Pub Date : 2022-03-21DOI: 10.22627/2072-8107-2022-21-1-45-48
D. Bolatova, M. K. Kayrgel'dinova, M. Y. Kazhybay, A. S. Myrzakulova, S. A. Turlybekova, M. A. Sin, D. Y. Zhupenova, P. A. Omirzakova
The aim of the study was to study the features of the course of a new coronavirus infection COVID-19 in hospitalized children. Materials and methods. Clinical manifestations of COVID-19 were studied in 859 children aged 3 months to 16 years old, hospitalized in the children's hospital of Karaganda, Kazakhstan, in the first 6 months of 2021. In all patients, the diagnosis of COVID-19 was confirmed by the detection of SARS-CoV-2 RNA by PCR in nasopharyngeal swabs. Results. In 60% of cases, children aged 7 years and older were ill. More than half of the children (67.6%) had a mild form of the new coronavirus infection COVID-19, and only a third of the patients had a moderate form (31.2%) and 1.2% had a severe form. One child had a multi-inflammatory syndrome (Kawasaki-like). Half of the children had subfebrile or febrile fever (51.1%) and cough (51.2%), as well as signs of intoxication (35.9%), diarrhea (2.4%). In a third of children, the disease proceeded with damage to the lower respiratory tract, with bronchitis and pneumonia (7.8 and 20.3% of cases, respectively). In the general blood test, leukopenia (33.6%), lymphocytosis (45%) were noted. Conclusion. In the first half of 2021, in hospitalized children in Karaganda, Kazakhstan, the new coronavirus infection COVID-19 proceeded favorably in the vast majority of cases.
{"title":"Clinical characteristics of a new coronavirus infection (COVID-19) in children hospitalized in a hospital in Karaganda","authors":"D. Bolatova, M. K. Kayrgel'dinova, M. Y. Kazhybay, A. S. Myrzakulova, S. A. Turlybekova, M. A. Sin, D. Y. Zhupenova, P. A. Omirzakova","doi":"10.22627/2072-8107-2022-21-1-45-48","DOIUrl":"https://doi.org/10.22627/2072-8107-2022-21-1-45-48","url":null,"abstract":"The aim of the study was to study the features of the course of a new coronavirus infection COVID-19 in hospitalized children. Materials and methods. Clinical manifestations of COVID-19 were studied in 859 children aged 3 months to 16 years old, hospitalized in the children's hospital of Karaganda, Kazakhstan, in the first 6 months of 2021. In all patients, the diagnosis of COVID-19 was confirmed by the detection of SARS-CoV-2 RNA by PCR in nasopharyngeal swabs. Results. In 60% of cases, children aged 7 years and older were ill. More than half of the children (67.6%) had a mild form of the new coronavirus infection COVID-19, and only a third of the patients had a moderate form (31.2%) and 1.2% had a severe form. One child had a multi-inflammatory syndrome (Kawasaki-like). Half of the children had subfebrile or febrile fever (51.1%) and cough (51.2%), as well as signs of intoxication (35.9%), diarrhea (2.4%). In a third of children, the disease proceeded with damage to the lower respiratory tract, with bronchitis and pneumonia (7.8 and 20.3% of cases, respectively). In the general blood test, leukopenia (33.6%), lymphocytosis (45%) were noted. Conclusion. In the first half of 2021, in hospitalized children in Karaganda, Kazakhstan, the new coronavirus infection COVID-19 proceeded favorably in the vast majority of cases.","PeriodicalId":9855,"journal":{"name":"CHILDREN INFECTIONS","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79866344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-21DOI: 10.22627/2072-8107-2022-21-1-62-65
V. Greshnyakova, L. G. Goriacheva, A. O. Nikiforova
В большинстве случаев ВЭБ-мононуклеоз у госпитализированных детей протекает в типичной форме, с характерной клинической картиной. Случаи гепатита, как ведущего синдрома при ВЭБ-инфекции, чрезвычайно редки. В статье представлен клинический случай нетипичного начала инфекционного мононуклеоза ВЭБ этиологии, стартовавшего с синдрома поражения печени. Данный клинический опыт дает возможность рекомендовать проведение диагностики на герпесвирусные инфекции в случаях неспецифического поражения печени. Ключевые слова: инфекционный мононуклеоз, неспецифический гепатит, поражение печени при герпетических инфекциях, ВЭБ-инфекция
{"title":"Infectious mononucleosis: atypical manifestation","authors":"V. Greshnyakova, L. G. Goriacheva, A. O. Nikiforova","doi":"10.22627/2072-8107-2022-21-1-62-65","DOIUrl":"https://doi.org/10.22627/2072-8107-2022-21-1-62-65","url":null,"abstract":"В большинстве случаев ВЭБ-мононуклеоз у госпитализированных детей протекает в типичной форме, с характерной клинической картиной. Случаи гепатита, как ведущего синдрома при ВЭБ-инфекции, чрезвычайно редки. В статье представлен клинический случай нетипичного начала инфекционного мононуклеоза ВЭБ этиологии, стартовавшего с синдрома поражения печени. Данный клинический опыт дает возможность рекомендовать проведение диагностики на герпесвирусные инфекции в случаях неспецифического поражения печени. Ключевые слова: инфекционный мононуклеоз, неспецифический гепатит, поражение печени при герпетических инфекциях, ВЭБ-инфекция","PeriodicalId":9855,"journal":{"name":"CHILDREN INFECTIONS","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77538201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-21DOI: 10.22627/2072-8107-2022-21-1-5-15
O. Shamsheva
{"title":"Evolution of the national vaccination calendar. Results and prospects","authors":"O. Shamsheva","doi":"10.22627/2072-8107-2022-21-1-5-15","DOIUrl":"https://doi.org/10.22627/2072-8107-2022-21-1-5-15","url":null,"abstract":"","PeriodicalId":9855,"journal":{"name":"CHILDREN INFECTIONS","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73721131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-21DOI: 10.22627/2072-8107-2022-21-1-16-22
L. Mazankova, E. Samitova, I. Osmanov, N. A. Drachevа, E. P. Kaurova
This article presents an observation of 12 patients with combined forms of COVID-19 and acute respiratory viral infections hospitalized at the Z.A. Bashlyaeva State Clinical Hospital, the purpose of which was to identify the features of the course of COVID-19 coronavirus infection in combination with acute respiratory viral infections of various etiologies in children. According to the data obtained, the incidence of COVID-19 and ARVI co-infections was 4.2%. There is a tendency to an increase in the number of patients with lower respiratory tract lesions, a tendency to a prolonged course of COVID-19 with concomitant ARVI, as well as an increase in the duration of hospitalization of patients.
{"title":"Combined forms of COVID-19 with acute respiratory viral infections in children","authors":"L. Mazankova, E. Samitova, I. Osmanov, N. A. Drachevа, E. P. Kaurova","doi":"10.22627/2072-8107-2022-21-1-16-22","DOIUrl":"https://doi.org/10.22627/2072-8107-2022-21-1-16-22","url":null,"abstract":"This article presents an observation of 12 patients with combined forms of COVID-19 and acute respiratory viral infections hospitalized at the Z.A. Bashlyaeva State Clinical Hospital, the purpose of which was to identify the features of the course of COVID-19 coronavirus infection in combination with acute respiratory viral infections of various etiologies in children. According to the data obtained, the incidence of COVID-19 and ARVI co-infections was 4.2%. There is a tendency to an increase in the number of patients with lower respiratory tract lesions, a tendency to a prolonged course of COVID-19 with concomitant ARVI, as well as an increase in the duration of hospitalization of patients.","PeriodicalId":9855,"journal":{"name":"CHILDREN INFECTIONS","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89580140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-21DOI: 10.22627/2072-8107-2022-21-1-41-44
O. A. Saburova, D. Sobchak, K. Otmakhova
{"title":"Study of T-cell immunity, interferogenesis, inflammatory mediators in children with Varicella zoster virus infection","authors":"O. A. Saburova, D. Sobchak, K. Otmakhova","doi":"10.22627/2072-8107-2022-21-1-41-44","DOIUrl":"https://doi.org/10.22627/2072-8107-2022-21-1-41-44","url":null,"abstract":"","PeriodicalId":9855,"journal":{"name":"CHILDREN INFECTIONS","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74891526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-21DOI: 10.22627/2072-8107-2022-21-1-23-28
K. V. Dashichev, N. V. Olendar, O. V. Kulibina, E. P. Sitnikova, T. Vinogradova
Проводилось изучение неврологического статуса и вариабельности сердечного ритма (ВСР) 40 недоношенных новорожденных, у которых неврологический статус характеризовался симптомами общего угнетения (СОУ) центральной нервной системы (ЦНС). На основе спектральных показателей вариабельности сердечного ритма среди последних была выделена группа детей с низкой активностью субкортикальных стимулирующих систем, генерирующих катехоламины (СССк), у которых СОУ ЦНС имел определенные отличия клинической картины. Предполагается, что в этой группе недоношенных новорожденных детей данный синдром был обусловлен недостаточной постнатальной активностью СССк вследствие её антенатального ингибирования экзогенными адреномиметиками. Ключевые слова: недоношенные дети, центральная нервная система
{"title":"About pathogenesis of depressive state of central nervous system in premature infants","authors":"K. V. Dashichev, N. V. Olendar, O. V. Kulibina, E. P. Sitnikova, T. Vinogradova","doi":"10.22627/2072-8107-2022-21-1-23-28","DOIUrl":"https://doi.org/10.22627/2072-8107-2022-21-1-23-28","url":null,"abstract":"Проводилось изучение неврологического статуса и вариабельности сердечного ритма (ВСР) 40 недоношенных новорожденных, у которых неврологический статус характеризовался симптомами общего угнетения (СОУ) центральной нервной системы (ЦНС). На основе спектральных показателей вариабельности сердечного ритма среди последних была выделена группа детей с низкой активностью субкортикальных стимулирующих систем, генерирующих катехоламины (СССк), у которых СОУ ЦНС имел определенные отличия клинической картины. Предполагается, что в этой группе недоношенных новорожденных детей данный синдром был обусловлен недостаточной постнатальной активностью СССк вследствие её антенатального ингибирования экзогенными адреномиметиками. Ключевые слова: недоношенные дети, центральная нервная система","PeriodicalId":9855,"journal":{"name":"CHILDREN INFECTIONS","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86360971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-21DOI: 10.22627/2072-8107-2022-21-1-56-61
S. B. Chuelov, A. L. Rossina
{"title":"Imaginal cestodiasis","authors":"S. B. Chuelov, A. L. Rossina","doi":"10.22627/2072-8107-2022-21-1-56-61","DOIUrl":"https://doi.org/10.22627/2072-8107-2022-21-1-56-61","url":null,"abstract":"","PeriodicalId":9855,"journal":{"name":"CHILDREN INFECTIONS","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81082532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-21DOI: 10.22627/2072-8107-2021-21-1-33-40
G. A. Kharchenko, O. G. Kimirilova, A. A. Kimirilov
The average number of annually registered cases of botulism in the Russian Federation is 300. At the same time, there is an increase in the number of deaths to 26 per year.Materials and methods. The article presents the results of a clinical and epidemiological analysis of 47 cases of botulism in adults treated at the State Medical Institution «Regional Infectious Clinical Hospital named after A.M. Nichoga» in Astrakhan in the period from 2009 to 2019. The diagnosis of botulism was confirmed by a positive reaction of biological neutralization of the toxin in white mice.Results. It is established that the epidemic process of botulism in the Astrakhan region is characterized mainly by sporadic morbidity in adults of working age and the absence of cases of the disease in children. All patients had food botulism, which occurred typically in the form of moderate and severe forms of the disease, with a mortality rate of 4.2%. There is an increase in the share of fish and fish products, non-industrial preparation, as sources of infection. Laboratory confirmation of botulism occurred in 60% of patients.
{"title":"Botulism in the Astrakhan region: a retrospective study","authors":"G. A. Kharchenko, O. G. Kimirilova, A. A. Kimirilov","doi":"10.22627/2072-8107-2021-21-1-33-40","DOIUrl":"https://doi.org/10.22627/2072-8107-2021-21-1-33-40","url":null,"abstract":"The average number of annually registered cases of botulism in the Russian Federation is 300. At the same time, there is an increase in the number of deaths to 26 per year.Materials and methods. The article presents the results of a clinical and epidemiological analysis of 47 cases of botulism in adults treated at the State Medical Institution «Regional Infectious Clinical Hospital named after A.M. Nichoga» in Astrakhan in the period from 2009 to 2019. The diagnosis of botulism was confirmed by a positive reaction of biological neutralization of the toxin in white mice.Results. It is established that the epidemic process of botulism in the Astrakhan region is characterized mainly by sporadic morbidity in adults of working age and the absence of cases of the disease in children. All patients had food botulism, which occurred typically in the form of moderate and severe forms of the disease, with a mortality rate of 4.2%. There is an increase in the share of fish and fish products, non-industrial preparation, as sources of infection. Laboratory confirmation of botulism occurred in 60% of patients.","PeriodicalId":9855,"journal":{"name":"CHILDREN INFECTIONS","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86709525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-13DOI: 10.22627/2072-8107-2021-20-1s-2-129
Article Editorial
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{"title":"Материалы XX юбилейного Конгресса детских инфекционистов России. «Актуальные вопросы инфекционной патологии и вакцинопрофилактики»","authors":"Article Editorial","doi":"10.22627/2072-8107-2021-20-1s-2-129","DOIUrl":"https://doi.org/10.22627/2072-8107-2021-20-1s-2-129","url":null,"abstract":"<jats:p>.</jats:p>","PeriodicalId":9855,"journal":{"name":"CHILDREN INFECTIONS","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84053060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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