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ChemInform Abstract: Isolation of Lingzhifuran A and Lingzhilactones D—F from Ganoderma lucidum as Specific Smad3 Phosphorylation Inhibitors and Total Synthesis of Lingzhifuran A. 摘要:灵芝呋喃A和灵芝内酯D-F作为Smad3特异性磷酸化抑制剂的分离及灵芝呋喃A的全合成。
ChemInform
Pub Date : 2016-12-06 DOI: 10.1002/chin.201652385
Wei-Yi Ding, Jun Ai, Xin-Long Wang, Fayang G. Qiu, Qing Lv, Ping Fang, Fan-Fan Hou, Yong-Ming Yan, Yong-Xian Cheng

The four new phenolic meroterpenoids, lingzhifuran A (I) and lingzhilactones D—F (II—IV), show inhibitory activities against transforming growth factor-β1-induced Smad3 phosphorylation.

四种新的酚类萜类化合物灵芝呋喃A (I)和灵芝内酯D-F (II-IV)对转化生长因子-β1诱导的Smad3磷酸化具有抑制作用。
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引用次数: 0
ChemInform Abstract: Increasing the Impact of Materials in and Beyond Bio-Nano Science 增加材料在生物纳米科学内外的影响
ChemInform
Pub Date : 2016-12-06 DOI: 10.1002/chin.201652501
Mattias Bjoernmalm, Matthew Faria, Frank Caruso

Review: 130 refs.

回顾:130人。
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引用次数: 7
ChemInform Abstract: Novel One-Pot Synthesis of Symmetrically Substituted Ureas. 摘要:一锅法合成对称取代脲的新方法。
ChemInform
Pub Date : 2016-12-06 DOI: 10.1002/chin.201652166
Xingxing Wu, Qingfen Niu, Tianduo Li

The simple and environmentally friendly protocol proceeds with inexpensive reagents.

该方法简单、环保，所用试剂价格低廉。
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引用次数: 0
ChemInform Abstract: Clindanones A and B and Cladosporols F and G, Polyketides from the Deep-Sea Derived Fungus Cladosporium cladosporioides HDN14-342. 摘要:深海衍生真菌Cladosporium cladosporioides HDN14-342的Clindanones A、B和cladsporols F、G多酮类化合物。
ChemInform
Pub Date : 2016-12-06 DOI: 10.1002/chin.201652419
Zhenzhen Zhang, Xueqian He, Congcong Liu, Qian Che, Tianjiao Zhu, Qianqun Gu, Dehai Li

Cladosporol G (I), together with another three new tetralone derivatives and three known biogenetically related polyketides, is isolated from title deep-sea derived fungus and is shown to have the best cytotoxic activity against HeLa cells with an IC50 value of 3.9 μM.

Cladosporol G (I)与另外3个新的四肽衍生物和3个已知的生物遗传学相关的聚酮化合物一起从深海真菌中分离得到，对HeLa细胞具有最佳的细胞毒活性，IC50值为3.9 μM。
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引用次数: 0
ChemInform Abstract: Synthesis of (1H-Pyrrol-1-yl)anthracene-9,10-diones. 摘要:(1h -吡咯-1-基)蒽-9,10-二酮的合成。
ChemInform
Pub Date : 2016-12-06 DOI: 10.1002/chin.201652217
Viktor I. Zvarych, Maryna V. Stasevych, Volodymyr V. Lunin, Mykhailo V. Vovk, Volodymyr P. Novikov

The title compounds are prepared from (amino)anthracenediones and (dimethoxy)tetrahydrofuran via Clauson—Kaas reaction using I2 as catalyst.

以(氨基)蒽二酮和(二甲氧基)四氢呋喃为原料，以I2为催化剂，通过Clauson-Kaas反应制备了标题化合物。
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引用次数: 1
ChemInform Abstract: Few-Layer Antimonene by Liquid-Phase Exfoliation. 摘要:液相剥离法制备少层锑烯。
ChemInform
Pub Date : 2016-12-06 DOI: 10.1002/chin.201652019
Gonzalo Abellan,  et al.

Highly stable iPrOH/H2O (4:1) suspensions of few-layer antimonene (FL-Sb) are prepared by liquid-phase exfoliation of ground Sb crystals via sonication without the need for surfactants (400 W, 24 kHz, 40 min).

在不需要表面活性剂(400 W, 24 kHz, 40 min)的情况下，通过超声对地面Sb晶体进行液相剥离，制备了高度稳定的iPrOH/H2O(4:1)少层锑烯(FL-Sb)悬浮液。
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引用次数: 5
ChemInform Abstract: The First Solvent-Free Synthesis of Privileged γ- and δ-Lactams via the Castagnoli—Cushman Reaction. 摘要:首次利用Castagnoli-Cushman反应无溶剂合成γ-和δ-内酰胺类化合物。
ChemInform
Pub Date : 2016-12-06 DOI: 10.1002/chin.201652301
Anastasia Lepikhina, Olga Bakulina, Dmitry Dar'in, Mikhail Krasavin

36 examples

36例子
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引用次数: 1
ChemInform Abstract: Visible-Light Photoredox-Catalyzed Coupling Reaction of Azoles with α-Carbamoyl Sulfides. 摘要:可见光光氧化催化氮唑与α-氨基甲酰硫化物的偶联反应。
ChemInform
Pub Date : 2016-12-06 DOI: 10.1002/chin.201652260
Lucie Jarrige, Guillaume Levitre, Geraldine Masson
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引用次数: 0
ChemInform Abstract: Simple Primary Amino Amide Organocatalyst for Enantioselective Aldol Reactions of Isatins with Ketones. 摘要:鸢尾素与酮类对映选择性醛醇反应的简单一级氨基酰胺有机催化剂。
ChemInform
Pub Date : 2016-12-06 DOI: 10.1002/chin.201652223
Eunsang Kwon,  et al.

Among a number of amino acid amide-derived organocatalysts, L-tert-leucine derivative TLA features best efficiency in terms of yield, dia- and enantiostereoselectivities in the title reaction, in particular, when 6-membered saturated (hetero)cyclic ketones are used.

在许多氨基酸酰胺衍生的有机催化剂中，l -叔亮氨酸衍生物TLA在反应中的产率、对映立体选择性和对映立体选择性方面具有最佳效率，特别是当使用6元饱和(杂)环酮时。
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引用次数: 0
ChemInform Abstract: Indoline-Based Constrained Peptidomimetic Motifs Obtained via the Joullie—Ugi Reaction of Indolenines. 摘要:通过吲哚啉的Joullie-Ugi反应获得了基于吲哚啉的受限拟肽基序。
ChemInform
Pub Date : 2016-12-06 DOI: 10.1002/chin.201652222
Pavel Golubev, Olga Bakulina, Dmitry Dar'in, Mikhail Krasavin

Sterically demanding indolenines are employed as cyclic imine substrates in the title reaction with isocyanides and carboxylic acids, resulting in a new type of conformationally constrained indoline-based peptidomimetics.

立体要求高的吲哚胺作为环亚胺底物与异氰酸酯和羧酸进行标题反应，得到了一种新型构象约束的吲哚基拟肽。
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引用次数: 0
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