is manifested by malformations of the vagina and uterus. The features of the diagnosis and surgical treatment of complications using the latest endoscopic techniques are also described.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89134711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical case of infliximab induction in a patient with Crohn’s disease and acute new coronavirus infection 英夫利昔单抗诱导克罗恩病合并急性新型冠状病毒感染1例临床观察
Pub Date : 2023-01-01 DOI: 10.32000/2072-1757-2023-3-121-124
D. Mukhametova, E. Bodryagina, A. Odintsova, L. Kupkenova, D. F. Shafikova, B. M. Fontenelle, D. Abdulganieva
The article presents a clinical case of a new coronavirus infection in a patient with CD. The onset of the viral infection occurred during severe exacerbation of CD, what led to induction of infliximab therapy. The difficulty of managing patients with COVID-19 and immunoinflammatory diseases is discussed.
本文报道了一例新型冠状病毒感染的CD患者的临床病例。该病毒感染发生在CD严重恶化期间,导致诱导英夫利昔单抗治疗。讨论了COVID-19合并免疫炎性疾病患者管理的难点。
{"title":"Clinical case of infliximab induction in a patient with Crohn’s disease and acute new coronavirus infection","authors":"D. Mukhametova, E. Bodryagina, A. Odintsova, L. Kupkenova, D. F. Shafikova, B. M. Fontenelle, D. Abdulganieva","doi":"10.32000/2072-1757-2023-3-121-124","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-3-121-124","url":null,"abstract":"The article presents a clinical case of a new coronavirus infection in a patient with CD. The onset of the viral infection occurred during severe exacerbation of CD, what led to induction of infliximab therapy. The difficulty of managing patients with COVID-19 and immunoinflammatory diseases is discussed.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"107 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86255648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deventer’s pelvis, «gate of life» and the aggressive management of childbirth at the present time. Сlinical observation Deventer 's骨盆,“生命之门”和目前积极的分娩管理。Сlinical观察
Pub Date : 2023-01-01 DOI: 10.32000/2072-1757-2023-3-75-79
A. Khasanov, F. F. Minullina
In modern obstetrics, aggressive technologies are often used in the management of childbirth, the harm of which was mentioned by Hendrik van Deventer. The founder of classical obstetrics, born in Holland in 1651 and working during the epoch of obstetrics renaissance, Deventer wrote eight books popular till today. Deventer was an active opponent of aggressive obstetrics — he did not use obstetric forceps, nor the vacuum extraction of the fetus that was emerging at that time. He was the first to give a detailed description of the pelvis and to suggest that the shape and size of the pelvic bone could cause difficulties in childbirth. His instructions — to change the position of a woman in labor with pathological insertions of the fetal head are widely used by modern obstetricians. The term «Deventer’s pelvis» went down in the history of obstetrics – a simple flat pelvis, in which all direct dimensions are reduced (the planes of the entrance, cavity and exit of the pelvis). One of the varieties of Deventer’s pelvis is a reduction of only the direct size of the wide part of the pelvic cavity (with all other normal pelvic sizes), which occurs in 15–18% of all pregnant women. The presented clinical observation shows how the use of the Kristeller’s technique with a delayed fetal head can lead to severe traumatic complications in both the mother and the fetus. The authors recommend measuring the pubic-sacral size, which shows the size of the sacral cavity, to all pregnant women.
在现代产科中,侵略性技术经常用于分娩管理,其危害被Hendrik van Deventer提到。德文特尔是古典产科的创始人,1651年出生于荷兰,在产科复兴时期工作,他写了八本书,直到今天仍然很受欢迎。Deventer是激进产科的积极反对者——他不使用产钳,也不使用当时正在出现的胎儿的真空抽吸。他是第一个详细描述骨盆的人,并提出骨盆骨的形状和大小可能导致分娩困难。他的指示-改变产妇的位置,病理插入胎儿的头被现代产科医生广泛使用。“Deventer’s骨盆”一词在产科的历史上被记载下来——一种简单的扁平骨盆,所有的直接尺寸都缩小了(骨盆的入口、腔和出口的平面)。德文特氏骨盆的一种类型是盆腔宽部的直接缩小(与所有其他正常的盆腔大小一样),发生在所有孕妇的15-18%。目前的临床观察显示,如何使用Kristeller的技术与延迟胎头可导致严重的创伤并发症,在母亲和胎儿。作者建议所有孕妇测量耻骨-骶骨大小,这显示了骶骨腔的大小。
{"title":"Deventer’s pelvis, «gate of life» and the aggressive management of childbirth at the present time. Сlinical observation","authors":"A. Khasanov, F. F. Minullina","doi":"10.32000/2072-1757-2023-3-75-79","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-3-75-79","url":null,"abstract":"In modern obstetrics, aggressive technologies are often used in the management of childbirth, the harm of which was mentioned by Hendrik van Deventer. The founder of classical obstetrics, born in Holland in 1651 and working during the epoch of obstetrics renaissance, Deventer wrote eight books popular till today. Deventer was an active opponent of aggressive obstetrics — he did not use obstetric forceps, nor the vacuum extraction of the fetus that was emerging at that time. He was the first to give a detailed description of the pelvis and to suggest that the shape and size of the pelvic bone could cause difficulties in childbirth. His instructions — to change the position of a woman in labor with pathological insertions of the fetal head are widely used by modern obstetricians. The term «Deventer’s pelvis» went down in the history of obstetrics – a simple flat pelvis, in which all direct dimensions are reduced (the planes of the entrance, cavity and exit of the pelvis). One of the varieties of Deventer’s pelvis is a reduction of only the direct size of the wide part of the pelvic cavity (with all other normal pelvic sizes), which occurs in 15–18% of all pregnant women. The presented clinical observation shows how the use of the Kristeller’s technique with a delayed fetal head can lead to severe traumatic complications in both the mother and the fetus. The authors recommend measuring the pubic-sacral size, which shows the size of the sacral cavity, to all pregnant women.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"97 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81410371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Consequences of accidental intra-arterial administration of bicillin — Hoigne syndrome 意外动脉内给药比西林- Hoigne综合征的后果
Pub Date : 2023-01-01 DOI: 10.32000/2072-1757-2023-3-130-133
A. Z. Nigmedzyanova, L. Kulagina, E. R. Kadyseva, R. V. Davletshina
The article presents a description of a rare clinical case of consequences of accidental intra-arterial administration of bicillin with the development of Hoigne syndrome.
本文介绍了一个罕见的临床病例的后果意外动脉内给药比西林与Hoigne综合征的发展。
{"title":"Consequences of accidental intra-arterial administration of bicillin — Hoigne syndrome","authors":"A. Z. Nigmedzyanova, L. Kulagina, E. R. Kadyseva, R. V. Davletshina","doi":"10.32000/2072-1757-2023-3-130-133","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-3-130-133","url":null,"abstract":"The article presents a description of a rare clinical case of consequences of accidental intra-arterial administration of bicillin with the development of Hoigne syndrome.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"98 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79161125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combination of congenital malformation of the gastrointestinal tract and kidneys: a clinical case 先天性胃肠道及肾脏合并畸形1例
Pub Date : 2023-01-01 DOI: 10.32000/2072-1757-2022-4-123-125
S. V. Aborin, D. V. Pechkurov, A. V. Varlamov, A. V. Maznova, N. V. Sviridova
Currently, the correction of congenital malformations in children is one of the important tasks of modern medicine. If a radical correction of the defect is performed timely, the child will grow up healthy. Combinations of congenital malformations create serious difficulties for clinicians and require the participation of a multidisciplinary team, combining various approaches and methods. The article presents a clinical case of a newborn child with atresia of the ileum, hypoplasia of the aortic arch and bilateral hypoplasia of the kidneys. Since birth, the child’s condition was complicated by the development of shock and subsequent azotemia, hyperhydration. Since the correction of atresia could not be postponed for a long time, it was decided to perform implantation of a peritoneal catheter during surgery on the intestine in case of a repeat episode of acute kidney injury. The presented clinical case demonstrates the possibility of renal replacement therapy in patients after surgery in the abdominal cavity.
目前,儿童先天性畸形的矫治是现代医学的重要任务之一。如果及时根治缺陷,孩子将健康成长。先天性畸形的组合给临床医生带来了严重的困难,需要多学科团队的参与,结合各种途径和方法。本文报告一新生儿回肠闭锁、主动脉弓发育不全及双侧肾脏发育不全的临床病例。自出生以来,孩子的病情因休克和随后的氮质血症、水合过度而变得复杂。由于闭锁的矫正不能拖太久,所以决定手术中在肠上植入腹膜导尿管,以防急性肾损伤反复发作。本临床病例证明了在腹腔手术后患者进行肾脏替代治疗的可能性。
{"title":"Combination of congenital malformation of the gastrointestinal tract and kidneys: a clinical case","authors":"S. V. Aborin, D. V. Pechkurov, A. V. Varlamov, A. V. Maznova, N. V. Sviridova","doi":"10.32000/2072-1757-2022-4-123-125","DOIUrl":"https://doi.org/10.32000/2072-1757-2022-4-123-125","url":null,"abstract":"Currently, the correction of congenital malformations in children is one of the important tasks of modern medicine. If a radical correction of the defect is performed timely, the child will grow up healthy. Combinations of congenital malformations create serious difficulties for clinicians and require the participation of a multidisciplinary team, combining various approaches and methods. The article presents a clinical case of a newborn child with atresia of the ileum, hypoplasia of the aortic arch and bilateral hypoplasia of the kidneys. Since birth, the child’s condition was complicated by the development of shock and subsequent azotemia, hyperhydration. Since the correction of atresia could not be postponed for a long time, it was decided to perform implantation of a peritoneal catheter during surgery on the intestine in case of a repeat episode of acute kidney injury. The presented clinical case demonstrates the possibility of renal replacement therapy in patients after surgery in the abdominal cavity.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75553429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
中国实用医药
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1