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Effectiveness Of Non-Pharmacological Treatments In Decreasing Tourette Syndrome Symptoms 非药物治疗对减轻妥瑞症症状的效果
Pub Date : 2024-09-01 DOI: 10.1016/j.dentre.2024.100121
Margareth Rivas, Danila Dokuchayev, Ashely Christman RDH, BS

OBJECTIVES

To determine the effectiveness of non-pharmacological treatments in suppressing Tourette's Syndrome symptoms.

METHODS

The PubMed database was accessed through Augusta University Greenblatt Library. The database was used to search for articles about how occlusal splints suppress Tourette's symptoms. Articles filters included random control trials, peer-reviewed, and clinical trials, that were published within the last five years. Key terms that were utilized were "Tourette's Syndrome/Therapy," "Occlusal Splint," "Deep Brain Stimulation," "Transcranial Magnetic Stimulation,” and "Tics". Articles excluded were meta-analyses, systematic reviews, and literature reviews.

RESULTS

Participants receiving the proper individualized therapeutic height for their occlusal splint demonstrated a consistent decrease in their Tourette symptoms based on the mean clinical global impressionsimprovement scale (CGI-S) rating when compared to participants not receiving a proper individualized therapeutic height for their occlusal splint. An occlusal splint is viable in providing immediate tic symptom improvement. The use of an occlusal splint is effective, non-invasive, tolerable, and grants minimal risk when compared to deep brain stimulation and transcranial magnetic stimulation.

CONCLUSIONS

Compared to other non-pharmacological options such as deep brain stimulation or transcranial magnetic stimulation, the occlusal splint is a nonsurgical procedure that not only requires less time to be completed but offers fewer adverse effects for the patient, with promising results.

IMPLICATIONS

Pharmacological treatment is known as the “Golden Standard” of care when treating Tourette syndrome symptoms. Understanding how nonpharmacological treatments may affect those with Tourette syndrome, offers additional treatment options. The usage of non-pharmacological treatments such as an occlusal splint has the potential to benefit individuals with Tourette syndrome, further advancing the oral-systemic health connection.

方法通过奥古斯塔大学格林布拉特图书馆访问 PubMed 数据库。该数据库用于搜索有关咬合夹板如何抑制妥瑞症症状的文章。文章筛选包括过去五年内发表的随机对照试验、同行评审和临床试验。关键词包括 "妥瑞症/治疗"、"咬合夹板"、"脑深部刺激"、"经颅磁刺激 "和 "抽搐"。结果根据临床总体印象改善量表(CGI-S)的平均评分,为咬合夹板提供适当个性化治疗高度的参与者与未为咬合夹板提供适当个性化治疗高度的参与者相比,其妥瑞症症状持续减轻。咬合夹板可以立即改善抽搐症状。与深部脑刺激和经颅磁刺激相比,使用咬合夹板有效、无创、可耐受且风险最小。结论与脑深部刺激或经颅磁刺激等其他非药物治疗方法相比,咬合夹板是一种非手术治疗方法,不仅所需时间较短,而且对患者的不良影响较小,效果良好。了解非药物治疗对妥瑞症患者的影响,可以为患者提供更多的治疗选择。使用咬合夹板等非药物疗法有可能使妥瑞症患者受益,进一步促进口腔系统健康的联系。
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引用次数: 0
Oral Health Impact on Ventilator-Associated Pneumonia 口腔健康对呼吸机相关肺炎的影响
Pub Date : 2024-09-01 DOI: 10.1016/j.dentre.2024.100122
Bailey Miles, Sarah Beth Tanner, Krystal Herring RDH, MPH

OBJECTIVES

Evaluate the role oral hygiene plays in decreasing the risk of contracting Ventilator-Associated Pneumonia (VAP) for patients on life-support.

METHODS

Five different research studies were used to measure the effectiveness of various mouthwashes ability to prevent VAP. The mouthwashes evaluated were Clove mouthwash, Ozonated Water (OZW), Chlorohexidine Gluconate (CHG), and Povidone Iodine. For each study, the patients were split into a control and experimental group. All patients were treated with the designated mouthwash, using a mouth swab for application. There was a variation of the duration of each study, as well as the time intervals of mouthwash application. The studies were conducted over the course of anywhere from a few hours to several days. There were numerous data collection instruments used throughout each study to measure the incidence of VAP contraction, such as Acute Physiology and Chronic Health Evaluation II (APACHEII), The Beck Oral Assessment Scale (BOAS), and Modified Clinical Pulmonary Infection Score (MCPIS).

RESULTS

• Study One: 40% participants in Chlorohexidine group contracted VAP; double that of the Clove Extract group • Study Two: 9 out of 36 patients in OZW group contracted VAP; 17 out of 37 patients in CHG group contracted VAP • Study Three: Experimental group showed an overall reduction in bacterial growth • Study Four: 0% VAP contraction in experimental group; 10.58% contraction in control group • Study Five: 10 patients in CHG group contracted VAP; 17 patients in placebo group contracted VAP

CONCLUSIONS

Overall, this literature review confirms that mouthwash solutions do have a positive effect in the reduction of VAP in critically ill patients. However, research has not consistently shown one solution to be more triumphant than another, when compared.

IMPLICATIONS

In a hospital setting the findings influence clinical dentistry by showing the importance of providing professional cleanings within 24 hours of mechanical ventilation, providing oral care using an antibacterial mouthwash 3 times a day, and ensuring that patients teeth are brushed twice a day. In a private practice setting the findings show the importance/need of advocating for patients receiving proper oral care while in a critically ill state and spreading awareness on the effect that oral hygiene has on preventing VAP.

目的评估口腔卫生在降低接受生命支持的患者感染呼吸机相关肺炎 (VAP) 的风险方面所起的作用。方法使用五项不同的研究来衡量各种漱口水预防 VAP 的有效性。接受评估的漱口水包括丁香漱口水、臭氧水 (OZW)、葡萄糖酸氯己定 (CHG) 和聚维酮碘。每项研究都将患者分为对照组和实验组。所有患者都使用指定的漱口水进行治疗,并使用口腔棉签涂抹。每项研究的持续时间和使用漱口水的时间间隔各不相同。研究时间从几小时到几天不等。每项研究都使用了大量数据收集工具来测量 VAP 感染率,如急性生理学和慢性健康评估 II (APACHEII)、贝克口腔评估量表 (BOAS) 和改良临床肺部感染评分 (MCPIS)。结果-- 研究一:氯己定组有 40% 的参与者感染了 VAP;是丁香提取物组的两倍-- 研究二:OZW 组的 36 名患者中有 9 名感染了 VAP;CHG 组的 37 名患者中有 17 名感染了 VAP-- 研究三:研究四:实验组的 VAP 感染率为 0%;对照组的感染率为 10.58% - 研究五:CHG 组有 10 名患者感染 VAP;安慰剂组有 17 名患者感染 VAPCONCLUSIONSOverall, this literature review confirms that mouthwash solutions do have a positive effect in the reduction of VAP in critically ill patients.意义在医院环境中,研究结果表明了在机械通气 24 小时内提供专业清洁、每天使用抗菌漱口水进行口腔护理 3 次以及确保患者每天刷牙两次的重要性,从而对临床牙科治疗产生了影响。在私人诊所中,研究结果表明了倡导病人在重病状态下接受适当口腔护理的重要性/必要性,以及宣传口腔卫生对预防 VAP 的影响。
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引用次数: 0
Distortion Of Printed Resin Surgical Guides After Autoclave Sterilization And Chemical Disinfection 高压灭菌和化学消毒后印刷树脂手术导板的变形
Pub Date : 2024-09-01 DOI: 10.1016/j.dentre.2024.100139
Natasha Gandarilla DMD
<div><h3>OBJECTIVES</h3><p>To examine the level of distortion of 3D printed surgical guides after steam sterilization and disinfection by immersion in 70% isopropyl alcohol. The results will provide a basis for developing a protocol for the sterilization of surgical guides.</p></div><div><h3>METHODS</h3><p>A maxillary stone model was scanned with Prime Scan optical scanner (Dentsply Sirona, Charlotte, NC) and the standard tessellation language (STL) file of the model was exported and uploaded to Blue Sky Bio® software. The model was modified to extract tooth #8 digitally in the Blue Sky Bio® software. Surgical guides were designed to extend from tooth number 6 to 10. Forty guides were printed with Formlabs Form 3B+ printer and Formlabs surgical guide resin following manufacturer's instructions. Each guide was scanned with Prime Scan optical scanner before disinfection and sterilization. Twenty guides were individually packaged, and autoclave sterilized at manufacturer's recommendation of 134°C for 20 minutes. The remaining twenty guides were soaked in 70% isopropyl alcohol for fifteen minutes. After sterilization and disinfection, the guides were scanned and STL files from pre- and post-sterilization were compared in GeoMagic Control X software to examine dimensional changes. A paired T-test was done to evaluate distortion of the guide before and after sterilization and disinfection. An unpaired T-test was done to compare the disinfection and sterilization test groups.</p></div><div><h3>RESULTS</h3><p>The average deviation at the lingual, incisal, buccal, combined surfaces, and the entire guide of the sterilized group was 6.28μm, -2.4μm, -20.6μm, 5.6μm, and 12.6μm respectively. The average deviation at the lingual, incisal, buccal, combined surfaces and the entire guide of the chemically disinfected group was -0.43μm, 2.6μm, -0.78μm, 0. μm, and 5.5μm respectively. Paired T-test of the sterilized group showed a significant difference before and after sterilization at all surfaces with p-values <0.05. Paired Ttest of the disinfection group showed no significant difference before and after chemical disinfection at any surface. Unpaired T-test between the sterilized and disinfected group showed a non-significant difference between the incisal and total averages. There was a statistically significant difference between the average deviation of the lingual surfaces with a p-value of 6.31763E-06, the buccal surface with a pvalue of 3.83055E-13, and the combined surfaces with a p-value of .0001.</p></div><div><h3>CONCLUSIONS</h3><p>Results indicate that there is distortion after sterilization and minimal distortion with chemical disinfection. However, the amount of distortion will likely not cause a clinically significant effect on the seating of the surgical guides. This is an indication that surgical guides can be either sterilized or disinfected prior to implant placement.</p></div><div><h3>IMPLICATIONS</h3><p>The results will provide a basis for d
目的检测三维打印手术导板在蒸汽消毒和70%异丙醇浸泡消毒后的变形程度。方法使用 Prime Scan 光学扫描仪(Dentsply Sirona,夏洛特,北卡罗来纳州)扫描上颌结石模型,导出模型的标准细分语言 (STL) 文件并上传到 Blue Sky Bio® 软件。在 Blue Sky Bio® 软件中对模型进行了修改,以便以数字方式拔出 8 号牙齿。手术导板的设计从 6 号牙延伸到 10 号牙。按照制造商的说明,使用 Formlabs Form 3B+ 打印机和 Formlabs 手术导板树脂打印了 40 个导板。在消毒和灭菌前,使用 Prime Scan 光学扫描仪对每枚导板进行扫描。20 个导板单独包装,并在制造商建议的 134°C 高温高压灭菌条件下灭菌 20 分钟。其余 20 个导片在 70% 的异丙醇中浸泡 15 分钟。灭菌和消毒后,在 GeoMagic Control X 软件中扫描导轨并比较灭菌前和灭菌后的 STL 文件,以检查尺寸变化。采用配对 T 检验来评估灭菌和消毒前后导板的变形情况。结果消毒组的舌面、切面、颊面、结合面和整个导板的平均偏差分别为 6.28μm、-2.4μm、-20.6μm、5.6μm 和 12.6μm。化学消毒组的舌面、切面、颊面、合面和整个导板的平均偏差分别为-0.43μm、2.6μm、-0.78μm、0.对消毒组进行的配对 T 检验显示,所有表面在消毒前后均有显著差异,P 值为 <0.05。对消毒组进行的配对 T 检验显示,所有表面在化学消毒前后均无明显差异。消毒组和消毒组之间的非配对 T 检验显示,切缘平均值和总平均值之间的差异不显著。舌侧表面的平均偏差(p 值为 6.31763E-06)、颊侧表面的平均偏差(p 值为 3.83055E-13)和综合表面的平均偏差(p 值为 0.0001)之间存在显著的统计学差异。然而,变形量可能不会对手术导板的就位造成临床上显著的影响。这表明手术导板可以在植入前进行消毒或灭菌处理。
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引用次数: 0
Color Stability Of Various Resin Sealants After Staining Protocol 各种树脂密封剂染色后的颜色稳定性
Pub Date : 2024-09-01 DOI: 10.1016/j.dentre.2024.100118
Danila Dokuchayev, Margareth Rivas, Rafael Rocha Pacheco DDS MDS PhD

OBJECTIVES

Evaluate the color change in various resin sealants when activated by a multi-peak light-curing unit (LCU), in comparison to a flowable resin composite.

METHODS

Four different resin sealants were evaluated: [HS] Helioseal® F Plus (Ivoclar Vivadent), [CP] Clinpro™ (3M™ Oral Care), [GS] Grandio Seal (VOCO GmbH), and [XT] Ultraseal XT™ Hydro (Ultradent Products Inc.). A flowable resin composite (3M™ Filtek™ Supreme Flowable Restorative, A2) was used as control. Using PVS, molds were made from custom 3D-printed models measuring 6.0mm in diameter and 2.0mm in height. Materials were inserted into the molds (n=5), covered by a Mylar® strip, pressed using a microscope slide, and light-activated for 20 seconds using a multi-peak LCU (VALO™ X, Ultradent) in standard mode. All specimens were wet-finished and polished using sandpaper (grits 600 and 1200). The L*, a*, and b* color parameters for each specimen were assessed on both white and black backgrounds using a clinical spectrophotometer (VITA Easyshade®, VITA Zahnfabrik). A staining protocol using black tea was applied. Each specimen was immersed for 24h at 37oC, rinse and dried, and subjected to a 5-minute ultrasonic bath in distilled water. Data was then collected, and ΔE calculated. Statistical analysis was carried out using GraphPad Prism 10.0.2, utilizing ANOVA with a preset alpha of 0.05.

RESULTS

All evaluated resin sealants exhibited a ΔE greater than 11, in contrast to the flowable resin composite that was below 3.5. The b* parameter was most influenced, showing a trend towards yellowing (ordered as HS>XT>GS>CP>FT), followed by a decrease in the L* parameter indicating darkening (GS>XT≥HS≥CP>FT). Finally, the a* parameter experienced minor positive and negative variations.

CONCLUSIONS

Resin sealants demonstrate higher susceptibility to staining than flowable resin composites. Black tea exposure led to a more yellow hue (increased b*) and a darkening effect (reduced L*) in resin sealants.

IMPLICATIONS

Sealants are prone to color changes when exposed to the oral environment, more so than other composite materials or the tooth structure itself. Understanding how this color change occurs is crucial for accurately diagnosing a stained sealant rather than mistaking it for secondary caries. It is noteworthy that different sealants exhibit varying degrees of staining.

目的评估各种树脂封闭剂在多峰值光固化装置(LCU)激活时的颜色变化,并与可流动树脂复合材料进行比较。方法评估四种不同的树脂封闭剂:[HS]Helioseal®F Plus(Ivoclar Vivadent)、[CP]Clinpro™(3M™ Oral Care)、[GS]Grandio Seal(VOCO GmbH)和[XT]Ultraseal XT™ Hydro(Ultradent Products Inc.)可流动树脂复合材料(3M™ Filtek™ Supreme 可流动修复体,A2)用作对照。使用 PVS,用直径 6.0 毫米、高 2.0 毫米的定制 3D 打印模型制作模具。将材料插入模具(n=5),用 Mylar® 条覆盖,用显微镜载玻片压紧,并使用多峰值 LCU(VALO™ X,Ultradent)在标准模式下光照 20 秒。所有试样均使用砂纸(600 和 1200 级)进行湿处理和抛光。使用临床分光光度计(VITA Easyshade®,VITA Zahnfabrik)在白色和黑色背景上评估每个试样的 L*、a* 和 b* 颜色参数。使用红茶进行染色。每个标本在 37 摄氏度下浸泡 24 小时,冲洗并烘干,然后在蒸馏水中进行 5 分钟的超声波浴。然后收集数据并计算 ΔE。使用 GraphPad Prism 10.0.2 进行统计分析,采用方差分析,预设α值为 0.05。结果所有评估的树脂密封剂的ΔE 都大于 11,而可流动树脂复合材料则低于 3.5。b* 参数受到的影响最大,呈现出变黄的趋势(排序为 HS>XT>GS>CP>FT),其次是 L* 参数的下降,表明变暗(GS>XT≥HS≥CP>FT)。最后,a* 参数经历了轻微的正负变化。与红茶接触会导致树脂密封剂的色调变黄(b*增加),颜色变深(L*减少)。 意义密封剂暴露在口腔环境中时容易发生颜色变化,比其他复合材料或牙齿结构本身更容易发生颜色变化。了解这种颜色变化是如何发生的,对于准确诊断染色密封剂而不是误认为是继发性龋齿至关重要。值得注意的是,不同的封闭剂会表现出不同程度的染色。
{"title":"Color Stability Of Various Resin Sealants After Staining Protocol","authors":"Danila Dokuchayev,&nbsp;Margareth Rivas,&nbsp;Rafael Rocha Pacheco DDS MDS PhD","doi":"10.1016/j.dentre.2024.100118","DOIUrl":"10.1016/j.dentre.2024.100118","url":null,"abstract":"<div><h3>OBJECTIVES</h3><p>Evaluate the color change in various resin sealants when activated by a multi-peak light-curing unit (LCU), in comparison to a flowable resin composite.</p></div><div><h3>METHODS</h3><p>Four different resin sealants were evaluated: [HS] Helioseal® F Plus (Ivoclar Vivadent), [CP] Clinpro™ (3M™ Oral Care), [GS] Grandio Seal (VOCO GmbH), and [XT] Ultraseal XT™ Hydro (Ultradent Products Inc.). A flowable resin composite (3M™ Filtek™ Supreme Flowable Restorative, A2) was used as control. Using PVS, molds were made from custom 3D-printed models measuring 6.0mm in diameter and 2.0mm in height. Materials were inserted into the molds (n=5), covered by a Mylar® strip, pressed using a microscope slide, and light-activated for 20 seconds using a multi-peak LCU (VALO™ X, Ultradent) in standard mode. All specimens were wet-finished and polished using sandpaper (grits 600 and 1200). The L*, a*, and b* color parameters for each specimen were assessed on both white and black backgrounds using a clinical spectrophotometer (VITA Easyshade®, VITA Zahnfabrik). A staining protocol using black tea was applied. Each specimen was immersed for 24h at 37oC, rinse and dried, and subjected to a 5-minute ultrasonic bath in distilled water. Data was then collected, and ΔE calculated. Statistical analysis was carried out using GraphPad Prism 10.0.2, utilizing ANOVA with a preset alpha of 0.05.</p></div><div><h3>RESULTS</h3><p>All evaluated resin sealants exhibited a ΔE greater than 11, in contrast to the flowable resin composite that was below 3.5. The b* parameter was most influenced, showing a trend towards yellowing (ordered as HS&gt;XT&gt;GS&gt;CP&gt;FT), followed by a decrease in the L* parameter indicating darkening (GS&gt;XT≥HS≥CP&gt;FT). Finally, the a* parameter experienced minor positive and negative variations.</p></div><div><h3>CONCLUSIONS</h3><p>Resin sealants demonstrate higher susceptibility to staining than flowable resin composites. Black tea exposure led to a more yellow hue (increased b*) and a darkening effect (reduced L*) in resin sealants.</p></div><div><h3>IMPLICATIONS</h3><p>Sealants are prone to color changes when exposed to the oral environment, more so than other composite materials or the tooth structure itself. Understanding how this color change occurs is crucial for accurately diagnosing a stained sealant rather than mistaking it for secondary caries. It is noteworthy that different sealants exhibit varying degrees of staining.</p></div>","PeriodicalId":100364,"journal":{"name":"Dentistry Review","volume":"4 3","pages":"Article 100118"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772559624000415/pdfft?md5=3878970a5ffc05f74723d77ce428db6e&pid=1-s2.0-S2772559624000415-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142169007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Blood Collection for Autologous Blood-Derived Product Preparation: Technique & Application 自体血衍生产品制备的血液采集:技术与应用
Pub Date : 2024-09-01 DOI: 10.1016/j.dentre.2024.100126
Alan George DDS, Thomas Johnson

OBJECTIVES

1. Describe an armamentarium and protocol for safely obtaining blood samples for ABP preparation. 2. Demonstrate sample volumes typically needed in periodontics through case presentation.

METHODS

Patients in this report presented to the Department of Periodontics, Army Postgraduate Dental School (APDS) Postgraduate Dental College, Fort Eisenhower, Georgia. All patients received intravenous cannulation for moderate sedation and elected to provide blood samples for PRF preparation using the described protocol. In all cases, a single 20-gauge intravenous catheter was used for both blood collection and fluid/medication delivery.

CONCLUSIONS

Blood volumes required for ABP preparation amount to a fraction of published recommended total blood draw volume limits. The blood collection method described in this report, which is consistent with published standards of practice, necessitates few additional steps and supplies for practitioners already placing peripheral IV catheters.

IMPLICATIONS

This report serves as a concise protocol for safe and efficient preparation of ABPs that minimizes patient morbidity by utilizing a single intravenous catheter.

目标 1.描述安全获取血液样本以制备 ABP 的方法和规程。2.方法本报告中的患者就诊于佐治亚州艾森豪威尔堡陆军牙科研究生院(APDS)牙科研究生院牙周病学系。所有患者都接受了中度镇静的静脉插管,并选择按照所述方案提供血液样本以制备 PRF。在所有病例中,采血和输液/输药均使用一根 20 号静脉导管。本报告中描述的采血方法符合已公布的实践标准,对于已经置入外周静脉导管的从业人员来说,只需很少的额外步骤和用品。
{"title":"Blood Collection for Autologous Blood-Derived Product Preparation: Technique & Application","authors":"Alan George DDS,&nbsp;Thomas Johnson","doi":"10.1016/j.dentre.2024.100126","DOIUrl":"10.1016/j.dentre.2024.100126","url":null,"abstract":"<div><h3>OBJECTIVES</h3><p>1. Describe an armamentarium and protocol for safely obtaining blood samples for ABP preparation. 2. Demonstrate sample volumes typically needed in periodontics through case presentation.</p></div><div><h3>METHODS</h3><p>Patients in this report presented to the Department of Periodontics, Army Postgraduate Dental School (APDS) Postgraduate Dental College, Fort Eisenhower, Georgia. All patients received intravenous cannulation for moderate sedation and elected to provide blood samples for PRF preparation using the described protocol. In all cases, a single 20-gauge intravenous catheter was used for both blood collection and fluid/medication delivery.</p></div><div><h3>CONCLUSIONS</h3><p>Blood volumes required for ABP preparation amount to a fraction of published recommended total blood draw volume limits. The blood collection method described in this report, which is consistent with published standards of practice, necessitates few additional steps and supplies for practitioners already placing peripheral IV catheters.</p></div><div><h3>IMPLICATIONS</h3><p>This report serves as a concise protocol for safe and efficient preparation of ABPs that minimizes patient morbidity by utilizing a single intravenous catheter.</p></div>","PeriodicalId":100364,"journal":{"name":"Dentistry Review","volume":"4 3","pages":"Article 100126"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S277255962400049X/pdfft?md5=96dcefc39acea51d745ca98be950d74e&pid=1-s2.0-S277255962400049X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142169235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Resin sealant Monomer Conversion using blue laser-diode or blue LED 使用蓝色激光二极管或蓝色发光二极管进行树脂密封剂单体转换
Pub Date : 2024-09-01 DOI: 10.1016/j.dentre.2024.100099
Caroline Dudish, Tori Hayes, Frederick Allen Rueggeberg, Rafael Rocha Pacheco

OBJECTIVES

Evaluate the degree of monomer conversion (DC) of various resin sealants when photocured using a blue laser-diode or commercially available LED light-curing units (LCUs).

METHODS

Three different LCUs were utilized: [LA] blue laser-diode (Monet®, AMD Lasers); [SP] singlepeak blue LED (Elipar™ DeepCure-S, 3M Deutschland GmbH); [MP] multi-peak LED (VALO™ X, Ultradent Products). The spectral irradiance of each LCU was measured using a calibrated integrating sphere/spectral radiometer. Two resin sealants were tested: [CP] Clinpro™ Sealant (3M ESPE) and [XT] UltraSeal XT™ hydro™ (Ultradent Products). Sealants were placed and cured on extracted, human third molars to determine the average sealant clinical thickness: 2.0 mm. Resin sealants (n = 5) were directly dispensed onto the temperature-controlled surface (35oC) of an attenuated total reflectance attachment (Golden Gate; Specac Inc) on a Fourier-transform infrared spectrometer (INVENIO-R, Bruker) inside a custom 3D-printed mold: 2mmh; 5mm-id. LCU distance was standardized at 2.5mm. A Mylar® strip was positioned over the resin sealant for uniform thickness. Exposure durations were defined as: LA-1s, LA-2s, LA-3s, SP-30s, MP-10s (standard mode), and MP-3s (“xtra” mode). The DC (%) was computed using vibrational spectroscopy software (OPUS, Bruker) using peak height ratio changes of aromatic/aliphatic C=C, assessed at five 1-minute intervals. Each resin sealant was exposed using its manufacturer recommended LCU and also with LA. Data analysis was performed using software (GraphPad Prism 10.0.2) employing ANOVA at a pre-set alpha of 0.05.

RESULTS

For each sealant, both SP-30s and MP-10s achieved a higher DC than LA-1s. While SP-30s surpassed LA-2s, MP-10s equaled LA-2. There was no DC difference between LA-3, SP-30s, and MP-10s. MP-3s was not different from LA2s.

CONCLUSIONS

Using manufacturer's suggested LCU and exposure yielded higher DC than a 1-second laser exposure. Extending laser exposure to 3 seconds made DC values comparable. Further research is needed to address clinical ramifications of employing a laser-diode LCU.

IMPLICATIONS

Using the manufacturer-recommended light-curing unit (LCU) and cure duration yielded results similar to those of the 3-second exposure with the LA curing light, but not to the 1-second cure suggested by the LA manufacturer. Employing a 3-second LA curing light method could be a suitable option for placing sealants (small areas) in uncooperative children and patients who would benefit from reduced chair time.

目的评估使用蓝色激光二极管或市售 LED 光固化装置(LCU)进行光固化时各种树脂密封剂的单体转换(DC)程度:[LA] 蓝色激光二极管(Monet®,AMD Lasers);[SP] 单峰值蓝色 LED(Elipar™ DeepCure-S,3M Deutschland GmbH);[MP] 多峰值 LED(VALO™ X,Ultradent Products)。使用校准积分球/光谱辐射计测量每个 LCU 的光谱辐照度。测试了两种树脂密封剂:[CP] Clinpro™ 密封剂(3M ESPE)和[XT] UltraSeal XT™ hydro™(Ultradent Products)。在拔出的人类第三磨牙上放置并固化封闭剂,以确定封闭剂的平均临床厚度:2.0 毫米。将树脂封闭剂(n = 5)直接涂抹在傅立叶变换红外光谱仪(INVENIO-R,布鲁克公司)的衰减全反射附件(Golden Gate;Specac Inc)的温控表面(35oC)上,该附件位于定制的 3D 打印模具内:2mmh;5mm-id。LCU 距离标准化为 2.5mm。在树脂密封剂上放置了一条 Mylar® 带,以保证厚度均匀。曝光持续时间定义为LA-1s、LA-2s、LA-3s、SP-30s、MP-10s(标准模式)和 MP-3s("额外 "模式)。使用振动光谱软件(OPUS,布鲁克公司),利用芳香族/脂肪族 C=C 的峰高比变化计算直流电(%),以 5 次 1 分钟的间隔进行评估。每种树脂密封剂都使用其制造商推荐的 LCU 和 LA 进行暴露。使用软件(GraphPad Prism 10.0.2)进行数据分析,采用方差分析,预设α值为 0.05。结果对于每种密封剂,SP-30 和 MP-10 的 DC 值都高于 LA-1。SP-30 密封剂超过了 LA-2,而 MP-10 密封剂则与 LA-2 相当。LA-3、SP-30 和 MP-10 的直流电没有差异。结论采用制造商建议的 LCU 和曝光可获得比 1 秒激光曝光更高的直流电。将激光照射时间延长至 3 秒可使直流电值相当。意义采用制造商推荐的光固化单元(LCU)和固化持续时间的结果与 LA 固化灯照射 3 秒的结果相似,但与 LA 制造商建议的 1 秒固化结果不同。对于不合作的儿童和需要缩短治疗时间的患者来说,使用 3 秒 LA 固化光的方法可能是一种合适的选择,可用于粘贴密封剂(小面积)。
{"title":"Resin sealant Monomer Conversion using blue laser-diode or blue LED","authors":"Caroline Dudish,&nbsp;Tori Hayes,&nbsp;Frederick Allen Rueggeberg,&nbsp;Rafael Rocha Pacheco","doi":"10.1016/j.dentre.2024.100099","DOIUrl":"10.1016/j.dentre.2024.100099","url":null,"abstract":"<div><h3>OBJECTIVES</h3><p>Evaluate the degree of monomer conversion (DC) of various resin sealants when photocured using a blue laser-diode or commercially available LED light-curing units (LCUs).</p></div><div><h3>METHODS</h3><p>Three different LCUs were utilized: [LA] blue laser-diode (Monet®, AMD Lasers); [SP] singlepeak blue LED (Elipar™ DeepCure-S, 3M Deutschland GmbH); [MP] multi-peak LED (VALO™ X, Ultradent Products). The spectral irradiance of each LCU was measured using a calibrated integrating sphere/spectral radiometer. Two resin sealants were tested: [CP] Clinpro™ Sealant (3M ESPE) and [XT] UltraSeal XT™ hydro™ (Ultradent Products). Sealants were placed and cured on extracted, human third molars to determine the average sealant clinical thickness: 2.0 mm. Resin sealants (n = 5) were directly dispensed onto the temperature-controlled surface (35oC) of an attenuated total reflectance attachment (Golden Gate; Specac Inc) on a Fourier-transform infrared spectrometer (INVENIO-R, Bruker) inside a custom 3D-printed mold: 2mmh; 5mm-id. LCU distance was standardized at 2.5mm. A Mylar® strip was positioned over the resin sealant for uniform thickness. Exposure durations were defined as: LA-1s, LA-2s, LA-3s, SP-30s, MP-10s (standard mode), and MP-3s (“xtra” mode). The DC (%) was computed using vibrational spectroscopy software (OPUS, Bruker) using peak height ratio changes of aromatic/aliphatic C=C, assessed at five 1-minute intervals. Each resin sealant was exposed using its manufacturer recommended LCU and also with LA. Data analysis was performed using software (GraphPad Prism 10.0.2) employing ANOVA at a pre-set alpha of 0.05.</p></div><div><h3>RESULTS</h3><p>For each sealant, both SP-30s and MP-10s achieved a higher DC than LA-1s. While SP-30s surpassed LA-2s, MP-10s equaled LA-2. There was no DC difference between LA-3, SP-30s, and MP-10s. MP-3s was not different from LA2s.</p></div><div><h3>CONCLUSIONS</h3><p>Using manufacturer's suggested LCU and exposure yielded higher DC than a 1-second laser exposure. Extending laser exposure to 3 seconds made DC values comparable. Further research is needed to address clinical ramifications of employing a laser-diode LCU.</p></div><div><h3>IMPLICATIONS</h3><p>Using the manufacturer-recommended light-curing unit (LCU) and cure duration yielded results similar to those of the 3-second exposure with the LA curing light, but not to the 1-second cure suggested by the LA manufacturer. Employing a 3-second LA curing light method could be a suitable option for placing sealants (small areas) in uncooperative children and patients who would benefit from reduced chair time.</p></div>","PeriodicalId":100364,"journal":{"name":"Dentistry Review","volume":"4 3","pages":"Article 100099"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772559624000221/pdfft?md5=d8c42ae748eb6ff31f4dd68c86ad34ef&pid=1-s2.0-S2772559624000221-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142169309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Localized Juvenile Spongiotic Gingival Hyperplasia (LJSGH): A Comprehensive Review 局部幼年海绵状牙龈增生(LJSGH):全面回顾
Pub Date : 2024-09-01 DOI: 10.1016/j.dentre.2024.100111
Emily Summers, Christopher Hollingsworth, Mohammed Bindakhil DDS, MS

OBJECTIVES

Localized Juvenile Spongiotic Gingival Hyperplasia (LJSGH) is a condition characterized by localized, red, and raised gingival lesions with distinct histological findings. The exact etiology of LJSGH has not been established, but trauma and orthodontic treatment have been proposed as possible causes. The aim of this review article is to identify etiologies of this condition and report evidence of which factors are most closely associated with LJSGH.

METHODS

A systematic literature search of the databases Pubmed, EMBASE, and Google Scholar through December 2023 was conducted. 215 subjects across 30 case series/studies were included and a descriptive analysis of data concerning patient demographics, clinical presentation, and treatment was conducted. Prevalence of potential etiologic contributors was also noted.

RESULTS

The review yielded 215 subjects, 110 males (51.2%) and 105 females (48.8%). The age was reported in 135 participants, with a mean age of 14.9 (Median= 12, SD= 11.14). Lesions were solitary in 94.0% of the cases (n= 202) and 86% of the cases (n=197) occurred on the maxilla, with 93.4% (n= 214) of lesions affecting the anterior portions of the gingiva. The facial surface of the gingiva was involved in 90.8% of the cases (n=208). The most common treatment for LJSGH was surgical excision (71%, n=87) followed by biofilm control and observation (13.9%, n= 17). Most lesions were not concurrent with orthodontic treatment (86.3%, n=107). In addition, other types of traumas preceding the lesions, such as dental extractions, were reported in only two patients.

CONCLUSIONS

Despite growing interest over the last couple of decades regarding LJSGH, it is still a poorly understood and underreported condition. Further research is required to better understand the disease process and how to treat it.

IMPLICATIONS

By highlighting the most prevalent etiological factors, clinical patterns, and treatment modalities associated with LJSGH throughout the current literature, this review may serve as a comprehensive resource for the disease process.

目的局部幼年海绵状牙龈增生(LJSGH)是一种以局部、红色和隆起的牙龈病变为特征的疾病,具有明显的组织学特征。LJSGH 的确切病因尚未确定,但外伤和正畸治疗被认为是可能的病因。本综述文章旨在确定该病症的病因,并报告哪些因素与 LJSGH 关系最为密切。方法截至 2023 年 12 月,对 Pubmed、EMBASE 和 Google Scholar 等数据库进行了系统的文献检索。共纳入了 30 个病例系列/研究中的 215 个受试者,并对患者人口统计学、临床表现和治疗等相关数据进行了描述性分析。结果研究共纳入 215 名受试者,其中男性 110 名(51.2%),女性 105 名(48.8%)。135人报告了年龄,平均年龄为14.9岁(中位数= 12岁,标准差= 11.14岁)。94.0%的病例(n= 202)为单发,86%的病例(n=197)发生在上颌骨,93.4%的病例(n= 214)影响牙龈前部。90.8%的病例(n=208)累及牙龈的面部表面。LJSGH最常见的治疗方法是手术切除(71%,n=87),其次是生物膜控制和观察(13.9%,n=17)。大多数病变与正畸治疗无关(86.3%,n=107)。结论尽管过去几十年来人们对 LJSGH 的兴趣与日俱增,但对它的了解仍然很少,报告也不足。通过强调当前文献中与 LJSGH 相关的最普遍病因、临床模式和治疗方法,本综述可作为该疾病过程的综合资料。
{"title":"Localized Juvenile Spongiotic Gingival Hyperplasia (LJSGH): A Comprehensive Review","authors":"Emily Summers,&nbsp;Christopher Hollingsworth,&nbsp;Mohammed Bindakhil DDS, MS","doi":"10.1016/j.dentre.2024.100111","DOIUrl":"10.1016/j.dentre.2024.100111","url":null,"abstract":"<div><h3>OBJECTIVES</h3><p>Localized Juvenile Spongiotic Gingival Hyperplasia (LJSGH) is a condition characterized by localized, red, and raised gingival lesions with distinct histological findings. The exact etiology of LJSGH has not been established, but trauma and orthodontic treatment have been proposed as possible causes. The aim of this review article is to identify etiologies of this condition and report evidence of which factors are most closely associated with LJSGH.</p></div><div><h3>METHODS</h3><p>A systematic literature search of the databases Pubmed, EMBASE, and Google Scholar through December 2023 was conducted. 215 subjects across 30 case series/studies were included and a descriptive analysis of data concerning patient demographics, clinical presentation, and treatment was conducted. Prevalence of potential etiologic contributors was also noted.</p></div><div><h3>RESULTS</h3><p>The review yielded 215 subjects, 110 males (51.2%) and 105 females (48.8%). The age was reported in 135 participants, with a mean age of 14.9 (Median= 12, SD= 11.14). Lesions were solitary in 94.0% of the cases (n= 202) and 86% of the cases (n=197) occurred on the maxilla, with 93.4% (n= 214) of lesions affecting the anterior portions of the gingiva. The facial surface of the gingiva was involved in 90.8% of the cases (n=208). The most common treatment for LJSGH was surgical excision (71%, n=87) followed by biofilm control and observation (13.9%, n= 17). Most lesions were not concurrent with orthodontic treatment (86.3%, n=107). In addition, other types of traumas preceding the lesions, such as dental extractions, were reported in only two patients.</p></div><div><h3>CONCLUSIONS</h3><p>Despite growing interest over the last couple of decades regarding LJSGH, it is still a poorly understood and underreported condition. Further research is required to better understand the disease process and how to treat it.</p></div><div><h3>IMPLICATIONS</h3><p>By highlighting the most prevalent etiological factors, clinical patterns, and treatment modalities associated with LJSGH throughout the current literature, this review may serve as a comprehensive resource for the disease process.</p></div>","PeriodicalId":100364,"journal":{"name":"Dentistry Review","volume":"4 3","pages":"Article 100111"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772559624000348/pdfft?md5=8e9fd6b4585746cf8789469e2e510519&pid=1-s2.0-S2772559624000348-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142168737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality Assurance- Most Common Reasons for Rejection 质量保证--最常见的拒收原因
Pub Date : 2024-09-01 DOI: 10.1016/j.dentre.2024.100100
William Gladden

OBJECTIVES

Define Quality Assurance (QA) & classify reasons for rejection of removable prosthodontic restorations during faculty QA review in predoctoral student clinic. Develop learning aids to make students aware of the most common reasons and how to avoid them.

METHODS

Three-year retrospective analysis of reasons for rejection during QA review of student's planned restorations. Categories of failure were organized in rank order.

RESULTS

Reasons for rejection in rank order: (1) Work Auth./Misc. (2) Impression (3) Casts/Articulation (4) Prep Design (5) Working Dies

CONCLUSIONS

QA is an integral part of predoctoral dental education, helping students to develop critical appraisal skills of restoration work. Learning aids developed from a student perspective may help students pre-emptively correct and avoid similar errors in the clinical setting.

IMPLICATIONS

Results of this analysis will make students more aware of and may help mitigate future errors in these categories, improving workflow within the clinic.

目的定义质量保证(QA)&amp;对在博士前期学生诊所中教师进行质量保证审查时可摘义齿修复体被拒绝的原因进行分类。方法:对学生计划修复体的质量保证审查中被拒绝的原因进行为期三年的回顾性分析。结果排序如下:(1) 工作授权/其他 (2) 印模 (3) 铸件/压痕 (4) 预备设计 (5) 工作模具CONCLUSIONSQA是口腔医学博士前期教育不可或缺的一部分,可以帮助学生发展对修复工作的批判性评价技能。从学生角度开发的学习辅助工具可以帮助学生在临床环境中预先纠正和避免类似的错误。
{"title":"Quality Assurance- Most Common Reasons for Rejection","authors":"William Gladden","doi":"10.1016/j.dentre.2024.100100","DOIUrl":"10.1016/j.dentre.2024.100100","url":null,"abstract":"<div><h3>OBJECTIVES</h3><p>Define Quality Assurance (QA) &amp; classify reasons for rejection of removable prosthodontic restorations during faculty QA review in predoctoral student clinic. Develop learning aids to make students aware of the most common reasons and how to avoid them.</p></div><div><h3>METHODS</h3><p>Three-year retrospective analysis of reasons for rejection during QA review of student's planned restorations. Categories of failure were organized in rank order.</p></div><div><h3>RESULTS</h3><p>Reasons for rejection in rank order: (1) Work Auth./Misc. (2) Impression (3) Casts/Articulation (4) Prep Design (5) Working Dies</p></div><div><h3>CONCLUSIONS</h3><p>QA is an integral part of predoctoral dental education, helping students to develop critical appraisal skills of restoration work. Learning aids developed from a student perspective may help students pre-emptively correct and avoid similar errors in the clinical setting.</p></div><div><h3>IMPLICATIONS</h3><p>Results of this analysis will make students more aware of and may help mitigate future errors in these categories, improving workflow within the clinic.</p></div>","PeriodicalId":100364,"journal":{"name":"Dentistry Review","volume":"4 3","pages":"Article 100100"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772559624000233/pdfft?md5=c75f2c6148a23d2031a7ab1fb93aa812&pid=1-s2.0-S2772559624000233-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142169310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of local administration of doxycycline on bone regeneration/formation: A systematic review 局部使用强力霉素对骨质再生/形成的影响:系统综述
Pub Date : 2024-08-22 DOI: 10.1016/j.dentre.2024.100148
Tatiane Cristina Dotta , Michelle Chang , Hian Parize , Fellipe Augusto Tocchini de Figueiredo , Hugo Gaêta-Araujo , Dalva Cruz Laganá , Johannes Kleinheinz , Vinicius Pedrazzi

Objective

To evaluate the effects of local administration of doxycycline on bone regeneration and formation.

Design

An electronic search was conducted in the PubMed, EMBASE, Scopus, Web of Science, and Cochrane Library databases from November 2023 to July 2024. Human and animals’ studies that assessed the local effect of doxycycline on bone formation and regeneration using histological and histomorphometric measures were included. The risk of bias was evaluated using the Joanna Briggs Institute (JBI) Critical Appraisal Tool for quasiexperimental studies. This review was registered in the PROSPERO database (CRD42024516306).

Results

Of the 23 studies selected for full-text analysis, five were deemed eligible for this review. No human clinical trials were found. The studies included evaluations of 94 rats, 28 rabbits, and 6 dogs. The histological and histomorphometric methods used varied among the studies. Limitations of the evidence included the heterogeneity of the analyses and the methodologies of the included studies.

Conclusions

The findings suggest that doxycycline may promote local bone formation and repair, and that its combination with other substances may enhance these effects in animal models. However, further translational research is required to confirm these results accurately and extend their applicability to human clinical studies.

设计2023年11月至2024年7月,在PubMed、EMBASE、Scopus、Web of Science和Cochrane图书馆数据库中进行了电子检索。纳入了使用组织学和组织形态计量学方法评估强力霉素对骨形成和再生的局部影响的人类和动物研究。采用乔安娜-布里格斯研究所(Joanna Briggs Institute,JBI)的准实验研究关键评估工具对偏倚风险进行了评估。本综述已在 PROSPERO 数据库(CRD42024516306)中注册。没有发现人体临床试验。这些研究包括对 94 只大鼠、28 只兔子和 6 只狗的评估。不同研究采用的组织学和组织形态计量学方法各不相同。结论研究结果表明,强力霉素可促进局部骨形成和修复,与其他物质联合使用可增强动物模型的这些效果。然而,要想准确证实这些结果并将其应用于人体临床研究,还需要进一步的转化研究。
{"title":"Effect of local administration of doxycycline on bone regeneration/formation: A systematic review","authors":"Tatiane Cristina Dotta ,&nbsp;Michelle Chang ,&nbsp;Hian Parize ,&nbsp;Fellipe Augusto Tocchini de Figueiredo ,&nbsp;Hugo Gaêta-Araujo ,&nbsp;Dalva Cruz Laganá ,&nbsp;Johannes Kleinheinz ,&nbsp;Vinicius Pedrazzi","doi":"10.1016/j.dentre.2024.100148","DOIUrl":"10.1016/j.dentre.2024.100148","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the effects of local administration of doxycycline on bone regeneration and formation.</p></div><div><h3>Design</h3><p>An electronic search was conducted in the PubMed, EMBASE, Scopus, Web of Science, and Cochrane Library databases from November 2023 to July 2024. Human and animals’ studies that assessed the local effect of doxycycline on bone formation and regeneration using histological and histomorphometric measures were included. The risk of bias was evaluated using the Joanna Briggs Institute (JBI) Critical Appraisal Tool for quasiexperimental studies. This review was registered in the PROSPERO database (CRD42024516306).</p></div><div><h3>Results</h3><p>Of the 23 studies selected for full-text analysis, five were deemed eligible for this review. No human clinical trials were found. The studies included evaluations of 94 rats, 28 rabbits, and 6 dogs. The histological and histomorphometric methods used varied among the studies. Limitations of the evidence included the heterogeneity of the analyses and the methodologies of the included studies.</p></div><div><h3>Conclusions</h3><p>The findings suggest that doxycycline may promote local bone formation and repair, and that its combination with other substances may enhance these effects in animal models. However, further translational research is required to confirm these results accurately and extend their applicability to human clinical studies.</p></div>","PeriodicalId":100364,"journal":{"name":"Dentistry Review","volume":"4 3","pages":"Article 100148"},"PeriodicalIF":0.0,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772559624000713/pdfft?md5=9abf931e7c247ae9ff08c8eabeb34cae&pid=1-s2.0-S2772559624000713-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142048164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What is the current state of the art in incorporating antimicrobial agents into conventional glass ionomer cement? A systematic review 在传统玻璃离子聚合物水泥中加入抗菌剂的技术现状如何?系统回顾
Pub Date : 2024-08-13 DOI: 10.1016/j.dentre.2024.100149
Germano C. Dutra , Simone Kreve , Andréa C. Reis

Statement of problem

Conventional glass ionomer cement has limited action on biofilm. Thus, studies seek to incorporate different antimicrobial agents into GIC to provide antimicrobial activity.

Purpose

The purpose of this systematic review was to review the current state of research regarding different antimicrobial agents incorporated into conventional GIC.

Material and method

Searches were conducted in the SCOPUS, PubMed/Medline, EMBASE, Web of Science, and Google Scholar databases using the terms: glass ionomer cement; anti-microbial agent; anti-infective agents; antimicrobial; hydrochloride, chlorhexidine; microbicide; agents, anti-infective; antibacterial. The risk of bias was performed by adaptation of the Joanna Briggs Institute's assessment instrument for quasi-experimental studies.

Results

A total of 798 articles were found in the databases, of which 242 were duplicates. Fifty-nine papers were eligible to be read in full, and 51 were included in this systematic review.

Conclusion

Different antimicrobial agents are studied and incorporated into the GIC. However, based on the studies included in this systematic review, no fully effective agent was found that could maintain the prolonged antimicrobial effect without causing harm to the GIC or the body.

问题陈述传统的玻璃离聚体水泥对生物膜的作用有限。因此,研究人员试图在 GIC 中加入不同的抗菌剂,以提供抗菌活性。目的本系统综述旨在回顾有关传统 GIC 中加入不同抗菌剂的研究现状。材料和方法在 SCOPUS、PubMed/Medline、EMBASE、Web of Science 和 Google Scholar 数据库中使用以下术语进行了搜索:玻璃离子水泥;抗微生物剂;抗感染剂;抗菌剂;盐酸,洗必泰;杀微生物剂;抗感染剂;抗菌剂。结果 在数据库中共找到 798 篇文章,其中 242 篇为重复文章。有 59 篇论文符合全文阅读条件,其中 51 篇被纳入本系统综述。然而,根据本系统综述所纳入的研究,没有发现一种完全有效的制剂可以在不对 GIC 或人体造成伤害的情况下保持长期的抗菌效果。
{"title":"What is the current state of the art in incorporating antimicrobial agents into conventional glass ionomer cement? A systematic review","authors":"Germano C. Dutra ,&nbsp;Simone Kreve ,&nbsp;Andréa C. Reis","doi":"10.1016/j.dentre.2024.100149","DOIUrl":"10.1016/j.dentre.2024.100149","url":null,"abstract":"<div><h3>Statement of problem</h3><p>Conventional glass ionomer cement has limited action on biofilm. Thus, studies seek to incorporate different antimicrobial agents into GIC to provide antimicrobial activity.</p></div><div><h3>Purpose</h3><p>The purpose of this systematic review was to review the current state of research regarding different antimicrobial agents incorporated into conventional GIC.</p></div><div><h3>Material and method</h3><p>Searches were conducted in the SCOPUS, PubMed/Medline, EMBASE, Web of Science, and Google Scholar databases using the terms: glass ionomer cement; anti-microbial agent; anti-infective agents; antimicrobial; hydrochloride, chlorhexidine; microbicide; agents, anti-infective; antibacterial. The risk of bias was performed by adaptation of the Joanna Briggs Institute's assessment instrument for quasi-experimental studies.</p></div><div><h3>Results</h3><p>A total of 798 articles were found in the databases, of which 242 were duplicates. Fifty-nine papers were eligible to be read in full, and 51 were included in this systematic review.</p></div><div><h3>Conclusion</h3><p>Different antimicrobial agents are studied and incorporated into the GIC. However, based on the studies included in this systematic review, no fully effective agent was found that could maintain the prolonged antimicrobial effect without causing harm to the GIC or the body.</p></div>","PeriodicalId":100364,"journal":{"name":"Dentistry Review","volume":"4 3","pages":"Article 100149"},"PeriodicalIF":0.0,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772559624000725/pdfft?md5=2728d666cddccbf74ae6bbeb091e6aa7&pid=1-s2.0-S2772559624000725-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141997630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Dentistry Review
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