Ameloblastoma is the second most common odontogenic tumour and the most common one to be reported histopathologically. The six histological variants of ameloblastoma are well established in the diagnosis of ameloblastoma, among which desmoplastic type still presents challenges to clinicians. In this multi-centric case series, we have complied with various clinical, radiological and histopathological parameters to better understand a unique variant from cases diagnosed between 1993 and 2023. The calculated mean age for desmoplastic ameloblastoma in the present case series was 55.5 years, with a higher female predilection and two-thirds of cases in the anterior mandible. Radiologically, Type I and II were the predominant presentation. Histopathologically, stromal hyalinization and osteoplasia were noted. The 61.1 % of cases were associated with another sub-type of ameloblastoma. The varied presentation has necessitated a rethink of using newer radiological techniques for early diagnosis, treatment planning and newly defined histopathological criteria for ‘Hybrid’ ameloblastoma.
{"title":"Desmoplastic ameloblastoma: A multicentric study of 18 case series with literature review","authors":"Madhusudan Astekar , Roopa Rao , Karpagaselvi Sanjai , Krishna Sireesha Sundaragiri , Gaurav Sapra , Shylaja Sanjeevareddygari , Srikant Natarajan , Sima P. Odedra","doi":"10.1016/j.hmedic.2024.100148","DOIUrl":"10.1016/j.hmedic.2024.100148","url":null,"abstract":"<div><div>Ameloblastoma is the second most common odontogenic tumour and the most common one to be reported histopathologically. The six histological variants of ameloblastoma are well established in the diagnosis of ameloblastoma, among which desmoplastic type still presents challenges to clinicians. In this multi-centric case series, we have complied with various clinical, radiological and histopathological parameters to better understand a unique variant from cases diagnosed between 1993 and 2023. The calculated mean age for desmoplastic ameloblastoma in the present case series was 55.5 years, with a higher female predilection and two-thirds of cases in the anterior mandible. Radiologically, Type I and II were the predominant presentation. Histopathologically, stromal hyalinization and osteoplasia were noted. The 61.1 % of cases were associated with another sub-type of ameloblastoma. The varied presentation has necessitated a rethink of using newer radiological techniques for early diagnosis, treatment planning and newly defined histopathological criteria for ‘Hybrid’ ameloblastoma.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100148"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.hmedic.2025.100164
Iqra Qazi, Nicole Hancock
Coccidioidomycosis, also known as valley fever, is a fungal infection caused by inhalation of soilborne spores. It primarily affects the respiratory system and presents with symptoms ranging from mild flu-like illness to severe pneumonia. Here we report a case of a 68-year-old male with fevers, worsening fatigue, and rash following a recent COVID-19 diagnosis. The patient had traveled to Florida, Arizona, Mexico, and Nevada within a month prior to symptom onset. Imaging revealed a lung nodule with associated mediastinal lymphadenopathy. Biopsy confirmed disseminated coccidioidomycosis. This case emphasizes the necessity of including coccidioidomycosis in the differential diagnosis for patients with respiratory symptoms and rashes, particularly those with recent travel to endemic regions. Heightened clinical awareness and prompt diagnostic evaluation are crucial for timely management.
{"title":"Disseminated coccidioidomycosis following travel to an endemic region and COVID-19 infection: Case report and case-based literature review","authors":"Iqra Qazi, Nicole Hancock","doi":"10.1016/j.hmedic.2025.100164","DOIUrl":"10.1016/j.hmedic.2025.100164","url":null,"abstract":"<div><div>Coccidioidomycosis, also known as valley fever, is a fungal infection caused by inhalation of soilborne spores. It primarily affects the respiratory system and presents with symptoms ranging from mild flu-like illness to severe pneumonia. Here we report a case of a 68-year-old male with fevers, worsening fatigue, and rash following a recent COVID-19 diagnosis. The patient had traveled to Florida, Arizona, Mexico, and Nevada within a month prior to symptom onset. Imaging revealed a lung nodule with associated mediastinal lymphadenopathy. Biopsy confirmed disseminated coccidioidomycosis. This case emphasizes the necessity of including coccidioidomycosis in the differential diagnosis for patients with respiratory symptoms and rashes, particularly those with recent travel to endemic regions. Heightened clinical awareness and prompt diagnostic evaluation are crucial for timely management.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100164"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Severe serotonin syndrome (SS) secondary to escitalopram is not commonly reported. We present the first case of severe recurrent SS with late-onset seizures following a single escitalopram overdose ingestion.
Case presentation
A 17-year-old girl was referred to the Emergency Department (ED) after allegedly ingesting about 330 mg of escitalopram due to suicidal ideation. She developed mild serotonin syndrome (tremors, hyperreflexia) and prolonged QTc of 620 ms, which resolved within 24 h, and she was discharged after about 48 h of observation. In less than 24 h, she was brought to the ED by her mother due to reduced responsiveness and jerky movement of all limbs. There was no repeated ingestion of escitalopram. On arrival, her Glasgow coma scale (GCS) was full but tachycardic, and she had a temperature of 38 °C, and prolonged QTc (610 ms). In the ED, the patient had myoclonic jerks and fitted (general tonic-clonic) 3 times before being intubated for airway protection. Cyproheptadine was started in the ED as SS symptoms persisted despite multiple diazepam boluses and heavy sedation with midazolam, morphine, and propofol. The serotonin syndrome fully resolved after five days.
Conclusion
Changes in escitalopram’s pharmacokinetics following a massive overdose are unknown. Severe recurrent SS and late-onset seizures can occur up to 72 h following a significant escitalopram overdose ingestion, and the patient should be closely monitored for a longer duration.
{"title":"Severe recurrent serotonin syndrome with late-onset seizures following a single escitalopram overdose ingestion: A case report","authors":"Hock Peng Koh , Nafisah Idris , Muhamad Shazwan Sazali , Paula Suen Suen Teoh","doi":"10.1016/j.hmedic.2024.100153","DOIUrl":"10.1016/j.hmedic.2024.100153","url":null,"abstract":"<div><h3>Introduction</h3><div>Severe serotonin syndrome (SS) secondary to escitalopram is not commonly reported. We present the first case of severe recurrent SS with late-onset seizures following a single escitalopram overdose ingestion.</div></div><div><h3>Case presentation</h3><div>A 17-year-old girl was referred to the Emergency Department (ED) after allegedly ingesting about 330 mg of escitalopram due to suicidal ideation. She developed mild serotonin syndrome (tremors, hyperreflexia) and prolonged QTc of 620 ms, which resolved within 24 h, and she was discharged after about 48 h of observation. In less than 24 h, she was brought to the ED by her mother due to reduced responsiveness and jerky movement of all limbs. There was no repeated ingestion of escitalopram. On arrival, her Glasgow coma scale (GCS) was full but tachycardic, and she had a temperature of 38 °C, and prolonged QTc (610 ms). In the ED, the patient had myoclonic jerks and fitted (general tonic-clonic) 3 times before being intubated for airway protection. Cyproheptadine was started in the ED as SS symptoms persisted despite multiple diazepam boluses and heavy sedation with midazolam, morphine, and propofol. The serotonin syndrome fully resolved after five days.</div></div><div><h3>Conclusion</h3><div>Changes in escitalopram’s pharmacokinetics following a massive overdose are unknown. Severe recurrent SS and late-onset seizures can occur up to 72 h following a significant escitalopram overdose ingestion, and the patient should be closely monitored for a longer duration.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100153"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.hmedic.2024.100140
Pyne Rudra , Sil Shiladitya , Ghosh Subhankar , Saha Nilanjana
Introduction
Neuroectodermal neoplasms include epithelial and non-epithelial types. Small cell neuroendocrine carcinoma (SNEC), primarily a lung cancer, can also appear in the head and neck region. Extra-pulmonary SNECs are rare, with a significant smoking history being a common factor.
Case report
A 60-year-old female presented with a six-month history of painful swelling in the lower right jaw. Examination revealed a firm, tender swelling with tooth mobility and right submandibular lymphadenopathy. Imaging showed a diffuse radiolucent lesion with root resorption. Biopsy and immunohistochemistry confirmed poorly differentiated neuroendocrine carcinoma. The patient underwent partial mandibulectomy and radical neck dissection, followed by adjuvant chemotherapy. A 16-month follow-up showed no recurrence.
Conclusion
Oral cavity SNEC is rare and aggressive, necessitating thorough differential diagnosis. A combination of surgery and chemotherapy is a viable treatment for localized lesions, though standardized protocols are lacking. Enhanced awareness and further research are essential for better diagnostic and therapeutic strategies.
{"title":"Primary Neuro-endocrine Carcinoma of the oral cavity – Report of a rare case","authors":"Pyne Rudra , Sil Shiladitya , Ghosh Subhankar , Saha Nilanjana","doi":"10.1016/j.hmedic.2024.100140","DOIUrl":"10.1016/j.hmedic.2024.100140","url":null,"abstract":"<div><h3>Introduction</h3><div>Neuroectodermal neoplasms include epithelial and non-epithelial types. Small cell neuroendocrine carcinoma (SNEC), primarily a lung cancer, can also appear in the head and neck region. Extra-pulmonary SNECs are rare, with a significant smoking history being a common factor.</div></div><div><h3>Case report</h3><div>A 60-year-old female presented with a six-month history of painful swelling in the lower right jaw. Examination revealed a firm, tender swelling with tooth mobility and right submandibular lymphadenopathy. Imaging showed a diffuse radiolucent lesion with root resorption. Biopsy and immunohistochemistry confirmed poorly differentiated neuroendocrine carcinoma. The patient underwent partial mandibulectomy and radical neck dissection, followed by adjuvant chemotherapy. A 16-month follow-up showed no recurrence.</div></div><div><h3>Conclusion</h3><div>Oral cavity SNEC is rare and aggressive, necessitating thorough differential diagnosis. A combination of surgery and chemotherapy is a viable treatment for localized lesions, though standardized protocols are lacking. Enhanced awareness and further research are essential for better diagnostic and therapeutic strategies.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100140"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.hmedic.2025.100169
Mohammad Ashraful Amin , Ishtiakul Islam Khan , Ridwana Maher Manna , Sumyta Rahman , Nomaan Hassan Khan , Sabrina Nahin , Mohammad Delwer Hossain Hawlader
Adult-onset Still's disease (AOSD) is a rare autoimmune disorder with a challenging diagnosis due to its overlapping symptoms with other inflammatory and infectious conditions. This case study describes a 54-year-old man with type 2 diabetes mellitus who presented with persistent fever, weight loss, and multiple organ involvement. Initial investigations, including imaging and laboratory tests, suggested a granulomatous disease, but a definitive diagnosis remained elusive despite extensive workup. The patient's clinical course, marked by fluctuating symptoms and poor response to conventional treatments, eventually pointed towards an underlying autoimmune disorder. A provisional diagnosis of connective tissue disease with a differential diagnosis of AOSD was made, and corticosteroid therapy was initiated. Complications arose with the development of hemophagocytic lymphohistiocytosis (HLH) or macrophage activation syndrome (MAS), a severe, life-threatening condition associated with AOSD. The patient exhibited high ferritin levels, pancytopenia, and multi-organ dysfunction, indicating HLH. Despite aggressive management, including broad-spectrum antibiotics, antifungal therapy, and high-dose corticosteroids, the patient's condition deteriorated, leading to respiratory distress and arrhythmia. He was transferred to the intensive care unit but unfortunately expired. This case highlights the diagnostic challenges of AOSD and its potential to progress to severe complications like HLH. It underscores the need for a multidisciplinary approach in managing such complex cases and the importance of early recognition and aggressive treatment to improve outcomes. The limitations of conventional therapies and the need for targeted treatments and advanced diagnostic tools are also emphasized for better management of AOSD and associated complications.
{"title":"The Chameleon of rheumatology: A case of adult-onset Still’s disease","authors":"Mohammad Ashraful Amin , Ishtiakul Islam Khan , Ridwana Maher Manna , Sumyta Rahman , Nomaan Hassan Khan , Sabrina Nahin , Mohammad Delwer Hossain Hawlader","doi":"10.1016/j.hmedic.2025.100169","DOIUrl":"10.1016/j.hmedic.2025.100169","url":null,"abstract":"<div><div>Adult-onset Still's disease (AOSD) is a rare autoimmune disorder with a challenging diagnosis due to its overlapping symptoms with other inflammatory and infectious conditions. This case study describes a 54-year-old man with type 2 diabetes mellitus who presented with persistent fever, weight loss, and multiple organ involvement. Initial investigations, including imaging and laboratory tests, suggested a granulomatous disease, but a definitive diagnosis remained elusive despite extensive workup. The patient's clinical course, marked by fluctuating symptoms and poor response to conventional treatments, eventually pointed towards an underlying autoimmune disorder. A provisional diagnosis of connective tissue disease with a differential diagnosis of AOSD was made, and corticosteroid therapy was initiated. Complications arose with the development of hemophagocytic lymphohistiocytosis (HLH) or macrophage activation syndrome (MAS), a severe, life-threatening condition associated with AOSD. The patient exhibited high ferritin levels, pancytopenia, and multi-organ dysfunction, indicating HLH. Despite aggressive management, including broad-spectrum antibiotics, antifungal therapy, and high-dose corticosteroids, the patient's condition deteriorated, leading to respiratory distress and arrhythmia. He was transferred to the intensive care unit but unfortunately expired. This case highlights the diagnostic challenges of AOSD and its potential to progress to severe complications like HLH. It underscores the need for a multidisciplinary approach in managing such complex cases and the importance of early recognition and aggressive treatment to improve outcomes. The limitations of conventional therapies and the need for targeted treatments and advanced diagnostic tools are also emphasized for better management of AOSD and associated complications.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100169"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.hmedic.2025.100167
Amina Hameed, Ranam Akhtar, Khurram Khaliq Bhinder, Ahmad Talha Tariq
Persistent hypoglossal artery (PHA) is a rare vascular variant of carotid-basilar anastomosis, with persistent trigeminal artery being the more common one. It is even rarer in patients with tetralogy of Fallot (TOF) with very few cases reported in the literature. We present a case of a 9-year-old boy diagnosed with Tetralogy of Fallot who presented to the Pediatrics department of Shifa International Hospital with complaints of headache, vomiting and fits. His MRI and serial CT brain imaging were performed, and a diagnosis of brain abscess was made. An incidental note was made of the persistent right hypoglossal artery. He was given IV antibiotics, and significant improvement was seen radiologically as well as clinically. The patient is a potential candidate for Surgical repair of TOF.
{"title":"Enigmatic vessel: The persistent hypoglossal artery in a tetralogy of fallot patient with brain abscess – Report of a rare case","authors":"Amina Hameed, Ranam Akhtar, Khurram Khaliq Bhinder, Ahmad Talha Tariq","doi":"10.1016/j.hmedic.2025.100167","DOIUrl":"10.1016/j.hmedic.2025.100167","url":null,"abstract":"<div><div>Persistent hypoglossal artery (PHA) is a rare vascular variant of carotid-basilar anastomosis, with persistent trigeminal artery being the more common one. It is even rarer in patients with tetralogy of Fallot (TOF) with very few cases reported in the literature. We present a case of a 9-year-old boy diagnosed with Tetralogy of Fallot who presented to the Pediatrics department of Shifa International Hospital with complaints of headache, vomiting and fits. His MRI and serial CT brain imaging were performed, and a diagnosis of brain abscess was made. An incidental note was made of the persistent right hypoglossal artery. He was given IV antibiotics, and significant improvement was seen radiologically as well as clinically. The patient is a potential candidate for Surgical repair of TOF.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100167"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.hmedic.2024.100146
Vivek Manohar Kavila , Jerusha P , Stella Spurthi G , Komali Paruvada
Pregnancy tumor is a reactive hyperplasia of the connective tissue in response to local irritants. Hormonal changes have also been attributed as a likely cause of pregnancy tumors which is frequently seen during pregnancy. Increased levels of sex hormones during pregnancy affect the subgingival microflora, the immune system, the vasculature, and specific cells of the periodontium. This, combined with local irritants, can exacerbate the lesion. Clinically, these lesions appear as tumor-like, non-neoplastic growths in the oral cavity. Pregnancy tumor, typically does not recur after careful surgical excision and the correction of contributing factors. Histopathology plays a crucial role in the diagnosis of the pregnancy tumors. This report presents a case of pregnancy tumor which reoccurred twice in a span of one year postpartum. The patient was followed up for one year after surgical excision, and no recurrence was detected. Recurrence is seldom when local factors are promptly addressed and with thorough surgical excision.
{"title":"Recurrent post-partum pregnancy tumor: A case report","authors":"Vivek Manohar Kavila , Jerusha P , Stella Spurthi G , Komali Paruvada","doi":"10.1016/j.hmedic.2024.100146","DOIUrl":"10.1016/j.hmedic.2024.100146","url":null,"abstract":"<div><div>Pregnancy tumor is a reactive hyperplasia of the connective tissue in response to local irritants. Hormonal changes have also been attributed as a likely cause of pregnancy tumors which is frequently seen during pregnancy. Increased levels of sex hormones during pregnancy affect the subgingival microflora, the immune system, the vasculature, and specific cells of the periodontium. This, combined with local irritants, can exacerbate the lesion. Clinically, these lesions appear as tumor-like, non-neoplastic growths in the oral cavity. Pregnancy tumor, typically does not recur after careful surgical excision and the correction of contributing factors. Histopathology plays a crucial role in the diagnosis of the pregnancy tumors. This report presents a case of pregnancy tumor which reoccurred twice in a span of one year postpartum. The patient was followed up for one year after surgical excision, and no recurrence was detected. Recurrence is seldom when local factors are promptly addressed and with thorough surgical excision.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100146"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.hmedic.2024.100144
Ahmad Jradi , Mohamad Al Qassab , Bachar El Haj Sleiman , Karam Karam , Ihab I. El Hajj , Elias Fiani
Neurofibromatosis Type 1 (NF1), or von Recklinghausen disease, is an autosomal dominant disorder caused by a mutation in the NF1 gene on chromosome 17, leading to neuro-cutaneous manifestations and, in rare cases, visceral involvement. We herein present a rare case of a 16-year-old female with NF1, who presented with persistent gastrointestinal symptoms. Physical examination and imaging revealed a large plexiform neurofibroma in the liver, compressing adjacent organs and causing symptomatic distress. Diagnostic imaging and multidisciplinary evaluation culminated in surgical intervention. Thereafter, we discussed the clinical manifestations, the rare hepatic involvement, diagnostics, and treatments for NF1.
{"title":"An uncanny cause of abdominal pain: A case report of plexiform neurofibromatosis of the liver in a young patient with neurofibromatosis type 1","authors":"Ahmad Jradi , Mohamad Al Qassab , Bachar El Haj Sleiman , Karam Karam , Ihab I. El Hajj , Elias Fiani","doi":"10.1016/j.hmedic.2024.100144","DOIUrl":"10.1016/j.hmedic.2024.100144","url":null,"abstract":"<div><div>Neurofibromatosis Type 1 (NF1), or von Recklinghausen disease, is an autosomal dominant disorder caused by a mutation in the NF1 gene on chromosome 17, leading to neuro-cutaneous manifestations and, in rare cases, visceral involvement. We herein present a rare case of a 16-year-old female with NF1, who presented with persistent gastrointestinal symptoms. Physical examination and imaging revealed a large plexiform neurofibroma in the liver, compressing adjacent organs and causing symptomatic distress. Diagnostic imaging and multidisciplinary evaluation culminated in surgical intervention. Thereafter, we discussed the clinical manifestations, the rare hepatic involvement, diagnostics, and treatments for NF1.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100144"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.hmedic.2024.100145
Ruhus Safa Noor , Md Ismail Gazi , Md Ariful Islam , Md Jobayar Abdien , Tanjina Nasrin , AKM Shamsuddin
Trichotillomania, a condition characterized by compulsive hair-pulling, is recognized as an obsessive-compulsive disorder in the DSM-5. Patients suffering from trichotillomania may develop trichobezoar if not treated early. These hair masses typically form in the stomach, but primary bezoars rarely develop in the small bowel without gastric involvement. This case report presents a 13-year-old girl with a two-month history of abdominal pain, vomiting, and a palpable abdominal mass. History-taking revealed an unusual pattern of scalp hair loss for two years and long familial disharmony. Diagnostic imaging showed a foreign body in the jejunum, which was diagnosed as trichobezoar during laparotomy and was removed surgically. This case emphasizes the need for thorough preoperative evaluation in patients with unexplained gastrointestinal symptoms and the critical importance of early recognition and treatment of trichotillomania to prevent severe complications, such as trichobezoar formation.
{"title":"A neglected case of trichotillomania presenting with jejunal trichobezoar and intestinal obstruction in Bangladesh: A case report","authors":"Ruhus Safa Noor , Md Ismail Gazi , Md Ariful Islam , Md Jobayar Abdien , Tanjina Nasrin , AKM Shamsuddin","doi":"10.1016/j.hmedic.2024.100145","DOIUrl":"10.1016/j.hmedic.2024.100145","url":null,"abstract":"<div><div>Trichotillomania, a condition characterized by compulsive hair-pulling, is recognized as an obsessive-compulsive disorder in the DSM-5. Patients suffering from trichotillomania may develop trichobezoar if not treated early. These hair masses typically form in the stomach, but primary bezoars rarely develop in the small bowel without gastric involvement. This case report presents a 13-year-old girl with a two-month history of abdominal pain, vomiting, and a palpable abdominal mass. History-taking revealed an unusual pattern of scalp hair loss for two years and long familial disharmony. Diagnostic imaging showed a foreign body in the jejunum, which was diagnosed as trichobezoar during laparotomy and was removed surgically. This case emphasizes the need for thorough preoperative evaluation in patients with unexplained gastrointestinal symptoms and the critical importance of early recognition and treatment of trichotillomania to prevent severe complications, such as trichobezoar formation.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100145"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.hmedic.2025.100157
Sikandar Ajmal Abbasi , Muhammad Usama bin Shabbir , Muhammad Soban Bin Salman Meer , Awab-ur-Rehman
"Penile Hair Tourniquet Syndrome" is a rare but potentially severe condition characterized by the constriction of penile tissue by firmly wrapped thread or hair, leading to vascular compromise and tissue damage. This report presents a case of PHTS in a young male child, emphasizing the clinical presentation, diagnostic challenges & management strategies. Early recognition & intervention are critical to avoid complications like necrosis or urethral injury. This case report highlights the importance of considering PHTS in diagnosing penile swelling in children. It highlights the need for increased awareness among caregivers and healthcare providers to ensure early diagnosis and treatment.
{"title":"Hair-thread tourniquet syndrome","authors":"Sikandar Ajmal Abbasi , Muhammad Usama bin Shabbir , Muhammad Soban Bin Salman Meer , Awab-ur-Rehman","doi":"10.1016/j.hmedic.2025.100157","DOIUrl":"10.1016/j.hmedic.2025.100157","url":null,"abstract":"<div><div>\"Penile Hair Tourniquet Syndrome\" is a rare but potentially severe condition characterized by the constriction of penile tissue by firmly wrapped thread or hair, leading to vascular compromise and tissue damage. This report presents a case of PHTS in a young male child, emphasizing the clinical presentation, diagnostic challenges & management strategies. Early recognition & intervention are critical to avoid complications like necrosis or urethral injury. This case report highlights the importance of considering PHTS in diagnosing penile swelling in children. It highlights the need for increased awareness among caregivers and healthcare providers to ensure early diagnosis and treatment.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"9 ","pages":"Article 100157"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143144951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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