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Oral epithelial dysplasia: Do we have a management solution? A systematic review 口腔上皮发育不良:我们有管理解决方案吗?系统回顾
Pub Date : 2025-06-01 Epub Date: 2025-03-17 DOI: 10.1016/j.adoms.2025.100533
Navini Mannapperuma , Chiew Ying Chieng , Velupillai Ilankovan
Currently there is no definite approved guidelines over the treatment and follow-up required for patients with oral epithelial dysplasia (OED). There are ample controversies based on predicting the malignant transformation potential and deciding the management options solely based on the degree of epithelial dysplasia. The objective of this review was to identify an evidence-based management pathway for OED. The systematic review was conducted using PubMed, EMBASE using PRISMA guidelines. Following applications of inclusion and exclusion criteria, only 12 studies were included in the review. Overall, there were a wide variation in the reported recurrence rate (2.5 %–51.4 %) and the malignant transformation rate (MTR) (2.6–27 %). The degree of dysplasia was not significant in malignant transformation. The mainstay of treatment includes observation, laser ablation and excision with no concrete evidence of resolution. Therefore, there is an urgent need for a multidisciplinary conference to create a consensus for treatment pathway for OED.
目前,对于口腔上皮发育不良(OED)患者的治疗和随访,还没有明确的批准指南。仅根据上皮发育不良的程度来预测肿瘤的恶性转化潜力和决定治疗方案存在很大的争议。本综述的目的是为OED确定循证管理途径。系统评价使用PubMed、EMBASE和PRISMA指南进行。在应用纳入和排除标准后,只有12项研究被纳入本综述。总体而言,报告的复发率(2.5% - 51.4%)和恶性转化率(MTR)(2.6 - 27%)差异很大。恶性转化的不典型增生程度无统计学意义。主要的治疗方法包括观察、激光消融和切除,但没有具体的治疗证据。因此,迫切需要召开多学科会议,就OED的治疗途径达成共识。
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引用次数: 0
Inclusion Body Myositis presenting with macroglossia: A diagnostic challenge 包涵体肌炎表现为大舌缺损:一个诊断挑战
Pub Date : 2025-06-01 Epub Date: 2025-03-01 DOI: 10.1016/j.adoms.2025.100531
Aaron Patel, Suresh Shetty
Patients with Inclusion Body Myositis (IBM) may present with symptoms such as dysarthria and dysphagia, often before a formal diagnosis. Increased awareness and understanding of IBM among clinicians can help identify early signs, leading to timely referrals to specialist teams. Raising awareness of IBMs oral manifestations will empower clinicians to play a key role in the multidisciplinary management of this progressive disease.
包涵体肌炎(IBM)患者通常在正式诊断前表现为构音障碍和吞咽困难等症状。提高临床医生对IBM的认识和理解有助于识别早期症状,从而及时转介到专家团队。提高对ibm口腔表现的认识将使临床医生在这种进行性疾病的多学科管理中发挥关键作用。
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引用次数: 0
Social deprivation and severe cervicofacial abscess: A retrospective review of patients presenting to a tertiary oral and maxillofacial surgery unit 社会剥夺和严重颈面脓肿:一个回顾性的回顾病人提出三级口腔颌面外科单位
Pub Date : 2025-06-01 Epub Date: 2025-04-18 DOI: 10.1016/j.adoms.2025.100546
Clarissa Hjalmarsson , Mark Cairns , William Rohde , Domniki Chatzopoulou , Simon Holmes

Background

Severe cervicofacial abscesses require emergency incision and drainage under general anaesthetic to avoid life-threatening sequelae. There is a well-described association between dental disease and socioeconomic status (SES), and most cervicofacial abscesses are odontogenic.

Methods

We retrospectively reviewed the relationship between severe cervicofacial infection and SES in patients presenting to a tertiary Oral and Maxillofacial Surgery (OMFS) unit.

Results

There were 96 patients with severe cervicofacial abscess in 2019–20, increasing by 11.5 %–107 patients in 2021–22 (t-test = −0.665, p = 0.513). Patients were disproportionately from the most deprived areas, with a majority of patients living in the three most deprived deciles in both datasets (71.9 % and 64.7 % respectively). There was no statistical difference in deprivation indices between the two time periods (X2 = 7.44, p = 0.591). While the cohorts had high indices of deprivation, these were not significantly different to the areas served by the hospital (X2 = 11.42, p = 0.248).

Conclusions

This dataset demonstrates a high incidence of severe cervicofacial abscess in a deprived population. This relationship is likely to reflect a number of factors including access to primary dental care, lifestyle factors including smoking, and background medical comorbidities. Further iterations of data collection and multi-centre collaboration will improve our understanding of the relationship between social deprivation and severe cervicofacial abscess.
背景:严重的颈面脓肿需要在全身麻醉下紧急切开引流,以避免危及生命的后遗症。有一个很好的描述牙病和社会经济地位(SES)之间的联系,大多数颈面脓肿是牙源性的。方法回顾性分析在三级口腔颌面外科(OMFS)就诊的患者严重颈面感染与SES的关系。结果2019-20年度发生严重颈面脓肿96例,比2021-22年度增加11.5% (t检验= - 0.665,p = 0.513)。患者不成比例地来自最贫困地区,在两个数据集中,大多数患者生活在最贫困的三个十分位数(分别为71.9%和64.7%)。两个时间段的剥夺指数比较,差异无统计学意义(X2 = 7.44, p = 0.591)。虽然这些队列的剥夺指数很高,但这些指数与医院服务的地区没有显著差异(X2 = 11.42, p = 0.248)。结论:该数据集表明,在贫困人群中,严重颈面脓肿的发生率很高。这种关系可能反映了许多因素,包括获得初级牙科保健、生活方式因素(包括吸烟)和背景医疗合并症。数据收集和多中心合作的进一步迭代将提高我们对社会剥夺与严重颈面脓肿之间关系的理解。
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引用次数: 0
Managing airway emergencies on the Ward: Lessons learned from Rapid Rhino pack herniation 管理病房的气道紧急情况:从快速犀牛群疝中吸取的教训
Pub Date : 2025-06-01 Epub Date: 2025-04-18 DOI: 10.1016/j.adoms.2025.100547
Alicia Wong, James Davies, Ra'ed Al-Ashqar
Managing epistaxis is a skill encountered by both maxillofacial and ENT trainees. This case report details an incident where a patient's airway was compromised due to the herniation of a Rapid Rhino pack. The airway distress occurred after nasal packing, necessitating emergency intervention. The ENT team assessed the patient, discovering a Rapid Rhino pack obstructing the airway. Immediate A-E assessment was completed and the pack was removed nasally. The cause of the herniation was considered to be anatomical, a defective pack, overinflation, or a combination of these factors.
鼻出血的处理是颌面部和耳鼻喉科学员都遇到的一项技能。本病例报告详细说明了一个事件,其中病人的气道受损,由于一个快速犀牛包疝。鼻填塞后发生气道窘迫,需要紧急干预。耳鼻喉科小组对患者进行了评估,发现一个快速犀牛包阻塞了气道。立即完成A-E评估,并通过鼻腔取出包。疝的原因被认为是解剖学上的,有缺陷的包,过度膨胀,或这些因素的组合。
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引用次数: 0
Impact of surgical consultation and counseling on patients perspectives regarding nasal shape and expectations from rhinoplasty 外科会诊和咨询对患者对鼻形状的看法和对鼻整形的期望的影响
Pub Date : 2025-06-01 Epub Date: 2025-04-04 DOI: 10.1016/j.adoms.2025.100540
Georges Ziade , Georges Abikanaan , Dayane Daou , Desiree Karam , Elias Keyrouz , Rami Saade

Background and objectives

Surgical rhinoplasty is a challenging aesthetic procedure, where patient satisfaction is the primary measure of success. This study assessed patients' perceptions of their nose shapes before and after a surgical consultation, using the Face-Q questionnaire.

Materials and methods

Patients attending preoperative consultations for primary rhinoplasty completed the Face-Q questionnaire; additional questions included those on nasal symmetry and skin regularity. Subsequently, the same questions were answered after standardized clinical assessment-based photos and measurements. The two sets of answers and demographic data analysis were compared. The study group was stratified by age into younger than or equal to, and older than 21 years, and compared using previously mentioned statistical methods.

Results

Forty patients, predominantly women (65 %), with a mean age of 26.5 years, were included. The Face-Q scores significantly changed after the objective assessment (mean change 3.30, p < 0.001). Stratification by age showed statistically significant differences in all questions for participants above 21, while those below 21 exhibited significant changes in all questions except those on columellar symmetry.

Conclusion

A preoperative review of a rhinoplasty patient's own nasal features through photographs influenced their perception of their nose, highlighting the importance of preoperative counseling in managing patient expectations effectively.
背景与目的鼻整形手术是一项具有挑战性的美容手术,患者满意度是成功的主要衡量标准。这项研究使用Face-Q问卷评估了患者在手术会诊前后对自己鼻子形状的感知。材料与方法参加初次鼻整形术前会诊的患者填写Face-Q问卷;其他问题还包括关于鼻子对称性和皮肤规律性的问题。随后,在标准化的基于临床评估的照片和测量后,回答同样的问题。比较两组答案和人口统计数据分析。研究组按年龄分为小于或等于21岁和大于21岁,并使用前面提到的统计方法进行比较。结果纳入40例患者,以女性为主(65%),平均年龄26.5岁。客观评估后,Face-Q得分发生显著变化(平均变化3.30,p <;0.001)。年龄分层显示,21岁以上的参与者在所有问题上的差异具有统计学意义,而21岁以下的参与者在除小柱对称外的所有问题上都有显著变化。结论术前通过照片对隆鼻患者自身的鼻部特征进行回顾会影响他们对自己鼻子的感知,这突出了术前咨询对有效管理患者期望的重要性。
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引用次数: 0
Double-cinch suturing during Le Fort Ⅰ osteotomy Le FortⅠ截骨术中双钳缝合
Pub Date : 2025-06-01 Epub Date: 2025-04-30 DOI: 10.1016/j.adoms.2025.100550
Takuma Watanabe, Kazumasa Nakao, Shigeki Yamanaka, Makoto Hirota
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引用次数: 0
Evaluation of lateral and axial forces in atrophic maxilla with angled pterygoid implant using three dimensional finite element analysis 用三维有限元分析评估倾斜翼状种植体萎缩上颌的侧向力和轴向力
Pub Date : 2025-06-01 Epub Date: 2025-04-25 DOI: 10.1016/j.adoms.2025.100545
Thair Mahroq , Ahmet Arslan , İbrahim Mutlu , Zakaria Al Joulaji
The purpose of this research is to identify the angle of pterygoid implant that have minimum equivalent stress and minimum equivalent strain using the finite element analysis (FEA) technique, based on the Frankfort Horizontal Plane. A three-dimensional maxilla model was reconstructed from a CT scan of a toothless patient. This model includes the cancellous and cortical bone. The facial region of a 58-year-old male patient with an atrophic maxilla and an angled pterygoid implant was imaged with CT in DICOM format. The raw DICOM data had a 0.3-mm section thickness. The MIMICS program created a three-dimensional model of the sections bone tissue. A dental implant with a diameter of 3.5 mm, a length of 16 mm, a conical shape, and a private thread design was placed in the pterygoid bone using SOLIDWORKS. This study investigated at how to place a pterygoid dental implant using both monocortical (at the end of the crest and cancellous bone) and bicortical (between the crest and basal bone) methods at 45, 55, 65, 75, and 85° relative to the Frankfort Horizontal Plane. Ten models were used for this study. CAD models were sent to ANSYS for loading. Boundaries of maxilla before force application are fixed from the zygomatic region. Human mastication was simulated using three load situations with the following characteristics, 150-N axial loading and 50-N lateral loading separately and 50-N lateral loading and 150-N axial loading simultaneously. Based on our studies and according to the Frankfort Horizontal Plane, placing the pterygoid implant at an 85° angle is the best in terms of bone stress. In terms of bone strain, it was found that placing the implant at 75 and 85° angles monocortically and bicortically respectively has the best outcome. This research concluded that an angle of 85° exhibits the minimum stress and strain effects on the surrounding bone tissue and the implant's structural integrity.
本研究的目的是利用基于法兰克福水平平面的有限元分析(FEA)技术,确定翼状假体具有最小等效应力和最小等效应变的角度。通过对无牙患者的CT扫描,重建了一个三维上颌骨模型。该模型包括松质骨和皮质骨。本文采用DICOM格式CT对58岁男性上颌萎缩、翼状骨倾斜植入患者的面部进行了影像学检查。原始DICOM数据的切片厚度为0.3 mm。MIMICS程序创建了骨组织切片的三维模型。使用SOLIDWORKS将直径为3.5 mm、长度为16 mm、圆锥形、专用螺纹设计的种植体放置在翼状骨内。本研究探讨了如何使用单皮质(在嵴和松质骨的末端)和双皮质(在嵴和基底骨之间)方法在相对法兰克福水平面45°、55°、65°、75°和85°放置翼状牙种植体。本研究共使用了10个模型。将CAD模型送入ANSYS进行加载。上颌用力前的边界从颧区固定。采用分别为150-N轴向加载和50-N侧向加载以及50-N侧向加载和150-N轴向加载的三种载荷情况模拟人类咀嚼行为。根据我们的研究,并根据法兰克福水平面,放置翼状骨种植体在85°角是最好的骨应力。在骨应变方面,我们发现单皮质和双皮质分别放置种植体75°和85°的角度效果最好。本研究得出的结论是,85°角对周围骨组织和种植体结构完整性的应力和应变影响最小。
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引用次数: 0
Time patterns of recurrence and correlating histomorphology to delay of recurrence of benign jaw tumours: A 10-year appreciation 复发的时间模式和相关的组织形态学延迟良性颌骨肿瘤复发:10年的升值
Pub Date : 2025-06-01 Epub Date: 2025-02-10 DOI: 10.1016/j.adoms.2025.100526
Zilefac Brian Ngokwe , Ntep Ntep David Bienvenue , Nokam Kamdem Stephane , Kouamou Tchiekou Audrey , Atanwo Nita Lise Dongmo , Bengondo Messanga Charles , Sando Zacharie

Introduction

Patients presenting a recurrent benign jaw tumour have many complications, among which increased morbidities and mortalities, malignant degeneration of these benign tumours, aesthetic as well as functional sequalae and high medical bills. Hence, we sought out through a retrospective study to evaluate the patterns of these recurrences to help us appreciate and help predict recurrences to improve the overall wellbeing of these patients.

Methods

We carried out a retrospective study during the period of January 2010 to April 2020 at 3 medical centers in Yaoundé. We obtained the necessary ethical approval and administrative authorizations. All study participants having a histological diagnosis of a benign jaw tumour and presenting with at least one tumour recurrence were included in our study. The histological diagnoses were reconfirmed and we excluded all participants with pathology slides that could not be retrieved or those that could not undergo histological analysis.

Results

We retrieved 19 cases of benign tumour recurrences in this 10-year period and finally retained 14 cases of benign tumour recurrences in our study with a total of 7 different histological diagnoses. Also, all our cases of recurrences were found between the second and fifth decade with ameloblastoma having the most cases of recurrences in our study. The mean duration of recurrence for participants with one recurrence only was 6.31years ± 6.08, while those with ≥2 recurrences was 3.50years ± 2.95. Looking at the histomorphology, the mean duration of first recurrence of ameloblastoma in our study was 5 years, relatively shorter than the combined mean duration of first recurrence for all tumours recurrences which was 5.55years ± 5.49.

Conclusion

The mean duration of first, second and third recurrences were 5.55years ± 5.49, 2.17years ± 1.47 and 2.80years ± 2.88 respectively. These durations and patterns could help as surgical post operative follow up period after jaw tumour recurrences.
复发性良性颌骨肿瘤患者有许多并发症,其中包括发病率和死亡率增加,良性肿瘤恶性变性,美观和功能后遗症以及高昂的医疗费用。因此,我们通过回顾性研究来评估这些复发的模式,以帮助我们了解和预测复发,从而改善这些患者的整体健康状况。方法对2010年1月至2020年4月在云南省3个医疗中心进行回顾性研究。我们获得了必要的伦理批准和行政授权。所有组织学诊断为良性颌骨肿瘤且至少有一次肿瘤复发的研究参与者都被纳入我们的研究。再次确认组织学诊断,我们排除了所有无法检索病理切片或无法进行组织学分析的参与者。结果我们在这10年的时间里检索了19例良性肿瘤复发,最终保留了14例良性肿瘤复发,共有7种不同的组织学诊断。此外,我们所有的复发病例都是在第二到第五十年之间发现的,在我们的研究中,成釉细胞瘤的复发病例最多。复发1次的平均复发时间为6.31年±6.08年,复发2次以上的平均复发时间为3.50年±2.95年。从组织学上看,我们研究中成釉细胞瘤的平均首次复发时间为5年,相对于所有肿瘤复发的平均首次复发时间(5.55年±5.49年)的总和要短。结论首次、第二次、第三次复发的平均时间分别为5.55年±5.49年、2.17年±1.47年和2.80年±2.88年。这些持续时间和模式可以作为颌骨肿瘤复发后的外科术后随访期。
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引用次数: 0
Condylar volume changes following minimally invasive orthognathic surgery: A case report 微创正颌手术后髁突体积变化1例报告
Pub Date : 2025-03-01 Epub Date: 2024-12-16 DOI: 10.1016/j.adoms.2024.100511
Nelson J. León , Stefanía Requejo , Ronar Gudiño , Henry García , Steven Rodríguez
Minimally invasive orthognathic surgery (MIOS) represents a significant paradigm shift in oral and maxillofacial surgery. The impact of MIOS on the temporomandibular joint (TMJ) remains a topic of debate. This case report aims to evaluate changes in mandibular condylar volume in the TMJ following MIOS and establish a foundation for further research in this area.
微创正颌手术(MIOS)代表了口腔颌面外科的重大范式转变。MIOS对颞下颌关节(TMJ)的影响仍然是一个有争议的话题。本病例报告旨在评估MIOS后TMJ下颌髁突体积的变化,为该领域的进一步研究奠定基础。
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引用次数: 0
Aesthetic and functional sequelae of patients operated upon for benign jaw tumours at a tertiary hospital in Cameroon 喀麦隆一家三级医院手术治疗良性颌肿瘤患者的美学和功能后遗症
Pub Date : 2025-03-01 Epub Date: 2024-11-30 DOI: 10.1016/j.adoms.2024.100507
Atanwo Nita Lise Dongmo, Edouma Bohimbo Jacques, Kwedi Karl, Mboya Marius, Nkollo Francis, Bengondo Messanga Charles

Introduction and general objective

Benign tumours develop locally and remain confined to the tissue in which they originate. They grow slowly. However, they can grow to significant size and weight. They rarely reoccur after surgical removal. Their evolution is generally favourable. In some cases, however, they can cause serious or even morbid complications, due to their location or metabolic disorders.There are two types of management for these tumours: conservative surgery, which consists of removing the tumour with a margin of healthy surrounding tissue, while preserving the role and appearance of the organ in question; and radical surgery, which is the removal of a diseased organ and all surrounding tissues likely to be affected by the disease. These treatments can lead to loss of substance, resulting in both functional and aesthetic sequelae.
The general objective of our study was to: Determine the aesthetic and functional sequelae of patients operated on for benign jaw tumours at the Yaoundé Central Hospital.

Methodology

We conducted a descriptive cross-sectional from January 1, 2013 to January 1, 2023 with prospective data collection in the ENT and Cervico Maxillofacial Surgery Department of the Yaoundé Central Hospital. Patient recruitment was consecutive and non-exhaustive. Epidemiological, clinical and anatomopathological data were collected, as well as the various aesthetic and functional sequelae.
This study concerned all patients operated on for benign tumours presenting anatomopathological evidence and having given their informed consent at the Yaoundé Central Hospital. Patients who were lost to follow-up, deceased or who had not given consent were excluded.

Results

39 patients were recruited; 16 men and 23 women, giving a sex ratio of 0.69. The mean age was 36.18 ± 15.38 years, a minimum of 14 years and a maximum of 71 years. Ameloblastoma was the most common tumour (38.5 %). The most common method of treatment was radical surgery, and the most common material used for reconstruction was the screw-plate (86.9 %). Sequelae were found in 35 patients (89.74 %), the most common functional sequelae being impaired mastication (92.5 %). Aesthetic sequelae were mainly marked by facial asymmetry (66.7 %).

Conclusion

The fourth decade of female gender was the most represented population among patients operated on for benign tumours of the jaws. Radical surgery was more commonly used in our work. Among the aesthetic sequelae in our study, we noted facial asymmetries, scars and their location were predominantly mandibular. The most common functional sequelae were impaired mastication, nerve damage and impaired speech.
简介和一般目的良性肿瘤在局部发展,并局限于其起源的组织。它们长得很慢。然而,它们可以长到很大的尺寸和重量。手术切除后很少复发。它们的进化通常是有利的。然而,在某些情况下,由于它们的位置或代谢紊乱,它们可能导致严重甚至病态的并发症。这些肿瘤有两种治疗方法:保守手术,即切除肿瘤并保留周围健康组织的边缘,同时保留有关器官的作用和外观;还有根治性手术,就是切除患病器官和所有可能受疾病影响的周围组织。这些治疗可能导致物质的损失,导致功能和美学的后遗症。我们研究的总体目的是:确定在雅温顿中心医院手术的良性颌骨肿瘤患者的美学和功能后遗症。方法2013年1月1日至2023年1月1日在雅温市中心医院耳鼻喉科和颈颌面外科进行描述性横断面前瞻性数据收集。患者招募是连续且非详尽的。收集流行病学、临床和解剖病理学资料,以及各种美学和功能后遗症。本研究涉及所有在雅温顿中心医院接受良性肿瘤手术并提供解剖病理证据并给予知情同意的患者。失去随访、死亡或未给予同意的患者被排除在外。结果共纳入39例患者;16名男性和23名女性,性别比例为0.69。平均年龄36.18±15.38岁,最小14岁,最大71岁。成釉细胞瘤是最常见的肿瘤(38.5%)。最常见的治疗方法是根治性手术,最常用的重建材料是螺钉板(86.9%)。后遗症35例(89.74%),最常见的功能性后遗症为咀嚼功能受损(92.5%)。美学后遗症主要表现为面部不对称(66.7%)。结论女性是颌骨良性肿瘤手术患者中最具代表性的人群。根治性手术在我们的工作中更常用。在我们研究的美学后遗症中,我们注意到面部不对称,疤痕及其位置主要是下颌。最常见的功能性后遗症是咀嚼功能受损、神经损伤和语言功能受损。
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引用次数: 0
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Advances in Oral and Maxillofacial Surgery
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