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Clinical case: observation of a child with Chediak-Higashi syndrome 临床病例:1例Chediak-Higashi综合征患儿观察
Pub Date : 2023-04-01 DOI: 10.22627/2072-8107-2023-22-1-62-65
L. U. Ulukhanova, D. C. Amirkhanova, S. M. Attaeva, M. A. Ninalalov, N. C. Karnaeva
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引用次数: 0
Vaccination of children against COVID-19: foreign experience (literature review) 儿童COVID-19疫苗接种:国外经验(文献综述)
Pub Date : 2023-04-01 DOI: 10.22627/2072-8107-2023-22-1-45-49
A. Bufetova, A. Vishnyakov, E. Gorelov, E. Leushina, E. Utenkova
The need to vaccinate children under the age of 12 against COVID-19 remains an object of discussion today. The relatively low risk associated with infection in children and the ambiguous conclusions when comparing the effects of vaccination and the transferred disease are grounds to believe that the ratio of risk and benefit of vaccination in this age group is more complex. One of the key arguments in favor of vaccinating healthy children is to protect them from the long-term effects of COVID-19. In addition, socially significant factors such as a decrease in the spread of infection, the cost of vaccine supplies or damage associated with the organization of quarantine measures (including the closure of schools and the transfer of the educational process to a remote format) should be taken into account. The dynamics of the situation requires a constant reassessment of the risk and benefits of specific prevention in children. The purpose of this literature review is to systematize objective data concerning the foreign experience of vaccination of children against COVID-19;arguments for and against vaccination, which complicate the decision-making on the issue under study at one level or another.Copyright © 2023 The authors.
为12岁以下儿童接种COVID-19疫苗的必要性今天仍然是讨论的对象。与儿童感染相关的相对较低的风险以及在比较疫苗接种效果和转移疾病时得出的模棱两可的结论,使我们有理由相信,在这一年龄组中,疫苗接种的风险和益处的比例更为复杂。支持为健康儿童接种疫苗的关键论点之一是保护他们免受COVID-19的长期影响。此外,还应考虑到具有重要社会意义的因素,如感染传播的减少、疫苗供应的成本或与组织隔离措施(包括关闭学校和将教育过程转移到远程形式)有关的损害。形势的变化要求不断重新评估对儿童进行具体预防的风险和益处。本文献综述的目的是整理有关国外儿童接种COVID-19疫苗经验的客观数据;支持和反对接种疫苗的论据,这些论据在一个或另一个层面上使所研究问题的决策复杂化。版权所有©2023作者。
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引用次数: 0
Resistance to antibacterial drugs and bacteriophages of Klebsiella pneumoniae isolates isolated from children of different ages with intestinal infections 不同年龄儿童肠道感染肺炎克雷伯菌分离株对抗菌药物和噬菌体的耐药性
Pub Date : 2023-04-01 DOI: 10.22627/2072-8107-2023-22-1-27-31
N. V. Gonchar, A. K. Kopersak, N. Skripchenko, A. S. Kvetnaya, A. M. Moskalyuk, K. Ermolenko, E. Ermolenko, S. G. Grigor'ev
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引用次数: 0
Awareness of Russian tourists traveling to tropical and equatorial countries about the prevention of infectious diseases during travel 提高前往热带和赤道国家旅游的俄罗斯游客在旅行中预防传染病的意识
Pub Date : 2023-04-01 DOI: 10.22627/2072-8107-2023-22-1-19-26
N. N. Zverevа, E. Pylaeva, A. A. Erovichenkov, M. A. Sayfullin, T. N. Elagina, V. Tovstik, R. F. Sayfullin, N. Antipyat, O. Shamsheva
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引用次数: 0
Comparative characteristics of the bacterial microflora of the umbilical cord in newborn children 新生儿脐带细菌菌群的比较特点
Pub Date : 2023-04-01 DOI: 10.22627/2072-8107-2023-22-1-37-40
L. Bochkova, A. Eiberman, Y. Chernenkov, O. Kirilochev, Z. Tarasova
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引用次数: 0
Viral intestinal infections in young children in Baku 巴库幼儿的病毒性肠道感染
Pub Date : 2023-04-01 DOI: 10.22627/2072-8107-2023-22-1-41-44
F. V. Qilindjova
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引用次数: 0
Correlations of interleukin levels with the severity of SARS-CoV-2 coronavirus infection 白细胞介素水平与SARS-CoV-2冠状病毒感染程度的相关性
Pub Date : 2023-03-31 DOI: 10.22627/2072-8107-2023-22-1-11-13
O. N. Yashkina, N. G. Tsareva, O. Borisova
A new coronavirus infection caused by the SARS-CoV-2 virus is characterized by a systemic hyperinflammatory response with a pronounced increase in the content of pro-inflammatory cytokines. Materials and methods. The study was conducted on the basis of the Samara Regional Children's Infectious Diseases Hospital from 2021 to 2022. 40 patients with moderate (n = 20, group I) and severe forms (n = 20, group II) COVID-19 were studied, the comparison group consisted of patients with viral pneumonia of another etiology (n = 35, group III). Results. The infectious agent SARS-CoV-2 induces high levels of cytokines IL-6 (p < 0.005), IL-8 (p < 0.05) and a slight increase in TNF-alpha (p < 0.05). IL-8 was significantly associated with disease duration (p < 0.01). We assume that the value of this interleukin will increase in the post-COVID period. Conclusions. Changes in IL-6 and IL-8 levels in patients with COVID-19, along with clinical features, are important biomarkers for predicting the severity and duration of the disease.Copyright © Children Infections.All rights reserved
由SARS-CoV-2病毒引起的新型冠状病毒感染的特征是全身性高炎症反应,促炎细胞因子含量显著增加。材料和方法。该研究是在2021年至2022年萨马拉地区儿童传染病医院的基础上进行的。研究了40例COVID-19中度(n = 20,组I)和重度(n = 20,组II)患者,对照组为其他病因的病毒性肺炎患者(n = 35,组III)。感染因子SARS-CoV-2诱导高水平的细胞因子IL-6 (p < 0.005)和IL-8 (p < 0.05), tnf - α略有升高(p < 0.05)。IL-8与病程有显著相关性(p < 0.01)。我们假设这种白细胞介素的价值将在covid后时期增加。结论。COVID-19患者IL-6和IL-8水平的变化以及临床特征是预测疾病严重程度和持续时间的重要生物标志物。版权所有©儿童感染。版权所有
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引用次数: 0
New coronavirus infection in pediatric practice: clinical and epidemiological features of COVID-19 in the city of Smolensk 儿科实践中的新型冠状病毒感染:斯摩棱斯克市COVID-19的临床和流行病学特征
Pub Date : 2023-03-31 DOI: 10.22627/2072-8107-2023-22-1-5-10
V. Sokolovskaya, A. A. Litvinova, D. A. Balukhto, I. N. Kuzmina, A. V. Krikova, R. S. Kozlov
The aim of the study was to study the clinical and epidemiological features of the new COVID-19 coronavirus infection in children hospitalized in the infectious department. Material and methods. 249 case histories of patients from 0 to 18 years of age who are on inpatient treatment at <> in Smolensk for the period from April 2020 to July 2022 were studied by the continuous sampling method. Verification of a new coronavirus infection was carried out by examining smears from the nasopharynx and oropharynx for the presence of SARS-CoV-2 by real-time PCR. Results. The prevalence of patients from 1 to 3 (19.3%, 49.1%) and from 6-15 (15.8%, 50.5%) years was revealed both in 2020 and in 2021 and the first half of 2022. No significant differences in gender were found. The largest number of cases in 2020 was registered in April (16%) and November (14%), in 2021 - in December (18%) and November (16%). The prevailing severity in both 2020 and 2021, 2022 was the average severity (63%, 72%, 93%, respectively). The main syndromes of COVID-19 have been identified: intoxication syndrome, respiratory catarrhal syndrome, bronchopulmonary, intestinal. Bilateral pneumonia was most often detected (47% in 2020, 44% in 2021, 62% in 2022), right-sided pneumonia (33% in 2020, 30% in 2021, 31% in 2022), and left-sided pneumonia (20%, 26% and 7%, respectively). The main co-morbid pathologies are noted, and cases of somatic diseases first registered against the background of COVID-19 are described.Copyright © Children Infections.All rights reserved
本研究旨在研究感染科住院儿童新型冠状病毒感染的临床和流行病学特征。材料和方法。采用连续抽样方法对2020年4月至2022年7月在斯摩棱斯克住院治疗的249例0 ~ 18岁患者的病历进行了研究。通过实时PCR检测鼻咽和口咽涂片是否存在SARS-CoV-2,验证了新的冠状病毒感染。结果。2020年、2021年和2022年上半年分别显示1 ~ 3岁(19.3%,49.1%)和6 ~ 15岁(15.8%,50.5%)患者的患病率。性别差异不显著。2020年登记病例数最多的是4月(16%)和11月(14%),2021年是12月(18%)和11月(16%)。2020年、2021年和2022年的普遍严重程度为平均严重程度(分别为63%、72%和93%)。COVID-19的主要综合征已确定:中毒综合征、呼吸性卡他综合征、支气管肺、肠道。最常发现的是双侧肺炎(2020年为47%,2021年为44%,2022年为62%),右侧肺炎(2020年为33%,2021年为30%,2022年为31%)和左侧肺炎(分别为20%,26%和7%)。介绍了主要的共病病理,并介绍了在COVID-19背景下首次登记的躯体疾病病例。版权所有©儿童感染。版权所有
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引用次数: 0
Possibilities of prediction of сampylobacteriosis adverse outcomes in children 预测儿童<s:1>弯曲杆菌病不良结局的可能性
Pub Date : 2023-03-31 DOI: 10.22627/2072-8107-2023-22-1-14-18
K. Ermolenko
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引用次数: 0
To the 70th anniversary of the Department of Infectious Diseases in Children 庆祝儿童传染病科成立70周年
Pub Date : 2022-11-25 DOI: 10.22627/2072-8107-2022-21-4-67-68
N. Skripchenko, A. N. Uskov, Y. Lobzin
.
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引用次数: 0
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CHILDREN INFECTIONS
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