Pub Date : 2021-10-01DOI: 10.13604/J.CNKI.46-1064/R.2021.10.02
Liang Li-ting, Yang Li-juan, LU Zhuang-nian, Liu Yun-guang, Lin Na
Objective To explore the distribution characteristics of rs3819024 and rs2275913 polymorphisms of interleukin-17A (IL-17A) gene in Black-clothes Zhuang population in Guangxi and the polymorphism different among ethnic populations. Methods The polymorphisms of rs3819024 and rs2275913 of IL-17A gene in 115 Black-clothes Zhuang subjects were genotyped by SNaPshot technique. And used statistical methods to compare the differences in the distribution of these polymorphisms across sexes and populations. Results There were AA, AG and GG genotypes at rs3819024 and rs2275913 of IL-17A gene of Black-clothes Zhuang population in Guangxi, and AG genotype was the most common genotype in both loci. The frequencies of AA, AG and GG genotypes at rs3819024 were 15.6%, 54.8% and 29.6%, respectively, and the frequencies of AA, AG and GG genotypes at rs2275913 were 27.8%, 51.3% and 20.9%, respectively. G and A alleles were commonly found at rs3819024 and rs2275913, respectively, and their distribution frequencies were 57.0% and 53.5%, respectively. The genotype and allele frequency of rs3819024 and rs2275913 had no significant difference between male and female ( P>0.05). The genotype and allele of rs3819024 were significantly different from Japanese in Tokyo, Japan (JPT), Yoruba in Ibadan, Nigeria (YRI), Gujarati Indians in Houston (GIH) and Utah residents with Northern and Western European ancestry from the CEPH collection (CEU) populations published by the 1000 Genome Project (all P<0.05). There was no statistically significant different from Han Chinese in Beijing, China (CHB) population ( P>0.05)。The distribution frequency of each genotype and allele at rs2275913 site were significantly different from YRI, GIH and CEU ( P<0.05), and there was no statistically significant different from HCB ( P>0.05). Compared with JPT, the difference in genotype distribution frequency was not statistically significant ( P<0.05), but the difference in allele distribution frequency was statistically significant ( P<0.05). Conclusion The locus polymorphisms of rs3819024 and rs2275913 of IL-17A gene have difference among different races and regions. 摘要： 目的 探讨广西黑衣壮人群白细胞介素 17A 基因 ( IL-17A) rs3819024、rs2275913 位点的多态性分布特点和 不同人群间的多态性差异。 方法 采取多重单碱基延伸法 (SNaPshot) 方法对 115 例广西黑衣壮人群 IL-17A 基因 rs3819024、rs2275913 位点进行基因分型检测, 并比较不同性别及人群分布差异。 结果 广西黑衣壮人群 IL-17A 基因 rs3819024 和 rs2275913 位点均存在 AA、AG、GG 3 种基因型, 两位点基因型分布均以 AG 基因型多见, 其中 rs3819024 位 点 AA、AG、GG 基因型的分布频率分别为 15.6%、54.8%、29.6%; rs2275913 位点 AA、AG、GG 基因型的分布频率分别为 27.8%、51.3%、20.9%。rs3819024 和 rs2275913 位点分别以 G 和 A 等位基因多见, 分布频率分别为 57.0% 和 53.5%。rs3819024 和 rs2275913 两位点基因型及等位基因频率在广西黑衣壮人群男女性别间比较, 差异无统计学意义 ( P>0.05)。rs3819024 位点基因型及等位基因频率与千人基因组计划 (1000 Genomes) 数据库公布的日本人群 (JPT)、非洲 尼日利亚人群 (YRI)、印第安人群 (GIH)、欧洲人群 (CEU) 比较, 差异均有统计学意义 ( P<0.05); 与北京汉族人群 (HCB) 比较差异无统计学意义 ( P>0.05)。rs2275913 位点基因型及等位基因频率与 YRI、GIH、CEU 人群比较差异均有统计学 意义 ( P<0.05), 与 HCB 人群比较差异无统计学意义 ( P>0.05); 而与 JPT 人群相比, 基因型频率差异无统计学意义 ( P>0.05)
{"title":"Genetic polymorphisms of interluekin-17A gene in Black-clothes Zhuang population in Guangxi","authors":"Liang Li-ting, Yang Li-juan, LU Zhuang-nian, Liu Yun-guang, Lin Na","doi":"10.13604/J.CNKI.46-1064/R.2021.10.02","DOIUrl":"https://doi.org/10.13604/J.CNKI.46-1064/R.2021.10.02","url":null,"abstract":"Objective To explore the distribution characteristics of rs3819024 and rs2275913 polymorphisms\u0000 of interleukin-17A (IL-17A) gene in Black-clothes Zhuang population in Guangxi and\u0000 the polymorphism different among ethnic populations.\u0000 Methods The polymorphisms of rs3819024 and rs2275913 of IL-17A gene in 115 Black-clothes\u0000 Zhuang subjects were genotyped by SNaPshot technique. And used statistical methods\u0000 to compare the differences in the distribution of these polymorphisms across sexes\u0000 and populations.\u0000 Results There were AA, AG and GG genotypes at rs3819024 and rs2275913 of IL-17A gene of Black-clothes\u0000 Zhuang population in Guangxi, and AG genotype was the most common genotype in both\u0000 loci. The frequencies of AA, AG and GG genotypes at rs3819024 were 15.6%, 54.8% and\u0000 29.6%, respectively, and the frequencies of AA, AG and GG genotypes at rs2275913 were\u0000 27.8%, 51.3% and 20.9%, respectively. G and A alleles were commonly found at rs3819024\u0000 and rs2275913, respectively, and their distribution frequencies were 57.0% and 53.5%,\u0000 respectively. The genotype and allele frequency of rs3819024 and rs2275913 had no\u0000 significant difference between male and female (\u0000 P>0.05). The genotype and allele of rs3819024 were significantly different from Japanese\u0000 in Tokyo, Japan (JPT), Yoruba in Ibadan, Nigeria (YRI), Gujarati Indians in Houston\u0000 (GIH) and Utah residents with Northern and Western European ancestry from the CEPH\u0000 collection (CEU) populations published by the 1000 Genome Project (all P<0.05). There was no statistically significant different from Han Chinese in Beijing,\u0000 China (CHB) population (\u0000 P>0.05)。The distribution frequency of each genotype and allele at rs2275913 site were\u0000 significantly different from YRI, GIH and CEU (\u0000 P<0.05), and there was no statistically significant different from HCB (\u0000 P>0.05). Compared with JPT, the difference in genotype distribution frequency was not\u0000 statistically significant (\u0000 P<0.05), but the difference in allele distribution frequency was statistically significant\u0000 (\u0000 P<0.05).\u0000 Conclusion The locus polymorphisms of rs3819024 and rs2275913 of IL-17A gene have difference\u0000 among different races and regions.\u0000 摘要： 目的 探讨广西黑衣壮人群白细胞介素 17A 基因 (\u0000 IL-17A) rs3819024、rs2275913 位点的多态性分布特点和 不同人群间的多态性差异。\u0000 方法 采取多重单碱基延伸法 (SNaPshot) 方法对 115 例广西黑衣壮人群 IL-17A 基因 rs3819024、rs2275913 位点进行基因分型检测, 并比较不同性别及人群分布差异。\u0000 结果 广西黑衣壮人群 IL-17A 基因 rs3819024 和 rs2275913 位点均存在 AA、AG、GG 3 种基因型, 两位点基因型分布均以 AG 基因型多见, 其中 rs3819024\u0000 位 点 AA、AG、GG 基因型的分布频率分别为 15.6%、54.8%、29.6%; rs2275913 位点 AA、AG、GG 基因型的分布频率分别为 27.8%、51.3%、20.9%。rs3819024\u0000 和 rs2275913 位点分别以 G 和 A 等位基因多见, 分布频率分别为 57.0% 和 53.5%。rs3819024 和 rs2275913 两位点基因型及等位基因频率在广西黑衣壮人群男女性别间比较,\u0000 差异无统计学意义 (\u0000 P>0.05)。rs3819024 位点基因型及等位基因频率与千人基因组计划 (1000 Genomes) 数据库公布的日本人群 (JPT)、非洲 尼日利亚人群 (YRI)、印第安人群\u0000 (GIH)、欧洲人群 (CEU) 比较, 差异均有统计学意义 (\u0000 P<0.05); 与北京汉族人群 (HCB) 比较差异无统计学意义 (\u0000 P>0.05)。rs2275913 位点基因型及等位基因频率与 YRI、GIH、CEU 人群比较差异均有统计学 意义 (\u0000 P<0.05), 与 HCB 人群比较差异无统计学意义 (\u0000 P>0.05); 而与 JPT 人群相比, 基因型频率差异无统计学意义 (\u0000 P>0.05)","PeriodicalId":10045,"journal":{"name":"中国热带医学","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91039452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective To retrospectively analyze 2 foodborne disease outbreaks caused by Salmonella putten in Hefei, and we explore the relationship and causes of the 2 outbreaks, so as to provide scientific basis for the prevention and treatment of similar outbreaks in the future. Methods Field epidemiological surveys were conducted on the patients found in the outbreaks, hygienic surveys were conducted in the places where the outbreaks happened, the results were analyzed by descriptive analysis, specimens of surplus food, suspicious food and anal swabs of patients were collected for microbiological testing, the homology of strains was analyzed by pulsed-field gel electrophoresis (PFGE). Results Five cases were found in the outbreak A, and 6 cases were found in the outbreak B, all cases had eaten a same brand of braised chicken in the outbreak, the main clinical manifestations were diarrhea, fever, headache, nausea, some patients had abdominal pain and vomiting; the total viable counts of the same batch unopened food was 3.0×10 8 CFU/g, and the coliform counts was 3.5×10 7 CFU/g; The Salmonella putten was detected from 1 surplus food, 1 suspicious same batch unopened food, and 6 anal swabs of cases, which had homology by PFGE molecular typing analysis, there were 7 strains of the Salmonella putten, with a similar scale of 100%, and 1 strain of another suspicious same batch unopened food, with a similar scale of 94.64%, with high homology. Conclusion Combined with field epidemiological surveys, hygienic surveys, clinical manifestations and microbiological testing results, the two events were foodborne disease outbreaks caused by the same Salmonella putten. 摘要： 目的 回顾性分析合肥市接连调査的两起普顿沙门菌引起的食源性疾病事件, 探讨两起事件发生的联系与 原因, 为今后预防和处置类似事件提供科学依据。 方法 对在事件发生地搜索到的患者进行现场流行病学调査, 事件 发生地开展现场卫生学调査, 调査结果采用描述性分析; 采集剩余食品、可疑食品及病例肛拭子标本进行微生物学检 验, 运用脉冲场凝胶电泳(PFGE), 分析菌株的同源性。 结果 A事件发现5例病例, B事件发现6例病例, 所有病例均曾 在事件中食用过某同一品牌烧鸡, 主要临床表现为腹泻、发热、头痛、恶心, 部分病例伴有腹痛、呕吐; 可疑食品同批次 未拆封食品中的菌落总数测定结果为3.0×10 8 CFU/g, 大肠菌群计数结果为3.5×10 7 CFU/g;在1份剩余食品、1份可疑食 品同批次未拆封食品、份病例肛拭子中均检出普顿沙门菌, 经PFGE分子分型分析, 7株普顿沙门菌分子分型图谱相似 度为100%, 另1份可疑食品同批次未拆封食品中检出的普顿沙门菌分子分型图谱与其余7株相似度为94.64%, 具有髙 度同源性。 结论 结合现场流行病学调査、现场卫生学调査、病例临床表现及实验室检验结果综合分析, 两起事件均 是由于患者食用了同一品牌变质烧鸡, 由同一种普顿沙门菌引起的食源性疾病事件。
{"title":"Two foodborne disease outbreaks caused by Salmonella putten","authors":"Hou Yong, Guan Heng-yan, Han Hong-mei, Wu Si-yuan, Yue-Ju Feng, Fang Zheng","doi":"10.13604/J.CNKI.46-1064/R.2021.10.11","DOIUrl":"https://doi.org/10.13604/J.CNKI.46-1064/R.2021.10.11","url":null,"abstract":"Objective To retrospectively analyze 2 foodborne disease outbreaks caused by Salmonella putten in Hefei, and we explore the relationship and causes of the 2 outbreaks, so as to\u0000 provide scientific basis for the prevention and treatment of similar outbreaks in\u0000 the future.\u0000 Methods Field epidemiological surveys were conducted on the patients found in the outbreaks,\u0000 hygienic surveys were conducted in the places where the outbreaks happened, the results\u0000 were analyzed by descriptive analysis, specimens of surplus food, suspicious food\u0000 and anal swabs of patients were collected for microbiological testing, the homology\u0000 of strains was analyzed by pulsed-field gel electrophoresis (PFGE).\u0000 Results Five cases were found in the outbreak A, and 6 cases were found in the outbreak B,\u0000 all cases had eaten a same brand of braised chicken in the outbreak, the main clinical\u0000 manifestations were diarrhea, fever, headache, nausea, some patients had abdominal\u0000 pain and vomiting; the total viable counts of the same batch unopened food was 3.0×10\u0000 8 CFU/g, and the coliform counts was 3.5×10\u0000 7 CFU/g; The Salmonella putten was detected from 1 surplus food, 1 suspicious same batch unopened food, and 6 anal\u0000 swabs of cases, which had homology by PFGE molecular typing analysis, there were 7\u0000 strains of the Salmonella putten, with a similar scale of 100%, and 1 strain of another suspicious same batch unopened\u0000 food, with a similar scale of 94.64%, with high homology.\u0000 Conclusion Combined with field epidemiological surveys, hygienic surveys, clinical manifestations\u0000 and microbiological testing results, the two events were foodborne disease outbreaks\u0000 caused by the same Salmonella putten.\u0000 摘要： 目的 回顾性分析合肥市接连调査的两起普顿沙门菌引起的食源性疾病事件, 探讨两起事件发生的联系与 原因, 为今后预防和处置类似事件提供科学依据。\u0000 方法 对在事件发生地搜索到的患者进行现场流行病学调査, 事件 发生地开展现场卫生学调査, 调査结果采用描述性分析; 采集剩余食品、可疑食品及病例肛拭子标本进行微生物学检\u0000 验, 运用脉冲场凝胶电泳(PFGE), 分析菌株的同源性。\u0000 结果 A事件发现5例病例, B事件发现6例病例, 所有病例均曾 在事件中食用过某同一品牌烧鸡, 主要临床表现为腹泻、发热、头痛、恶心, 部分病例伴有腹痛、呕吐; 可疑食品同批次\u0000 未拆封食品中的菌落总数测定结果为3.0×10\u0000 8 CFU/g, 大肠菌群计数结果为3.5×10\u0000 7 CFU/g;在1份剩余食品、1份可疑食 品同批次未拆封食品、份病例肛拭子中均检出普顿沙门菌, 经PFGE分子分型分析, 7株普顿沙门菌分子分型图谱相似 度为100%,\u0000 另1份可疑食品同批次未拆封食品中检出的普顿沙门菌分子分型图谱与其余7株相似度为94.64%, 具有髙 度同源性。\u0000 结论 结合现场流行病学调査、现场卫生学调査、病例临床表现及实验室检验结果综合分析, 两起事件均 是由于患者食用了同一品牌变质烧鸡, 由同一种普顿沙门菌引起的食源性疾病事件。","PeriodicalId":10045,"journal":{"name":"中国热带医学","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79794310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-01DOI: 10.13604/j.cnki.46-1064/r.2021.05.04
Chen Shao-ming, Qiu Li, Su Xin-yuan, Jia Pen-ben, Feng Fan-li, Luo Yan, Chen Jing-jing, Lao Shi-jun, Yan Xiu-juan, Qiu Ren, Wang Nan-lai, Jin Yun-ming, He Bin, Chen Yan
Objective To introduce the process and concrete steps of making dynamic interactive disease map using Leaflet program package of R software, and we provide assistance for demonstrating the regional distribution of the disease, epidemic analysis and field disposal. Methods The address, case classification and date of onset of coronavirus disease 2019 (COVID-19) cases, including confirmed and asymptomatic cases, in Hainan as of August 30, 2020 were collected by Infectious Diseases Reporting System. The addresses of cases were input into Amap coordinate pickup system to get the latitude and longitude coordinates of the addresses. Amap and Esri map were created as base layers, and case markers, function for case clusters and measurement tools were created by leaflet package. Results Dynamic interactive map of COVID-19 created by R software could be dragged, be zoomed in and out. It can be switched between administrative division map and satellite map. The numbers, addresses, onset date and other information could be display by clicking the cases in the map. The map can be shared with interested researchers as an html file. The distance between any cases or between the case and the suspected exposure location could be measured. Conclusion As a free and open source software, R software can easily and flexibly make dynamic interactive maps of diseases, intuitively and comprehensively display the regional distribution of diseases. It It plays a very helpful role in analyzing the transmission process of infectious diseases and the on-site treatment of the epidemic situation, which is worthy of promotion and application in epidemiology investigation and survey research. 摘要：目的 介绍使用R软件leaflet程序包制作疾病动态交互地图的 方法 和具体步骤, 为展示疾病的地区分布、疫 情的分析和现场处置提供帮助。 方法 通过传染病信息报告系统收集海南省截至2020年8月30日新型冠状病毒肺炎 确诊病例和无症状感染者地址、病例分类、发病日期等资料。将病例地址录人髙德地图坐标拾取系统, 获取病例地址 的经纬度坐标。利用R软件leaflet程序包调用髙德地图、Esri卫星地图做为底图, 添加病例标记, 病例聚合功能及测量 工具。 结果 R软件制作的海南省新冠病毒动态交互地图可以实现放大、缩小、拖拽等操作, 可以切换行政区划地图和 卫星地图, 点击病例可以显示病例序号, 现住址和发病日期等信息, 可将地图以html文件方式分享给相关研究人员, 并 可以测量病例间或病例与可疑暴露地点间的距离。 结论 R软件作为一款免费、开源的软件, 可以简便、灵活的制作 疾病动态交互地图, 直观、全面的展示疾病的地区分布, 对于分析传染病的传播过程、疫情的现场处置起到很好的辅助 作用, 在流行病学调査研究中值得推广应用。
{"title":"Making the dynamic interactive map of COVID-19 by implementation of R software","authors":"Chen Shao-ming, Qiu Li, Su Xin-yuan, Jia Pen-ben, Feng Fan-li, Luo Yan, Chen Jing-jing, Lao Shi-jun, Yan Xiu-juan, Qiu Ren, Wang Nan-lai, Jin Yun-ming, He Bin, Chen Yan","doi":"10.13604/j.cnki.46-1064/r.2021.05.04","DOIUrl":"https://doi.org/10.13604/j.cnki.46-1064/r.2021.05.04","url":null,"abstract":"Objective To introduce the process and concrete steps of making dynamic interactive disease\u0000 map using Leaflet program package of R software, and we provide assistance for demonstrating\u0000 the regional distribution of the disease, epidemic analysis and field disposal.\u0000 Methods The address, case classification and date of onset of coronavirus disease 2019 (COVID-19)\u0000 cases, including confirmed and asymptomatic cases, in Hainan as of August 30, 2020\u0000 were collected by Infectious Diseases Reporting System. The addresses of cases were\u0000 input into Amap coordinate pickup system to get the latitude and longitude coordinates\u0000 of the addresses. Amap and Esri map were created as base layers, and case markers,\u0000 function for case clusters and measurement tools were created by leaflet package.\u0000 Results Dynamic interactive map of COVID-19 created by R software could be dragged, be zoomed\u0000 in and out. It can be switched between administrative division map and satellite map.\u0000 The numbers, addresses, onset date and other information could be display by clicking\u0000 the cases in the map. The map can be shared with interested researchers as an html\u0000 file. The distance between any cases or between the case and the suspected exposure\u0000 location could be measured.\u0000 Conclusion As a free and open source software, R software can easily and flexibly make dynamic\u0000 interactive maps of diseases, intuitively and comprehensively display the regional\u0000 distribution of diseases. It It plays a very helpful role in analyzing the transmission\u0000 process of infectious diseases and the on-site treatment of the epidemic situation,\u0000 which is worthy of promotion and application in epidemiology investigation and survey\u0000 research.\u0000 摘要：目的 介绍使用R软件leaflet程序包制作疾病动态交互地图的\u0000 方法 和具体步骤, 为展示疾病的地区分布、疫 情的分析和现场处置提供帮助。\u0000 方法 通过传染病信息报告系统收集海南省截至2020年8月30日新型冠状病毒肺炎 确诊病例和无症状感染者地址、病例分类、发病日期等资料。将病例地址录人髙德地图坐标拾取系统,\u0000 获取病例地址 的经纬度坐标。利用R软件leaflet程序包调用髙德地图、Esri卫星地图做为底图, 添加病例标记, 病例聚合功能及测量 工具。\u0000 结果 R软件制作的海南省新冠病毒动态交互地图可以实现放大、缩小、拖拽等操作, 可以切换行政区划地图和 卫星地图, 点击病例可以显示病例序号, 现住址和发病日期等信息,\u0000 可将地图以html文件方式分享给相关研究人员, 并 可以测量病例间或病例与可疑暴露地点间的距离。\u0000 结论 R软件作为一款免费、开源的软件, 可以简便、灵活的制作 疾病动态交互地图, 直观、全面的展示疾病的地区分布, 对于分析传染病的传播过程、疫情的现场处置起到很好的辅助\u0000 作用, 在流行病学调査研究中值得推广应用。","PeriodicalId":10045,"journal":{"name":"中国热带医学","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79030543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-01DOI: 10.13604/J.CNKI.46-1064/R.2021.04.09
Zhu Yong, Zhou Chao, He Xue-jun, Z. Bo, Lu Sheng, Qiu Jian-ping, Zhou Qiang
Objective To analyze the spatiotemporal distribution and clusters characteristics of human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) patients in Rongchang District of Chongqing from 2014 to 2019, we provide reference for relevant departments to clarify the focus of AIDS prevention and control and rationally allocate medical and health resources. Methods Newly identified HIV/AIDS in Rongchang Area from 2014 to 2019 were selected from the National HIV/AIDS Comprehensive Information System. We inputted data into GeoDa 0.95i software for carry out spatial empirical bayesian smoothing and autocorrelation analysis, and into Satscan 9.3 software for statistical analysis of spatial scanning, and finally geographic information system was used for visualization. Results A total of 1 476 new cases of HIV/AIDS were reported in Rongchang District during 2014–2019. The proportion of cases over the aged ≥50 years reported in each year ranged from 58.74% to 68.92%, and increased year by year (χ 2 trend = 4.524, P = 0.033). There was a positive spatial autocorrelation in the spatial distribution of the HIV/AIDS reporting rate for each year (Moran’s I > 0, P<0.05). The areas with the most serious HIV/AIDS epidemics, including urban areas (Changyuan Street, Changzhou Street) and the neighboring Fenggao Street, Wanling Town, Zhisheng Town and other towns (streets) in the east were Rongchang AIDS-endemic areas, were identified with both the local Moran’s I index and spatiotemporal scan statistics. Conclusion Geographical differences and spatial clustering were identified in HIV/AIDS cases in Rongchang District. For the further prevention and control of the hot-spot regions expanding, the government must strengthen monitoring of the migrating population in hotspots, and strengthen AIDS interventions for middle-aged and elderly people and low-fee sex workers, while further standardize the follow-up management of AIDS in medical institutions at all levels. 摘要：目的 了解2014—2019年重庆市荣昌区艾滋病病毒 ( human immunodeficiency virus, HIV) 感染者和艾滋病 (acquired immune deficiency syndrome, AIDS) 病人(简称HIV/AIDS)的时空分布和聚类特征, 为相关部门明确艾滋病防 控重点及合理配置医疗卫生资源提供参考依据。 方法 在全国艾滋病综合防治信息系统选择2014—2019年现住址为 重庆市荣昌区的HIV/AIDS新发病例信息,导人GeoDa 0.95i软件进行空间经验贝叶斯平滑和空间自相关分析, 导人 Satscan 9.3软件进行时空扫描分析;采用地理信息系统(GIS)实现结果的可视化展示。 结果 2014—2019年, 荣昌区累 计报告HIV/AIDS新发病例1 476例, 各年报告的≥50岁病例数占全部病例的58.74% ~ 68.92%,, 并呈逐年上升趋势 (χ 2 趋势=4.524, P=0.033)。各年HIV/AIDS报告率空间分布均存在正向自相关性 (Moran’s I>0, P<0.05) 。局域空间自相 关和时空扫描统计量综合分析显示城区(昌元街道、昌州街道)和邻近的峰高街道、万灵镇、直升镇等乡镇 (街道)为荣 昌区AIDS流行地区。 结论 荣昌区HIV/AIDS新发病例在地理空间分布上存在聚集性, 各级政府应重点加强城区和邻 近城乡结合部热点区域流动人口 HIV的监测以及中老年人群和低档暗娼人群艾滋病的干预力度, 同时进一步规范各 级医疗机构艾滋病随访管理工作, 防止热点区域的扩大和HIV/AIDS的蔓延。
{"title":"Autocorrelation and spatiotemporal clusters of HIV/AIDS patients in Rongchang District, Chongqing","authors":"Zhu Yong, Zhou Chao, He Xue-jun, Z. Bo, Lu Sheng, Qiu Jian-ping, Zhou Qiang","doi":"10.13604/J.CNKI.46-1064/R.2021.04.09","DOIUrl":"https://doi.org/10.13604/J.CNKI.46-1064/R.2021.04.09","url":null,"abstract":"Objective To analyze the spatiotemporal distribution and clusters characteristics of human\u0000 immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) patients in\u0000 Rongchang District of Chongqing from 2014 to 2019, we provide reference for relevant\u0000 departments to clarify the focus of AIDS prevention and control and rationally allocate\u0000 medical and health resources.\u0000 Methods Newly identified HIV/AIDS in Rongchang Area from 2014 to 2019 were selected from\u0000 the National HIV/AIDS Comprehensive Information System. We inputted data into GeoDa\u0000 0.95i software for carry out spatial empirical bayesian smoothing and autocorrelation\u0000 analysis, and into Satscan 9.3 software for statistical analysis of spatial scanning,\u0000 and finally geographic information system was used for visualization.\u0000 Results A total of 1 476 new cases of HIV/AIDS were reported in Rongchang District during\u0000 2014–2019. The proportion of cases over the aged ≥50 years reported in each year ranged\u0000 from 58.74% to 68.92%, and increased year by year (χ\u0000 2\u0000 trend = 4.524, P = 0.033). There was a positive spatial autocorrelation in the spatial distribution\u0000 of the HIV/AIDS reporting rate for each year (Moran’s I > 0, P<0.05). The areas with the most serious HIV/AIDS epidemics, including urban areas\u0000 (Changyuan Street, Changzhou Street) and the neighboring Fenggao Street, Wanling Town,\u0000 Zhisheng Town and other towns (streets) in the east were Rongchang AIDS-endemic areas,\u0000 were identified with both the local Moran’s I index and spatiotemporal scan statistics.\u0000 Conclusion Geographical differences and spatial clustering were identified in HIV/AIDS cases\u0000 in Rongchang District. For the further prevention and control of the hot-spot regions\u0000 expanding, the government must strengthen monitoring of the migrating population in\u0000 hotspots, and strengthen AIDS interventions for middle-aged and elderly people and\u0000 low-fee sex workers, while further standardize the follow-up management of AIDS in\u0000 medical institutions at all levels.\u0000 摘要：目的 了解2014—2019年重庆市荣昌区艾滋病病毒 (\u0000 human immunodeficiency virus, HIV) 感染者和艾滋病 (acquired immune deficiency syndrome, AIDS) 病人(简称HIV/AIDS)的时空分布和聚类特征,\u0000 为相关部门明确艾滋病防 控重点及合理配置医疗卫生资源提供参考依据。\u0000 方法 在全国艾滋病综合防治信息系统选择2014—2019年现住址为 重庆市荣昌区的HIV/AIDS新发病例信息,导人GeoDa 0.95i软件进行空间经验贝叶斯平滑和空间自相关分析,\u0000 导人 Satscan 9.3软件进行时空扫描分析;采用地理信息系统(GIS)实现结果的可视化展示。\u0000 结果 2014—2019年, 荣昌区累 计报告HIV/AIDS新发病例1 476例, 各年报告的≥50岁病例数占全部病例的58.74% ~ 68.92%,, 并呈逐年上升趋势\u0000 (χ\u0000 2\u0000 趋势=4.524, P=0.033)。各年HIV/AIDS报告率空间分布均存在正向自相关性 (Moran’s I>0, P<0.05) 。局域空间自相 关和时空扫描统计量综合分析显示城区(昌元街道、昌州街道)和邻近的峰高街道、万灵镇、直升镇等乡镇 (街道)为荣 昌区AIDS流行地区。\u0000 结论 荣昌区HIV/AIDS新发病例在地理空间分布上存在聚集性, 各级政府应重点加强城区和邻 近城乡结合部热点区域流动人口 HIV的监测以及中老年人群和低档暗娼人群艾滋病的干预力度,\u0000 同时进一步规范各 级医疗机构艾滋病随访管理工作, 防止热点区域的扩大和HIV/AIDS的蔓延。","PeriodicalId":10045,"journal":{"name":"中国热带医学","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85404017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-01DOI: 10.13604/J.CNKI.46-1064/R.2021.02.04
Lin Xin-mei, H. Ping, Wang Quan-sheng, W. Qun, Yuan Yong-xiao, Wang Yu-fei, Ding Hong-yan
Objective To investigate the correlation between vitamin D and anemia in preschool children in plateau area through the detection of vitamin D and hemoglobin levels in children aged 0–6 years in Daocheng county and Xiangcheng county, Ganzi prefecture, Sichuan province, and we provide scientific basis for the development of measures to prevent anemia in children. Methods Totally 2 122 children, aged 0-6 years were surveyed on the spot of Daocheng county and Xiangcheng county in altitude of 2 000- 0.05). Conclusion The vitamin D level of 2 122 children aged 0-6 years in Daocheng county and Xiangcheng County, Ganzi Prefecture, Sichuan Province, at an altitude of 2 000-4 000 meters, showed a decreasing trend with the increase of age, which was correlated with HGB level. Vitamin D deficiency may be related to the occurrence of anemia. 摘要：目的 对四川省甘孜州稻城县与乡城县0〜6岁儿童血清维生素D及血红蛋白水平的检测, 探讨高原地区0~6岁儿童维生素D与贫血的相关性, 为该地区制定预防儿童贫血措施提供科学依据。 方法 以分层整群随机抽样方法 选取四川省海拔高度在2 000~4 000 m的四川省甘孜州稻城县与乡城县, 选取稻城县与乡城县0~6岁儿童共2 122例, 进行现场问卷、体格检査, 采用高效液相色谱仪和全自动血常规分析仪, 检测血清25-羟维生素D(25-(OH)D)和血红 蛋白 (HGB)含量, 按25-(OH)D含量分为25-(OH)D缺乏组和充足组, 分析25-(OH)D与贫血的关系。 结果 2 122名 0~6岁儿童血清25-(OH)D和血液HGB平均水平分别为 (24.65±6.45) ng/mL和 (132.12±25.31) g/L, 25-(OH)D缺乏率 和贫血率分别为22.6%和22.2%。0~ 0.05)。 结论 海拔高度在 2 000~4 000 m的四川省甘孜州稻城县与乡城县0~6岁儿童25-(OH)D水平偏低, 25-(OH)D缺乏组的HGB水平低于 25-(OH)D充足组, 25-(OH)D缺乏可能是贫血的发生的主要原因。
Objective To investigate the correlation between vitamin D and anemia in preschool children in plateau area through the detection of vitamin D and hemoglobin levels in children aged 0–6 years in Daocheng county and Xiangcheng county, Ganzi prefecture, Sichuan province, and we provide scientific basis for the development of measures to prevent anemia in children. Methods Totally 2 122 children, aged 0-6 years were surveyed on the spot of Daocheng county and Xiangcheng county in altitude of 2 000- 0.05). Conclusion The vitamin D level of 2 122 children aged 0-6 years in Daocheng county and Xiangcheng County, Ganzi Prefecture, Sichuan Province, at an altitude of 2 000-4 000 meters, showed a decreasing trend with the increase of age, which was correlated with HGB level. Vitamin D deficiency may be related to the occurrence of anemia. 摘要：目的 对四川省甘孜州稻城县与乡城县0〜6岁儿童血清维生素D及血红蛋白水平的检测, 探讨高原地区0~6岁儿童维生素D与贫血的相关性, 为该地区制定预防儿童贫血措施提供科学依据。 方法 以分层整群随机抽样方法 选取四川省海拔高度在2 000~4 000 m的四川省甘孜州稻城县与乡城县, 选取稻城县与乡城县0~6岁儿童共2 122例, 进行现场问卷、体格检査, 采用高效液相色谱仪和全自动血常规分析仪, 检测血清25-羟维生素D(25-(OH)D)和血红 蛋白 (HGB)含量, 按25-(OH)D含量分为25-(OH)D缺乏组和充足组, 分析25-(OH)D与贫血的关系。 结果 2 122名 0~6岁儿童血清25-(OH)D和血液HGB平均水平分别为 (24.65±6.45) ng/mL和 (132.12±25.31) g/L, 25-(OH)D缺乏率 和贫血率分别为22.6%和22.2%。0~ 0.05)。 结论 海拔高度在 2 000~4 000 m的四川省甘孜州稻城县与乡城县0~6岁儿童25-(OH)D水平偏低, 25-(OH)D缺乏组的HGB水平低于 25-(OH)D充足组, 25-(OH)D缺乏可能是贫血的发生的主要原因。
{"title":"Survey of vitamin D levels and hemoglobin among children in plateau area, Sichuan","authors":"Lin Xin-mei, H. Ping, Wang Quan-sheng, W. Qun, Yuan Yong-xiao, Wang Yu-fei, Ding Hong-yan","doi":"10.13604/J.CNKI.46-1064/R.2021.02.04","DOIUrl":"https://doi.org/10.13604/J.CNKI.46-1064/R.2021.02.04","url":null,"abstract":"Objective To investigate the correlation between vitamin D and anemia in preschool children in plateau area through the detection of vitamin D and hemoglobin levels in children aged 0–6 years in Daocheng county and Xiangcheng county, Ganzi prefecture, Sichuan province, and we provide scientific basis for the development of measures to prevent anemia in children. Methods Totally 2 122 children, aged 0-6 years were surveyed on the spot of Daocheng county and Xiangcheng county in altitude of 2 000- 0.05). Conclusion The vitamin D level of 2 122 children aged 0-6 years in Daocheng county and Xiangcheng County, Ganzi Prefecture, Sichuan Province, at an altitude of 2 000-4 000 meters, showed a decreasing trend with the increase of age, which was correlated with HGB level. Vitamin D deficiency may be related to the occurrence of anemia. 摘要：目的 对四川省甘孜州稻城县与乡城县0〜6岁儿童血清维生素D及血红蛋白水平的检测, 探讨高原地区0~6岁儿童维生素D与贫血的相关性, 为该地区制定预防儿童贫血措施提供科学依据。 方法 以分层整群随机抽样方法 选取四川省海拔高度在2 000~4 000 m的四川省甘孜州稻城县与乡城县, 选取稻城县与乡城县0~6岁儿童共2 122例, 进行现场问卷、体格检査, 采用高效液相色谱仪和全自动血常规分析仪, 检测血清25-羟维生素D(25-(OH)D)和血红 蛋白 (HGB)含量, 按25-(OH)D含量分为25-(OH)D缺乏组和充足组, 分析25-(OH)D与贫血的关系。 结果 2 122名 0~6岁儿童血清25-(OH)D和血液HGB平均水平分别为 (24.65±6.45) ng/mL和 (132.12±25.31) g/L, 25-(OH)D缺乏率 和贫血率分别为22.6%和22.2%。0~ 0.05)。 结论 海拔高度在 2 000~4 000 m的四川省甘孜州稻城县与乡城县0~6岁儿童25-(OH)D水平偏低, 25-(OH)D缺乏组的HGB水平低于 25-(OH)D充足组, 25-(OH)D缺乏可能是贫血的发生的主要原因。","PeriodicalId":10045,"journal":{"name":"中国热带医学","volume":"515 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75546603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-01DOI: 10.13604/J.CNKI.46-1064/R.2021.02.08
Dou Zheng-dong, Zhang Zheng-hong, Rui Bei
Objective To know the status of quality of life and related factors of adult people living with HIV and AIDS in Wuhu city. Methods The SF-36 questionnaire was used to investigate the 8 dimensions of scores and related characteristics among 869 adult HIV / AIDS follow-ups in Wuhu city during the year of 2018, and the information were associated with infectious disease report card on AIDS. Independent-Samples t test and multiple linear regression model were applied to analyze related factors of physiological scores, psychological scores and overall scores. Results Of 869 participants, the average scores of the SF-36 scale, the physiological aspect, and the psychological aspect were (610.55 ± 120.71) points, (316.09 ± 54.28) points and (294.46 ± 76.19) points, respectively. The scores of physical functioning, role-physical, general health, as well as the overall score of HIV-infected persons were higher than those of AIDS patients ( P <0.05). Multivariate linear regression analysis of SF-36 scale on physiological scores, psychological scores and overall scores of participants showed that numbers of residents ( β =0.183, P <0.001), monthly income ( β =0.174, P <0.001), occupation ( β =0.136, P <0.001), CD4 value ( β =0.099, P =0.002), times of follow-up ( β =0.093, P =0.005) and gender ( β =0.079, P =0.019) affected physiological scores; and monthly income( β =0.274, P <0.001), numbers of residents ( β =0.258, P <0.001), gender ( β =0.063, P <0.001) were related to psychological scores; while monthly income ( β =0.255, P <0.001), numbers of residents ( β =0.251, P <0.001), CD4 values( β =0.077, P <0.001) influenced the overall scores. Conclusion Targeted intervention should be strengthened to improve their quality of life on HIV /AIDS with low-income or no-income, large family-resident population, low CD4 value, less times of follow-up, non-housework occupation or unemployed and female ones. 摘要：目的 了解芜湖市成年HIV感染者/AIDS患者的生存质量现状及其相关因素。 方法 应用SF-36问卷对芜 湖市2018年随访的869名成年HIV感染者/AIDS患者进行调査, 了解8个维度得分情况和相关特征, 关联艾滋病传染病 报卡信息；采用两独立样本t检验和多元线性回归模型分析影响生理 、 心理及总体得分的因素。 结果 869名成年HIV 感染者/AIDS患者的SF-36量表总分、生理及心理得分分别为 (610.55±120.71)、(316.09±54.28)、(294.46±76.19)分。HIV感染者的生理机能、生理职能和一般健康状况维度以及总分均高于AIDS患者( P <0.05)。HIV感染者/AIDS患者家 庭居住人口数( β =0.183, P <0.001)、月收人 ( β =0.174, P <0.001)、职业( β =0.136, P <0.001)、CD4值( β =0.099, P =0.002)、随 访次数( β =0.093, P =0.005)和性别( β =0.079, P =0.019)影响生理得分;月收人( β =0.274, P <0.001)、居住人口数( β =0.258, P <0.001)和性别( β =0.063, P <0.001)影响心理得分；月收人 ( β =0.255, P <0.001)、家庭居住人口数( β =0.251, P <0.001)和 CD4值( β =0.077, P <0.001)影响总体得分。 结论 应关注收人较低或无收人的、家庭居住人口数较多的、CD4值较低 的、随访次数较少的、非家政家务或待业职业的和女性成年HIV感染者/AIDS患者, 加强针对性干预, 提升其生存质量。
目的了解芜湖市成年HIV / AIDS感染者的生活质量现状及相关因素。方法采用SF-36问卷对芜湖市2018年869例成人HIV / AIDS随访者的8个维度得分及相关特征进行调查，并与艾滋病传染病报告卡进行关联。采用独立样本t检验和多元线性回归模型对生理评分、心理评分和总分的相关因素进行分析。结果869名参与者SF-36量表、生理方面和心理方面的平均得分分别为(610.55±120.71)分、(316.09±54.28)分和(294.46±76.19)分。hiv感染者的身体功能、角色身体、一般健康状况及总分均高于艾滋病患者(P <0.05)。SF-36量表生理得分、心理得分和综合得分的多元线性回归分析表明，居民人数(β =0.183, P <0.001)、月收入(β =0.174, P <0.001)、职业(β =0.136, P <0.001)、CD4值(β =0.099, P =0.002)、随访次数(β =0.093, P =0.005)和性别(β =0.079, P =0.019)对生理得分有影响;月收入(β =0.274, P <0.001)、居住人数(β =0.258, P <0.001)、性别(β =0.063, P <0.001)与心理得分相关;月收入(β =0.255, P <0.001)、居民人数(β =0.251, P <0.001)、CD4值(β =0.077, P <0.001)影响总分。结论低收入或无收入、家庭常住人口多、CD4值低、随访次数少、无家务职业或无业、女性等人群应加强针对性干预，提高艾滋病患者的生活质量。hiv / aids / aids /艾滋病方法应用SF-36问卷对芜湖市2018年随访的869名成年艾滋病毒感染者/艾滋病患者进行调査,了解8个维度得分情况和相关特征,关联艾滋病传染病报卡信息,采用两独立样本t检验和多元线性回归模型分析影响生理、心理及总体得分的因素。结果869名成年艾滋病毒感染者/艾滋病患者的SF-36量表总分,生理及心理得分分别为(610.55±120.71),(316.09±54.28),(294.46±76.19)分。艾滋病(aids) (p <0.05)。艾滋病毒感染者/艾滋病患者家庭居住人口数(β= 0.183,P < 0.001),月收人(β= 0.174,P < 0.001),职业(β= 0.136,P < 0.001), CD4值(β= 0.099,P = 0.002),随访次数(β= 0.093,P = 0.005)和性别(β= 0.079,P = 0.019)影响生理得分;月收人(β= 0.274,P < 0.001),居住人口数(β= 0.258,P < 0.001)和性别(β= 0.063,P < 0.001)影响心理得分;月收人(β= 0.255,P < 0.001),家庭居住人口数(β= 0.251,P < 0.001)和CD4值(β= 0.077,P < 0.001)影响总体得分。结论应关注收人较低或无收人的,家庭居住人口数较多的,CD4值较低的,随访次数较少的,非家政家务或待业职业的和女性成年艾滋病毒感染者/艾滋病患者,加强针对性干预,提升其生存质量。
{"title":"Quality of life and related factors among adult people living with HIV/AIDS in Wuhu, Anhui","authors":"Dou Zheng-dong, Zhang Zheng-hong, Rui Bei","doi":"10.13604/J.CNKI.46-1064/R.2021.02.08","DOIUrl":"https://doi.org/10.13604/J.CNKI.46-1064/R.2021.02.08","url":null,"abstract":"Objective To know the status of quality of life and related factors of adult people living with HIV and AIDS in Wuhu city. Methods The SF-36 questionnaire was used to investigate the 8 dimensions of scores and related characteristics among 869 adult HIV / AIDS follow-ups in Wuhu city during the year of 2018, and the information were associated with infectious disease report card on AIDS. Independent-Samples t test and multiple linear regression model were applied to analyze related factors of physiological scores, psychological scores and overall scores. Results Of 869 participants, the average scores of the SF-36 scale, the physiological aspect, and the psychological aspect were (610.55 ± 120.71) points, (316.09 ± 54.28) points and (294.46 ± 76.19) points, respectively. The scores of physical functioning, role-physical, general health, as well as the overall score of HIV-infected persons were higher than those of AIDS patients ( P <0.05). Multivariate linear regression analysis of SF-36 scale on physiological scores, psychological scores and overall scores of participants showed that numbers of residents ( β =0.183, P <0.001), monthly income ( β =0.174, P <0.001), occupation ( β =0.136, P <0.001), CD4 value ( β =0.099, P =0.002), times of follow-up ( β =0.093, P =0.005) and gender ( β =0.079, P =0.019) affected physiological scores; and monthly income( β =0.274, P <0.001), numbers of residents ( β =0.258, P <0.001), gender ( β =0.063, P <0.001) were related to psychological scores; while monthly income ( β =0.255, P <0.001), numbers of residents ( β =0.251, P <0.001), CD4 values( β =0.077, P <0.001) influenced the overall scores. Conclusion Targeted intervention should be strengthened to improve their quality of life on HIV /AIDS with low-income or no-income, large family-resident population, low CD4 value, less times of follow-up, non-housework occupation or unemployed and female ones. 摘要：目的 了解芜湖市成年HIV感染者/AIDS患者的生存质量现状及其相关因素。 方法 应用SF-36问卷对芜 湖市2018年随访的869名成年HIV感染者/AIDS患者进行调査, 了解8个维度得分情况和相关特征, 关联艾滋病传染病 报卡信息；采用两独立样本t检验和多元线性回归模型分析影响生理 、 心理及总体得分的因素。 结果 869名成年HIV 感染者/AIDS患者的SF-36量表总分、生理及心理得分分别为 (610.55±120.71)、(316.09±54.28)、(294.46±76.19)分。HIV感染者的生理机能、生理职能和一般健康状况维度以及总分均高于AIDS患者( P <0.05)。HIV感染者/AIDS患者家 庭居住人口数( β =0.183, P <0.001)、月收人 ( β =0.174, P <0.001)、职业( β =0.136, P <0.001)、CD4值( β =0.099, P =0.002)、随 访次数( β =0.093, P =0.005)和性别( β =0.079, P =0.019)影响生理得分;月收人( β =0.274, P <0.001)、居住人口数( β =0.258, P <0.001)和性别( β =0.063, P <0.001)影响心理得分；月收人 ( β =0.255, P <0.001)、家庭居住人口数( β =0.251, P <0.001)和 CD4值( β =0.077, P <0.001)影响总体得分。 结论 应关注收人较低或无收人的、家庭居住人口数较多的、CD4值较低 的、随访次数较少的、非家政家务或待业职业的和女性成年HIV感染者/AIDS患者, 加强针对性干预, 提升其生存质量。","PeriodicalId":10045,"journal":{"name":"中国热带医学","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84911226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-01DOI: 10.13604/J.CNKI.46-1064/R.2021.02.05
Zheng Wan-ting, Zhong Cheng-wang, Wang Qing-ying, Lin Can-can, Cai Jia-rui, Lin Feng, Zhong You-qing, DU Yong-guo, Wu Biao, X. Sha
Objective To analyze the epidemiological characteristics of 227 patients with melioidosis in three affiliated hospitals of haikou hainan medical college from 2000 to 2019, and we provide theoretical basis for the prevention, treatment and diagnosis of melioidosis. Methods A retrospective investigation was conducted on 227 melioidosis patients, and their epidemiological characteristics, such as gender, age, nationality, occupation, region and time, were analyzed and the subjects were followed up by telephone. Results Among the 227 cases, 202 were males (88.5%) and 26 were females (11.5%). The patients aged 40-<60 years were the most (127, 55.9%). Han nationality were 202 cases, accounted for 89.0%, Li nationality were 23 cases, accounted for 10.1%; Farmers were the main incidence group (91, 40.1%). The most patients were found in Dongfang city (42, 18.5%), followed by Haikou city (41, 18.1%). The onset time of melioidosis was concentrated in summer and autumn, and the peak time of the disease was in September and October. In 2016, the number of patients was the largest (34, 15.0%). The most common admission departments were infectious diseases department with 58 patients (25.6%), followed by respiratory department with 46 patients (20.3%) and surgery department with 30 patients (13.2%). Our results showed that 85.5%(53/62) of the patients recovered, 4.8%(3 cases) experienced recurrence and 9.7%(6 cases) died. Conclusion Middle-aged and old people, people exposed to epidemic water and soil, coastal areas, summer and autumn are the high risk factors of melioidosis. People's awareness of melioidosis should be strengthened and corresponding prevention and treatment should be done well. 摘要：目的 分析海口市海南医学院三家附属医院2000—2019年收治的227例类鼻疽患者的流行病学特征 , 为类 鼻疽的防治、诊断提供理论依据。 方法 对227例类鼻疽患者开展回顾性调査, 分析其性别、年龄、民族、职业、地区、时 间等流行病学特征 , 并对研究对象进行电话随访。 结果 227例类鼻疽患者中, 男性202人, 占88.5%, 女性26人, 占11.5%; 40~<60岁年龄段的患者最多, 127人, 占55.9%;汉族202人, 占89.0%, 黎族23人, 占10.1%;农民为主要患病群 体, 共91人, 占40.1%;患者以东方市分布最多, 42人, 占18.5%, 海口市次之, 41人, 占18.1%。类鼻疽病发病时间集中 于夏秋季, 且9、10月为发病高峰, 2016年患病人数最多, 34人, 占15.0%。最为常见的收治科室为传染科58人, 占 25.6%, 其次为呼吸内科46人 , 占20.3%, 外科30人, 占13.2%。共随访了 62例 , 随访结果显示 , 85.5%(53例) 的患者痊 愈, 4.8%(3例) 出现复发, 9.7%(6例)死亡。 结论 中老年、接触疫水和土壤的人群、沿海地区、夏秋季为类鼻疽的高危 因素, 应加强人们对类鼻疽的认识 , 做好相应的防治工作。
{"title":"Epidemiological investigation of 227 cases of melioidosis patients","authors":"Zheng Wan-ting, Zhong Cheng-wang, Wang Qing-ying, Lin Can-can, Cai Jia-rui, Lin Feng, Zhong You-qing, DU Yong-guo, Wu Biao, X. Sha","doi":"10.13604/J.CNKI.46-1064/R.2021.02.05","DOIUrl":"https://doi.org/10.13604/J.CNKI.46-1064/R.2021.02.05","url":null,"abstract":"Objective To analyze the epidemiological characteristics of 227 patients with melioidosis in three affiliated hospitals of haikou hainan medical college from 2000 to 2019, and we provide theoretical basis for the prevention, treatment and diagnosis of melioidosis. Methods A retrospective investigation was conducted on 227 melioidosis patients, and their epidemiological characteristics, such as gender, age, nationality, occupation, region and time, were analyzed and the subjects were followed up by telephone. Results Among the 227 cases, 202 were males (88.5%) and 26 were females (11.5%). The patients aged 40-<60 years were the most (127, 55.9%). Han nationality were 202 cases, accounted for 89.0%, Li nationality were 23 cases, accounted for 10.1%; Farmers were the main incidence group (91, 40.1%). The most patients were found in Dongfang city (42, 18.5%), followed by Haikou city (41, 18.1%). The onset time of melioidosis was concentrated in summer and autumn, and the peak time of the disease was in September and October. In 2016, the number of patients was the largest (34, 15.0%). The most common admission departments were infectious diseases department with 58 patients (25.6%), followed by respiratory department with 46 patients (20.3%) and surgery department with 30 patients (13.2%). Our results showed that 85.5%(53/62) of the patients recovered, 4.8%(3 cases) experienced recurrence and 9.7%(6 cases) died. Conclusion Middle-aged and old people, people exposed to epidemic water and soil, coastal areas, summer and autumn are the high risk factors of melioidosis. People's awareness of melioidosis should be strengthened and corresponding prevention and treatment should be done well. 摘要：目的 分析海口市海南医学院三家附属医院2000—2019年收治的227例类鼻疽患者的流行病学特征 , 为类 鼻疽的防治、诊断提供理论依据。 方法 对227例类鼻疽患者开展回顾性调査, 分析其性别、年龄、民族、职业、地区、时 间等流行病学特征 , 并对研究对象进行电话随访。 结果 227例类鼻疽患者中, 男性202人, 占88.5%, 女性26人, 占11.5%; 40~<60岁年龄段的患者最多, 127人, 占55.9%;汉族202人, 占89.0%, 黎族23人, 占10.1%;农民为主要患病群 体, 共91人, 占40.1%;患者以东方市分布最多, 42人, 占18.5%, 海口市次之, 41人, 占18.1%。类鼻疽病发病时间集中 于夏秋季, 且9、10月为发病高峰, 2016年患病人数最多, 34人, 占15.0%。最为常见的收治科室为传染科58人, 占 25.6%, 其次为呼吸内科46人 , 占20.3%, 外科30人, 占13.2%。共随访了 62例 , 随访结果显示 , 85.5%(53例) 的患者痊 愈, 4.8%(3例) 出现复发, 9.7%(6例)死亡。 结论 中老年、接触疫水和土壤的人群、沿海地区、夏秋季为类鼻疽的高危 因素, 应加强人们对类鼻疽的认识 , 做好相应的防治工作。","PeriodicalId":10045,"journal":{"name":"中国热带医学","volume":"102 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89745902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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