Medical Reports最新文献

{"title":"Intrauterine device complications: Diagnosis and surgical management of migrated IUDs resulting in uterine and rectal perforation","authors":"Oussama lamzouri ,&nbsp;Reda Rhazi ,&nbsp;Hanae Benchaou ,&nbsp;Chatbi Zainab ,&nbsp;Hafsa Taheri ,&nbsp;Hanane Saadi ,&nbsp;Ahmed Mimouni","doi":"10.1016/j.hmedic.2025.100159","DOIUrl":"10.1016/j.hmedic.2025.100159","url":null,"abstract":"<div><div>Intrauterine devices (IUDs) are widely recognized as highly effective long-term contraceptive methods, providing significant flexibility in usage duration. Available in copper and hormonal variants, IUDs have become increasingly popular due to their convenience and high efficacy rates. Despite these benefits, IUDs can occasionally result in serious complications, including septic infections and uterine perforation, which occurs at an estimated rate of 0.5–1 per 1000 insertions. Uterine perforation, if misdiagnosed, can progress to severe complications such as peritonitis and septic shock. Migrated IUDs can be located in various abdominal regions, including the Douglas pouch, broad ligament, and omentum, with rectal migration being particularly rare and challenging to diagnose and treat. We report two cases of IUD migration resulting in significant clinical presentations. The first case involves a 26-year-old female with hypothyroidism, who presented with six months of cyclic rectal bleeding following the insertion of a copper IUD. Clinical and imaging assessments revealed the IUD had perforated the uterine wall and partially migrated into the rectum. Hysteroscopic removal of the IUD was performed successfully without complications, and the patient recovered uneventfully with prophylactic antibiotic therapy. The second case describes a 30-year-old multiparous female who experienced acute pelvic pain during IUD placement. Subsequent examinations indicated the IUD had migrated into the abdominal cavity. Laparoscopic surgery identified the IUD within the omentum, and it was carefully extracted without damage to surrounding organs. The patient’s recovery was uneventful post-procedure. These cases underscore the importance of recognizing risk factors associated with uterine perforation, such as postpartum insertion and clinician experience. Migrating IUDs can present with a range of symptoms or remain asymptomatic, with diagnosis supported by ultrasound, X-ray, and CT scans. Immediate removal of the displaced IUD is generally recommended to prevent severe complications, with laparoscopy being the preferred retrieval method. The absence of IUD strings during follow-up should prompt immediate suspicion of uterine perforation, necessitating prompt multidisciplinary intervention to mitigate serious outcomes.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100159"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traumatic lacerated lung with diffuse corpora amylacea; the wasteosomes of protection -case report and review of literature","authors":"Aparna Ningombam ,&nbsp;Hemlata Jangir ,&nbsp;Arulselvi Subramanian ,&nbsp;Subodh Garg","doi":"10.1016/j.hmedic.2025.100162","DOIUrl":"10.1016/j.hmedic.2025.100162","url":null,"abstract":"<div><div>Corpora amylacea (CA) has been associated with ageing and various pathological disorders of different organs. Numerous hypotheses and postulates surrounding its origin and functions are available. We report here a case of a traumatic lacerated lung in a 49-year-old male with histopathological findings of diffuse corpora amylacea both intracellularly and extracellularly in the alveoli. The patient recuperated well post-surgical intervention. This case highlights corpora amylacea in the body’s defense and protective mechanism. It is unique as it is usually observed in autopsy findings, but we report these from a surgically resected lung as a management of trauma. It reiterates recent conjecture that these bodies are waste containers or wasteosomes, not only as a part of ageing but in various scenarios of oxidative stress, external factors which advertently activate the ubiquitin-proteasome degradation pathway.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100162"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Creatine Kinase (CK) elevation: An unusual presentation of celiac disease","authors":"Jasmin Martin ,&nbsp;Reshma Patel ,&nbsp;Narayanan Venkatasubramani","doi":"10.1016/j.hmedic.2024.100151","DOIUrl":"10.1016/j.hmedic.2024.100151","url":null,"abstract":"<div><div>Celiac disease (CD) is an autoimmune disorder triggered by ingestion of gluten-containing products. Elevated Creatine Kinase (CK) etiologies include rhabdomyolysis, myocardial infarction or inflammatory myopathies. Very few reports of the association between CD and myopathies. Herein, we reported a 15-year-old with myalgia and weight loss, elevated CK, diagnosed with CD.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100151"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling rifampicin-resistant tuberculosis: A rare presentation as breast abscess in a 48-year-old patient-A case report","authors":"Sandip B. Patil ,&nbsp;Drishti L. Dulani ,&nbsp;Valay N. Ashara ,&nbsp;M. Ramya ,&nbsp;Anil A. Pardeshi","doi":"10.1016/j.hmedic.2025.100161","DOIUrl":"10.1016/j.hmedic.2025.100161","url":null,"abstract":"<div><div><em>Tuberculous mastitis</em> (TM) is a rare manifestation of tuberculosis (TB) that presents challenges in diagnosis and management. We present a case of a 48-year-old female enrolled in the endTB-Q trial who developed rifampicin-resistant TM, masquerading as a breast abscess. Despite a history of drug-sensitive TB and adherence to the antitubercular drug regimen, the patient later developed a breast lump during the trial. Imaging revealed an ill-defined lesion in the right breast, which was later confirmed as tuberculosis through molecular testing. Rifampicin resistance was detected, requiring a tailored treatment approach. The patient responded well to antitubercular therapy and lumpectomy. This highlights the importance of vigilance in diagnosing extrapulmonary TB manifestations, particularly in high TB burden settings. This case underscores the need for multidisciplinary management strategy for atypical presentations of TB.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100161"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An occult primary sclerosing cholangitis unmasked by cholangiography: A case report","authors":"Karam Karam ,&nbsp;Johny Salem ,&nbsp;Sarah Jalloul ,&nbsp;Lynn Daoud ,&nbsp;Pierre Hani","doi":"10.1016/j.hmedic.2025.100168","DOIUrl":"10.1016/j.hmedic.2025.100168","url":null,"abstract":"<div><div>Primary sclerosing cholangitis (PSC) is a chronic and cholestatic liver disease. Inflammation, fibrosis and destruction of intra and extra-hepatic ducts are the hallmarks of PSC. Another similar immune-mediated cholangiopathy is primary biliary cholangitis (PBC) in which only intrahepatic ducts are affected and approximately 90–95 % of patients are found to be positive for anti-mitochondrial antibody (AMA). We herein present a rare case of a 50-year-old female presenting with arthralgias who was found to have anti-mitochondrial antibody (AMA)-positive PSC; a marker usually found to be exclusive to PBC. This manuscript adds an interesting layer of complexity to the differential diagnosis whereby a diagnosis of PSC should not be excluded in the setting of a positive AMA.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100168"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Drug-induced liver injury and the urgent need for improved diagnostic test","authors":"Yoshiyasu Takefuji","doi":"10.1016/j.hmedic.2025.100170","DOIUrl":"10.1016/j.hmedic.2025.100170","url":null,"abstract":"<div><div>A review conducted by the National Library of Medicine has associated antibiotics, antidepressants, and other medications with liver damage. Researchers examined thousands of cases, investigating risk factors, diagnostic challenges, and the role of gut bacteria. They particularly focused on specific medications, including doxycycline and cyclophosphamide. There is an urgent need for the development of more accurate diagnostic tests for human Drug-Induced Liver Injury (DILI). The new findings underscore the necessity for improved diagnostic tools, such as biomarkers, to identify drug-induced liver injury effectively.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100170"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Primary neuro-endocrine carcinoma of the oral cavity – Report of a rare case” [Med. Rep. 9 (2025) 100140]","authors":"Pyne Rudra ,&nbsp;Sil Shiladitya ,&nbsp;Ghosh Subhankar ,&nbsp;Saha Nilanjana","doi":"10.1016/j.hmedic.2024.100150","DOIUrl":"10.1016/j.hmedic.2024.100150","url":null,"abstract":"","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100150"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143348792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Necrosis of the greater omentum: A rare complication after Hartmann's pouch reversal surgery","authors":"Rashed W. Alweshah ,&nbsp;Ibrahim Fathi ,&nbsp;Mostafa M. Farag ,&nbsp;Mohamed Yassin ,&nbsp;Ayman Nabawi","doi":"10.1016/j.hmedic.2024.100149","DOIUrl":"10.1016/j.hmedic.2024.100149","url":null,"abstract":"<div><div>Omental infarction, a rare condition marked by disrupted blood flow to the omentum and subsequent tissue necrosis, is an unusual complication of colorectal surgery. Even more exceptional is its occurrence following Hartmann’s pouch reversal procedure. We present a case of a 32-year-old male patient who was operated on for perforated diverticulitis. An initial sigmoidectomy combined with the creation of a Hartmann's pouch and descending colostomy was performed. Two months later, a Hartmann's reversal procedure was conducted. Four days postoperatively, the patient developed a fever, leukocytosis (26.18 × 10 ³/µL), and foul wound discharge. Computed tomography (CT) revealed suspicion of greater omental necrosis and an omental abscess, which was confirmed during an emergency laparotomy and surgically treated. Postoperatively, the patient was managed with targeted antibiotics, and his recovery was uneventful, leading to discharge in good health. This case highlights the need to consider rare complications such as omental abscesses and necrosis following colorectal surgeries. We discuss the rarity of this complication, its pathophysiology, and review related literature to provide a comprehensive understanding of the condition.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100149"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful mаnаgement of а twisted ovаriаn dermoid cyst during the second trimester of pregnаncy: А cаse report","authors":"Oussama lamzouri ,&nbsp;Imane Benhamou ,&nbsp;Lamyae Errami ,&nbsp;Chatbi Zainab ,&nbsp;Hafsa Taheri ,&nbsp;Hanane Saadi ,&nbsp;Ahmed Mimouni","doi":"10.1016/j.hmedic.2025.100158","DOIUrl":"10.1016/j.hmedic.2025.100158","url":null,"abstract":"<div><div>Ovаriаn torsion is а rаre but serious complicаtion during pregnаncy, pаrticulаrly when аssociаted with lаrge ovаriаn mаsses. This cаse report presents а 42-yeаr-old grаvidа 2 pаrа 1 womаn with а history of cesаreаn section, who presented to the emergency depаrtment аt 16 weeks of gestаtion with аcute аbdominаl pаin. Clinicаl exаminаtion reveаled а pаlpаble left-sided mаss, аnd ultrаsound confirmed аn 11 cm twisted ovаriаn dermoid cyst. Initiаlly, а lаpаroscopic аpproаch wаs аttempted, but due to the lаrge size of the mаss аnd the grаvid uterus, the procedure wаs converted to а lаpаrotomy. А cystectomy wаs successfully performed, preserving the ovаry, аnd histopаthologicаl exаminаtion confirmed а benign dermoid cyst. The pаtient hаd аn uneventful postoperаtive recovery аnd wаs mаnаged with tocolytics to prevent uterine contrаctions. Follow-up ultrаsound demonstrаted а heаlthy intrаuterine pregnаncy, аnd the pаtient continued to receive routine prenаtаl cаre without further complicаtions. This cаse highlights the importаnce of timely intervention in ovаriаn torsion during pregnаncy to prevent potentiаl complicаtions such аs ovаriаn necrosis аnd fetаl loss. Аlthough lаpаroscopy is the preferred surgicаl аpproаch in mаny cаses, this report illustrаtes thаt lаpаrotomy remаins а sаfe аnd effective option when аnаtomicаl constrаints аre present. Surgicаl decision-mаking must be individuаlized bаsed on the size of the mаss, gestаtionаl аge, аnd clinicаl presentаtion to ensure fаvorаble outcomes for both the mother аnd fetus. This cаse underscores the need for flexibility in surgicаl mаnаgement аnd close monitoring postoperаtively.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100158"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Caesarean section in a patient with Aortico pulmonary window: A peculiar case report","authors":"Sandeep Kundra,&nbsp;Snimer K. Sidhu,&nbsp;Shaveta Kundra,&nbsp;Erajot K. Sandhu,&nbsp;Jaspal Kaur","doi":"10.1016/j.hmedic.2024.100142","DOIUrl":"10.1016/j.hmedic.2024.100142","url":null,"abstract":"<div><h3>Background</h3><div>Aortopulmonary window (APW), results from failure of septation of the aorticopulmonary trunk during the fifth to eight weeks of gestational age. Patients with APWs rarely survive beyond early life stages without surgical interventions. Herein, we report anesthetic management of a woman who survived this disorder into adulthood and presented in a pregnant state and was taken up for cesarean delivery.</div></div><div><h3>Case presentation</h3><div>A 29 year female presented with 39 weeks pregnancy. Examination revealed a systolic murmur and cardiomegaly. Echocardiography revealed APW with left to right shunt. An emergency cesarean section under General Anesthesia (GA) was performed due to commencement of labor pains without adequate cervix dilatation.</div></div><div><h3>Conclusion</h3><div>The anesthetic management of a patient with APW is challenging, however, the present case describes the use of general anesthesia with good maternal and neonatal outcomes.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100142"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}